{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T14:14:16Z","timestamp":1776867256634,"version":"3.51.2"},"reference-count":90,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T00:00:00Z","timestamp":1767571200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T00:00:00Z","timestamp":1767571200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100000084","name":"Directorate for Engineering","doi-asserted-by":"publisher","award":["CAREER 2049088"],"award-info":[{"award-number":["CAREER 2049088"]}],"id":[{"id":"10.13039\/100000084","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Northeastern University USA"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cardiovasc Eng Tech"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>\n                      <jats:bold>Purpose<\/jats:bold>\n                    <\/jats:title>\n                    <jats:p>Tricuspid valve chordae tendineae rupture is a valvular lesion that is often overlooked, though is postulated to be more prevalent than currently known. We examined the hemodynamics and biomechanical response of the tricuspid valve leaflets following chordae rupture to understand how acute changes in the post-rupture mechanical environment may contribute to long-term remodeling responses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>\n                      <jats:bold>Methods<\/jats:bold>\n                    <\/jats:title>\n                    <jats:p>Porcine valve leaflet deformation was studied in an intact heart in an ex vivo setup using sonomicrometry techniques before and after chordae rupture, which was induced by severing a chordae bundle connected to the septal leaflet.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>\n                      <jats:bold>Results<\/jats:bold>\n                    <\/jats:title>\n                    <jats:p>\n                      Following chordae rupture, pulmonary artery pressure dropped approximately 5 mmHg (\n                      <jats:inline-formula>\n                        <jats:alternatives>\n                          <jats:tex-math>$$p=0.048$$<\/jats:tex-math>\n                          <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\">\n                            <mml:mrow>\n                              <mml:mi>p<\/mml:mi>\n                              <mml:mo>=<\/mml:mo>\n                              <mml:mn>0.048<\/mml:mn>\n                            <\/mml:mrow>\n                          <\/mml:math>\n                        <\/jats:alternatives>\n                      <\/jats:inline-formula>\n                      ), indicating that valvular regurgitation occurred immediately after rupture. Mean maximum principal stretch of the septal leaflet increased 12% after rupture (\n                      <jats:inline-formula>\n                        <jats:alternatives>\n                          <jats:tex-math>$$p=0.006$$<\/jats:tex-math>\n                          <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\">\n                            <mml:mrow>\n                              <mml:mi>p<\/mml:mi>\n                              <mml:mo>=<\/mml:mo>\n                              <mml:mn>0.006<\/mml:mn>\n                            <\/mml:mrow>\n                          <\/mml:math>\n                        <\/jats:alternatives>\n                      <\/jats:inline-formula>\n                      ).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>\n                      <jats:bold>Conclusion<\/jats:bold>\n                    <\/jats:title>\n                    <jats:p>The immediate changes in post-rupture septal leaflet stretches show that chordae tendineae rupture acutely alters the biomechanical environment of the tricuspid valve, which may result in chronic tissue remodeling responses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>\n                      <jats:bold>Non-technical Summary<\/jats:bold>\n                    <\/jats:title>\n                    <jats:p>The tricuspid valve is one of the four valves in the heart. Rupture of supporting structures of the tricuspid valve leaflet, known as chordae tendineae, may be more common than previously thought. In this study, we used excised pig hearts to examine how chordae rupture affects valvular function. With our experimental beating heart system, we pumped fluid through the hearts under realistic conditions and measured changes in pressure and leaflet motion before and after chordae rupture. After rupture, we observed a change in pressures and leaflet motion, causing the valve to leak and become less efficient. These changes may influence how the valve functions over time.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s13239-025-00815-9","type":"journal-article","created":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T18:35:03Z","timestamp":1767638103000},"page":"223-236","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Chordae Rupture Alters Tricuspid Valve Leaflet Biomechanics"],"prefix":"10.1007","volume":"17","author":[{"given":"Julia","family":"Clarin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keyvan A.","family":"Khoiy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel D.","family":"Salinas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dipankar","family":"Biswas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kourosh T.","family":"Asgarian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francis","family":"Loth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3632-6195","authenticated-orcid":false,"given":"Rouzbeh","family":"Amini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,1,5]]},"reference":[{"key":"815_CR1","volume-title":"Carpentier\u2019s Reconstructive Valve Surgery E-Book","author":"A Carpentier","year":"2011","unstructured":"Carpentier, A., D. H. Adams, and F. Filsoufi. Carpentier\u2019s Reconstructive Valve Surgery E-Book. Maryland Heights: Elsevier Health Sciences, 2011."},{"issue":"10","key":"815_CR2","doi-asserted-by":"publisher","first-page":"867","DOI":"10.1016\/s1010-7940(96)80313-7","volume":"10","author":"F Maisano","year":"1996","unstructured":"Maisano, F., R. Lorusso, L. Sandrelli, L. Torracca, G. Coletti, G. La Canna, and O. Alfieri. Valve repair for traumatic tricuspid regurgitation. Eur. J. Cardio-thorac. Surg. 10(10):867\u2013873, 1996. https:\/\/doi.org\/10.1016\/s1010-7940(96)80313-7.","journal-title":"Eur. J. Cardio-thorac. Surg."},{"issue":"4","key":"815_CR3","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1093\/ejechocard\/jeq031","volume":"11","author":"P Lancellotti","year":"2010","unstructured":"Lancellotti, P., L. Moura, L. A. Pierard, E. Agricola, B. A. Popescu, C. Tribouilloy, A. Hagendorff, J.-L. Monin, L. Badano, J. L. Zamorano, On behalf of the European Association of Echocardiography, Reviewers:, D., Sicari, R., Vahanian, A., Roelandt, J.R.T.C. European Association of Echocardiography recommendations for the assessment of valvular regurgitation. Part 2: mitral and tricuspid regurgitation (native valve disease). Eur. J. Echocardiogr. 11(4):307\u2013332, 2010. https:\/\/doi.org\/10.1093\/ejechocard\/jeq031.","journal-title":"Eur. J. Echocardiogr."},{"issue":"12","key":"815_CR4","doi-asserted-by":"publisher","first-page":"626","DOI":"10.1016\/S1607-551X(09)70363-8","volume":"22","author":"S-J Lin","year":"2006","unstructured":"Lin, S.-J., C.-W. Chen, C.-J. Chou, K.-T. Liu, H.-M. Su, T.-H. Lin, W.-C. Voon, W.-T. Lai, and S.-H. Sheu. Traumatic tricuspid insufficiency with chordae tendinae rupture: a case report and literature review. Kaohsiung J. Med. Sci. 22(12):626\u2013629, 2006. https:\/\/doi.org\/10.1016\/S1607-551X(09)70363-8.","journal-title":"Kaohsiung J. Med. Sci."},{"issue":"6","key":"815_CR5","doi-asserted-by":"publisher","first-page":"1934","DOI":"10.1016\/j.athoracsur.2010.07.081","volume":"90","author":"W-G Ma","year":"2010","unstructured":"Ma, W.-G., G.-H. Luo, H.-S. Sun, J.-P. Xu, S.-S. Hu, and X.-D. Zhu. Surgical treatment of traumatic tricuspid insufficiency: experience in 13 cases. Ann. Thorac. Surg. 90(6):1934\u20131938, 2010. https:\/\/doi.org\/10.1016\/j.athoracsur.2010.07.081.","journal-title":"Ann. Thorac. Surg."},{"issue":"2","key":"815_CR6","doi-asserted-by":"publisher","first-page":"68","DOI":"10.17479\/jacs.2016.6.2.68","volume":"6","author":"J Yun Yong","year":"2016","unstructured":"Yun Yong, J., M. Jonghwan, L. Sang Hyun, K. Yeo Jin, A. Hyoeun, and P. Sung Yong. Undiagnosed traumatic tricuspid regurgitation identified by intraoperative transesophageal echocardiography. J. Acute Care Surg. 6(2):68\u201370, 2016.","journal-title":"J. Acute Care Surg."},{"issue":"1","key":"815_CR7","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1016\/j.acvd.2015.08.007","volume":"109","author":"O Huttin","year":"2016","unstructured":"Huttin, O., D. Voilliot, D. Mandry, C. Venner, Y. Juilli\u00e8re, and C. Selton-Suty. All you need to know about the tricuspid valve: tricuspid valve imaging and tricuspid regurgitation analysis. Arch. Cardiovasc. Dis. 109(1):67\u201380, 2016. https:\/\/doi.org\/10.1016\/j.acvd.2015.08.007.","journal-title":"Arch. Cardiovasc. Dis."},{"issue":"2","key":"815_CR8","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1253\/circj.CJ-09-0679","volume":"74","author":"J-W Lee","year":"2010","unstructured":"Lee, J.-W., J.-M. Song, J. P. Park, J. W. Lee, D.-H. Kang, and J.-K. Song. Long-term prognosis of isolated significant tricuspid regurgitation. Circ. J. 74(2):375\u2013380, 2010. https:\/\/doi.org\/10.1253\/circj.CJ-09-0679.","journal-title":"Circ. J."},{"issue":"2","key":"815_CR9","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1016\/j.jtcvs.2004.01.035","volume":"128","author":"D Messika-Zeitoun","year":"2004","unstructured":"Messika-Zeitoun, D., H. Thomson, M. Bellamy, C. Scott, C. Tribouilloy, J. Dearani, A. J. Tajik, H. Schaff, and M. Enriquez-Sarano. Medical and surgical outcome of tricuspid regurgitation caused by flail leaflets. J. Thorac. Cardiovasc. Surg. 128(2):296\u2013302, 2004. https:\/\/doi.org\/10.1016\/j.jtcvs.2004.01.035.","journal-title":"J. Thorac. Cardiovasc. Surg."},{"issue":"3","key":"815_CR10","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1097\/00063110-200209000-00010","volume":"9","author":"G Dounis","year":"2002","unstructured":"Dounis, G., E. Matsakas, J. Poularas, K. Papakonstantinou, A. Kalogeromitros, and A. Karabinis. Traumatic tricuspid insufficiency: a case report with a review of the literature. Eur. J. Emerg. Med. 9(3):258\u2013261, 2002.","journal-title":"Eur. J. Emerg. Med."},{"issue":"15","key":"815_CR11","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1007\/s00508-008-1012-7","volume":"120","author":"I Schuster","year":"2008","unstructured":"Schuster, I., S. Graf, U. Klaar, R. Seitelberger, G. Mundigler, and T. Binder. Heterogeneity of traumatic injury of the tricuspid valve: a report of four cases. Wiener klin. Wochenschr. 120(15):499\u2013503, 2008. https:\/\/doi.org\/10.1007\/s00508-008-1012-7.","journal-title":"Wiener klin. Wochenschr."},{"issue":"5","key":"815_CR12","doi-asserted-by":"publisher","first-page":"893","DOI":"10.1016\/S0022-5223(94)70188-1","volume":"108","author":"JAM Van Son","year":"1994","unstructured":"Van Son, J. A. M., G. K. Danielson, H. V. Schaff, and F. A. Miller. Traumatic tricuspid valve insufficiency. J. Thorac. Cardiovasc. Surg. 108(5):893\u2013898, 1994. https:\/\/doi.org\/10.1016\/S0022-5223(94)70188-1.","journal-title":"J. Thorac. Cardiovasc. Surg."},{"issue":"3","key":"815_CR13","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1378\/chest.92.3.429","volume":"92","author":"C Gayet","year":"1987","unstructured":"Gayet, C., B. Pierre, J.-P. Delahaye, G. Champsaur, X. Andre-Fouet, and P. Rueff. Traumatic tricuspid insufficiency. Chest. 92(3):429\u2013432, 1987. https:\/\/doi.org\/10.1378\/chest.92.3.429.","journal-title":"Chest"},{"issue":"3","key":"815_CR14","doi-asserted-by":"publisher","first-page":"799","DOI":"10.1016\/0002-8703(92)90300-K","volume":"124","author":"A Linka","year":"1992","unstructured":"Linka, A., M. Ritter, M. Turina, and R. Jenni. Acute tricuspid papillary muscle rupture following blunt chest trauma. Am. Heart J. 124(3):799\u2013802, 1992. https:\/\/doi.org\/10.1016\/0002-8703(92)90300-K.","journal-title":"Am. Heart J."},{"issue":"2","key":"815_CR15","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1016\/S1054-8807(01)00059-X","volume":"10","author":"J Dos Santos","year":"2001","unstructured":"Dos Santos, J., C. H. De Marchi, R. B. Bestetti, H. A. R. Corbucci, and P. R. Pavarino. Ruptured chordae tendineae of the posterior leaflet of the tricuspid valve as a cause of tricuspid regurgitation following blunt chest trauma. Cardiovasc. Pathol. 10(2):97\u201398, 2001. https:\/\/doi.org\/10.1016\/S1054-8807(01)00059-X.","journal-title":"Cardiovasc. Pathol."},{"issue":"2","key":"815_CR16","doi-asserted-by":"publisher","first-page":"320","DOI":"10.1016\/0003-4975(91)90816-9","volume":"51","author":"G Noera","year":"1991","unstructured":"Noera, G., M. Sanguinetti, P. Pensa, B. Biagi, A. Cremonesi, R. Lodi, A. Lessana, and C. Carbone. Tricuspid valve incompetence caused by nonpenetrating thoracic trauma. Ann. Thorac. Surg. 51(2):320\u2013322, 1991. https:\/\/doi.org\/10.1016\/0003-4975(91)90816-9.","journal-title":"Ann. Thorac. Surg."},{"issue":"3","key":"815_CR17","first-page":"195","volume":"4","author":"MJ Krasna","year":"1992","unstructured":"Krasna, M. J., and L. Flancbaum. Blunt cardiac trauma: clinical manifestations and management. Semin. Thorac. Cardiovasc. Surg. 4(3):195\u2013202, 1992.","journal-title":"Semin. Thorac. Cardiovasc. Surg."},{"issue":"1","key":"815_CR18","doi-asserted-by":"publisher","first-page":"15741","DOI":"10.1111\/echo.15741","volume":"41","author":"X Li","year":"2024","unstructured":"Li, X., and J. Hou. Severe tricuspid regurgitation with chordae tendinae rupture in CABG surgery. Echocardiography. 41(1):15741, 2024. https:\/\/doi.org\/10.1111\/echo.15741.","journal-title":"Echocardiography"},{"issue":"1","key":"815_CR19","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1016\/0002-9149(90)90748-P","volume":"66","author":"AC Braverman","year":"1990","unstructured":"Braverman, A. C., S. E. Coplen, G. H. Mudge, and R. T. Lee. Ruptured chordae tendineae of the tricuspid valve as a complication of endomyocardial biopsy in heart transplant patients. Am. J. Cardiol. 66(1):111\u2013113, 1990. https:\/\/doi.org\/10.1016\/0002-9149(90)90748-P.","journal-title":"Am. J. Cardiol."},{"issue":"2","key":"815_CR20","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1016\/j.euje.2006.11.006","volume":"9","author":"BS Emine","year":"2008","unstructured":"Emine, B. S., A. Murat, B. Mehmet, K. Mustafa, and I. Gokturk. Flail mitral and tricuspid valves due to myxomatous disease. Eur. J. Echocardiogr. 9(2):304\u2013305, 2008. https:\/\/doi.org\/10.1016\/j.euje.2006.11.006.","journal-title":"Eur. J. Echocardiogr."},{"issue":"5","key":"815_CR21","doi-asserted-by":"publisher","first-page":"1043","DOI":"10.1016\/j.jtcvs.2011.07.004","volume":"143","author":"CM Vassileva","year":"2012","unstructured":"Vassileva, C. M., J. Shabosky, T. Boley, S. Markwell, and S. Hazelrigg. Tricuspid valve surgery: the past 10 years from the Nationwide Inpatient Sample (NIS) database. J. Thorac. Cardiovasc. Surg. 143(5):1043\u20131049, 2012. https:\/\/doi.org\/10.1016\/j.jtcvs.2011.07.004.","journal-title":"J. Thorac. Cardiovasc. Surg."},{"issue":"2","key":"815_CR22","first-page":"91","volume":"9","author":"X-T Hou","year":"2006","unstructured":"Hou, X.-T., X. Meng, Q.-W. Zhou, J.-Q. Zhang, C.-L. Xu, and J.-G. Wang. Outcome of surgical treatment of post-traumatic tricuspid insufficiency. Chin. J. Traumatol. Zhonghua Chuang Shang Za Zhi. 9(2):91\u201393, 2006.","journal-title":"Chin. J. Traumatol. Zhonghua Chuang Shang Za Zhi"},{"issue":"6","key":"815_CR23","first-page":"651","volume":"6","author":"T Sugita","year":"1997","unstructured":"Sugita, T., S. Watarida, K. Katsuyama, Y. Nakajima, R. Yamamoto, and A. Mori. Valve repair with chordal replacement for traumatic tricuspid regurgitation. J. Heart Valve Dis. 6(6):651\u2013652, 1997.","journal-title":"J. Heart Valve Dis."},{"issue":"6","key":"815_CR24","doi-asserted-by":"publisher","first-page":"653","DOI":"10.1111\/j.1540-8175.2008.00701.x","volume":"25","author":"VK Reddy","year":"2008","unstructured":"Reddy, V. K., S. Nanda, N. Bandarupalli, K. R. Pothineni, and N. C. Nanda. Traumatic tricuspid papillary muscle and chordae rupture: emerging role of three-dimensional echocardiography. Echocardiography. 25(6):653\u2013657, 2008. https:\/\/doi.org\/10.1111\/j.1540-8175.2008.00701.x.","journal-title":"Echocardiography"},{"issue":"6","key":"815_CR25","doi-asserted-by":"publisher","first-page":"1410","DOI":"10.1016\/S0002-8703(05)80194-2","volume":"119","author":"T Hilton","year":"1990","unstructured":"Hilton, T., L. Mezei, and A. C. Pearson. Delayed rupture of tricuspid papillary muscle following blunt chest trauma. Am. Heart J. 119(6):1410\u20131412, 1990. https:\/\/doi.org\/10.1016\/S0002-8703(05)80194-2.","journal-title":"Am. Heart J."},{"issue":"5","key":"815_CR26","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1136\/heart.86.5.e12","volume":"86","author":"T Herbots","year":"2001","unstructured":"Herbots, T. Delayed post-traumatic tamponade together with rupture of the tricuspid valve in a 15 year old boy. Heart. 86(5):12, 2001. https:\/\/doi.org\/10.1136\/heart.86.5.e12.","journal-title":"Heart"},{"issue":"4","key":"815_CR27","first-page":"451","volume":"90","author":"P Richard","year":"1997","unstructured":"Richard, P., F. Vayre, P. Sabouret, I. Gandjbakhch, and J. P. Ollivier. Outcome of traumatic tricuspid insufficiency, treated surgically. Apropos of 9 cases. Arch. mal. coeur vaiss. 90(4):451\u2013456, 1997.","journal-title":"Arch. mal. coeur vaiss."},{"issue":"6","key":"815_CR28","doi-asserted-by":"publisher","first-page":"911","DOI":"10.1016\/0002-9149(66)90440-1","volume":"18","author":"RO Brandenburg","year":"1966","unstructured":"Brandenburg, R. O., D. C. McGoon, L. Campeau, and E. R. Giuliani. Traumatic rupture of the chordae tendineae of the tricuspid valve: Successful repair twenty-four years later. Am. J. Cardiol. 18(6):911\u2013915, 1966. https:\/\/doi.org\/10.1016\/0002-9149(66)90440-1.","journal-title":"Am. J. Cardiol."},{"issue":"45","key":"815_CR29","doi-asserted-by":"publisher","first-page":"4304","DOI":"10.1093\/eurheartj\/ehaa643","volume":"41","author":"J Dreyfus","year":"2020","unstructured":"Dreyfus, J., M. Flagiello, B. Bazire, F. Eggenspieler, F. Viau, E. Riant, Y. Mbaki, Y. Bohbot, D. Eyharts, T. Senage, H. Dubrulle, M. Nicol, F. Doguet, V. Nguyen, A. Coisne, T. Le Tourneau, Y. Lavie-Badie, C. Tribouilloy, E. Donal, J. Tomasi, G. Habib, C. Selton-Suty, R. Raffoul, B. Iung, J.-F. Obadia, and D. Messika-Zeitoun. Isolated tricuspid valve surgery: impact of aetiology and clinical presentation on outcomes. Eur. Heart J. 41(45):4304\u20134317, 2020. https:\/\/doi.org\/10.1093\/eurheartj\/ehaa643.","journal-title":"Eur. Heart J."},{"issue":"6","key":"815_CR30","doi-asserted-by":"publisher","first-page":"032999","DOI":"10.1161\/JAHA.123.032999","volume":"13","author":"M Ambrosino","year":"2024","unstructured":"Ambrosino, M., M. Sangoi, N. Monzer, B. Irving, P. Fiorilli, B. Khazan, and S. Goldberg. Tricuspid regurgitation: a review of current interventional management. JAHA. 13(6):032999, 2024. https:\/\/doi.org\/10.1161\/JAHA.123.032999.","journal-title":"JAHA"},{"issue":"10","key":"815_CR31","doi-asserted-by":"publisher","first-page":"104504","DOI":"10.1115\/1.4034426","volume":"138","author":"K Amini Khoiy","year":"2016","unstructured":"Amini Khoiy, K., and R. Amini. On the biaxial mechanical response of porcine tricuspid valve leaflets. J. Biomech. Eng. 138(10):104504, 2016. https:\/\/doi.org\/10.1115\/1.4034426.","journal-title":"J. Biomech. Eng."},{"key":"815_CR32","doi-asserted-by":"publisher","first-page":"109462","DOI":"10.1016\/j.jbiomech.2019.109462","volume":"98","author":"SD Salinas","year":"2020","unstructured":"Salinas, S. D., M. M. Clark, and R. Amini. The effects of $$- 80^{\\circ }$$C short-term storage on the mechanical response of tricuspid valve leaflets. J. Biomech. 98:109462, 2020.","journal-title":"J. Biomech."},{"issue":"3","key":"815_CR33","doi-asserted-by":"publisher","first-page":"70","DOI":"10.3390\/bioengineering6030070","volume":"6","author":"SD Salinas","year":"2019","unstructured":"Salinas, S. D., M. M. Clark, and R. Amini. Mechanical response changes in porcine tricuspid valve anterior leaflet under osmotic-induced swelling. Bioengineering. 6(3):70, 2019.","journal-title":"Bioengineering"},{"issue":"9","key":"815_CR34","doi-asserted-by":"publisher","first-page":"94503","DOI":"10.1115\/1.4040126","volume":"140","author":"K Amini Khoiy","year":"2018","unstructured":"Amini Khoiy, K., A. D. Pant, and R. Amini. Quantification of material constants for a phenomenological constitutive model of porcine tricuspid valve leaflets for simulation applications. J. Biomech. Eng. 140(9):94503\u201394511, 2018. https:\/\/doi.org\/10.1115\/1.4040126.","journal-title":"J. Biomech. Eng."},{"key":"815_CR35","doi-asserted-by":"publisher","first-page":"524","DOI":"10.1016\/j.actbio.2019.05.074","volume":"94","author":"VS Thomas","year":"2019","unstructured":"Thomas, V. S., V. Lai, and R. Amini. A computational multi-scale approach to investigate mechanically-induced changes in tricuspid valve anterior leaflet microstructure. Acta Biomater. 94:524\u2013535, 2019.","journal-title":"Acta Biomater."},{"key":"815_CR36","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1016\/j.actbio.2017.11.040","volume":"67","author":"AD Pant","year":"2018","unstructured":"Pant, A. D., V. S. Thomas, A. L. Black, T. Verba, J. G. Lesicko, and R. Amini. Pressure-induced microstructural changes in porcine tricuspid valve leaflets. Acta Biomater. 67:248\u2013258, 2018. https:\/\/doi.org\/10.1016\/j.actbio.2017.11.040.","journal-title":"Acta Biomater."},{"key":"815_CR37","unstructured":"Salinas, S. D. Multiscale biomechanics and mechanobiology of the tricuspid valve leaflets. PhD Thesis, Northeastern University, 2022."},{"issue":"5","key":"815_CR38","doi-asserted-by":"publisher","first-page":"0267131","DOI":"10.1371\/journal.pone.0267131","volume":"17","author":"SD Salinas","year":"2022","unstructured":"Salinas, S. D., Y. M. Farra, K. Amini Khoiy, J. Houston, C.-H. Lee, C. Bellini, and R. Amini. The role of elastin on the mechanical properties of the anterior leaflet in porcine tricuspid valves. PLoS ONE. 17(5):0267131, 2022.","journal-title":"PLoS ONE"},{"key":"815_CR39","doi-asserted-by":"publisher","first-page":"031023","DOI":"10.1115\/1.4066002","volume":"3","author":"M Pakzadmanesh","year":"2024","unstructured":"Pakzadmanesh, M., S. D. Salinas, V. S. Thomas, T. Jennings, H. DelCiello, A. I. Vargas, J. Clarin, and R. Amini. Mechanically induced deformation of nuclei in the tricuspid valve interstitial cells: experimental measurements and multi-scale computational simulation. ASME Open J. Eng. 3:031023, 2024.","journal-title":"ASME Open J. Eng."},{"issue":"1","key":"815_CR40","first-page":"127","volume":"71","author":"IE Willems","year":"1994","unstructured":"Willems, I. E., M. G. Havenith, J. F. Smits, and M. J. Daemen. Structural alterations in heart valves during left ventricular pressure overload in the rat. Lab. Investig. J. Tech. Methods Pathol. 71(1):127\u2013133, 1994.","journal-title":"Lab. Investig. J. Tech. Methods Pathol."},{"issue":"14 Suppl 1","key":"815_CR41","first-page":"243","volume":"118","author":"EH Stephens","year":"2008","unstructured":"Stephens, E. H., T. C. Nguyen, A. Itoh, N. B. Ingels, D. C. Miller, and K. J. Grande-Allen. The effects of mitral regurgitation alone are sufficient for leaflet remodeling. Circulation. 118(14 Suppl 1):243\u2013249, 2008.","journal-title":"Circulation"},{"issue":"135","key":"815_CR42","doi-asserted-by":"publisher","first-page":"20170580","DOI":"10.1098\/rsif.2017.0580","volume":"14","author":"S Ayoub","year":"2017","unstructured":"Ayoub, S., C.-H. Lee, K. H. Driesbaugh, W. Anselmo, C. T. Hughes, G. Ferrari, R. C. Gorman, J. H. Gorman, and M. S. Sacks. Regulation of valve interstitial cell homeostasis by mechanical deformation: implications for heart valve disease and surgical repair. J. R. Soc. Interface. 14(135):20170580, 2017. https:\/\/doi.org\/10.1098\/rsif.2017.0580.","journal-title":"J. R. Soc. Interface"},{"issue":"11","key":"815_CR43","doi-asserted-by":"publisher","first-page":"0206744","DOI":"10.1371\/journal.pone.0206744","volume":"13","author":"K Amini Khoiy","year":"2018","unstructured":"Amini Khoiy, K., K. T. Asgarian, F. Loth, and R. Amini. Dilation of tricuspid valve annulus immediately after rupture of chordae tendineae in ex vivo porcine hearts. PLoS ONE. 13(11):0206744, 2018.","journal-title":"PLoS ONE"},{"issue":"11","key":"815_CR44","doi-asserted-by":"publisher","first-page":"111006","DOI":"10.1115\/1.4034621","volume":"138","author":"K Amini Khoiy","year":"2016","unstructured":"Amini Khoiy, K., D. Biswas, T. N. Decker, K. T. Asgarian, F. Loth, and R. Amini. Surface strains of porcine tricuspid valve septal leaflets measured in ex vivo beating hearts. J. Biomech. Eng. 138(11):111006, 2016.","journal-title":"J. Biomech. Eng."},{"key":"815_CR45","unstructured":"International Organization for Standardization. ISO 5840-1:2021\u2014Cardiovascular Implants\u2014Cardiac Valve Prostheses\u2014Part 1: General Requirements. ISO, 2021. https:\/\/www.iso.org\/standard\/80719.html."},{"key":"815_CR46","doi-asserted-by":"publisher","first-page":"021032","DOI":"10.1115\/1.4062477","volume":"2","author":"J Clarin","year":"2023","unstructured":"Clarin, J., D. Dang, L. Santos, and R. Amini. Mechanical characterization of porcine tricuspid valve anterior leaflets over time: applications to ex vivo studies. ASME Open J. Eng. 2:021032, 2023.","journal-title":"ASME Open J. Eng."},{"issue":"5","key":"815_CR47","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1016\/j.jtcvs.2023.04.003","volume":"166","author":"A Iwasieczko","year":"2023","unstructured":"Iwasieczko, A., T. Jazwiec, M. Gaddam, B. Gaweda, M. Piekarska, M. Solarewicz, M. K. Rausch, and T. A. Timek. Septal annular dilation in chronic ovine functional tricuspid regurgitation. J. Thorac. Cardiovasc. Surg. 166(5):393\u2013403, 2023.","journal-title":"J. Thorac. Cardiovasc. Surg."},{"issue":"4","key":"815_CR48","doi-asserted-by":"publisher","first-page":"1369","DOI":"10.1016\/j.athoracsur.2006.03.117","volume":"82","author":"MS Sacks","year":"2006","unstructured":"Sacks, M. S., Y. Enomoto, J. R. Graybill, W. D. Merryman, A. Zeeshan, A. P. Yoganathan, R. J. Levy, R. C. Gorman, and J. H. Gorman III. In vivo dynamic deformation of the mitral valve anterior leaflet. Ann. Thorac. Surg. 82(4):1369\u20131377, 2006.","journal-title":"Ann. Thorac. Surg."},{"issue":"7","key":"815_CR49","doi-asserted-by":"publisher","first-page":"1455","DOI":"10.1007\/s10439-012-0524-5","volume":"40","author":"R Amini","year":"2012","unstructured":"Amini, R., C. E. Eckert, K. Koomalsingh, J. McGarvey, M. Minakawa, J. H. Gorman, R. C. Gorman, and M. S. Sacks. On the in vivo deformation of the mitral valve anterior leaflet: effects of annular geometry and referential configuration. Ann. Biomed. Eng. 40(7):1455\u20131467, 2012.","journal-title":"Ann. Biomed. Eng."},{"issue":"3","key":"815_CR50","doi-asserted-by":"publisher","first-page":"31003","DOI":"10.1115\/1.4026105","volume":"136","author":"R Amini","year":"2014","unstructured":"Amini, R., C. A. Voycheck, and R. E. Debski. A method for predicting collagen fiber realignment in non-planar tissue surfaces as applied to glenohumeral capsule during clinically relevant deformation. J. Biomech. Eng. 136(3):31003, 2014.","journal-title":"J. Biomech. Eng."},{"issue":"6","key":"815_CR51","doi-asserted-by":"publisher","first-page":"61010","DOI":"10.1115\/1.2979866","volume":"130","author":"BA Filas","year":"2008","unstructured":"Filas, B. A., A. K. Knutsen, P. V. Bayly, and L. A. Taber. A new method for measuring deformation of folding surfaces during morphogenesis. J. Biomech. Eng. 130(6):61010, 2008.","journal-title":"J. Biomech. Eng."},{"key":"815_CR52","unstructured":"The Jamovi Project: Jamovi (Version 2.6), 2024. https:\/\/www.jamovi.org."},{"key":"815_CR53","unstructured":"R Core Team. R: A Language and Environment for Statistical Computing (Version 4.4). R Core Team, 2024. https:\/\/cran.r-project.org."},{"key":"815_CR54","unstructured":"Singmann, H. afex: Analysis of Factorial Experiments (R Package), 2023. https:\/\/cran.r-project.org\/package=afex."},{"issue":"2","key":"815_CR55","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1016\/S0008-6363(97)00038-2","volume":"34","author":"C Greyson","year":"1997","unstructured":"Greyson, C., Y. Xu, J. Cohen, and G. G. Schwartz. Right ventricular dysfunction persists following brief right ventricular pressure overload. Cardiovasc. Res. 34(2):281\u2013288, 1997. (S0008636397000382 [pii])","journal-title":"Cardiovasc. Res."},{"issue":"5","key":"815_CR56","doi-asserted-by":"publisher","first-page":"1414","DOI":"10.1152\/ajpheart.2000.278.5.H1414","volume":"278","author":"C Greyson","year":"2000","unstructured":"Greyson, C., Y. Xu, L. Lu, and G. G. Schwartz. Right ventricular pressure and dilation during pressure overload determine dysfunction after pressure overload. Am. J. Physiol. Heart Circ. Physiol. 278(5):1414\u20131420, 2000.","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"issue":"2","key":"815_CR57","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1016\/j.ejcts.2008.09.010","volume":"35","author":"JD Schmitto","year":"2009","unstructured":"Schmitto, J. D., H. Doerge, H. Post, M. Coulibaly, C. Sellin, A. F. Popov, S. Sossalla, and F. A. Schoendube. Progressive right ventricular failure is not explained by myocardial ischemia in a pig model of right ventricular pressure overload. Eur. J. Cardiothorac. Surg. 35(2):229\u2013234, 2009. https:\/\/doi.org\/10.1016\/j.ejcts.2008.09.010.","journal-title":"Eur. J. Cardiothorac. Surg."},{"issue":"6 Pt 2","key":"815_CR58","first-page":"1994","volume":"276","author":"SB Solomon","year":"1999","unstructured":"Solomon, S. B., and S. A. Glantz. Regional ischemia increases sensitivity of left ventricular relaxation to volume in pigs. Am. J. Physiol. 276(6 Pt 2):1994\u20132005, 1999.","journal-title":"Am. J. Physiol."},{"key":"815_CR59","volume-title":"Cardiovascular Physiology","author":"D Mohrman","year":"2006","unstructured":"Mohrman, D., and L. J. Heller. Cardiovascular Physiology. Columbus: McGraw-Hill Medical, 2006."},{"issue":"5","key":"815_CR60","doi-asserted-by":"publisher","first-page":"0232374","DOI":"10.1371\/journal.pone.0232374","volume":"15","author":"S Clauss","year":"2020","unstructured":"Clauss, S., D. Sch\u00fcttler, C. Bleyer, J. Vlcek, M. Shakarami, P. Tomsits, S. Schneider, F. Maderspacher, K. Chataut, A. Trebo, C. Wang, J. Kleeberger, R. Xia, E. Baloch, B. Hildebrand, S. Massberg, R. Wakili, and S. K\u00e4\u00e4b. Characterization of a porcine model of atrial arrhythmogenicity in the context of ischaemic heart failure. PLoS ONE. 15(5):0232374, 2020. https:\/\/doi.org\/10.1371\/journal.pone.0232374.","journal-title":"PLoS ONE"},{"issue":"1","key":"815_CR61","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1136\/hrt.59.1.23","volume":"59","author":"AN Redington","year":"1988","unstructured":"Redington, A. N., H. H. Gray, M. E. Hodson, M. L. Rigby, and P. J. Oldershaw. Characterisation of the normal right ventricular pressure\u2013volume relation by biplane angiography and simultaneous micromanometer pressure measurements. Br. Heart J. 59(1):23\u201330, 1988.","journal-title":"Br. Heart J."},{"key":"815_CR62","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1016\/j.jmbbm.2016.05.034","volume":"62","author":"K Zuo","year":"2016","unstructured":"Zuo, K., T. Pham, K. Li, C. Martin, Z. He, and W. Sun. Characterization of biomechanical properties of aged human and ovine mitral valve chordae tendineae. J. Mech. Behav. Biomed. Mater. 62:607\u2013618, 2016. https:\/\/doi.org\/10.1016\/j.jmbbm.2016.05.034.","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"815_CR63","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1016\/j.dib.2018.09.073","volume":"21","author":"S Jett","year":"2018","unstructured":"Jett, S., D. Laurence, R. Kunkel, A. R. Babu, K. Kramer, R. Baumwart, R. Towner, Y. Wu, and C.-H. Lee. Biaxial mechanical data of porcine atrioventricular valve leaflets. Data Brief. 21:358\u2013363, 2018.","journal-title":"Data Brief"},{"key":"815_CR64","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1016\/j.jbiomech.2018.11.015","volume":"83","author":"D Laurence","year":"2019","unstructured":"Laurence, D., C. Ross, S. Jett, C. Johns, A. Echols, R. Baumwart, R. Towner, J. Liao, P. Bajona, and Y. Wu. An investigation of regional variations in the biaxial mechanical properties and stress relaxation behaviors of porcine atrioventricular heart valve leaflets. J. Biomech. 83:16\u201327, 2019.","journal-title":"J. Biomech."},{"key":"815_CR65","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1016\/j.actbio.2017.03.026","volume":"54","author":"T Pham","year":"2017","unstructured":"Pham, T., F. Sulejmani, E. Shin, D. Wang, and W. Sun. Quantification and comparison of the mechanical properties of four human cardiac valves. Acta Biomater. 54:345\u2013355, 2017.","journal-title":"Acta Biomater."},{"issue":"6","key":"815_CR66","doi-asserted-by":"publisher","first-page":"1591","DOI":"10.1002\/jbm.a.34099","volume":"100","author":"C Martin","year":"2012","unstructured":"Martin, C., and W. Sun. Biomechanical characterization of aortic valve tissue in humans and common animal models. J. Biomed. Mater. Res. A. 100(6):1591\u20131599, 2012.","journal-title":"J. Biomed. Mater. Res. A"},{"issue":"5","key":"815_CR67","first-page":"432","volume":"53","author":"PP Lelovas","year":"2014","unstructured":"Lelovas, P. P., N. G. Kostomitsopoulos, and T. T. Xanthos. A comparative anatomic and physiologic overview of the porcine heart. J. Am. Assoc. Lab. Anim. Sci. 53(5):432\u2013438, 2014.","journal-title":"J. Am. Assoc. Lab. Anim. Sci."},{"issue":"5","key":"815_CR68","doi-asserted-by":"publisher","first-page":"1351","DOI":"10.1007\/s10237-019-01148-y","volume":"18","author":"M Mathur","year":"2019","unstructured":"Mathur, M., T. Jazwiec, W. D. Meador, M. Malinowski, M. Goehler, H. Ferguson, T. A. Timek, and M. K. Rausch. Tricuspid valve leaflet strains in the beating ovine heart. Biomech. Model. Mechanobiol. 18(5):1351\u20131361, 2019. https:\/\/doi.org\/10.1007\/s10237-019-01148-y.","journal-title":"Biomech. Model. Mechanobiol."},{"issue":"6","key":"815_CR69","doi-asserted-by":"publisher","first-page":"1149","DOI":"10.1016\/j.jbiomech.2011.01.020","volume":"44","author":"MK Rausch","year":"2011","unstructured":"Rausch, M. K., W. Bothe, J.-P.E. Kvitting, S. G\u00f6ktepe, D. C. Miller, and E. Kuhl. In vivo dynamic strains of the ovine anterior mitral valve leaflet. J. Biomech. 44(6):1149\u20131157, 2011.","journal-title":"J. Biomech."},{"issue":"3","key":"815_CR70","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1007\/s10439-017-1961-y","volume":"46","author":"MK Rausch","year":"2018","unstructured":"Rausch, M. K., M. Malinowski, P. Wilton, A. Khaghani, and T. A. Timek. Engineering analysis of tricuspid annular dynamics in the beating ovine heart. Ann. Biomed. Eng. 46(3):443\u2013451, 2018. https:\/\/doi.org\/10.1007\/s10439-017-1961-y.","journal-title":"Ann. Biomed. Eng."},{"issue":"4","key":"815_CR71","doi-asserted-by":"publisher","first-page":"1037","DOI":"10.1016\/j.jtcvs.2010.05.039","volume":"141","author":"H Fawzy","year":"2011","unstructured":"Fawzy, H., K. Fukamachi, C. D. Mazer, A. Harrington, D. Latter, D. Bonneau, and L. Errett. Complete mapping of the tricuspid valve apparatus using three-dimensional sonomicrometry. J. Thorac. Cardiovasc. Surg. 141(4):1037\u20131043, 2011.","journal-title":"J. Thorac. Cardiovasc. Surg."},{"issue":"6","key":"815_CR72","doi-asserted-by":"publisher","first-page":"1804","DOI":"10.1016\/j.athoracsur.2018.05.057","volume":"106","author":"M Malinowski","year":"2018","unstructured":"Malinowski, M., H. Schubert, J. Wodarek, H. Ferguson, L. Eberhart, D. Langholz, T. Jazwiec, M. K. Rausch, and T. A. Timek. Tricuspid annular geometry and strain after suture annuloplasty in acute ovine right heart failure. Ann. Thorac. Surg. 106(6):1804\u20131811, 2018. https:\/\/doi.org\/10.1016\/j.athoracsur.2018.05.057.","journal-title":"Ann. Thorac. Surg."},{"key":"815_CR73","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1016\/j.jbiomech.2018.01.016","volume":"69","author":"CA Guertler","year":"2018","unstructured":"Guertler, C. A., R. J. Okamoto, J. L. Schmidt, A. A. Badachhape, C. L. Johnson, and P. V. Bayly. Mechanical properties of porcine brain tissue in vivo and ex vivo estimated by MR elastography. J. Biomech. 69:10\u201318, 2018. https:\/\/doi.org\/10.1016\/j.jbiomech.2018.01.016.","journal-title":"J. Biomech."},{"issue":"2","key":"815_CR74","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1016\/j.echo.2018.08.010","volume":"32","author":"KA Dumont","year":"2019","unstructured":"Dumont, K. A., J. P. Kvitting, J. S. Karlsen, E. W. Remme, J. Hausken, R. Lundblad, A. E. Fiane, and S. Urheim. Validation of a holographic display for quantification of mitral annular dynamics by three-dimensional echocardiography. J. Am. Soc. Echocardiogr. 32(2):303\u20133164, 2019. https:\/\/doi.org\/10.1016\/j.echo.2018.08.010.","journal-title":"J. Am. Soc. Echocardiogr."},{"issue":"9","key":"815_CR75","doi-asserted-by":"publisher","first-page":"448","DOI":"10.4070\/kcj.2010.40.9.448","volume":"40","author":"J-M Song","year":"2010","unstructured":"Song, J.-M., M.-K. Jang, Y.-J. Kim, D.-H. Kim, D.-H. Kang, and J.-K. Song. Right ventricular remodeling determines tricuspid valve geometry and the severity of functional tricuspid regurgitation: a real-time 3-dimensional echocardiography study. Korean Circ. J. 40(9):448, 2010. https:\/\/doi.org\/10.4070\/kcj.2010.40.9.448.","journal-title":"Korean Circ. J."},{"key":"815_CR76","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1016\/j.jmbbm.2018.07.024","volume":"87","author":"S Jett","year":"2018","unstructured":"Jett, S., D. Laurence, R. Kunkel, A. R. Babu, K. Kramer, R. Baumwart, R. Towner, Y. Wu, and C.-H. Lee. An investigation of the anisotropic mechanical properties and anatomical structure of porcine atrioventricular heart valves. J. Mech. Behav. Biomed. Mater. 87:155\u2013171, 2018. https:\/\/doi.org\/10.1016\/j.jmbbm.2018.07.024.","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"815_CR77","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1016\/j.actbio.2018.12.029","volume":"85","author":"A Pokutta-Paskaleva","year":"2019","unstructured":"Pokutta-Paskaleva, A., F. Sulejmani, M. DelRocini, and W. Sun. Comparative mechanical, morphological, and microstructural characterization of porcine mitral and tricuspid leaflets and chordae tendineae. Acta Biomater. 85:241\u2013252, 2019. https:\/\/doi.org\/10.1016\/j.actbio.2018.12.029.","journal-title":"Acta Biomater."},{"key":"815_CR78","doi-asserted-by":"publisher","unstructured":"Meador, W. D., M. Mathur, and M. K. Rausch. Tricuspid valve biomechanics: a brief review. In: Advances in Heart Valve Biomechanics. Cham: Springer, 2018, pp. 105\u2013114. https:\/\/doi.org\/10.1007\/978-3-030-01993-8_5.","DOI":"10.1007\/978-3-030-01993-8_5"},{"issue":"8","key":"815_CR79","doi-asserted-by":"publisher","first-page":"1112","DOI":"10.1007\/s10439-018-2024-8","volume":"46","author":"F Kong","year":"2018","unstructured":"Kong, F., T. Pham, C. Martin, R. McKay, C. Primiano, S. Hashim, S. Kodali, and W. Sun. Finite element analysis of tricuspid valve deformation from multi-slice computed tomography images. Ann. Biomed. Eng. 46(8):1112\u20131127, 2018. https:\/\/doi.org\/10.1007\/s10439-018-2024-8.","journal-title":"Ann. Biomed. Eng."},{"issue":"4","key":"815_CR80","doi-asserted-by":"publisher","first-page":"1452","DOI":"10.1016\/j.jtcvs.2018.08.110","volume":"157","author":"M Malinowski","year":"2019","unstructured":"Malinowski, M., T. Jazwiec, M. Goehler, N. Quay, J. Bush, S. Jovinge, M. K. Rausch, and T. A. Timek. Sonomicrometry-derived 3-dimensional geometry of the human tricuspid annulus. J. Thorac. Cardiovasc. Surg. 157(4):1452-1461.e1, 2019. https:\/\/doi.org\/10.1016\/j.jtcvs.2018.08.110.","journal-title":"J. Thorac. Cardiovasc. Surg."},{"issue":"7","key":"815_CR81","doi-asserted-by":"publisher","first-page":"3346","DOI":"10.1002\/cnm.3346","volume":"36","author":"DW Laurence","year":"2020","unstructured":"Laurence, D. W., E. L. Johnson, M.-C. Hsu, R. Baumwart, A. Mir, H. M. Burkhart, G. A. Holzapfel, Y. Wu, and C.-H. Lee. A pilot in silico modeling-based study of the pathological effects on the biomechanical function of tricuspid valves. Int. J. Numer. Methods Biomed. Eng. 36(7):3346, 2020. https:\/\/doi.org\/10.1002\/cnm.3346.","journal-title":"Int. J. Numer. Methods Biomed. Eng."},{"issue":"6","key":"815_CR82","doi-asserted-by":"publisher","first-page":"1422","DOI":"10.1007\/s10439-019-02243-y","volume":"47","author":"S Singh-Gryzbon","year":"2019","unstructured":"Singh-Gryzbon, S., V. Sadri, M. Toma, E. L. Pierce, Z. A. Wei, and A. P. Yoganathan. Development of a computational method for simulating tricuspid valve dynamics. Ann. Biomed. Eng. 47(6):1422\u20131434, 2019. https:\/\/doi.org\/10.1007\/s10439-019-02243-y.","journal-title":"Ann. Biomed. Eng."},{"issue":"2","key":"815_CR83","doi-asserted-by":"publisher","first-page":"47","DOI":"10.3390\/bioengineering6020047","volume":"6","author":"C-H Lee","year":"2019","unstructured":"Lee, C.-H., D. W. Laurence, C. J. Ross, K. E. Kramer, A. R. Babu, E. L. Johnson, M.-C. Hsu, A. Aggarwal, A. Mir, H. M. Burkhart, R. A. Towner, R. Baumwart, and Y. Wu. Mechanics of the tricuspid valve\u2014from clinical diagnosis\/treatment, in vivo and in vitro investigations, to patient-specific biomechanical modeling. Bioengineering. 6(2):47, 2019. https:\/\/doi.org\/10.3390\/bioengineering6020047.","journal-title":"Bioengineering"},{"key":"815_CR84","doi-asserted-by":"publisher","DOI":"10.35119\/aivo.v1i1.140","author":"AD Pant","year":"2025","unstructured":"Pant, A. D., F. Sebastian, K. Khoiy, R. Repetto, S. Dorairaj, and R. Amini. Impact of pupillary dilation on the efficacy of laser peripheral iridotomy. Artif. Intell. Vis. Ophthalmol. 2025. https:\/\/doi.org\/10.35119\/aivo.v1i1.140.","journal-title":"Artif. Intell. Vis. Ophthalmol."},{"issue":"3","key":"815_CR85","doi-asserted-by":"publisher","first-page":"1237","DOI":"10.1002\/mrm.28490","volume":"85","author":"BST Nwotchouang","year":"2021","unstructured":"Nwotchouang, B. S. T., M. S. Eppelheimer, D. Biswas, S. H. Pahlavian, X. Zhong, J. N. Oshinski, D. L. Barrow, R. Amini, and F. Loth. Accuracy of cardiac-induced brain motion measurement using displacement-encoding with stimulated echoes (DENSE) magnetic resonance imaging (MRI): a phantom study. Magn. Reson. Med. 85(3):1237\u20131247, 2021.","journal-title":"Magn. Reson. Med."},{"issue":"4","key":"815_CR86","doi-asserted-by":"publisher","first-page":"044501","DOI":"10.1115\/1.4067699","volume":"147","author":"T Jennings","year":"2025","unstructured":"Jennings, T., R. Amini, and S. M\u00fcft\u00fc. Toward a consistent framework for describing the free vibration modes of the brain. J. Biomech. Eng. 147(4):044501, 2025.","journal-title":"J. Biomech. Eng."},{"issue":"6","key":"815_CR87","doi-asserted-by":"publisher","first-page":"060906","DOI":"10.1115\/1.4064032","volume":"146","author":"F Sebastian","year":"2024","unstructured":"Sebastian, F., A. I. Vargas, J. Clarin, A. Hurgoi, and R. Amini. Meta data analysis of sex distribution of study samples reported in summer biomechanics, bioengineering, and biotransport annual conference abstracts. J. Biomech. Eng. 146(6):060906, 2024.","journal-title":"J. Biomech. Eng."},{"issue":"4","key":"815_CR88","doi-asserted-by":"publisher","first-page":"946","DOI":"10.1007\/s10439-025-03677-3","volume":"53","author":"T Jennings","year":"2025","unstructured":"Jennings, T., A. Tillman, D. Mukasa, M. Marchev, S. M\u00fcft\u00fc, and R. Amini. Measurement and assessment of head-to-helmet contact forces. Ann. Biomed. Eng. 53(4):946, 2025.","journal-title":"Ann. Biomed. Eng."},{"key":"815_CR89","doi-asserted-by":"publisher","DOI":"10.1115\/1.4068677","volume":"4","author":"F Sebastian","year":"2025","unstructured":"Sebastian, F., H. DelCiello, A. D. Pant, M. J. Girard, V. Pathak-Ray, S. K. Dorairaj, and R. Amini. Image-based inverse modeling analysis of iris stiffness across sex in patients with a history of primary angle-closure disease. ASME Open J. Eng.4:041013, 2025.","journal-title":"ASME Open J. Eng."},{"issue":"7","key":"815_CR90","doi-asserted-by":"publisher","first-page":"071004","DOI":"10.1115\/1.4064744","volume":"146","author":"AI Vargas","year":"2024","unstructured":"Vargas, A. I., S. A. Tarraf, T. Jennings, C. Bellini, and R. Amini. Vascular remodeling during late-gestation pregnancy: an in vitro assessment of the murine ascending thoracic aorta. J. Biomech. Eng. 146(7):071004, 2024. https:\/\/doi.org\/10.1115\/1.4064744.","journal-title":"J. Biomech. Eng."}],"container-title":["Cardiovascular Engineering and Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13239-025-00815-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s13239-025-00815-9","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13239-025-00815-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T13:22:09Z","timestamp":1776864129000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s13239-025-00815-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,5]]},"references-count":90,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["815"],"URL":"https:\/\/doi.org\/10.1007\/s13239-025-00815-9","relation":{},"ISSN":["1869-408X","1869-4098"],"issn-type":[{"value":"1869-408X","type":"print"},{"value":"1869-4098","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,5]]},"assertion":[{"value":"3 April 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 December 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 January 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no relevant financial or non-financial interests to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed Consent"}}]}}