{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T12:06:07Z","timestamp":1791979567944,"version":"4.4.0"},"reference-count":10,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2015,8,20]],"date-time":"2015-08-20T00:00:00Z","timestamp":1440028800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J. Med. Toxicol."],"published-print":{"date-parts":[[2016,3]]},"DOI":"10.1007\/s13181-015-0499-3","type":"journal-article","created":{"date-parts":[[2015,8,19]],"date-time":"2015-08-19T15:21:06Z","timestamp":1439997666000},"page":"107-110","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Reversal of Opioid-Induced Ventilatory Depression Using Low-Dose Naloxone (0.04\u00a0mg): a Case Series"],"prefix":"10.1007","volume":"12","author":[{"given":"Hong K.","family":"Kim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lewis S.","family":"Nelson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,8,20]]},"reference":[{"key":"499_CR1","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/S0025-7125(16)33474-5","volume":"48","author":"FF Foldes","year":"1964","unstructured":"Foldes FF. The Human Pharmacology and Clinical Use of Narcotic Antagonists. Med Clin North Am. 1964;48:421\u201343.","journal-title":"Med Clin North Am"},{"issue":"1","key":"499_CR2","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1097\/00063110-200402000-00004","volume":"11","author":"I Buajordet","year":"2004","unstructured":"Buajordet I, Naess AC, Jacobsen D, Brors O. Adverse events after naloxone treatment of episodes of suspected acute opioid overdose. Eur J Emerg Med. 2004;11(1):19\u201323.","journal-title":"Eur J Emerg Med"},{"issue":"2","key":"499_CR3","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/0885-3924(95)00150-6","volume":"11","author":"PL Manfredi","year":"1996","unstructured":"Manfredi PL, Ribeiro S, Chandler SW, Payne R. Inappropriate use of naloxone in cancer patients with pain. J Pain Symptom Manage. 1996;11(2):131\u20134.","journal-title":"J Pain Symptom Manage"},{"key":"499_CR4","first-page":"1230","volume-title":"Tintinalli\u2019s emergency medicine: a comprehensive study guide","author":"S Doyon","year":"2011","unstructured":"Doyon S. Opioids. In: Tintinalli JE, Stapczynski JS, Ma OJ, Cline DM, Cydulka RK, Meckler GD, editors. Tintinalli\u2019s emergency medicine: a comprehensive study guide. 7th ed. New York: McGraw-Hill; 2011. p. 1230\u20133.","edition":"7"},{"key":"499_CR5","first-page":"2052","volume-title":"Rosen\u2019s emergency medicine: concepts and clinical practice","author":"CH Bardsley","year":"2013","unstructured":"Bardsley CH. Opioids. In: Marx JA, Hockberger RS, Walls RM, editors. Rosen\u2019s emergency medicine: concepts and clinical practice. 8th ed. Philadelphia, PA: Elsevier\/Saunders; 2013. p. 2052\u20136.","edition":"8"},{"key":"499_CR6","first-page":"510","volume-title":"Goldfrank\u2019s toxicologic emergencies","author":"LS Nelson","year":"2014","unstructured":"Nelson LS, Howland MA. Antidotes in depth: opioid antagonists. In: Hoffman RS, Howland MA, Lewin NA, Nelson LS, Goldfrank LR, editors. Goldfrank\u2019s toxicologic emergencies. 10th ed. New York: McGraw-Hill Medical; 2014. p. 510\u20135.","edition":"10"},{"issue":"7","key":"499_CR7","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1517\/14740338.2015.1037274","volume":"14","author":"HK Kim","year":"2015","unstructured":"Kim HK, Nelson LS. Reducing the harm of opioid overdose with the safe use of naloxone: a pharmacolgic review. Expert Opin Drug Saf. 2015;14(7):1137\u201346.","journal-title":"Expert Opin Drug Saf"},{"issue":"2","key":"499_CR8","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1056\/NEJMra1202561","volume":"367","author":"EW Boyer","year":"2012","unstructured":"Boyer EW. Management of opioid analgesic overdose. N Engl J Med. 2012;367(2):146\u201355.","journal-title":"N Engl J Med"},{"key":"499_CR9","unstructured":"National Comprehensive Cancer Network. NCCN Clinical Practice Guidelines in Oncology (NCCN guildelines): Adult Cancer Pain. 2014. http:\/\/www.nccn.org\/professionals\/physician_gls\/pdf\/pain.pdf . Accessed 15 Nov 2014"},{"key":"499_CR10","first-page":"76","volume":"10","author":"NC Connors","year":"2014","unstructured":"Connors NC, Nelson LS. Wide variation in naloxone dosing recommendations for acute opioid toxicity. J Med Toxicol. 2014;10:76\u20137.","journal-title":"J Med Toxicol"}],"container-title":["Journal of Medical Toxicology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s13181-015-0499-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s13181-015-0499-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s13181-015-0499-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,3]],"date-time":"2019-06-03T17:22:36Z","timestamp":1559582556000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s13181-015-0499-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,8,20]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,3]]}},"alternative-id":["499"],"URL":"https:\/\/doi.org\/10.1007\/s13181-015-0499-3","relation":{},"ISSN":["1556-9039","1937-6995"],"issn-type":[{"value":"1556-9039","type":"print"},{"value":"1937-6995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,8,20]]}}}