{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T07:59:23Z","timestamp":1793260763984,"version":"4.5.0"},"reference-count":171,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T00:00:00Z","timestamp":1770595200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T00:00:00Z","timestamp":1770595200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"Central University of Punjab; Research Seed Money","award":["CUPB\/Director,(R&D)\/2023\/133"],"award-info":[{"award-number":["CUPB\/Director,(R&D)\/2023\/133"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["3 Biotech"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1007\/s13205-026-04712-3","type":"journal-article","created":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T06:20:11Z","timestamp":1770618011000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Microplastic exposure and human health: an integrative toxicological perspective"],"prefix":"10.1007","volume":"16","author":[{"given":"Akanksha","family":"Singh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Lalbiaktluangi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jawahar","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamla","family":"Kant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amit","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Balachandar","family":"Vellingiri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahalaxami","family":"Iyar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jagadeesh Nagarajappa","family":"Masagalli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heera","family":"Ram","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4703-8554","authenticated-orcid":false,"given":"Mukesh Kumar","family":"Yadav","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,2,9]]},"reference":[{"key":"4712_CR1","doi-asserted-by":"publisher","first-page":"125688","DOI":"10.1016\/j.polymer.2023.125688","volume":"267","author":"C Abreu","year":"2023","unstructured":"Abreu C, Rezende T, Serra A, Fonseca A, Braslau R, Coelho J (2023) Convenient and industrially viable internal plasticization of Poly(Vinyl chloride): copolymerization of vinyl chloride and commercial monomers. Polymer 267:125688. https:\/\/doi.org\/10.1016\/j.polymer.2023.125688","journal-title":"Polymer"},{"key":"4712_CR2","doi-asserted-by":"publisher","first-page":"1178434","DOI":"10.3389\/fimmu.2023.1178434","volume":"14","author":"A Alijagic","year":"2023","unstructured":"Alijagic A, Hedbrant A, Persson A, Larsson M, Engwall M, S\u00e4rndahl E (2023) NLRP3 inflammasome as a sensor of micro- and nanoplastics immunotoxicity. Front Immunol 14:1178434. https:\/\/doi.org\/10.3389\/fimmu.2023.1178434","journal-title":"Front Immunol"},{"key":"4712_CR3","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1016\/j.etap.2019.03.001","volume":"68","author":"CG Alimba","year":"2019","unstructured":"Alimba CG, Faggio C (2019) Microplastics in the marine environment: current trends in environmental pollution and mechanisms of toxicological profile. Environ Toxicol Pharmacol 68:61\u201374. https:\/\/doi.org\/10.1016\/j.etap.2019.03.001","journal-title":"Environ Toxicol Pharmacol"},{"key":"4712_CR4","doi-asserted-by":"publisher","first-page":"126124","DOI":"10.1016\/j.jhazmat.2021.126124","volume":"416","author":"LF Amato-Louren\u00e7o","year":"2021","unstructured":"Amato-Louren\u00e7o LF, Carvalho-Oliveira R, J\u00fanior GR, Dos Santos Galv\u00e3o L, Ando RA, Mauad T (2021) Presence of airborne microplastics in human lung tissue. J Hazard Mater 416:126124. https:\/\/doi.org\/10.1016\/j.jhazmat.2021.126124","journal-title":"J Hazard Mater"},{"key":"4712_CR5","doi-asserted-by":"publisher","unstructured":"Ammar E, Mohamed MS, Sayed AE-DH (2022) Polyethylene microplastics increases the tissue damage caused by 4-nonylphenol in the common carp (Cyprinus carpio) juvenile [Original Research]. Frontiers in Marine Science, Volume 9\u20132022. https:\/\/doi.org\/10.3389\/fmars.2022.1041003","DOI":"10.3389\/fmars.2022.1041003"},{"key":"4712_CR6","doi-asserted-by":"publisher","first-page":"152665","DOI":"10.1016\/j.tox.2020.152665","volume":"449","author":"R An","year":"2021","unstructured":"An R, Wang X, Yang L, Zhang J, Wang N, Xu F, Hou Y, Zhang H, Zhang L (2021) Polystyrene microplastics cause granulosa cells apoptosis and fibrosis in ovary through oxidative stress in rats. Toxicology 449:152665. https:\/\/doi.org\/10.1016\/j.tox.2020.152665","journal-title":"Toxicology"},{"issue":"8","key":"4712_CR8","doi-asserted-by":"publisher","first-page":"1596","DOI":"10.1016\/j.marpolbul.2011.05.030","volume":"62","author":"AL Andrady","year":"2011","unstructured":"Andrady AL (2011) Microplastics in the marine environment. Mar Pollut Bull 62(8):1596\u20131605. https:\/\/doi.org\/10.1016\/j.marpolbul.2011.05.030","journal-title":"Mar Pollut Bull"},{"issue":"2","key":"4712_CR9","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1016\/s0889-8529(05)70139-0","volume":"29","author":"AR Ayala","year":"2000","unstructured":"Ayala AR, Danese MD, Ladenson PW (2000) When to treat mild hypothyroidism. Endocrinol Metab Clin North Am 29(2):399\u2013415. https:\/\/doi.org\/10.1016\/s0889-8529(05)70139-0","journal-title":"Endocrinol Metab Clin North Am"},{"key":"4712_CR10","doi-asserted-by":"publisher","first-page":"150263","DOI":"10.1016\/j.scitotenv.2021.150263","volume":"806","author":"C-L Bai","year":"2022","unstructured":"Bai C-L, Liu L-Y, Hu Y-B, Zeng EY, Guo Y (2022) Microplastics: A review of analytical methods, occurrence and characteristics in food, and potential toxicities to biota. Sci Total Environ 806:150263. https:\/\/doi.org\/10.1016\/j.scitotenv.2021.150263","journal-title":"Sci Total Environ"},{"key":"4712_CR11","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1016\/j.marpolbul.2018.05.047","volume":"133","author":"LGA Barboza","year":"2018","unstructured":"Barboza LGA, Dick Vethaak A, Lavorante BRBO, Lundebye A-K, Guilhermino L (2018) Marine microplastic debris: an emerging issue for food security, food safety and human health. Mar Pollut Bull 133:336\u2013348. https:\/\/doi.org\/10.1016\/j.marpolbul.2018.05.047","journal-title":"Mar Pollut Bull"},{"issue":"1","key":"4712_CR12","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1007\/s12013-015-0705-6","volume":"74","author":"G Barshtein","year":"2016","unstructured":"Barshtein G, Livshits L, Shvartsman LD, Shlomai NO, Yedgar S, Arbell D (2016) Polystyrene nanoparticles activate erythrocyte aggregation and adhesion to endothelial cells. Cell Biochem Biophys 74(1):19\u201327. https:\/\/doi.org\/10.1007\/s12013-015-0705-6","journal-title":"Cell Biochem Biophys"},{"key":"4712_CR13","doi-asserted-by":"publisher","first-page":"122102","DOI":"10.1016\/j.envpol.2023.122102","volume":"334","author":"V Beghetto","year":"2023","unstructured":"Beghetto V, Gatto V, Samiolo R, Scolaro C, Brahimi S, Facchin M, Visco A (2023) Plastics today: key challenges and EU strategies towards carbon neutrality: A review. Environ Pollut 334:122102. https:\/\/doi.org\/10.1016\/j.envpol.2023.122102","journal-title":"Environ Pollut"},{"issue":"2","key":"4712_CR14","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1111\/j.2042-7158.1996.tb07112.x","volume":"48","author":"DJ Begley","year":"1996","unstructured":"Begley DJ (1996) The blood-brain barrier: principles for targeting peptides and drugs to the central nervous system. J Pharm Pharmacol 48(2):136\u2013146. https:\/\/doi.org\/10.1111\/j.2042-7158.1996.tb07112.x","journal-title":"J Pharm Pharmacol"},{"issue":"13","key":"4712_CR15","doi-asserted-by":"publisher","first-page":"1618","DOI":"10.1096\/fj.04-1945fje","volume":"18","author":"ML Block","year":"2004","unstructured":"Block ML, Wu X, Pei Z, Li G, Wang T, Qin L, Wilson B, Yang J, Hong JS, Veronesi B (2004) Nanometer size diesel exhaust particles are selectively toxic to dopaminergic neurons: the role of microglia, phagocytosis, and NADPH oxidase. Faseb J 18(13):1618\u20131620. https:\/\/doi.org\/10.1096\/fj.04-1945fje","journal-title":"Faseb J"},{"issue":"10","key":"4712_CR16","doi-asserted-by":"publisher","first-page":"1458","DOI":"10.1289\/ehp.0901331","volume":"118","author":"M Boas","year":"2010","unstructured":"Boas M, Frederiksen H, Feldt-Rasmussen U, Skakkeb\u00e6k NE, Heged\u00fcs L, Hilsted L, Juul A, Main KM (2010) Childhood exposure to phthalates: associations with thyroid function, insulin-like growth factor I, and growth. Environ Health Perspect 118(10):1458\u20131464. https:\/\/doi.org\/10.1289\/ehp.0901331","journal-title":"Environ Health Perspect"},{"issue":"3","key":"4712_CR17","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1034\/j.1600-0625.2000.009003165.x","volume":"9","author":"JD Bos","year":"2000","unstructured":"Bos JD, Meinardi MM (2000) The 500 Dalton rule for the skin penetration of chemical compounds and drugs. Exp Dermatol 9(3):165\u2013169. https:\/\/doi.org\/10.1034\/j.1600-0625.2000.009003165.x","journal-title":"Exp Dermatol"},{"key":"4712_CR18","doi-asserted-by":"publisher","first-page":"116523","DOI":"10.1016\/j.envres.2023.116523","volume":"234","author":"N Bostan","year":"2023","unstructured":"Bostan N, Ilyas N, Akhtar N, Mehmood S, Saman RU, Sayyed RZ, Shatid AA, Alfaifi MY, Elbehairi SEI, Pandiaraj S (2023) Toxicity assessment of microplastic (MPs); a threat to the ecosystem. Environ Res 234:116523. https:\/\/doi.org\/10.1016\/j.envres.2023.116523","journal-title":"Environ Res"},{"key":"4712_CR19","doi-asserted-by":"publisher","unstructured":"Brahney J, Mahowald N, Prank M, Cornwell G, Klimont Z, Matsui H, Prather KA (2021) Constraining the atmospheric limb of the plastic cycle. Proc Natl Acad Sci U S A 118(16). https:\/\/doi.org\/10.1073\/pnas.2020719118","DOI":"10.1073\/pnas.2020719118"},{"key":"4712_CR20","doi-asserted-by":"publisher","unstructured":"Busch M, Bredeck G, Waag F, Rahimi K, Ramachandran H, Bessel T, Barcikowski S, Herrmann A, Rossi A, Schins RPF (2022) Assessing the NLRP3 inflammasome activating potential of a large panel of Micro- and nanoplastics in THP-1 cells. Biomolecules 12(8). https:\/\/doi.org\/10.3390\/biom12081095","DOI":"10.3390\/biom12081095"},{"issue":"4","key":"4712_CR22","doi-asserted-by":"publisher","first-page":"243","DOI":"10.4415\/ann_24_04_01","volume":"60","author":"T Catone","year":"2024","unstructured":"Catone T, Alivernini S, Attias L, Orr\u00f9 MA (2024) The European legislation on the restriction on intentionally added microplastics. Commentary. Ann Ist Super Sanita 60(4):243\u2013246. https:\/\/doi.org\/10.4415\/ann_24_04_01","journal-title":"Ann Ist Super Sanita"},{"issue":"3","key":"4712_CR23","doi-asserted-by":"publisher","first-page":"J234","DOI":"10.1016\/j.jaut.2009.11.009","volume":"34","author":"C Chang","year":"2010","unstructured":"Chang C (2010) The immune effects of naturally occurring and synthetic nanoparticles. J Autoimmun 34(3):J234\u2013246. https:\/\/doi.org\/10.1016\/j.jaut.2009.11.009","journal-title":"J Autoimmun"},{"key":"4712_CR24","doi-asserted-by":"publisher","first-page":"104938","DOI":"10.1016\/j.envint.2019.104938","volume":"130","author":"Q Chen","year":"2019","unstructured":"Chen Q, Allgeier A, Yin D, Hollert H (2019) Leaching of endocrine disrupting chemicals from marine microplastics and mesoplastics under common life stress conditions. Environ Int 130:104938. https:\/\/doi.org\/10.1016\/j.envint.2019.104938","journal-title":"Environ Int"},{"key":"4712_CR25","doi-asserted-by":"publisher","first-page":"128677","DOI":"10.1016\/j.chemosphere.2020.128677","volume":"269","author":"H Cheng","year":"2021","unstructured":"Cheng H, Feng Y, Duan Z, Duan X, Zhao S, Wang Y, Gong Z, Wang L (2021) Toxicities of microplastic fibers and granules on the development of zebrafish embryos and their combined effects with cadmium. Chemosphere 269:128677. https:\/\/doi.org\/10.1016\/j.chemosphere.2020.128677","journal-title":"Chemosphere"},{"key":"4712_CR26","doi-asserted-by":"publisher","unstructured":"Cheung LTO, Lui CY, Fok L (2018) Microplastic contamination of wild and captive Flathead grey mullet (Mugil cephalus). Int J Environ Res Public Health 15(4). https:\/\/doi.org\/10.3390\/ijerph15040597","DOI":"10.3390\/ijerph15040597"},{"issue":"12","key":"4712_CR27","doi-asserted-by":"publisher","first-page":"2588","DOI":"10.1016\/j.marpolbul.2011.09.025","volume":"62","author":"M Cole","year":"2011","unstructured":"Cole M, Lindeque P, Halsband C, Galloway TS (2011) Microplastics as contaminants in the marine environment: a review. Mar Pollut Bull 62(12):2588\u20132597. https:\/\/doi.org\/10.1016\/j.marpolbul.2011.09.025","journal-title":"Mar Pollut Bull"},{"issue":"9","key":"4712_CR28","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1016\/j.it.2016.06.006","volume":"37","author":"E Colombo","year":"2016","unstructured":"Colombo E, Farina C (2016) Astrocytes: key regulators of neuroinflammation. Trends Immunol 37(9):608\u2013620. https:\/\/doi.org\/10.1016\/j.it.2016.06.006","journal-title":"Trends Immunol"},{"key":"4712_CR30","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1016\/j.scitotenv.2019.03.368","volume":"671","author":"F Corradini","year":"2019","unstructured":"Corradini F, Meza P, Eguiluz R, Casado F, Huerta-Lwanga E, Geissen V (2019) Evidence of microplastic accumulation in agricultural soils from sewage sludge disposal. Sci Total Environ 671:411\u2013420. https:\/\/doi.org\/10.1016\/j.scitotenv.2019.03.368","journal-title":"Sci Total Environ"},{"issue":"5418","key":"4712_CR31","doi-asserted-by":"publisher","first-page":"1318","DOI":"10.1126\/science.284.5418.1318","volume":"284","author":"JW Costerton","year":"1999","unstructured":"Costerton JW, Stewart PS, Greenberg EP (1999) Bacterial biofilms: a common cause of persistent infections. Science 284(5418):1318\u20131322. https:\/\/doi.org\/10.1126\/science.284.5418.1318","journal-title":"Science"},{"issue":"12","key":"4712_CR32","doi-asserted-by":"publisher","first-page":"7068","DOI":"10.1021\/acs.est.9b01517","volume":"53","author":"KD Cox","year":"2019","unstructured":"Cox KD, Covernton GA, Davies HL, Dower JF, Juanes F, Dudas SE (2019) Human consumption of microplastics. Environ Sci Technol 53(12):7068\u20137074. https:\/\/doi.org\/10.1021\/acs.est.9b01517","journal-title":"Environ Sci Technol"},{"key":"4712_CR33","doi-asserted-by":"publisher","unstructured":"Crawford C, Quinn B (2017) The interactions of microplastics and chemical pollutants. In (pp. 131\u2013157). https:\/\/doi.org\/10.1016\/B978-0-12-809406-8.00006-2","DOI":"10.1016\/B978-0-12-809406-8.00006-2"},{"key":"4712_CR34","doi-asserted-by":"publisher","unstructured":"D\u2019Angelo S, Meccariello R (2021) Microplastics: A threat for male fertility. Int J Environ Res Public Health 18(5). https:\/\/doi.org\/10.3390\/ijerph18052392","DOI":"10.3390\/ijerph18052392"},{"issue":"7","key":"4712_CR35","doi-asserted-by":"publisher","first-page":"e0236838","DOI":"10.1371\/journal.pone.0236838","volume":"15","author":"E Danopoulos","year":"2020","unstructured":"Danopoulos E, Twiddy M, Rotchell JM (2020) Microplastic contamination of drinking water: A systematic review. PLoS ONE 15(7):e0236838. https:\/\/doi.org\/10.1371\/journal.pone.0236838","journal-title":"PLoS ONE"},{"issue":"10","key":"4712_CR36","doi-asserted-by":"publisher","first-page":"6044","DOI":"10.1021\/acs.est.9b01339","volume":"53","author":"AA de Souza Machado","year":"2019","unstructured":"de Souza Machado AA, Lau CW, Kloas W, Bergmann J, Bachelier JB, Faltin E, Becker R, G\u00f6rlich AS, Rillig MC (2019) Microplastics can change soil properties and affect plant performance. Environ Sci Technol 53(10):6044\u20136052. https:\/\/doi.org\/10.1021\/acs.est.9b01339","journal-title":"Environ Sci Technol"},{"issue":"1","key":"4712_CR37","doi-asserted-by":"publisher","first-page":"46687","DOI":"10.1038\/srep46687","volume":"7","author":"Y Deng","year":"2017","unstructured":"Deng Y, Zhang Y, Lemos B, Ren H (2017) Tissue accumulation of microplastics in mice and biomarker responses suggest widespread health risks of exposure. Sci Rep 7(1):46687. https:\/\/doi.org\/10.1038\/srep46687","journal-title":"Sci Rep"},{"key":"4712_CR38","doi-asserted-by":"publisher","first-page":"106795","DOI":"10.1016\/j.envint.2021.106795","volume":"157","author":"A Derakhshan","year":"2021","unstructured":"Derakhshan A, Shu H, Broeren MAC, Lindh CH, Peeters RP, Kortenkamp A, Demeneix B, Bornehag CG, Korevaar TIM (2021) Association of phthalate exposure with thyroid function during pregnancy. Environ Int 157:106795. https:\/\/doi.org\/10.1016\/j.envint.2021.106795","journal-title":"Environ Int"},{"issue":"7","key":"4712_CR39","doi-asserted-by":"publisher","first-page":"247","DOI":"10.3109\/09687688.2010.522203","volume":"27","author":"P Desai","year":"2010","unstructured":"Desai P, Patlolla RR, Singh M (2010) Interaction of nanoparticles and cell-penetrating peptides with skin for transdermal drug delivery. Mol Membr Biol 27(7):247\u2013259. https:\/\/doi.org\/10.3109\/09687688.2010.522203","journal-title":"Mol Membr Biol"},{"key":"4712_CR40","doi-asserted-by":"publisher","first-page":"125969","DOI":"10.1016\/j.jhazmat.2021.125969","volume":"416","author":"A Dimitriadi","year":"2021","unstructured":"Dimitriadi A, Papaefthimiou C, Genizegkini E, Sampsonidis I, Kalogiannis S, Feidantsis K, Bobori DC, Kastrinaki G, Koumoundouros G, Lambropoulou DA, Kyzas GZ, Bikiaris DN (2021) Adverse effects polystyrene microplastics exert on zebrafish heart - Molecular to individual level. J Hazard Mater 416:125969. https:\/\/doi.org\/10.1016\/j.jhazmat.2021.125969","journal-title":"J Hazard Mater"},{"key":"4712_CR41","doi-asserted-by":"publisher","first-page":"119269","DOI":"10.1016\/j.envpol.2022.119269","volume":"305","author":"T Ding","year":"2022","unstructured":"Ding T, Yan W, Zhou T, Shen W, Wang T, Li M, Zhou S, Wu M, Dai J, Huang K, Zhang J, Chang J, Wang S (2022) Endocrine disrupting chemicals impact on ovarian aging: evidence from epidemiological and experimental evidence. Environ Pollut 305:119269. https:\/\/doi.org\/10.1016\/j.envpol.2022.119269","journal-title":"Environ Pollut"},{"key":"4712_CR42","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1016\/j.envpol.2016.12.013","volume":"221","author":"R Dris","year":"2017","unstructured":"Dris R, Gasperi J, Mirande C, Mandin C, Guerrouache M, Langlois V, Tassin B (2017) A first overview of textile fibers, including microplastics, in indoor and outdoor environments. Environ Pollut 221:453\u2013458. https:\/\/doi.org\/10.1016\/j.envpol.2016.12.013","journal-title":"Environ Pollut"},{"key":"4712_CR43","doi-asserted-by":"publisher","first-page":"134065","DOI":"10.1016\/j.matlet.2023.134065","volume":"338","author":"A Emanuel Ximim Gavim","year":"2023","unstructured":"Emanuel Ximim Gavim A, Mascarenhas R, Sbrissia L, J\u00fanior J, Casagrande T, Macedo A (2023) Identifying the manufacturing process of PVC films by nondestructive morphological analyses. Mater Lett 338:134065. https:\/\/doi.org\/10.1016\/j.matlet.2023.134065","journal-title":"Mater Lett"},{"key":"4712_CR44","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1016\/j.marpolbul.2019.04.030","volume":"143","author":"G Fackelmann","year":"2019","unstructured":"Fackelmann G, Sommer S (2019) Microplastics and the gut microbiome: how chronically exposed species May suffer from gut dysbiosis. Mar Pollut Bull 143:193\u2013203. https:\/\/doi.org\/10.1016\/j.marpolbul.2019.04.030","journal-title":"Mar Pollut Bull"},{"key":"4712_CR45","doi-asserted-by":"publisher","first-page":"107223","DOI":"10.1016\/j.envint.2022.107223","volume":"163","author":"Z Fan","year":"2022","unstructured":"Fan Z, Xiao T, Luo H, Chen D, Lu K, Shi W, Sun C, Bian Q (2022) A study on the roles of long non-coding RNA and circular RNA in the pulmonary injuries induced by polystyrene microplastics. Environ Int 163:107223. https:\/\/doi.org\/10.1016\/j.envint.2022.107223","journal-title":"Environ Int"},{"issue":"8","key":"4712_CR46","doi-asserted-by":"publisher","first-page":"1225","DOI":"10.1016\/j.marpolbul.2009.04.025","volume":"58","author":"LS Fendall","year":"2009","unstructured":"Fendall LS, Sewell MA (2009) Contributing to marine pollution by washing your face: microplastics in facial cleansers. Mar Pollut Bull 58(8):1225\u20131228. https:\/\/doi.org\/10.1016\/j.marpolbul.2009.04.025","journal-title":"Mar Pollut Bull"},{"issue":"4","key":"4712_CR47","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1016\/j.eehl.2023.08.002","volume":"2","author":"Y Feng","year":"2023","unstructured":"Feng Y, Tu C, Li R, Wu D, Yang J, Xia Y, Peijnenburg W, Luo Y (2023) A systematic review of the impacts of exposure to micro- and nano-plastics on human tissue accumulation and health. Eco Environ Health 2(4):195\u2013207. https:\/\/doi.org\/10.1016\/j.eehl.2023.08.002","journal-title":"Eco Environ Health"},{"key":"4712_CR48","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1016\/j.tiv.2015.11.006","volume":"31","author":"M Forte","year":"2016","unstructured":"Forte M, Iachetta G, Tussellino M, Carotenuto R, Prisco M, De Falco M, Laforgia V, Valiante S (2016) Polystyrene nanoparticles internalization in human gastric adenocarcinoma cells. Toxicol Vitro 31:126\u2013136. https:\/\/doi.org\/10.1016\/j.tiv.2015.11.006","journal-title":"Toxicol Vitro"},{"issue":"1","key":"4712_CR49","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1186\/s12302-018-0139-z","volume":"30","author":"F Gallo","year":"2018","unstructured":"Gallo F, Fossi C, Weber R, Santillo D, Sousa J, Ingram I, Nadal A, Romano D (2018) Marine litter plastics and microplastics and their toxic chemicals components: the need for urgent preventive measures. Environ Sci Eur 30(1):13. https:\/\/doi.org\/10.1186\/s12302-018-0139-z","journal-title":"Environ Sci Eur"},{"key":"4712_CR50","doi-asserted-by":"publisher","unstructured":"Gaspar L, Bartman S, Coppotelli G, Ross JM (2023) Acute exposure to microplastics induced changes in behavior and inflammation in young and old mice. Int J Mol Sci 24(15). https:\/\/doi.org\/10.3390\/ijms241512308","DOI":"10.3390\/ijms241512308"},{"issue":"7","key":"4712_CR52","doi-asserted-by":"publisher","first-page":"e1700782","DOI":"10.1126\/sciadv.1700782","volume":"3","author":"R Geyer","year":"2017","unstructured":"Geyer R, Jambeck JR, Law KL (2017) Production, use, and fate of all plastics ever made. Sci Adv 3(7):e1700782. https:\/\/doi.org\/10.1126\/sciadv.1700782","journal-title":"Sci Adv"},{"issue":"1","key":"4712_CR53","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1186\/s12978-020-01048-w","volume":"17","author":"M Ghorbani","year":"2020","unstructured":"Ghorbani M, Hosseini FS, Yunesian M, Keramat A (2020) Dropout of infertility treatments and related factors among infertile couples. Reprod Health 17(1):192. https:\/\/doi.org\/10.1186\/s12978-020-01048-w","journal-title":"Reprod Health"},{"key":"4712_CR54","doi-asserted-by":"publisher","first-page":"149921","DOI":"10.1016\/j.scitotenv.2021.149921","volume":"803","author":"M Hamed","year":"2022","unstructured":"Hamed M, Monteiro CE, Sayed AEH (2022) Investigation of the impact caused by different sizes of polyethylene plastics (nano, micro, and macro) in common carp juveniles, Cyprinus Carpio L., using multi-biomarkers. Sci Total Environ 803:149921. https:\/\/doi.org\/10.1016\/j.scitotenv.2021.149921","journal-title":"Sci Total Environ"},{"key":"4712_CR55","doi-asserted-by":"publisher","first-page":"126074","DOI":"10.1016\/j.jhazmat.2021.126074","volume":"417","author":"YJ He","year":"2021","unstructured":"He YJ, Qin Y, Zhang TL, Zhu YY, Wang ZJ, Zhou ZS, Xie TZ, Luo XD (2021) Migration of (non-) intentionally added substances and microplastics from microwavable plastic food containers. J Hazard Mater 417:126074. https:\/\/doi.org\/10.1016\/j.jhazmat.2021.126074","journal-title":"J Hazard Mater"},{"key":"4712_CR56","doi-asserted-by":"publisher","first-page":"248","DOI":"10.3389\/fcimb.2020.00248","volume":"10","author":"M Herath","year":"2020","unstructured":"Herath M, Hosie S, Bornstein JC, Franks AE, Hill-Yardin EL (2020) The role of the Gastrointestinal mucus system in intestinal homeostasis: implications for neurological disorders. Front Cell Infect Microbiol 10:248. https:\/\/doi.org\/10.3389\/fcimb.2020.00248","journal-title":"Front Cell Infect Microbiol"},{"key":"4712_CR57","doi-asserted-by":"publisher","unstructured":"Hermans E, Bhamla S, Kao P, Fuller G, Vermant J (2015) Lung surfactants and different contributions to thin film stability. Soft Matter 11. https:\/\/doi.org\/10.1039\/c5sm01603g","DOI":"10.1039\/c5sm01603g"},{"issue":"7","key":"4712_CR59","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1021\/acs.estlett.7b00187","volume":"4","author":"LM Hernandez","year":"2017","unstructured":"Hernandez LM, Yousefi N, Tufenkji N (2017) Are there nanoplastics in your personal care products? Environ Sci Technol Lett 4(7):280\u2013285. https:\/\/doi.org\/10.1021\/acs.estlett.7b00187","journal-title":"Environ Sci Technol Lett"},{"issue":"21","key":"4712_CR58","doi-asserted-by":"publisher","first-page":"12300","DOI":"10.1021\/acs.est.9b02540","volume":"53","author":"LM Hernandez","year":"2019","unstructured":"Hernandez LM, Xu EG, Larsson HCE, Tahara R, Maisuria VB, Tufenkji N (2019) Plastic teabags release billions of microparticles and nanoparticles into tea. Environ Sci Technol 53(21):12300\u201312310. https:\/\/doi.org\/10.1021\/acs.est.9b02540","journal-title":"Environ Sci Technol"},{"issue":"1","key":"4712_CR60","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1186\/s12989-020-00387-7","volume":"17","author":"N Hirt","year":"2020","unstructured":"Hirt N, Body-Malapel M (2020) Immunotoxicity and intestinal effects of nano- and microplastics: a review of the literature. Part Fibre Toxicol 17(1):57. https:\/\/doi.org\/10.1186\/s12989-020-00387-7","journal-title":"Part Fibre Toxicol"},{"key":"4712_CR61","doi-asserted-by":"publisher","first-page":"166258","DOI":"10.1016\/j.scitotenv.2023.166258","volume":"903","author":"Y Hong","year":"2023","unstructured":"Hong Y, Wu S, Wei G (2023) Adverse effects of microplastics and nanoplastics on the reproductive system: A comprehensive review of fertility and potential harmful interactions. Sci Total Environ 903:166258. https:\/\/doi.org\/10.1016\/j.scitotenv.2023.166258","journal-title":"Sci Total Environ"},{"key":"4712_CR62","doi-asserted-by":"publisher","first-page":"124028","DOI":"10.1016\/j.jhazmat.2020.124028","volume":"405","author":"B Hou","year":"2021","unstructured":"Hou B, Wang F, Liu T, Wang Z (2021a) Reproductive toxicity of polystyrene microplastics: in vivo experimental study on testicular toxicity in mice. J Hazard Mater 405:124028. https:\/\/doi.org\/10.1016\/j.jhazmat.2020.124028","journal-title":"J Hazard Mater"},{"key":"4712_CR63","doi-asserted-by":"publisher","first-page":"112012","DOI":"10.1016\/j.ecoenv.2021.112012","volume":"212","author":"J Hou","year":"2021","unstructured":"Hou J, Lei Z, Cui L, Hou Y, Yang L, An R, Wang Q, Li S, Zhang H, Zhang L (2021b) Polystyrene microplastics lead to pyroptosis and apoptosis of ovarian granulosa cells via NLRP3\/Caspase-1 signaling pathway in rats. Ecotoxicol Environ Saf 212:112012. https:\/\/doi.org\/10.1016\/j.ecoenv.2021.112012","journal-title":"Ecotoxicol Environ Saf"},{"key":"4712_CR64","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1016\/j.reprotox.2021.10.002","volume":"106","author":"J Hu","year":"2021","unstructured":"Hu J, Qin X, Zhang J, Zhu Y, Zeng W, Lin Y, Liu X (2021) Polystyrene microplastics disturb maternal-fetal immune balance and cause reproductive toxicity in pregnant mice. Reprod Toxicol 106:42\u201350. https:\/\/doi.org\/10.1016\/j.reprotox.2021.10.002","journal-title":"Reprod Toxicol"},{"key":"4712_CR66","doi-asserted-by":"publisher","first-page":"107187","DOI":"10.1016\/j.foodcont.2020.107187","volume":"113","author":"Y Huang","year":"2020","unstructured":"Huang Y, Chapman J, Yong feng D, Cozzolino D (2020) Rapid measurement of microplastic contamination in chicken meat by mid infrared spectroscopy and chemometrics: A feasibility study. Food Control 113:107187. https:\/\/doi.org\/10.1016\/j.foodcont.2020.107187","journal-title":"Food Control"},{"issue":"4","key":"4712_CR65","doi-asserted-by":"publisher","first-page":"2476","DOI":"10.1021\/acs.est.1c03859","volume":"56","author":"S Huang","year":"2022","unstructured":"Huang S, Huang X, Bi R, Guo Q, Yu X, Zeng Q, Huang Z, Liu T, Wu H, Chen Y, Xu J, Wu Y, Guo P (2022) Detection and analysis of microplastics in human sputum. Environ Sci Technol 56(4):2476\u20132486. https:\/\/doi.org\/10.1021\/acs.est.1c03859","journal-title":"Environ Sci Technol"},{"issue":"1","key":"4712_CR67","doi-asserted-by":"publisher","first-page":"7391","DOI":"10.1038\/s41598-020-64464-9","volume":"10","author":"J Hwang","year":"2020","unstructured":"Hwang J, Choi D, Han S, Jung SY, Choi J, Hong J (2020) Potential toxicity of polystyrene microplastic particles. Sci Rep 10(1):7391. https:\/\/doi.org\/10.1038\/s41598-020-64464-9","journal-title":"Sci Rep"},{"key":"4712_CR68","doi-asserted-by":"publisher","unstructured":"Islam S, Rahman M, Larpruenrudee P, Arsalanloo A, Beni M, Islam HR, Gu M, Y., Sauret E (2023) How microplastics are transported and deposited in realistic upper airways? Phys Fluids 35. https:\/\/doi.org\/10.1063\/5.0150703","DOI":"10.1063\/5.0150703"},{"issue":"7","key":"4712_CR69","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1007\/s10653-024-02033-z","volume":"46","author":"J Jiang","year":"2024","unstructured":"Jiang J, Shu Z, Qiu L (2024) Adverse effects and potential mechanisms of polystyrene microplastics (PS-MPs) on the blood-testis barrier. Environ Geochem Health 46(7):238. https:\/\/doi.org\/10.1007\/s10653-024-02033-z","journal-title":"Environ Geochem Health"},{"issue":"1","key":"4712_CR70","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1186\/s12989-022-00453-2","volume":"19","author":"H Jin","year":"2022","unstructured":"Jin H, Yan M, Pan C, Liu Z, Sha X, Jiang C, Li L, Pan M, Li D, Han X, Ding J (2022) Chronic exposure to polystyrene microplastics induced male reproductive toxicity and decreased testosterone levels via the LH-mediated LHR\/cAMP\/PKA\/StAR pathway. Part Fibre Toxicol 19(1):13. https:\/\/doi.org\/10.1186\/s12989-022-00453-2","journal-title":"Part Fibre Toxicol"},{"key":"4712_CR71","doi-asserted-by":"publisher","first-page":"120442","DOI":"10.1016\/j.envpol.2022.120442","volume":"315","author":"YS Jung","year":"2022","unstructured":"Jung YS, Sampath V, Prunicki M, Aguilera J, Allen H, LaBeaud D, Veidis E, Barry M, Erny B, Patel L, Akdis C, Akdis M, Nadeau K (2022) Characterization and regulation of microplastic pollution for protecting planetary and human health. Environ Pollut 315:120442. https:\/\/doi.org\/10.1016\/j.envpol.2022.120442","journal-title":"Environ Pollut"},{"issue":"1","key":"4712_CR72","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1016\/j.jfda.2014.01.012","volume":"22","author":"A Karmakar","year":"2014","unstructured":"Karmakar A, Zhang Q, Zhang Y (2014) Neurotoxicity of nanoscale materials. J Food Drug Anal 22(1):147\u2013160. https:\/\/doi.org\/10.1016\/j.jfda.2014.01.012","journal-title":"J Food Drug Anal"},{"key":"4712_CR73","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1016\/j.marpolbul.2019.06.066","volume":"146","author":"M Kazour","year":"2019","unstructured":"Kazour M, Terki S, Rabhi K, Jemaa S, Khalaf G, Amara R (2019) Sources of microplastics pollution in the marine environment: importance of wastewater treatment plant and coastal landfill. Mar Pollut Bull 146:608\u2013618. https:\/\/doi.org\/10.1016\/j.marpolbul.2019.06.066","journal-title":"Mar Pollut Bull"},{"issue":"21","key":"4712_CR74","doi-asserted-by":"publisher","first-page":"12819","DOI":"10.1021\/acs.est.8b04180","volume":"52","author":"JS Kim","year":"2018","unstructured":"Kim JS, Lee HJ, Kim SK, Kim HJ (2018) Global pattern of microplastics (MPs) in commercial Food-Grade salts: sea salt as an indicator of seawater MP pollution. Environ Sci Technol 52(21):12819\u201312828. https:\/\/doi.org\/10.1021\/acs.est.8b04180","journal-title":"Environ Sci Technol"},{"key":"4712_CR75","doi-asserted-by":"publisher","first-page":"129715","DOI":"10.1016\/j.jhazmat.2022.129715","volume":"440","author":"L Kim","year":"2022","unstructured":"Kim L, Cui R, Kwak I, J., An YJ (2022) Trophic transfer of nanoplastics through a microalgae-crustacean-small yellow croaker food chain: Inhibition of digestive enzyme activity in fish. J Hazard Mater 440:129715. https:\/\/doi.org\/10.1016\/j.jhazmat.2022.129715","journal-title":"J Hazard Mater"},{"issue":"1","key":"4712_CR76","doi-asserted-by":"publisher","first-page":"181","DOI":"10.5530\/ajbls.2022.11.25","volume":"11","author":"R Kiruba","year":"2022","unstructured":"Kiruba R, Preethi M, Aganasteen R, Rithick Raj M, Hannah Thabitha C, Monica P, Sakthivel J, Levince C, Banu N, I (2022) Identification of microplastics as emerging contaminant in branded milk of Tamil Nadu State, India. Asian J Biol Life Sci 11(1):181","journal-title":"Asian J Biol Life Sci"},{"key":"4712_CR77","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1111\/j.1749-6632.2009.04453.x","volume":"1163","author":"W Kloas","year":"2009","unstructured":"Kloas W, Urbatzka R, Opitz R, W\u00fcrtz S, Behrends T, Hermelink B, Hofmann F, Jagnytsch O, Kroupova H, Lorenz C, Neumann N, Pietsch C, Trubiroha A, Van Ballegooy C, Wiedemann C, Lutz I (2009) Endocrine disruption in aquatic vertebrates. Ann N Y Acad Sci 1163:187\u2013200. https:\/\/doi.org\/10.1111\/j.1749-6632.2009.04453.x","journal-title":"Ann N Y Acad Sci"},{"issue":"1\u20132","key":"4712_CR78","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/j.ijpharm.2003.10.038","volume":"275","author":"AK Kohli","year":"2004","unstructured":"Kohli AK, Alpar HO (2004) Potential use of nanoparticles for transcutaneous vaccine delivery: effect of particle size and charge. Int J Pharm 275(1\u20132):13\u201317. https:\/\/doi.org\/10.1016\/j.ijpharm.2003.10.038","journal-title":"Int J Pharm"},{"issue":"4","key":"4712_CR79","doi-asserted-by":"publisher","first-page":"e0194970","DOI":"10.1371\/journal.pone.0194970","volume":"13","author":"M Kosuth","year":"2018","unstructured":"Kosuth M, Mason SA, Wattenberg EV (2018) Anthropogenic contamination of tap water, beer, and sea salt. PLoS ONE 13(4):e0194970. https:\/\/doi.org\/10.1371\/journal.pone.0194970","journal-title":"PLoS ONE"},{"key":"4712_CR80","doi-asserted-by":"publisher","unstructured":"Kumar R, Manna C, Padha S, Verma A, Sharma P, Dhar A, Ghosh A, Bhattacharya P (2022) Micro(nano)plastics pollution and human health: How plastics can induce carcinogenesis to humans? Chemosphere, 298, 134267. https:\/\/doi.org\/10.1016\/j.chemosphere.2022.134267","DOI":"10.1016\/j.chemosphere.2022.134267"},{"key":"4712_CR81","doi-asserted-by":"publisher","first-page":"136823","DOI":"10.1016\/j.scitotenv.2020.136823","volume":"714","author":"G Kutralam-Muniasamy","year":"2020","unstructured":"Kutralam-Muniasamy G, P\u00e9rez-Guevara F, Elizalde-Mart\u00ednez I, Shruti VC (2020) Branded milks - Are they immune from microplastics contamination? Sci Total Environ 714:136823. https:\/\/doi.org\/10.1016\/j.scitotenv.2020.136823","journal-title":"Sci Total Environ"},{"key":"4712_CR82","doi-asserted-by":"publisher","unstructured":"Kwon JH, Kim JW, Pham TD, Tarafdar A, Hong S, Chun SH, Lee SH, Kang DY, Kim JY, Kim SB, Jung J (2020) Microplastics in food: A review on analytical methods and challenges. Int J Environ Res Public Health 17(18). https:\/\/doi.org\/10.3390\/ijerph17186710","DOI":"10.3390\/ijerph17186710"},{"issue":"6193","key":"4712_CR84","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1126\/science.1254065","volume":"345","author":"KL Law","year":"2014","unstructured":"Law KL, Thompson RC (2014) Oceans. Microplastics in the seas. Science 345(6193):144\u2013145. https:\/\/doi.org\/10.1126\/science.1254065","journal-title":"Science"},{"issue":"3","key":"4712_CR85","doi-asserted-by":"publisher","first-page":"678","DOI":"10.1128\/aem.57.3.678-685.1991","volume":"57","author":"B Lee","year":"1991","unstructured":"Lee B, Pometto AL, Fratzke A, Bailey TB (1991) Biodegradation of degradable plastic polyethylene by phanerochaete and streptomyces species. Appl Environ Microbiol 57(3):678\u2013685. https:\/\/doi.org\/10.1128\/aem.57.3.678-685.1991","journal-title":"Appl Environ Microbiol"},{"issue":"4","key":"4712_CR86","doi-asserted-by":"publisher","first-page":"1748","DOI":"10.1021\/acs.est.8b05512","volume":"53","author":"R Lehner","year":"2019","unstructured":"Lehner R, Weder C, Petri-Fink A, Rothen-Rutishauser B (2019) Emergence of nanoplastic in the environment and possible impact on human health. Environ Sci Technol 53(4):1748\u20131765. https:\/\/doi.org\/10.1021\/acs.est.8b05512","journal-title":"Environ Sci Technol"},{"key":"4712_CR87","doi-asserted-by":"crossref","unstructured":"Lewandowski K, Sk\u00f3rczewska K (2022) A Brief Review of Poly(Vinyl Chloride) (PVC) Recycling. Polymers, 14(15), 3035. https:\/\/www.mdpi.com\/2073-4360\/14\/15\/3035","DOI":"10.3390\/polym14153035"},{"issue":"11","key":"4712_CR89","doi-asserted-by":"publisher","first-page":"2302","DOI":"10.1016\/j.biocel.2009.05.016","volume":"41","author":"MW Li","year":"2009","unstructured":"Li MW, Mruk DD, Lee WM, Cheng CY (2009) Disruption of the blood-testis barrier integrity by bisphenol A in vitro: is this a suitable model for studying blood-testis barrier dynamics? Int J Biochem Cell Biol 41(11):2302\u20132314. https:\/\/doi.org\/10.1016\/j.biocel.2009.05.016","journal-title":"Int J Biochem Cell Biol"},{"issue":"Pt A","key":"4712_CR92","doi-asserted-by":"publisher","first-page":"115025","DOI":"10.1016\/j.envpol.2020.115025","volume":"265","author":"Z Li","year":"2020","unstructured":"Li Z, Zhu S, Liu Q, Wei J, Jin Y, Wang X, Zhang L (2020) Polystyrene microplastics cause cardiac fibrosis by activating Wnt\/\u03b2-catenin signaling pathway and promoting cardiomyocyte apoptosis in rats. Environ Pollut 265(Pt A):115025. https:\/\/doi.org\/10.1016\/j.envpol.2020.115025","journal-title":"Environ Pollut"},{"key":"4712_CR91","doi-asserted-by":"publisher","first-page":"123933","DOI":"10.1016\/j.jhazmat.2020.123933","volume":"402","author":"S Li","year":"2021","unstructured":"Li S, Shi M, Wang Y, Xiao Y, Cai D, Xiao F (2021) Keap1-Nrf2 pathway up-regulation via hydrogen sulfide mitigates polystyrene microplastics induced-hepatotoxic effects. J Hazard Mater 402:123933. https:\/\/doi.org\/10.1016\/j.jhazmat.2020.123933","journal-title":"J Hazard Mater"},{"key":"4712_CR88","doi-asserted-by":"publisher","first-page":"127872","DOI":"10.1016\/j.jhazmat.2021.127872","volume":"427","author":"L Li","year":"2022","unstructured":"Li L, Xu Y, Li S, Zhang X, Feng H, Dai Y, Zhao J, Yue T (2022) Molecular modeling of nanoplastic transformations in alveolar fluid and impacts on the lung surfactant film. J Hazard Mater 427:127872. https:\/\/doi.org\/10.1016\/j.jhazmat.2021.127872","journal-title":"J Hazard Mater"},{"key":"4712_CR90","doi-asserted-by":"publisher","first-page":"129911","DOI":"10.1016\/j.jhazmat.2022.129911","volume":"441","author":"Q Li","year":"2023","unstructured":"Li Q, Yuan M, Chen Y, Jin X, Shangguan J, Cui J, Chang S, Guo M, Wang Y (2023) The neglected potential source of microplastics from daily necessities: A study on protective mobile phone cases. J Hazard Mater 441:129911. https:\/\/doi.org\/10.1016\/j.jhazmat.2022.129911","journal-title":"J Hazard Mater"},{"issue":"12","key":"4712_CR93","doi-asserted-by":"publisher","first-page":"2136","DOI":"10.1080\/19440049.2013.843025","volume":"30","author":"G Liebezeit","year":"2013","unstructured":"Liebezeit G, Liebezeit E (2013) Non-pollen particulates in honey and sugar. Food Addit Contam Part Chem Anal Control Expo Risk Assess 30(12):2136\u20132140. https:\/\/doi.org\/10.1080\/19440049.2013.843025","journal-title":"Food Addit Contam Part Chem Anal Control Expo Risk Assess"},{"issue":"7857","key":"4712_CR94","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1038\/d41586-021-01143-3","volume":"593","author":"X Lim","year":"2021","unstructured":"Lim X (2021) Microplastics are everywhere - but are they harmful? Nature 593(7857):22\u201325. https:\/\/doi.org\/10.1038\/d41586-021-01143-3","journal-title":"Nature"},{"key":"4712_CR95","doi-asserted-by":"publisher","first-page":"462","DOI":"10.1016\/j.scitotenv.2019.04.110","volume":"675","author":"K Liu","year":"2019","unstructured":"Liu K, Wang X, Fang T, Xu P, Zhu L, Li D (2019) Source and potential risk assessment of suspended atmospheric microplastics in Shanghai. Sci Total Environ 675:462\u2013471. https:\/\/doi.org\/10.1016\/j.scitotenv.2019.04.110","journal-title":"Sci Total Environ"},{"key":"4712_CR96","doi-asserted-by":"publisher","first-page":"158699","DOI":"10.1016\/j.scitotenv.2022.158699","volume":"854","author":"S Liu","year":"2023","unstructured":"Liu S, Guo J, Liu X, Yang R, Wang H, Sun Y, Chen B, Dong R (2023) Detection of various microplastics in placentas, meconium, infant feces, breastmilk and infant formula: A pilot prospective study. Sci Total Environ 854:158699. https:\/\/doi.org\/10.1016\/j.scitotenv.2022.158699","journal-title":"Sci Total Environ"},{"issue":"7","key":"4712_CR98","doi-asserted-by":"publisher","first-page":"4054","DOI":"10.1021\/acs.est.6b00183","volume":"50","author":"Y Lu","year":"2016","unstructured":"Lu Y, Zhang Y, Deng Y, Jiang W, Zhao Y, Geng J, Ding L, Ren H (2016) Uptake and accumulation of polystyrene microplastics in zebrafish (Danio rerio) and toxic effects in liver. Environ Sci Technol 50(7):4054\u20134060. https:\/\/doi.org\/10.1021\/acs.est.6b00183","journal-title":"Environ Sci Technol"},{"key":"4712_CR97","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1016\/j.scitotenv.2018.03.051","volume":"631\u2013632","author":"L Lu","year":"2018","unstructured":"Lu L, Wan Z, Luo T, Fu Z, Jin Y (2018) Polystyrene microplastics induce gut microbiota dysbiosis and hepatic lipid metabolism disorder in mice. Sci Total Environ 631\u2013632:449\u2013458. https:\/\/doi.org\/10.1016\/j.scitotenv.2018.03.051","journal-title":"Sci Total Environ"},{"key":"4712_CR99","doi-asserted-by":"publisher","first-page":"118857","DOI":"10.1016\/j.envpol.2022.118857","volume":"298","author":"Y Luo","year":"2022","unstructured":"Luo Y, Al Amin M, Gibson CT, Chuah C, Tang Y, Naidu R, Fang C (2022) Raman imaging of microplastics and nanoplastics generated by cutting PVC pipe. Environ Pollut 298:118857. https:\/\/doi.org\/10.1016\/j.envpol.2022.118857","journal-title":"Environ Pollut"},{"key":"4712_CR100","doi-asserted-by":"publisher","unstructured":"Maddah H (2016) Polypropylene as a promising plastic: A review. 2163 \u2013 1352 2016(1\u201311). https:\/\/doi.org\/10.5923\/j.ajps.20160601.01","DOI":"10.5923\/j.ajps.20160601.01"},{"key":"4712_CR101","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1289\/ehp.814185","volume":"41","author":"C Maltoni","year":"1981","unstructured":"Maltoni C, Lodi P (1981) Results of sputum, cytology among workers exposed to vinyl chloride monomer and to poly(vinyl chloride). Environ Health Perspect 41:85\u201388. https:\/\/doi.org\/10.1289\/ehp.814185","journal-title":"Environ Health Perspect"},{"issue":"1","key":"4712_CR102","doi-asserted-by":"publisher","first-page":"10772","DOI":"10.1038\/s41598-017-11079-2","volume":"7","author":"J Martin","year":"2017","unstructured":"Martin J, Lusher A, Thompson RC, Morley A (2017) The deposition and accumulation of microplastics in marine sediments and bottom water from the Irish continental shelf. Sci Rep 7(1):10772. https:\/\/doi.org\/10.1038\/s41598-017-11079-2","journal-title":"Sci Rep"},{"issue":"19","key":"4712_CR103","doi-asserted-by":"publisher","first-page":"5296","DOI":"10.1021\/acs.jafc.0c01209","volume":"68","author":"R Mercogliano","year":"2020","unstructured":"Mercogliano R, Avio CG, Regoli F, Anastasio A, Colavita G, Santonicola S (2020) Occurrence of microplastics in commercial seafood under the perspective of the human food Chain. A review. J Agric Food Chem 68(19):5296\u20135301. https:\/\/doi.org\/10.1021\/acs.jafc.0c01209","journal-title":"J Agric Food Chem"},{"key":"4712_CR104","doi-asserted-by":"publisher","first-page":"125610","DOI":"10.1016\/j.polymer.2022.125610","volume":"266","author":"C Mijangos","year":"2022","unstructured":"Mijangos C, Calafel I, Santamar\u00eda A (2022) Poly(vinyl chloride), a historical polymer still evolving. Polymer 266:125610. https:\/\/doi.org\/10.1016\/j.polymer.2022.125610","journal-title":"Polymer"},{"issue":"4","key":"4712_CR105","doi-asserted-by":"publisher","first-page":"102006","DOI":"10.1016\/j.jksus.2022.102006","volume":"34","author":"G Nabi","year":"2022","unstructured":"Nabi G, Ahmad S, Ullah S, Zada S, Sarfraz M, Guo X, Ismail M, Wanghe K (2022) The adverse health effects of increasing microplastic pollution on aquatic mammals. J King Saud Univ - Sci 34(4):102006. https:\/\/doi.org\/10.1016\/j.jksus.2022.102006","journal-title":"J King Saud Univ - Sci"},{"key":"4712_CR106","doi-asserted-by":"publisher","first-page":"100487","DOI":"10.1016\/j.hazadv.2024.100487","volume":"16","author":"A Nawab","year":"2024","unstructured":"Nawab A, Ahmad M, Khan MT, Nafees M, Khan I, Ihsanullah I (2024) Human exposure to microplastics: A review on exposure routes and public health impacts. J Hazard Mater Adv 16:100487. https:\/\/doi.org\/10.1016\/j.hazadv.2024.100487","journal-title":"J Hazard Mater Adv"},{"key":"4712_CR107","doi-asserted-by":"publisher","first-page":"100437","DOI":"10.1016\/j.envadv.2023.100437","volume":"13","author":"AO Nosova","year":"2023","unstructured":"Nosova AO, Uspenskaya MV (2023) Ecotoxicological effects and detection features of Polyvinyl chloride microplastics in soils: A review. Environ Adv 13:100437. https:\/\/doi.org\/10.1016\/j.envadv.2023.100437","journal-title":"Environ Adv"},{"key":"4712_CR108","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1071\/EN15069","volume":"12","author":"S Oberbeckmann","year":"2015","unstructured":"Oberbeckmann S, L\u00f6der M, Labrenz M (2015) Marine microplastic-associated biofilms \u2013 a review. Environ Chem 12:551\u2013562. https:\/\/doi.org\/10.1071\/EN15069","journal-title":"Environ Chem"},{"issue":"6\u20137","key":"4712_CR109","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1080\/08958370490439597","volume":"16","author":"G Oberd\u00f6rster","year":"2004","unstructured":"Oberd\u00f6rster G, Sharp Z, Atudorei V, Elder A, Gelein R, Kreyling W, Cox C (2004) Translocation of inhaled ultrafine particles to the brain. Inhal Toxicol 16(6\u20137):437\u2013445. https:\/\/doi.org\/10.1080\/08958370490439597","journal-title":"Inhal Toxicol"},{"issue":"6","key":"4712_CR110","doi-asserted-by":"publisher","first-page":"981","DOI":"10.1016\/j.nano.2011.12.001","volume":"8","author":"C Oslakovic","year":"2012","unstructured":"Oslakovic C, Cedervall T, Linse S, Dahlb\u00e4ck B (2012) Polystyrene nanoparticles affecting blood coagulation. Nanomedicine 8(6):981\u2013986. https:\/\/doi.org\/10.1016\/j.nano.2011.12.001","journal-title":"Nanomedicine"},{"issue":"3","key":"4712_CR111","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1006\/smim.1999.0171","volume":"11","author":"RL Owen","year":"1999","unstructured":"Owen RL (1999) Uptake and transport of intestinal macromolecules and microorganisms by M cells in peyer\u2019s patches\u2013a personal and historical perspective. Semin Immunol 11(3):157\u2013163. https:\/\/doi.org\/10.1006\/smim.1999.0171","journal-title":"Semin Immunol"},{"issue":"4","key":"4712_CR112","doi-asserted-by":"publisher","first-page":"e0123297","DOI":"10.1371\/journal.pone.0123297","volume":"10","author":"V Paget","year":"2015","unstructured":"Paget V, Dekali S, Kortulewski T, Grall R, Gamez C, Blazy K, Aguerre-Chariol O, Chevillard S, Braun A, Rat P, Lacroix G (2015) Specific uptake and genotoxicity induced by polystyrene nanobeads with distinct surface chemistry on human lung epithelial cells and macrophages. PLoS ONE 10(4):e0123297. https:\/\/doi.org\/10.1371\/journal.pone.0123297","journal-title":"PLoS ONE"},{"issue":"5","key":"4712_CR113","first-page":"419","volume":"7","author":"JL Pauly","year":"1998","unstructured":"Pauly JL, Stegmeier SJ, Allaart HA, Cheney RT, Zhang PJ, Mayer AG, Streck RJ (1998) Inhaled cellulosic and plastic fibers found in human lung tissue. Cancer Epidemiol Biomarkers Prev 7(5):419\u2013428","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"issue":"2","key":"4712_CR114","doi-asserted-by":"publisher","first-page":"264","DOI":"10.3390\/biomedicines11020264","volume":"11","author":"E Persiani","year":"2023","unstructured":"Persiani E, Cecchettini A, Ceccherini E, Gisone I, Morales MA, Vozzi F (2023) Microplastics: A matter of the heart (and vascular System). Biomedicines 11(2):264. https:\/\/www.mdpi.com\/2227-9059\/11\/2\/264","journal-title":"Biomedicines"},{"issue":"42","key":"4712_CR116","doi-asserted-by":"publisher","first-page":"59439","DOI":"10.1007\/s11356-021-12467-y","volume":"28","author":"M Pittroff","year":"2021","unstructured":"Pittroff M, M\u00fcller YK, Witzig CS, Scheurer M, Storck FR, Zumb\u00fclte N (2021) Microplastic analysis in drinking water based on fractionated filtration sampling and Raman microspectroscopy. Environ Sci Pollut Res Int 28(42):59439\u201359451. https:\/\/doi.org\/10.1007\/s11356-021-12467-y","journal-title":"Environ Sci Pollut Res Int"},{"key":"4712_CR117","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1016\/j.envpol.2017.11.043","volume":"234","author":"JC Prata","year":"2018","unstructured":"Prata JC (2018a) Airborne microplastics: consequences to human health? Environ Pollut 234:115\u2013126. https:\/\/doi.org\/10.1016\/j.envpol.2017.11.043","journal-title":"Environ Pollut"},{"key":"4712_CR118","doi-asserted-by":"publisher","unstructured":"Prata JC (2018b) Airborne microplastics: consequences to human health? Environ pollut. 234:115\u2013126. https:\/\/doi.org\/10.1016\/j.envpol.2017.11.043","DOI":"10.1016\/j.envpol.2017.11.043"},{"key":"4712_CR119","doi-asserted-by":"publisher","first-page":"1","DOI":"10.14419\/ijh.v6i1.8655","volume":"6","author":"R Proshad","year":"2018","unstructured":"Proshad R, Kormoker T, Islam M, Haque M, Rahman M, Mithu M (2018) Toxic effects of plastic on human health and environment: A consequences of health risk assessment in Bangladesh. Int J Health 6:1\u20135. https:\/\/doi.org\/10.14419\/ijh.v6i1.8655","journal-title":"Int J Health"},{"key":"4712_CR120","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1146\/annurev-genet-022020-023434","volume":"54","author":"N Punjani","year":"2020","unstructured":"Punjani N, Lamb DJ (2020) Canary in the coal mine? Male infertility as a marker of overall health. Annu Rev Genet 54:465\u2013486. https:\/\/doi.org\/10.1146\/annurev-genet-022020-023434","journal-title":"Annu Rev Genet"},{"key":"4712_CR121","doi-asserted-by":"publisher","first-page":"106274","DOI":"10.1016\/j.envint.2020.106274","volume":"146","author":"A Ragusa","year":"2021","unstructured":"Ragusa A, Svelato A, Santacroce C, Catalano P, Notarstefano V, Carnevali O, Papa F, Rongioletti MCA, Baiocco F, Draghi S, Amore E, Rinaldo D, Matta M, Giorgini E (2021) Plasticenta: first evidence of microplastics in human placenta. Environ Int 146:106274. https:\/\/doi.org\/10.1016\/j.envint.2020.106274","journal-title":"Environ Int"},{"key":"4712_CR122","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1016\/j.envres.2017.12.019","volume":"162","author":"S Rainieri","year":"2018","unstructured":"Rainieri S, Conlledo N, Larsen BK, Granby K, Barranco A (2018) Combined effects of microplastics and chemical contaminants on the organ toxicity of zebrafish (Danio rerio). Environ Res 162:135\u2013143. https:\/\/doi.org\/10.1016\/j.envres.2017.12.019","journal-title":"Environ Res"},{"issue":"12","key":"4712_CR123","doi-asserted-by":"publisher","first-page":"2132","DOI":"10.1039\/d4em00262h","volume":"26","author":"B Rani-Borges","year":"2024","unstructured":"Rani-Borges B, Arena MVN, Gomes IN, Lins L, Cestaro LSC, Pomp\u00eao M, Ando RA, Alves-Dos-Santos I, Toppa RH, Martines MR, Queiroz LG (2024) More than just sweet: current insights into microplastics in honey products and a case study of Melipona quadrifasciata honey. Environ Sci Process Impacts 26(12):2132\u20132144. https:\/\/doi.org\/10.1039\/d4em00262h","journal-title":"Environ Sci Process Impacts"},{"issue":"8","key":"4712_CR124","doi-asserted-by":"publisher","first-page":"1231","DOI":"10.1016\/j.marpolbul.2010.03.021","volume":"60","author":"CA Ribic","year":"2010","unstructured":"Ribic CA, Sheavly SB, Rugg DJ, Erdmann ES (2010) Trends and drivers of marine debris on the Atlantic Coast of the united States 1997\u20132007. Mar Pollut Bull 60(8):1231\u20131242. https:\/\/doi.org\/10.1016\/j.marpolbul.2010.03.021","journal-title":"Mar Pollut Bull"},{"issue":"6498","key":"4712_CR125","doi-asserted-by":"publisher","first-page":"1430","DOI":"10.1126\/science.abb5979","volume":"368","author":"MC Rillig","year":"2020","unstructured":"Rillig MC, Lehmann A (2020) Microplastic in terrestrial ecosystems. Science 368(6498):1430\u20131431. https:\/\/doi.org\/10.1126\/science.abb5979","journal-title":"Science"},{"key":"4712_CR126","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1016\/j.scitotenv.2011.12.030","volume":"417\u2013418","author":"L Roes","year":"2012","unstructured":"Roes L, Patel MK, Worrell E, Ludwig C (2012) Preliminary evaluation of risks related to waste incineration of polymer nanocomposites. Sci Total Environ 417\u2013418:76\u201386. https:\/\/doi.org\/10.1016\/j.scitotenv.2011.12.030","journal-title":"Sci Total Environ"},{"key":"4712_CR127","doi-asserted-by":"publisher","first-page":"121175","DOI":"10.1016\/j.biomaterials.2021.121175","volume":"278","author":"A Roshanzadeh","year":"2021","unstructured":"Roshanzadeh A, Oyunbaatar NE, Ganjbakhsh SE, Park S, Kim DS, Kanade PP, Lee S, Lee DW, Kim ES (2021) Exposure to nanoplastics impairs collective contractility of neonatal cardiomyocytes under electrical synchronization. Biomaterials 278:121175. https:\/\/doi.org\/10.1016\/j.biomaterials.2021.121175","journal-title":"Biomaterials"},{"issue":"2","key":"4712_CR130","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1080\/10937404.2019.1700598","volume":"23","author":"L Rubio","year":"2020","unstructured":"Rubio L, Marcos R, Hern\u00e1ndez A (2020) Potential adverse health effects of ingested micro- and nanoplastics on humans. Lessons learned from in vivo and in vitro mammalian models. J Toxicol Environ Health B Crit Rev 23(2):51\u201368. https:\/\/doi.org\/10.1080\/10937404.2019.1700598","journal-title":"J Toxicol Environ Health B Crit Rev"},{"key":"4712_CR129","doi-asserted-by":"publisher","first-page":"1174","DOI":"10.3390\/ijerph19031174","volume":"19","author":"C Rubio","year":"2022","unstructured":"Rubio C, Vega A, Paz S, Guti\u00e9rrez S, Carrascosa-Iruzubieta A, C., Hardisson A (2022) Microplastics as emerging food contaminants: A challenge for food safety. Int J Environ Res Public Health 19:1174. https:\/\/doi.org\/10.3390\/ijerph19031174","journal-title":"Int J Environ Res Public Health"},{"key":"4712_CR131","doi-asserted-by":"publisher","unstructured":"Saito A, Horie M, Nagase T (2018) TGF-\u03b2 signaling in lung health and disease. Int J Mol Sci 19(8). https:\/\/doi.org\/10.3390\/ijms19082460","DOI":"10.3390\/ijms19082460"},{"issue":"4","key":"4712_CR132","doi-asserted-by":"publisher","first-page":"197","DOI":"10.4161\/derm.1.4.9501","volume":"1","author":"M Schneider","year":"2009","unstructured":"Schneider M, Stracke F, Hansen S, Schaefer UF (2009) Nanoparticles and their interactions with the dermal barrier. Dermatoendocrinol 1(4):197\u2013206. https:\/\/doi.org\/10.4161\/derm.1.4.9501","journal-title":"Dermatoendocrinol"},{"issue":"6","key":"4712_CR133","doi-asserted-by":"publisher","first-page":"1106","DOI":"10.1161\/01.Hyp.0000100444.71069.73","volume":"42","author":"EB Schroeder","year":"2003","unstructured":"Schroeder EB, Liao D, Chambless LE, Prineas RJ, Evans GW, Heiss G (2003) Hypertension, blood pressure, and heart rate variability: the atherosclerosis risk in communities (ARIC) study. Hypertension 42(6):1106\u20131111. https:\/\/doi.org\/10.1161\/01.Hyp.0000100444.71069.73","journal-title":"Hypertension"},{"issue":"9","key":"4712_CR134","doi-asserted-by":"publisher","first-page":"729","DOI":"10.1038\/s41565-020-0762-x","volume":"15","author":"F Schwab","year":"2020","unstructured":"Schwab F, Rothen-Rutishauser B, Petri-Fink A (2020) When plants and plastic interact. Nat Nanotechnol 15(9):729\u2013730. https:\/\/doi.org\/10.1038\/s41565-020-0762-x","journal-title":"Nat Nanotechnol"},{"key":"4712_CR135","doi-asserted-by":"publisher","unstructured":"Selke S, Hernandez RJ (2001) Packaging: Polymers for Containers. In (pp. 6646\u20136652). https:\/\/doi.org\/10.1016\/B0-08-043152-6\/01175-X","DOI":"10.1016\/B0-08-043152-6\/01175-X"},{"key":"4712_CR136","doi-asserted-by":"publisher","first-page":"134261","DOI":"10.1016\/j.chemosphere.2022.134261","volume":"298","author":"S Shan","year":"2022","unstructured":"Shan S, Zhang Y, Zhao H, Zeng T, Zhao X (2022) Polystyrene nanoplastics penetrate across the blood-brain barrier and induce activation of microglia in the brain of mice. Chemosphere 298:134261. https:\/\/doi.org\/10.1016\/j.chemosphere.2022.134261","journal-title":"Chemosphere"},{"issue":"4","key":"4712_CR137","doi-asserted-by":"publisher","first-page":"533","DOI":"10.2217\/nnm.10.25","volume":"5","author":"HS Sharma","year":"2010","unstructured":"Sharma HS, Sharma A (2010) Conference scene: nanoneuroprotection and nanoneurotoxicity: recent progress and future perspectives. Nanomed (Lond) 5(4):533\u2013537. https:\/\/doi.org\/10.2217\/nnm.10.25","journal-title":"Nanomed (Lond)"},{"key":"4712_CR138","doi-asserted-by":"publisher","first-page":"136168","DOI":"10.1016\/j.jhazmat.2024.136168","volume":"480","author":"C Sheng","year":"2024","unstructured":"Sheng C, Wang G, Liu Z, Zheng Y, Zhao Z, Tang D, Li W, Li A, Zong Q, Zhou R, Hou X, Yao M, Zhou Z (2024) Polystyrene nanoplastics enhance thrombosis through adsorption of plasma proteins. J Hazard Mater 480:136168. https:\/\/doi.org\/10.1016\/j.jhazmat.2024.136168","journal-title":"J Hazard Mater"},{"key":"4712_CR139","doi-asserted-by":"publisher","first-page":"128109","DOI":"10.1016\/j.jhazmat.2021.128109","volume":"429","author":"W Shi","year":"2022","unstructured":"Shi W, Cao Y, Chai X, Zhao Q, Geng Y, Liu D, Tian S (2022a) Potential health risks of the interaction of microplastics and lung surfactant. J Hazard Mater 429:128109. https:\/\/doi.org\/10.1016\/j.jhazmat.2021.128109","journal-title":"J Hazard Mater"},{"key":"4712_CR140","doi-asserted-by":"publisher","first-page":"106049","DOI":"10.1016\/j.aquatox.2021.106049","volume":"242","author":"W Shi","year":"2022","unstructured":"Shi W, Sun S, Han Y, Tang Y, Zhou W, Zhang W, Du X, Huang L, Liu G (2022b) Microplastics hamper the fertilization success of a broadcast spawning bivalve through reducing gamete collision and gamete fusion efficiency. Aquat Toxicol 242:106049. https:\/\/doi.org\/10.1016\/j.aquatox.2021.106049","journal-title":"Aquat Toxicol"},{"issue":"3","key":"4712_CR141","doi-asserted-by":"publisher","first-page":"597","DOI":"10.1113\/jphysiol.2008.165902","volume":"587","author":"AE Simms","year":"2009","unstructured":"Simms AE, Paton JF, Pickering AE, Allen AM (2009) Amplified respiratory-sympathetic coupling in the spontaneously hypertensive rat: does it contribute to hypertension? J Physiol 587(3):597\u2013610. https:\/\/doi.org\/10.1113\/jphysiol.2008.165902","journal-title":"J Physiol"},{"issue":"3","key":"4712_CR142","doi-asserted-by":"publisher","first-page":"560","DOI":"10.1016\/j.fertnstert.2022.05.018","volume":"118","author":"M Snow","year":"2022","unstructured":"Snow M, Vranich TM, Perin J, Trent M (2022) Estimates of infertility in the united states: 1995\u20132019. Fertil Steril 118(3):560\u2013567. https:\/\/doi.org\/10.1016\/j.fertnstert.2022.05.018","journal-title":"Fertil Steril"},{"key":"4712_CR143","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/S1464-391X(04)00135-7","volume":"6","author":"V Steukers","year":"2004","unstructured":"Steukers V, Kroon S, Drohmann D (2004) Flame retardants: European union risk assessments update. Plast Addit Compd 6:26\u201329. https:\/\/doi.org\/10.1016\/S1464-391X(04)00135-7","journal-title":"Plast Addit Compd"},{"issue":"1","key":"4712_CR144","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1038\/s41565-021-00998-x","volume":"17","author":"Y Su","year":"2022","unstructured":"Su Y, Hu X, Tang H, Lu K, Li H, Liu S, Xing B, Ji R (2022) Steam disinfection releases micro(nano)plastics from silicone-rubber baby teats as examined by optical photothermal infrared microspectroscopy. Nat Nanotechnol 17(1):76\u201385. https:\/\/doi.org\/10.1038\/s41565-021-00998-x","journal-title":"Nat Nanotechnol"},{"issue":"1","key":"4712_CR145","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1016\/j.advms.2019.12.008","volume":"65","author":"M Szamatowicz","year":"2020","unstructured":"Szamatowicz M, Szamatowicz J (2020) Proven and unproven methods for diagnosis and treatment of infertility. Adv Med Sci 65(1):93\u201396. https:\/\/doi.org\/10.1016\/j.advms.2019.12.008","journal-title":"Adv Med Sci"},{"issue":"19","key":"4712_CR146","doi-asserted-by":"publisher","first-page":"12285","DOI":"10.1021\/acs.est.0c02608","volume":"54","author":"H Tan","year":"2020","unstructured":"Tan H, Yue T, Xu Y, Zhao J, Xing B (2020) Microplastics reduce lipid digestion in simulated human Gastrointestinal system. Environ Sci Technol 54(19):12285\u201312294. https:\/\/doi.org\/10.1021\/acs.est.0c02608","journal-title":"Environ Sci Technol"},{"issue":"Pt 3","key":"4712_CR148","doi-asserted-by":"publisher","first-page":"135198","DOI":"10.1016\/j.chemosphere.2022.135198","volume":"303","author":"M Tarasco","year":"2022","unstructured":"Tarasco M, Gavaia PJ, Bensimon-Brito A, Cordeli\u00e8res FP, Santos T, Martins G, de Castro DT, Silva N, Cabrita E, Bebianno MJ, Stainier DYR, Cancela ML, Laiz\u00e9 V (2022) Effects of pristine or contaminated polyethylene microplastics on zebrafish development. Chemosphere 303(Pt 3):135198. https:\/\/doi.org\/10.1016\/j.chemosphere.2022.135198","journal-title":"Chemosphere"},{"key":"4712_CR149","doi-asserted-by":"publisher","first-page":"115577","DOI":"10.1016\/j.watres.2020.115577","volume":"173","author":"A Turner","year":"2020","unstructured":"Turner A, Holmes L, Thompson RC, Fisher AS (2020) Metals and marine microplastics: adsorption from the environment versus addition during manufacture, exemplified with lead. Water Res 173:115577. https:\/\/doi.org\/10.1016\/j.watres.2020.115577","journal-title":"Water Res"},{"key":"4712_CR150","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/j.envpol.2014.06.010","volume":"193","author":"L Van Cauwenberghe","year":"2014","unstructured":"Van Cauwenberghe L, Janssen CR (2014) Microplastics in bivalves cultured for human consumption. Environ Pollut 193:65\u201370. https:\/\/doi.org\/10.1016\/j.envpol.2014.06.010","journal-title":"Environ Pollut"},{"issue":"4","key":"4712_CR151","doi-asserted-by":"publisher","first-page":"300","DOI":"10.1038\/s41565-019-0424-z","volume":"14","author":"S Wagner","year":"2019","unstructured":"Wagner S, Reemtsma T (2019) Things we know and don\u2019t know about nanoplastic in the environment. Nat Nanotechnol 14(4):300\u2013301. https:\/\/doi.org\/10.1038\/s41565-019-0424-z","journal-title":"Nat Nanotechnol"},{"key":"4712_CR152","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1289\/ehp.835261","volume":"52","author":"JK Wagoner","year":"1983","unstructured":"Wagoner JK (1983) Toxicity of vinyl chloride and poly(vinyl chloride): a critical review. Environ Health Perspect 52:61\u201366. https:\/\/doi.org\/10.1289\/ehp.835261","journal-title":"Environ Health Perspect"},{"key":"4712_CR153","doi-asserted-by":"publisher","unstructured":"Wainkwa Chia R, Lee J-Y, Kim H, Jang J (2021) Microplastic pollution in soil and groundwater: a review. Environ Chem Lett 19. https:\/\/doi.org\/10.1007\/s10311-021-01297-6","DOI":"10.1007\/s10311-021-01297-6"},{"issue":"Pt B","key":"4712_CR155","doi-asserted-by":"publisher","first-page":"113024","DOI":"10.1016\/j.envpol.2019.113024","volume":"254","author":"J Wang","year":"2019","unstructured":"Wang J, Li Y, Lu L, Zheng M, Zhang X, Tian H, Wang W, Ru S (2019) Polystyrene microplastics cause tissue damages, sex-specific reproductive disruption and transgenerational effects in marine Medaka (Oryzias melastigma). Environ Pollut 254(Pt B):113024. https:\/\/doi.org\/10.1016\/j.envpol.2019.113024","journal-title":"Environ Pollut"},{"key":"4712_CR154","doi-asserted-by":"publisher","first-page":"119129","DOI":"10.1016\/j.watres.2022.119129","volume":"225","author":"C Wang","year":"2022","unstructured":"Wang C, O\u2019Connor D, Wang L, Wu WM, Luo J, Hou D (2022) Microplastics in urban runoff: global occurrence and fate. Water Res 225:119129. https:\/\/doi.org\/10.1016\/j.watres.2022.119129","journal-title":"Water Res"},{"issue":"5","key":"4712_CR156","doi-asserted-by":"publisher","first-page":"935","DOI":"10.1002\/tox.23095","volume":"36","author":"J Wei","year":"2021","unstructured":"Wei J, Wang X, Liu Q, Zhou N, Zhu S, Li Z, Li X, Yao J, Zhang L (2021) The impact of polystyrene microplastics on cardiomyocytes pyroptosis through NLRP3\/Caspase-1 signaling pathway and oxidative stress in Wistar rats. Environ Toxicol 36(5):935\u2013944. https:\/\/doi.org\/10.1002\/tox.23095","journal-title":"Environ Toxicol"},{"issue":"4","key":"4712_CR157","doi-asserted-by":"publisher","first-page":"eaap8060","DOI":"10.1126\/sciadv.aap8060","volume":"4","author":"N Weithmann","year":"2018","unstructured":"Weithmann N, M\u00f6ller JN, L\u00f6der MGJ, Piehl S, Laforsch C, Freitag R (2018) Organic fertilizer as a vehicle for the entry of microplastic into the environment. Sci Adv 4(4):eaap8060. https:\/\/doi.org\/10.1126\/sciadv.aap8060","journal-title":"Sci Adv"},{"issue":"12","key":"4712_CR158","doi-asserted-by":"publisher","first-page":"6634","DOI":"10.1021\/acs.est.7b00423","volume":"51","author":"SL Wright","year":"2017","unstructured":"Wright SL, Kelly FJ (2017) Plastic and human health: A micro issue? Environ Sci Technol 51(12):6634\u20136647. https:\/\/doi.org\/10.1021\/acs.est.7b00423","journal-title":"Environ Sci Technol"},{"key":"4712_CR159","doi-asserted-by":"publisher","first-page":"129361","DOI":"10.1016\/j.jhazmat.2022.129361","volume":"437","author":"P Wu","year":"2022","unstructured":"Wu P, Lin S, Cao G, Wu J, Jin H, Wang C, Wong MH, Yang Z, Cai Z (2022) Absorption, distribution, metabolism, excretion and toxicity of microplastics in the human body and health implications. J Hazard Mater 437:129361. https:\/\/doi.org\/10.1016\/j.jhazmat.2022.129361","journal-title":"J Hazard Mater"},{"key":"4712_CR160","doi-asserted-by":"publisher","first-page":"110133","DOI":"10.1016\/j.ecoenv.2019.110133","volume":"190","author":"X Xie","year":"2020","unstructured":"Xie X, Deng T, Duan J, Xie J, Yuan J, Chen M (2020) Exposure to polystyrene microplastics causes reproductive toxicity through oxidative stress and activation of the p38 MAPK signaling pathway. Ecotoxicol Environ Saf 190:110133. https:\/\/doi.org\/10.1016\/j.ecoenv.2019.110133","journal-title":"Ecotoxicol Environ Saf"},{"key":"4712_CR161","doi-asserted-by":"publisher","first-page":"133794","DOI":"10.1016\/j.scitotenv.2019.133794","volume":"694","author":"M Xu","year":"2019","unstructured":"Xu M, Halimu G, Zhang Q, Song Y, Fu X, Li Y, Li Y, Zhang H (2019) Internalization and toxicity: A preliminary study of effects of nanoplastic particles on human lung epithelial cell. Sci Total Environ 694:133794. https:\/\/doi.org\/10.1016\/j.scitotenv.2019.133794","journal-title":"Sci Total Environ"},{"key":"4712_CR162","doi-asserted-by":"publisher","first-page":"131470","DOI":"10.1016\/j.jhazmat.2023.131470","volume":"454","author":"W Xu","year":"2023","unstructured":"Xu W, Yuan Y, Tian Y, Cheng C, Chen Y, Zeng L, Yuan Y, Li D, Zheng L, Luo T (2023) Oral exposure to polystyrene nanoplastics reduced male fertility and even caused male infertility by inducing testicular and sperm toxicities in mice. J Hazard Mater 454:131470. https:\/\/doi.org\/10.1016\/j.jhazmat.2023.131470","journal-title":"J Hazard Mater"},{"key":"4712_CR163","doi-asserted-by":"publisher","first-page":"703","DOI":"10.1016\/j.jhazmat.2018.12.048","volume":"366","author":"Y-F Yang","year":"2019","unstructured":"Yang Y-F, Chen C-Y, Lu T-H, Liao C-M (2019) Toxicity-based toxicokinetic\/toxicodynamic assessment for bioaccumulation of polystyrene microplastics in mice. J Hazard Mater 366:703\u2013713","journal-title":"J Hazard Mater"},{"key":"4712_CR164","doi-asserted-by":"crossref","unstructured":"Yee MS-L, Hii L-W, Looi CK, Lim W-M, Wong S-F, Kok Y-Y, Tan B-K, Wong C-Y, Leong C-O (2021) Impact of Microplastics and Nanoplastics on Human Health. Nanomaterials, 11(2), 496. https:\/\/www.mdpi.com\/2079-4991\/11\/2\/496","DOI":"10.3390\/nano11020496"},{"issue":"1","key":"4712_CR165","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1007\/s11154-019-09521-z","volume":"21","author":"B Yilmaz","year":"2020","unstructured":"Yilmaz B, Terekeci H, Sandal S, Kelestimur F (2020) Endocrine disrupting chemicals: exposure, effects on human health, mechanism of action, models for testing and strategies for prevention. Rev Endocr Metab Disord 21(1):127\u2013147. https:\/\/doi.org\/10.1007\/s11154-019-09521-z","journal-title":"Rev Endocr Metab Disord"},{"key":"4712_CR166","doi-asserted-by":"publisher","first-page":"114941","DOI":"10.1016\/j.ecoenv.2023.114941","volume":"257","author":"L Zeng","year":"2023","unstructured":"Zeng L, Zhou C, Xu W, Huang Y, Wang W, Ma Z, Huang J, Li J, Hu L, Xue Y, Luo T, Zheng L (2023) The ovarian-related effects of polystyrene nanoplastics on human ovarian granulosa cells and female mice. Ecotoxicol Environ Saf 257:114941. https:\/\/doi.org\/10.1016\/j.ecoenv.2023.114941","journal-title":"Ecotoxicol Environ Saf"},{"issue":"13","key":"4712_CR167","doi-asserted-by":"publisher","first-page":"7137","DOI":"10.1021\/es401288x","volume":"47","author":"ER Zettler","year":"2013","unstructured":"Zettler ER, Mincer TJ, Amaral-Zettler LA (2013) Life in the plastisphere: microbial communities on plastic marine debris. Environ Sci Technol 47(13):7137\u20137146. https:\/\/doi.org\/10.1021\/es401288x","journal-title":"Environ Sci Technol"},{"key":"4712_CR168","doi-asserted-by":"publisher","first-page":"140638","DOI":"10.1016\/j.scitotenv.2020.140638","volume":"743","author":"R Zhang","year":"2020","unstructured":"Zhang R, Wang M, Chen X, Yang C, Wu L (2020) Combined toxicity of microplastics and cadmium on the zebrafish embryos (Danio rerio). Sci Total Environ 743:140638. https:\/\/doi.org\/10.1016\/j.scitotenv.2020.140638","journal-title":"Sci Total Environ"},{"key":"4712_CR170","doi-asserted-by":"publisher","first-page":"121482","DOI":"10.1016\/j.envpol.2023.121482","volume":"327","author":"Y Zhang","year":"2023","unstructured":"Zhang Y, Wang X, Zhao Y, Zhao J, Yu T, Yao Y, Zhao R, Yu R, Liu J, Su J (2023) Reproductive toxicity of microplastics in female mice and their offspring from induction of oxidative stress. Environ Pollut 327:121482. https:\/\/doi.org\/10.1016\/j.envpol.2023.121482","journal-title":"Environ Pollut"},{"key":"4712_CR169","doi-asserted-by":"publisher","first-page":"175881","DOI":"10.1016\/j.scitotenv.2024.175881","volume":"952","author":"S Zhang","year":"2024","unstructured":"Zhang S, Zhang H, Li Y, Sun Z, Chen Y (2024) Recent advances on transport and transformation mechanism of nanoplastics in lung cells. Sci Total Environ 952:175881. https:\/\/doi.org\/10.1016\/j.scitotenv.2024.175881","journal-title":"Sci Total Environ"},{"key":"4712_CR171","doi-asserted-by":"publisher","first-page":"139145","DOI":"10.1016\/j.scitotenv.2020.139145","volume":"730","author":"C Zhao","year":"2020","unstructured":"Zhao C, Wang Y, Su Z, Pu W, Niu M, Song S, Wei L, Ding Y, Xu L, Tian M, Wang H (2020) Respiratory exposure to PM2.5 soluble extract disrupts mucosal barrier function and promotes the development of experimental asthma. Sci Total Environ 730:139145. https:\/\/doi.org\/10.1016\/j.scitotenv.2020.139145","journal-title":"Sci Total Environ"},{"key":"4712_CR172","doi-asserted-by":"publisher","first-page":"116818","DOI":"10.1016\/j.ecoenv.2024.116818","volume":"283","author":"J Zhao","year":"2024","unstructured":"Zhao J, Zhang H, Shi L, Jia Y, Sheng H (2024) Detection and quantification of microplastics in various types of human tumor tissues. Ecotoxicol Environ Saf 283:116818. https:\/\/doi.org\/10.1016\/j.ecoenv.2024.116818","journal-title":"Ecotoxicol Environ Saf"},{"issue":"14","key":"4712_CR175","doi-asserted-by":"publisher","first-page":"2681","DOI":"10.1007\/s00018-019-03101-9","volume":"76","author":"R Zhou","year":"2019","unstructured":"Zhou R, Wu J, Liu B, Jiang Y, Chen W, Li J, He Q, He Z (2019) The roles and mechanisms of Leydig cells and myoid cells in regulating spermatogenesis. Cell Mol Life Sci 76(14):2681\u20132695. https:\/\/doi.org\/10.1007\/s00018-019-03101-9","journal-title":"Cell Mol Life Sci"},{"key":"4712_CR174","doi-asserted-by":"publisher","first-page":"107220","DOI":"10.1016\/j.envint.2022.107220","volume":"163","author":"L Zhou","year":"2022","unstructured":"Zhou L, Yu Z, Xia Y, Cheng S, Gao J, Sun W, Jiang X, Zhang J, Mao L, Qin X, Zou Z, Qiu J, Chen C (2022) Repression of autophagy leads to acrosome biogenesis disruption caused by a sub-chronic oral administration of polystyrene nanoparticles. Environ Int 163:107220. https:\/\/doi.org\/10.1016\/j.envint.2022.107220","journal-title":"Environ Int"},{"key":"4712_CR173","doi-asserted-by":"publisher","first-page":"130055","DOI":"10.1016\/j.jhazmat.2022.130055","volume":"442","author":"J Zhou","year":"2023","unstructured":"Zhou J, Jia R, Brown RW, Yang Y, Zeng Z, Jones DL, Zang H (2023) The long-term uncertainty of biodegradable mulch film residues and associated microplastics pollution on plant-soil health. J Hazard Mater 442:130055. https:\/\/doi.org\/10.1016\/j.jhazmat.2022.130055","journal-title":"J Hazard Mater"},{"key":"4712_CR176","doi-asserted-by":"publisher","first-page":"114818","DOI":"10.1016\/j.ecoenv.2023.114818","volume":"255","author":"L Zhu","year":"2023","unstructured":"Zhu L, Xie C, Chen L, Dai X, Zhou Y, Pan H, Tian K (2023a) Transport of microplastics in the body and interaction with biological barriers, and controlling of microplastics pollution. Ecotoxicol Environ Saf 255:114818. https:\/\/doi.org\/10.1016\/j.ecoenv.2023.114818","journal-title":"Ecotoxicol Environ Saf"},{"key":"4712_CR177","doi-asserted-by":"publisher","first-page":"107662","DOI":"10.1016\/j.envint.2022.107662","volume":"171","author":"X Zhu","year":"2023","unstructured":"Zhu X, Wang C, Duan X, Liang B, Xu G, E., Huang Z (2023b) Micro- and nanoplastics: A new cardiovascular risk factor? Environ Int 171:107662. https:\/\/doi.org\/10.1016\/j.envint.2022.107662","journal-title":"Environ Int"},{"issue":"1","key":"4712_CR178","doi-asserted-by":"publisher","first-page":"28","DOI":"10.14310\/horm.2002.1250","volume":"9","author":"TR Zoeller","year":"2010","unstructured":"Zoeller TR (2010) Environmental chemicals targeting thyroid. Horm (Athens) 9(1):28\u201340. https:\/\/doi.org\/10.14310\/horm.2002.1250","journal-title":"Horm (Athens)"},{"key":"4712_CR179","doi-asserted-by":"publisher","first-page":"e13503","DOI":"10.7717\/peerj.13503","volume":"10","author":"N Zolotova","year":"2022","unstructured":"Zolotova N, Kosyreva A, Dzhalilova D, Fokichev N, Makarova O (2022) Harmful effects of the microplastic pollution on animal health: a literature review. PeerJ 10:e13503. https:\/\/doi.org\/10.7717\/peerj.13503","journal-title":"PeerJ"}],"container-title":["3 Biotech"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13205-026-04712-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s13205-026-04712-3","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13205-026-04712-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T00:43:56Z","timestamp":1772757836000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s13205-026-04712-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,9]]},"references-count":171,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["4712"],"URL":"https:\/\/doi.org\/10.1007\/s13205-026-04712-3","relation":{},"ISSN":["2190-572X","2190-5738"],"issn-type":[{"value":"2190-572X","type":"print"},{"value":"2190-5738","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,9]]},"assertion":[{"value":"9 July 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 January 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 February 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"On behalf of all authors, I state that there is no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"88"}}