{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T04:18:38Z","timestamp":1774930718116,"version":"3.50.1"},"reference-count":54,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2024,5,22]],"date-time":"2024-05-22T00:00:00Z","timestamp":1716336000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,5,22]],"date-time":"2024-05-22T00:00:00Z","timestamp":1716336000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82301856"],"award-info":[{"award-number":["82301856"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Guangdong Medical Science and Technology Research Fund","award":["B2023145"],"award-info":[{"award-number":["B2023145"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Genes Genom"],"published-print":{"date-parts":[[2024,7]]},"DOI":"10.1007\/s13258-024-01497-8","type":"journal-article","created":{"date-parts":[[2024,5,22]],"date-time":"2024-05-22T15:02:06Z","timestamp":1716390126000},"page":"803-815","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Immune micro-environment analysis and drug screening for ovarian endometriosis"],"prefix":"10.1007","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6096-634X","authenticated-orcid":false,"given":"Qingli","family":"Quan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heng","family":"Gu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yongxia","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meixing","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,5,22]]},"reference":[{"key":"1497_CR1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22105196","author":"D Artemova","year":"2021","unstructured":"Artemova D, Vishnyakova P, Khashchenko E et al (2021) Endometriosis and cancer: exploring the role of macrophages. Int J Mol Sci. https:\/\/doi.org\/10.3390\/ijms22105196","journal-title":"Int J Mol Sci"},{"key":"1497_CR2","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1016\/j.jri.2015.01.003","volume":"109","author":"GM Borrelli","year":"2015","unstructured":"Borrelli GM, Kaufmann AM, Abr\u00e3o MS et al (2015) Addition of MCP-1 and MIP-3\u03b2 to the IL-8 appraisal in peritoneal fluid enhances the probability of identifying women with endometriosis. J Reprod Immunol 109:66\u201373","journal-title":"J Reprod Immunol"},{"key":"1497_CR3","doi-asserted-by":"publisher","first-page":"2458","DOI":"10.1093\/humrep\/den246","volume":"23","author":"O Celik","year":"2008","unstructured":"Celik O, Hascalik S, Elter K et al (2008) Combating endometriosis by blocking proteasome and nuclear factor-kappaB pathways. Hum Reprod 23:2458\u20132465","journal-title":"Hum Reprod"},{"key":"1497_CR4","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1007\/978-1-4939-7493-1_12","volume":"1711","author":"B Chen","year":"2018","unstructured":"Chen B, Khodadoust MS, Liu CL, Newman AM et al (2018) Profifiling tumor infifiltrating immune cells with Cibersort. Methods Mol Biol 1711:243\u2013259","journal-title":"Methods Mol Biol"},{"key":"1497_CR5","doi-asserted-by":"publisher","first-page":"1134663","DOI":"10.3389\/fimmu.2023.1134663","volume":"14","author":"S Chen","year":"2023","unstructured":"Chen S, Liu Y, Zhong Z et al (2023) Peritoneal immune microenvironment of endometriosis: role and therapeutic perspectives. Front Immunol 14:1134663","journal-title":"Front Immunol"},{"key":"1497_CR6","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1016\/S0889-8545(05)70302-8","volume":"24","author":"B Eskenazi","year":"1997","unstructured":"Eskenazi B, Warner ML (1997) Epidemiology of endometriosis. Obstet Gynecol Clin N Am 24:235\u2013258","journal-title":"Obstet Gynecol Clin N Am"},{"key":"1497_CR7","doi-asserted-by":"publisher","first-page":"1255","DOI":"10.1084\/jem.20182015","volume":"216","author":"IZ Fernandez","year":"2019","unstructured":"Fernandez IZ, Baxter RM, Garcia-Perez JE et al (2019) A novel human IL2RB mutation results in T and NK cell-driven immune dysregulation. J Exp Med 216:1255\u20131267","journal-title":"J Exp Med"},{"key":"1497_CR8","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1038\/s41597-020-00623-x","volume":"7","author":"M Gabriel","year":"2020","unstructured":"Gabriel M, Fey V, Heinosalo T et al (2020) A relational database to identify differentially expressed genes in the endometrium and endometriosis lesions. Sci Data 7:284","journal-title":"Sci Data"},{"key":"1497_CR9","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1073\/pnas.0609412103","volume":"104","author":"AV Galkin","year":"2007","unstructured":"Galkin AV, Melnick JS, Kim S et al (2007) Identification of NVP-TAE684, a potent, selective, and efficacious inhibitor of NPM-ALK. Ptoc Natl Acad Sci USA 104:270\u2013275","journal-title":"Ptoc Natl Acad Sci USA"},{"key":"1497_CR10","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0107468","author":"P Geeleher","year":"2014","unstructured":"Geeleher P, Cox N, Huang RS (2014) pRRophetic: an R package for prediction of clinical chemotherapeutic response from tumor gene expression levels. PLoS\u00a0One. https:\/\/doi.org\/10.1371\/journal.pone.0107468","journal-title":"PLoS\u00a0One"},{"key":"1497_CR11","doi-asserted-by":"publisher","first-page":"3573","DOI":"10.1016\/j.cell.2021.04.048","volume":"184","author":"Y Hao","year":"2021","unstructured":"Hao Y, Hao S, Andersen-Nissen E et al (2021) Integrated analysis of multimodal single-cell data. Cell 184:3573-3587.e29","journal-title":"Cell"},{"key":"1497_CR12","doi-asserted-by":"publisher","first-page":"334","DOI":"10.1016\/j.bbrc.2020.02.053","volume":"525","author":"S He","year":"2020","unstructured":"He S, Hu Q, Xu X et al (2020) Advanced glycation end products enhance M1 macrophage polarization by activating the MAPK pathway. Biochem Biophys Res Commun 525:334\u2013340","journal-title":"Biochem Biophys Res Commun"},{"key":"1497_CR13","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/ijms19010092","volume":"19","author":"D Hirayama","year":"2017","unstructured":"Hirayama D, Iida T, Nakase H (2017) The phagocytic function of macrophage-enforcing innate immunity and tissue homeostasis. Int J Mol Sci 19:1\u201314","journal-title":"Int J Mol Sci"},{"key":"1497_CR14","doi-asserted-by":"publisher","DOI":"10.1038\/psp.2013.56","volume":"2","author":"K Ito","year":"2013","unstructured":"Ito K, Murphy D (2013) Application of ggplot2 to pharmacometric graphics. CPT Pharmacomet Syst Pharmacol 2:e79","journal-title":"CPT Pharmacomet Syst Pharmacol"},{"key":"1497_CR15","doi-asserted-by":"publisher","first-page":"42","DOI":"10.7150\/ijms.10076","volume":"12","author":"IC Jeung","year":"2015","unstructured":"Jeung IC, Chung YJ, Chae B et al (2015) Effect of helixor A on natural killer cell activity in endometriosis. Int J Med Sci 12:42\u201347","journal-title":"Int J Med Sci"},{"key":"1497_CR16","doi-asserted-by":"publisher","first-page":"1191","DOI":"10.1016\/j.fertnstert.2017.03.013","volume":"107","author":"H J\u00f8rgensen","year":"2017","unstructured":"J\u00f8rgensen H, Hill AS, Beste MT et al (2017) Peritoneal fluid cytokines related to endometriosis in patients evaluated for infertility. Fertil Steril 107:1191\u201399.e2","journal-title":"Fertil Steril"},{"key":"1497_CR17","doi-asserted-by":"publisher","DOI":"10.1016\/j.cyto.2021.155700","volume":"148","author":"JB Kaushal","year":"2021","unstructured":"Kaushal JB, Shukla V, Sankhwar P et al (2021) Targeted inhibition of TAK1 abrogates TGF\u03b21 non-canonical signaling axis, NF\u03baB\/Smad7 inhibiting human endometriotic cells proliferation and inducing cell death involving autophagy. Cytokine 148:155700","journal-title":"Cytokine"},{"key":"1497_CR18","doi-asserted-by":"publisher","DOI":"10.3390\/cancers14163844","author":"\u0141 Kuncman","year":"2022","unstructured":"Kuncman \u0141, Orzechowska M, Stawiski K et al (2022) The kinetics of fms-related tyrosine kinase 3 ligand (flt-3l) during chemoradiotherapy suggests a potential gain from the earlier initiation of immunotherapy. Cancers (basel). https:\/\/doi.org\/10.3390\/cancers14163844","journal-title":"Cancers (basel)"},{"key":"1497_CR19","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1080\/09513590.2019.1683821","volume":"36","author":"AS Lagan\u00e0","year":"2020","unstructured":"Lagan\u00e0 AS, Salmeri FM, Ban Frange\u017e H et al (2020) Evaluation of M1 and M2 macrophages in ovarian endometriomas from women affected by endometriosis at different stages of the disease. Gynecol Endocrinol 36:441\u2013444","journal-title":"Gynecol Endocrinol"},{"key":"1497_CR20","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1186\/1471-2105-9-559","volume":"9","author":"P Langfelder","year":"2008","unstructured":"Langfelder P, Horvath S (2008) WGCNA: an R package for weighted correlation network analysis. BMC Bioinform 9:559","journal-title":"BMC Bioinform"},{"key":"1497_CR21","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1016\/j.cbi.2016.07.024","volume":"256","author":"S Lee","year":"2016","unstructured":"Lee S, Ku SK, Bae JS (2016) Anti-inflammatory effects of dabrafenib on polyphosphate-mediated vascular disruption. Chem-Biol Interact 256:266\u2013273","journal-title":"Chem-Biol Interact"},{"issue":"7","key":"1497_CR22","doi-asserted-by":"publisher","first-page":"1821","DOI":"10.1007\/s00262-020-02831-1","volume":"70","author":"S Leenen","year":"2021","unstructured":"Leenen S, Hermens M, de Vos van Steenwijk PJ et al (2021) Immunologic factors involved in the malignant transformation of\u00a0endometriosis\u00a0to\u00a0endometriosis-associated\u00a0ovarian\u00a0carcinoma. Cancer Immunol Immun 70(7):1821\u20131829","journal-title":"Cancer Immunol Immun"},{"key":"1497_CR23","doi-asserted-by":"publisher","first-page":"898","DOI":"10.18632\/aging.101786","volume":"11","author":"B Li","year":"2019","unstructured":"Li B, Tan TB, Wang L et al (2019) p38MAPK\/SGK1 signaling regulates macrophage polarization in experimental autoimmune encephalomyelitis. Aging (albany NY) 11:898\u2013907","journal-title":"Aging (albany NY)"},{"key":"1497_CR24","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.707784","volume":"12","author":"Q Li","year":"2021","unstructured":"Li Q, Yuan M, Jiao X et al (2021) M1 macrophage-derived nanovesicles repolarize m2 macrophages for inhibiting the development of endometriosis. Front Immunol 12:707784","journal-title":"Front Immunol"},{"key":"1497_CR25","doi-asserted-by":"publisher","first-page":"252","DOI":"10.1016\/j.jhep.2016.03.016","volume":"65","author":"S Lunemann","year":"2016","unstructured":"Lunemann S, Martrus G, H\u00f6lzemer A et al (2016) Sequence variations in HCV core-derived epitopes alter binding of KIR2DL3 to HLA-C\u221703:04 and modulate NK cell function. J Hepatol 65:252\u2013258","journal-title":"J Hepatol"},{"key":"1497_CR26","first-page":"1349","volume":"41","author":"X Lv","year":"2018","unstructured":"Lv X, Wang D, Ma Y et al (2018) Analysis of the oncogene BRAF mutation and the correlation of the expression of wild-type BRAF and CREB1 in endometriosis. Int J Mol Med 41:1349\u20131356","journal-title":"Int J Mol Med"},{"key":"1497_CR27","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1186\/s13578-021-00637-x","volume":"11","author":"J Ma","year":"2021","unstructured":"Ma J, Zhang L, Zhan H et al (2021) Single-cell transcriptomic analysis of endometriosis provides insights into fibroblast fates and immune cell heterogeneity. Cell Biosci 11:125","journal-title":"Cell Biosci"},{"key":"1497_CR28","doi-asserted-by":"publisher","first-page":"316","DOI":"10.1198\/000313002533","volume":"256","author":"F Michael","year":"2002","unstructured":"Michael F (2002) Corrgrams. Am Statistician 256:316\u2013324. https:\/\/doi.org\/10.1198\/000313002533","journal-title":"Am Statistician"},{"key":"1497_CR29","doi-asserted-by":"publisher","first-page":"108","DOI":"10.3389\/fimmu.2020.00108","volume":"11","author":"JE Miller","year":"2020","unstructured":"Miller JE, Ahn SH, Marks RM et al (2020) IL-17A modulates peritoneal macrophage recruitment and m2 polarization in endometriosis. Front Immunol 11:108","journal-title":"Front Immunol"},{"key":"1497_CR30","doi-asserted-by":"publisher","first-page":"234","DOI":"10.4049\/immunohorizons.2100029","volume":"5","author":"Y Morikawa","year":"2021","unstructured":"Morikawa Y, Murakami M, Kondo H et al (2021) Natural killer cell group 7 sequence in cytotoxic cells optimizes exocytosis of lytic granules essential for the perforin-dependent, but not fas ligand-dependent, cytolytic pathway. Immunohorizons 5:234\u2013245","journal-title":"Immunohorizons"},{"key":"1497_CR31","doi-asserted-by":"publisher","first-page":"2881","DOI":"10.1002\/1521-4141(2002010)32:10<2881::AID-IMMU2881>3.0.CO;2-K","volume":"32","author":"J Pardo","year":"2002","unstructured":"Pardo J, Balkow S, Anel A et al (2002) Granzymes are essential for natural killer cell-mediated and perf-facilitated tumor control. Eur J Immunol 32:2881\u20132887","journal-title":"Eur J Immunol"},{"key":"1497_CR32","doi-asserted-by":"publisher","first-page":"1475","DOI":"10.1093\/humrep\/dew085","volume":"31","author":"J Prescott","year":"2016","unstructured":"Prescott J, Farland LV, Tobias DK et al (2016) A prospective cohort study of endometriosis and subsequent risk of infertility. Hum Reprod 31:1475\u20131482","journal-title":"Hum Reprod"},{"key":"1497_CR33","doi-asserted-by":"publisher","DOI":"10.3390\/ijms221910792","author":"TN Ram\u00edrez-Pavez","year":"2021","unstructured":"Ram\u00edrez-Pavez TN, Mart\u00ednez-Esparza M, Ruiz-Alcaraz AJ et al (2021) The role of peritoneal macrophages in endometriosis. Int J Mol Sci. https:\/\/doi.org\/10.3390\/ijms221910792","journal-title":"Int J Mol Sci"},{"key":"1497_CR34","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1186\/1471-2105-12-77","volume":"12","author":"X Robin","year":"2011","unstructured":"Robin X, Turck N, Hainard A et al (2011) pROC: an open-source package for R and S+ to analyze and compare ROC curves. BMC Bioinform 12:77","journal-title":"BMC Bioinform"},{"key":"1497_CR35","doi-asserted-by":"publisher","first-page":"6425","DOI":"10.1002\/jcp.26429","volume":"233","author":"A Shapouri-Moghaddam","year":"2018","unstructured":"Shapouri-Moghaddam A, Mohammadian S, Vazini H et al (2018) Macrophage plasticity, polarization, and function in health and disease. J Cell Physiol 233:6425\u20136440","journal-title":"J Cell Physiol"},{"key":"1497_CR36","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1186\/s12916-022-02500-3","volume":"20","author":"AJ Shih","year":"2022","unstructured":"Shih AJ, Adelson RP, Vashistha H et al (2022) Single-cell analysis of menstrual endometrial tissues defines phenotypes associated with endometriosis. BMC Med 20:315","journal-title":"BMC Med"},{"key":"1497_CR37","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1002\/eji.201545757","volume":"46","author":"MJ Sim","year":"2016","unstructured":"Sim MJ, Stowell J, Sergeant R et al (2016) KIR2DL3 and KIR2DL1 show similar impact on licensing of human NK cells. Eur J Immunol 46:185\u2013191","journal-title":"Eur J Immunol"},{"key":"1497_CR38","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1016\/j.exphem.2008.10.011","volume":"37","author":"C Stoeckle","year":"2009","unstructured":"Stoeckle C, Gouttefangeas C, Hammer M et al (2009) Cathepsin W expressed exclusively in CD8+ T cells and NK cells, is secreted during target cell killing but is not essential for cytotoxicity in human CTLs. Exp Hematol 37:266\u2013275","journal-title":"Exp Hematol"},{"key":"1497_CR39","doi-asserted-by":"publisher","first-page":"1888","DOI":"10.1016\/j.cell.2019.05.031","volume":"177","author":"T Stuart","year":"2019","unstructured":"Stuart T, Butler A, Hoffman P et al (2019) Comprehensive integration of single-cell data. Cell 177:1888-1902.e21","journal-title":"Cell"},{"key":"1497_CR40","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/S0015-0282(16)59280-2","volume":"48","author":"CH Syrop","year":"1987","unstructured":"Syrop CH, Halme J (1987) Peritoneal fluid environment and infertility. Fertil Steril 48:1\u20139","journal-title":"Fertil Steril"},{"key":"1497_CR41","doi-asserted-by":"publisher","first-page":"1306","DOI":"10.1038\/s41556-022-00961-5","volume":"24","author":"Y Tan","year":"2022","unstructured":"Tan Y, Flynn WF, Sivajothi S et al (2022) Single-cell analysis of endometriosis reveals a coordinated transcriptional programme driving immunotolerance and angiogenesis across eutopic and ectopic tissues. Nat Cell Biol 24:1306\u20131318","journal-title":"Nat Cell Biol"},{"key":"1497_CR42","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1111\/j.1600-0897.2010.00920.x","volume":"65","author":"Y Tao","year":"2011","unstructured":"Tao Y, Zhang Q, Huang W et al (2011) The peritoneal leptin, MCP-1 and TNF-\u03b1 in the pathogenesis of endometriosis-associated infertility. Am J Reprod Immunol 65:403\u2013406","journal-title":"Am J Reprod Immunol"},{"key":"1497_CR43","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1111\/aji.12408","volume":"74","author":"U Thiruchelvam","year":"2015","unstructured":"Thiruchelvam U, Wingfield M, O\u2019Farrelly C (2015) Natural killer cells: key players in endometriosis. Am J Reprod Immunol 74:291\u2013301","journal-title":"Am J Reprod Immunol"},{"key":"1497_CR44","doi-asserted-by":"publisher","first-page":"564","DOI":"10.1093\/humupd\/dmz018","volume":"25","author":"J Vallv\u00e9-Juanico","year":"2019","unstructured":"Vallv\u00e9-Juanico J, Houshdaran S, Giudice LC (2019) The endometrial immune environment of women with endometriosis. Hum Reprod Update 25:564\u2013591","journal-title":"Hum Reprod Update"},{"key":"1497_CR45","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1016\/j.jri.2012.11.003","volume":"97","author":"DV Veljkovic","year":"2013","unstructured":"Veljkovic DV, Dominovic M, Gulic T et al (2013) Granulysin expression and the interplay of granulysin and perforin at the maternal-fetal interface. J Reprod Immunol 97:186\u2013196","journal-title":"J Reprod Immunol"},{"key":"1497_CR46","doi-asserted-by":"publisher","first-page":"3869","DOI":"10.1007\/s00520-019-4654-2","volume":"27","author":"J Vera","year":"2019","unstructured":"Vera J, Paludo J, Kottschade L et al (2019) Case series of dabrafenib-trametinib-induced pyrexia successfully treated with colchicine. Support Care Cancer 27:3869\u20133875","journal-title":"Support Care Cancer"},{"key":"1497_CR47","doi-asserted-by":"publisher","first-page":"113","DOI":"10.2174\/1574892815666200401113805","volume":"15","author":"PA Vora","year":"2020","unstructured":"Vora PA, Patel R, Dharamsi A (2020) Bortezomib - first therapeutic proteasome inhibitor for cancer therapy: a review of patent literature. Recent Pat Anticancer 15:113\u2013131","journal-title":"Recent Pat Anticancer"},{"key":"1497_CR48","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.711231","volume":"12","author":"L Wang","year":"2021","unstructured":"Wang L, Li L, Li Y et al (2021) A history of endometriosis is associated with decreased peripheral nk cytotoxicity and increased infiltration of uterine cd68+ macrophages. Front Immunol 12:711231","journal-title":"Front Immunol"},{"key":"1497_CR49","doi-asserted-by":"publisher","first-page":"2172","DOI":"10.4049\/jimmunol.167.4.2172","volume":"167","author":"T Wex","year":"2001","unstructured":"Wex T, B\u00fchling F, Wex H et al (2001) Human cathepsin W, a cysteine protease predominantly expressed in NK cells, is mainly localized in the endoplasmic reticulum. J Immunol 167:2172\u20132178","journal-title":"J Immunol"},{"key":"1497_CR50","volume":"2","author":"T Wu","year":"2021","unstructured":"Wu T, Hu E, Xu S et al (2021) clusterProfiler 4.0: a universal enrichment tool for interpreting omics data. Innovation (n y) 2:100141","journal-title":"Innovation (n y)"},{"key":"1497_CR51","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1089\/omi.2011.0118","volume":"16","author":"G Yu","year":"2012","unstructured":"Yu G, Wang LG, Han Y et al (2012) clusterProfiler: an R package for comparing biological themes among gene clusters. OMICS 16:284\u2013287","journal-title":"OMICS"},{"key":"1497_CR52","doi-asserted-by":"publisher","first-page":"1154","DOI":"10.1038\/modpathol.2013.245","volume":"27","author":"Z Yuan","year":"2014","unstructured":"Yuan Z, Wang L, Wang Y et al (2014) Tubal origin of ovarian endometriosis. Mod Pathol 27:1154\u20131162","journal-title":"Mod Pathol"},{"key":"1497_CR53","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1080\/09513590.2022.2109145","volume":"38","author":"V Zajec","year":"2022","unstructured":"Zajec V, Miku\u0161 M, Vitale SG et al (2022) Current status and challenges of drug development for hormonal treatment of endometriosis: a systematic review of randomized control trials. Gynecol Endocrinol 38:713\u2013720","journal-title":"Gynecol Endocrinol"},{"key":"1497_CR54","doi-asserted-by":"publisher","first-page":"1244","DOI":"10.1056\/NEJMra1810764","volume":"382","author":"KT Zondervan","year":"2020","unstructured":"Zondervan KT, Becker CM, Missmer SA (2020) Endometriosis. N Engl JMed 382:1244\u20131256","journal-title":"N Engl JMed"}],"container-title":["Genes &amp; Genomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13258-024-01497-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s13258-024-01497-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13258-024-01497-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,26]],"date-time":"2024-06-26T06:25:33Z","timestamp":1719383133000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s13258-024-01497-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,22]]},"references-count":54,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["1497"],"URL":"https:\/\/doi.org\/10.1007\/s13258-024-01497-8","relation":{},"ISSN":["1976-9571","2092-9293"],"issn-type":[{"value":"1976-9571","type":"print"},{"value":"2092-9293","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,22]]},"assertion":[{"value":"28 August 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 January 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 May 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All the authors certify that there is no potential conflicts of interest with any financial or organization regarding manuscript.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}