{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T02:07:19Z","timestamp":1789092439724,"version":"build-2803163510"},"reference-count":9,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,11,13]],"date-time":"2024-11-13T00:00:00Z","timestamp":1731456000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,11,13]],"date-time":"2024-11-13T00:00:00Z","timestamp":1731456000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100009104","name":"Universit\u00e0 degli Studi di Modena e Reggio Emilia","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100009104","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Updates Surg"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:p>Situs viscerum inversus totalis (SIT) is a rare congenital anomaly. Deceased donors with this condition are often declined because of the technical issues in both the organ\u2019s procurement and its transplant. Only eight cases of deceased donor organs with  SIT\u00a0were reported to be used for liver transplantation (LT). We herein present a case of LT using a graft from an SIT donor: a modified retroversus piggyback technique was used. A 15\u00a0year-old female was referred to our institution as a potential donor. An SIT condition was discovered during standard donor evaluation together with the presence of a complex triple arterial pedicle. Procurement operative time was 125\u00a0min, from skin incision to cross-clamp. Liver extraction occurred 32\u00a0min after cold flush. The recipient was a 56\u00a0year-old male affected by recurrent hepatocellular carcinoma (HCC) on hepatitis C related liver cirrhosis. Position and orientation trials of the graft were made and it was decided to implant it with the retroversus technique. Direct duct-to-duct biliary reconstruction was achieved. The postoperative course was uneventful. To our knowledge, this is the first implant with retroversus technique combined to direct biliary reconstruction and the first repetition of that technique. Cases like this highlight how technical complexity can be overcome leading to successful management of difficult scenarios in a safe manner.<\/jats:p>","DOI":"10.1007\/s13304-024-01968-3","type":"journal-article","created":{"date-parts":[[2024,11,13]],"date-time":"2024-11-13T09:02:20Z","timestamp":1731488540000},"page":"77-82","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Matching the opposites: liver transplantation from a situs viscerum inversus totalis donor"],"prefix":"10.1007","volume":"77","author":[{"given":"Cristiano","family":"Guidetti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberta","family":"Odorizzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Catellani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip","family":"Muller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Magistri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gian Piero","family":"Guerrini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Di Sandro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6718-8760","authenticated-orcid":false,"given":"Fabrizio","family":"Di Benedetto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,11,13]]},"reference":[{"issue":"4","key":"1968_CR1","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1002\/ajmg.1219","volume":"101","author":"AS Aylsworth","year":"2001","unstructured":"Aylsworth AS (2001) Clinical aspects of defects in the determination of laterality. Am J Med Genet 101(4):345\u2013355","journal-title":"Am J Med Genet"},{"key":"1968_CR2","doi-asserted-by":"publisher","first-page":"2437","DOI":"10.2147\/IJGM.S295444","volume":"15","author":"K Eitler","year":"2022","unstructured":"Eitler K, Bibok A, Telkes G (2022) Situs inversus totalis: a clinical review. Int J Gen Med 15:2437\u20132449. https:\/\/doi.org\/10.2147\/IJGM.S295444","journal-title":"Int J Gen Med"},{"issue":"3","key":"1968_CR3","doi-asserted-by":"publisher","first-page":"1002","DOI":"10.1016\/j.athoracsur.2009.01.060","volume":"88","author":"T Deuse","year":"2009","unstructured":"Deuse T, Reitz BA (2009) Heart-lung transplantation in situs inversus totalis. Ann Thorac Surg 88(3):1002\u20131003. https:\/\/doi.org\/10.1016\/j.athoracsur.2009.01.060","journal-title":"Ann Thorac Surg"},{"issue":"1","key":"1968_CR4","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1097\/00007890-199607150-00027","volume":"62","author":"LA Herrera","year":"1996","unstructured":"Herrera LA, Castillo J, Martino E, Rabanal JM, Fleitas MG (1996) Orthotopic liver transplantation from a donor with abdominal situs inversus. Transplantation 62(1):133\u2013135. https:\/\/doi.org\/10.1097\/00007890-199607150-00027","journal-title":"Transplantation"},{"issue":"7","key":"1968_CR5","doi-asserted-by":"publisher","first-page":"1869","DOI":"10.1111\/j.1600-6143.2007.01843.x","volume":"7","author":"JJ Pomposelli","year":"2007","unstructured":"Pomposelli JJ, DaCosta MA, McPartland K, Jenkins RL (2007) Retroversus implantation of a liver graft: a novel approach to the deceased donor with situs inversus totalis. Am J Transplant 7(7):1869\u20131871. https:\/\/doi.org\/10.1111\/j.1600-6143.2007.01843.x","journal-title":"Am J Transplant"},{"issue":"2","key":"1968_CR6","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1016\/j.transproceed.2018.12.002","volume":"51","author":"S Reimondez","year":"2019","unstructured":"Reimondez S, Alcaraz \u00c1, Giordano Segade E, Ag\u00fceroRamaccioni N, CasarezD\u00edaz G, Maraschio MA (2019) Liver transplant from a donor with situs inversus totalis using orthotopic and retroversus technique: a case report. Transplant Proc 51(2):585\u2013588. https:\/\/doi.org\/10.1016\/j.transproceed.2018.12.002","journal-title":"Transplant Proc"},{"key":"1968_CR7","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1016\/j.ijscr.2014.10.037","volume":"6","author":"TM Manzia","year":"2015","unstructured":"Manzia TM, Tariciotti L, Angelico R, Toti L, Anselmo A, Tisone G (2015) Side-to-side caval anastomosis in a patient receiving a liver graft from a marginal donor with situs inversus totalis. Int J Surg Case Rep 6:222\u2013225. https:\/\/doi.org\/10.1016\/j.ijscr.2014.10.037","journal-title":"Int J Surg Case Rep"},{"issue":"10","key":"1968_CR8","doi-asserted-by":"publisher","first-page":"e88","DOI":"10.1111\/tri.12136","volume":"26","author":"DB Moon","year":"2013","unstructured":"Moon DB, Lee SG, Ha TY (2013) Novel technique of implantation for reversed modified right lobe graft from a donor with situs inversus totalis: new challenge in adult living donor liver transplantation. Transpl Int 26(10):e88\u2013e90. https:\/\/doi.org\/10.1111\/tri.12136","journal-title":"Transpl Int"},{"issue":"2","key":"1968_CR9","doi-asserted-by":"publisher","first-page":"617","DOI":"10.1016\/j.surg.2021.04.015","volume":"170","author":"D Balci","year":"2021","unstructured":"Balci D, Bingol-Kologlu M, Kirimker EO et al (2021) 3D-reconstruction and heterotopic implantation of reduced size monosegment or left lateral segment grafts in small infants: A new technique in pediatric living donor liver transplantation to overcome large-for-size syndrome. Surgery 170(2):617\u2013622. https:\/\/doi.org\/10.1016\/j.surg.2021.04.015","journal-title":"Surgery"}],"container-title":["Updates in Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13304-024-01968-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s13304-024-01968-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13304-024-01968-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T15:43:51Z","timestamp":1741016631000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s13304-024-01968-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,13]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["1968"],"URL":"https:\/\/doi.org\/10.1007\/s13304-024-01968-3","relation":{},"ISSN":["2038-131X","2038-3312"],"issn-type":[{"value":"2038-131X","type":"print"},{"value":"2038-3312","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,13]]},"assertion":[{"value":"25 February 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 August 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 November 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval and Research involving human participants and\/or animals"}},{"value":"Informed consent was obtained by the patient for the described procedure.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}