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Marissa Betts and Katarzyna Borkowska are employed by Evidera, which provides consulting and other research services to pharmaceutical, medical device, and related organizations. In their salaried positions, they work with a variety of companies and organizations and are precluded from receiving payment or honoraria directly from these organizations for services rendered. Mike Baxter is CEO\/MD of Endotech, a company providing private medical services to patients with diabetes and endocrine conditions. He is deputy Chairman of Frimley Health and is a non-executive member of the trusts board. He is also an honorary professor of medicine at the University of Swansea. In the past, he has been involved in consultative roles for a number of commercial organisations but is not currently receiving any payment from any agencies and did not receive any payment for his involvement in this project\/manuscript.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"Ethics committee approval was not required for this systematic review because it involved the synthesis and analysis of existing data from previously published studies. A systematic review does not involve direct contact with human subjects or the collection of new data. Therefore, obtaining ethics committee approval was deemed unnecessary for this study. This study was performed in accordance with the Helsinki Declaration of 1964 and its later amendments.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}}]}}