{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T13:43:28Z","timestamp":1793281408782,"version":"4.5.0"},"reference-count":59,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T00:00:00Z","timestamp":1790553600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T00:00:00Z","timestamp":1790553600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"the national research foundation of korea","award":["RS-2025-00556948"],"award-info":[{"award-number":["RS-2025-00556948"]}],"id":[{"id":"https:\/\/ror.org\/013aysd81","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Genes Genom"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1007\/s13258-026-01810-7","type":"journal-article","created":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T12:00:56Z","timestamp":1790596856000},"page":"1453-1464","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["KIF18A knockdown enhances oxidative phosphorylation, suggesting a metabolic basis for antiviral activity against influenza A virus"],"prefix":"10.1007","volume":"48","author":[{"given":"Hyeong-Rae","family":"Kim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiwon","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongju","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"In-Gu","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Younghyun","family":"Lim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeonghyeon","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seungyeon","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"So-Hee","family":"Hong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8744-8083","authenticated-orcid":false,"given":"Young-Jin","family":"Seo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,9,28]]},"reference":[{"key":"1810_CR1","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1126\/science.aaa3778","volume":"348","author":"E Bekerman","year":"2015","unstructured":"Bekerman E, Einav S (2015) Infectious disease. Combating emerging viral threats. Science 348:282\u2013283","journal-title":"Science"},{"key":"1810_CR2","doi-asserted-by":"publisher","first-page":"1619","DOI":"10.1038\/s41592-023-02014-7","volume":"20","author":"AS Castanza","year":"2023","unstructured":"Castanza AS, Recla JM, Eby D, Thorvaldsdottir H, Bult CJ, Mesirov JP (2023) Extending support for mouse data in the Molecular Signatures Database (MSigDB). Nat Methods 20:1619\u20131620","journal-title":"Nat Methods"},{"key":"1810_CR4","doi-asserted-by":"publisher","first-page":"i884","DOI":"10.1093\/bioinformatics\/bty560","volume":"34","author":"S Chen","year":"2018","unstructured":"Chen S, Zhou Y, Chen Y, Gu J (2018) fastp: an ultra-fast all-in-one FASTQ preprocessor. Bioinformatics 34:i884\u2013i890","journal-title":"Bioinformatics"},{"key":"1810_CR3","doi-asserted-by":"crossref","unstructured":"Chen CW, Liao WT, Chao T, Chen YH, Weng SC, Shiao SH, Kao CY, Li YJ, Cheng KA, Chang ZF (2026) An engineered viral RNA degrader on mitochondrial surface that mitigates RNA virus infection. Nat Commun 17","DOI":"10.1038\/s41467-026-73487-1"},{"key":"1810_CR5","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1038\/ni.2766","volume":"15","author":"HS Chiang","year":"2014","unstructured":"Chiang HS, Zhao Y, Song JH, Liu S, Wang N, Terhorst C, Sharpe AH, Basavappa M, Jeffrey KL, Reinecker HC (2014) GEF-H1 controls microtubule-dependent sensing of nucleic acids for antiviral host defenses. Nat Immunol 15:63\u201371","journal-title":"Nat Immunol"},{"key":"1810_CR6","doi-asserted-by":"publisher","first-page":"5463","DOI":"10.1111\/jcmm.15200","volume":"24","author":"YB Cho","year":"2020","unstructured":"Cho YB, Hong S, Kang KW, Kang JH, Lee SM, Seo YJ (2020) Selective and ATP-competitive kinesin KIF18A inhibitor suppresses the replication of influenza A virus. J Cell Mol Med 24:5463\u20135475","journal-title":"J Cell Mol Med"},{"key":"1810_CR7","doi-asserted-by":"publisher","first-page":"e1005700","DOI":"10.1371\/journal.ppat.1005700","volume":"12","author":"A Dharan","year":"2016","unstructured":"Dharan A, Talley S, Tripathi A, Mamede JI, Majetschak M, Hope TJ, Campbell EM (2016) KIF5B and Nup358 cooperatively mediate the nuclear import of HIV-1 during Infection. PLoS Pathog 12:e1005700","journal-title":"PLoS Pathog"},{"key":"1810_CR8","doi-asserted-by":"publisher","first-page":"3527","DOI":"10.1038\/emboj.2011.283","volume":"30","author":"MP Dodding","year":"2011","unstructured":"Dodding MP, Way M (2011) Coupling viruses to dynein and kinesin-1. EMBO J 30:3527\u20133539","journal-title":"EMBO J"},{"key":"1810_CR9","doi-asserted-by":"crossref","unstructured":"DuRaine G, Wisner TW, Howard P, Johnson DC (2018) Kinesin-1 proteins KIF5A, -5B, and -5C promote anterograde transport of herpes simplex virus enveloped virions in axons. J Virol 92","DOI":"10.1128\/JVI.01269-18"},{"key":"1810_CR10","doi-asserted-by":"publisher","first-page":"eadu3739","DOI":"10.1126\/sciadv.adu3739","volume":"11","author":"AL Fuchs","year":"2025","unstructured":"Fuchs AL, Singh B, Jetmore JW, Warren EB, Banerjee P, Marin Franco JL, Eckhaus MA, Tarasenko TN, Assaad MR, Kosik I et al (2025) Mitochondrial dysfunction enhances influenza pathogenesis by up-regulating de novo sialic acid biosynthesis. Sci Adv 11:eadu3739","journal-title":"Sci Adv"},{"key":"1810_CR11","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/j.ceb.2008.12.002","volume":"21","author":"A Gennerich","year":"2009","unstructured":"Gennerich A, Vale RD (2009) Walking the walk: how kinesin and dynein coordinate their steps. Curr Opin Cell Biol 21:59\u201367","journal-title":"Curr Opin Cell Biol"},{"key":"1810_CR12","doi-asserted-by":"publisher","first-page":"e1003298","DOI":"10.1371\/journal.ppat.1003298","volume":"9","author":"ML Goulet","year":"2013","unstructured":"Goulet ML, Olagnier D, Xu Z, Paz S, Belgnaoui SM, Lafferty EI, Janelle V, Arguello M, Paquet M, Ghneim K et al (2013) Systems analysis of a RIG-I agonist inducing broad spectrum inhibition of virus infectivity. PLoS Pathog 9:e1003298","journal-title":"PLoS Pathog"},{"key":"1810_CR13","doi-asserted-by":"publisher","first-page":"23","DOI":"10.2217\/fmb.09.108","volume":"5","author":"BG Hale","year":"2010","unstructured":"Hale BG, Albrecht RA, Garcia-Sastre A (2010) Innate immune evasion strategies of influenza viruses. Future Microbiol 5:23\u201341","journal-title":"Future Microbiol"},{"key":"1810_CR14","doi-asserted-by":"publisher","first-page":"3861","DOI":"10.1073\/pnas.1522376113","volume":"113","author":"JR Hamilton","year":"2016","unstructured":"Hamilton JR, Sachs D, Lim JK, Langlois RA, Palese P, Heaton NS (2016) Club cells surviving influenza A virus infection induce temporary nonspecific antiviral immunity. Proc Natl Acad Sci U S A 113:3861\u20133866","journal-title":"Proc Natl Acad Sci U S A"},{"key":"1810_CR15","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1038\/ni.1963","volume":"12","author":"S Hayakawa","year":"2011","unstructured":"Hayakawa S, Shiratori S, Yamato H, Kameyama T, Kitatsuji C, Kashigi F, Goto S, Kameoka S, Fujikura D, Yamada T et al (2011) ZAPS is a potent stimulator of signaling mediated by the RNA helicase RIG-I during antiviral responses. Nat Immunol 12:37\u201344","journal-title":"Nat Immunol"},{"key":"1810_CR16","doi-asserted-by":"publisher","first-page":"682","DOI":"10.1038\/nrm2774","volume":"10","author":"N Hirokawa","year":"2009","unstructured":"Hirokawa N, Noda Y, Tanaka Y, Niwa S (2009) Kinesin superfamily motor proteins and intracellular transport. Nat Rev Mol Cell Biol 10:682\u2013696","journal-title":"Nat Rev Mol Cell Biol"},{"key":"1810_CR17","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1016\/j.chom.2017.09.002","volume":"22","author":"HH Hoffmann","year":"2017","unstructured":"Hoffmann HH, Schneider WM, Blomen VA, Scull MA, Hovnanian A, Brummelkamp TR, Rice CM (2017) Diverse viruses require the calcium transporter SPCA1 for maturation and spread. Cell Host Microbe 22:460\u2013470e465","journal-title":"Cell Host Microbe"},{"key":"1810_CR18","doi-asserted-by":"publisher","first-page":"1113","DOI":"10.1007\/s12275-022-2436-x","volume":"60","author":"H Jeon","year":"2022","unstructured":"Jeon H, Lim Y, Lee IG, Kim DI, Kim KP, Hong SH, Kim J, Jung YS, Seo YJ (2022) Inhibition of KIF20A suppresses the replication of influenza A virus by inhibiting viral entry. J Microbiol 60:1113\u20131121","journal-title":"J Microbiol"},{"key":"1810_CR19","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1007\/s13273-021-00126-9","volume":"17","author":"DI Kim","year":"2021","unstructured":"Kim DI, Kang JH, Kim EH, Seo YJ (2021) KIF11 inhibition decreases cytopathogenesis and replication of influenza A virus. Mol Cell Toxicol 17:201\u2013212","journal-title":"Mol Cell Toxicol"},{"key":"1810_CR20","doi-asserted-by":"publisher","first-page":"616","DOI":"10.1016\/j.chom.2023.03.005","volume":"31","author":"S Klein","year":"2023","unstructured":"Klein S, Golani G, Lolicato F, Lahr C, Beyer D, Herrmann A, Wachsmuth-Melm M, Reddmann N, Brecht R, Hosseinzadeh M et al (2023) IFITM3 blocks influenza virus entry by sorting lipids and stabilizing hemifusion. Cell Host Microbe 31:616\u2013633 e620","journal-title":"Cell Host Microbe"},{"key":"1810_CR21","doi-asserted-by":"publisher","first-page":"1293","DOI":"10.1007\/s13258-024-01544-4","volume":"46","author":"EJ Ko","year":"2024","unstructured":"Ko EJ, Suh DS, Kim H, Lee JY, Eo WK, Kim H, Kim KH, Cha HJ (2024) Transcriptome analysis of the effect of HERV-K env gene knockout in ovarian cancer cell lines. Genes Genomics 46:1293\u20131301","journal-title":"Genes Genomics"},{"key":"1810_CR22","doi-asserted-by":"publisher","first-page":"1201","DOI":"10.1007\/s10096-020-03840-9","volume":"39","author":"T Lampejo","year":"2020","unstructured":"Lampejo T (2020) Influenza and antiviral resistance: an overview. Eur J Clin Microbiol Infect Dis 39:1201\u20131208","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"1810_CR24","doi-asserted-by":"publisher","first-page":"3662","DOI":"10.1016\/j.ymthe.2025.06.040","volume":"33","author":"IG Lee","year":"2025","unstructured":"Lee IG, Lee J, Kim HR, Lim Y, Yu HW, Kim TH, Hahm B, Kang HA, Hong SH, Seo YJ (2025a) Galectin-4 potentiates CD8+ T cell immunity by enhancing MHC-I expression on dendritic cells. Mol Ther 33:3662\u20133679","journal-title":"Mol Ther"},{"key":"1810_CR25","doi-asserted-by":"publisher","first-page":"e2503008","DOI":"10.71150\/jm.2503008","volume":"63","author":"J Lee","year":"2025","unstructured":"Lee J, Lim Y, Kim HR, Cho YB, Lee IG, Seo YJ (2025b) Inhibiting kinesin family member 20A disrupts Zika virus entry by blocking internalization. J Microbiol 63:e2503008","journal-title":"J Microbiol"},{"key":"1810_CR23","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1007\/s13258-025-01736-6","volume":"48","author":"IG Lee","year":"2026","unstructured":"Lee IG, Lee J, Bang JY, Seo YJ, Hong SH (2026) Lasting bone marrow defects imprinted by hyperglycemia shape the immunological characteristics of differentiated M1 and M2 macrophages. Genes Genomics 48:433\u2013444","journal-title":"Genes Genomics"},{"key":"1810_CR26","doi-asserted-by":"publisher","first-page":"817","DOI":"10.1007\/s13258-024-01516-8","volume":"46","author":"J Lei","year":"2024","unstructured":"Lei J, Aimaier G, Aisha Z, Zhang Y, Ma J (2024) eEF1A1 regulates the expression and alternative splicing of genes associated with Parkinson\u2019s disease in U251 cells. Genes Genomics 46:817\u2013829","journal-title":"Genes Genomics"},{"key":"1810_CR27","doi-asserted-by":"publisher","first-page":"e47","DOI":"10.1093\/nar\/gkz114","volume":"47","author":"Y Liao","year":"2019","unstructured":"Liao Y, Smyth GK, Shi W (2019) The R package Rsubread is easier, faster, cheaper and better for alignment and quantification of RNA sequencing reads. Nucleic Acids Res 47:e47","journal-title":"Nucleic Acids Res"},{"key":"1810_CR28","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1016\/j.cels.2015.12.004","volume":"1","author":"A Liberzon","year":"2015","unstructured":"Liberzon A, Birger C, Thorvaldsdottir H, Ghandi M, Mesirov JP, Tamayo P (2015) The Molecular Signatures Database (MSigDB) hallmark gene set collection. Cell Syst 1:417\u2013425","journal-title":"Cell Syst"},{"key":"1810_CR29","doi-asserted-by":"publisher","first-page":"506","DOI":"10.1080\/19768354.2024.2418332","volume":"28","author":"Y Lim","year":"2024","unstructured":"Lim Y, Cho YB, Seo YJ (2024) Emerging roles of cytoskeletal transport and scaffold systems in human viral propagation. Anim Cells Syst (Seoul) 28:506\u2013518","journal-title":"Anim Cells Syst (Seoul)"},{"key":"1810_CR30","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1038\/s41420-025-02437-5","volume":"11","author":"G Liu","year":"2025","unstructured":"Liu G, Zhang Y, Cao Z, Zhao Z (2025) Targeting KIF18A triggers antitumor immunity and enhances efficiency of PD-1 blockade in colorectal cancer with chromosomal instability phenotype. Cell Death Discov 11:130","journal-title":"Cell Death Discov"},{"key":"1810_CR31","doi-asserted-by":"publisher","first-page":"550","DOI":"10.1186\/s13059-014-0550-8","volume":"15","author":"MI Love","year":"2014","unstructured":"Love MI, Huber W, Anders S (2014) Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2. Genome Biol 15:550","journal-title":"Genome Biol"},{"key":"1810_CR32","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1016\/j.cophys.2018.03.003","volume":"3","author":"AS Moore","year":"2018","unstructured":"Moore AS, Holzbaur ELF (2018) Mitochondrial-cytoskeletal interactions: dynamic associations that facilitate network function and remodeling. Curr Opin Physiol 3:94\u2013100","journal-title":"Curr Opin Physiol"},{"key":"1810_CR33","doi-asserted-by":"publisher","first-page":"101674","DOI":"10.1016\/j.redox.2020.101674","volume":"37","author":"D Nolfi-Donegan","year":"2020","unstructured":"Nolfi-Donegan D, Braganza A, Shiva S (2020) Mitochondrial electron transport chain: oxidative phosphorylation, oxidant production, and methods of measurement. Redox Biol 37:101674","journal-title":"Redox Biol"},{"key":"1810_CR34","doi-asserted-by":"publisher","first-page":"10879","DOI":"10.1038\/s41598-020-67879-6","volume":"10","author":"M Ohno","year":"2020","unstructured":"Ohno M, Sekiya T, Nomura N, Daito TJ, Shingai M, Kida H (2020) Influenza virus infection affects insulin signaling, fatty acid-metabolizing enzyme expressions, and the tricarboxylic acid cycle in mice. Sci Rep 10:10879","journal-title":"Sci Rep"},{"key":"1810_CR35","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.mito.2010.08.006","volume":"11","author":"A Ohta","year":"2011","unstructured":"Ohta A, Nishiyama Y (2011) Mitochondria and viruses. Mitochondrion 11:1\u201312","journal-title":"Mitochondrion"},{"key":"1810_CR36","doi-asserted-by":"publisher","first-page":"1245","DOI":"10.1038\/s42255-022-00652-3","volume":"4","author":"CS Palmer","year":"2022","unstructured":"Palmer CS (2022) Innate metabolic responses against viral infections. Nat Metab 4:1245\u20131259","journal-title":"Nat Metab"},{"key":"1810_CR37","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1038\/s43018-023-00699-5","volume":"5","author":"M Payton","year":"2024","unstructured":"Payton M, Belmontes B, Hanestad K, Moriguchi J, Chen K, McCarter JD, Chung G, Ninniri MS, Sun J, Manoukian R et al (2024) Small-molecule inhibition of kinesin KIF18A reveals a mitotic vulnerability enriched in chromosomally unstable cancers. Nat Cancer 5:66\u201384","journal-title":"Nat Cancer"},{"key":"1810_CR38","unstructured":"pheatmap (2025) pheatmap: pretty heatmaps. 1.0.13 edn. The R Foundation\/GitHub"},{"key":"1810_CR39","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1038\/s41467-024-55300-z","volume":"16","author":"AF Phillips","year":"2025","unstructured":"Phillips AF, Zhang R, Jaffe M, Schulz R, Carty MC, Verma A, Feinberg TY, Arensman MD, Chiu A, Letso R et al (2025) Targeting chromosomally unstable tumors with a selective KIF18A inhibitor. Nat Commun 16:307","journal-title":"Nat Commun"},{"key":"1810_CR40","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1007\/s13258-025-01620-3","volume":"47","author":"A Prakash","year":"2025","unstructured":"Prakash A, Patel Y, Roy JK (2025) BRN3A, a transcription factor, regulates the expression of genes involved in biological processes shaping the HPV induced cervical cancer. Genes Genomics 47:487\u2013501","journal-title":"Genes Genomics"},{"key":"1810_CR41","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1111\/j.1462-5822.2005.00679.x","volume":"8","author":"K Radtke","year":"2006","unstructured":"Radtke K, Dohner K, Sodeik B (2006) Viral interactions with the cytoskeleton: a hitchhiker\u2019s guide to the cell. Cell Microbiol 8:387\u2013400","journal-title":"Cell Microbiol"},{"key":"1810_CR42","doi-asserted-by":"publisher","first-page":"4038","DOI":"10.1242\/jcs.210807","volume":"130","author":"A Ramos-Nascimento","year":"2017","unstructured":"Ramos-Nascimento A, Kellen B, Ferreira F, Alenquer M, Vale-Costa S, Raposo G, Delevoye C, Amorim MJ (2017) KIF13A mediates trafficking of influenza A virus ribonucleoproteins. J Cell Sci 130:4038\u20134050","journal-title":"J Cell Sci"},{"key":"1810_CR43","first-page":"153","volume":"82","author":"T Samji","year":"2009","unstructured":"Samji T (2009) Influenza A: understanding the viral life cycle. Yale J Biol Med 82:153\u2013159","journal-title":"Yale J Biol Med"},{"key":"1810_CR44","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1016\/j.virol.2015.02.038","volume":"479\u2013480","author":"EL Sanchez","year":"2015","unstructured":"Sanchez EL, Lagunoff M (2015) Viral activation of cellular metabolism. Virology 479\u2013480:609\u2013618","journal-title":"Virology"},{"key":"1810_CR45","doi-asserted-by":"publisher","first-page":"669","DOI":"10.1016\/j.cell.2005.08.012","volume":"122","author":"RB Seth","year":"2005","unstructured":"Seth RB, Sun LJ, Ea CK, Chen ZJJ (2005) Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-\u03baB and IRF3. Cell 122:669\u2013682","journal-title":"Cell"},{"key":"1810_CR46","doi-asserted-by":"publisher","first-page":"3969","DOI":"10.1007\/s00018-021-03762-5","volume":"78","author":"M Shah","year":"2021","unstructured":"Shah M, Chacko LA, Joseph JP, Ananthanarayanan V (2021) Mitochondrial dynamics, positioning and function mediated by cytoskeletal interactions. Cell Mol Life Sci 78:3969\u20133986","journal-title":"Cell Mol Life Sci"},{"key":"1810_CR47","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1016\/S0966-842X(00)01824-2","volume":"8","author":"B Sodeik","year":"2000","unstructured":"Sodeik B (2000) Mechanisms of viral transport in the cytoplasm. Trends Microbiol 8:465\u2013472","journal-title":"Trends Microbiol"},{"key":"1810_CR48","doi-asserted-by":"publisher","first-page":"745","DOI":"10.1038\/s41556-018-0124-1","volume":"20","author":"JB Spinelli","year":"2018","unstructured":"Spinelli JB, Haigis MC (2018) The multifaceted contributions of mitochondria to cellular metabolism. Nat Cell Biol 20:745\u2013754","journal-title":"Nat Cell Biol"},{"key":"1810_CR49","doi-asserted-by":"publisher","first-page":"15545","DOI":"10.1073\/pnas.0506580102","volume":"102","author":"A Subramanian","year":"2005","unstructured":"Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, Gillette MA, Paulovich A, Pomeroy SL, Golub TR, Lander ES et al (2005) Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A 102:15545\u201315550","journal-title":"Proc Natl Acad Sci U S A"},{"key":"1810_CR50","doi-asserted-by":"crossref","unstructured":"Sullivan OM, Nesbitt DJ, Schaack GA, Feltman E, Nipper T, Kongsomros S, Reed SG, Nelson SL, King CR, Shishkova E et al (2025) IFIT3 RNA-binding activity promotes influenza A virus infection and translation efficiency. bioRxiv","DOI":"10.1101\/2025.02.17.638785"},{"key":"1810_CR51","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1186\/s12915-019-0678-9","volume":"17","author":"SK Thaker","year":"2019","unstructured":"Thaker SK, Ch\u2019ng J, Christofk HR (2019) Viral hijacking of cellular metabolism. BMC Biol 17:59","journal-title":"BMC Biol"},{"key":"1810_CR59","doi-asserted-by":"crossref","unstructured":"Tran V, Ledwith MP, Thamamongood T, et al. (2020) Influenza virus repurposes the antiviral protein IFIT2 to promote translation of viral mRNAs. Nat Microbiol 5:1490\u20131503","DOI":"10.1038\/s41564-020-0778-x"},{"key":"1810_CR52","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1080\/13543784.2026.2616752","volume":"35","author":"JQ Truong","year":"2026","unstructured":"Truong JQ, Galper T, Holien JK (2026) KIF18A inhibition and its rising role in cancer therapy trials: from bench to bedside. Expert Opin Investig Drugs 35:9\u201318","journal-title":"Expert Opin Investig Drugs"},{"key":"1810_CR53","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1172\/JCI44947","volume":"121","author":"DM Tscherne","year":"2011","unstructured":"Tscherne DM, Garcia-Sastre A (2011) Virulence determinants of pandemic influenza viruses. J Clin Invest 121:6\u201313","journal-title":"J Clin Invest"},{"key":"1810_CR54","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1016\/j.chom.2010.05.008","volume":"7","author":"T Watanabe","year":"2010","unstructured":"Watanabe T, Watanabe S, Kawaoka Y (2010) Cellular networks involved in the influenza virus life cycle. Cell Host Microbe 7:427\u2013439","journal-title":"Cell Host Microbe"},{"key":"1810_CR55","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1038\/nri2975","volume":"11","author":"AP West","year":"2011","unstructured":"West AP, Shadel GS, Ghosh S (2011) Mitochondria in innate immune responses. Nat Rev Immunol 11:389\u2013402","journal-title":"Nat Rev Immunol"},{"key":"1810_CR56","unstructured":"Wickham H, Sievert C, SpringerLink (2016) ggplot2: elegant graphics for data analysis. 2nd 2016. edn., Cham"},{"key":"1810_CR57","first-page":"100141","volume":"2","author":"T Wu","year":"2021","unstructured":"Wu T, Hu E, Xu S, Chen M, Guo P, Dai Z, Feng T, Zhou L, Tang W, Zhan L et al (2021) clusterProfiler 4.0: a universal enrichment tool for interpreting omics data. Innov (Camb) 2:100141","journal-title":"Innov (Camb)"},{"key":"1810_CR58","doi-asserted-by":"publisher","first-page":"5379","DOI":"10.1038\/s41598-017-05808-w","volume":"7","author":"T Yoshizumi","year":"2017","unstructured":"Yoshizumi T, Imamura H, Taku T, Kuroki T, Kawaguchi A, Ishikawa K, Nakada K, Koshiba T (2017) RLR-mediated antiviral innate immunity requires oxidative phosphorylation activity. Sci Rep 7:5379","journal-title":"Sci Rep"}],"container-title":["Genes & Genomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13258-026-01810-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s13258-026-01810-7","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13258-026-01810-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T13:16:46Z","timestamp":1793279806000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s13258-026-01810-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,28]]},"references-count":59,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2026,11]]}},"alternative-id":["1810"],"URL":"https:\/\/doi.org\/10.1007\/s13258-026-01810-7","relation":{},"ISSN":["1976-9571","2092-9293"],"issn-type":[{"value":"1976-9571","type":"print"},{"value":"2092-9293","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,28]]},"assertion":[{"value":"22 July 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 September 2026","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 September 2026","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 September 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no conflicts of interest.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","label":"Ethical approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":3,"name":"Ethics","label":"Informed consent","group":{"name":"EthicsHeading","label":"Declarations"}}]}}