{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T08:36:52Z","timestamp":1790757412520,"version":"4.1.0"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2024,8,10]],"date-time":"2024-08-10T00:00:00Z","timestamp":1723248000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,8,10]],"date-time":"2024-08-10T00:00:00Z","timestamp":1723248000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100005047","name":"Natural Science Foundation of Liaoning Province","doi-asserted-by":"publisher","award":["20180550218"],"award-info":[{"award-number":["20180550218"]}],"id":[{"id":"10.13039\/501100005047","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Updates Surg"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>Traditional anesthesia for video-assisted thoracoscopy (VATS) such as double-lumen tracheal intubation (DLT) and one-lung ventilation (OLV), may lead to post-operative pulmonary complications (PPCs). Non-intubation VATS (NIVATS) is an anesthetic technique that avoided DLT and OLV, maybe avoiding the PPCs. So we hypothesized that NIVATS would non-inferiority to intubation VATS (IVATS) in the risk of developing PPCs and some safety indicators.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>This study is a randomised, controlled, double-blind, non-inferiority trial, 120 patients were randomly assigned to the NIVATS group and IVATS group according to 1:1. The primary outcome was the incidence of PPCs with a pre-defined non-inferiority margin of 10%. The second outcome was the safety indicators, including the incidence of cough\/body movement, hypoxemia, malignant arrhythmia, regurgitation and aspiration, and transferring to endobronchial intubation intraoperatively (The malignant arrhythmia was defined as an arrhythmia that caused hemodynamic disturbances in a short period of time, resulting in persistent hypotension or even cardiac arrest in the patient).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>There was no significant difference in demographic indicators such as gender and age between the two groups. The incidence of PPCs in the NIVATS group was non-inferior to that in the IVATS group (1.67% vs. 3.33%, absolute difference: \u2212\u00a01.67%; 95%CI \u2212\u00a07.25 to 3.91). In additionan, no significant differences were found between the two groups for the incidence of cough\/body movement (10.00% vs. 11.67%, <jats:italic>p<\/jats:italic>\u2009=\u20090.77), the incidence of hypoxemia (25% vs. 18.33%, <jats:italic>p<\/jats:italic>\u2009=\u20090.38), the incidence of malignant arrhythmia (1.67% vs. 6.67%, <jats:italic>p<\/jats:italic>\u2009=\u20090.36), the incidence of regurgitation and aspiration (0% vs. 0%, <jats:italic>p<\/jats:italic>\u2009&gt;\u20090.999) and the incidence of transferring to endobronchial intubation intraoperatively (0% vs. 0%, <jats:italic>p<\/jats:italic>\u2009&gt;\u20090.999).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>We conclude that when using the non-intubation anesthesia for VATS, the incidence of PPCs was not inferior to intubation anesthesia. Furthermore, NIVATS had little effect on perioperative safety.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s13304-024-01935-y","type":"journal-article","created":{"date-parts":[[2024,8,10]],"date-time":"2024-08-10T07:02:32Z","timestamp":1723273352000},"page":"2863-2873","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Comparison of postoperative pulmonary complications and intraoperative safety in thoracoscopic surgery under non-intubated versus intubated anesthesia: a randomized, controlled, double-blind non-inferiority trial"],"prefix":"10.1007","volume":"76","author":[{"given":"Lingfei","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanmei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,8,10]]},"reference":[{"key":"1935_CR1","doi-asserted-by":"publisher","first-page":"1011849","DOI":"10.3389\/fonc.2022.1011849","volume":"12","author":"W Liu","year":"2022","unstructured":"Liu W, Jin F, Wang HM, Yong FF, Wu Z, Jia HQ (2022) The association between double-lumen tube versus bronchial blocker and postoperative pulmonary complications in patients after lung cancer surgery. 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The study protocol was approved by the Liaoning Cancer Hospital & Institute (China) ethics committees (2020[05] No. 20200459). Written informed consent was obtained from all participants or their legal guardians.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}]}}