{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T20:10:55Z","timestamp":1773864655589,"version":"3.50.1"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2017,11,15]],"date-time":"2017-11-15T00:00:00Z","timestamp":1510704000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Insights Imaging"],"published-print":{"date-parts":[[2018,2]]},"DOI":"10.1007\/s13244-017-0579-9","type":"journal-article","created":{"date-parts":[[2017,11,15]],"date-time":"2017-11-15T09:42:46Z","timestamp":1510738966000},"page":"47-58","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Role of magnetic resonance imaging in the management of perianal Crohn\u2019s disease"],"prefix":"10.1007","volume":"9","author":[{"given":"Jose C.","family":"Gallego","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana","family":"Echarri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2017,11,15]]},"reference":[{"key":"579_CR1","first-page":"219","volume":"73","author":"P Sainio","year":"1984","unstructured":"Sainio P (1984) Fistula-in-ano in a defined population. Incidence and epidemiological aspects. Ann Chir Gynecol 73:219\u2013224","journal-title":"Ann Chir Gynecol"},{"key":"579_CR2","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1007\/BF01648416","volume":"1","author":"MR Keighley","year":"1986","unstructured":"Keighley MR, Allan RN (1986) Current status and influence of operation on perianal Crohn\u2019s disease. Int J Color Dis 1:104\u2013107","journal-title":"Int J Color Dis"},{"key":"579_CR3","doi-asserted-by":"crossref","first-page":"3806","DOI":"10.3748\/wjg.v18.i29.3806","volume":"18","author":"L Beaugerie","year":"2012","unstructured":"Beaugerie L, Sokol H (2012) Clinical, serological and genetic predictors of inflammatory bowel disease course. World J Gastroenterol 18:3806\u20133813","journal-title":"World J Gastroenterol"},{"key":"579_CR4","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1111\/j.1572-0241.2005.40980.x","volume":"100","author":"DB Sachar","year":"2005","unstructured":"Sachar DB, Bodian CA, Goldstein ES, Present DH, Bayless TM, Picco M et al (2005) Is perianal Crohn\u2019s disease associated with intestinal fistulization? Am J Gastroenterol 100:1547\u20131549","journal-title":"Am J Gastroenterol"},{"issue":"Suppl A","key":"579_CR5","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1155\/2005\/269076","volume":"19","author":"MS Silverberg","year":"2005","unstructured":"Silverberg MS, Satsangi J, Ahmad T, Arnott ID, Bernstein CN, Brant SR et al (2005) Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: report of a working party of the 2005 Montreal World Congress of Gastroenterology. Can J Gastroenterol 19(Suppl A):5\u201336","journal-title":"Can J Gastroenterol"},{"key":"579_CR6","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1002\/ibd.21026","volume":"15","author":"PJ Tozer","year":"2009","unstructured":"Tozer PJ, Whelan K, Phillips RKS, Hart AL (2009) Etiology of perianal Crohn\u2019s disease: role of genetic, microbiological, and immunological factors. Inflamm Bowel Dis 15:1591\u20131598","journal-title":"Inflamm Bowel Dis"},{"key":"579_CR7","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1111\/j.1365-2036.2010.04486.x","volume":"33","author":"PJ Tozer","year":"2011","unstructured":"Tozer PJ, Burling D, Gupta A, Phillips RKS, Hart AL (2011) Review article: medical, surgical and radiological management of perianal Crohn\u2019s fistulas. Aliment Pharmacol Ther 33:5\u201322","journal-title":"Aliment Pharmacol Ther"},{"key":"579_CR8","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1007\/s00261-007-9309-y","volume":"33","author":"V Sahni","year":"2008","unstructured":"Sahni V, Ahmad R (2008) Which method is best for imaging of perianal fistula? Abdom Imaging 33:26\u201330","journal-title":"Abdom Imaging"},{"key":"579_CR9","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1097\/DCR.0b013e318249d26c","volume":"5","author":"MHR Siddiqui","year":"2012","unstructured":"Siddiqui MHR, Ashrafian H, Tozer P, Daulatzai N, Burling D, Hart A et al (2012) A Diagnostic accuracy meta-analysis of endoanal ultrasound and MRI for perianal fistula assessment. Dis Colon Rectum 5:576\u2013585","journal-title":"Dis Colon Rectum"},{"key":"579_CR10","doi-asserted-by":"crossref","first-page":"2367","DOI":"10.7863\/ultra.15.09043","volume":"35","author":"R Bor","year":"2016","unstructured":"Bor R, Farkas K, B\u00e0lint A, Sz\u00fccs M, \u00c1brah\u00e1m S, Milassin \u00c1 et al (2016) Prospective comparison of magnetic resonance imaging, transrectal and transperineal sonography, and surgical findings in complicated perianal Crohn's disease. J Ultrasound Med 35:2367\u20132372","journal-title":"J Ultrasound Med"},{"key":"579_CR11","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S1873-9946(10)00005-X","volume":"4","author":"G Assche Van","year":"2010","unstructured":"Van Assche G, Dignass A, Panes J, Beaugerie L, Karagiannis J, Allez M et al (2010) The second European evidence-based consensus on the diagnosis and management of Crohn\u2019s disease: special situations. J Crohns Colitis 4:3\u2013101","journal-title":"J Crohns Colitis"},{"key":"579_CR12","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1016\/j.crohns.2013.02.020","volume":"7","author":"J Pan\u00e9s","year":"2013","unstructured":"Pan\u00e9s J, Bouhnik Y, Reinisch W, Stoker J, Taylor SA, Baumgart DC et al (2013) Imaging techniques for assessment of inflammatory bowel disease: joint ECCO and ESGAR evidence-based consensus guidelines. J Crohns Colitis 7:556\u2013585","journal-title":"J Crohns Colitis"},{"key":"579_CR13","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1136\/gutjnl-2013-306709","volume":"63","author":"KB Gecse","year":"2014","unstructured":"Gecse KB, Bemelman W, Kamm MA, Stoker J, Khanna R, Ng SC et al (2014) A global consensus on the diagnosis and multidisciplinary treatment of perianal fistulising Crohn's disease. Gut 63:1381\u20131392","journal-title":"Gut"},{"key":"579_CR14","doi-asserted-by":"crossref","first-page":"O119","DOI":"10.1111\/codi.13286","volume":"18","author":"EJ Groof de","year":"2016","unstructured":"de Groof EJ, Cabral VN, Buskens CJ, Morton DG, Hahnloser D, Bemelman WA et al (2016) Systematic review of evidence and consensus on perianal f\u00edstula: an analysis of national and international guidelines. Color Dis 18:O119\u2013O134","journal-title":"Color Dis"},{"key":"579_CR15","doi-asserted-by":"crossref","first-page":"135","DOI":"10.2214\/ajr.183.1.1830135","volume":"183","author":"GN Buchanan","year":"2004","unstructured":"Buchanan GN, Halligan S, Taylor S, Williams A, Cohen R, Bartram C (2004) MRI of fistula in ano: inter- and intraobserver agreement and effects of directed education. AJR Am J Roentgenol 183:135\u2013140","journal-title":"AJR Am J Roentgenol"},{"key":"579_CR16","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1007\/s00261-007-9188-2","volume":"32","author":"E Szurowska","year":"2007","unstructured":"Szurowska E, Wypych J, Izycka-Swieszewska E (2007) Perianal fistulas in Crohn's disease: MRI diagnosis and surgical planning. Abdom Imaging 32:705\u2013718","journal-title":"Abdom Imaging"},{"key":"579_CR17","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1007\/s13244-010-0022-y","volume":"1","author":"MR Torkzad","year":"2010","unstructured":"Torkzad MR, Karlbom U (2010) MRI for assessment of anal fistula. Insights Imaging 1:62\u201371","journal-title":"Insights Imaging"},{"key":"579_CR18","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1148\/radiographics.20.3.g00mc15623","volume":"20","author":"J Morris","year":"2000","unstructured":"Morris J, Spencer JA, Ambrose NS (2000) MR imaging classification of perianal fistulas and its implications for patient management. Radiographics 20:623\u2013635","journal-title":"Radiographics"},{"key":"579_CR19","doi-asserted-by":"crossref","first-page":"1508","DOI":"10.1016\/j.gastro.2003.08.025","volume":"125","author":"WJ Sandborn","year":"2003","unstructured":"Sandborn WJ, Fazio VW, Feagan BG, Hanauer SB (2003) AGA technical review on perianal Crohn\u2019s disease. Gastroenterology 125:1508\u20131530","journal-title":"Gastroenterology"},{"key":"579_CR20","doi-asserted-by":"crossref","first-page":"963","DOI":"10.3748\/wjg.v17.i8.963","volume":"17","author":"Y-F Zhu","year":"2011","unstructured":"Zhu Y-F, Tao G-Q, Zhou N, Xiang C (2011) Current treatment of rectovaginal fistula in Crohn\u2019s disease. World J Gastroenterol 17:963\u2013967","journal-title":"World J Gastroenterol"},{"key":"579_CR21","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1148\/radiol.2311021190","volume":"231","author":"S Dwarkasing","year":"2004","unstructured":"Dwarkasing S, Hussain SM, Hop WCJ, Krestin GP (2004) Anovaginal fistulas: evaluation with endoanal MR imaging. Radiology 231:123\u2013128","journal-title":"Radiology"},{"key":"579_CR22","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.2214\/ajr.183.5.1831309","volume":"183","author":"K Horsthuis","year":"2004","unstructured":"Horsthuis K, Stoker J (2004) MRI of perianal Crohn\u2019s disease. AJR Am J Roentgenol 183:1309\u20131315","journal-title":"AJR Am J Roentgenol"},{"key":"579_CR23","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1097\/DCR.0000000000000131","volume":"57","author":"N Griffin","year":"2014","unstructured":"Griffin N, Williams AB, Anderson S, Irwing PM, Sanderson J, Desai N et al (2014) Hidradenitis suppurativa: MRI features in anogenital disease. Dis Colon Rectum 57:762\u2013771","journal-title":"Dis Colon Rectum"},{"key":"579_CR24","doi-asserted-by":"publisher","unstructured":"Monnier L, Dohan A, Amara N, Zagdanski AM, Drame M, Soyer P et al (2017) Anoperineal disease in hidradenitis suppurativa: MR imaging distinction from perianal Crohn's disease. Eur Radiol. \nhttps:\/\/doi.org\/10.1007\/s00330-017-4776-1","DOI":"10.1007\/s00330-017-4776-1"},{"key":"579_CR25","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1002\/ibd.21261","volume":"16","author":"G Bouguen","year":"2010","unstructured":"Bouguen G, Siproudhis L, Bretagne J-F, Bigard M-A, Peyrin-Biroulet L (2010) Nonfistulizing perianal Crohn\u2019s disease: clinical features, epidemiology, and treatment. Inflamm Bowel Dis 16:1431\u20131442","journal-title":"Inflamm Bowel Dis"},{"key":"579_CR26","first-page":"685","volume":"33","author":"H Ogawa","year":"2013","unstructured":"Ogawa H, Aneda S, Shibata C, Miura K, Nagao M, Ohnuma S et al (2013) Adenocarcinoma associated with perianal fistulas in Crohn's disease. Anticancer Res 33:685\u2013690","journal-title":"Anticancer Res"},{"key":"579_CR27","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1097\/00004836-199501000-00008","volume":"20","author":"EJ Irvine","year":"1995","unstructured":"Irvine EJ (1995) Usual therapy improves perianal Crohn's disease as measured by a new disease activity index. Mc Master IBG Group. J Clin Gastroenterol 20:27\u201332","journal-title":"J Clin Gastroenterol"},{"key":"579_CR28","doi-asserted-by":"crossref","first-page":"1398","DOI":"10.1056\/NEJM199905063401804","volume":"340","author":"D Present","year":"1999","unstructured":"Present D, Rutgeerts P (1999) Infliximab for the treatment of fistulas in patients with Crohn\u2019s disease. N Engl J Med 340:1398\u20131405","journal-title":"N Engl J Med"},{"key":"579_CR29","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1046\/j.1365-2036.2003.01427.x","volume":"17","author":"S Bell","year":"2003","unstructured":"Bell S, Halligan S, Windsor A (2003) Response of fistulating Crohn\u2019s disease to infliximab treatment assessed by magnetic resonance imaging. Aliment Pharmacol Ther 17:387\u2013393","journal-title":"Aliment Pharmacol Ther"},{"key":"579_CR30","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1046\/j.1572-0241.2003.04009.x","volume":"99","author":"I Rasul","year":"2004","unstructured":"Rasul I, Wilson SR, MacRae H, Irwin S, Greenberg GR (2004) Clinical and radiological responses after infliximab treatment for perianal fistulizing Crohn\u2019s disease. Am J Gastroenterol 99:82\u201388","journal-title":"Am J Gastroenterol"},{"key":"579_CR31","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/S0002-9270(02)05909-9","volume":"98","author":"G Assche Van","year":"2003","unstructured":"Van Assche G, Vanbeckevoort D, Bielen D, Coremans G, Aerden I, Noman M et al (2003) Magnetic resonance imaging of the effects of infliximab on perianal fistulizing Crohn\u2019s disease. Am J Gastroenterol 98:332\u2013339","journal-title":"Am J Gastroenterol"},{"key":"579_CR32","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.cgh.2010.10.022","volume":"9","author":"K Karmiris","year":"2011","unstructured":"Karmiris K, Bielen D, Vanbeckevoort D, Vermeire S, Coremans G, Rutgeerts P et al (2011) Long-term monitoring of infliximab therapy for perianal fistulizing Crohn\u2019s disease by using magnetic resonance imaging. Clin Gastroenterol Hepatol 9:130\u2013136","journal-title":"Clin Gastroenterol Hepatol"},{"key":"579_CR33","doi-asserted-by":"crossref","first-page":"2973","DOI":"10.1038\/ajg.2009.509","volume":"104","author":"SC Ng","year":"2009","unstructured":"Ng SC, Plamondon S, Gupta A, Burling D, Swatton A, Vaizey CJ et al (2009) Prospective evaluation of anti-tumor necrosis factor therapy guided by magnetic resonance imaging for Crohn\u2019s perineal fistulas. Am J Gastroenterol 104:2973\u20132986","journal-title":"Am J Gastroenterol"},{"key":"579_CR34","doi-asserted-by":"crossref","first-page":"1751","DOI":"10.1002\/ibd.21568","volume":"17","author":"C Savoye-Collet","year":"2011","unstructured":"Savoye-Collet C, Savoye G, Koning E, Dacher JN, Lerebours E (2011) Fistulizing perianal Crohn\u2019s disease: Contrast-enhanced magnetic resonance imaging assessment at 1 year on maintenance anti-TNF-alpha therapy. Inflamm Bowel Dis 17:1751\u20131758","journal-title":"Inflamm Bowel Dis"},{"key":"579_CR35","doi-asserted-by":"crossref","unstructured":"Hortshuis K, Ziech MLW, Bipat S, Spijkerboer AM, de Bruine-Dobben AC, Hommes DW et al (2011) Evaluation of an MRI-based score of disease activity in perianal fistulizing Crohn\u2019s disease. Clin Imaging 35:360\u2013365","DOI":"10.1016\/j.clinimag.2010.09.003"},{"key":"579_CR36","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1002\/jmri.21934","volume":"30","author":"M Hori","year":"2009","unstructured":"Hori M, Oto A, Orrin S, Suzuki K, Baron RL (2009) Diffusion-weighted MRI: a new tool for the diagnosis of fistula in ano. J Magn Reson Imaging 30:1021\u20131026","journal-title":"J Magn Reson Imaging"},{"key":"579_CR37","doi-asserted-by":"crossref","first-page":"2906","DOI":"10.1007\/s00330-014-3302-y","volume":"24","author":"A Dohan","year":"2014","unstructured":"Dohan A, Eveno C, Oprea R, Pautrat K, Plac\u00e9 V, Pocard M et al (2014) Diffusion-weighted MR imaging for the diagnosis of abscess complicating fistula-in-ano: preliminary experience. Eur Radiol 24:2906\u20132915","journal-title":"Eur Radiol"},{"key":"579_CR38","doi-asserted-by":"crossref","first-page":"2049","DOI":"10.1016\/j.ejrad.2011.06.052","volume":"81","author":"T Yoshizako","year":"2011","unstructured":"Yoshizako T, Wada A, Takahara T, Kwee TC, Nakamura M, Uchida K et al (2011) Diffusion-weighted MRI for evaluating perianal fistula activity: Feasibility study. Eur J Radiol 81:2049\u20132053","journal-title":"Eur J Radiol"},{"key":"579_CR39","doi-asserted-by":"publisher","unstructured":"Gallego JC, Echarri A, Porta A, Fern\u00e1ndez-P\u00e9rez C. Role of diffusion-weighted MRI in the evaluation of perianal Crohn's disease. In: Final Programme ESGAR 2012, Edimburg: SE-012, p 95. \nhttp:\/\/posters.webges.com\/e-Poster\/poster.php?id=47119&from=home\n\n. Access 15 May 2017. \nhttps:\/\/doi.org\/10.5444\/esgar2012\/SE-012","DOI":"10.5444\/esgar2012\/SE-012"},{"key":"579_CR40","doi-asserted-by":"crossref","first-page":"e29084","DOI":"10.5812\/iranjradiol.29084","volume":"12","author":"S Bakan","year":"2015","unstructured":"Bakan S, Olgun DC, Kandemirli SG, Tutar O, Samaci C, Dikici S et al (2015) Perianal fistula with and without abscess: assessment of fistula activity using diffusion-weighted magnetic resonance imaging. Iran J Radiol 12:e29084","journal-title":"Iran J Radiol"},{"key":"579_CR41","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1002\/(SICI)1522-2586(199909)10:3<223::AID-JMRI2>3.0.CO;2-S","volume":"10","author":"PS Tofts","year":"1999","unstructured":"Tofts PS, Brix G, Buckley DL, Evelhoch JL, Henderson E, Knopp MV et al (1999) Estimating kinetic parameters for dynamic contrast-enhanced T(1)-weighted MRI of a diffusable tracer: standardized quantities and symbols. J Magn Reson Imaging 10:223\u2013232","journal-title":"J Magn Reson Imaging"},{"key":"579_CR42","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1148\/radiol.2512072128","volume":"251","author":"K Horsthuis","year":"2009","unstructured":"Horsthuis K, Lavini C, Bipat S, Stokkers P, Stoker J (2009) Perianal Crohn disease: evaluation of dynamic contrast-enhanced MR imaging as an indicator of disease activity. Radiology 251:380\u2013387","journal-title":"Radiology"},{"key":"579_CR43","doi-asserted-by":"crossref","first-page":"W170","DOI":"10.2214\/AJR.11.8276","volume":"200","author":"MLW Ziech","year":"2013","unstructured":"Ziech MLW, Lavini C, Bipat S, Ponsioen CY, Spijkerboer AM, Stokkers PCF et al (2013) Dynamic contrast-enhanced MRI in determining disease activity in perianal fistulizing crohn disease: a pilot study. AJR Am J Roentgenol 200:W170\u2013W177","journal-title":"AJR Am J Roentgenol"},{"key":"579_CR44","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1007\/s00330-016-4350-2","volume":"27","author":"C Pinson","year":"2017","unstructured":"Pinson C, Dolores M, Cruypeninck Y, Koning E, Dacher JN, Savoye G et al (2017) Magnetization transfer ratio for the assessment of perianal activity in Crohn's disease. Eur Radiol 27:80\u201387","journal-title":"Eur Radiol"}],"container-title":["Insights into Imaging"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s13244-017-0579-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s13244-017-0579-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s13244-017-0579-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,2,23]],"date-time":"2018-02-23T19:02:25Z","timestamp":1519412545000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s13244-017-0579-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11,15]]},"references-count":44,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,2]]}},"alternative-id":["579"],"URL":"https:\/\/doi.org\/10.1007\/s13244-017-0579-9","relation":{},"ISSN":["1869-4101"],"issn-type":[{"value":"1869-4101","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,11,15]]}}}