{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T14:45:02Z","timestamp":1792421102031,"version":"4.5.0"},"reference-count":67,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100001809","name":"the National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["grant number 81771927"],"award-info":[{"award-number":["grant number 81771927"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"the National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81601462"],"award-info":[{"award-number":["81601462"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cardiovasc Eng Tech"],"published-print":{"date-parts":[[2021,6]]},"DOI":"10.1007\/s13239-021-00527-w","type":"journal-article","created":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T18:02:55Z","timestamp":1614621775000},"page":"361-372","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":78,"title":["Left Atrial Remodeling Mechanisms Associated with Atrial Fibrillation"],"prefix":"10.1007","volume":"12","author":[{"given":"Defu","family":"Qiu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liqing","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dhanjoo N.","family":"Ghista","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8600-1105","authenticated-orcid":false,"given":"Kelvin K. L.","family":"Wong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,3,1]]},"reference":[{"issue":"1","key":"527_CR1","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1111\/j.1540-8167.2010.01876.x","volume":"22","author":"N Akoum","year":"2011","unstructured":"Akoum, N., M. Daccarett, C. McGann, et al. Atrial fibrosis helps select the appropriate patient and strategy in catheter ablation of atrial fibrillation: a DE-MRI guided approach. J. Cardiovasc. Electrophysiol. 22(1):16\u201322, 2011.","journal-title":"J. Cardiovasc. Electrophysiol."},{"key":"527_CR2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmpb.2019.105163","author":"B Arindam","year":"2019","unstructured":"Arindam, B., A. Adel, C. Himadri, et al. Three dimensional numerical analysis of hemodynamic of stenosed artery considering realistic outlet boundary conditions. Comput. Methods Programs Biomed. 2019. https:\/\/doi.org\/10.1016\/j.cmpb.2019.105163.","journal-title":"Comput. Methods Programs Biomed."},{"issue":"3","key":"527_CR3","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1097\/CRD.0b013e318274956d","volume":"21","author":"PS Azevedo","year":"2013","unstructured":"Azevedo, P. S., M. F. Minicucci, P. P. Santos, et al. Energy metabolism in cardiac remodeling and heart failure. Cardiol. Rev. 21(3):135\u2013140, 2013.","journal-title":"Cardiol. Rev."},{"issue":"3","key":"527_CR4","first-page":"327","volume":"2","author":"AS Barth","year":"2009","unstructured":"Barth, A. S., and G. F. Tomaselli. Cardiac metabolism and arrhythmias. Circulation 2(3):327\u2013335, 2009.","journal-title":"Circulation"},{"issue":"4","key":"527_CR5","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1097\/FJC.0b013e3182116e39","volume":"57","author":"J Baum","year":"2011","unstructured":"Baum, J., and H. S. Duffy. Fibroblasts and myofibroblasts: what are we talking about? J. Cardiovasc. Pharmacol. 57(4):376\u2013379, 2011.","journal-title":"J. Cardiovasc. Pharmacol."},{"issue":"1","key":"527_CR6","first-page":"23","volume":"125","author":"LV Boersma","year":"2012","unstructured":"Boersma, L. V., M. Castella, B. W. Van, et al. Atrial fibrillation catheter ablation versus surgical ablation treatment (FAST) a 2-center randomized clinical trial. South China J. Cardiol. 125(1):23, 2012.","journal-title":"South China J. Cardiol."},{"issue":"4","key":"527_CR7","first-page":"H1313","volume":"284","author":"YM Cha","year":"2003","unstructured":"Cha, Y. M., P. P. Dzeja, W. K. Shen, et al. Failing atrial myocardium: energetic deficits accompany structural remodeling and electrical instability. Am. J. Physiol. 284(4):H1313\u2013H1320, 2003.","journal-title":"Am. J. Physiol."},{"key":"527_CR8","doi-asserted-by":"crossref","first-page":"2744","DOI":"10.1161\/CIRCULATIONAHA.105.590018","volume":"113","author":"C Cheng","year":"2006","unstructured":"Cheng, C., D. Tempel, R. van Haperen, et al. Atherosclerotic lesion size and vulnerability are determined by patterns of fluid shear stress. Circulation 113:2744\u20132753, 2006.","journal-title":"Circulation"},{"issue":"5","key":"527_CR9","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1007\/s10557-007-6053-z","volume":"21","author":"SI Chrysostomakis","year":"2007","unstructured":"Chrysostomakis, S. I., I. K. Karalis, E. N. Simantirakis, et al. Angiotensin II type 1 receptor inhibition is associated with reduced tachyarrhythmia-induced ventricular interstitial fibrosis in a goat atrial fibrillation model. Cardiovasc. Drugs Ther. 21(5):357\u2013365, 2007.","journal-title":"Cardiovasc. Drugs Ther."},{"key":"527_CR10","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1161\/CIRCRESAHA.110.233841","volume":"108","author":"S Cuhlmann","year":"2011","unstructured":"Cuhlmann, S., K. Van der Heiden, D. Saliba, et al. Disturbed Blood Flow Induces RelA Expression via c-Jun N-Terminal Kinase 1: A Novel Mode of NF- kB Regulation That Promotes Arterial Inflammation. Circ. Res. 108:950\u2013959, 2011.","journal-title":"Circ. Res."},{"issue":"5","key":"527_CR11","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1536\/ihj.15-098","volume":"56","author":"Z Da","year":"2015","unstructured":"Da, Z., W. Zhong, R. J. Van der Geest, et al. Accuracy of late gadolinium enhancement - magnetic resonance imaging in the measurement of left atrial substrate remodeling in patients with rheumatic mitral valve disease and persistent atrial fibrillation. Int. Heart J. 56(5):505\u2013510, 2015.","journal-title":"Int. Heart J."},{"issue":"14","key":"527_CR12","doi-asserted-by":"crossref","first-page":"1466","DOI":"10.1161\/CIRCULATIONAHA.112.001207","volume":"127","author":"K Dawson","year":"2013","unstructured":"Dawson, K., R. Wakili, B. Ordog, et al. MicroRNA29: a mechanistic contributor and potential biomarker in atrial fibrillation. Circulation 127(14):1466\u20131475, 2013.","journal-title":"Circulation"},{"key":"527_CR13","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1093\/cvr\/cvr077","volume":"90","author":"T Doenst","year":"2011","unstructured":"Doenst, T., and E. D. Abel. Spotlight on metabolic remodeling is heart failure. Cardiovasc. Res. 90:191\u2013193, 2011.","journal-title":"Cardiovasc. Res."},{"issue":"3","key":"527_CR14","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1093\/cvr\/cvp414","volume":"86","author":"T Doenst","year":"2010","unstructured":"Doenst, T., G. Pytel, A. Schrepper, et al. Decreased rates of substrate oxidation ex vivo predict the onset of heart failure and contractile dysfunction in rats with pressure overload. Cardiovasc. Res. 86(3):461\u2013470, 2010.","journal-title":"Cardiovasc. Res."},{"issue":"1","key":"527_CR15","first-page":"64","volume":"6","author":"P Dyverfeldt","year":"2013","unstructured":"Dyverfeldt, P., M. D. Hope, E. E. Tseng, et al. Magnetic resonance measurement of turbulent kinetic energy for the estimation of irreversible pressure loss in aortic stenosis. JACC 6(1):64\u201371, 2013.","journal-title":"JACC"},{"key":"527_CR16","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/1532-429X-14-16","volume":"14","author":"CJ Fran\u00e7ois","year":"2012","unstructured":"Fran\u00e7ois, C. J., S. Srinivasan, M. L. Schiebler, et al. 4D cardiovascular magnetic resonance velocity mapping of alterations of right heart flow patterns and main pulmonary artery hemodynamics in tetralogy of Fallot. J. Cardiovasc. Magn. Reson. 14:16, 2012.","journal-title":"J. Cardiovasc. Magn. Reson."},{"issue":"2","key":"527_CR17","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1111\/echo.12003","volume":"30","author":"T Fuchs","year":"2013","unstructured":"Fuchs, T., E. L. Baron, M. Leitman, et al. Does chronic atrial fibrillation induce cardiac remodeling? Echocardiography 30(2):140\u2013146, 2013.","journal-title":"Echocardiography"},{"key":"527_CR18","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1136\/heart.86.4.448","volume":"86","author":"A Fyrenius","year":"2001","unstructured":"Fyrenius, A., L. Wigstr\u00f6m, T. Ebbers, et al. Three dimensional flow in the human left atrium. Heart 86:448\u2013455, 2001.","journal-title":"Heart"},{"issue":"2","key":"527_CR19","first-page":"H497","volume":"298","author":"JD Gardner","year":"2010","unstructured":"Gardner, J. D., D. B. Murray, T. G. Voloshenyuk, et al. Estrogen attenuates chronic volume overload induced structural and functional remodeling in male rat hearts. AJP 298(2):H497\u2013H504, 2010.","journal-title":"AJP"},{"issue":"10","key":"527_CR20","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1016\/j.cjca.2013.07.679","volume":"29","author":"FT Han","year":"2013","unstructured":"Han, F. T., N. Akoum, and N. Marrouche. Value of magnetic resonance imaging in guiding atrial fibrillation management. Can. J. Cardiol. 29(10):1194\u20131202, 2013.","journal-title":"Can. J. Cardiol."},{"issue":"6","key":"527_CR21","doi-asserted-by":"crossref","first-page":"673","DOI":"10.2217\/fca.15.65","volume":"11","author":"FT Han","year":"2015","unstructured":"Han, F. T., and N. Marrouche. An atrial fibrosis-based approach for atrial fibrillation ablation. Future Cardiol. 11(6):673\u2013681, 2015.","journal-title":"Future Cardiol."},{"issue":"9","key":"527_CR22","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.1161\/CIRCRESAHA.114.302226","volume":"114","author":"J Heijman","year":"2014","unstructured":"Heijman, J., N. Voigt, S. Nattel, et al. Cellular and molecular electrophysiology of atrial fibrillation initiation, maintenance, and progression. Circ. Res. 114(9):1483\u20131499, 2014.","journal-title":"Circ. Res."},{"issue":"6","key":"527_CR23","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/j.jacc.2013.10.055","volume":"63","author":"BD Hoit","year":"2014","unstructured":"Hoit, B. D. Left atrial size and function: role in prognosis. J. Am. Coll. Cardiol. 63(6):493\u2013505, 2014.","journal-title":"J. Am. Coll. Cardiol."},{"issue":"1","key":"527_CR24","doi-asserted-by":"crossref","first-page":"0","DOI":"10.1016\/j.ijcard.2009.05.065","volume":"146","author":"HJ Hwang","year":"2011","unstructured":"Hwang, H. J., J. W. Ha, B. Joung, et al. Relation of inflammation and left atrial remodeling in atrial fibrillation occurring in early phase of acute myocardial infarction. Int. J. Cardiol. 146(1):0\u201331, 2011.","journal-title":"Int. J. Cardiol."},{"issue":"20","key":"527_CR25","doi-asserted-by":"crossref","first-page":"2264","DOI":"10.1161\/CIRCULATIONAHA.111.019893","volume":"124","author":"YK Iwasaki","year":"2011","unstructured":"Iwasaki, Y. K., K. Nishida, T. Kato, et al. Atrial fibrillation pathophysiology implications for management. Circulation 124(20):2264\u20132274, 2011.","journal-title":"Circulation"},{"issue":"58","key":"527_CR26","doi-asserted-by":"crossref","first-page":"101868","DOI":"10.1016\/j.bspc.2020.101868","volume":"1","author":"M Jalali","year":"2020","unstructured":"Jalali, M., H. Behnam, F. Davoodi, and M. Shojaeifard. Temporal super-resolution of 2D\/3D echocardiography using cubic B-spline interpolation. Biomed. Signal Process. Control 1(58):101868, 2020.","journal-title":"Biomed. Signal Process. Control"},{"issue":"6","key":"527_CR27","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/j.tcm.2014.12.015","volume":"25","author":"J Jalife","year":"2015","unstructured":"Jalife, J., and K. Kaur. Atrial remodeling, fibrosis, and atrial fibrillation. Trends Cardiovasc. Med. 25(6):475\u2013484, 2015.","journal-title":"Trends Cardiovasc. Med."},{"issue":"10","key":"527_CR28","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1161\/01.CIR.101.10.1185","volume":"101","author":"JV Jayachandran","year":"2000","unstructured":"Jayachandran, J. V., H. J. Sih, W. Winkle, et al. Atrial fibrillation produced by prolonged rapid atrial pacing is associated with heterogeneous changes in atrial sympathetic innervation. Circulation 101(10):1185\u20131191, 2000.","journal-title":"Circulation"},{"issue":"1","key":"527_CR29","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.jacc.2003.07.030","volume":"43","author":"A Khan","year":"2004","unstructured":"Khan, A., G. W. Moe, N. Nili, et al. The cardiac atria are chambers of active remodeling and dynamic collagen turnover during evolving heart failure. J. Am. Coll. Cardiol. 43(1):68\u201376, 2004.","journal-title":"J. Am. Coll. Cardiol."},{"issue":"1","key":"527_CR30","doi-asserted-by":"crossref","first-page":"7871","DOI":"10.1038\/s41598-018-26212-y","volume":"8","author":"YG Kim","year":"2018","unstructured":"Kim, Y. G., J. Shim, S. K. Oh, et al. Different responses of left atrium and left atrial appendage to radiofrequency catheter ablation of atrial fibrillation: a follow up MRI study. Sci. Rep. 8(1):7871, 2018.","journal-title":"Sci. Rep."},{"issue":"6","key":"527_CR31","doi-asserted-by":"crossref","first-page":"3027","DOI":"10.1007\/s00330-018-5793-4","volume":"29","author":"C Klein","year":"2018","unstructured":"Klein, C., J. Brunereau, D. Lacroix, et al. Left atrial epicardial adipose tissue radiodensity is associated with electrophysiological properties of atrial myocardium in patients with atrial fibrillation. Eur. Radiol. 29(6):3027\u20133035, 2018.","journal-title":"Eur. Radiol."},{"key":"527_CR32","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1016\/j.media.2012.04.003","volume":"16","author":"SB Krittian","year":"2012","unstructured":"Krittian, S. B., P. Lamata, C. Michler, et al. A finite-element approach to the direct computation of relative cardiovascular pressure from time-resolved MR velocity data. Med. Image Anal. 16:1029\u20131037, 2012.","journal-title":"Med. Image Anal."},{"issue":"1","key":"527_CR33","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1186\/s12872-018-0776-6","volume":"18","author":"J Lacalzada-Almeida","year":"2018","unstructured":"Lacalzada-Almeida, J., M. M. Izquierdo-G\u00f3mez, C. Belleyo-Belkasem, et al. Interatrial block, and atrial remodeling assessed using speckle tracking echocardiography. BMC Cardiovas. Disord. 18(1):38, 2018.","journal-title":"BMC Cardiovas. Disord."},{"issue":"s1","key":"527_CR34","first-page":"s36","volume":"23","author":"CP Lau","year":"2012","unstructured":"Lau, C. P., H. F. Tse, C. W. Siu, et al. Atrial electrical and structural remodeling: implications for racial differences in atrial fibrillation. J. Cardiovasc. Electrophysiol. 23(s1):s36\u2013s40, 2012.","journal-title":"J. Cardiovasc. Electrophysiol."},{"issue":"6","key":"527_CR35","doi-asserted-by":"crossref","first-page":"0-1064","DOI":"10.1016\/j.ahj.2008.07.021","volume":"156","author":"DY Leung","year":"2008","unstructured":"Leung, D. Y., A. Boyd, A. A. Ng, et al. Echocardiographic evaluation of left atrial size and function: current understanding, pathophysiologic correlates, and prognostic implications. Am. Heart J. 156(6):0-1064, 2008.","journal-title":"Am. Heart J."},{"issue":"7","key":"527_CR36","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1007\/s10554-016-0876-2","volume":"32","author":"Y Li","year":"2016","unstructured":"Li, Y., Y. B. Deng, X. J. Bi, Y. N. Liu, J. Zhang, and L. Li. Evaluation of myocardial strain and artery elasticity using speckle tracking echocardiography and high-resolution ultrasound in patients with bicuspid aortic valve. Int. J. Cardiovasc. Imaging 32(7):1063\u20131069, 2016.","journal-title":"Int. J. Cardiovasc. Imaging"},{"issue":"2","key":"527_CR37","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/S0008-6363(00)00003-1","volume":"46","author":"YY Li","year":"2000","unstructured":"Li, Y. Y., C. F. McTiernan, and A. M. Feldman. Interplay of matrix metalloproteinases, tissue inhibitors of metalloproteinases and their regulators in cardiac matrix remodeling. Cardiovasc. Res. 46(2):214\u2013224, 2000.","journal-title":"Cardiovasc. Res."},{"key":"527_CR38","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1097\/00004728-200407000-00005","volume":"28","author":"M Markl","year":"2004","unstructured":"Markl, M., M. T. Draney, M. D. Hope, et al. Time-resolved 3-dimensional velocity mapping in the thoracic aorta: visualization of 3-directional blood flow patterns in healthy volunteers and patients. J. Comput. Assist. Tomogr. 28:459\u2013468, 2004.","journal-title":"J. Comput. Assist. Tomogr."},{"issue":"5","key":"527_CR39","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1001\/jama.2014.3","volume":"311","author":"NF Marrouche","year":"2014","unstructured":"Marrouche, N. F., D. Wilber, G. Hindricks, et al. Association of atrial tissue fibrosis identified by delayed enhancement MRI and atrial fibrillation catheter ablation: the DECAAF study. JAMA 311(5):498\u2013506, 2014.","journal-title":"JAMA"},{"issue":"9","key":"527_CR40","first-page":"918","volume":"13","author":"HMD Masamichi","year":"2010","unstructured":"Masamichi, H. M. D., D. C. M. D. Mark, and R. L. P. D. Kenneth. Cellular mechanisms of vagally mediated atrial tachyarrhythmia in isolated arterially perfused canine right atria. J. Cardiovasc. Electrophysiol. 13(9):918\u2013926, 2010.","journal-title":"J. Cardiovasc. Electrophysiol."},{"issue":"default","key":"527_CR41","first-page":"99","volume":"6","author":"JL Mclarty","year":"2013","unstructured":"Mclarty, J. L., J. Li, S. P. Levick, et al. Estrogen modulates the influence of cardiac inflammatory cells on function of cardiac fibroblasts. J. Inflamm. Res. 6(default):99\u2013108, 2013.","journal-title":"J. Inflamm. Res."},{"key":"527_CR42","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1111\/j.1540-8167.1999.tb00214.x","volume":"10","author":"S Nattle","year":"1999","unstructured":"Nattle, S. Electrophysiologic remodeling: are ion channels static players or dynamic movers? J. Cardiovasc. Electrophysiol. 10:1553\u20131556, 1999.","journal-title":"J. Cardiovasc. Electrophysiol."},{"issue":"3","key":"527_CR43","first-page":"388","volume":"4","author":"J Ng","year":"2011","unstructured":"Ng, J., R. Villuendas, I. Cokic, et al. Autonomic remodeling in the left atrium and pulmonary veins in heart failure: creation of a dynamic substrate for atrial fibrillation. Circulation 4(3):388\u2013396, 2011.","journal-title":"Circulation"},{"key":"527_CR44","doi-asserted-by":"crossref","unstructured":"Okumura Y. Inflammatory biomarkers in atrial fibrillation: are they linked to future outcomes? Heart, 2016.","DOI":"10.1136\/heartjnl-2015-309079"},{"issue":"2","key":"527_CR45","first-page":"e005047","volume":"10","author":"W Oliver","year":"2017","unstructured":"Oliver, W., G. Matthews, C. R. Ayers, et al. Factors associated with left atrial remodeling in the general populationCLINICAL PERSPECTIVE. Circulation 10(2):e005047, 2017.","journal-title":"Circulation"},{"issue":"21","key":"527_CR46","doi-asserted-by":"crossref","first-page":"2225","DOI":"10.1016\/j.jacc.2011.05.061","volume":"58","author":"PG Platonov","year":"2011","unstructured":"Platonov, P. G., L. B. Mitrofanova, V. Orshanskaya, et al. Structural abnormalities in atrial walls are associated with presence and persistency of atrial fibrillation but not with age. J. Am. Coll. Cardiol. 58(21):2225\u20132232.9, 2011.","journal-title":"J. Am. Coll. Cardiol."},{"key":"527_CR47","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/451042","author":"A Roberta","year":"2014","unstructured":"Roberta, A., C. P. Salvatore, C. Pio, et al. Left atrium by echocardiography in clinical practice: from conventional methods to new echocardiographic techniques. Sci. World J. 2014. https:\/\/doi.org\/10.1155\/2014\/451042.","journal-title":"Sci. World J."},{"issue":"6","key":"527_CR48","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1161\/CIRCHEARTFAILURE.114.001276","volume":"7","author":"A Rossi","year":"2014","unstructured":"Rossi, A., M. Gheorghiade, F. Triposkiadis, et al. Left atrium in heart failure with preserved ejection fraction: structure, function, and Significance. Circ. Heart Failure 7(6):1042\u20131049, 2014.","journal-title":"Circ. Heart Failure"},{"key":"527_CR49","doi-asserted-by":"crossref","unstructured":"Saha S, Islam M, Rahimi-Gorji M, et al. Aerosol particle transport and deposition in a CT-scan based mouth-throat model. Computer Methods and Programs in Biomedicine, Vol 180, 2019, 105010, AIP Conference Proceedings 2121, 040011,","DOI":"10.1063\/1.5115882"},{"issue":"3","key":"527_CR50","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.pcad.2005.06.014","volume":"48","author":"BA Schoonderwoerd","year":"2005","unstructured":"Schoonderwoerd, B. A., I. C. V. Gelder, D. J. V. Veldhuisen, et al. Electrical and structural remodeling: role in the genesis and maintenance of atrial fibrillation. Prog. Cardiovasc. Dis. 48(3):153\u2013168, 2005.","journal-title":"Prog. Cardiovasc. Dis."},{"issue":"10","key":"527_CR51","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1161\/01.CIR.0000055314.10801.4F","volume":"107","author":"U Schotten","year":"2003","unstructured":"Schotten, U. Electrical and contractile remodeling during the first days of atrial fibrillation go hand in hand. Circulation 107(10):1433\u20131439, 2003.","journal-title":"Circulation"},{"key":"527_CR52","first-page":"1","volume":"2014","author":"Z Shanshan","year":"2014","unstructured":"Shanshan, Z., S. Wanqing, Z. Zhiguo, et al. The role of Nrf2-mediated pathway in cardiac remodeling and heart failure. Oxid. Med. Cell. Long. 2014:1\u201316, 2014.","journal-title":"Oxid. Med. Cell. Long."},{"issue":"2","key":"527_CR53","first-page":"140","volume":"5","author":"XD Shao","year":"2014","unstructured":"Shao, X. D., L. Jun, J. L. Wei, et al. Can atrial myoelectric remodeling promote atrial fibrillation? Med. Contend 5(2):140\u2013146, 2014.","journal-title":"Med. Contend"},{"issue":"6","key":"527_CR54","first-page":"745","volume":"37","author":"Z Shao-Hua","year":"2013","unstructured":"Shao-Hua, Z., Z. Yu-Jiao, L. I. Zhi-Yuan, et al. Autonomic neural remodeling of pulmonary vein-left atrium junction in a prolonged right atrial pacing canine model. J. Shandong Univ. (Health Sciences) 37(6):745\u2013750, 2013.","journal-title":"J. Shandong Univ. (Health Sciences)"},{"issue":"8","key":"527_CR55","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1038\/sc.2017.30","volume":"55","author":"H Sharif","year":"2017","unstructured":"Sharif, H., L. Wainman, D. O\u2019Leary, et al. The effect of blood volume and volume loading on left ventricular diastolic function in individuals with spinal cord injury. Spinal Cord 55(8):753\u2013758, 2017.","journal-title":"Spinal Cord"},{"issue":"3","key":"527_CR56","doi-asserted-by":"crossref","first-page":"383a","DOI":"10.1016\/j.bpj.2017.11.2118","volume":"114","author":"U Srivastava","year":"2018","unstructured":"Srivastava, U., A. Bhattacharya, M. Boutjdir, et al. Mechanisms of atrial electrical remodeling in obese heart. Biophys. J . 114(3):383a, 2018.","journal-title":"Biophys. J ."},{"issue":"1","key":"527_CR57","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.jcmg.2016.11.003","volume":"10","author":"L Thomas","year":"2017","unstructured":"Thomas, L., and W. P. Abhayaratna. Left atrial reverse remodeling: mechanisms, evaluation, and clinical significance. Jacc Cardiovasc. Imaging 10(1):65, 2017.","journal-title":"Jacc Cardiovasc. Imaging"},{"issue":"2","key":"527_CR58","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1093\/cvr\/cvr052","volume":"90","author":"H Tuunanen","year":"2011","unstructured":"Tuunanen, H., and J. Knuuti. Metabolic remodelling in human heart failure. Cardiovasc. Res. 90(2):251\u2013257, 2011.","journal-title":"Cardiovasc. Res."},{"key":"527_CR59","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1038\/nature03952","volume":"437","author":"E Tzima","year":"2005","unstructured":"Tzima, E., M. Irani-Tehrani, W. B. Kiosses, et al. A mechanosensory complex that mediates the endothelial cell response to fluid shear stress. Nature 437:426\u2013431, 2005.","journal-title":"Nature"},{"issue":"2","key":"527_CR60","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.cardiores.2003.11.014","volume":"61","author":"M Vanbilsen","year":"2004","unstructured":"Vanbilsen, M., P. Smeets, A. Gilde, et al. Metabolic remodelling of the failing heart: the cardiac burn-out syndrome? Cardiovasc. Res. 61(2):218\u2013226, 2004.","journal-title":"Cardiovasc. Res."},{"issue":"4","key":"527_CR61","doi-asserted-by":"crossref","first-page":"265","DOI":"10.2459\/JCM.0b013e328354e458","volume":"14","author":"W Wang","year":"2013","unstructured":"Wang, W., H. T. Zhang, and X. L. Yang. Effect of matrix metalloproteinase and their inhibitors on atrial myocardial structural remodeling. J. Cardiovasc. Med. 14(4):265\u2013269, 2013.","journal-title":"J. Cardiovasc. Med."},{"issue":"1","key":"527_CR62","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1161\/CIRCHEARTFAILURE.109.931451","volume":"4","author":"D Westermann","year":"2011","unstructured":"Westermann, D., D. Lindner, M. Kasner, et al. Cardiac inflammation contributes to changes in the extracellular matrix in patients with heart failure and normal ejection fraction. Circ. Heart Fail 4(1):44\u201352.15, 2011.","journal-title":"Circ. Heart Fail"},{"issue":"7","key":"527_CR63","doi-asserted-by":"crossref","first-page":"1954","DOI":"10.1161\/01.CIR.92.7.1954","volume":"92","author":"MCEF Wijffels","year":"1995","unstructured":"Wijffels, M. C. E. F., C. J. H. J. Kirchhof, R. Dorland, et al. Atrial fibrillation begets atrial fibrillation: a study in awake chronically instrumented goats. Circulation 92(7):1954\u20131968, 1995.","journal-title":"Circulation"},{"issue":"1","key":"527_CR64","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.mehy.2012.10.009","volume":"80","author":"Y Xu","year":"2013","unstructured":"Xu, Y., D. Sharma, G. Li, et al. Atrial remodeling: New pathophysiological mechanism of atrial fibrillation. Medical Hypotheses 80(1):53\u201356.12, 2013.","journal-title":"Medical Hypotheses"},{"issue":"5","key":"527_CR65","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1016\/j.hrthm.2011.12.023","volume":"9","author":"L Yu","year":"2012","unstructured":"Yu, L., B. J. Scherlag, Y. Sha, et al. Interactions between atrial electrical remodeling and autonomic remodeling: How to break the vicious cycle. Heart Rhythm. 9(5):804\u2013809, 2012.","journal-title":"Heart Rhythm."},{"issue":"4","key":"527_CR66","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1002\/jmri.24633","volume":"41","author":"J Zajac","year":"2015","unstructured":"Zajac, J., J. Eriksson, P. Dyverfeldt, et al. Turbulent kinetic energy in normal and myopathic left ventricles. J. Magn. Reson. Imaging 41(4):1021\u20131029, 2015.","journal-title":"J. Magn. Reson. Imaging"},{"issue":"3","key":"527_CR67","doi-asserted-by":"crossref","first-page":"e0122674","DOI":"10.1371\/journal.pone.0122674","volume":"10","author":"Y Zhang","year":"2015","unstructured":"Zhang, Y., S. Zheng, Y. Geng, et al. MicroRNA profiling of atrial fibrillation in canines: MiR-206 modulates intrinsic cardiac autonomic nerve remodeling by regulating SOD1. PLoS ONE 10(3):e0122674, 2015.","journal-title":"PLoS ONE"}],"container-title":["Cardiovascular Engineering and Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13239-021-00527-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s13239-021-00527-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13239-021-00527-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T21:16:49Z","timestamp":1622582209000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s13239-021-00527-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,1]]},"references-count":67,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["527"],"URL":"https:\/\/doi.org\/10.1007\/s13239-021-00527-w","relation":{},"ISSN":["1869-408X","1869-4098"],"issn-type":[{"value":"1869-408X","type":"print"},{"value":"1869-4098","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3,1]]},"assertion":[{"value":"29 October 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 February 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 March 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}