{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T02:11:13Z","timestamp":1790820673590,"version":"4.1.0"},"reference-count":12,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2015,12,28]],"date-time":"2015-12-28T00:00:00Z","timestamp":1451260800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Drug Deliv. and Transl. Res."],"DOI":"10.1007\/s13346-015-0267-6","type":"journal-article","created":{"date-parts":[[2015,12,28]],"date-time":"2015-12-28T12:01:38Z","timestamp":1451304098000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Solid lipid nanoparticles of amphotericin B (AmbiOnp): in vitro and in vivo assessment towards safe and effective oral treatment module"],"prefix":"10.1007","author":[{"given":"Manisha B.","family":"Chaudhari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Preshita P.","family":"Desai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pratikkumar A.","family":"Patel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vandana B.","family":"Patravale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,12,28]]},"reference":[{"issue":"5","key":"267_CR1","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1166\/jbn.2011.1332","volume":"7","author":"PA Patel","year":"2011","unstructured":"Patel PA, Patravale VB. AmbiOnp: solid lipid nanoparticles of amphotericin B for oral administration. J Biomed Nanotechnol. 2011;7(5):632\u20139.","journal-title":"J Biomed Nanotechnol"},{"issue":"3","key":"267_CR2","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1086\/600105","volume":"200","author":"KM Wasan","year":"2009","unstructured":"Wasan KM, Wasan EK, Gershkovich P, Zhu X, Tidwell RR, Werbovetz KA, et al. Highly effective oral amphotericin B formulation against murine visceral leishmaniasis. J Infect Dis. 2009;200(3):357\u201360.","journal-title":"J Infect Dis"},{"issue":"2","key":"267_CR3","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0009-3084(96)02652-7","volume":"85","author":"J Barwicz","year":"1997","unstructured":"Barwicz J, Tancr\u00e8de P. The effect of aggregation state of amphotericin-B on its interactions with cholesterol- or ergosterol-containing phosphatidylcholine monolayers. Chem Phys Lipids. 1997;85(2):145\u201355.","journal-title":"Chem Phys Lipids"},{"issue":"23","key":"267_CR4","doi-asserted-by":"crossref","first-page":"5707","DOI":"10.1021\/bi00237a011","volume":"30","author":"J Bolard","year":"1991","unstructured":"Bolard J, Legrand P, Heitz F, Cybulska B. One-sided action of amphotericin B on cholesterol-containing membranes is determined by its self-association in the medium. Biochemistry. 1991;30(23):5707\u201315.","journal-title":"Biochemistry"},{"issue":"6","key":"267_CR5","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1007\/s11095-009-9841-2","volume":"26","author":"JL Italia","year":"2009","unstructured":"Italia JL, Yahya MM, Singh D, Ravi Kumar MN. Biodegradable nanoparticles improve oral bioavailability of amphotericin B and show reduced nephrotoxicity compared to intravenous Fungizone. Pharm Res. 2009;26(6):1324\u201331.","journal-title":"Pharm Res"},{"issue":"3","key":"267_CR6","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1023\/A:1016212804288","volume":"12","author":"GL Amidon","year":"1995","unstructured":"Amidon GL, Lennern\u00e4s H, Shah VP, Crison JR. A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability. Pharm Res. 1995;12(3):413\u201320.","journal-title":"Pharm Res"},{"issue":"5","key":"267_CR7","first-page":"295","volume":"5","author":"DB Louria","year":"1958","unstructured":"Louria DB. Some aspects of the absorption, distribution, and excretion of amphotericin B in man. Antibiotic Med Clin Ther. 1958;5(5):295\u2013301.","journal-title":"Antibiotic Med Clin Ther"},{"issue":"7","key":"267_CR8","doi-asserted-by":"crossref","first-page":"2405","DOI":"10.1002\/jps.21179","volume":"97","author":"JJ Torrado","year":"2008","unstructured":"Torrado JJ, Espada R, Ballesteros MP, Torrado-Santiago S. Amphotericin B formulations and drug targeting. J Pharm Sci. 2008;97(7):2405\u201325.","journal-title":"J Pharm Sci"},{"issue":"1","key":"267_CR9","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/S1011-1344(02)00405-0","volume":"69","author":"WI Gruszecki","year":"2003","unstructured":"Gruszecki WI, Gago\u015b M, Here\u0107 M. Dimers of polyene antibiotic amphotericin B detected by means of fluorescence spectroscopy: molecular organization in solution and in lipid membranes. J Photochem Photobiol B. 2003;69(1):49\u201357.","journal-title":"J Photochem Photobiol B"},{"issue":"2","key":"267_CR10","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/0005-2736(90)90305-8","volume":"1030","author":"P Tancr\u00e8de","year":"1990","unstructured":"Tancr\u00e8de P, Barwicz J, Jutras S, Gruda I. The effect of surfactants on the aggregation state of amphotericin B. Biochim Biophys Acta. 1990;1030(2):289\u201395.","journal-title":"Biochim Biophys Acta"},{"issue":"1\u20132","key":"267_CR11","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.ijpharm.2008.05.013","volume":"361","author":"R Espada","year":"2008","unstructured":"Espada R, Valdespina S, Alfonso C, Rivas G, Ballesteros MP, Torrado JJ. Effect of aggregation state on the toxicity of different amphotericin B preparations. Int J Pharm. 2008;361(1\u20132):64\u20139.","journal-title":"Int J Pharm"},{"issue":"2","key":"267_CR12","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.exppara.2009.07.002","volume":"123","author":"M Duarte","year":"2009","unstructured":"Duarte M, Giordani RB, De Carli GA, Zuanazzi JA, Macedo AJ, Tasca T. A quantitative resazurin assay to determinate the viability of Trichomonas vaginalis and the cytotoxicity of organic solvents and surfactant agents. Exp Parasitol. 2009;123(2):195\u20138.","journal-title":"Exp Parasitol"}],"container-title":["Drug Delivery and Translational Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s13346-015-0267-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s13346-015-0267-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s13346-015-0267-6","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,2]],"date-time":"2019-06-02T11:55:16Z","timestamp":1559476516000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s13346-015-0267-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12,28]]},"references-count":12,"alternative-id":["267"],"URL":"https:\/\/doi.org\/10.1007\/s13346-015-0267-6","relation":{},"ISSN":["2190-393X","2190-3948"],"issn-type":[{"value":"2190-393X","type":"print"},{"value":"2190-3948","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,12,28]]}}}