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S. El-Kadi: conceptualization, supervision, writing\u2014review and editing, visualization, project administration, funding acquisition. Sara A. Helal: methodology, validation, formal analysis, investigation, writing\u2014original draft, visualization. Samar H. Gerges: writing\u2014review and editing. All authors have read and approved the manuscript.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Author Contributions"}},{"value":"Not applicable","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Code Availability"}},{"value":"All the animal experimental procedures adhered to the Guide for the Care and Use of Laboratory Animals, as established by the US National Institutes of Health, and were approved by the Alberta Health Sciences Animal Policy and Welfare, Study number (AUP00000249)","order":7,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval"}}]}}