{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T09:46:00Z","timestamp":1778838360386,"version":"3.51.4"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2013,3,1]],"date-time":"2013-03-01T00:00:00Z","timestamp":1362096000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tumor Biol."],"published-print":{"date-parts":[[2013,6]]},"DOI":"10.1007\/s13277-012-0584-z","type":"journal-article","created":{"date-parts":[[2013,2,28]],"date-time":"2013-02-28T16:04:18Z","timestamp":1362067458000},"page":"1391-1397","source":"Crossref","is-referenced-by-count":16,"title":["The effects of Hsp90 expression alteration on spinal metastases of breast carcinoma"],"prefix":"10.1007","volume":"34","author":[{"given":"Wangjun","family":"Yan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianru","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tielong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wending","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinghai","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhipeng","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Quan","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming","family":"Qian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2013,3,1]]},"reference":[{"issue":"3","key":"584_CR1","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.canep.2012.02.007","volume":"36","author":"DR Youlden","year":"2012","unstructured":"Youlden DR, Cramb SM, Dunn NAM, Muller JM, Pyke CM, Baade PD. The descriptive epidemiology of female breast cancer: an international comparison of screening, incidence, survival and mortality. Cancer Epidemiol. 2012;36(3):237\u201348.","journal-title":"Cancer Epidemiol"},{"issue":"8","key":"584_CR2","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1038\/nrc867","volume":"2","author":"GR Mundy","year":"2002","unstructured":"Mundy GR. Metastasis to bone: causes, consequences and therapeutic opportunities. Nat Rev Cancer. 2002;2(8):584\u201393.","journal-title":"Nat Rev Cancer"},{"issue":"2","key":"584_CR3","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1007\/s10911-005-5399-8","volume":"10","author":"W Kozlow","year":"2005","unstructured":"Kozlow W, Guise TA. Breast cancer metastasis to bone: mechanisms of osteolysis and implications for therapy. J Mammary Gland Biol Neoplasia. 2005;10(2):169\u201380.","journal-title":"J Mammary Gland Biol Neoplasia"},{"issue":"4","key":"584_CR4","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/S0030-5898(05)70173-5","volume":"31","author":"JM Salmon","year":"2000","unstructured":"Salmon JM, Kilpatrick SE. Pathology of skeletal metastases. Orthop Clin North Am. 2000;31(4):537\u201344. vii-viii.","journal-title":"Orthop Clin North Am"},{"issue":"19","key":"584_CR5","doi-asserted-by":"crossref","first-page":"1564","DOI":"10.1093\/jnci\/92.19.1564","volume":"92","author":"C Jolly","year":"2000","unstructured":"Jolly C, Morimoto RI. Role of the heat shock response and molecular chaperones in oncogenesis and cell death. J Natl Cancer Inst. 2000;92(19):1564\u201372.","journal-title":"J Natl Cancer Inst"},{"issue":"3","key":"584_CR6","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1006\/bbrc.2002.6476","volume":"291","author":"K Stangl","year":"2002","unstructured":"Stangl K, Gunther C, Frank T, Lorenz M, Meiners S, Ropke T, Stelter L, Moobed M, Baumann G, Kloetzel PM, et al. Inhibition of the ubiquitin\u2013proteasome pathway induces differential heat-shock protein response in cardiomyocytes and renders early cardiac protection. Biochem Biophys Res Commun. 2002;291(3):542\u20139.","journal-title":"Biochem Biophys Res Commun"},{"issue":"24","key":"584_CR7","doi-asserted-by":"crossref","first-page":"13791","DOI":"10.1073\/pnas.2434345100","volume":"100","author":"P Fortugno","year":"2003","unstructured":"Fortugno P, Beltrami E, Plescia J, Fontana J, Pradhan D, Marchisio PC, Sessa WC, Altieri DC. Regulation of survivin function by Hsp90. Proc Natl Acad Sci U S A. 2003;100(24):13791.","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"6","key":"584_CR8","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1093\/carcin\/bgm047","volume":"28","author":"M Pennati","year":"2007","unstructured":"Pennati M, Folini M, Zaffaroni N. Targeting survivin in cancer therapy: fulfilled promises and open questions. Carcinogenesis. 2007;28(6):1133\u20139.","journal-title":"Carcinogenesis"},{"issue":"2","key":"584_CR9","first-page":"342","volume":"60","author":"CP Webb","year":"2000","unstructured":"Webb CP, Hose CD, Koochekpour S, Jeffers M, Oskarsson M, Sausville E, Monks A, Vande Woude GF. The geldanamycins are potent inhibitors of the hepatocyte growth factor\/scatter factor-met-urokinase plasminogen activator\u2013plasmin proteolytic network. Cancer Res. 2000;60(2):342\u20139.","journal-title":"Cancer Res"},{"issue":"7","key":"584_CR10","doi-asserted-by":"crossref","first-page":"3346","DOI":"10.1210\/jc.2002-020340","volume":"88","author":"JW Park","year":"2003","unstructured":"Park JW, Yeh MW, Wong MG, Lobo M, Hyun WC, Duh QY, Clark OH. The heat shock protein 90-binding geldanamycin inhibits cancer cell proliferation, down-regulates oncoproteins, and inhibits epidermal growth factor-induced invasion in thyroid cancer cell lines. J Clin Endocrinol Metab. 2003;88(7):3346\u201353.","journal-title":"J Clin Endocrinol Metab"},{"issue":"6709","key":"584_CR11","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1038\/24550","volume":"396","author":"SL Rutherford","year":"1998","unstructured":"Rutherford SL, Lindquist S. Hsp90 as a capacitor for morphological evolution. Nature. 1998;396(6709):336\u201342.","journal-title":"Nature"},{"issue":"2","key":"584_CR12","doi-asserted-by":"crossref","first-page":"260","DOI":"10.3171\/jns.1985.63.2.0260","volume":"63","author":"A Kato","year":"1985","unstructured":"Kato A, Ushio Y, Hayakawa T, Yamada K, Ikeda H, Mogami H. Circulatory disturbance of the spinal cord with epidural neoplasm in rats. J Neurosurg. 1985;63(2):260\u20135.","journal-title":"J Neurosurg"},{"issue":"6","key":"584_CR13","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/j.spinee.2004.06.006","volume":"4","author":"M Takahashi","year":"2004","unstructured":"Takahashi M, Ogawa J, Kinoshita Y, Takakura M, Mochizuki K, Satomi K. Experimental study of paraplegia caused by spinal tumors: an animal model of spinal tumors created by transplantation of VX2 carcinoma. Spine J. 2004;4(6):675\u201380.","journal-title":"Spine J"},{"issue":"2","key":"584_CR14","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1227\/01.NEU.0000166683.67906.B7","volume":"57","author":"E Amundson","year":"2005","unstructured":"Amundson E, Pradilla G, Brastianos P, Bagley C, Riley 3rd LH, Garonzik IM, McCarthy E, Wolinsky JP, Gokaslan ZL. A novel intravertebral tumor model in rabbits. Neurosurgery. 2005;57(2):341\u20136. discussion 341\u2013346.","journal-title":"Neurosurgery"},{"issue":"23","key":"584_CR15","first-page":"6876","volume":"48","author":"F Arguello","year":"1988","unstructured":"Arguello F, Baggs RB, Frantz CN. A murine model of experimental metastasis to bone and bone marrow. Cancer Res. 1988;48(23):6876\u201381.","journal-title":"Cancer Res"},{"issue":"8","key":"584_CR16","first-page":"2304","volume":"52","author":"F Arguello","year":"1992","unstructured":"Arguello F, Furlanetto RW, Baggs RB, Graves BT, Harwell SE, Cohen HJ, Frantz CN. Incidence and distribution of experimental metastases in mutant mice with defective organ microenvironments (genotypes Sl\/Sld and W\/Wv). Cancer Res. 1992;52(8):2304\u20139.","journal-title":"Cancer Res"},{"key":"584_CR17","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1038\/bjc.2012.188","volume":"107","author":"B Gibert","year":"2012","unstructured":"Gibert B, Eckel B, Gonin V, Goldschneider D, Fombonne J, Deux B, Mehlen P, Arrigo A, Cl\u00e9zardin P, Diaz-Latoud C. Targeting heat shock protein 27 (HspB1) interferes with bone metastasis and tumour formation in vivo. Br J Cancer. 2012;107:63\u201370.","journal-title":"Br J Cancer"},{"key":"584_CR18","doi-asserted-by":"crossref","unstructured":"Zhao Z, Cheng CF, Kim R, Chen M, Woodley D, Li W: Targeting secreted heat shock protein-90alpha (Hsp90\u03b1) to prevent breast cancer progression. In: 2010: BioMed Central Ltd; 2010: O14.","DOI":"10.1186\/1753-6561-4-S2-O14"},{"issue":"4","key":"584_CR19","doi-asserted-by":"crossref","first-page":"e18848","DOI":"10.1371\/journal.pone.0018848","volume":"6","author":"JD Sims","year":"2011","unstructured":"Sims JD, McCready J, Jay DG. Extracellular heat shock protein (Hsp) 70 and Hsp90\u03b1 assist in matrix metalloproteinase-2 activation and breast cancer cell migration and invasion. PLoS One. 2011;6(4):e18848.","journal-title":"PLoS One"},{"issue":"3","key":"584_CR20","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/S1535-6108(03)00029-1","volume":"3","author":"JS Isaacs","year":"2003","unstructured":"Isaacs JS, Xu W, Neckers L. Heat shock protein 90 as a molecular target for cancer therapeutics. Cancer Cell. 2003;3(3):213\u20137.","journal-title":"Cancer Cell"},{"issue":"3","key":"584_CR21","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1007\/s12038-007-0051-y","volume":"32","author":"L Neckers","year":"2007","unstructured":"Neckers L. Heat shock protein 90: the cancer chaperone. J Biosci. 2007;32(3):517\u201330.","journal-title":"J Biosci"}],"container-title":["Tumor Biology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s13277-012-0584-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s13277-012-0584-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s13277-012-0584-z","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,10]],"date-time":"2019-07-10T05:49:34Z","timestamp":1562737774000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s13277-012-0584-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3,1]]},"references-count":21,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,6]]}},"alternative-id":["584"],"URL":"https:\/\/doi.org\/10.1007\/s13277-012-0584-z","relation":{},"ISSN":["1010-4283","1423-0380"],"issn-type":[{"value":"1010-4283","type":"print"},{"value":"1423-0380","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,3,1]]}}}