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Based on the morphology and 16S rDNA sequence, the isolated myxobacteria were identified as <jats:italic>Corallococcus<\/jats:italic> sp., <jats:italic>Pyxidicoccus<\/jats:italic> sp., <jats:italic>Myxococcus<\/jats:italic> sp., <jats:italic>Cystobacter<\/jats:italic> sp. and <jats:italic>Archangium<\/jats:italic> sp. The myxobacteria were functionally characterized to assess their ability to produce antibacterial and anticancer metabolites. The isolates were found to be functionally versatile as they produced extracellular bioactive molecules that exhibited high frequency of activities against <jats:italic>Bacillus cereus<\/jats:italic>, <jats:italic>Mycobacterium smegmatis<\/jats:italic>, <jats:italic>Enterobacter cloacae<\/jats:italic> and <jats:italic>Pseudomonas syringae<\/jats:italic>. The strains also showed cytotoxic activity against the human cancer cell lines of liver, pancreas, prostrate, bone and cervix. These results indicate the importance of isolating diverse strains of myxobacteria from unexplored habitats to find novel bioactive compounds. Moreover, the bioactive molecules explored in this study are predominantly hydrophilic compounds, obviating the limitations of solubility-related aspect of drug discovery.<\/jats:p>","DOI":"10.1007\/s13205-017-0722-9","type":"journal-article","created":{"date-parts":[[2017,5,31]],"date-time":"2017-05-31T05:02:42Z","timestamp":1496206962000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Molecular and functional characterization of myxobacteria isolated from soil in India"],"prefix":"10.1007","volume":"7","author":[{"given":"Shiv","family":"Kumar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arun Kumar","family":"Yadav","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priyanka","family":"Chambel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramandeep","family":"Kaur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,5,31]]},"reference":[{"key":"722_CR1","doi-asserted-by":"publisher","first-page":"495","DOI":"10.1021\/np9804233","volume":"62","author":"JW Ahn","year":"1999","unstructured":"Ahn JW, Woo SH, Lee CO, Cho KY, Kim BS (1999) KR025, a new cytotoxic compound from Myxococcus fulvus. 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