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Potential COI concerning all individual investigators were reviewed by the Certified Review Board in accordance with the Clinical Trials Act []. The COI of the members of the writing group are as follows: YH received lecture fees from Abbott, Eli Lilly, Sanofi, Novo Nordisk, Sumitomo, and Terumo and received a research grant from Sumitomo, Kyowa Kirin, and Medtronic Japan and a donation from Abbott Japan. MM received lecture fees from Abbott, Boehringer Ingelheim, Eli Lilly, Novo Nordisk, Orizuru Therapeutics, Sanofi, Sumitomo, and Terumo. SM received lecture fees from Eli Lilly, Kowa, Sumitomo, and Novo Nordisk. JM received lecture fees from Novo Nordisk. AT received lecture fees from Abbott, Eli Lilly, Sanofi, and Terumo. MT received lecture fees from Boehringer Ingelheim, Eli Lilly, Novo Nordisk, Sumitomo, and Mitsubishi Tanabe and received subsidies from Cocokara Fine Healthcare, LifeScan, Roche DC, and Super Light Water. TM received a research grant from Medtronic. KH, KK, AS, AK, NK, NS, and AI declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Informed consent or an appropriate substitute was obtained from all patients prior to their inclusion in the study. The study protocol was approved by the Certified Review Board (National Hospital Organization Osaka National Hospital: N2018002). Clinical trial registration: jRCT1052180075 (approval date of registry; 26 February 2019).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and\/or with the Helsinki Declaration of 1964 and later versions.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Human rights"}}]}}