{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T16:26:22Z","timestamp":1780763182734,"version":"3.54.1"},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2025,1,30]],"date-time":"2025-01-30T00:00:00Z","timestamp":1738195200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,1,30]],"date-time":"2025-01-30T00:00:00Z","timestamp":1738195200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100008375","name":"University of Basel","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100008375","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Updates Surg"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background<\/jats:title>\n            <jats:p>Primary hyperparathyroidism (PHPT) due to a parathyroid adenoma stands as one of the most prevalent endocrinological disorders, with focused parathyroidectomy being the established therapeutic strategy.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Aim<\/jats:title>\n            <jats:p>This study aims to investigate whether the volume of the pathological gland influences perioperative outcomes and postoperative morbidity.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>A retrospective analysis was conducted on data from 141 patients who underwent focused parathyroidectomy for PHPT at the University Hospital of Basel between 2007 and 2022.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>A total of 141 patients underwent surgery, with a mean age of 57.2\u00a0years and prevalence of women (64.5%).The volume of the lesion was divided into three groups (low\u2009&lt;\u20091\u00a0ml, middle 1\u20131.99\u00a0ml, large\u2009&gt;\u20092\u00a0ml) based on pathological specimen analysis. Preoperative calcium and parathyroid hormone (PTH) values were significantly higher in the large volume group compared to the low volume group (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05), while phosphate and vitamin D values were significantly lower (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). A comparison of adenoma volume in symptomatic patients with asymptomatic patients revealed no statistically significant difference (<jats:italic>p<\/jats:italic>\u2009=\u20090.845) and the volume of the gland of any group did not influence the length of the operation (<jats:italic>p<\/jats:italic>\u2009=\u20090.173) and the perioperative morbidity (<jats:italic>p<\/jats:italic>\u2009=\u20090.108).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>Compared to a volume of less than 1\u00a0ml, a parathyroid gland volume greater than 2\u00a0ml was associated with higher preoperative PTH and calcium levels and lower phosphate and vitamin D levels. The volume of the parathyroid gland does not seem to impact the clinical manifestations, or the incidence of perioperative complications.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s13304-025-02086-4","type":"journal-article","created":{"date-parts":[[2025,1,30]],"date-time":"2025-01-30T15:29:18Z","timestamp":1738250958000},"page":"381-388","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Correlation between parathyroid adenoma volume and perioperative outcomes in\u00a0primary hyperparathyroidism: Does the size matter?"],"prefix":"10.1007","volume":"77","author":[{"given":"Antonio","family":"Fiore","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Eschlb\u00f6ck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9line","family":"Carlen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ioannis I.","family":"Lazaridis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandros","family":"Lalos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raoul","family":"Droeser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tarik","family":"Delko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Posabella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,1,30]]},"reference":[{"issue":"2","key":"2086_CR1","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1038\/nrendo.2017.104","volume":"14","author":"MD Walker","year":"2018","unstructured":"Walker MD, Silverberg SJ (2018) Primary hyperparathyroidism. Nat Rev Endocrinol 14(2):115\u2013125. https:\/\/doi.org\/10.1038\/nrendo.2017.104","journal-title":"Nat Rev Endocrinol"},{"issue":"5","key":"2086_CR2","doi-asserted-by":"publisher","first-page":"689","DOI":"10.20945\/2359-3997000000558","volume":"66","author":"F Bandeira","year":"2022","unstructured":"Bandeira F, de Moura NJ, de Oliveira LB, Bilezikian J (2022) Medical management of primary hyperparathyroidism. Arch Endocrinol Metab 66(5):689\u2013693. https:\/\/doi.org\/10.20945\/2359-3997000000558","journal-title":"Arch Endocrinol Metab"},{"issue":"10","key":"2086_CR3","doi-asserted-by":"publisher","first-page":"771","DOI":"10.1136\/jclinpath-2015-203186","volume":"68","author":"K Duan","year":"2015","unstructured":"Duan K, Gomez Hernandez K, Mete O (2015) Clinicopathological correlates of hyperparathyroidism. J Clin Pathol 68(10):771\u2013787. https:\/\/doi.org\/10.1136\/jclinpath-2015-203186","journal-title":"J Clin Pathol"},{"issue":"1","key":"2086_CR4","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1016\/j.jocd.2012.11.005","volume":"16","author":"SJ Silverberg","year":"2013","unstructured":"Silverberg SJ, Walker MD, Bilezikian JP (2013) Asymptomatic primary hyperparathyroidism. J Clin Densitom 16(1):14\u201321. https:\/\/doi.org\/10.1016\/j.jocd.2012.11.005","journal-title":"J Clin Densitom"},{"issue":"11","key":"2086_CR5","doi-asserted-by":"publisher","first-page":"2293","DOI":"10.1002\/jbmr.4677","volume":"37","author":"JP Bilezikian","year":"2022","unstructured":"Bilezikian JP, Khan AA, Silverberg SJ et al (2022) Evaluation and management of primary hyperparathyroidism: summary statement and guidelines from the fifth international workshop. J Bone Miner Res 37(11):2293\u20132314. https:\/\/doi.org\/10.1002\/jbmr.4677","journal-title":"J Bone Miner Res"},{"issue":"2","key":"2086_CR6","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1590\/s0004-27302010000200004","volume":"54","author":"JP Bilezikian","year":"2010","unstructured":"Bilezikian JP, Silverberg SJ (2010) Normocalcemic primary hyperparathyroidism. Arq Bras Endocrinol Metabol 54(2):106\u2013109. https:\/\/doi.org\/10.1590\/s0004-27302010000200004","journal-title":"Arq Bras Endocrinol Metabol"},{"issue":"12","key":"2086_CR7","doi-asserted-by":"crossref","first-page":"1869","DOI":"10.1359\/jbmr.081018","volume":"23","author":"C Marcocci","year":"2008","unstructured":"Marcocci C, Cetani F, Rubin MR, Silverberg SJ, Pinchera A, Bilezikian JP (2008) Parathyroid carcinoma. J Bone Miner Res 23(12):1869\u20131880","journal-title":"J Bone Miner Res"},{"key":"2086_CR8","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/251410","volume":"2011","author":"J Mackenzie-Feder","year":"2011","unstructured":"Mackenzie-Feder J, Sirrs S, Anderson D, Sharif J, Khan A (2011) Primary hyperparathyroidism: an overview. Int J Endocrinol 2011:251410. https:\/\/doi.org\/10.1155\/2011\/251410","journal-title":"Int J Endocrinol"},{"issue":"4","key":"2086_CR9","doi-asserted-by":"publisher","first-page":"256","DOI":"10.5114\/reum\/170705","volume":"61","author":"M Kochman","year":"2023","unstructured":"Kochman M (2023) Primary hyperparathyroidism: clinical manifestations, diagnosis and evaluation according to the Fifth International Workshop guidelines. Reumatologia 61(4):256\u2013263. https:\/\/doi.org\/10.5114\/reum\/170705","journal-title":"Reumatologia"},{"issue":"5","key":"2086_CR10","doi-asserted-by":"publisher","first-page":"704","DOI":"10.1097\/01.sla.0000124448.49794.74","volume":"239","author":"GL Irvin 3rd","year":"2004","unstructured":"Irvin GL 3rd, Carneiro DM, Solorzano CC (2004) Progress in the operative management of sporadic primary hyperparathyroidism over 34 years. Ann Surg 239(5):704\u2013711. https:\/\/doi.org\/10.1097\/01.sla.0000124448.49794.74","journal-title":"Ann Surg"},{"issue":"3","key":"2086_CR11","doi-asserted-by":"publisher","first-page":"97","DOI":"10.4174\/astr.2016.91.3.97","volume":"91","author":"WW Kim","year":"2016","unstructured":"Kim WW, Rhee Y, Ban EJ et al (2016) Is focused parathyroidectomy appropriate for patients with primary hyperparathyroidism? Ann Surg Treat Res 91(3):97\u2013103. https:\/\/doi.org\/10.4174\/astr.2016.91.3.97","journal-title":"Ann Surg Treat Res"},{"key":"2086_CR12","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.ijsu.2015.11.045","volume":"25","author":"F Medas","year":"2016","unstructured":"Medas F et al (2016) Retrospective evaluation of the pre- and postoperative factors influencing the sensitivity of localization studies in primary hyperparathyroidism. Int J Surg 25:82\u201387","journal-title":"Int J Surg"},{"issue":"2","key":"2086_CR13","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1007\/s13304-015-0342-z","volume":"68","author":"PG Cal\u00f2","year":"2016","unstructured":"Cal\u00f2 PG et al (2016) Feasibility of unilateral parathyroidectomy in patients with primary hyperparathyroidism and negative or discordant localization studies. Updates Surg 68(2):155\u2013161","journal-title":"Updates Surg"},{"issue":"10","key":"2086_CR14","doi-asserted-by":"publisher","first-page":"959","DOI":"10.1001\/jamasurg.2016.2310","volume":"151","author":"SM Wilhelm","year":"2016","unstructured":"Wilhelm SM, Wang TS, Ruan DT et al (2016) The American association of endocrine surgeons guidelines for definitive management of primary hyperparathyroidism. JAMA Surg 151(10):959\u2013968. https:\/\/doi.org\/10.1001\/jamasurg.2016.2310","journal-title":"JAMA Surg"},{"issue":"5","key":"2086_CR15","doi-asserted-by":"publisher","first-page":"744","DOI":"10.3803\/EnM.2022.1589","volume":"37","author":"HS Park","year":"2022","unstructured":"Park HS, Hong N, Jeong JJ, Yun M, Rhee Y (2022) Update on preoperative parathyroid localization in primary hyperparathyroidism. Endocrinol Metab (Seoul) 37(5):744\u2013755. https:\/\/doi.org\/10.3803\/EnM.2022.1589","journal-title":"Endocrinol Metab (Seoul)"},{"issue":"9","key":"2086_CR16","doi-asserted-by":"publisher","first-page":"2801","DOI":"10.1007\/s00259-021-05334-y","volume":"48","author":"P Petranovi\u0107 Ov\u010dari\u010dek","year":"2021","unstructured":"Petranovi\u0107 Ov\u010dari\u010dek P, Giovanella L, Carri\u00f3 Gasset I et al (2021) The EANM practice guidelines for parathyroid imaging. Eur J Nucl Med Mol Imaging 48(9):2801\u20132822. https:\/\/doi.org\/10.1007\/s00259-021-05334-y","journal-title":"Eur J Nucl Med Mol Imaging"},{"issue":"4","key":"2086_CR17","doi-asserted-by":"publisher","first-page":"714","DOI":"10.1016\/j.surg.2013.05.013","volume":"154","author":"PM Spanheimer","year":"2013","unstructured":"Spanheimer PM, Stoltze AJ, Howe JR, Sugg SL, Lal G, Weigel RJ (2013) Do giant parathyroid adenomas represent a distinct clinical entity? Surgery 154(4):714\u2013719. https:\/\/doi.org\/10.1016\/j.surg.2013.05.013","journal-title":"Surgery"},{"issue":"7","key":"2086_CR18","doi-asserted-by":"publisher","first-page":"759","DOI":"10.1016\/j.asjsur.2019.10.004","volume":"43","author":"DCW Leong","year":"2020","unstructured":"Leong DCW, Lo J, Nguyen H, Ryan S (2020) Can we predict expected adenoma weight preoperatively with reference to the correlation of preoperative biochemical tests with parathyroid adenoma weight? Asian J Surg 43(7):759\u2013764. https:\/\/doi.org\/10.1016\/j.asjsur.2019.10.004","journal-title":"Asian J Surg"},{"key":"2086_CR19","doi-asserted-by":"publisher","DOI":"10.1186\/s12893-020-00922-5","author":"M Papadakis","year":"2020","unstructured":"Papadakis M, Weyerbrock N, Zirngibl H, Dotzenrath C (2020) Correlation of perioperative biochemical variables with single adenoma weight in patients with primary hyperparathyroidism. BMC Surg. https:\/\/doi.org\/10.1186\/s12893-020-00922-5","journal-title":"BMC Surg"},{"key":"2086_CR20","doi-asserted-by":"publisher","DOI":"10.2478\/enr-2023-0002","author":"E Rezkallah","year":"2023","unstructured":"Rezkallah E, Elsaify A, Hanna R, Elsaify W (2023) Correlation between preoperative calcium and parathormone levels with parathyroid gland volume. Endocr Regul. https:\/\/doi.org\/10.2478\/enr-2023-0002","journal-title":"Endocr Regul"},{"issue":"4","key":"2086_CR21","doi-asserted-by":"publisher","first-page":"441","DOI":"10.4183\/aeb.2017.441","volume":"13","author":"A Gatu","year":"2017","unstructured":"Gatu A, Velicescu C, Grigorovici A et al (2017) The volume of solitary parathyroid adenoma is related to preoperative PTH and 25OH-D3, but not to calcium levels. Acta Endocrinol (Buchar) 13(4):441\u2013446. https:\/\/doi.org\/10.4183\/aeb.2017.441","journal-title":"Acta Endocrinol (Buchar)"},{"issue":"2","key":"2086_CR22","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1111\/coa.12761","volume":"42","author":"S Stern","year":"2017","unstructured":"Stern S, Mizrachi A, Strenov Y et al (2017) Parathyroid adenoma: a comprehensive biochemical and histological correlative study. Clin Otolaryngol 42(2):381\u2013386. https:\/\/doi.org\/10.1111\/coa.12761","journal-title":"Clin Otolaryngol"},{"issue":"3","key":"2086_CR23","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1111\/j.1365-2273.2007.01447.x","volume":"32","author":"PS Randhawa","year":"2007","unstructured":"Randhawa PS, Mace AD, Nouraei SA, Stearns MP (2007) Primary hyperparathyroidism: do perioperative biochemical variables correlate with parathyroid adenoma weight or volume? Clin Otolaryngol 32(3):179\u2013184. https:\/\/doi.org\/10.1111\/j.1365-2273.2007.01447.x","journal-title":"Clin Otolaryngol"},{"issue":"46","key":"2086_CR24","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000027530","volume":"100","author":"M Javadov","year":"2021","unstructured":"Javadov M, Karatay E, Ulusan K et al (2021) Number of cells in parathyroid tissue in primary hyperparathyroidism cases and its relationship with serum calcium value. Medicine (Baltimore) 100(46):e27530. https:\/\/doi.org\/10.1097\/MD.0000000000027530","journal-title":"Medicine (Baltimore)"},{"issue":"470","key":"2086_CR25","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1016\/j.mce.2017.10.001","volume":"15","author":"M Lu","year":"2018","unstructured":"Lu M, Kjellin H, Fotouhi O, Lee L, Nilsson IL, Haglund F, H\u00f6\u00f6g A, Lehti\u00f6 J, Larsson C (2018) Molecular profiles of oxyphilic and chief cell parathyroid adenoma. Mol Cell Endocrinol 15(470):84\u201395. https:\/\/doi.org\/10.1016\/j.mce.2017.10.001","journal-title":"Mol Cell Endocrinol"},{"issue":"2","key":"2086_CR26","doi-asserted-by":"publisher","first-page":"440","DOI":"10.1007\/s12020-012-9810-0","volume":"43","author":"S Varshney","year":"2013","unstructured":"Varshney S, Bhadada SK, Nahar U, Shah VN, Bhansali A, Behera A (2013) Chief cell and clear cell parathyroid adenoma do not influence clinical and biochemical expression of the sporadic primary hyperparathyroidism. Endocrine 43(2):440\u2013443. https:\/\/doi.org\/10.1007\/s12020-012-9810-0","journal-title":"Endocrine"},{"issue":"3","key":"2086_CR27","doi-asserted-by":"publisher","first-page":"40","DOI":"10.5604\/01.3001.0054.4440","volume":"96","author":"M Kaszczewska","year":"2024","unstructured":"Kaszczewska M, Chudzi\u0144ski W, Kaszczewska J et al (2024) Do large parathyroid adenomas increase the risk of severe hypercalcemia? Pol Przegl Chir 96(3):40\u201350. https:\/\/doi.org\/10.5604\/01.3001.0054.4440","journal-title":"Pol Przegl Chir"},{"key":"2086_CR28","doi-asserted-by":"publisher","DOI":"10.2478\/rjim-2023-0018","author":"E Gezer","year":"2023","unstructured":"Gezer E, Zekey \u00d6, Bayrak BY et al (2023) A significant association between parathyroid adenoma volume and bone mineral loss at distal forearm. Rom J Intern Med. https:\/\/doi.org\/10.2478\/rjim-2023-0018","journal-title":"Rom J Intern Med"},{"key":"2086_CR29","doi-asserted-by":"publisher","DOI":"10.1210\/clinem\/dgaa579","author":"Z Qu","year":"2020","unstructured":"Qu Z, Yang F, Hong J, Wang W, Yan S (2020) Parathyroid hormone and bone mineral density: a mendelian randomization study. J Clin Endocrinol Metab. https:\/\/doi.org\/10.1210\/clinem\/dgaa579","journal-title":"J Clin Endocrinol Metab"},{"issue":"5","key":"2086_CR30","doi-asserted-by":"publisher","first-page":"1029","DOI":"10.1002\/jbmr.1841.PMID:23225022;PMCID:PMC3631282","volume":"28","author":"EM Stein","year":"2013","unstructured":"Stein EM, Silva BC, Boutroy S, Zhou B, Wang J, Udesky J, Zhang C, McMahon DJ, Romano M, Dworakowski E, Costa AG, Cusano N, Irani D, Cremers S, Shane E, Guo XE, Bilezikian JP (2013) Primary hyperparathyroidism is associated with abnormal cortical and trabecular microstructure and reduced bone stiffness in postmenopausal women. J Bone Miner Res 28(5):1029\u20131040. https:\/\/doi.org\/10.1002\/jbmr.1841.PMID:23225022;PMCID:PMC3631282","journal-title":"J Bone Miner Res"},{"issue":"10","key":"2086_CR31","doi-asserted-by":"publisher","first-page":"1903","DOI":"10.1002\/jbmr.4657","volume":"37","author":"A Bobillier","year":"2022","unstructured":"Bobillier A, Wagner P, Whittier DE, Ecochard R, Boyd SK, Chapurlat R, Szulc P (2022) Association of vitamin D and parathyroid hormone status with the aging-related decline of bone microarchitecture in older men: the prospective structure of aging men\u2019s bones (STRAMBO) study. J Bone Miner Res 37(10):1903\u20131914. https:\/\/doi.org\/10.1002\/jbmr.4657. (Epub 2022 Aug 17 PMID: 35880628)","journal-title":"J Bone Miner Res"},{"issue":"3","key":"2086_CR32","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1002\/jbmr.4763","volume":"38","author":"K Lundstam","year":"2023","unstructured":"Lundstam K, Pretorius M, Bollerslev J, Godang K, Fagerland MW, Mollerup C, Fougner SL, Pernow Y, Aas T, Hessman O, Ros\u00e9n T, Nordenstr\u00f6m J, Jansson S, Hellstr\u00f6m M, Heck A (2023) Positive effect of parathyroidectomy compared to observation on BMD in a randomized controlled trial of mild primary hyperparathyroidism. J Bone Miner Res 38(3):372\u2013380. https:\/\/doi.org\/10.1002\/jbmr.4763. (Epub 2023 Jan 20 PMID: 36593641)","journal-title":"J Bone Miner Res"},{"key":"2086_CR33","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2007-1215","author":"MR Rubin","year":"2008","unstructured":"Rubin MR, Bilezikian JP, McMahon DJ, Jacobs T, Shane E, Siris E, Udesky J, Silverberg SJ (2008) The natural history of primary hyperparathyroidism with or without parathyroid surgery after 15 years. J Clin Endocrinol Metab. https:\/\/doi.org\/10.1210\/jc.2007-1215","journal-title":"J Clin Endocrinol Metab"},{"issue":"7368","key":"2086_CR34","doi-asserted-by":"publisher","first-page":"807","DOI":"10.1136\/bmj.325.7368.807","volume":"325","author":"CL Mollerup","year":"2002","unstructured":"Mollerup CL, Vestergaard P, Fr\u00f8kjaer VG, Mosekilde L, Christiansen P, Blichert-Toft M (2002) Risk of renal stone events in primary hyperparathyroidism before and after parathyroid surgery: controlled retrospective follow up study. BMJ 325(7368):807. https:\/\/doi.org\/10.1136\/bmj.325.7368.807","journal-title":"BMJ"},{"issue":"2","key":"2086_CR35","doi-asserted-by":"publisher","first-page":"528","DOI":"10.1002\/lary.26604","volume":"128","author":"JA Tang","year":"2018","unstructured":"Tang JA, Salapatas AM, Bonzelaar LB, Friedman M (2018) Parathyroidectomy for the treatment of hyperparathyroidism: Thirty-day morbidity and mortality. Laryngoscope 128(2):528\u2013533. https:\/\/doi.org\/10.1002\/lary.26604","journal-title":"Laryngoscope"},{"issue":"1","key":"2086_CR36","doi-asserted-by":"publisher","first-page":"102","DOI":"10.3390\/jcm13010102","volume":"13","author":"A Traba","year":"2023","unstructured":"Traba A, de Abreu A, Nevado C, Duran H, Gil A, P\u00e9rez Seoane M, Lopez-Gonzalez L, Ortega MA, \u00c1lvarez-Mon M, Martin P, San Roman J, D\u00edaz-Pedrero R (2023) Vagus nerve stimulation in the carotid triangle: an effective method for monitoring the recurrent laryngeal nerve in thyroid and parathyroid surgery. J Clin Med 13(1):102. https:\/\/doi.org\/10.3390\/jcm13010102","journal-title":"J Clin Med"},{"key":"2086_CR37","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2022.103761","author":"FJ Lorenz","year":"2023","unstructured":"Lorenz FJ, Goldenberg D (2023) Hypocalcemia after parathyroidectomy in patients taking proton pump inhibitors. Am J Otolaryngol. https:\/\/doi.org\/10.1016\/j.amjoto.2022.103761","journal-title":"Am J Otolaryngol"}],"container-title":["Updates in Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13304-025-02086-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s13304-025-02086-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13304-025-02086-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,4]],"date-time":"2025-04-04T00:27:05Z","timestamp":1743726425000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s13304-025-02086-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,30]]},"references-count":37,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["2086"],"URL":"https:\/\/doi.org\/10.1007\/s13304-025-02086-4","relation":{},"ISSN":["2038-131X","2038-3312"],"issn-type":[{"value":"2038-131X","type":"print"},{"value":"2038-3312","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,30]]},"assertion":[{"value":"20 August 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 January 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 January 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The ethics committee and review board in our institute approved the study and treatment protocol.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Research involving human participants and\/or animals"}},{"value":"Informed consent was obtained from all patients who agreed to participate in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}