{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T17:55:26Z","timestamp":1783619726617,"version":"3.55.0"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,10,22]],"date-time":"2024-10-22T00:00:00Z","timestamp":1729555200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,10,22]],"date-time":"2024-10-22T00:00:00Z","timestamp":1729555200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["No. 32160874"],"award-info":[{"award-number":["No. 32160874"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Hainan Province Science and Technology Special Fund","award":["ZDKJ2021016"],"award-info":[{"award-number":["ZDKJ2021016"]}]},{"DOI":"10.13039\/501100012248","name":"Collaborative Innovation Center for Modern Science and Technology and Industrial Development of Jiangxi Traditional Medicine","doi-asserted-by":"publisher","award":["XTCX2022HYB03"],"award-info":[{"award-number":["XTCX2022HYB03"]}],"id":[{"id":"10.13039\/501100012248","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100022719","name":"Environment and Ecology Bureau","doi-asserted-by":"publisher","award":["No. ZLHX2018-124R"],"award-info":[{"award-number":["No. ZLHX2018-124R"]}],"id":[{"id":"10.13039\/100022719","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Genes Genom"],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.1007\/s13258-024-01541-7","type":"journal-article","created":{"date-parts":[[2024,10,22]],"date-time":"2024-10-22T12:02:39Z","timestamp":1729598559000},"page":"37-46","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Transcriptome analysis of tilapia streptococcus agalactiae in response to baicalin"],"prefix":"10.1007","volume":"47","author":[{"given":"Qing-Qin","family":"Huang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shao-Long","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji-Hui","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zi-Chen","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heng-Wei","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuan","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei-Liang","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi-Hong","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian-Long","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong-Dong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shi-Feng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong-Can","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,10,22]]},"reference":[{"key":"1541_CR3","doi-asserted-by":"publisher","first-page":"3136","DOI":"10.1099\/mic.0.039586-0","volume":"156","author":"S-J Ahn","year":"2010","unstructured":"Ahn S-J, Rice KC, Oleas J, Bayles KW, Burne RA (2010) The Streptococcus mutans cid and Lrg systems modulate virulence traits in response to multiple environmental signals. Microbiology 156:3136\u20133147. https:\/\/doi.org\/10.1099\/mic.0.039586-0","journal-title":"Microbiology"},{"key":"1541_CR2","doi-asserted-by":"publisher","first-page":"14063","DOI":"10.1038\/s41598-017-14324-w","volume":"7","author":"S-J Ahn","year":"2017","unstructured":"Ahn S-J, Gu T, Koh J, Rice KC (2017) Remodeling of the Streptococcus mutans proteome in response to LrgAB and external stresses. Sci Rep 7:14063. https:\/\/doi.org\/10.1038\/s41598-017-14324-w","journal-title":"Sci Rep"},{"key":"1541_CR1","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1186\/s12866-019-1600-x","volume":"19","author":"S-J Ahn","year":"2019","unstructured":"Ahn S-J, Deep K, Turner ME, Ishkov I, Waters A, Hagen SJ, Rice KC (2019) Characterization of LrgAB as a stationary phase-specific pyruvate uptake system in Streptococcus mutans. BMC Microbiol 19:223. https:\/\/doi.org\/10.1186\/s12866-019-1600-x","journal-title":"BMC Microbiol"},{"key":"1541_CR4","doi-asserted-by":"publisher","first-page":"3123","DOI":"10.3389\/fmicb.2019.03123","volume":"10","author":"B Armistead","year":"2020","unstructured":"Armistead B, Whidbey C, Iyer LM, Herrero-Foncubierta P, Quach P, Haidour A, Aravind L, Cuerva JM, Jaspan HB, Rajagopal L (2020) The cyl genes reveal the Biosynthetic and Evolutionary origins of the Group B Streptococcus hemolytic lipid, Granadaene. Front Microbiol 10:3123. https:\/\/doi.org\/10.3389\/fmicb.2019.03123","journal-title":"Front Microbiol"},{"key":"1541_CR5","doi-asserted-by":"publisher","first-page":"5810","DOI":"10.1128\/jb.178.19.5810-5812.1996","volume":"178","author":"EW Brunskill","year":"1996","unstructured":"Brunskill EW, Bayles KW (1996) Identification of LytSR-regulated genes from Staphylococcus aureus. J Bacteriol 178:5810\u20135812. https:\/\/doi.org\/10.1128\/jb.178.19.5810-5812.1996","journal-title":"J Bacteriol"},{"key":"1541_CR6","doi-asserted-by":"publisher","first-page":"e127","DOI":"10.1016\/S1473-3099(16)00100-6","volume":"16","author":"FC Cabello","year":"2016","unstructured":"Cabello FC, Godfrey HP, Buschmann AH, D\u00f6lz HJ (2016) Aquaculture as yet another environmental gateway to the development and globalisation of antimicrobial resistance. Lancet Infect Dis 16:e127\u2013e133. https:\/\/doi.org\/10.1016\/S1473-3099(16)00100-6","journal-title":"Lancet Infect Dis"},{"key":"1541_CR7","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1016\/S0006-2952(99)00243-9","volume":"59","author":"J Chang","year":"2000","unstructured":"Chang J (2000) Medicinal herbs: drugs or dietary supplements? Biochem Pharmacol 59:211\u2013219. https:\/\/doi.org\/10.1016\/S0006-2952(99)00243-9","journal-title":"Biochem Pharmacol"},{"key":"1541_CR8","doi-asserted-by":"publisher","first-page":"526","DOI":"10.1016\/j.vetmic.2012.04.035","volume":"159","author":"M Chen","year":"2012","unstructured":"Chen M, Li L-P, Wang R, Liang W-W, Huang Y, Li J, Lei A-Y, Huang W-Y, Gan X (2012) PCR detection and PFGE genotype analyses of streptococcal clinical isolates from tilapia in China. Vet Microbiol 159:526\u2013530. https:\/\/doi.org\/10.1016\/j.vetmic.2012.04.035","journal-title":"Vet Microbiol"},{"key":"1541_CR9","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1007\/s10499-009-9253-7","volume":"18","author":"T Citarasu","year":"2010","unstructured":"Citarasu T (2010) Herbal biomedicines: a new opportunity for aquaculture industry. Aquacultrue Int 18:403\u2013414. https:\/\/doi.org\/10.1007\/s10499-009-9253-7","journal-title":"Aquacultrue Int"},{"key":"1541_CR10","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1186\/1471-2180-11-86","volume":"11","author":"LF Dawson","year":"2011","unstructured":"Dawson LF, Donahue EH, Cartman ST, Barton RH, Bundy J, McNerney R, Minton NP, Wren BW (2011) The analysis of para-cresol production and tolerance in Clostridium difficile 027 and 012 strains. BMC Microbiol 11:86. https:\/\/doi.org\/10.1186\/1471-2180-11-86","journal-title":"BMC Microbiol"},{"key":"1541_CR11","doi-asserted-by":"publisher","first-page":"736","DOI":"10.1172\/JCI200317335","volume":"112","author":"KS Doran","year":"2003","unstructured":"Doran KS, Liu GY, Nizet V (2003) Group B streptococcal \u03b2-hemolysin\/cytolysin activates neutrophil signaling pathways in brain endothelium and contributes to development of meningitis. J Clin Invest 112:736\u2013744. https:\/\/doi.org\/10.1172\/JCI200317335","journal-title":"J Clin Invest"},{"key":"1541_CR12","doi-asserted-by":"publisher","unstructured":"Elliott JA, Facklam RR, Richter CB (1989) Whole-cell protein patterns of Nonhemolytic Group B, Type Lb, Streptococci isolated from humans, mice, cattle, frogs, and Fish. J Clin Microbiol 28:628\u2013630. https:\/\/doi.org\/10.1128\/jcm.28.3.628-630.1990","DOI":"10.1128\/jcm.28.3.628-630.1990"},{"key":"1541_CR13","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1046\/j.1365-2761.2002.00392.x","volume":"25","author":"JJ Evans","year":"2002","unstructured":"Evans JJ, Klesius PH, Gilbert PM, Shoemaker CA, Al Sarawi MA, Landsberg J, Duremdez R, Al Marzouk A, Zenki A, S (2002) Characterization of beta-haemolytic Group B Streptococcus agalactiae in cultured seabream, Sparus auratus L., and wild mullet, Liza klunzingeri (Day), in Kuwait. J Fish Dis 25:505\u2013513. https:\/\/doi.org\/10.1046\/j.1365-2761.2002.00392.x","journal-title":"J Fish Dis"},{"key":"1541_CR14","doi-asserted-by":"publisher","first-page":"1758","DOI":"10.1039\/c0np00005a","volume":"27","author":"H Ge","year":"2010","unstructured":"Ge H, Wang Y-F, Xu J, Gu Q, Liu H-B, Xiao P-G, Zhou J, Liu Y, Yang Z, Su H (2010) Anti-influenza agents from traditional Chinese medicine. Nat Prod Rep 27:1758. https:\/\/doi.org\/10.1039\/c0np00005a","journal-title":"Nat Prod Rep"},{"key":"1541_CR15","doi-asserted-by":"publisher","first-page":"5984","DOI":"10.1128\/JB.00768-05","volume":"188","author":"B Gottschalk","year":"2006","unstructured":"Gottschalk B, Br\u00f6ker G, Kuhn M, Aymanns S, Gleich-Theurer U, Spellerberg B (2006) Transport of Multidrug Resistance substrates by the Streptococcus agalactiae Hemolysin Transporter. J Bacteriol 188:5984\u20135992. https:\/\/doi.org\/10.1128\/JB.00768-05","journal-title":"J Bacteriol"},{"key":"1541_CR16","doi-asserted-by":"publisher","first-page":"644","DOI":"10.1038\/nbt.1883","volume":"29","author":"MG Grabherr","year":"2011","unstructured":"Grabherr MG, Haas BJ, Yassour M, Levin JZ, Thompson DA, Amit I, Adiconis X, Fan L, Raychowdhury R, Zeng Q, Chen Z, Mauceli E, Hacohen N, Gnirke A, Rhind N, Di Palma F, Birren BW, Nusbaum C, Lindblad-Toh K, Friedman N, Regev A (2011) Full-length transcriptome assembly from RNA-Seq data without a reference genome. Nat Biotechnol 29:644\u2013652. https:\/\/doi.org\/10.1038\/nbt.1883","journal-title":"Nat Biotechnol"},{"key":"1541_CR18","doi-asserted-by":"publisher","first-page":"e2446","DOI":"10.1371\/journal.pone.0002446","volume":"3","author":"ME Hensler","year":"2008","unstructured":"Hensler ME, Miyamoto S, Nizet V (2008) Group B Streptococcal \u03b2-Hemolysin\/Cytolysin directly impairs cardiomyocyte viability and function. PLoS ONE 3:e2446. https:\/\/doi.org\/10.1371\/journal.pone.0002446","journal-title":"PLoS ONE"},{"key":"1541_CR17","doi-asserted-by":"publisher","unstructured":"Hensler ME, Liu GY, Sobczak S, Benirschke K, Nizet V, Heldt GP (2005) Virulence role of Group B Streptococcus b-Hemolysin\/Cytolysin in a neonatal rabbit model of early-onset pulmonary infection. J Infect Dis 191:1287\u20131291. https:\/\/doi.org\/10.1086\/428946","DOI":"10.1086\/428946"},{"key":"1541_CR19","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1111\/j.1365-2761.2008.00981.x","volume":"32","author":"E Hern\u00e1ndez","year":"2009","unstructured":"Hern\u00e1ndez E, Figueroa J, Iregui C (2009) Streptococcosis on a red tilapia, Oreochromis sp., farm: a case study. J Fish Dis 32:247\u2013252. https:\/\/doi.org\/10.1111\/j.1365-2761.2008.00981.x","journal-title":"J Fish Dis"},{"key":"1541_CR20","doi-asserted-by":"publisher","first-page":"105444","DOI":"10.1016\/j.phrs.2021.105444","volume":"165","author":"Q Hu","year":"2021","unstructured":"Hu Q, Zhang W, Wu Z, Tian X, Xiang J, Li L, Li Z, Peng X, Wei S, Ma X, Zhao Y (2021) Baicalin and the liver-gut system: pharmacological bases explaining its therapeutic effects. Pharmacol Res 165:105444. https:\/\/doi.org\/10.1016\/j.phrs.2021.105444","journal-title":"Pharmacol Res"},{"key":"1541_CR21","doi-asserted-by":"publisher","unstructured":"Jia M, Wei M, Zhang Y, Zheng C (2020) Transcriptomic analysis of Streptococcus suis in response to Ferrous Iron and Cobalt Toxicity. Genes 11:1035. https:\/\/doi.org\/10.20944\/preprints202008.0708.v1.","DOI":"10.20944\/preprints202008.0708.v1"},{"key":"1541_CR22","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/S0044-8486(02)00192-8","volume":"218","author":"J Jian","year":"2003","unstructured":"Jian J, Wu Z (2003) Effects of traditional Chinese medicine on nonspecific immunity and disease resistance of large yellow croaker, Pseudosciaena crocea (Richardson). Aquaculture 218:1\u20139. https:\/\/doi.org\/10.1016\/S0044-8486(02)00192-8","journal-title":"Aquaculture"},{"key":"1541_CR23","doi-asserted-by":"publisher","first-page":"2530","DOI":"10.1128\/JCM.41.6.2530-2536.2003","volume":"41","author":"N Jones","year":"2003","unstructured":"Jones N, Bohnsack JF, Takahashi S, Oliver KA, Chan M-S, Kunst F, Glaser P, Rusniok C, Crook DWM, Harding RM, Bisharat N, Spratt BG (2003) Multilocus sequence typing system for Group B Streptococcus. J Clin Microbiol 41:2530\u20132536. https:\/\/doi.org\/10.1128\/JCM.41.6.2530-2536.2003","journal-title":"J Clin Microbiol"},{"key":"1541_CR24","doi-asserted-by":"publisher","unstructured":"Larsson C, St\u00e5lhammar-Carlemalm M, Lindahl G (1996) Experimental vaccination against Group B Streptococcus, an Encapsulated Bacterium, with highly purified preparations of cell surface proteins Rib and \u03b1. Infect Immun 64:3518\u20133526. https:\/\/doi.org\/10.1128\/IAI.64.9.3518-3523.1996.","DOI":"10.1128\/IAI.64.9.3518-3523.1996"},{"key":"1541_CR25","doi-asserted-by":"publisher","unstructured":"Li B, Dewey CN (2011) RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome. BMC Bioinformatics 12:323.  https:\/\/doi.org\/10.1186\/1471-2105-12-323","DOI":"10.1186\/1471-2105-12-323"},{"key":"1541_CR26","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1016\/j.micpath.2019.03.025","volume":"130","author":"MC Lima","year":"2019","unstructured":"Lima MC, Paiva De Sousa C, Fernandez-Prada C, Harel J, Dubreuil JD, De Souza EL (2019) A review of the current evidence of fruit phenolic compounds as potential antimicrobials against pathogenic bacteria. Microb Pathog 130:259\u2013270. https:\/\/doi.org\/10.1016\/j.micpath.2019.03.025","journal-title":"Microb Pathog"},{"key":"1541_CR27","doi-asserted-by":"publisher","first-page":"6653","DOI":"10.1128\/JB.01788-12","volume":"194","author":"G Liu","year":"2012","unstructured":"Liu G, Zhang W, Lu C (2012) Complete genome sequence of Streptococcus agalactiae GD201008-001, isolated in China from Tilapia with Meningoencephalitis. J Bacteriol 194:6653\u20136653. https:\/\/doi.org\/10.1128\/JB.01788-12","journal-title":"J Bacteriol"},{"key":"1541_CR28","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1016\/j.vetmic.2008.10.016","volume":"136","author":"GF Mian","year":"2009","unstructured":"Mian GF, Godoy DT, Leal CAG, Yuhara TY, Costa GM, Figueiredo HCP (2009) Aspects of the natural history and virulence of S. agalactiae infection in Nile tilapia. Vet Microbiol 136:180\u2013183. https:\/\/doi.org\/10.1016\/j.vetmic.2008.10.016","journal-title":"Vet Microbiol"},{"key":"1541_CR29","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1038\/nature12503","volume":"502","author":"KM Ng","year":"2013","unstructured":"Ng KM, Ferreyra JA, Higginbottom SK, Lynch JB, Kashyap PC, Gopinath S, Naidu N, Choudhury B, Weimer BC, Monack DM, Sonnenburg JL (2013) Microbiota-liberated host sugars facilitate post-antibiotic expansion of enteric pathogens. Nature 502:96\u201399. https:\/\/doi.org\/10.1038\/nature12503","journal-title":"Nature"},{"key":"1541_CR30","doi-asserted-by":"publisher","first-page":"1395","DOI":"10.1111\/j.1365-2958.2006.05034.x","volume":"59","author":"TG Patton","year":"2006","unstructured":"Patton TG, Yang S-J, Bayles KW (2006) The role of proton motive force in expression of the Staphylococcus aureus cid and lrg operons: \u2206\u03a8-induced gene expression in Staphylococcus aureus. Mol Microbiol 59:1395\u20131404. https:\/\/doi.org\/10.1111\/j.1365-2958.2006.05034.x","journal-title":"Mol Microbiol"},{"key":"1541_CR31","doi-asserted-by":"publisher","DOI":"10.1046\/J.1365-2958.2001.02211.X","author":"CA Pritzlaff","year":"2001","unstructured":"Pritzlaff CA, Chang JCW, Kuo SP, Tamura GS, Rubens CE, Nizet V (2001) Genetic basis for the \u03b2-haemolytic\/cytolytic activity of group B Streptococcus. Mol Microbiol 39: 236\u2013248. https:\/\/doi.org\/10.1046\/J.1365-2958.2001.02211.X","journal-title":"Mol Microbiol"},{"key":"1541_CR32","doi-asserted-by":"publisher","first-page":"824","DOI":"10.1086\/315773","volume":"182","author":"M Puliti","year":"2000","unstructured":"Puliti M, Nizet V, von Hunolstein C, Bistoni F, Mosci P, Orefici G, Tissi L (2000) Severity of Group B Streptococcal Arthritis is correlated with \u03b2-Hemolysin expression. J Infect Dis 182:824\u2013832. https:\/\/doi.org\/10.1086\/315773","journal-title":"J Infect Dis"},{"key":"1541_CR33","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1093\/infdis\/jis336","volume":"206","author":"J Qiu","year":"2012","unstructured":"Qiu J, Niu X, Dong J, Wang D, Wang J, Li H, Luo M, Li S, Feng H, Deng X (2012) Baicalin protects mice from Staphylococcus aureus Pneumonia Via Inhibition of the cytolytic activity of \u03b1-Hemolysin. J Infect Dis 206:292\u2013301. https:\/\/doi.org\/10.1093\/infdis\/jis336","journal-title":"J Infect Dis"},{"key":"1541_CR34","doi-asserted-by":"publisher","unstructured":"Ring A, Braun JS, Nizet V, Stremmel W, Shenep JL (2002) Group B streptococcal b-Hemolysin induces mortality and liver injury in experimental sepsis. J Infect Dis 185:1745\u20131753. https:\/\/doi.org\/10.1086\/340818","DOI":"10.1086\/340818"},{"key":"1541_CR35","doi-asserted-by":"publisher","first-page":"932","DOI":"10.1111\/1574-6976.12071","volume":"38","author":"M Rosa-Fraile","year":"2014","unstructured":"Rosa-Fraile M, Dramsi S, Spellerberg B (2014) Group B streptococcal haemolysin and pigment, a tale of twins. FEMS Microbiol Rev 38:932\u2013946. https:\/\/doi.org\/10.1111\/1574-6976.12071","journal-title":"FEMS Microbiol Rev"},{"key":"1541_CR36","doi-asserted-by":"publisher","first-page":"5992","DOI":"10.1128\/jb.173.19.5992-5998.1991","volume":"173","author":"EL Rosey","year":"1991","unstructured":"Rosey EL, Oskouian B, Stewart GC (1991) Lactose metabolism by Staphylococcus aureus: characterization of lacABCD, the structural genes of the tagatose 6-phosphate pathway. J Bacteriol 173:5992\u20135998. https:\/\/doi.org\/10.1128\/jb.173.19.5992-5998.1991","journal-title":"J Bacteriol"},{"key":"1541_CR37","doi-asserted-by":"publisher","first-page":"2230711","DOI":"10.1080\/20002297.2023.2230711","volume":"15","author":"L Rudin","year":"2023","unstructured":"Rudin L, Bornstein MM, Shyp V (2023) Inhibition of biofilm formation and virulence factors of cariogenic oral pathogen Streptococcus mutans by natural flavonoid phloretin. J Oral Microbiol 15:2230711. https:\/\/doi.org\/10.1080\/20002297.2023.2230711","journal-title":"J Oral Microbiol"},{"key":"1541_CR38","doi-asserted-by":"publisher","first-page":"3212","DOI":"10.1128\/JB.181.10.3212-3219.1999","volume":"181","author":"B Spellerberg","year":"1999","unstructured":"Spellerberg B, Pohl B, Haase G, Martin S, Weber-Heynemann J, L\u00fctticken R (1999) Identification of genetic determinants for the hemolytic activity of Streptococcus agalactiae by IS S1 transposition. J Bacteriol 181:3212\u20133219. https:\/\/doi.org\/10.1128\/JB.181.10.3212-3219.1999","journal-title":"J Bacteriol"},{"key":"1541_CR39","doi-asserted-by":"publisher","first-page":"901","DOI":"10.3389\/fmicb.2018.00901","volume":"9","author":"M Steglich","year":"2018","unstructured":"Steglich M, Hofmann JD, Helmecke J, Sikorski J, Spr\u00f6er C, Riedel T, Bunk B, Overmann J, Neumann-Schaal M, N\u00fcbel U (2018) Convergent loss of ABC transporter genes from Clostridioides difficile genomes is Associated with impaired tyrosine uptake and p-Cresol production. Front Microbiol 9:901. https:\/\/doi.org\/10.3389\/fmicb.2018.00901","journal-title":"Front Microbiol"},{"key":"1541_CR40","doi-asserted-by":"publisher","first-page":"e00931","DOI":"10.1128\/IAI.00931-19","volume":"88","author":"L Thomas","year":"2020","unstructured":"Thomas L, Cook L (2020) Two-Component Signal Transduction Systems in the Human Pathogen Streptococcus agalactiae. Infect Immun 88:e00931\u2013e00919. https:\/\/doi.org\/10.1128\/IAI.00931-19","journal-title":"Infect Immun"},{"key":"1541_CR41","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1097\/01.inf.0000111212.94913.5f","volume":"23","author":"MAJM Trijbels-Smeulders","year":"2004","unstructured":"Trijbels-Smeulders MAJM, Koll\u00e9e LAA, Adriaanse AH, Kimpen JLL, Gerards LJ (2004) Neonatal group B streptococcal infection: incidence and strategies for prevention in Europe. Pediatr Infect Dis J 23:172\u2013173. https:\/\/doi.org\/10.1097\/01.inf.0000111212.94913.5f","journal-title":"Pediatr Infect Dis J"},{"key":"1541_CR42","doi-asserted-by":"publisher","first-page":"734645","DOI":"10.1016\/j.aquaculture.2019.734645","volume":"516","author":"F Wang","year":"2020","unstructured":"Wang F, Xian X-R, Guo W-L, Zhong Z-H, Wang S-F, Cai Y, Sun Y, Chen X, Wang Y, Zhou Y-C (2020) Baicalin attenuates Streptococcus agalactiae virulence and protects tilapia (Oreochromis niloticus) from group B streptococcal infection. Aquaculture 516:734645. https:\/\/doi.org\/10.1016\/j.aquaculture.2019.734645","journal-title":"Aquaculture"},{"key":"1541_CR43","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/j.aquaculture.2014.02.027","volume":"428\u2013429","author":"T Yi","year":"2014","unstructured":"Yi T, Li Y-W, Liu L, Xiao X-X, Li A-X (2014) Protection of Nile tilapia (Oreochromis niloticus L.) against Streptococcus agalactiae following immunization with recombinant FbsA and \u03b1-enolase. Aquaculture 428\u2013429:35\u201340. https:\/\/doi.org\/10.1016\/j.aquaculture.2014.02.027","journal-title":"Aquaculture"},{"key":"1541_CR44","doi-asserted-by":"publisher","first-page":"146348","DOI":"10.1016\/j.scitotenv.2021.146348","volume":"778","author":"X Zhao","year":"2021","unstructured":"Zhao X, Su H, Xu W, Hu X, Xu Y, Wen G, Cao Y (2021) Removal of antibiotic resistance genes and inactivation of antibiotic-resistant bacteria by oxidative treatments. Sci Total Environ 778:146348. https:\/\/doi.org\/10.1016\/j.scitotenv.2021.146348","journal-title":"Sci Total Environ"}],"container-title":["Genes &amp; Genomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13258-024-01541-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s13258-024-01541-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13258-024-01541-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,15]],"date-time":"2025-01-15T08:26:54Z","timestamp":1736929614000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s13258-024-01541-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,22]]},"references-count":44,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["1541"],"URL":"https:\/\/doi.org\/10.1007\/s13258-024-01541-7","relation":{},"ISSN":["1976-9571","2092-9293"],"issn-type":[{"value":"1976-9571","type":"print"},{"value":"2092-9293","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,22]]},"assertion":[{"value":"28 November 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 May 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 October 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have declared no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}