{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T15:17:31Z","timestamp":1793459851890,"version":"4.5.0"},"reference-count":52,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2019,5,6]],"date-time":"2019-05-06T00:00:00Z","timestamp":1557100800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J. Med. Toxicol."],"published-print":{"date-parts":[[2019,10]]},"DOI":"10.1007\/s13181-019-00710-5","type":"journal-article","created":{"date-parts":[[2019,5,7]],"date-time":"2019-05-07T11:23:48Z","timestamp":1557228228000},"page":"287-294","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":113,"title":["Hydrogen Sulfide Toxicity: Mechanism of Action, Clinical Presentation, and Countermeasure Development"],"prefix":"10.1007","volume":"15","author":[{"given":"Patrick C.","family":"Ng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tara B.","family":"Hendry-Hofer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alyssa E.","family":"Witeof","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Brenner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sari B.","family":"Mahon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerry R.","family":"Boss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Haouzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vikhyat S.","family":"Bebarta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,5,6]]},"reference":[{"key":"710_CR1","unstructured":"OSHAFactSheet, U.S. Department of Labor. Available at: https:\/\/www.osha.gov\/OshDoc\/data_Hurricane_Facts\/hydrogen_sulfide_fact.pdf . Last accessed: November 9, 2018."},{"issue":"11","key":"710_CR2","first-page":"1277","volume":"117","author":"WW Burnett","year":"1977","unstructured":"Burnett WW, King EG, Grace M, Hall WF. Hydrogen sulfide poisoning: review of 5 years\u2019 experience. Can Med Assoc J. 1977;117(11):1277\u201380.","journal-title":"Can Med Assoc J"},{"issue":"5","key":"710_CR3","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1097\/00043764-198505000-00018","volume":"27","author":"IM Arnold","year":"1985","unstructured":"Arnold IM, Dufresne RM, Alleyne BC, Stuart PJ. Health implication of occupational exposures to hydrogen sulfide. J Occup Med. 1985;27(5):373\u20136.","journal-title":"J Occup Med"},{"issue":"3","key":"710_CR4","first-page":"300","volume":"12","author":"SJ Reddy","year":"2011","unstructured":"Reddy SJ, Schwartz MD, Morgan BW. Suicide fads: frequency and characteristics of hydrogen sulfide suicides in the United States. West J Emerg Med. 2011;12(3):300\u20134.","journal-title":"West J Emerg Med"},{"issue":"6","key":"710_CR5","doi-asserted-by":"publisher","first-page":"680","DOI":"10.5811\/westjem.2016.9.32267","volume":"17","author":"AR Anderson","year":"2016","unstructured":"Anderson AR. Characterization of chemical suicides in the United States and its adverse impact on responders and bystanders. West J Emerg Med. 2016;17(6):680\u20133.","journal-title":"West J Emerg Med"},{"key":"710_CR6","unstructured":"TSA issues Security Awareness Message on potential use of H2S in terrorist attack. Hazmat\/Safety. Bulk Transporter. Available at: https:\/\/www.bulktransporter.com\/hazmatsafety\/tsa-issues-security-awareness-message-potential-use-h2s-terrorist-attack . Last Accessed 5 Nov 2018."},{"key":"710_CR7","unstructured":"Strickland J, Cummings A, Spinnato JA, Liccione JJ, Foureman GL. Toxicological review of hydrogen sulfide. U.S. Environmental Protection Agency, Washington, DC. June 2003. Available at: https:\/\/cfpub.epa.gov\/ncea\/iris\/iris_documents\/documents\/toxreviews\/0061tr.pdf . Last Accessed 30 Mar 2019."},{"key":"710_CR8","unstructured":"Hydrogen sulfide: a potential first responder hazard. New York State office of Homeland Security, Emergency Managers Advisory. Available at: https:\/\/info.publicintelligence.net\/NYhydrogensulfide.pdf . Last Accessed 5 Nov 2018."},{"issue":"4","key":"710_CR9","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1002\/ajim.10355","volume":"45","author":"RG Hendrickson","year":"2004","unstructured":"Hendrickson RG, Chang A, Hamilton RJ. Co-worker fatalities from hydrogen sulfide. Am J Ind Med. 2004;45(4):346\u201350.","journal-title":"Am J Ind Med"},{"key":"710_CR10","unstructured":"Edinburgh: Blackwood & Sons, Williams J. Australia details \u2018sophisticated\u2019 plot by ISIS to take down plane. New York Times [News], 2017. Available at: https:\/\/www.nytimes.com\/2017\/08\/04\/world\/australia\/sydney-airport-terror-plot-isis.html . Last Accessed 14 Mar 2018."},{"key":"710_CR11","unstructured":"McKirdy E, Smith K. Foiled plot to blow up plane, unleash gas revealed in Australia. CNN World. Available at: https:\/\/www.cnn.com\/2017\/08\/03\/asia\/australia-plane-terror-plot-isis\/index.html . Last Accessed 5 Nov 2018."},{"issue":"3","key":"710_CR12","doi-asserted-by":"publisher","first-page":"1066","DOI":"10.1523\/JNEUROSCI.16-03-01066.1996","volume":"16","author":"K Abe","year":"1996","unstructured":"Abe K, Kimura H. The possible role of hydrogen sulfide as an endogenous neuromodulator. J Neurosci. 1996;16(3):1066\u201371.","journal-title":"J Neurosci"},{"issue":"10","key":"710_CR13","doi-asserted-by":"publisher","first-page":"1773","DOI":"10.1177\/00220345000790100701","volume":"79","author":"FL Suarez","year":"2000","unstructured":"Suarez FL, Furne JK, Springfield J, Levitt MD. Morning breath odor: influence of treatments of sulfur gases. J Dent Res. 2000;79(10):1773\u20137.","journal-title":"J Dent Res"},{"issue":"9","key":"710_CR14","doi-asserted-by":"publisher","first-page":"833","DOI":"10.1113\/expphysiol.2011.057455","volume":"96","author":"H Kimura","year":"2011","unstructured":"Kimura H. Hydrogen sulfide: its production and functions. Exp Physiol. 2011;96(9):833\u20135.","journal-title":"Exp Physiol"},{"key":"710_CR15","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/S0021-9258(18)85985-3","volume":"49","author":"HW Haggard","year":"1921","unstructured":"Haggard HW. The fate of sulfides in the blood. J Biol Chem. 1921;49:519\u201329.","journal-title":"J Biol Chem"},{"key":"710_CR16","first-page":"R630","volume":"305","author":"CM Klingerman","year":"2013","unstructured":"Klingerman CM, Trushin N, Prokopczyk B, Haouzi P. H2S concentrations in the arterial blood during H2S administration in relation to its toxicity and effects on breathing. Am J Phys Regul Integr Comp Phys. 2013;305:R630\u20138.","journal-title":"Am J Phys Regul Integr Comp Phys"},{"issue":"2","key":"710_CR17","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1093\/toxsci\/kfu140","volume":"141","author":"P Haouzi","year":"2014","unstructured":"Haouzi P, Sonobe T, Torsell-Tubbs N, Prokopczyk B, Chenuel B, Klingerman CM. In vivo interactions between cobalt or ferric compounds and the pools of sulphide in the blood during and after H2S poisoning. Toxicol Sci. 2014;141(2):493\u2013504.","journal-title":"Toxicol Sci"},{"key":"710_CR18","doi-asserted-by":"publisher","first-page":"3352","DOI":"10.1111\/j.1742-4658.2008.06482.x","volume":"275","author":"TM Hildebrandt","year":"2008","unstructured":"Hildebrandt TM, Grieshaber MK. Three enzymatic activities catalyze oxidation of sulfide to thiosulfate in mammalian and invertebrate mitochondria. FEBS J. 2008;275:3352\u201361.","journal-title":"FEBS J"},{"issue":"1","key":"710_CR19","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1089\/ars.2011.4401","volume":"17","author":"KR Olson","year":"2012","unstructured":"Olson KR. A practical look at the chemistry and biology of hydrogen sulfide. Antioxid Redox Signal. 2012;17(1):32\u201344.","journal-title":"Antioxid Redox Signal"},{"key":"710_CR20","doi-asserted-by":"publisher","first-page":"1163","DOI":"10.1016\/0016-7037(89)90053-7","volume":"53","author":"JJ Carroll","year":"1989","unstructured":"Carroll JJ, Mather AE. The solubility of hydrogensulphide in water from 0-90C and pressures to 1Mpa. Geochim Cosmochin Acta. 1989;53:1163\u201370.","journal-title":"Geochim Cosmochin Acta"},{"key":"710_CR21","doi-asserted-by":"publisher","first-page":"7245","DOI":"10.1029\/95JD00217","volume":"100","author":"WJ DeBruyn","year":"1995","unstructured":"DeBruyn WJ, Swartz E, Hu JH, Shorter JA, Davidovits P, Worsnop DR, et al. Henry\u2019s law solubilities and Setchenow coefficients for biogenic reduced sulfur species obtained from gas-liquid uptake measurements. J Geophys Res. 1995;100:7245\u201351.","journal-title":"J Geophys Res"},{"key":"710_CR22","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1146\/annurev.pa.32.040192.000545","volume":"32","author":"RJ Reiffenstein","year":"1992","unstructured":"Reiffenstein RJ, Hurlbert WC, Roth SH. Toxicology of hydrogen sulfide. Annu Rev Pharmacol Toxicol. 1992;32:109\u201313.","journal-title":"Annu Rev Pharmacol Toxicol"},{"issue":"1","key":"710_CR23","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1111\/nyas.13015","volume":"1374","author":"P Haouzi","year":"2016","unstructured":"Haouzi P, Sonobe T, Judenjerc-Haouzi A. Developing effective countermeasures against acute hydrogen sulfide intoxication: challenges and limitations. Ann NY Aca Sci. 2016;1374(1):29\u201340.","journal-title":"Ann NY Aca Sci"},{"key":"710_CR24","doi-asserted-by":"publisher","first-page":"20831","DOI":"10.1038\/srep20831","volume":"6","author":"J Jiang","year":"2016","unstructured":"Jiang J, Chan A, Ali S, Saha A, Haushalter JK, Lam WL, et al. Hydrogen sulfide\u2014mechanisms of toxicity and development of an antidote. Sci Rep. 2016;6:20831.","journal-title":"Sci Rep"},{"issue":"1\u20133","key":"710_CR25","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/j.tox.2004.05.020","volume":"203","author":"MA Eghbal","year":"2004","unstructured":"Eghbal MA, Pennefather PS, O\u2019Brien PJ. H2S cytotoxicity mechanism involves reactive oxygen species formation and mitochondrial depolarisation. Toxicology. 2004;203(1\u20133):69\u201376.","journal-title":"Toxicology"},{"issue":"5","key":"710_CR26","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1007\/s12012-018-9451-5","volume":"18","author":"JY Cheung","year":"2018","unstructured":"Cheung JY, Wang J, Zhang XQ, Song J, Davidyock M, Prado FJ, et al. Methylene blue counteracts H2S induced cardiac ion channel dysfunction and ATP reduction. Cardiovasc Toxicol. 2018;18(5):407\u201319.","journal-title":"Cardiovasc Toxicol"},{"key":"710_CR27","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1016\/j.neuroscience.2012.05.044","volume":"218","author":"H Ogawa","year":"2012","unstructured":"Ogawa H, Takahashi K, Miura S, Imagawa T, Saito S, Tominaga M, et al. H2S functions as a nociceptive messenger through transient receptor potential Ankyrin 1 (TRPA1) activation. Neuroscience. 2012;218:335\u201343.","journal-title":"Neuroscience"},{"key":"710_CR28","doi-asserted-by":"publisher","first-page":"4643","DOI":"10.1016\/j.ejphar.2015.07.029","volume":"764","author":"A Ujike","year":"2015","unstructured":"Ujike A, Otsuguro K, Miyamoto R, Yamaguchi S, Ito S. Bidirectional effects of hydrogen sulfide via ATP-sensitive K+ channels and transient receptor potential A1 channels in RIN14B cells. Euro J Pharmacol. 2015;764:4643\u2013470.","journal-title":"Euro J Pharmacol"},{"key":"710_CR29","doi-asserted-by":"crossref","unstructured":"Steinritz D, Stenger B, Dietrich A, Gudermann T, Popp T. TRPs in Tox: involvement of transient receptor potential-channels in chemical induced organ toxicity\u2014a structured review. Cells 2018 ; 7(8).","DOI":"10.3390\/cells7080098"},{"issue":"1","key":"710_CR30","doi-asserted-by":"publisher","first-page":"25","DOI":"10.3109\/10408448409029321","volume":"13","author":"RO Beauchamp","year":"1984","unstructured":"Beauchamp RO, Bus JS, Popp JA, Boreiko CJ, Andjelkovich DA. A critical review of the literature on hydrogen sulfide toxicity. Crit Rev Toxicol. 1984;13(1):25\u201397.","journal-title":"Crit Rev Toxicol"},{"issue":"1","key":"710_CR31","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1111\/nyas.13419","volume":"1400","author":"P Anantharam","year":"2017","unstructured":"Anantharam P, Whitley EM, Mahama B, Kim DS, Imerman PM, Shao D, et al. Characterizing a mouse model for evaluation of countermeasures against hydrogen sulfide-induced neurotoxicity and neurological sequelae. Ann N Y Acad Sci. 2017;1400(1):46\u201364.","journal-title":"Ann N Y Acad Sci"},{"issue":"3","key":"710_CR32","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1080\/15563650.2018.1504955","volume":"57","author":"PC Ng","year":"2019","unstructured":"Ng PC, Hendry-Hofer TB, Garrett N, Brenner M, Mahon SB, Maddry JK, et al. Intramuscular cobinamide versus saline for treatment of severe hydrogen sulfide toxicity in swine. Clin Toxicol. 2019;57(3):189\u201396.","journal-title":"Clin Toxicol"},{"key":"710_CR33","first-page":"194","volume":"11","author":"W Scheler","year":"1963","unstructured":"Scheler W, Kabisch R. The antagonistic effect on the acute H2S-toxication in mice by methemoglobin-forming agents. Acta Biol Med Ger. 1963;11:194\u20139.","journal-title":"Acta Biol Med Ger"},{"issue":"1","key":"710_CR34","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1016\/0041-008X(66)90112-8","volume":"8","author":"RP Smith","year":"1966","unstructured":"Smith RP, Gosselin RE. On the mechanism of sulfide inactivation by methemoglobin. Toxicol Appl Pharmacol. 1966;8(1):159\u201372.","journal-title":"Toxicol Appl Pharmacol"},{"issue":"11","key":"710_CR35","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1080\/15298668191420738","volume":"42","author":"JF Beck","year":"1981","unstructured":"Beck JF, Bradbury CM, Connors AJ, Donini JC. Nitrite as an antidote for acute hydrogen sulfide intoxication? Am Ind Hyg Assoc J. 1981;42(11):805\u20139.","journal-title":"Am Ind Hyg Assoc J"},{"issue":"7","key":"710_CR36","doi-asserted-by":"publisher","first-page":"1398","DOI":"10.1021\/acs.chemrestox.5b00015","volume":"28","author":"AA Cronican","year":"2015","unstructured":"Cronican AA, Frawley KL, Ahmed H, Pearce LL, Peterson J. Antagonism of acute sulfide poisoning in mice by nitrite anion without methemoglobinemia. Chem Res Toxicol. 2015;28(7):1398\u2013408.","journal-title":"Chem Res Toxicol"},{"issue":"5","key":"710_CR37","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1007\/s12012-018-9454-2","volume":"18","author":"A Judenherc-Haouzi","year":"2018","unstructured":"Judenherc-Haouzi A, Sonobe T, Bebarta VS, Haouzi P. On the efficacy of cardio-pulmonary resuscitation and epinephrine following cyanide- and H2S intoxication-induced cardiac asystole. Cardiovasc Toxicol. 2018;18(5):436\u201349.","journal-title":"Cardiovasc Toxicol"},{"issue":"1\u20133","key":"710_CR38","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1016\/j.tox.2007.09.009","volume":"242","author":"DH Truong","year":"2007","unstructured":"Truong DH, Mihajlovic A, Gunness P, Hindmarsh W, O\u2019Brien PJ. Prevention of hydrogen sulfide (H2S)- induced mouse lethality and cytotoxicity by hydroxocobalamin. Toxicology. 2007;242(1\u20133):16\u201322.","journal-title":"Toxicology"},{"issue":"1","key":"710_CR39","doi-asserted-by":"publisher","first-page":"28","DOI":"10.3109\/15563650.2014.990976","volume":"53","author":"P Haouzi","year":"2015","unstructured":"Haouzi P, Chenuel B, Sonobe T. High dose hydroxocobalamin administered after H2S exposure counteracts sulfide poisoning induced cardiac depression in sheep. Clin Toxicol(Phila). 2015;53(1):28\u201336.","journal-title":"Clin Toxicol(Phila)"},{"issue":"5","key":"710_CR40","doi-asserted-by":"publisher","first-page":"490","DOI":"10.3109\/15563650.2014.904045","volume":"52","author":"M Brenner","year":"2014","unstructured":"Brenner M, Benavides S, Mahob SB, Lee J, Yoon D, Mukai D, et al. The vitamin b12 analog cobinamide is an effective hydrogen sulfide antidote in a lethal rabbit model. Clin Toxicol(Phila). 2014;52(5):490\u20137.","journal-title":"Clin Toxicol(Phila)"},{"issue":"9","key":"710_CR41","doi-asserted-by":"publisher","first-page":"1088","DOI":"10.1111\/acem.13213","volume":"24","author":"VS Bebarta","year":"2017","unstructured":"Bebarta VS, Garrett N, Brenner M, Mahon SB, Maddry JK, Boudreau S, et al. Efficacy of intravenous cobinamide versus hydroxocobalamin or saline for treatment of severe hydrogen sulfide toxicity in a swine (Sus scrofa ) model. Acad Emerg Med. 2017;24(9):1088\u201398.","journal-title":"Acad Emerg Med"},{"issue":"25","key":"710_CR42","doi-asserted-by":"publisher","first-page":"4123","DOI":"10.1002\/ejic.201402082","volume":"2014","author":"DS Salnikov","year":"2014","unstructured":"Salnikov DS, Makarov SV, Eldik R, Kucherenko PN, Boss GR. Kinetics and mechanism of the reaction of hydrogen sulfide with diaquacobinamide in aqueous solution. Eur J Inorg Chem. 2014;2014(25):4123\u201333.","journal-title":"Eur J Inorg Chem"},{"issue":"4","key":"710_CR43","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1007\/s13181-016-0566-4","volume":"12","author":"J Lee","year":"2016","unstructured":"Lee J, Mahon SB, Mukai D, Burney T, Katebian BS, Chan A, et al. The vitamin B12 analog cobinamide is an effective antidote for oral cyanide poisoning? J Med Toxicol. 2016;12(4):370\u20139.","journal-title":"J Med Toxicol"},{"issue":"6","key":"710_CR44","doi-asserted-by":"publisher","first-page":"612","DOI":"10.1016\/j.annemergmed.2014.02.009","volume":"64","author":"VS Bebarta","year":"2014","unstructured":"Bebarta VS, Tanen DA, Boudreau S, Castaneda M, Zarzabal LA, Vargas T, et al. Intravenous cobinamide versus hydroxocobalamin for acute treatment of severe cyanide poisoning in a swine (Sus scrofa) model. Ann Emerg Med. 2014;64(6):612\u20139.","journal-title":"Ann Emerg Med"},{"issue":"1","key":"710_CR45","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1007\/s13181-017-0650-4","volume":"14","author":"P Anantharam","year":"2018","unstructured":"Anantharam P, Kim DS, Whitley EM, Mahama B, Imerman P, Padhi P, et al. Midazolam efficacy against acute hydrogen sulfide-induced mortality and neurotoxicity. J Med Toxicol. 2018;14(1):79\u201390.","journal-title":"J Med Toxicol"},{"issue":"11","key":"710_CR46","first-page":"R1030","volume":"310","author":"A Judenherc-Haouzi","year":"2016","unstructured":"Judenherc-Haouzi A, Zhang XQ, Sonobe T, Song J, Rannals MD, Wang J, et al. Methylene blue counteracts H2S toxicity-induced cardiac depression by restoring L-type Ca channel activity. Am J Phys Regul Integr Comp Phys. 2016;310(11):R1030\u201344.","journal-title":"Am J Phys Regul Integr Comp Phys"},{"issue":"2","key":"710_CR47","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1093\/toxsci\/kfy308","volume":"168","author":"P Haouzi","year":"2019","unstructured":"Haouzi P, Tubbs N, Cheung J, Judenherc-Haouzi A. Methylene blue administration during and after life-threatening intoxication by hydrogen sulfide: efficacy studies in adult sheep and mechanisms of action. Toxicol Sci. 2019;168(2):443\u201359.","journal-title":"Toxicol Sci"},{"issue":"4","key":"710_CR48","doi-asserted-by":"publisher","first-page":"733","DOI":"10.1080\/03602530600959607","volume":"38","author":"DH Truong","year":"2006","unstructured":"Truong DH, Eghbal MA, Hindmarsh W, Roth SH, O\u2019Brien PJ. Molecular mechanisms of hydrogen sulfide toxicity. Drug Metab Rev. 2006;38(4):733\u201344.","journal-title":"Drug Metab Rev"},{"key":"710_CR49","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1016\/B978-0-444-62627-1.00008-1","volume":"131","author":"TL Guidotti","year":"2015","unstructured":"Guidotti TL. Hydrogen sulfide intoxication. Handb Clin Neurol. 2015;131:111\u201333.","journal-title":"Handb Clin Neurol"},{"issue":"2","key":"710_CR50","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1016\/0041-008X(86)90140-7","volume":"84","author":"N Bitterman","year":"1986","unstructured":"Bitterman N, Talmi Y, Lerman A, Melamed Y, Taitelman U. The effect of hyperbaric oxygen on acute experimental sulfide poisoning in the rat. Toxicol Appl Pharmacol. 1986;84(2):325\u20138.","journal-title":"Toxicol Appl Pharmacol"},{"issue":"3","key":"710_CR51","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1080\/00039896.1976.10667212","volume":"31","author":"RP Smith","year":"1976","unstructured":"Smith RP, Kruszyna R, Kruszyna H. Management of acute sulfide poisoning. Archives of Environmental health: An International Journal. 1976;31(3):166\u20139.","journal-title":"Archives of Environmental health: An International Journal"},{"issue":"23","key":"710_CR52","doi-asserted-by":"publisher","first-page":"2247","DOI":"10.1016\/0006-2952(77)90287-8","volume":"26","author":"L Smith","year":"1977","unstructured":"Smith L, Kruszyna H, Smith RP. The effect of methemoglobin on the inhibition of cytochrome c oxidase by cyanide, sulfide or azide. Biochem Pharmacol. 1977;26(23):2247\u201350.","journal-title":"Biochem Pharmacol"}],"container-title":["Journal of Medical Toxicology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s13181-019-00710-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s13181-019-00710-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s13181-019-00710-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,17]],"date-time":"2022-09-17T09:13:11Z","timestamp":1663405991000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s13181-019-00710-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,6]]},"references-count":52,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,10]]}},"alternative-id":["710"],"URL":"https:\/\/doi.org\/10.1007\/s13181-019-00710-5","relation":{},"ISSN":["1556-9039","1937-6995"],"issn-type":[{"value":"1556-9039","type":"print"},{"value":"1937-6995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,5,6]]},"assertion":[{"value":"11 January 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 April 2019","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 April 2019","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 May 2019","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors disclose no additional conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}