{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T20:33:08Z","timestamp":1760646788759,"version":"3.37.3"},"reference-count":61,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2018,2,20]],"date-time":"2018-02-20T00:00:00Z","timestamp":1519084800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/100000968","name":"American Heart Association","doi-asserted-by":"publisher","award":["5IRG22470015"],"award-info":[{"award-number":["5IRG22470015"]}],"id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cardiovasc Eng Tech"],"published-print":{"date-parts":[[2018,6]]},"DOI":"10.1007\/s13239-018-0342-5","type":"journal-article","created":{"date-parts":[[2018,2,20]],"date-time":"2018-02-20T19:46:17Z","timestamp":1519155977000},"page":"202-216","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Computational Investigation of a Self-Powered Fontan Circulation"],"prefix":"10.1007","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2425-6962","authenticated-orcid":false,"given":"Marcus W.","family":"Ni","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ray O.","family":"Prather","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanna","family":"Rodriguez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachel","family":"Quinn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo","family":"Divo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Fogel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alain J.","family":"Kassab","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William M.","family":"DeCampli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2018,2,20]]},"reference":[{"key":"342_CR1","doi-asserted-by":"publisher","first-page":"690","DOI":"10.1016\/S1010-7940(00)00593-5","volume":"18","author":"V Alexi-Meskishvili","year":"2000","unstructured":"Alexi-Meskishvili, V., S. Ovroutski, P. Ewert, I. Dahnert, F. Berger, P. Lange, and R. Hetzer. Optimal conduit size or extracardiac Fontan Operation. Eur. J. Cardiothorac. Surg. 18:690\u2013695, 2000.","journal-title":"Eur. J. Cardiothorac. Surg."},{"key":"342_CR2","doi-asserted-by":"publisher","first-page":"477","DOI":"10.1007\/s00246-007-9009-y","volume":"28","author":"E Bove","year":"2007","unstructured":"Bove, E., M. de Leval, F. Migliavacca, R. Balossino, and G. Dubini. Toward optimal hemodynamics: computer modeling of the Fontan circuit. Pediatr. Cardiol. 28:477\u2013481, 2007.","journal-title":"Pediatr. Cardiol."},{"key":"342_CR3","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1016\/j.jtcvs.2007.04.078","volume":"136","author":"E Bove","year":"2008","unstructured":"Bove, E., F. Migliavacca, M. de Leval, R. Balossino, G. Pennati, T. Lloyd, S. Khambadkone, T. Hsia, and G. Dubini. Use of mathematical modeling to compare and predict hemodynamics effects of the modified Blalock-Taussig and right ventricle-pulmonary artery shunts for hypoplastic left heart syndrome. J. Thorac. Cardiovasc. Surg. 136:312\u2013320, 2008.","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"342_CR4","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/0301-9322(83)90061-7","volume":"10","author":"A Brahim","year":"1984","unstructured":"Brahim, A., M. Prevost, and R. Bugarel. Momentum transfer in a vertical down flow liquid jet ejector: case of self gas aspiration and emulsion flow. Int. J. Multiphase Flow. 10:79\u201394, 1984.","journal-title":"Int. J. Multiphase Flow."},{"key":"342_CR5","unstructured":"CD-Adapco a Siemens Business, StarCCM\u00a0+\u00a011.04.010 User Guide, 2016"},{"key":"342_CR6","doi-asserted-by":"publisher","first-page":"1540","DOI":"10.1016\/j.athoracsur.2012.06.043","volume":"94","author":"A Ceballos","year":"2012","unstructured":"Ceballos, A., R. Argueta-Morales, E. Divo, R. Osorio, C. Caldarone, A. Kassab, and W. DeCampli. Computational analysis of hybrid norwood circulation with distal aortic arch obstruction and reverse Blalock-Taussig. Shunt Ann. Thorac. Surg. 94:1540\u20131550, 2012.","journal-title":"Shunt Ann. Thorac. Surg."},{"key":"342_CR7","doi-asserted-by":"crossref","unstructured":"Ceballos A, Divo E, Argueta-Morales R, Calderone C, Kassab A, and DeCampli W. A multi-scale CFD analysis of the hybrid norwood palliative treatment for hypoplastic left heart syndrome: effect of the reverse Blalock-Taussig shunt diameter. ASME 2013 IMECE, vol. 3B: Biomedical and Biotechnology Engineering. ASME paper number IMECE 2013-66856","DOI":"10.1115\/IMECE2013-66856"},{"issue":"3","key":"342_CR8","first-page":"323","volume":"94","author":"P Chungsomprasong","year":"2011","unstructured":"Chungsomprasong, P., J. Soongswang, A. Nana, K. Durongpisitkul, D. Loahaprasitiporn, C. Vijansorn, and S. Sriyodchartti. Medium and long-term outcomes of Fontan operation. J. Med. Assoc. Thai. 94(3):323\u2013330, 2011.","journal-title":"J. Med. Assoc. Thai."},{"key":"342_CR9","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1510\/icvts.2009.223024","volume":"10","author":"A Corno","year":"2010","unstructured":"Corno, A., C. Vergara, C. Subramanian, R. Johnson, T. Passerini, A. Veneziani, L. Formaggia, N. Alphonso, A. Quarteroni, and J. Jarvis. Assisted Fontan procedure: animal and in vitro models and computational fluid dynamics study. Interact. Cardio Vasc. Thorac. Surg. 10:679\u2013684, 2010.","journal-title":"Interact. Cardio Vasc. Thorac. Surg."},{"key":"342_CR10","doi-asserted-by":"publisher","first-page":"502","DOI":"10.1016\/S0022-5223(96)70302-1","volume":"111","author":"M Leval de","year":"1996","unstructured":"de Leval, M., G. Dubini, F. Migliavacca, H. Jalali, G. Camporini, A. Redington, and R. Pietrabissa. Use of computational fluid dynamics in the design of surgical procedures: application to the study of competitive flows in cavopulmonary connections. J. Thorac. Cardiovasc. Surg. 111:502\u2013513, 1996.","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"342_CR11","doi-asserted-by":"publisher","first-page":"408","DOI":"10.1016\/j.jbiomech.2012.10.045","volume":"46","author":"Y Delorme","year":"2013","unstructured":"Delorme, Y., K. Anupindi, A. Kerlo, D. Shetty, M. Rodefeld, J. Chen, and S. Frankel. Large eddy simulation of powered Fontan hemodynamics. J. Biomech. 46:408\u2013422, 2013.","journal-title":"J. Biomech."},{"key":"342_CR12","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1007\/s00466-011-0599-0","volume":"48","author":"M Esmaily-Moghadam","year":"2011","unstructured":"Esmaily-Moghadam, M., Y. Bazilevs, T. Hsia, I. Vignon-Clementel, and A. Mardsen. A comparison of outlet boundary treatments for prevention of backflow divergence with relevance to blood flow simulations. Comput. Mech. 48:277\u2013291, 2011.","journal-title":"Comput. Mech."},{"key":"342_CR13","doi-asserted-by":"publisher","first-page":"1141","DOI":"10.1007\/s00466-013-0868-1","volume":"52","author":"M Esmaily-Moghadam","year":"2013","unstructured":"Esmaily-Moghadam, M., Y. Bazilevs, and A. Mardsen. A new preconditioning technique for implicitly coupled multidomain simulations with applications to hemodynamics. Comput. Mech. 52:1141\u20131152, 2013.","journal-title":"Comput. Mech."},{"key":"342_CR14","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1016\/j.jtcvs.2014.10.035","volume":"149","author":"M Esmaily-Moghadam","year":"2015","unstructured":"Esmaily-Moghadam, M., T. Hsia, and A. Mardsen. The assisted bidirectional Glenn: A novel surgical approach for first-stage single-ventricle heart palliation. J. Thorac. Cardiovasc. Surg. 149:699\u2013705, 2015.","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"342_CR15","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1136\/thx.26.3.240","volume":"26","author":"F Fontan","year":"1971","unstructured":"Fontan, F., and E. Baudet. Surgical repair of tricuspid atresia. Thorax 26:240\u2013248, 1971.","journal-title":"Thorax"},{"key":"342_CR16","doi-asserted-by":"publisher","first-page":"1145","DOI":"10.1152\/japplphysiol.00372.2016","volume":"121","author":"K Forton","year":"2016","unstructured":"Forton, K., Y. Motohi, G. Deboeck, V. Faoro, and R. Naeije. Effects of body position on exercise capacity and pulmonary vascular pressure-flow relationships. J. Appl. Physiol. 121:1145\u20131150, 2016.","journal-title":"J. Appl. Physiol."},{"key":"342_CR17","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1016\/S0735-1097(97)00206-4","volume":"30","author":"M Geleijnse","year":"1997","unstructured":"Geleijnse, M., P. Fioretti, and J. Roelandt. Methodology, feasibility, safety and diagnostic accuracy of dobutamine stress echocardiography. J. Am. Coll. Cardiol. 30:595\u2013606, 1997.","journal-title":"J. Am. Coll. Cardiol."},{"key":"342_CR18","doi-asserted-by":"publisher","first-page":"839","DOI":"10.1136\/hrt.2004.051789","volume":"91","author":"M Gewillig","year":"2005","unstructured":"Gewillig, M. Congenital heart disease the Fontan circulation. Heart 91:839\u2013846, 2005.","journal-title":"Heart"},{"key":"342_CR19","doi-asserted-by":"publisher","first-page":"1081","DOI":"10.1136\/heartjnl-2015-307467","volume":"102","author":"M Gewillig","year":"2016","unstructured":"Gewillig, M., and S. Brown. The Fontan circulation after 45\u00a0years: update in physiology. Heart 102:1081\u20131086, 2016.","journal-title":"Heart"},{"key":"342_CR20","doi-asserted-by":"publisher","first-page":"428","DOI":"10.1510\/icvts.2009.218594","volume":"10","author":"M Gewillig","year":"2010","unstructured":"Gewillig, M., S. Brown, B. Eyskens, R. Heying, J. Ganame, W. Budts, A. Gerche, and M. Gorenflo. State-of-the-art congential the Fontan circulation: who controls the cardiac output? Interact. Cardio Vasc. Thorac. Surg. 10:428\u2013433, 2010.","journal-title":"Interact. Cardio Vasc. Thorac. Surg."},{"key":"342_CR21","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/j.hfc.2013.09.010","volume":"10","author":"M Gewillig","year":"2014","unstructured":"Gewillig, M., and D. Goldberg. Failure of the Fontan circulation. Heart Failure Clin. 10:105\u2013116, 2014.","journal-title":"Heart Failure Clin."},{"key":"342_CR22","doi-asserted-by":"publisher","first-page":"1169","DOI":"10.1016\/j.amjcard.2009.12.020","volume":"105","author":"B Goldstein","year":"2010","unstructured":"Goldstein, B., C. Connor, L. Gooding, and A. Rocchini. Relation of systemic venous return, pulmonary vascular resistance, and diastolic dysfunction to exercise capacity in patients with single ventricle receiving Fontan palliation. Am. J. Cardiol. 105:1169\u20131175, 2010.","journal-title":"Am. J. Cardiol."},{"key":"342_CR23","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1161\/01.RES.17.4.340","volume":"17","author":"J Greenfield","year":"1965","unstructured":"Greenfield, J., and D. Fry. Relationship between instantaneous aortic flow and the pressure gradient. Circ. Res. 17:340\u2013348, 1965.","journal-title":"Circ. Res."},{"key":"342_CR24","doi-asserted-by":"publisher","first-page":"522","DOI":"10.1016\/j.jtcvs.2012.11.031","volume":"146","author":"R Henaine","year":"2013","unstructured":"Henaine, R., M. Vergnat, E. Bacha, B. Baudet, V. Lambert, E. Belli, and A. Serraf. Effects of lack of pulsatility on pulmonary endothelial function in the Fontan circulation. J. Thorac. Cardiovasc. Surg. 146:522\u2013529, 2013.","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"342_CR25","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1161\/01.CIR.86.1.196","volume":"86","author":"Z Hijazi","year":"1992","unstructured":"Hijazi, Z., J. Fahey, C. Kleinman, G. Kopf, and W. Hellenbrand. Hemodyanmic evaluation before and after closure of fenestrated Fontan: an acute study of changes in oxygen delivery. Circulation 86:196\u2013202, 1992.","journal-title":"Circulation"},{"key":"342_CR26","doi-asserted-by":"publisher","first-page":"1227","DOI":"10.1161\/01.CIR.0000087406.27922.6B","volume":"108","author":"V Hjortdal","year":"2003","unstructured":"Hjortdal, V., K. Emmertson, E. Stenbog, T. Frund, M. Schmidt, O. Kromann, K. Sorensen, and E. Pedersen. Effects of exercise and respriation on blood flow in total cavopulmonary connection: a real-time magnetic resonance flow study. Circulation 108:1227\u20131231, 2003.","journal-title":"Circulation"},{"key":"342_CR27","doi-asserted-by":"publisher","first-page":"S204","DOI":"10.1161\/CIRCULATIONAHA.110.010769","volume":"124","author":"T Hsia","year":"2011","unstructured":"Hsia, T., D. Cosentino, C. Corsini, G. Pennati, G. Dubini, and F. Migliavacca. Use of mathematical modeling to compare and predict hemodynamic effects between hybrid and surgical Norwood palliations for hypoplastic left heart syndrome. Circulation 124:S204\u2013S210, 2011.","journal-title":"Circulation"},{"key":"342_CR28","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1016\/j.jss.2003.08.004","volume":"116","author":"T Hsia","year":"2004","unstructured":"Hsia, T., F. Migliavacca, S. Pittaccio, A. Radaelli, G. Dubini, G. Pennati, and M. de Leval. Computational fluid dynamic study of flow optimization in realistic models of the total cavopulmonary connections. J. Surg. Res. 116:305\u2013313, 2004.","journal-title":"J. Surg. Res."},{"key":"342_CR29","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1016\/j.jtcvs.2011.08.013","volume":"144","author":"K Itatani","year":"2012","unstructured":"Itatani, K., K. Miyaji, Y. Qian, J. Liu, T. Miyakoshi, A. Murakami, M. Ono, and M. Umeza. Influence of surgical arch reconstruction methods on single ventricle workload in the Norwood procedure. J. Thorac. Cardiovasc. Surg. 144:130\u2013138, 2012.","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"342_CR30","doi-asserted-by":"publisher","first-page":"565","DOI":"10.1016\/j.athoracsur.2009.04.109","volume":"88","author":"K Itatani","year":"2009","unstructured":"Itatani, K., K. Miyaji, T. Tomoyasu, Y. Nakahata, O. Kuniyoshi, S. Takamoto, and M. Ishii. Optimal conduit size of the extracardiac fontan operation based on energy loss and flow stagnation. Soc. Thorac. Surg. 88:565\u2013573, 2009.","journal-title":"Soc. Thorac. Surg."},{"key":"342_CR31","doi-asserted-by":"publisher","first-page":"6391","DOI":"10.1016\/j.ces.2005.04.055","volume":"60","author":"M Kandakure","year":"2005","unstructured":"Kandakure, M., V. Gaiker, and A. W. Patwardhan. Hydrodynamic aspects of ejectors. Chem. Eng. Sci. 60:6391\u20136402, 2005.","journal-title":"Chem. Eng. Sci."},{"issue":"5","key":"342_CR32","first-page":"1525","volume":"88","author":"M Kroll","year":"1996","unstructured":"Kroll, M., D. Hellums, L. McIntire, A. Schafer, and J. Moake. Platelets and shear stress. J. Am. Soc. Hematol. 88(5):1525\u20131541, 1996.","journal-title":"J. Am. Soc. Hematol."},{"key":"342_CR33","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1016\/j.jbiomech.2012.10.023","volume":"46","author":"E Kung","year":"2013","unstructured":"Kung, E., A. Baretta, C. Baker, G. Arbia, G. Biglino, C. Corsini, S. Schievano, I. Vignon-Clementel, G. Dubini, G. Pennati, A. Taylor, A. Dorfman, A. Hlavacek, A. Mardsen, T. Hsia, and F. Migliavacca. Predicitive modeling of the virtual Hemi-Fontan operation for second stage single ventricle palliation: Two patient-specific cases. J. Biomech. 46:423\u2013429, 2013.","journal-title":"J. Biomech."},{"key":"342_CR34","first-page":"081007-1","volume":"136","author":"E Kung","year":"2014","unstructured":"Kung, E., G. Pennati, F. Migliavacca, T. Hsia, R. Figliola, A. Mardsen, and A. Giardini. A simulation protocol for exercise physiology in Fontan patients using a closed loop lumped-parameter model. J. Biomech. Eng. 136:081007-1\u2013081007-14, 2014.","journal-title":"J. Biomech. Eng."},{"key":"342_CR35","doi-asserted-by":"publisher","first-page":"1129","DOI":"10.1016\/j.jbiomech.2004.05.027","volume":"38","author":"K Lagana","year":"2005","unstructured":"Lagana, K., R. Balossino, F. Migliavacca, G. Pennati, E. Bove, M. de Leval, and G. Dubini. Multiscale modeling of the cardiovascular system: application to the study of pulmonary and coronary perfusions in the univentricular circulation. J. Biomech. 38:1129\u20131141, 2005.","journal-title":"J. Biomech."},{"key":"342_CR36","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1002\/cnm.1485","volume":"28","author":"C Long","year":"2012","unstructured":"Long, C., M. Hsu, Y. Bazilevs, J. Feinstein, and A. Marsden. Fluid\u2013structure interaction simulations of the Fontan procedure using variable wall properties. Int. J. Numer. Meth. Biomed. Eng. 28:513\u2013527, 2012.","journal-title":"Int. J. Numer. Meth. Biomed. Eng."},{"key":"342_CR37","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1186\/1742-4682-8-14","volume":"8","author":"C Luo","year":"2011","unstructured":"Luo, C., D. Ramachandran, D. Ware, T. Ma, and J. Clark. Modeling left ventricular diastolic dysfunction: classification and key indicators. Theor. Biol. Med. Model. 8:14, 2011.","journal-title":"Theor. Biol. Med. Model."},{"key":"342_CR38","doi-asserted-by":"publisher","first-page":"394","DOI":"10.1016\/j.jtcvs.2008.06.043","volume":"137","author":"A Mardsen","year":"2009","unstructured":"Mardsen, A., A. Bernstein, V. Reddy, S. Shadden, R. Spilker, F. Chan, C. Taylor, and J. Feinstein. Evaluation of a novel Y-shaped extracardiac Fontan baffle using computational fluid dynamics. J. Thorac. Cardiovasc. Surg. 137:394\u2013403, 2009.","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"342_CR39","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1007\/s10439-006-9224-3","volume":"35","author":"A Mardsen","year":"2007","unstructured":"Mardsen, A., I. Vignon-Clementel, F. Chan, J. Feinstein, and C. Taylor. Effects of exercise and respiration on hemodynamic efficiency in CFD simulations of the total cavopulmonary connection. Ann. Biomed. Eng. 35:250\u2013263, 2007.","journal-title":"Ann. Biomed. Eng."},{"key":"342_CR40","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1161\/01.CIR.23.2.241","volume":"23","author":"H Marshall","year":"1961","unstructured":"Marshall, H., H. Swan, H. Burchell, and E. Wood. Effect of breathing oxygen on pulmonary artery pressure and pulmonary vascular resistance in patients with ventricular septal defect. Circulation 23:241\u2013252, 1961.","journal-title":"Circulation"},{"key":"342_CR41","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1109\/10.752936","volume":"46","author":"F Migliavacca","year":"1999","unstructured":"Migliavacca, F., P. Kilner, G. Pennati, G. Dubini, R. Pietrabissa, R. Fumero, and M. de Leval. Computational fluid dynamic and magnetic resonance analyses of flow distribution between the lungs after total cavopulmonary connection. IEEE Trans. Biomed. Eng. 46:393\u2013399, 1999.","journal-title":"IEEE Trans. Biomed. Eng."},{"key":"342_CR42","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1016\/j.jcp.2012.07.035","volume":"244","author":"M Moghadam","year":"2013","unstructured":"Moghadam, M., I. Vignon-Clementel, R. Figliola, and A. Mardsen. A modular numerical method for implicit 0D\/3D coupling in cardiovascular finite element simulations. J. Comput. Phys. 244:63\u201379, 2013.","journal-title":"J. Comput. Phys."},{"issue":"1","key":"342_CR43","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1002\/cphy.c100091","volume":"2","author":"R Naeije","year":"2012","unstructured":"Naeije, R., and N. Chesler. Pulmonary circulation at exercise. Compr. Physiol. 2(1):711\u2013741, 2012.","journal-title":"Compr. Physiol."},{"key":"342_CR44","unstructured":"Ni, M. Computational proof of concept and analysis of a self-powered Fontan circulation, University of Central Florida, PhD Dissertation, 2017"},{"key":"342_CR45","doi-asserted-by":"publisher","first-page":"1140","DOI":"10.1097\/01.CCM.0000060126.75746.32","volume":"31","author":"A Pagnamenta","year":"2003","unstructured":"Pagnamenta, A., P. Fesler, A. Vandinivit, S. Brimioulle, and R. Naeije. Pulmonary vascular effects of dobutamine in experimental pulmonary hypertension. Crit. Care Med. 31:1140\u20131146, 2003.","journal-title":"Crit. Care Med."},{"issue":"12","key":"342_CR46","doi-asserted-by":"publisher","first-page":"1008","DOI":"10.1002\/bdra.20735","volume":"88","author":"SE Parker","year":"2010","unstructured":"Parker, S. E., C. T. Mai, M. A. Canfield, R. Rickard, Y. Wang, R. E. Meyer, P. Anderson, C. A. Mason, J. S. Collins, R. S. Kirby, and A. Correa. Updated national birth prevalence estimates for selected birth defects in the United States, 2004\u20132006. Birth Defects Res. A Clin. Mol. Teratol. 88(12):1008\u20131016, 2010.","journal-title":"Birth Defects Res. A Clin. Mol. Teratol."},{"key":"342_CR47","doi-asserted-by":"publisher","first-page":"618","DOI":"10.1097\/01.mat.0000176169.73987.0d","volume":"51","author":"K Pekkan","year":"2005","unstructured":"Pekkan, K., D. Frakes, D. Zelicourt, C. Lucas, J. Parks, and A. Yoganathan. Coupling pediatric ventricle assist devices to the Fontan circulation: simulations with a lumped-parameter model. ASAIO J. 51:618\u2013628, 2005.","journal-title":"ASAIO J."},{"key":"342_CR48","doi-asserted-by":"publisher","first-page":"1005","DOI":"10.1016\/S0003-4975(02)04372-2","volume":"75","author":"J Petrofski","year":"2003","unstructured":"Petrofski, J., C. Hoopes, T. Bashmore, S. Russel, and C. Milano. Mechanical ventricular support lowers pulmonary vascular resistance in a patient with congenital heart disease. Ann. Thorac. Surg. 75:1005\u20131007, 2003.","journal-title":"Ann. Thorac. Surg."},{"key":"342_CR49","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1007\/s007910100063","volume":"4","author":"A Quarteroni","year":"2001","unstructured":"Quarteroni, A., S. Ragni, and A. Veneziani. Coupling between lumped and distributed models for blood flow problems. Comput. Vis. Sci. 4:111\u2013124, 2001.","journal-title":"Comput. Vis. Sci."},{"key":"342_CR50","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1137\/S1540345902408482","volume":"1","author":"A Quarteroni","year":"2003","unstructured":"Quarteroni, A., and A. Veneziani. Analysis of a geometrical multiscale model based on the coupling of ODEs and PDEs for blood flow simulations. Multiscale Model. Simul. 1:173\u2013195, 2003.","journal-title":"Multiscale Model. Simul."},{"key":"342_CR51","doi-asserted-by":"publisher","first-page":"L419","DOI":"10.1152\/ajplung.00162.2004","volume":"288","author":"J Reeves","year":"2005","unstructured":"Reeves, J., J. Linehan, and K. Stenmark. Distensibility of the normal human lung circulation during exercise. Am. J. Physiol. Lung Cell. Mol. Physiol. 288:L419\u2013L425, 2005.","journal-title":"Am. J. Physiol. Lung Cell. Mol. Physiol."},{"key":"342_CR52","doi-asserted-by":"publisher","first-page":"952","DOI":"10.1111\/echo.12163","volume":"30","author":"I Rivera","year":"2013","unstructured":"Rivera, I., M. Mendonca, J. Andrade, V. Moises, O. Campos, C. Silva, and A. Carvalho. Pulmonary venous flow index as a predictor of pulmonary vascular resistance variability in congenital heart disease with increased pulmonary flow: a comparative study before and after oxygen inhalation. Echocardiography. 30:952\u2013960, 2013.","journal-title":"Echocardiography."},{"key":"342_CR53","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1053\/j.pcsu.2011.01.015","volume":"14","author":"M Rodefeld","year":"2011","unstructured":"Rodefeld, M., S. Frankel, and G. Giridharan. Cavopulmonary assist: (Em)powering the univentricular Fontan circulation. Semin. Thorac. Cardiovasc. Surg. Pediatri. Card Surg. Annu. 14:45\u201354, 2011.","journal-title":"Semin. Thorac. Cardiovasc. Surg. Pediatri. Card Surg. Annu."},{"key":"342_CR54","doi-asserted-by":"publisher","first-page":"2228","DOI":"10.1007\/s10439-012-0579-3","volume":"40","author":"S Sankaran","year":"2012","unstructured":"Sankaran, S., M. Moghadam, A. Kahn, E. Tseng, J. Guccione, and A. Mardsen. Patient-specific multiscale modeling of blood flow for coronary artery bypass graft surgery. Ann. Biomed. Eng. 40:2228\u20132242, 2012.","journal-title":"Ann. Biomed. Eng."},{"key":"342_CR55","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1016\/j.jtcvs.2014.12.040","volume":"149","author":"D Schiavazzi","year":"2015","unstructured":"Schiavazzi, D., E. Kung, A. Mardsen, C. Baker, G. Pennati, T. Hsia, A. Hlavacek, and A. Dorfman. Hemodynamic effects of left pulmonary artery stenosis after superior cavopulmonary connection: a patient-specific multiscale modeling study. J. Thorac. Cardiovasc. Surg. 149:689\u2013696, 2015.","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"342_CR56","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1161\/CIRCIMAGING.109.931592","volume":"3","author":"B Schmitt","year":"2010","unstructured":"Schmitt, B., P. Steendijk, S. Ovroutski, K. Lunze, P. Rahmanzadeh, N. Maarouf, P. Ewert, F. Berger, and T. Kuehne. Pulmonary vascular resistance, collateral flow, and ventricular function in patients with a Fontan circulation at rest and during Dobutamine stress. Circ. Cardiovasc. Imaging 3:623\u2013631, 2010.","journal-title":"Circ. Cardiovasc. Imaging"},{"key":"342_CR57","doi-asserted-by":"publisher","first-page":"1043","DOI":"10.1161\/01.CIR.65.6.1043","volume":"65","author":"G Shachar","year":"1982","unstructured":"Shachar, G., B. Fuhrman, Y. Wang, R. Lucas, and J. Lock. Rest and exercise hemodynamics after the Fontan procedure. Circulation 65:1043\u20131048, 1982.","journal-title":"Circulation"},{"key":"342_CR58","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1007\/s12576-015-0422-3","volume":"66","author":"S Shimizu","year":"2016","unstructured":"Shimizu, S., T. Kawada, D. Une, M. Fukumitsu, M. Turner, A. Kamiya, T. Shishido, and M. Sugimachi. Partial cavopulmonary assist from the inferior vena cava to the pulmonary artery improves hemodynamics in failing Fontan circulation: a theoretical analysis. J. Physiol. Sci. 66:249\u2013255, 2016.","journal-title":"J. Physiol. Sci."},{"key":"342_CR59","doi-asserted-by":"publisher","first-page":"470","DOI":"10.4103\/2045-8932.105035","volume":"2","author":"B Tang","year":"2012","unstructured":"Tang, B., S. Pickard, F. Chan, P. Tsao, C. Taylor, and J. Feinstein. Wall shear stress is decreased in the pulmonary arteries of patients with pulmonary arterial hypertension: An image-based, computational fluid dynamics study. Pulm. Circ. 2:470\u2013476, 2012.","journal-title":"Pulm. Circ."},{"issue":"3","key":"342_CR60","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1111\/aor.12152","volume":"38","author":"J Valdovinos","year":"2014","unstructured":"Valdovinos, J., E. Shkolyar, G. Carman, and D. Levi. In vitro evaluation of an external compression device for Fontan mechanical assistance. Artif. Organs 38(3):199\u2013207, 2014.","journal-title":"Artif. Organs"},{"key":"342_CR61","doi-asserted-by":"publisher","first-page":"3886","DOI":"10.1016\/j.ces.2008.04.012","volume":"63","author":"R Yadav","year":"2008","unstructured":"Yadav, R., and A. Patwardhan. Design aspects of ejectors: effects of suction chamber geometry. Chem. Eng. Sci. 63:3886\u20133897, 2008.","journal-title":"Chem. Eng. Sci."}],"container-title":["Cardiovascular Engineering and Technology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s13239-018-0342-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s13239-018-0342-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s13239-018-0342-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,14]],"date-time":"2022-08-14T16:08:00Z","timestamp":1660493280000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s13239-018-0342-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2,20]]},"references-count":61,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,6]]}},"alternative-id":["342"],"URL":"https:\/\/doi.org\/10.1007\/s13239-018-0342-5","relation":{},"ISSN":["1869-408X","1869-4098"],"issn-type":[{"type":"print","value":"1869-408X"},{"type":"electronic","value":"1869-4098"}],"subject":[],"published":{"date-parts":[[2018,2,20]]},"assertion":[{"value":"10 October 2017","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 February 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 February 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This study was funded by an Innovative Grant award from the American Heart Association (AHA 5IRG22470015).","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Funding"}},{"value":"Marcus Ni declares that he has no conflict of interest. Ray Prather declares that he has no conflict of interest. Giovanna Rodriguez declares that she has no conflict of interest. Rachel Quinn declares that she has no conflict of interest. Eduardo Divo declares that he has no conflict of interest. Mark Fogel declares that he has no conflict of interest. Alain Kassab declares that he has no conflict of interest. William DeCampli declares that he has no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This study does not contain any studies with human participants or animals performed by the authors.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}