{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T19:52:24Z","timestamp":1789674744585,"version":"4.0.1"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:00:00Z","timestamp":1747180800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:00:00Z","timestamp":1747180800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100003356","name":"Gazi University","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100003356","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Updates Surg"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:p>Although minimally invasive methods have become widespread, pulmonary resections due to lung cancer continue to be an important cause of postoperative morbidity. Herein, we have investigated the predicting efficacy of modified frailty index-5 (MFI-5) for postoperative complications in patients who underwent pulmonary resection by VATS for non-small cell lung cancer (NSCLC). We retrospectively reviewed the data of patients who underwent VATS lobectomy\/segmentectomy for NSCLC. MFI-5 score was calculated according to hypertension, diabetes mellitus, chronic obstructive pulmonary disease, congestive heart failure, and functional independence status. Major postoperative complications were determined based on Clavien\u2013Dindo classification. The predictive efficacy of MFI-5 score for major complications was tested by univariate and multivariate logistic regression analysis. A total of 336 patients were included in the study. The mean age was 65.6\u2009\u00b1\u20099.8\u00a0years. MFI-5 score was zero in 126 (37.5%) patients and positive in 210 patients. The major complication rate was 25.9%. Multivariate analysis showed that 2 and higher MFI-5 score significantly predicted the presence of postoperative major complications (<jats:italic>p<\/jats:italic>: 0.004, OR: 4.3, 1.58\u201312.5 95% CI). The MFI-5 score can significantly predict the presence of major postoperative complications, including 30-day mortality, in patients undergoing VATS pulmonary resection for NSCLC. <jats:italic>Clinical registration<\/jats:italic> 2024\u2013324, approved by Gazi University Local Ethics Committee.<\/jats:p>\n          <jats:p>\n            <jats:bold>Graphical abstract<\/jats:bold>\n          <\/jats:p>","DOI":"10.1007\/s13304-025-02232-y","type":"journal-article","created":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T13:41:30Z","timestamp":1747230090000},"page":"1215-1222","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Predictive value of modified frailty index-5 to major complications after videothoracoscopic pulmonary resections"],"prefix":"10.1007","volume":"77","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5402-9031","authenticated-orcid":false,"given":"Muhammet","family":"Sayan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-8589-8215","authenticated-orcid":false,"given":"Mahir","family":"Fattahov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-3598-657X","authenticated-orcid":false,"given":"Fevzi Oguzhan","family":"Temirkaynak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-8116-7330","authenticated-orcid":false,"given":"Nazmiye","family":"Koska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-4696-1781","authenticated-orcid":false,"given":"Bengisu","family":"Artiran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4123-1131","authenticated-orcid":false,"given":"Muhammet Tarik","family":"Aslan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5565-7021","authenticated-orcid":false,"given":"Gunel","family":"Ahmadova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0494-8128","authenticated-orcid":false,"given":"Aysegul","family":"Kurtoglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5427-9770","authenticated-orcid":false,"given":"Irmak","family":"Akarsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9480-010X","authenticated-orcid":false,"given":"Ismail Cuneyt","family":"Kurul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5385-6492","authenticated-orcid":false,"given":"Ali","family":"Celik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,5,14]]},"reference":[{"key":"2232_CR1","doi-asserted-by":"publisher","first-page":"M146","DOI":"10.1093\/gerona\/56.3.m146","volume":"56","author":"LP Fried","year":"2001","unstructured":"Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J et al (2001) Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci 56:M146-156. https:\/\/doi.org\/10.1093\/gerona\/56.3.m146. (PMID: 11253156)","journal-title":"J Gerontol A Biol Sci Med Sci"},{"issue":"5","key":"2232_CR2","doi-asserted-by":"publisher","first-page":"ivae179","DOI":"10.1093\/icvts\/ivae179","volume":"39","author":"M Sayan","year":"2024","unstructured":"Sayan M, Artiran B, Ozturk F, Fattahov M, Akarsu I, Aslan MT et al (2024) The prognostic significance of modified frailty index-5 in patients undergoing pneumonectomy for lung cancer. Interdiscip Cardiovasc Thorac Surg 39(5):ivae179. https:\/\/doi.org\/10.1093\/icvts\/ivae179","journal-title":"Interdiscip Cardiovasc Thorac Surg"},{"key":"2232_CR3","doi-asserted-by":"publisher","first-page":"831","DOI":"10.1016\/j.bja.2024.03.003","volume":"132","author":"M Legrand","year":"2024","unstructured":"Legrand M (2024) Should renin-angiotensin system inhibitors be held prior to major surgery? Br J Anaesth 132:831\u2013834. https:\/\/doi.org\/10.1016\/j.bja.2024.03.003","journal-title":"Br J Anaesth"},{"key":"2232_CR4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtocrr.2022.100414","volume":"3","author":"ACH Lee","year":"2022","unstructured":"Lee ACH, Lee SM, Ferguson MK (2022) Frailty is associated with adverse postoperative outcomes after lung cancer resection. JTO Clin Res Rep 3:100414. https:\/\/doi.org\/10.1016\/j.jtocrr.2022.100414","journal-title":"JTO Clin Res Rep"},{"key":"2232_CR5","doi-asserted-by":"publisher","first-page":"24","DOI":"10.5761\/atcs.oa.24-00018","volume":"30","author":"Y Koike","year":"2024","unstructured":"Koike Y, Aokage K, Osame K, Wakabayashi M, Miyoshi T, Suzuki K et al (2024) Risk factors of severe postoperative complication in lung cancer patients with diabetes mellitus. 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Thorac Cardiovasc Surg 73:71\u201377. https:\/\/doi.org\/10.1055\/a-2287-2341","journal-title":"Thorac Cardiovasc Surg"}],"container-title":["Updates in Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13304-025-02232-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s13304-025-02232-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13304-025-02232-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,15]],"date-time":"2025-07-15T15:49:54Z","timestamp":1752594594000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s13304-025-02232-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,14]]},"references-count":15,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["2232"],"URL":"https:\/\/doi.org\/10.1007\/s13304-025-02232-y","relation":{},"ISSN":["2038-131X","2038-3312"],"issn-type":[{"value":"2038-131X","type":"print"},{"value":"2038-3312","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,14]]},"assertion":[{"value":"4 March 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 April 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 May 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"None declared.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Following the approval of the  Gazi University Ethics Committee with 2024-324 registration number, the records of patients who underwent VATS-pulmonary resection for NSCLC between January 2018 and December 2023 were retrospectively reviewed. Written informed consent was obtained from all patients and\/or their legal guardians for the use of their data in a scientific study. The study procedure was conducted in accordance with the ethical standards of the Declaration of Helsinki.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval and informed consent"}}]}}