{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T22:07:15Z","timestamp":1767650835292,"version":"3.37.3"},"reference-count":41,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2023,1,20]],"date-time":"2023-01-20T00:00:00Z","timestamp":1674172800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,1,20]],"date-time":"2023-01-20T00:00:00Z","timestamp":1674172800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001809","name":"Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81070308"],"award-info":[{"award-number":["81070308"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"\u201cTechnology Bureau Project\u201d Foundation of Nanjing","award":["201503004"],"award-info":[{"award-number":["201503004"]}]},{"name":"the \u201c333 project\u201d Foundation of Jiang Su","award":["BRA2017180"],"award-info":[{"award-number":["BRA2017180"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Genes Genom"],"published-print":{"date-parts":[[2023,5]]},"DOI":"10.1007\/s13258-022-01347-5","type":"journal-article","created":{"date-parts":[[2023,1,20]],"date-time":"2023-01-20T08:35:46Z","timestamp":1674203746000},"page":"673-680","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Correlation analysis and prognostic value of miR-29a-3p expression and CYP2C19 genotypes in exfoliated cells from tongue coating of patients with gastroesophageal reflux disease"],"prefix":"10.1007","volume":"45","author":[{"given":"Aiqing","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenjuan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lingyun","family":"Niu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liping","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liuqing","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xueliang","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,1,20]]},"reference":[{"key":"1347_CR1","doi-asserted-by":"publisher","first-page":"e0245401","DOI":"10.1371\/journal.pone.0245401","volume":"16","author":"A Arevalo-Galvis","year":"2021","unstructured":"Arevalo-Galvis A, Otero-Regino WA, Ovalle-Celis GN, Rodriguez-Gomez ER, Trespalacios-Rangel AA (2021) Prevalence of CYP2C19 polymorphism in Bogota, Colombia: the first report of allele *17. PLoS One 16:e0245401. https:\/\/doi.org\/10.1371\/journal.pone.0245401","journal-title":"PLoS One"},{"key":"1347_CR2","doi-asserted-by":"publisher","unstructured":"Bradshaw NJ, Ukkola-Vuoti L, Pankakoski M, Zheutlin AB, Ortega-Alonso A, Torniainen-Holm M, Sinha V, Therman S, Paunio T, Suvisaari J et al (2017) The NDE1 genomic locus can affect treatment of psychiatric illness through gene expression changes related to microRNA-484. Open Biol 7. https:\/\/doi.org\/10.1098\/rsob.170153","DOI":"10.1098\/rsob.170153"},{"key":"1347_CR3","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1097\/SGA.0000000000000359","volume":"42","author":"J Chen","year":"2019","unstructured":"Chen J, Brady P (2019) Gastroesophageal reflux disease: pathophysiology, diagnosis, and treatment. Gastroenterol Nurs 42:20\u201328. https:\/\/doi.org\/10.1097\/SGA.0000000000000359","journal-title":"Gastroenterol Nurs"},{"key":"1347_CR4","doi-asserted-by":"publisher","first-page":"6536","DOI":"10.2174\/0929867327666200425214906","volume":"27","author":"YH Chen","year":"2020","unstructured":"Chen YH, Wang H (2020) The Association between Depression and gastroesophageal reflux based on phylogenetic analysis of miRNA biomarkers. Curr Med Chem 27:6536\u20136547. https:\/\/doi.org\/10.2174\/0929867327666200425214906","journal-title":"Curr Med Chem"},{"key":"1347_CR5","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1111\/cts.12589","volume":"12","author":"EJ Cicali","year":"2019","unstructured":"Cicali EJ, Blake K, Gong Y, Mougey EB, Al-Atrash H, Chambers N, Denham J, Evans J, George DE, Gomez R et al (2019) Novel implementation of genotype-guided Proton pump inhibitor medication therapy in children: a pilot, Randomized, Multisite Pragmatic Trial. Clin Transl Sci 12:172\u2013179. https:\/\/doi.org\/10.1111\/cts.12589","journal-title":"Clin Transl Sci"},{"key":"1347_CR6","doi-asserted-by":"publisher","first-page":"e00125","DOI":"10.14309\/ctg.0000000000000125","volume":"11","author":"MP Craig","year":"2020","unstructured":"Craig MP, Rajakaruna S, Paliy O, Sajjad M, Madhavan S, Reddy N, Zhang J, Bottomley M, Agrawal S, Kadakia MP (2020) Differential MicroRNA Signatures in the pathogenesis of Barrett\u2019s Esophagus. Clin Transl Gastroenterol 11:e00125. https:\/\/doi.org\/10.14309\/ctg.0000000000000125","journal-title":"Clin Transl Gastroenterol"},{"key":"1347_CR7","doi-asserted-by":"publisher","first-page":"3065","DOI":"10.1007\/s11695-021-05347-4","volume":"31","author":"A Dalboh","year":"2021","unstructured":"Dalboh A, Al-Shehri DM, Abd El Maksoud WM, Abbas KS, Alqahtani AJ, Al-Malki AQ, Al-Shahrani KA (2021) Impact of laparoscopic sleeve gastrectomy on gastroesophageal reflux disease and risk factors Associated with its occurrence based upon quality of life. Obes Surg 31:3065\u20133074. https:\/\/doi.org\/10.1007\/s11695-021-05347-4","journal-title":"Obes Surg"},{"key":"1347_CR8","doi-asserted-by":"publisher","first-page":"913","DOI":"10.2165\/00003088-200241120-00002","volume":"41","author":"Z Desta","year":"2002","unstructured":"Desta Z, Zhao X, Shin JG, Flockhart DA (2002) Clinical significance of the cytochrome P450 2C19 genetic polymorphism. Clin Pharmacokinet 41:913\u2013958. https:\/\/doi.org\/10.2165\/00003088-200241120-00002","journal-title":"Clin Pharmacokinet"},{"key":"1347_CR9","doi-asserted-by":"publisher","first-page":"2307","DOI":"10.1007\/s10620-008-0413-9","volume":"53","author":"H El-Serag","year":"2008","unstructured":"El-Serag H (2008) The association between obesity and GERD: a review of the epidemiological evidence. Dig Dis Sci 53:2307\u20132312. https:\/\/doi.org\/10.1007\/s10620-008-0413-9","journal-title":"Dig Dis Sci"},{"key":"1347_CR10","doi-asserted-by":"publisher","first-page":"7653","DOI":"10.3748\/wjg.v23.i43.7653","volume":"23","author":"M Fassan","year":"2017","unstructured":"Fassan M, Facchin S, Munari G, Fanelli GN, Lorenzon G, Savarino E (2017) Noncoding RNAs as drivers of the phenotypic plasticity of oesophageal mucosa. World J Gastroenterol 23:7653\u20137656. https:\/\/doi.org\/10.3748\/wjg.v23.i43.7653","journal-title":"World J Gastroenterol"},{"key":"1347_CR11","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1007\/BF03262211","volume":"16","author":"T Furuta","year":"2012","unstructured":"Furuta T, Sugimoto M, Shirai N (2012) Individualized therapy for gastroesophageal reflux disease: potential impact of pharmacogenetic testing based on CYP2C19. Mol Diagn Ther 16:223\u2013234. https:\/\/doi.org\/10.1007\/BF03262211","journal-title":"Mol Diagn Ther"},{"key":"1347_CR13","doi-asserted-by":"publisher","first-page":"1351","DOI":"10.1136\/gutjnl-2017-314722","volume":"67","author":"CP Gyawali","year":"2018","unstructured":"Gyawali CP, Kahrilas PJ, Savarino E, Zerbib F, Mion F, Smout A, Vaezi M, Sifrim D, Fox MR, Vela MF et al (2018) Modern diagnosis of GERD: the Lyon Consensus. Gut 67:1351\u20131362. https:\/\/doi.org\/10.1136\/gutjnl-2017-314722","journal-title":"Gut"},{"key":"1347_CR14","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1136\/gutjnl-2014-307049","volume":"64","author":"JO Hayat","year":"2015","unstructured":"Hayat JO, Gabieta-Somnez S, Yazaki E, Kang JY, Woodcock A, Dettmar P, Mabary J, Knowles CH, Sifrim D (2015) Pepsin in saliva for the diagnosis of gastro-oesophageal reflux disease. Gut 64:373\u2013380. https:\/\/doi.org\/10.1136\/gutjnl-2014-307049","journal-title":"Gut"},{"key":"1347_CR15","doi-asserted-by":"publisher","first-page":"716","DOI":"10.1111\/jgh.13233","volume":"31","author":"H Ichikawa","year":"2016","unstructured":"Ichikawa H, Sugimoto M, Sugimoto K, Andoh A, Furuta T (2016) Rapid metabolizer genotype of CYP2C19 is a risk factor of being refractory to proton pump inhibitor therapy for reflux esophagitis. J Gastroenterol Hepatol 31:716\u2013726. https:\/\/doi.org\/10.1111\/jgh.13233","journal-title":"J Gastroenterol Hepatol"},{"key":"1347_CR16","doi-asserted-by":"publisher","first-page":"936","DOI":"10.1038\/srep00936","volume":"2","author":"B Jiang","year":"2012","unstructured":"Jiang B, Liang X, Chen Y, Ma T, Liu L, Li J, Jiang R, Chen T, Zhang X, Li S (2012) Integrating next-generation sequencing and traditional tongue diagnosis to determine tongue coating microbiome. Sci Rep 2:936. https:\/\/doi.org\/10.1038\/srep00936","journal-title":"Sci Rep"},{"key":"1347_CR17","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1006\/taap.2001.9294","volume":"177","author":"WA Kappers","year":"2001","unstructured":"Kappers WA, Edwards RJ, Murray S, Boobis AR (2001) Diazinon is activated by CYP2C19 in human liver. Toxicol Appl Pharmacol 177:68\u201376. https:\/\/doi.org\/10.1006\/taap.2001.9294","journal-title":"Toxicol Appl Pharmacol"},{"key":"1347_CR18","doi-asserted-by":"publisher","first-page":"965","DOI":"10.1046\/j.1365-2036.2003.01539.x","volume":"17","author":"M Kawamura","year":"2003","unstructured":"Kawamura M, Ohara S, Koike T, Iijima K, Suzuki J, Kayaba S, Noguchi K, Hamada S, Noguchi M, Shimosegawa T et al (2003) The effects of lansoprazole on erosive reflux oesophagitis are influenced by CYP2C19 polymorphism. Aliment Pharmacol Ther 17:965\u2013973. https:\/\/doi.org\/10.1046\/j.1365-2036.2003.01539.x","journal-title":"Aliment Pharmacol Ther"},{"key":"1347_CR19","doi-asserted-by":"publisher","first-page":"2060","DOI":"10.3748\/wjg.v23.i11.2060","volume":"23","author":"F Kawara","year":"2017","unstructured":"Kawara F, Fujita T, Morita Y, Uda A, Masuda A, Saito M, Ooi M, Ishida T, Kondo Y, Yoshida S et al (2017) Factors associated with residual gastroesophageal reflux disease symptoms in patients receiving proton pump inhibitor maintenance therapy. World J Gastroenterol 23:2060\u20132067. https:\/\/doi.org\/10.3748\/wjg.v23.i11.2060","journal-title":"World J Gastroenterol"},{"key":"1347_CR20","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1016\/j.pop.2017.07.001","volume":"44","author":"R Kellerman","year":"2017","unstructured":"Kellerman R, Kintanar T (2017) Gastroesophageal reflux disease. Prim Care 44:561\u2013573. https:\/\/doi.org\/10.1016\/j.pop.2017.07.001","journal-title":"Prim Care"},{"key":"1347_CR21","doi-asserted-by":"publisher","first-page":"79","DOI":"10.5230\/jgc.2013.13.2.79","volume":"13","author":"JJ Kim","year":"2013","unstructured":"Kim JJ (2013) Upper gastrointestinal cancer and reflux disease. J Gastric Cancer 13:79\u201385. https:\/\/doi.org\/10.5230\/jgc.2013.13.2.79","journal-title":"J Gastric Cancer"},{"key":"1347_CR22","doi-asserted-by":"publisher","first-page":"113725","DOI":"10.1016\/j.bcp.2019.113725","volume":"171","author":"N Kugler","year":"2020","unstructured":"Kugler N, Klein K, Zanger UM (2020) MiR-155 and other microRNAs downregulate drug metabolizing cytochromes P450 in inflammation. Biochem Pharmacol 171:113725. https:\/\/doi.org\/10.1016\/j.bcp.2019.113725","journal-title":"Biochem Pharmacol"},{"key":"1347_CR23","doi-asserted-by":"publisher","first-page":"1039","DOI":"10.1007\/s10620-015-3959-3","volume":"61","author":"R Mallick","year":"2016","unstructured":"Mallick R, Patnaik SK, Wani S, Bansal A (2016) A systematic review of esophageal MicroRNA markers for diagnosis and monitoring of Barrett\u2019s Esophagus. Dig Dis Sci 61:1039\u20131050. https:\/\/doi.org\/10.1007\/s10620-015-3959-3","journal-title":"Dig Dis Sci"},{"key":"1347_CR24","doi-asserted-by":"publisher","first-page":"1045","DOI":"10.1016\/j.bcp.2009.11.015","volume":"79","author":"T Mohri","year":"2010","unstructured":"Mohri T, Nakajima M, Fukami T, Takamiya M, Aoki Y, Yokoi T (2010) Human CYP2E1 is regulated by miR-378. Biochem Pharmacol 79:1045\u20131052. https:\/\/doi.org\/10.1016\/j.bcp.2009.11.015","journal-title":"Biochem Pharmacol"},{"key":"1347_CR25","doi-asserted-by":"publisher","unstructured":"Ness-Jensen E, Hveem K, El-Serag H, Lagergren J (2016) Lifestyle Intervention in Gastroesophageal Reflux Disease. Clin Gastroenterol Hepatol. 14: 175\u2013182 e171-173. https:\/\/doi.org\/10.1016\/j.cgh.2015.04.176","DOI":"10.1016\/j.cgh.2015.04.176"},{"key":"1347_CR26","doi-asserted-by":"publisher","first-page":"S1594","DOI":"10.21037\/jtd.2019.06.42","volume":"11","author":"C Newberry","year":"2019","unstructured":"Newberry C, Lynch K (2019) The role of diet in the development and management of gastroesophageal reflux disease: why we feel the burn. J Thorac Dis 11:S1594\u2013S1601. https:\/\/doi.org\/10.21037\/jtd.2019.06.42","journal-title":"J Thorac Dis"},{"key":"1347_CR27","doi-asserted-by":"publisher","DOI":"10.1007\/s11695-022-05955-8","author":"S Olmi","year":"2022","unstructured":"Olmi S, Cesana G, Gambioli A, Bonaldi M, Ferrari D, Uccelli M, Ciccarese F, Stefano C, Riccardo G, Lorenzo M (2022) Effect of laparoscopic sleeve gastrectomy vs laparoscopic sleeve + Rossetti fundoplication on weight loss and de novo GERD in patients affected by morbid obesity: a randomized clinical study. Obes Surg. https:\/\/doi.org\/10.1007\/s11695-022-05955-8","journal-title":"Obes Surg"},{"key":"1347_CR28","doi-asserted-by":"publisher","first-page":"1037","DOI":"10.1080\/17474124.2021.1890030","volume":"15","author":"AC Ortiz","year":"2021","unstructured":"Ortiz AC, Fideles SOM, Pomini KT, Buchaim RL (2021) Updates in association of gastroesophageal reflux disease and dental erosion: systematic review. Expert Rev Gastroenterol Hepatol 15:1037\u20131046. https:\/\/doi.org\/10.1080\/17474124.2021.1890030","journal-title":"Expert Rev Gastroenterol Hepatol"},{"key":"1347_CR29","doi-asserted-by":"publisher","first-page":"2112","DOI":"10.1124\/dmd.109.027680","volume":"37","author":"YZ Pan","year":"2009","unstructured":"Pan YZ, Gao W, Yu AM (2009) MicroRNAs regulate CYP3A4 expression via direct and indirect targeting. Drug Metab Dispos 37:2112\u20132117. https:\/\/doi.org\/10.1124\/dmd.109.027680","journal-title":"Drug Metab Dispos"},{"key":"1347_CR30","doi-asserted-by":"publisher","first-page":"837","DOI":"10.1097\/00042737-200012080-00002","volume":"12","author":"JE Pandolfino","year":"2000","unstructured":"Pandolfino JE, Kahrilas PJ (2000) Smoking and gastro-oesophageal reflux disease. Eur J Gastroenterol Hepatol 12:837\u2013842. https:\/\/doi.org\/10.1097\/00042737-200012080-00002","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"1347_CR31","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1080\/00365529950173609","volume":"34","author":"TK Rantanen","year":"1999","unstructured":"Rantanen TK, Salo JA (1999) Gastroesophageal reflux disease as a cause of death: analysis of fatal cases under conservative treatment. Scand J Gastroenterol 34:229\u2013233. https:\/\/doi.org\/10.1080\/00365529950173609","journal-title":"Scand J Gastroenterol"},{"key":"1347_CR32","doi-asserted-by":"publisher","first-page":"117364","DOI":"10.1016\/j.lfs.2020.117364","volume":"245","author":"AR Sharma","year":"2020","unstructured":"Sharma AR, Vohra M, Shukla V, Guddattu V, Razak Uk A, Shetty R, Umakanth S, Satyamoorthy K, Rai PS (2020) Coding SNPs in hsa-mir-1343-3p and hsa-mir-6783-3p target sites of CYP2C19 modulates clopidogrel response in individuals with cardiovascular diseases. Life Sci 245:117364. https:\/\/doi.org\/10.1016\/j.lfs.2020.117364","journal-title":"Life Sci"},{"key":"1347_CR33","doi-asserted-by":"publisher","first-page":"1139","DOI":"10.1007\/s11695-020-05111-0","volume":"31","author":"FC Silveira","year":"2021","unstructured":"Silveira FC, Poa-Li C, Pergamo M, Gujral A, Kolli S, Fielding GA, Ren-Fielding CJ, Schwack BF (2021) The effect of laparoscopic sleeve gastrectomy on gastroesophageal reflux disease. Obes Surg 31:1139\u20131146. https:\/\/doi.org\/10.1007\/s11695-020-05111-0","journal-title":"Obes Surg"},{"key":"1347_CR34","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1186\/1471-230X-13-4","volume":"13","author":"CM Smith","year":"2013","unstructured":"Smith CM, Michael MZ, Watson DI, Tan G, Astill DS, Hummel R, Hussey DJ (2013) Impact of gastro-oesophageal reflux on microRNA expression, location and function. BMC Gastroenterol 13:4. https:\/\/doi.org\/10.1186\/1471-230X-13-4","journal-title":"BMC Gastroenterol"},{"key":"1347_CR35","doi-asserted-by":"publisher","first-page":"9090","DOI":"10.1158\/0008-5472.CAN-06-1403","volume":"66","author":"Y Tsuchiya","year":"2006","unstructured":"Tsuchiya Y, Nakajima M, Takagi S, Taniya T, Yokoi T (2006) MicroRNA regulates the expression of human cytochrome P450 1B1. Cancer Res 66:9090\u20139098. https:\/\/doi.org\/10.1158\/0008-5472.CAN-06-1403","journal-title":"Cancer Res"},{"key":"1347_CR36","doi-asserted-by":"publisher","unstructured":"Uemura R, Murakami Y, Hashimoto A, Sawada A, Otani K, Taira K, Hosomi S, Nagami Y, Tanaka F, Kamata N et al (2017) Expression of serum exosomal and esophageal MicroRNA in rat reflux esophagitis. Int J Mol Sci 18. https:\/\/doi.org\/10.3390\/ijms18081611","DOI":"10.3390\/ijms18081611"},{"key":"1347_CR37","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1007\/s00228-010-0811-8","volume":"66","author":"RM Ward","year":"2010","unstructured":"Ward RM, Tammara B, Sullivan SE, Stewart DL, Rath N, Meng X, Maguire MK, Comer GM (2010) Single-dose, multiple-dose, and population pharmacokinetics of pantoprazole in neonates and preterm infants with a clinical diagnosis of gastroesophageal reflux disease (GERD). Eur J Clin Pharmacol 66:555\u2013561. https:\/\/doi.org\/10.1007\/s00228-010-0811-8","journal-title":"Eur J Clin Pharmacol"},{"key":"1347_CR38","doi-asserted-by":"publisher","unstructured":"Yan X, Zhu S, Zhang H (2016) miR-203 Expression in Exfoliated Cells of Tongue Coating Represents a Sensitive and Specific Biomarker of Gastroesophageal Reflux Disease. Gastroenterol Res Pract. 2016: 2349453. https:\/\/doi.org\/10.1155\/2016\/2349453","DOI":"10.1155\/2016\/2349453"},{"key":"1347_CR39","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1016\/j.bcp.2015.08.094","volume":"98","author":"D Yu","year":"2015","unstructured":"Yu D, Green B, Tolleson WH, Jin Y, Mei N, Guo Y, Deng H, Pogribny I, Ning B (2015) MicroRNA hsa-miR-29a-3p modulates CYP2C19 in human liver cells. Biochem Pharmacol 98:215\u2013223. https:\/\/doi.org\/10.1016\/j.bcp.2015.08.094","journal-title":"Biochem Pharmacol"},{"key":"1347_CR40","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1093\/toxsci\/kfq296","volume":"118","author":"X Yu","year":"2010","unstructured":"Yu X, Dhakal IB, Beggs M, Edavana VK, Williams S, Zhang X, Mercer K, Ning B, Lang NP, Kadlubar FF et al (2010) Functional genetic variants in the 3\u2019-untranslated region of sulfotransferase isoform 1A1 (SULT1A1) and their effect on enzymatic activity. Toxicol Sci 118:391\u2013403. https:\/\/doi.org\/10.1093\/toxsci\/kfq296","journal-title":"Toxicol Sci"},{"key":"1347_CR41","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/j.pharmthera.2012.12.007","volume":"138","author":"UM Zanger","year":"2013","unstructured":"Zanger UM, Schwab M (2013) Cytochrome P450 enzymes in drug metabolism: regulation of gene expression, enzyme activities, and impact of genetic variation. Pharmacol Ther 138:103\u2013141. https:\/\/doi.org\/10.1016\/j.pharmthera.2012.12.007","journal-title":"Pharmacol Ther"},{"key":"1347_CR42","doi-asserted-by":"publisher","first-page":"120458","DOI":"10.1016\/j.lfs.2022.120458","volume":"298","author":"LF Zhao","year":"2022","unstructured":"Zhao LF, Qi FY, Zhang JG, Pang JR, Ren HM, Shen DD, Zhao LJ, Qi L, Liu HM, Zheng YC (2022) Identification of the upstream regulators of KDM5B in gastric cancer. Life Sci 298:120458. https:\/\/doi.org\/10.1016\/j.lfs.2022.120458","journal-title":"Life Sci"}],"container-title":["Genes &amp; Genomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13258-022-01347-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s13258-022-01347-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13258-022-01347-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,18]],"date-time":"2023-04-18T07:47:41Z","timestamp":1681804061000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s13258-022-01347-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,20]]},"references-count":41,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,5]]}},"alternative-id":["1347"],"URL":"https:\/\/doi.org\/10.1007\/s13258-022-01347-5","relation":{},"ISSN":["1976-9571","2092-9293"],"issn-type":[{"type":"print","value":"1976-9571"},{"type":"electronic","value":"2092-9293"}],"subject":[],"published":{"date-parts":[[2023,1,20]]},"assertion":[{"value":"3 August 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 November 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 January 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"<b>Ethics statement<\/b>.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was in compliance with the code of ethics for human rights mentioned in the 7th revision of the 1975 Declaration of Helsinki (2013) and the protocols were ratified by the Ethics Committee of Shanxi Academy of Medical Sciences, Shanxi Dayi Hospital(YXLL-2017-004). All participants enrolled were informed and provided the signed the consent form.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}]}}