{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,8]],"date-time":"2026-11-08T01:13:07Z","timestamp":1794100387576,"version":"4.8.0"},"reference-count":70,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,1,31]],"date-time":"2023-01-31T00:00:00Z","timestamp":1675123200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["UL1 TR001414"],"award-info":[{"award-number":["UL1 TR001414"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurotherapeutics"],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1007\/s13311-022-01339-z","type":"journal-article","created":{"date-parts":[[2023,1,31]],"date-time":"2023-01-31T20:22:39Z","timestamp":1675196559000},"page":"838-852","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":45,"title":["BDNF Augmentation Using Riluzole Reverses Doxorubicin-Induced Decline in Cognitive Function and Neurogenesis"],"prefix":"10.1016","volume":"20","author":[{"given":"Manal T.","family":"Usmani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"Robert P.","family":"Krattli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanad M.","family":"El-Khatib","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anh C.D.","family":"Le","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah M.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janet E.","family":"Baulch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ding Quan","family":"Ng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Munjal M.","family":"Acharya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4391-4219","authenticated-orcid":false,"given":"Alexandre","family":"Chan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10","key":"10.1007\/s13311-022-01339-z_bib1","doi-asserted-by":"crossref","first-page":"2547","DOI":"10.1093\/annonc\/mds029","article-title":"Cognitive changes in multiethnic Asian breast cancer patients: a focus group study","volume":"23","author":"Cheung","year":"2012","journal-title":"Ann Oncol"},{"issue":"4","key":"10.1007\/s13311-022-01339-z_bib2","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1002\/pon.4635","article-title":"Distinct and heterogeneous trajectories of self-perceived cognitive impairment among Asian breast cancer survivors","volume":"27","author":"Ng","year":"2018","journal-title":"Psychooncology"},{"issue":"3","key":"10.1007\/s13311-022-01339-z_bib3","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1007\/s10549-020-05807-y","article-title":"Associations of plasma brain-derived neurotrophic factor (BDNF) and Val66Met polymorphism (rs6265) with long-term cancer-related cognitive impairment in survivors of breast cancer","volume":"183","author":"Yap","year":"2020","journal-title":"Breast Cancer Res Treat"},{"issue":"9","key":"10.1007\/s13311-022-01339-z_bib4","doi-asserted-by":"crossref","DOI":"10.3390\/brainsci11091166","article-title":"Chemotherapy-related differences in cognitive functioning and their biological predictors in patients with multiple myeloma","volume":"11","author":"Bury-Kaminska","year":"2021","journal-title":"Brain Sci."},{"key":"10.1007\/s13311-022-01339-z_bib5","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.jneuroim.2015.08.012","article-title":"Neurocognitive function, brain-derived neurotrophic factor (BDNF) and IL-6 levels in cancer patients with depression","volume":"287","author":"Jehn","year":"2015","journal-title":"J Neuroimmunol"},{"issue":"2","key":"10.1007\/s13311-022-01339-z_bib6","doi-asserted-by":"crossref","first-page":"347","DOI":"10.3109\/10428194.2014.915546","volume":"56","author":"Zimmer","year":"2015","journal-title":"Leuk Lymphoma"},{"issue":"6","key":"10.1007\/s13311-022-01339-z_bib7","doi-asserted-by":"crossref","first-page":"10434","DOI":"10.1002\/jcb.28328","article-title":"Functional rs6265 polymorphism in the brain-derived neurotrophic factor gene confers protection against neurocognitive dysfunction in posttraumatic stress disorder among Chinese patients with hepatocellular carcinoma","volume":"120","author":"Guo","year":"2019","journal-title":"J Cell Biochem"},{"issue":"3","key":"10.1007\/s13311-022-01339-z_bib8","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1177\/0891988708316860","article-title":"Serum brain-derived neurotrophic factor is associated with cognitive function in healthy older adults","volume":"21","author":"Gunstad","year":"2008","journal-title":"J Geriatr Psychiatry Neurol"},{"key":"10.1007\/s13311-022-01339-z_bib9","doi-asserted-by":"crossref","first-page":"69","DOI":"10.3389\/fnagi.2014.00069","article-title":"A large, cross-sectional observational study of serum BDNF, cognitive function, and mild cognitive impairment in the elderly","volume":"6","author":"Shimada","year":"2014","journal-title":"Front Aging Neurosci"},{"issue":"6","key":"10.1007\/s13311-022-01339-z_bib10","doi-asserted-by":"crossref","first-page":"871","DOI":"10.2217\/bmm.10.111","article-title":"Circulating levels of brain-derived neurotrophic factor: correlation with mood, cognition and motor function","volume":"4","author":"Teixeira","year":"2010","journal-title":"Biomark Med"},{"issue":"7","key":"10.1007\/s13311-022-01339-z_bib11","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1007\/s00439-012-1150-x","article-title":"Cognitive and serum BDNF correlates of BDNF Val66Met gene polymorphism in patients with schizophrenia and normal controls","volume":"131","author":"Zhang","year":"2012","journal-title":"Hum Genet"},{"issue":"1","key":"10.1007\/s13311-022-01339-z_bib12","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1186\/s12885-017-3861-9","article-title":"Evaluation of plasma brain-derived neurotrophic factor levels and self-perceived cognitive impairment post-chemotherapy: a longitudinal study","volume":"17","author":"Ng","year":"2017","journal-title":"BMC Cancer"},{"key":"10.1007\/s13311-022-01339-z_bib13","article-title":"Cognitive impairment in adolescent and young adult cancer patients: Pre-treatment findings of a longitudinal study","author":"Chan","year":"2022","journal-title":"Cancer Med."},{"issue":"6","key":"10.1007\/s13311-022-01339-z_bib14","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1080\/15376516.2019.1600086","article-title":"Doxorubicin-induced neurotoxicity is associated with acute alterations in synaptic plasticity, apoptosis, and lipid peroxidation","volume":"29","author":"Alhowail","year":"2019","journal-title":"Toxicol Mech Methods"},{"issue":"5","key":"10.1007\/s13311-022-01339-z_bib15","doi-asserted-by":"crossref","DOI":"10.3390\/brainsci10050285","article-title":"The Role of BDNF on Aging-Modulation Markers","volume":"10","author":"Molinari","year":"2020","journal-title":"Brain Sci."},{"issue":"3","key":"10.1007\/s13311-022-01339-z_bib16","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1038\/nrd3366","article-title":"Potential therapeutic uses of BDNF in neurological and psychiatric disorders","volume":"10","author":"Nagahara","year":"2011","journal-title":"Nat Rev Drug Discov"},{"issue":"10","key":"10.1007\/s13311-022-01339-z_bib17","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.1096\/fj.02-0143fje","article-title":"Riluzole enhances expression of brain-derived neurotrophic factor with consequent proliferation of granule precursor cells in the rat hippocampus","volume":"16","author":"Katoh-Semba","year":"2002","journal-title":"FASEB J"},{"issue":"2","key":"10.1007\/s13311-022-01339-z_bib18","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1111\/jnc.13230","article-title":"Riluzole rescues glutamate alterations, cognitive deficits, and tau pathology associated with P301L tau expression","volume":"135","author":"Hunsberger","year":"2015","journal-title":"J Neurochem"},{"issue":"3","key":"10.1007\/s13311-022-01339-z_bib19","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1007\/s00213-011-2403-4","article-title":"Antidepressant-like properties of oral riluzole and utility of incentive disengagement models of depression in mice","volume":"219","author":"Gourley","year":"2012","journal-title":"Psychopharmacology"},{"issue":"1","key":"10.1007\/s13311-022-01339-z_bib20","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1038\/s41398-018-0201-z","article-title":"Riluzole reduces amyloid beta pathology, improves memory, and restores gene expression changes in a transgenic mouse model of early-onset Alzheimer's disease","volume":"8","author":"Okamoto","year":"2018","journal-title":"Transl Psychiatry"},{"key":"10.1007\/s13311-022-01339-z_bib21","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.neubiorev.2020.04.007","article-title":"The medial prefrontal cortex - hippocampus circuit that integrates information of object, place and time to construct episodic memory in rodents: Behavioral, anatomical and neurochemical properties","volume":"113","author":"Chao","year":"2020","journal-title":"Neurosci Biobehav Rev"},{"issue":"11","key":"10.1007\/s13311-022-01339-z_bib22","doi-asserted-by":"crossref","first-page":"2948","DOI":"10.1523\/JNEUROSCI.5289-06.2007","article-title":"Recognition memory for objects, place, and temporal order: a disconnection analysis of the role of the medial prefrontal cortex and perirhinal cortex","volume":"27","author":"Barker","year":"2007","journal-title":"J Neurosci"},{"issue":"29","key":"10.1007\/s13311-022-01339-z_bib23","doi-asserted-by":"crossref","first-page":"10721","DOI":"10.1523\/JNEUROSCI.6413-10.2011","article-title":"When is the hippocampus involved in recognition memory?","volume":"31","author":"Barker","year":"2011","journal-title":"J Neurosci"},{"issue":"2","key":"10.1007\/s13311-022-01339-z_bib24","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1038\/nprot.2007.44","article-title":"The use of the elevated plus maze as an assay of anxiety-related behavior in rodents","volume":"2","author":"Walf","year":"2007","journal-title":"Nat Protoc"},{"issue":"4","key":"10.1007\/s13311-022-01339-z_bib25","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1037\/0097-7403.29.4.323","article-title":"Temporally massed CS presentations generate more fear extinction than spaced presentations","volume":"29","author":"Cain","year":"2003","journal-title":"J Exp Psychol Anim Behav Process"},{"key":"10.1007\/s13311-022-01339-z_bib26","doi-asserted-by":"crossref","DOI":"10.1002\/0471142301.ns0823s47","article-title":"Fear extinction in rodents","author":"Chang","year":"2009","journal-title":"Curr Protoc Neurosci."},{"issue":"3","key":"10.1007\/s13311-022-01339-z_bib27","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/j.cell.2011.10.009","article-title":"Molecular mechanisms of fear learning and memory","volume":"147","author":"Johansen","year":"2011","journal-title":"Cell"},{"issue":"17","key":"10.1007\/s13311-022-01339-z_bib28","doi-asserted-by":"crossref","first-page":"4836","DOI":"10.1073\/pnas.1521668113","article-title":"Cranial grafting of stem cell-derived microvesicles improves cognition and reduces neuropathology in the irradiated brain","volume":"113","author":"Baulch","year":"2016","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"7","key":"10.1007\/s13311-022-01339-z_bib29","doi-asserted-by":"crossref","first-page":"1954","DOI":"10.1158\/1078-0432.CCR-11-2000","article-title":"Impaired cognitive function and hippocampal neurogenesis following cancer chemotherapy","volume":"18","author":"Christie","year":"2012","journal-title":"Clin Cancer Res"},{"key":"10.1007\/s13311-022-01339-z_bib30","doi-asserted-by":"crossref","first-page":"42885","DOI":"10.1038\/srep42885","article-title":"Epigenetic determinants of space radiation-induced cognitive dysfunction","volume":"7","author":"Acharya","year":"2017","journal-title":"Sci Rep"},{"key":"10.1007\/s13311-022-01339-z_bib31","doi-asserted-by":"crossref","first-page":"42","DOI":"10.3389\/fnmol.2016.00042","article-title":"Adenosine kinase inhibition protects against cranial radiation-induced cognitive dysfunction","volume":"9","author":"Acharya","year":"2016","journal-title":"Front Mol Neurosci"},{"key":"10.1007\/s13311-022-01339-z_bib32","doi-asserted-by":"crossref","first-page":"31545","DOI":"10.1038\/srep31545","article-title":"Elimination of microglia improves cognitive function following cranial irradiation","volume":"6","author":"Acharya","year":"2016","journal-title":"Sci Rep"},{"issue":"7","key":"10.1007\/s13311-022-01339-z_bib33","doi-asserted-by":"crossref","first-page":"1732","DOI":"10.1158\/0008-5472.CAN-20-2565","article-title":"Glia-selective deletion of complement C1q prevents radiation-induced cognitive deficits and neuroinflammation","volume":"81","author":"Markarian","year":"2021","journal-title":"Cancer Res"},{"issue":"1","key":"10.1007\/s13311-022-01339-z_bib34","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1002\/sctm.18-0227","article-title":"Functional equivalence of stem cell and stem cell-derived extracellular vesicle transplantation to repair the irradiated brain","volume":"9","author":"Smith","year":"2020","journal-title":"Stem Cells Transl Med"},{"issue":"126","key":"10.1007\/s13311-022-01339-z_bib35","doi-asserted-by":"crossref","DOI":"10.3791\/55718","article-title":"Novel Object Recognition Test for the Investigation of Learning and Memory in Mice","author":"Lueptow","year":"2017","journal-title":"J Vis Exp."},{"key":"10.1007\/s13311-022-01339-z_bib36","series-title":"Methods of behavior analysis in neuroscience","article-title":"Cued and contextual fear conditioning for rodents","author":"Curzon","year":"2009"},{"issue":"4","key":"10.1007\/s13311-022-01339-z_bib37","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1158\/0008-5472.CAN-14-2237","article-title":"Stem cell transplantation reverses chemotherapy-induced cognitive dysfunction","volume":"75","author":"Acharya","year":"2015","journal-title":"Cancer Res"},{"key":"10.1007\/s13311-022-01339-z_bib38","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1146\/annurev.neuro.24.1.677","article-title":"Neurotrophins: roles in neuronal development and function","volume":"24","author":"Huang","year":"2001","journal-title":"Annu Rev Neurosci"},{"key":"10.1007\/s13311-022-01339-z_bib39","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/bs.vh.2016.10.004","article-title":"BDNF and hippocampal synaptic plasticity","volume":"104","author":"Leal","year":"2017","journal-title":"Vitam Horm"},{"issue":"1","key":"10.1007\/s13311-022-01339-z_bib40","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1186\/s40478-019-0838-8","article-title":"Attenuation of neuroinflammation reverses Adriamycin-induced cognitive impairments","volume":"7","author":"Allen","year":"2019","journal-title":"Acta Neuropathol Commun"},{"key":"10.1007\/s13311-022-01339-z_bib41","article-title":"Riluzole attenuates glutamatergic tone and cognitive decline in AbetaPP\/PS1 mice","author":"Hascup","year":"2020","journal-title":"J Neurochem."},{"key":"10.1007\/s13311-022-01339-z_bib42","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.neuropharm.2019.02.023","article-title":"Treatment with the glutamate modulator riluzole prevents early life stress-induced cognitive deficits and impairments in synaptic plasticity in APPswe\/PS1dE9 mice","volume":"150","author":"Lesuis","year":"2019","journal-title":"Neuropharmacology"},{"issue":"2\u20133","key":"10.1007\/s13311-022-01339-z_bib43","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0304-3940(01)02098-5","article-title":"Riluzole stimulates nerve growth factor, brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor synthesis in cultured mouse astrocytes","volume":"310","author":"Mizuta","year":"2001","journal-title":"Neurosci Lett"},{"key":"10.1007\/s13311-022-01339-z_bib44","doi-asserted-by":"crossref","first-page":"103748","DOI":"10.1016\/j.critrevonc.2022.103748","article-title":"Evidence of brain-derived neurotrophic factor in ameliorating cancer-related cognitive impairment: A systematic review of human studies","volume":"176","author":"Ng","year":"2022","journal-title":"Crit Rev Oncol Hematol"},{"key":"10.1007\/s13311-022-01339-z_bib45","doi-asserted-by":"crossref","first-page":"155556","DOI":"10.1016\/j.cyto.2021.155556","article-title":"Relationship between cytokines and brain-derived neurotrophic factor (BDNF) in trajectories of cancer-related cognitive impairment","volume":"144","author":"Yap","year":"2021","journal-title":"Cytokine"},{"key":"10.1007\/s13311-022-01339-z_bib46","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1007\/978-3-642-45106-5_9","article-title":"BDNF and synaptic plasticity, cognitive function, and dysfunction","volume":"220","author":"Lu","year":"2014","journal-title":"Handb Exp Pharmacol"},{"issue":"6056","key":"10.1007\/s13311-022-01339-z_bib47","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1038\/319774a0","article-title":"Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5","volume":"319","author":"Morris","year":"1986","journal-title":"Nature"},{"key":"10.1007\/s13311-022-01339-z_bib48","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/j.neuropharm.2018.02.013","article-title":"Physical exercise prevents cognitive impairment by enhancing hippocampal neuroplasticity and mitochondrial function in doxorubicin-induced chemobrain","volume":"133","author":"Park","year":"2018","journal-title":"Neuropharmacology"},{"issue":"11","key":"10.1007\/s13311-022-01339-z_bib49","doi-asserted-by":"crossref","first-page":"2311","DOI":"10.1007\/s00213-013-3394-0","article-title":"Physical exercise prevents suppression of hippocampal neurogenesis and reduces cognitive impairment in chemotherapy-treated rats","volume":"231","author":"Winocur","year":"2014","journal-title":"Psychopharmacology"},{"key":"10.1007\/s13311-022-01339-z_bib50","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1007\/7854_2012_220","article-title":"All about running: synaptic plasticity, growth factors and adult hippocampal neurogenesis","volume":"15","author":"Vivar","year":"2013","journal-title":"Curr Top Behav Neurosci"},{"key":"10.1007\/s13311-022-01339-z_bib51","article-title":"Feasibility of cognitive training to promote recovery in cancer-related cognitive impairment in adolescent and young adult patients","author":"Gooch","year":"2021","journal-title":"J Adolesc Young Adult Oncol."},{"issue":"4","key":"10.1007\/s13311-022-01339-z_bib52","doi-asserted-by":"crossref","first-page":"e0231379","DOI":"10.1371\/journal.pone.0231379","article-title":"Clinical impact of melatonin on breast cancer patients undergoing chemotherapy; effects on cognition, sleep and depressive symptoms: A randomized, double-blind, placebo-controlled trial","volume":"15","author":"Palmer","year":"2020","journal-title":"PLoS ONE"},{"key":"10.1007\/s13311-022-01339-z_bib53","doi-asserted-by":"crossref","first-page":"2919","DOI":"10.12659\/MSM.909712","article-title":"Efficacy of acupuncture therapy for chemotherapy-related cognitive impairment in breast cancer patients","volume":"24","author":"Tong","year":"2018","journal-title":"Med Sci Monit"},{"issue":"2","key":"10.1007\/s13311-022-01339-z_bib54","doi-asserted-by":"crossref","first-page":"e13150","DOI":"10.2196\/13150","article-title":"Mediators of a physical activity intervention on cognition in breast cancer survivors: evidence from a randomized controlled trial","volume":"5","author":"Hartman","year":"2019","journal-title":"JMIR Cancer"},{"issue":"26","key":"10.1007\/s13311-022-01339-z_bib55","doi-asserted-by":"crossref","first-page":"6251","DOI":"10.1523\/JNEUROSCI.4601-04.2005","article-title":"Brain-derived neurotrophic factor is required for the establishment of the proper number of dopaminergic neurons in the substantia nigra pars compacta","volume":"25","author":"Baquet","year":"2005","journal-title":"J Neurosci"},{"key":"10.1007\/s13311-022-01339-z_bib56","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.brainres.2018.10.006","article-title":"Plasma levels of brain-derived neurotrophic factor in patients with Parkinson disease: a systematic review and meta-analysis","volume":"1704","author":"Rahmani","year":"2019","journal-title":"Brain Res"},{"issue":"1","key":"10.1007\/s13311-022-01339-z_bib57","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/S0166-2236(00)01682-9","article-title":"BDNF and epilepsy: too much of a good thing?","volume":"24","author":"Binder","year":"2001","journal-title":"Trends Neurosci"},{"issue":"1","key":"10.1007\/s13311-022-01339-z_bib58","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1038\/sj.npp.1301555","article-title":"Neural mechanisms of extinction learning and retrieval","volume":"33","author":"Quirk","year":"2008","journal-title":"Neuropsychopharmacology"},{"issue":"6","key":"10.1007\/s13311-022-01339-z_bib59","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1038\/npp.2016.274","article-title":"Context and auditory fear are differentially regulated by HDAC3 activity in the lateral and basal subnuclei of the amygdala","volume":"42","author":"Kwapis","year":"2017","journal-title":"Neuropsychopharmacology"},{"issue":"1","key":"10.1007\/s13311-022-01339-z_bib60","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1007\/s00213-018-5084-4","article-title":"Neuroepigenetic mechanisms underlying fear extinction: emerging concepts","volume":"236","author":"Marshall","year":"2019","journal-title":"Psychopharmacology"},{"key":"10.1007\/s13311-022-01339-z_bib61","doi-asserted-by":"crossref","first-page":"155653","DOI":"10.1016\/j.cyto.2021.155653","article-title":"Cancer-related cognitive impairment is associated with perturbations in inflammatory pathways","volume":"148","author":"Oppegaard","year":"2021","journal-title":"Cytokine"},{"issue":"1","key":"10.1007\/s13311-022-01339-z_bib62","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.nbd.2006.02.013","article-title":"Adriamycin-induced, TNF-alpha-mediated central nervous system toxicity","volume":"23","author":"Tangpong","year":"2006","journal-title":"Neurobiol Dis"},{"issue":"5","key":"10.1007\/s13311-022-01339-z_bib63","doi-asserted-by":"crossref","first-page":"3295","DOI":"10.1007\/s12035-018-1283-6","article-title":"Brain-derived neurotrophic factor in brain disorders: focus on neuroinflammation","volume":"56","author":"Lima Giacobbo","year":"2019","journal-title":"Mol Neurobiol"},{"issue":"2","key":"10.1007\/s13311-022-01339-z_bib64","doi-asserted-by":"crossref","first-page":"e92","DOI":"10.1016\/S1470-2045(18)30938-0","article-title":"Pharmacologic management of cognitive impairment induced by cancer therapy","volume":"20","author":"Karschnia","year":"2019","journal-title":"Lancet Oncol"},{"key":"10.1007\/s13311-022-01339-z_bib65","article-title":"Cancer-related cognitive impairment in patients with non-central nervous system malignancies: an overview for oncology providers from the MASCC Neurological Complications Study Group","author":"Mayo","year":"2020","journal-title":"Support Care Cancer."},{"key":"10.1007\/s13311-022-01339-z_bib66","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.bbi.2020.12.011","article-title":"Nasal administration of mesenchymal stem cells reverses chemotherapy-induced peripheral neuropathy in mice","volume":"93","author":"Boukelmoune","year":"2021","journal-title":"Brain Behav Immun"},{"issue":"8","key":"10.1007\/s13311-022-01339-z_bib67","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21082755","article-title":"Role of exosomes in cancer-related cognitive impairment","volume":"21","author":"Koh","year":"2020","journal-title":"Int J Mol Sci."},{"key":"10.1007\/s13311-022-01339-z_bib68","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.peptides.2017.12.027","article-title":"Moderate treadmill exercise ameliorates amyloid-beta-induced learning and memory impairment, possibly via increasing AMPK activity and up-regulation of the PGC-1alpha\/FNDC5\/BDNF pathway","volume":"102","author":"Azimi","year":"2018","journal-title":"Peptides"},{"issue":"3","key":"10.1007\/s13311-022-01339-z_bib69","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21031170","article-title":"BDNF as a promising therapeutic agent in Parkinson's disease","volume":"21","author":"Palasz","year":"2020","journal-title":"Int J Mol Sci."},{"issue":"5","key":"10.1007\/s13311-022-01339-z_bib70","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1179\/1476830511Y.0000000011","article-title":"The effect of the Mediterranean diet on plasma brain-derived neurotrophic factor (BDNF) levels: the PREDIMED-NAVARRA randomized trial","volume":"14","author":"Sanchez-Villegas","year":"2011","journal-title":"Nutr Neurosci"}],"updated-by":[{"DOI":"10.1007\/s13311-023-01381-5","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000}}],"container-title":["Neurotherapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13311-022-01339-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s13311-022-01339-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S187874792300020X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S187874792300020X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13311-022-01339-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,8]],"date-time":"2024-01-08T11:17:01Z","timestamp":1704712621000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S187874792300020X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":70,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,4]]}},"alternative-id":["S187874792300020X"],"URL":"https:\/\/doi.org\/10.1007\/s13311-022-01339-z","relation":{"erratum":[{"id-type":"doi","id":"10.1007\/s13311-023-01381-5","asserted-by":"object"}]},"ISSN":["1878-7479"],"issn-type":[{"value":"1878-7479","type":"print"}],"subject":[],"published":{"date-parts":[[2023,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"BDNF Augmentation Using Riluzole Reverses Doxorubicin-Induced Decline in Cognitive Function and Neurogenesis","name":"articletitle","label":"Article Title"},{"value":"Neurotherapeutics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1007\/s13311-022-01339-z","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1007\/s13311-023-01381-5","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2023 The American Society for Experimental NeuroTherapeutics, Inc. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}