{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T08:53:36Z","timestamp":1768467216468,"version":"3.49.0"},"reference-count":14,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2018,7,26]],"date-time":"2018-07-26T00:00:00Z","timestamp":1532563200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J. Med. Toxicol."],"published-print":{"date-parts":[[2018,12]]},"DOI":"10.1007\/s13181-018-0677-1","type":"journal-article","created":{"date-parts":[[2018,7,26]],"date-time":"2018-07-26T09:20:15Z","timestamp":1532596815000},"page":"323-326","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Dinitrophenol (DNP) Fatality Associated with a Falsely Elevated Salicylate Level: a Case Report with Verification of Laboratory Cross Reactivity"],"prefix":"10.1007","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0991-2730","authenticated-orcid":false,"given":"Kathryn T","family":"Kopec","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caroline","family":"Freiermuth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan","family":"Maynard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Beuhler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2018,7,26]]},"reference":[{"key":"677_CR1","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1007\/s13181-011-0162-6","volume":"7","author":"J Grundlingh","year":"2011","unstructured":"Grundlingh J, Dargan PI, El-Zanfaly M, Wood DM. 2-4-Dinitrophenol (DNP): a weight loss agent with significant acute toxicity and risk of death. J. Med Toxicol. 2011;7:205\u201312.","journal-title":"J. Med Toxicol"},{"key":"677_CR2","doi-asserted-by":"crossref","unstructured":"Holborow A, Purnell RM, Wong JF. Beware the yellow slimming pill: fatal 2,4-dinitrophenol overdose. BMJ Case Rep. 2016:1\u20133.","DOI":"10.1136\/bcr-2016-214689"},{"key":"677_CR3","unstructured":"McFee RB, Caraccio TP, McGuigan, Reynolds SA, Bellanger P. Dying to be thin: a Dinitrophenol related fatality. Vet Human Toxicology. Oct;46(5):251\u20134."},{"key":"677_CR4","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1136\/emermed-2013-203335","volume":"32","author":"A Kamour","year":"2015","unstructured":"Kamour A, George N, Gwynnette D, Cooper G, Lupton D, Eddleston M, et al. Increasing frequency of severe clinical toxicity after use of 2,4-Dinitrophenol in the UK: a report from the National Poisons Information Service. Emerg Med J. 2015;32:383\u20136.","journal-title":"Emerg Med J"},{"key":"677_CR5","first-page":"281","volume":"43","author":"AL Hsiao","year":"2005","unstructured":"Hsiao AL, Santucci KA, Seo-Mayer P, Mariappan MR, Hodsdon ME, Banasiak KJ, et al. Pediatric fatality following ingestion of Dinitrophenol: postmortem identification of a \u201cDietary Supplement\u201d. Clin Toxicol. 2005;43:281\u20135.","journal-title":"Clin Toxicol"},{"issue":"2","key":"677_CR6","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1097\/00007611-198202000-00016","volume":"75","author":"RB Leftwich","year":"1982","unstructured":"Leftwich RB, Floro JF, Neal RA, Wood AJJM. Dinitrophenol poisoning: a diagnosis to consider in undiagnosed fever. South Med J. 1982;75(2):182\u20134.","journal-title":"South Med J"},{"key":"677_CR7","unstructured":"Roberts, JR, Reigart, JR. \u201cPentachlorophenol and Dinitrophenolic pesticides.\u201d Recognition and Management of Pesticide Poisonings. 6th Ed. United States Environmental Protection Agency: Office of Pesticide Programs. 2013. Chapter 11:103\u2013109."},{"issue":"2","key":"677_CR8","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1097\/00006565-199804000-00012","volume":"14","author":"AJ Macnab","year":"1998","unstructured":"Macnab AJ, Fielden SJ. Successful treatment of dinitrophenol poisoning in a child. Pediatr Emerg Care. 1998;14(2):136\u20138.","journal-title":"Pediatr Emerg Care"},{"key":"677_CR9","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1016\/j.emc.2007.02.012","volume":"25","author":"GF O\u2019Malley","year":"2007","unstructured":"O\u2019Malley GF. Emergency department management of the salicylate-poisoned patient. Emerg Med Clin N Am. 2007;25:333\u201346.","journal-title":"Emerg Med Clin N Am"},{"issue":"2","key":"677_CR10","doi-asserted-by":"publisher","first-page":"536","DOI":"10.1016\/j.neuropharm.2006.07.037","volume":"52","author":"M Watabe","year":"2007","unstructured":"Watabe M, Nakaki T. ATP depletion does not account for apoptosis induced by inhibition of mitochondrial electron transport chain in human dopaminergic cells. Neuropharmacology. 2007;52(2):536\u201341.","journal-title":"Neuropharmacology"},{"issue":"3","key":"677_CR11","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1093\/jat\/30.3.219","volume":"30","author":"EJ Miranda","year":"2006","unstructured":"Miranda EJ, McIntyre IM, Parker DR, Gary RK, Logan BK. Two deaths attributed to the use of 2,4-Dinitrophenol. J Anal Toxicol. 2006;30(3):219\u201322.","journal-title":"J Anal Toxicol"},{"issue":"4","key":"677_CR12","doi-asserted-by":"publisher","first-page":"566","DOI":"10.1093\/bja\/aep033","volume":"102","author":"A Tewari","year":"2009","unstructured":"Tewari A, Ali A, O\u2019Donnel AS, Butt M. Weight loss and 2,4-Dinitrophenol poisoning. Br J Anaesth. 2009;102(4):566\u20137.","journal-title":"Br J Anaesth"},{"key":"677_CR13","unstructured":"2,4-Dinitrophenol. National Center for Biotechnology Information PubChem Compound Database; CID=1493, \n                    https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/1493\n                    \n                   (accessed Apr. 11, 2018)."},{"key":"677_CR14","unstructured":"Agency for Toxic Substances and Disease Registry (ATSDR). 1995. Toxicological profile for Dinitrophenols. Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service. \n                    https:\/\/www.atsdr.cdc.gov\/toxprofiles\/TP.asp?id=729&tid=132\n                    \n                  , \n                    https:\/\/www.atsdr.cdc.gov\/toxprofiles\/tp64-c2.pdf"}],"container-title":["Journal of Medical Toxicology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s13181-018-0677-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s13181-018-0677-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s13181-018-0677-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,25]],"date-time":"2019-07-25T19:28:01Z","timestamp":1564082881000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s13181-018-0677-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,26]]},"references-count":14,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,12]]}},"alternative-id":["677"],"URL":"https:\/\/doi.org\/10.1007\/s13181-018-0677-1","relation":{},"ISSN":["1556-9039","1937-6995"],"issn-type":[{"value":"1556-9039","type":"print"},{"value":"1937-6995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,26]]},"assertion":[{"value":"14 May 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 July 2018","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 July 2018","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 July 2018","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Consent was not available, but this case was\u00a0anonymized according to JMT guidelines and publication was approved after review by members of the editorial board because the manuscript primarily focuses on the laboratory issues identified by this clinical event.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"None.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of Interest"}}]}}