{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T19:18:18Z","timestamp":1776453498964,"version":"3.51.2"},"reference-count":88,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T00:00:00Z","timestamp":1755734400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T00:00:00Z","timestamp":1755734400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Food Sci Technol"],"published-print":{"date-parts":[[2025,10]]},"DOI":"10.1007\/s13197-025-06414-9","type":"journal-article","created":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T08:53:44Z","timestamp":1755766424000},"page":"1842-1851","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A possible role for food-based citrus bioactive compounds in bridging the gap between prevalence of diabetes and the effectiveness of current treatments"],"prefix":"10.1007","volume":"62","author":[{"given":"Malkanthi","family":"Evans","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erin","family":"Lewis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anika","family":"Joseph","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Crowley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Najla","family":"Guthrie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,8,21]]},"reference":[{"issue":"4","key":"6414_CR2","doi-asserted-by":"publisher","first-page":"1133","DOI":"10.3390\/nu13041133","volume":"13","author":"HA Al-Aubaidy","year":"2021","unstructured":"Al-Aubaidy HA, Dayan A, Deseo MA, Itsiopoulos C, Jamil D, Hadi NR, Thomas CJ (2021) Twelve-Week mediterranean diet intervention increases citrus bioflavonoid levels and reduces inflammation in people with type 2 diabetes mellitus. Nutrients 13(4):1133. https:\/\/doi.org\/10.3390\/nu13041133","journal-title":"Nutrients"},{"issue":"9","key":"6414_CR3","doi-asserted-by":"publisher","first-page":"430","DOI":"10.3390\/biom9090430","volume":"9","author":"RK AL-Ishaq","year":"2019","unstructured":"AL-Ishaq RK, Abotaleb M, Kubatka P, Kajo K, B\u00fcsselberg D (2019) Flavonoids and their Anti-Diabetic effects: cellular mechanisms and effects to improve blood sugar levels. Biomolecules 9(9):430. https:\/\/doi.org\/10.3390\/biom9090430","journal-title":"Biomolecules"},{"issue":"3","key":"6414_CR1","doi-asserted-by":"publisher","first-page":"637","DOI":"10.3390\/nu5030637","volume":"5","author":"M Alam","year":"2013","unstructured":"Alam M, Kauter K, Brown L (2013) Naringin improves Diet-Induced cardiovascular dysfunction and obesity in high carbohydrate, high fat Diet-Fed rats. Nutrients 5(3):637\u2013650. https:\/\/doi.org\/10.3390\/nu5030637","journal-title":"Nutrients"},{"issue":"Supplement1","key":"6414_CR4","doi-asserted-by":"publisher","first-page":"S1","DOI":"10.2337\/dc25-SINT","volume":"48","author":"NA ElSayed","year":"2025","unstructured":"American Diabetes Association Professional Practice Committee, ElSayed NA, McCoy RG, Aleppo G, Bajaj M, Balapattabi K, Beverly EA, Early B, Bruemmer K, Callaghan D, Cusi BC, Das K, Ebekozien SR, Echouffo-Tcheugui O, Eichorst JB, Ekhlaspour B, Fleming L, Frykberg TK, Gaglia RG, Bannuru JL, R. R (2025) Introduction and methodology: standards of care in Diabetes\u20142025. Diabetes Care 48(Supplement1):S1\u2013S5. https:\/\/doi.org\/10.2337\/dc25-SINT","journal-title":"Diabetes Care"},{"issue":"4","key":"6414_CR5","doi-asserted-by":"publisher","first-page":"522","DOI":"10.1016\/j.amjcard.2019.05.035","volume":"124","author":"R Andary","year":"2019","unstructured":"Andary R, Fan W, Wong ND (2019) Control of cardiovascular risk factors among US adults with type 2 diabetes with and without cardiovascular disease. Am J Cardiol 124(4):522\u2013527. https:\/\/doi.org\/10.1016\/j.amjcard.2019.05.035","journal-title":"Am J Cardiol"},{"issue":"7","key":"6414_CR6","doi-asserted-by":"publisher","first-page":"474","DOI":"10.1016\/S2213-8587(23)00119-5","volume":"11","author":"RM Anjana","year":"2023","unstructured":"Anjana RM, Unnikrishnan R, Deepa M, Pradeepa R, Tandon N, Das AK, Joshi S, Bajaj S, Jabbar PK, Das HK, Kumar A, Dhandhania VK, Bhansali A, Rao PV, Desai A, Kalra S, Gupta A, Lakshmy R, Madhu SV, Ghosh S (2023) Metabolic non-communicable disease health report of india: the ICMR-INDIAB National cross-sectional study (ICMR-INDIAB-17). Lancet Diabetes Endocrinol 11(7):474\u2013489. https:\/\/doi.org\/10.1016\/S2213-8587(23)00119-5","journal-title":"Lancet Diabetes Endocrinol"},{"issue":"7","key":"6414_CR7","doi-asserted-by":"publisher","first-page":"e2429","DOI":"10.1210\/clinem\/dgaa234","volume":"105","author":"L Armiyaw","year":"2020","unstructured":"Armiyaw L, Sarcone C, Fosam A, Muniyappa R (2020) Increased \u03b2-Cell responsivity independent of insulin sensitivity in healthy African American adults. J Clin Endocrinol Metabolism 105(7):e2429\u2013e2438. https:\/\/doi.org\/10.1210\/clinem\/dgaa234","journal-title":"J Clin Endocrinol Metabolism"},{"key":"6414_CR8","doi-asserted-by":"publisher","unstructured":"Ashrafizadeh M, Ahmadi Z, Mohammadinejad R, Ghasemipour Afshar E (2020) Tangeretin: A mechanistic review of its Pharmacological and therapeutic effects. J Basic Clin Physiol Pharmacol 31(4). \/j\/jbcpp.2020.31.issue-4\/jbcpp-2019-0191\/jbcpp-2019-0191.xml. https:\/\/doi.org\/10.1515\/jbcpp-2019-0191","DOI":"10.1515\/jbcpp-2019-0191"},{"issue":"1","key":"6414_CR9","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1097\/MOL.0b013e32835c07fd","volume":"24","author":"JM Assini","year":"2013","unstructured":"Assini JM, Mulvihill EE, Huff MW (2013) Citrus flavonoids and lipid metabolism. Curr Opin Lipidol 24(1):34\u201340. https:\/\/doi.org\/10.1097\/MOL.0b013e32835c07fd","journal-title":"Curr Opin Lipidol"},{"issue":"19","key":"6414_CR10","doi-asserted-by":"publisher","first-page":"1548","DOI":"10.1001\/jama.279.19.1548","volume":"279","author":"JA Astin","year":"1998","unstructured":"Astin JA (1998) Why patients use alternative medicine: results of a National study. JAMA 279(19):1548. https:\/\/doi.org\/10.1001\/jama.279.19.1548","journal-title":"JAMA"},{"key":"6414_CR11","first-page":"98","volume":"12","author":"R Balaji","year":"2019","unstructured":"Balaji R, Duraisamy R, Kumar MPS (2019) Complications of diabetes mellitus: A review. Drug Invention Today 12:98\u2013103","journal-title":"Drug Invention Today"},{"issue":"10","key":"6414_CR12","doi-asserted-by":"publisher","first-page":"102849","DOI":"10.1016\/j.dsx.2023.102849","volume":"17","author":"S Bandyopadhyay","year":"2023","unstructured":"Bandyopadhyay S, Das S, Samajdar SS, Joshi SR (2023) Role of semaglutide in the treatment of nonalcoholic fatty liver disease or non-alcoholic steatohepatitis: A systematic review and meta-analysis. Diabetes Metabolic Syndrome 17(10):102849. https:\/\/doi.org\/10.1016\/j.dsx.2023.102849","journal-title":"Diabetes Metabolic Syndrome"},{"issue":"Suppl 2","key":"6414_CR13","first-page":"S36","volume":"13","author":"L Blonde","year":"2007","unstructured":"Blonde L (2007) State of diabetes care in the united States. Am J Manag Care 13(Suppl 2):S36\u201340","journal-title":"Am J Manag Care"},{"issue":"6","key":"6414_CR14","doi-asserted-by":"publisher","first-page":"591","DOI":"10.1007\/s11745-999-0403-7","volume":"34","author":"NM Borradaile","year":"1999","unstructured":"Borradaile NM, Carroll KK, Kurowska EM (1999) Regulation of HepG2 cell Apolipoprotein B metabolism by the citrus flavanones Hesperetin and naringenin. Lipids 34(6):591\u2013598. https:\/\/doi.org\/10.1007\/s11745-999-0403-7","journal-title":"Lipids"},{"issue":"11","key":"6414_CR15","doi-asserted-by":"publisher","first-page":"546","DOI":"10.1016\/j.it.2012.07.002","volume":"33","author":"B Brooks-Worrell","year":"2012","unstructured":"Brooks-Worrell B, Narla R, Palmer JP (2012) Biomarkers and immune-modulating therapies for type 2 diabetes. Trends Immunol 33(11):546\u2013553. https:\/\/doi.org\/10.1016\/j.it.2012.07.002","journal-title":"Trends Immunol"},{"issue":"9","key":"6414_CR16","doi-asserted-by":"publisher","first-page":"1714","DOI":"10.1194\/jlr.M087387","volume":"59","author":"AC Burke","year":"2018","unstructured":"Burke AC, Sutherland BG, Telford DE, Morrow MR, Sawyez CG, Edwards JY, Drangova M, Huff MW (2018) Intervention with citrus flavonoids reverses obesity and improves metabolic syndrome and atherosclerosis in obese Ldlr\u2013\/\u2013 mice. J Lipid Res 59(9):1714\u20131728. https:\/\/doi.org\/10.1194\/jlr.M087387","journal-title":"J Lipid Res"},{"issue":"6","key":"6414_CR17","doi-asserted-by":"publisher","first-page":"791","DOI":"10.1111\/j.1742-1241.2009.02292.x","volume":"64","author":"IW Campbell","year":"2010","unstructured":"Campbell IW (2010) Comparing the actions of older and newer therapies on body weight: to what extent should these effects guide the selection of antidiabetic therapy? Int J Clin Pract 64(6):791\u2013801. https:\/\/doi.org\/10.1111\/j.1742-1241.2009.02292.x","journal-title":"Int J Clin Pract"},{"issue":"11","key":"6414_CR18","doi-asserted-by":"publisher","first-page":"1050","DOI":"10.1089\/jmf.2021.0181","volume":"25","author":"TB Cesar","year":"2022","unstructured":"Cesar TB, Ramos FMM, Ribeiro CB (2022) Nutraceutical eriocitrin (Eriomin) reduces hyperglycemia by increasing Glucagon-Like peptide 1 and downregulates systemic inflammation: A Crossover-Randomized clinical trial. J Med Food 25(11):1050\u20131058. https:\/\/doi.org\/10.1089\/jmf.2021.0181","journal-title":"J Med Food"},{"issue":"1","key":"6414_CR19","doi-asserted-by":"publisher","first-page":"E7","DOI":"10.1152\/ajpendo.00366.2002","volume":"284","author":"AM Chang","year":"2003","unstructured":"Chang AM, Halter JB (2003) Aging and insulin secretion. Am J Physiology-Endocrinology Metabolism 284(1):E7\u2013E12. https:\/\/doi.org\/10.1152\/ajpendo.00366.2002","journal-title":"Am J Physiology-Endocrinology Metabolism"},{"issue":"4","key":"6414_CR20","doi-asserted-by":"publisher","first-page":"480","DOI":"10.1111\/jdi.12614","volume":"8","author":"C Chen","year":"2017","unstructured":"Chen C, Yang Y, Yu X, Hu S, Shao S (2017) Association between omega-3 fatty acids consumption and the risk of type 2 diabetes: A meta-analysis of cohort studies. J Diabetes Invest 8(4):480\u2013488. https:\/\/doi.org\/10.1111\/jdi.12614","journal-title":"J Diabetes Invest"},{"issue":"7","key":"6414_CR21","doi-asserted-by":"publisher","first-page":"886","DOI":"10.1161\/CIRCRESAHA.118.312806","volume":"123","author":"CW Chia","year":"2018","unstructured":"Chia CW, Egan JM, Ferrucci L (2018) Age-Related changes in glucose metabolism, hyperglycemia, and cardiovascular risk. Circul Res 123(7):886\u2013904. https:\/\/doi.org\/10.1161\/CIRCRESAHA.118.312806","journal-title":"Circul Res"},{"issue":"8","key":"6414_CR22","doi-asserted-by":"publisher","first-page":"1741","DOI":"10.2337\/dc10-2300","volume":"34","author":"M Chiu","year":"2011","unstructured":"Chiu M, Austin PC, Manuel DG, Shah BR, Tu JV (2011) Deriving Ethnic-Specific BMI cutoff points for assessing diabetes risk. Diabetes Care 34(8):1741\u20131748. https:\/\/doi.org\/10.2337\/dc10-2300","journal-title":"Diabetes Care"},{"issue":"1","key":"6414_CR23","doi-asserted-by":"publisher","first-page":"67","DOI":"10.2337\/ds19-0068","volume":"34","author":"LV Cross","year":"2021","unstructured":"Cross LV, Thomas JR (2021) Safety and efficacy of dietary supplements for diabetes. Diabetes Spectr 34(1):67\u201372. https:\/\/doi.org\/10.2337\/ds19-0068","journal-title":"Diabetes Spectr"},{"issue":"4","key":"6414_CR24","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1111\/j.1755-5922.2010.00179.x","volume":"28","author":"G Dav\u00ec","year":"2010","unstructured":"Dav\u00ec G, Santilli F, Patrono C (2010) Nutraceuticals in diabetes and metabolic syndrome. Cardiovasc Ther 28(4):216\u2013226. https:\/\/doi.org\/10.1111\/j.1755-5922.2010.00179.x","journal-title":"Cardiovasc Ther"},{"issue":"2","key":"6414_CR25","doi-asserted-by":"publisher","first-page":"324","DOI":"10.2337\/diacare.25.2.324","volume":"25","author":"LE Egede","year":"2002","unstructured":"Egede LE, Ye X, Zheng D, Silverstein MD (2002) The prevalence and pattern of complementary and alternative medicine use in individuals with diabetes. Diabetes Care 25(2):324\u2013329. https:\/\/doi.org\/10.2337\/diacare.25.2.324","journal-title":"Diabetes Care"},{"issue":"4","key":"6414_CR26","first-page":"265","volume":"10","author":"BC Eliason","year":"1997","unstructured":"Eliason BC, Kruger J, Mark D, Rasmann DN (1997) Dietary supplement users: demographics, product use, and medical system interaction. J Am Board Family Pract 10(4):265\u2013271","journal-title":"J Am Board Family Pract"},{"key":"6414_CR27","doi-asserted-by":"publisher","first-page":"275","DOI":"10.2147\/DMSO.S79450","volume":"8","author":"M Evans","year":"2015","unstructured":"Evans M, Judy WV, Wilson D, Rumberger JA, Guthrie N (2015) Randomized, double-blind, placebo-controlled, clinical study on the effect of Diabetinol(\u00ae) on glycemic control of subjects with impaired fasting glucose. Diabetes Metabolic Syndrome Obesity: Targets Therapy 8:275\u2013286. https:\/\/doi.org\/10.2147\/DMSO.S79450","journal-title":"Diabetes Metabolic Syndrome Obesity: Targets Therapy"},{"issue":"3","key":"6414_CR28","doi-asserted-by":"publisher","first-page":"e001410","DOI":"10.1136\/bmjgh-2019-001410","volume":"4","author":"M Ewen","year":"2019","unstructured":"Ewen M, Joosse H-J, Beran D, Laing R (2019) Insulin prices, availability and affordability in 13 low-income and middle-income countries. BMJ Global Health 4(3):e001410. https:\/\/doi.org\/10.1136\/bmjgh-2019-001410","journal-title":"BMJ Global Health"},{"issue":"5","key":"6414_CR29","doi-asserted-by":"publisher","first-page":"842","DOI":"10.1016\/j.ctim.2014.08.004","volume":"22","author":"Z Fang","year":"2014","unstructured":"Fang Z, Zhao J, Shi G, Shu Y, Ni Y, Wang H, Ding L, Lu R, Li J, Zhu X, Cheng S, Zhang X, Liu Y, Wang J, Luo Y, Fan Q, Guo C, Jiang T, Wu Q, Anderson RM (2014) Shenzhu Tiaopi granule combined with lifestyle intervention therapy for impaired glucose tolerance: A randomized controlled trial. Complement Ther Med 22(5):842\u2013850. https:\/\/doi.org\/10.1016\/j.ctim.2014.08.004","journal-title":"Complement Ther Med"},{"issue":"8","key":"6414_CR30","doi-asserted-by":"publisher","first-page":"1948","DOI":"10.2337\/dc19-2419","volume":"43","author":"S Gan","year":"2020","unstructured":"Gan S, Dawed AY, Donnelly LA, Nair ATN, Palmer CNA, Mohan V, Pearson ER (2020) Efficacy of modern diabetes treatments DPP-4i, SGLT-2i, and GLP-1RA in white and Asian patients with diabetes: A systematic review and Meta-analysis of randomized controlled trials. Diabetes Care 43(8):1948\u20131957. https:\/\/doi.org\/10.2337\/dc19-2419","journal-title":"Diabetes Care"},{"issue":"10","key":"6414_CR31","doi-asserted-by":"publisher","first-page":"2907","DOI":"10.3390\/nu12102907","volume":"12","author":"GR Gandhi","year":"2020","unstructured":"Gandhi GR, Vasconcelos ABS, Wu D-T, Li H-B, Antony PJ, Li H, Geng F, Gurgel RQ, Narain N, Gan R-Y (2020) Citrus flavonoids as promising phytochemicals targeting diabetes and related complications: A systematic review of in vitro and. Vivo Stud Nutrients 12(10):2907. https:\/\/doi.org\/10.3390\/nu12102907","journal-title":"Vivo Stud Nutrients"},{"issue":"1","key":"6414_CR32","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/j.jdiacomp.2013.10.002","volume":"28","author":"UP Gujral","year":"2014","unstructured":"Gujral UP, Narayan KMV, Kahn SE, Kanaya AM (2014) The relative associations of \u03b2-cell function and insulin sensitivity with glycemic status and incident glycemic progression in migrant Asian Indians in the united states: the MASALA study. J Diabetes Complicat 28(1):45\u201350. https:\/\/doi.org\/10.1016\/j.jdiacomp.2013.10.002","journal-title":"J Diabetes Complicat"},{"key":"6414_CR33","doi-asserted-by":"publisher","unstructured":"Gulati K, Wijndaele K, Webb J, Von Arx L, Seif M, Jennison T, Geneidat A, Wild R, Wood R, Khunti K (2025) Achievement of HbA1c and weight targets in adults with type 2 diabetes on once weekly injectable glucagon-like peptide\u20101 receptor agonist therapy in UK primary care: A retrospective, real\u2010world study. Diabetes Obes Metabolism dom16201. https:\/\/doi.org\/10.1111\/dom.16201","DOI":"10.1111\/dom.16201"},{"issue":"8","key":"6414_CR34","doi-asserted-by":"publisher","first-page":"1791","DOI":"10.2337\/dc11-0088","volume":"34","author":"LS Gupta","year":"2011","unstructured":"Gupta LS, Wu CC, Young S, Perlman SE (2011) Prevalence of diabetes in new York city, 2002\u20132008. Diabetes Care 34(8):1791\u20131793. https:\/\/doi.org\/10.2337\/dc11-0088","journal-title":"Diabetes Care"},{"issue":"4","key":"6414_CR35","doi-asserted-by":"publisher","first-page":"427","DOI":"10.2337\/cd21-0004","volume":"39","author":"JR Herges","year":"2021","unstructured":"Herges JR, Neumiller JJ, McCoy RG (2021) Easing the financial burden of diabetes management: A guide for patients and primary care clinicians. Clin Diabetes: Publication Am Diabetes Association 39(4):427\u2013436. https:\/\/doi.org\/10.2337\/cd21-0004","journal-title":"Clin Diabetes: Publication Am Diabetes Association"},{"key":"6414_CR36","unstructured":"International Diabetes Federation (2022) Facts & figures. Dataset. https:\/\/idf.org\/about-diabetes\/diabetes-facts-figures\/"},{"issue":"8","key":"6414_CR37","doi-asserted-by":"publisher","first-page":"1376","DOI":"10.1177\/0898264318780023","volume":"31","author":"PJ Johnson","year":"2019","unstructured":"Johnson PJ, Jou J, Rockwood TH, Upchurch DM (2019) Perceived benefits of using complementary and alternative medicine by race\/ethnicity among midlife and older adults in the united States. J Aging Health 31(8):1376\u20131397. https:\/\/doi.org\/10.1177\/0898264318780023","journal-title":"J Aging Health"},{"issue":"3","key":"6414_CR38","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1016\/j.jff.2010.04.005","volume":"2","author":"W Judy","year":"2010","unstructured":"Judy W, Stogsdill W, Judy D, Judy J, Sharma P, Evans M, Guthrie N (2010) Efficacy of Diabetinol\u2122 on glycemic control in insulin resistant hamsters and subjects with impaired fasting glucose \u2013 a pilot study. J Funct Foods 2(3):171\u2013178. https:\/\/doi.org\/10.1016\/j.jff.2010.04.005","journal-title":"J Funct Foods"},{"key":"6414_CR39","doi-asserted-by":"publisher","first-page":"110037","DOI":"10.1016\/j.diabres.2022.110037","volume":"191","author":"A Kazemi","year":"2022","unstructured":"Kazemi A, Ryul Shim S, Jamali N, Hassanzadeh-Rostami Z, Soltani S, Sasani N, Mohsenpour MA, Firoozi D, Basirat R, Hosseini R, Clark CCT, Babajafari S, Soltanmohammadi M (2022) Comparison of nutritional supplements for glycemic control in type 2 diabetes: A systematic review and network meta-analysis of randomized trials. Diabetes Res Clin Pract 191:110037. https:\/\/doi.org\/10.1016\/j.diabres.2022.110037","journal-title":"Diabetes Res Clin Pract"},{"key":"6414_CR40","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1016\/j.diabres.2017.12.004","volume":"137","author":"K Khunti","year":"2018","unstructured":"Khunti K, Ceriello A, Cos X, De Block C (2018) Achievement of guideline targets for blood pressure, lipid, and glycaemic control in type 2 diabetes: A meta-analysis. Diabetes Res Clin Pract 137:137\u2013148. https:\/\/doi.org\/10.1016\/j.diabres.2017.12.004","journal-title":"Diabetes Res Clin Pract"},{"issue":"4","key":"6414_CR41","doi-asserted-by":"publisher","first-page":"456","DOI":"10.1016\/j.neuropharm.2009.06.013","volume":"57","author":"A Kuhad","year":"2009","unstructured":"Kuhad A, Chopra K (2009) Tocotrienol attenuates oxidative\u2013nitrosative stress and inflammatory cascade in experimental model of diabetic neuropathy. Neuropharmacology 57(4):456\u2013462. https:\/\/doi.org\/10.1016\/j.neuropharm.2009.06.013","journal-title":"Neuropharmacology"},{"issue":"8","key":"6414_CR42","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1016\/j.puhe.2006.04.010","volume":"120","author":"D Kumar","year":"2006","unstructured":"Kumar D, Bajaj S, Mehrotra R (2006) Knowledge, attitude and practice of complementary and alternative medicines for diabetes. Public Health 120(8):705\u2013711. https:\/\/doi.org\/10.1016\/j.puhe.2006.04.010","journal-title":"Public Health"},{"key":"6414_CR43","doi-asserted-by":"publisher","unstructured":"Kurowska EM (2001) Determination of cholesterol-lowering potential of minor dietary components by measuring apolipoprotein B responses in HepG2 cells. In Methods in Enzymology (Vol. 335, pp. 398\u2013404). Elsevier. https:\/\/doi.org\/10.1016\/S0076-6879(01)35262-X","DOI":"10.1016\/S0076-6879(01)35262-X"},{"key":"6414_CR44","doi-asserted-by":"publisher","unstructured":"Kurowska EM, Manthey JA (2002) Regulation of Lipoprotein Metabolism in HepG2 Cells by Citrus Flavonoids. In B. S. Buslig & J. A. Manthey (Eds.), Flavonoids in Cell Function (Vol. 505, pp. 173\u2013179). Springer US. https:\/\/doi.org\/10.1007\/978-1-4757-5235-9_16","DOI":"10.1007\/978-1-4757-5235-9_16"},{"issue":"10","key":"6414_CR45","doi-asserted-by":"publisher","first-page":"2879","DOI":"10.1021\/jf035354z","volume":"52","author":"EM Kurowska","year":"2004","unstructured":"Kurowska EM, Manthey JA (2004) Hypolipidemic effects and absorption of citrus polymethoxylated flavones in hamsters with Diet-Induced hypercholesterolemia. J Agric Food Chem 52(10):2879\u20132886. https:\/\/doi.org\/10.1021\/jf035354z","journal-title":"J Agric Food Chem"},{"issue":"2","key":"6414_CR46","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1111\/j.1467-3010.2011.01889.x","volume":"36","author":"G Leung","year":"2011","unstructured":"Leung G, Stanner S (2011) Diets of minority ethnic groups in the UK: influence on chronic disease risk and implications for prevention: diets of minority ethnic groups in the UK. Nutr Bull 36(2):161\u2013198. https:\/\/doi.org\/10.1111\/j.1467-3010.2011.01889.x","journal-title":"Nutr Bull"},{"key":"6414_CR47","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2019\/5484138","volume":"2019","author":"AM Mahmoud","year":"2019","unstructured":"Mahmoud AM, Hern\u00e1ndez Bautista RJ, Sandhu MA, Hussein OE (2019) Beneficial effects of citrus flavonoids on cardiovascular and metabolic health. Oxidative Med Cell Longev 2019:1\u201319. https:\/\/doi.org\/10.1155\/2019\/5484138","journal-title":"Oxidative Med Cell Longev"},{"issue":"1","key":"6414_CR48","doi-asserted-by":"publisher","first-page":"2971","DOI":"10.1038\/s41598-023-29978-y","volume":"13","author":"S Maiti","year":"2023","unstructured":"Maiti S, Akhtar S, Upadhyay AK, Mohanty SK (2023) Socioeconomic inequality in awareness, treatment and control of diabetes among adults in india: evidence from National family health survey of India (NFHS), 2019\u20132021. Sci Rep 13(1):2971. https:\/\/doi.org\/10.1038\/s41598-023-29978-y","journal-title":"Sci Rep"},{"issue":"6","key":"6414_CR49","doi-asserted-by":"publisher","first-page":"1474","DOI":"10.3390\/cells10061474","volume":"10","author":"M\u00c1 Mart\u00edn","year":"2021","unstructured":"Mart\u00edn M\u00c1, Ramos S (2021) Dietary flavonoids and insulin signaling in diabetes and obesity. Cells 10(6):1474. https:\/\/doi.org\/10.3390\/cells10061474","journal-title":"Cells"},{"issue":"18","key":"6414_CR50","doi-asserted-by":"publisher","first-page":"3413","DOI":"10.3390\/foods12183413","volume":"12","author":"M Maurer Sost","year":"2023","unstructured":"Maurer Sost M, Stevens Y, Salden B, Troost F, Masclee A, Venema K (2023) Citrus extract high in flavonoids beneficially alters intestinal metabolic responses in subjects with features of metabolic syndrome. Foods 12(18):3413. https:\/\/doi.org\/10.3390\/foods12183413","journal-title":"Foods"},{"issue":"2","key":"6414_CR51","doi-asserted-by":"publisher","first-page":"454","DOI":"10.3945\/ajcn.111.016634","volume":"95","author":"ML McCullough","year":"2012","unstructured":"McCullough ML, Peterson JJ, Patel R, Jacques PF, Shah R, Dwyer JT (2012) Flavonoid intake and cardiovascular disease mortality in a prospective cohort of US adults. Am J Clin Nutr 95(2):454\u2013464. https:\/\/doi.org\/10.3945\/ajcn.111.016634","journal-title":"Am J Clin Nutr"},{"issue":"9","key":"6414_CR52","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1016\/S2213-8587(24)00182-7","volume":"12","author":"BM McGowan","year":"2024","unstructured":"McGowan BM, Bruun JM, Capehorn M, Pedersen SD, Pietil\u00e4inen KH, Muniraju HAK, Quiroga M, Varbo A, Lau DCW (2024) Efficacy and safety of once-weekly semaglutide 2\u00b74\u00a0mg versus placebo in people with obesity and prediabetes (STEP 10): A randomised, double-blind, placebo-controlled, multicentre phase 3 trial. Lancet Diabetes Endocrinol 12(9):631\u2013642. https:\/\/doi.org\/10.1016\/S2213-8587(24)00182-7","journal-title":"Lancet Diabetes Endocrinol"},{"issue":"5","key":"6414_CR53","doi-asserted-by":"publisher","first-page":"417","DOI":"10.4158\/EP.9.5.417","volume":"9","author":"JI Mechanick","year":"2003","unstructured":"Mechanick JI, Brett EM, Chausmer AB, Dickey RA, Wallach S, American Association of Clinical Endocrinologists (2003) American association of clinical endocrinologists medical guidelines for the clinical use of dietary supplements and nutraceuticals. Endocr Practice: Official J Am Coll Endocrinol Am Association Clin Endocrinologists 9(5):417\u2013470. https:\/\/doi.org\/10.4158\/EP.9.5.417","journal-title":"Endocr Practice: Official J Am Coll Endocrinol Am Association Clin Endocrinologists"},{"issue":"1","key":"6414_CR54","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1186\/1475-2891-13-102","volume":"13","author":"AB Medagama","year":"2014","unstructured":"Medagama AB, Bandara R (2014) The use of complementary and alternative medicines (CAMs) in the treatment of diabetes mellitus: is continued use safe and effective? Nutr J 13(1):102. https:\/\/doi.org\/10.1186\/1475-2891-13-102","journal-title":"Nutr J"},{"issue":"7","key":"6414_CR55","doi-asserted-by":"publisher","first-page":"2708","DOI":"10.3390\/nu5072708","volume":"5","author":"A Misra","year":"2013","unstructured":"Misra A, Shrivastava U (2013) Obesity and dyslipidemia in South Asians. Nutrients 5(7):2708\u20132733. https:\/\/doi.org\/10.3390\/nu5072708","journal-title":"Nutrients"},{"key":"6414_CR56","doi-asserted-by":"publisher","unstructured":"Misra A, Vikram NK, Ghosh A, Ranjan P, Gulati S (2025) Revised definition of obesity in Asian Indians living in India. Diabetes Metabolic Syndrome: Clin Res Reviews 102989. https:\/\/doi.org\/10.1016\/j.dsx.2024.102989","DOI":"10.1016\/j.dsx.2024.102989"},{"issue":"1","key":"6414_CR57","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1016\/j.ecl.2013.09.010","volume":"43","author":"J Mitri","year":"2014","unstructured":"Mitri J, Pittas AG (2014) Vitamin D and diabetes. Endocrinol Metab Clin North Am 43(1):205\u2013232. https:\/\/doi.org\/10.1016\/j.ecl.2013.09.010","journal-title":"Endocrinol Metab Clin North Am"},{"key":"6414_CR58","unstructured":"Morse A (2023), November 9 Global Population Estimates Vary but Trends Are Clear: Population Growth Is Slowing. https:\/\/www.census.gov\/library\/stories\/2023\/11\/world-population-estimated-eight-billion.html#:~:text=Population%20Division%20estimates%20the%20world,it%20was%20in%20the%20past"},{"issue":"1","key":"6414_CR59","doi-asserted-by":"publisher","first-page":"E1","DOI":"10.1503\/cmaj.220673","volume":"195","author":"S Nandiwada","year":"2023","unstructured":"Nandiwada S, Manca DP, Yeung RO, Lau D (2023) Achievement of treatment targets among patients with type 2 diabetes in 2015 and 2020 in Canadian primary care. Can Med Assoc J 195(1):E1\u2013E9. https:\/\/doi.org\/10.1503\/cmaj.220673","journal-title":"Can Med Assoc J"},{"issue":"1","key":"6414_CR60","doi-asserted-by":"publisher","first-page":"e001927","DOI":"10.1136\/bmjdrc-2020-001927","volume":"9","author":"KMV Narayan","year":"2021","unstructured":"Narayan KMV, Kondal D, Daya N, Gujral UP, Mohan D, Patel SA, Shivashankar R, Anjana RM, Staimez LR, Ali MK, Chang HH, Kadir M, Prabhakaran D, Selvin E, Mohan V, Tandon N (2021) Incidence and pathophysiology of diabetes in South Asian adults living in India and Pakistan compared with US Blacks and Whites. BMJ Open Diabetes Res Care 9(1):e001927. https:\/\/doi.org\/10.1136\/bmjdrc-2020-001927","journal-title":"BMJ Open Diabetes Res Care"},{"issue":"22","key":"6414_CR61","doi-asserted-by":"publisher","first-page":"7727","DOI":"10.3390\/molecules27227727","volume":"27","author":"GNN Neba Ambe","year":"2022","unstructured":"Neba Ambe GNN, Breda C, Bhambra AS, Arroo RRJ (2022) Effect of the citrus flavone nobiletin on circadian rhythms and metabolic syndrome. Molecules 27(22):7727. https:\/\/doi.org\/10.3390\/molecules27227727","journal-title":"Molecules"},{"issue":"1","key":"6414_CR62","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1186\/s12902-024-01658-6","volume":"24","author":"Y Oe","year":"2024","unstructured":"Oe Y, Nomoto H, Cho KY, Yokozeki K, Ono T, Miya A, Kameda H, Nakamura A, Arimura Y, Atsumi T (2024) Efficacy and safety of oral semaglutide in older patients with type 2 diabetes: A retrospective observational study (the OTARU-SEMA study). BMC Endocr Disorders 24(1):124. https:\/\/doi.org\/10.1186\/s12902-024-01658-6","journal-title":"BMC Endocr Disorders"},{"key":"6414_CR63","doi-asserted-by":"publisher","first-page":"7","DOI":"10.20517\/ch.2021.03","volume":"1","author":"S Omboni","year":"2022","unstructured":"Omboni S, Padwal RS, Alessa T, Bencz\u00far B, Green BB, Hubbard I, Kario K, Khan NA, Konradi A, Logan AG, Lu Y, Mars M, McManus RJ, Melville S, Neumann CL, Parati G, Renna NF, Ryvlin P, Saner H, Wang J (2022) The worldwide impact of telemedicine during COVID-19: current evidence and recommendations for the future. Connected Health 1:7\u201335. https:\/\/doi.org\/10.20517\/ch.2021.03","journal-title":"Connected Health"},{"issue":"3","key":"6414_CR64","doi-asserted-by":"publisher","first-page":"677","DOI":"10.1016\/j.bbrc.2011.06.055","volume":"410","author":"E Ono","year":"2011","unstructured":"Ono E, Inoue J, Hashidume T, Shimizu M, Sato R (2011) Anti-obesity and anti-hyperglycemic effects of the dietary citrus limonoid nomilin in mice fed a high-fat diet. Biochem Biophys Res Commun 410(3):677\u2013681. https:\/\/doi.org\/10.1016\/j.bbrc.2011.06.055","journal-title":"Biochem Biophys Res Commun"},{"issue":"4","key":"6414_CR65","doi-asserted-by":"publisher","first-page":"661","DOI":"10.2105\/AJPH.2008.149492","volume":"100","author":"R Oza-Frank","year":"2010","unstructured":"Oza-Frank R, Narayan KMV (2010) Overweight and diabetes prevalence among US immigrants. Am J Public Health 100(4):661\u2013668. https:\/\/doi.org\/10.2105\/AJPH.2008.149492","journal-title":"Am J Public Health"},{"issue":"2","key":"6414_CR66","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1016\/j.jnutbio.2011.12.009","volume":"24","author":"H-J Park","year":"2013","unstructured":"Park H-J, Jung UJ, Cho S-J, Jung H-K, Shim S, Choi M-S (2013) Citrus Unshiu Peel extract ameliorates hyperglycemia and hepatic steatosis by altering inflammation and hepatic glucose- and lipid-regulating enzymes in db\/db mice. J Nutr Biochem 24(2):419\u2013427. https:\/\/doi.org\/10.1016\/j.jnutbio.2011.12.009","journal-title":"J Nutr Biochem"},{"issue":"11","key":"6414_CR67","doi-asserted-by":"publisher","first-page":"2932","DOI":"10.4103\/ijo.IJO_1627_21","volume":"69","author":"R Pradeepa","year":"2021","unstructured":"Pradeepa R, Mohan V (2021) Epidemiology of type 2 diabetes in India. Indian J Ophthalmol 69(11):2932\u20132938. https:\/\/doi.org\/10.4103\/ijo.IJO_1627_21","journal-title":"Indian J Ophthalmol"},{"issue":"3","key":"6414_CR68","doi-asserted-by":"publisher","first-page":"263","DOI":"10.3803\/EnM.2015.30.3.263","volume":"30","author":"E-J Rhee","year":"2015","unstructured":"Rhee E-J (2015) Diabetes in Asians. Endocrinol Metabolism 30(3):263. https:\/\/doi.org\/10.3803\/EnM.2015.30.3.263","journal-title":"Endocrinol Metabolism"},{"issue":"3","key":"6414_CR69","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1016\/S2213-8587(24)00316-4","volume":"13","author":"F Rubino","year":"2025","unstructured":"Rubino F, Cummings DE, Eckel RH, Cohen RV, Wilding JPH, Brown WA, Stanford FC, Batterham RL, Farooqi IS, Farpour-Lambert NJ, Le Roux CW, Sattar N, Baur LA, Morrison KM, Misra A, Kadowaki T, Tham KW, Sumithran P, Garvey WT, Mingrone G (2025) Definition and diagnostic criteria of clinical obesity. Lancet Diabetes Endocrinol 13(3):221\u2013262. https:\/\/doi.org\/10.1016\/S2213-8587(24)00316-4","journal-title":"Lancet Diabetes Endocrinol"},{"issue":"5","key":"6414_CR70","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1016\/j.eprac.2023.02.001","volume":"29","author":"SL Samson","year":"2023","unstructured":"Samson SL, Vellanki P, Blonde L, Christofides EA, Galindo RJ, Hirsch IB, Isaacs SD, Izuora KE, Wang L, Twining CC, Umpierrez CL, G. E., Valencia WM (2023) American association of clinical endocrinology consensus statement: comprehensive type 2 diabetes management Algorithm \u2013 2023 update. Endocr Pract 29(5):305\u2013340. https:\/\/doi.org\/10.1016\/j.eprac.2023.02.001","journal-title":"Endocr Pract"},{"issue":"5","key":"6414_CR71","doi-asserted-by":"publisher","first-page":"476","DOI":"10.1007\/s11886-014-0476-5","volume":"16","author":"A Shah","year":"2014","unstructured":"Shah A, Kanaya AM (2014) Diabetes and associated complications in the South Asian population. Curr Cardiol Rep 16(5):476. https:\/\/doi.org\/10.1007\/s11886-014-0476-5","journal-title":"Curr Cardiol Rep"},{"issue":"11","key":"6414_CR72","doi-asserted-by":"publisher","first-page":"1713","DOI":"10.1017\/S000711451100225X","volume":"106","author":"AK Sharma","year":"2011","unstructured":"Sharma AK, Bharti S, Ojha S, Bhatia J, Kumar N, Ray R, Kumari S, Arya DS (2011) Up-regulation of PPAR\u03b3, heat shock protein-27 and \u2013\u200972 by naringin attenuates insulin resistance, \u03b2-cell dysfunction, hepatic steatosis and kidney damage in a rat model of type 2 diabetes. Br J Nutr 106(11):1713\u20131723. https:\/\/doi.org\/10.1017\/S000711451100225X","journal-title":"Br J Nutr"},{"issue":"4","key":"6414_CR73","doi-asserted-by":"publisher","first-page":"4115","DOI":"10.1016\/j.foodchem.2013.06.059","volume":"141","author":"EJ Shin","year":"2013","unstructured":"Shin EJ, Hur HJ, Sung MJ, Park JH, Yang HJ, Kim MS, Kwon DY, Hwang J-T (2013) Ethanol extract of the Prunus Mume fruits stimulates glucose uptake by regulating PPAR-\u03b3 in C2C12 myotubes and ameliorates glucose intolerance and fat accumulation in mice fed a high-fat diet. Food Chem 141(4):4115\u20134121. https:\/\/doi.org\/10.1016\/j.foodchem.2013.06.059","journal-title":"Food Chem"},{"issue":"1","key":"6414_CR74","doi-asserted-by":"publisher","first-page":"187","DOI":"10.2337\/dc08-9026","volume":"32","author":"JS Skyler","year":"2009","unstructured":"Skyler JS, Bergenstal R, Bonow RO, Buse J, Deedwania P, Gale EAM, Howard BV, Kirkman MS, Kosiborod M, Reaven P, Sherwin RS, American Diabetes Association, American College of Cardiology Foundation, & American Heart Association (2009) Intensive glycemic control and the prevention of cardiovascular events: implications of the ACCORD, ADVANCE, and VA diabetes trials: a position statement of the American diabetes association and a scientific statement of the American college of cardiology foundation and the American heart association. Diabetes Care 32(1):187\u2013192. https:\/\/doi.org\/10.2337\/dc08-9026","journal-title":"Diabetes Care"},{"issue":"6","key":"6414_CR75","doi-asserted-by":"publisher","first-page":"426","DOI":"10.1007\/BF03405030","volume":"93","author":"L Troppmann","year":"2002","unstructured":"Troppmann L, Johns T, Gray-Donald K (2002) Natural health product use in Canada. Can J Public Health = Revue Canadienne De Sante Publique 93(6):426\u2013430. https:\/\/doi.org\/10.1007\/BF03405030","journal-title":"Can J Public Health = Revue Canadienne De Sante Publique"},{"issue":"1","key":"6414_CR76","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1001\/jamapediatrics.2015.2757","volume":"170","author":"U Uusitalo","year":"2016","unstructured":"Uusitalo U, Liu X, Yang J, Aronsson CA, Hummel S, Butterworth M, Lernmark \u00c5, Rewers M, Hagopian W, She J-X, Simell O, Toppari J, Ziegler AG, Akolkar B, Krischer J, Norris JM, Virtanen SM, TEDDY Study Group (2016) Association of early exposure of probiotics and islet autoimmunity in the TEDDY study. JAMA Pediatr 170(1):20\u201328. https:\/\/doi.org\/10.1001\/jamapediatrics.2015.2757","journal-title":"JAMA Pediatr"},{"issue":"9344","key":"6414_CR77","doi-asserted-by":"publisher","first-page":"1477","DOI":"10.1016\/S0140-6736(02)11436-X","volume":"360","author":"RM van Dam","year":"2002","unstructured":"van Dam RM, Feskens EJM (2002) Coffee consumption and risk of type 2 diabetes mellitus. Lancet (London England) 360(9344):1477\u20131478. https:\/\/doi.org\/10.1016\/S0140-6736(02)11436-X","journal-title":"Lancet (London England)"},{"issue":"9","key":"6414_CR78","doi-asserted-by":"publisher","first-page":"963","DOI":"10.1001\/jamainternmed.2023.3070","volume":"183","author":"JS Varghese","year":"2023","unstructured":"Varghese JS, Anjana RM, Geldsetzer P, Sudharsanan N, Manne-Goehler J, Thirumurthy H, Bhattacharyya S, Narayan KMV, Mohan V, Tandon N, Ali MK (2023) National estimates of the adult diabetes care continuum in india, 2019\u20132021. JAMA Intern Med 183(9):963. https:\/\/doi.org\/10.1001\/jamainternmed.2023.3070","journal-title":"JAMA Intern Med"},{"issue":"3\u20134","key":"6414_CR79","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1177\/0972753120987465","volume":"27","author":"M Venkatrao","year":"2020","unstructured":"Venkatrao M, Nagarathna R, Majumdar V, Patil SS, Rathi S, Nagendra H (2020) Prevalence of obesity in India and its neurological implications: A multifactor analysis of a nationwide Cross-Sectional study. Annals Neurosciences 27(3\u20134):153\u2013161. https:\/\/doi.org\/10.1177\/0972753120987465","journal-title":"Annals Neurosciences"},{"issue":"7","key":"6414_CR80","doi-asserted-by":"publisher","first-page":"1009","DOI":"10.1001\/archinte.160.7.1009","volume":"160","author":"V Vuksan","year":"2000","unstructured":"Vuksan V, Sievenpiper JL, Koo VY, Francis T, Beljan-Zdravkovic U, Xu Z, Vidgen E (2000) American ginseng (Panax Quinquefolius L) reduces postprandial glycemia in nondiabetic subjects and subjects with type 2 diabetes mellitus. Arch Intern Med 160(7):1009\u20131013. https:\/\/doi.org\/10.1001\/archinte.160.7.1009","journal-title":"Arch Intern Med"},{"issue":"4","key":"6414_CR81","doi-asserted-by":"publisher","first-page":"753","DOI":"10.1093\/ajcn\/73.4.753","volume":"73","author":"V Vuksan","year":"2001","unstructured":"Vuksan V, Sievenpiper JL, Wong J, Xu Z, Beljan-Zdravkovic U, Arnason JT, Assinewe V, Stavro MP, Jenkins AL, Leiter LA, Francis T (2001) American ginseng (Panax Quinquefolius L.) attenuates postprandial glycemia in a time-dependent but not dose-dependent manner in healthy individuals. Am J Clin Nutr 73(4):753\u2013758. https:\/\/doi.org\/10.1093\/ajcn\/73.4.753","journal-title":"Am J Clin Nutr"},{"issue":"10397","key":"6414_CR82","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1016\/S0140-6736(23)00914-5","volume":"402","author":"AF Walker","year":"2023","unstructured":"Walker AF, Graham S, Maple-Brown L, Egede LE, Campbell JA, Walker RJ, Wade AN, Mbanya JC, Long JA, Yajnik C, Thomas N, Ebekozien O, Odugbesan O, DiMeglio LA, Agarwal S (2023) Interventions to address global inequity in diabetes: international progress. Lancet 402(10397):250\u2013264. https:\/\/doi.org\/10.1016\/S0140-6736(23)00914-5","journal-title":"Lancet"},{"key":"6414_CR83","unstructured":"WHO (2022) First-ever global coverage targets for diabetes adopted at the 75th World Health Assembly. https:\/\/www.who.int\/news-room\/feature-stories\/detail\/first-ever-global-coverage-targets-for-diabetes-adopted-at-the-75-th-world-health-assembly#:~:text=28%20May%202022,requested%20the%20WHO%20Secretariat%20to"},{"issue":"10","key":"6414_CR84","doi-asserted-by":"publisher","first-page":"1527","DOI":"10.3390\/nu4101527","volume":"4","author":"W-Y Wong","year":"2012","unstructured":"Wong W-Y, Poudyal H, Ward LC, Brown L (2012) Tocotrienols reverse cardiovascular, metabolic and liver changes in high carbohydrate, high fat Diet-Fed rats. Nutrients 4(10):1527\u20131541. https:\/\/doi.org\/10.3390\/nu4101527","journal-title":"Nutrients"},{"issue":"19","key":"6414_CR85","doi-asserted-by":"publisher","first-page":"e0686","DOI":"10.1097\/MD.0000000000010686","volume":"97","author":"H Xu","year":"2018","unstructured":"Xu H, Luo J, Huang J, Wen Q (2018) Flavonoids intake and risk of type 2 diabetes mellitus: A meta-analysis of prospective cohort studies. Medicine 97(19):e0686. https:\/\/doi.org\/10.1097\/MD.0000000000010686","journal-title":"Medicine"},{"issue":"10","key":"6414_CR86","doi-asserted-by":"publisher","first-page":"1648","DOI":"10.2105\/ajph.92.10.1648","volume":"92","author":"GY Yeh","year":"2002","unstructured":"Yeh GY, Eisenberg DM, Davis RB, Phillips RS (2002) Use of complementary and alternative medicine among persons with diabetes mellitus: results of a National survey. Am J Public Health 92(10):1648\u20131652. https:\/\/doi.org\/10.2105\/ajph.92.10.1648","journal-title":"Am J Public Health"},{"key":"6414_CR87","doi-asserted-by":"publisher","first-page":"1192131","DOI":"10.3389\/fnut.2023.1192131","volume":"10","author":"X Yi","year":"2023","unstructured":"Yi X, Dong M, Guo N, Tian J, Lei P, Wang S, Yang Y, Shi Y (2023) Flavonoids improve type 2 diabetes mellitus and its complications: A review. Front Nutr 10:1192131. https:\/\/doi.org\/10.3389\/fnut.2023.1192131","journal-title":"Front Nutr"},{"key":"6414_CR88","doi-asserted-by":"publisher","first-page":"1149239","DOI":"10.3389\/fendo.2023.1149239","volume":"14","author":"X Zhao","year":"2023","unstructured":"Zhao X, An X, Yang C, Sun W, Ji H, Lian F (2023) The crucial role and mechanism of insulin resistance in metabolic disease. Front Endocrinol 14:1149239. https:\/\/doi.org\/10.3389\/fendo.2023.1149239","journal-title":"Front Endocrinol"}],"container-title":["Journal of Food Science and Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13197-025-06414-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s13197-025-06414-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13197-025-06414-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T09:18:05Z","timestamp":1756977485000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s13197-025-06414-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,21]]},"references-count":88,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["6414"],"URL":"https:\/\/doi.org\/10.1007\/s13197-025-06414-9","relation":{},"ISSN":["0022-1155","0975-8402"],"issn-type":[{"value":"0022-1155","type":"print"},{"value":"0975-8402","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,21]]},"assertion":[{"value":"20 December 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 June 2025","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 June 2025","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 August 2025","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no conflicts of interest or competing interests that could influence the objectivity or the impartiality of the work.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Not applicable.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}}]}}