{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T09:32:09Z","timestamp":1789205529919,"version":"build-2803163510"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2013,8,9]],"date-time":"2013-08-09T00:00:00Z","timestamp":1376006400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tumor Biol."],"published-print":{"date-parts":[[2013,12]]},"DOI":"10.1007\/s13277-013-0986-6","type":"journal-article","created":{"date-parts":[[2013,8,8]],"date-time":"2013-08-08T03:22:11Z","timestamp":1375932131000},"page":"3981-3987","source":"Crossref","is-referenced-by-count":28,"title":["Elevated expression of hyaluronic acid binding protein 1 (HABP1)\/P32\/C1QBP is a novel indicator for lymph node and peritoneal metastasis of epithelial ovarian cancer patients"],"prefix":"10.1007","volume":"34","author":[{"given":"Hongyang","family":"Yu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Xin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lina","family":"Xing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guanglu","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiuying","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanju","family":"Lv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaowei","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chong","family":"Teng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dayong","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanju","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weixi","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chong","family":"Teng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yinghua","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fubin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,8,9]]},"reference":[{"key":"986_CR1","doi-asserted-by":"crossref","first-page":"11","DOI":"10.3322\/caac.21166","volume":"63","author":"R Siegel","year":"2013","unstructured":"Siegel R, Naishadham D, Jemal A. Cancer statistics, 2013. CA Cancer J Clin. 2013;63:11\u201330.","journal-title":"CA Cancer J Clin"},{"key":"986_CR2","doi-asserted-by":"crossref","first-page":"2519","DOI":"10.1056\/NEJMra041842","volume":"351","author":"SA Cannistra","year":"2004","unstructured":"Cannistra SA. Cancer of the ovary. N Engl J Med. 2004;351:2519\u201329.","journal-title":"N Engl J Med"},{"key":"986_CR3","first-page":"g8","volume":"2","author":"D Amadori","year":"1997","unstructured":"Amadori D, Sansoni E, Amadori A. Ovarian cancer: natural history and metastatic pattern. Front Biosci. 1997;2:g8\u2013g10.","journal-title":"Front Biosci"},{"key":"986_CR4","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/S1535-6108(04)00002-9","volume":"5","author":"RF Ozols","year":"2004","unstructured":"Ozols RF, Bookman MA, Connolly DC, et al. Focus on epithelial ovarian cancer. Cancer Cell. 2004;5:19\u201324.","journal-title":"Cancer Cell"},{"key":"986_CR5","doi-asserted-by":"crossref","first-page":"102","DOI":"10.4251\/wjgo.v2.i2.102","volume":"5","author":"A Fagotti","year":"2010","unstructured":"Fagotti A, Gallotta V, Romano F, et al. Peritoneal carcinosis of ovarian origin. World J Gastrointest Oncol. 2010;5:102\u20138.","journal-title":"World J Gastrointest Oncol"},{"key":"986_CR6","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.ygyno.2008.08.033","volume":"112","author":"RE Bristow","year":"2009","unstructured":"Bristow RE, Puri I, Chi DS. Cytoreductive surgery for recurrent ovarian cancer: a meta-analysis. Gynecol Oncol. 2009;112:265\u201374.","journal-title":"Gynecol Oncol"},{"key":"986_CR7","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1007\/s13277-012-0389-0","volume":"33","author":"I Mitrus","year":"2012","unstructured":"Mitrus I, Bryndza E, Sochanik A, Szala S. Evolving models of tumor origin and progression. Tumour Biol. 2012;33:911\u20137.","journal-title":"Tumour Biol"},{"key":"986_CR8","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1055\/s-2006-948556","volume":"24","author":"C Ricciardelli","year":"2006","unstructured":"Ricciardelli C. Extracellular matrix of ovarian tumors. Semin Reprod Med. 2006;24:270\u201382.","journal-title":"Semin Reprod Med"},{"key":"986_CR9","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1038\/35077241","volume":"411","author":"LA Liotta","year":"2001","unstructured":"Liotta LA, Kohn EC. The microenvironment of the tumour-host interface. Nature. 2001;411:375\u20139.","journal-title":"Nature"},{"key":"986_CR10","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1007\/BF00123391","volume":"14","author":"MJ Gardner","year":"1996","unstructured":"Gardner MJ, Catterall JB, Jones LM, et al. Human ovarian tumour cells can bind hyaluronic acid via membrane CD44: a possible step in peritoneal metastasis. Clin Exp Metastasis. 1996;14:325\u201334.","journal-title":"Clin Exp Metastasis"},{"key":"986_CR11","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1007\/BF00121913","volume":"13","author":"LM Jones","year":"1995","unstructured":"Jones LM, Gardner MJ, Catterall JB, et al. Hyaluronic acid secreted by mesothelial cells: a natural barrier to ovarian cancer cell adhesion. Clin Exp Metastasis. 1995;13:373\u201380.","journal-title":"Clin Exp Metastasis"},{"key":"986_CR12","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1593\/neo.91272","volume":"12","author":"YC Tzuman","year":"2010","unstructured":"Tzuman YC, Sapoznik S, Granot D, et al. Peritoneal adhesion and angiogenesis in ovarian carcinoma are inversely regulated by hyaluronan: the role of gonadotropins. Neoplasia. 2010;12:51\u201360.","journal-title":"Neoplasia"},{"key":"986_CR13","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/s10585-010-9363-7","volume":"28","author":"MP Ween","year":"2011","unstructured":"Ween MP, Hummitzsch K, Rodgers RJ, et al. Versican induces a pro-metastatic ovarian cancer cell behavior which can be inhibited by small hyaluronan oligosaccharides. Clin Exp Metastasis. 2011;28:113\u201325.","journal-title":"Clin Exp Metastasis"},{"key":"986_CR14","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1023\/A:1024009131191","volume":"20","author":"RC Casey","year":"2003","unstructured":"Casey RC, Koch KA, Oegema Jr TR, et al. Establishment of an in vitro assay to measure the invasion of ovarian carcinoma cells through mesothelial cell monolayers. Clin Exp Metastasis. 2003;20:343\u201356.","journal-title":"Clin Exp Metastasis"},{"key":"986_CR15","doi-asserted-by":"crossref","first-page":"3598","DOI":"10.1158\/1078-0432.CCR-07-2019","volume":"14","author":"A Banzato","year":"2008","unstructured":"Banzato A, Bobisse S, Rondina M, et al. A paclitaxel-hyaluronan bioconjugate targeting ovarian cancer affords a potent in vivo therapeutic activity. Clin Cancer Res. 2008;14:3598\u2013606.","journal-title":"Clin Cancer Res"},{"key":"986_CR16","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1006\/geno.1998.5364","volume":"51","author":"M Majumdar","year":"1998","unstructured":"Majumdar M, Datta K. Assignment of cDNA encoding hyaluronic acid-binding protein 1 to human chromosome 17p12\u2013p13. Genomics. 1998;51:476\u20137.","journal-title":"Genomics"},{"key":"986_CR17","doi-asserted-by":"crossref","first-page":"2206","DOI":"10.1074\/jbc.271.4.2206","volume":"271","author":"TB Deb","year":"1996","unstructured":"Deb TB, Datta K. Molecular cloning of human fibroblast hyaluronic acid-binding protein confirms its identity with P-32. A protein co-purified with splicing factor SF2. J Biol Chem. 1996;271:2206\u201312.","journal-title":"J Biol Chem"},{"key":"986_CR18","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/0092-8674(91)90627-B","volume":"66","author":"AR Krainer","year":"1991","unstructured":"Krainer AR, Mayeda A, Kozak D, et al. Functional expression of cloned human splicing factor SF2: homology to RNA-binding proteins. U170K and Drosophila splicing regulators. Cell. 1991;66:383\u201394.","journal-title":"Cell"},{"key":"986_CR19","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/0014-4827(91)90388-B","volume":"195","author":"S Gupta","year":"1991","unstructured":"Gupta S, Datta K. Possible role of hyaluronectin on cell adhesion in rat histiocytoma. Exp Cell Res. 1991;195:386\u201394.","journal-title":"Exp Cell Res"},{"key":"986_CR20","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1002\/mrd.1080380112","volume":"38","author":"S Ranganathan","year":"1994","unstructured":"Ranganathan S, Ganguly AK, Datta K. Evidence for presence of hyaluronan binding protein on spermatozoa and its possible involvement in sperm function. Mol Reprod Dev. 1994;38:69\u201376.","journal-title":"Mol Reprod Dev"},{"key":"986_CR21","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S0378-1119(97)00035-8","volume":"190","author":"S Das","year":"1997","unstructured":"Das S, Deb TB, Kumar R, et al. Multifunctional activities of human fibroblast 34-kDa hyaluronic acid-binding protein. Gene. 1997;190:223\u20135.","journal-title":"Gene"},{"key":"986_CR22","first-page":"58","volume":"56","author":"S Gupta","year":"1991","unstructured":"Gupta S, Batchu RB, Datta K. Purification partial characterization of rat kidney hyaluronic acid binding protein and its localization on the cell surface. Eur J Cell Biol. 1991;56:58\u201367.","journal-title":"Eur J Cell Biol"},{"key":"986_CR23","first-page":"327","volume":"40","author":"CM Rao","year":"1996","unstructured":"Rao CM, Deb TB, Datta K. Hyaluronic acid induced hyaluronic acid binding protein phosphorylation and inositol triphosphate formation in lymphocytes. Biochem Mol Biol Int. 1996;40:327\u201337.","journal-title":"Biochem Mol Biol Int"},{"key":"986_CR24","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/S0304-4165(97)00049-4","volume":"1336","author":"CM Rao","year":"1997","unstructured":"Rao CM, Deb TB, Gupta S, et al. Regulation of cellular phosphorylation of hyaluronan binding protein and its role in the formation of second messenger. Biochim Biophys Acta. 1997;1336:387\u201393.","journal-title":"Biochim Biophys Acta"},{"key":"986_CR25","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1016\/j.ccr.2008.04.002","volume":"13","author":"K Itahana","year":"2008","unstructured":"Itahana K, Zhang Y. Mitochondrial p32 is a critical mediator of ARF-induced apoptosis. Cancer Cell. 2008;13:542\u201353.","journal-title":"Cancer Cell"},{"key":"986_CR26","doi-asserted-by":"crossref","first-page":"6677","DOI":"10.1038\/sj.onc.1210485","volume":"26","author":"S Reef","year":"2007","unstructured":"Reef S, Shifman O, Oren M, et al. The autophagic inducer smARF interacts with and is stabilized by the mitochondrial p32 protein. Oncogene. 2007;26:6677\u201383.","journal-title":"Oncogene"},{"key":"986_CR27","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1016\/j.carbpol.2012.06.058","volume":"90","author":"T Xin","year":"2012","unstructured":"Xin T, Zhang F, Jiang Q, Chen C, Huang D, Li Y, et al. Extraction, purification and antitumor activity of a water-soluble polysaccharide from the roots of Polygala tenuifolia. Carbohydr Polym. 2012;90:1127\u201331.","journal-title":"Carbohydr Polym"},{"key":"986_CR28","doi-asserted-by":"crossref","first-page":"23093","DOI":"10.1074\/jbc.M111.233304","volume":"286","author":"HJ Yoo","year":"2011","unstructured":"Yoo HJ, Lee JS, Ko YG. Cell-surface gC1qR is a key regulator for lamellipodia formation and cancer metastasis. J Biol Chem. 2011;286:23093\u2013101.","journal-title":"J Biol Chem"},{"key":"986_CR29","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1111\/j.1349-7006.2010.01828.x","volume":"102","author":"R Amamoto","year":"2011","unstructured":"Amamoto R, Yagi M, Song Y, et al. Mitochondrial p32\/C1QBP is highly expressed in prostate cancer and is associated with shorter prostate-specific antigen relapse time after radical prostatectomy. Cancer Sci. 2011;102:639\u201347.","journal-title":"Cancer Sci"},{"key":"986_CR30","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1023\/B:MCBI.0000049362.04033.ea","volume":"267","author":"I Ghosh","year":"2004","unstructured":"Ghosh I, Chowdhury AR, Rajeswari MR, et al. Differential expression of hyaluronic acid binding protein 1 (HABP1)\/P32\/C1QBP during progression of epidermal carcinoma. Mol Cell Biochem. 2004;267:133\u20139.","journal-title":"Mol Cell Biochem"},{"key":"986_CR31","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.1016\/j.cellsig.2011.04.009","volume":"23","author":"M Prakash","year":"2011","unstructured":"Prakash M, Kale S, Ghosh I, Kundu GC, Datta K. Hyaluronan-binding protein 1 (HABP1\/p32\/gC1qR) induces melanoma cell migration and tumor growth by NF-kappa B dependent MMP-2 activation through integrin \u03b1(v)\u03b2(3) interaction. Cell Signal. 2011;23:1563\u201377.","journal-title":"Cell Signal"},{"key":"986_CR32","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1002\/ijc.20105","volume":"110","author":"DB Rubinstein","year":"2004","unstructured":"Rubinstein DB, Stortchevoi A, Boosalis M, et al. Receptor for the globular heads of C1q (gC1q-R. p33. hyaluronan-binding protein) is preferentially expressed by adenocarcinoma cells. Int J Cancer. 2004;110:741\u201350.","journal-title":"Int J Cancer"},{"key":"986_CR33","doi-asserted-by":"crossref","first-page":"7210","DOI":"10.1158\/0008-5472.CAN-07-6752","volume":"68","author":"V Fogal","year":"2008","unstructured":"Fogal V, Zhang L, Krajewski S, et al. Mitochondrial\/cell-surface protein p32\/gC1qR as a molecular target in tumor cells and tumor stroma. Cancer Res. 2008;68:7210\u20138.","journal-title":"Cancer Res"},{"key":"986_CR34","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1007\/s10495-006-5396-4","volume":"11","author":"A Kamal","year":"2006","unstructured":"Kamal A, Datta K. Upregulation of hyaluronan binding protein 1 (HABP1\/p32\/gC1qR) is associated with cisplatin induced apoptosis. Apoptosis. 2006;11:861\u201374.","journal-title":"Apoptosis"},{"key":"986_CR35","doi-asserted-by":"crossref","DOI":"10.1007\/978-3-642-58564-7","volume-title":"Histological typing of ovarian tumors (WHO. World Health Organization. International Histological Classification of Tumours)","author":"R Scully","year":"1999","unstructured":"Scully R. Histological typing of ovarian tumors (WHO. World Health Organization. International Histological Classification of Tumours). Berlin: Springer; 1999."},{"key":"986_CR36","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/S0020-7292(00)90001-8","volume":"70","author":"JL Benedet","year":"2000","unstructured":"Benedet JL, Bender H, Jones H, et al. FIGO staging classifications and clinical practice guidelines in the management of gynecologic cancers. FIGO Committee on Gynecologic Oncology. Int J Gynaecol Obstet. 2000;70:209\u201362.","journal-title":"Int J Gynaecol Obstet"},{"key":"986_CR37","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.yexmp.2012.06.007","volume":"94","author":"G Yu","year":"2013","unstructured":"Yu G, Wang J. Significance of hyaluronan binding protein (HABP1\/P32\/gC1qR) expression in advanced serous ovarian cancer patients. Exp Mol Pathol. 2013;94:210\u20135.","journal-title":"Exp Mol Pathol"},{"key":"986_CR38","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1007\/s00418-006-0225-y","volume":"126","author":"S Kitazawa","year":"2006","unstructured":"Kitazawa S, Takenaka A, Kondo T, et al. Protruding disordered loop of gC1qR is specifically exposed and related to antiapoptotic property in germ cell lineage. Histochem Cell Biol. 2006;126:665\u201377.","journal-title":"Histochem Cell Biol"},{"key":"986_CR39","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1128\/MCB.01661-09","volume":"30","author":"CV Dang","year":"2010","unstructured":"Dang CV. p32 (C1QBP) and cancer cell metabolism: is the Warburg effect a lot of hot air? Mol Cell Biol. 2010;30:1300\u20132.","journal-title":"Mol Cell Biol"},{"key":"986_CR40","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1038\/sj.cr.7290284","volume":"15","author":"A Sengupta","year":"2005","unstructured":"Sengupta A, Banerjee B, Tyagi RK, et al. Golgi localization and dynamics of hyaluronan binding protein 1 (HABP1\/p32\/C1QBP) during the cell cycle. Cell Res. 2005;15:183\u20136.","journal-title":"Cell Res"},{"key":"986_CR41","doi-asserted-by":"crossref","first-page":"24601","DOI":"10.1074\/jbc.M002964200","volume":"275","author":"P Storz","year":"2000","unstructured":"Storz P, Hausser A, Link G, et al. Protein kinase C is regulated by the multifunctional chaperon protein p32. J Biol Chem. 2000;275:24601\u20137.","journal-title":"J Biol Chem"},{"key":"986_CR42","doi-asserted-by":"crossref","first-page":"19750","DOI":"10.1074\/jbc.M111.266270","volume":"287","author":"R Kaul","year":"2012","unstructured":"Kaul R, Saha P, Saradhi M, Prasad RL, Chatterjee S, Ghosh I, et al. Overexpression of hyaluronan-binding protein 1 (HABP1\/p32\/gC1qR) in HepG2 cells leads to increased hyaluronan synthesis and cell proliferation by up-regulation of cyclin D1 in AKT-dependent pathway. J Biol Chem. 2012;287:19750\u201364.","journal-title":"J Biol Chem"}],"container-title":["Tumor Biology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s13277-013-0986-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s13277-013-0986-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s13277-013-0986-6","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,2]],"date-time":"2019-06-02T11:26:33Z","timestamp":1559474793000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s13277-013-0986-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,8,9]]},"references-count":42,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2013,12]]}},"alternative-id":["986"],"URL":"https:\/\/doi.org\/10.1007\/s13277-013-0986-6","relation":{},"ISSN":["1010-4283","1423-0380"],"issn-type":[{"value":"1010-4283","type":"print"},{"value":"1423-0380","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,8,9]]}}}