{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:34:10Z","timestamp":1772120050354,"version":"3.50.1"},"reference-count":51,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2022,3,7]],"date-time":"2022-03-07T00:00:00Z","timestamp":1646611200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,3,7]],"date-time":"2022-03-07T00:00:00Z","timestamp":1646611200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Drug Deliv. and Transl. Res."],"published-print":{"date-parts":[[2022,11]]},"DOI":"10.1007\/s13346-022-01122-9","type":"journal-article","created":{"date-parts":[[2022,3,7]],"date-time":"2022-03-07T10:02:46Z","timestamp":1646647366000},"page":"2708-2729","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Development and pharmacokinetic evaluation of osmotically controlled drug delivery system of Valganciclovir HCl for potential application in the treatment of CMV retinitis"],"prefix":"10.1007","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5899-0893","authenticated-orcid":false,"given":"Ramakanth","family":"Gundu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjay","family":"Pekamwar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5904-6028","authenticated-orcid":false,"given":"Santosh","family":"Shelke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5992-5903","authenticated-orcid":false,"given":"Deepak","family":"Kulkarni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dipak","family":"Gadade","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Santosh","family":"Shep","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,3,7]]},"reference":[{"issue":"3","key":"1122_CR1","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1007\/s40506-014-0021-5","volume":"6","author":"BH Tan","year":"2014","unstructured":"Tan BH. Cytomegalovirus treatment. Curr Treat Options Infect Dis. 2014;6(3):256\u201370. https:\/\/doi.org\/10.1007\/s40506-014-0021-5.","journal-title":"Curr Treat Options Infect Dis"},{"issue":"3","key":"1122_CR2","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1155\/1996\/780831","volume":"7","author":"A Tseng","year":"1996","unstructured":"Tseng A, Foisy M. The role of ganciclovir for the management of cytomegalovirus retinitis in HIV patients: pharmacological review and update on new developments. Can J Infect Dis. 1996;7(3):183\u201394. https:\/\/doi.org\/10.1155\/1996\/780831.","journal-title":"Can J Infect Dis"},{"issue":"6","key":"1122_CR3","doi-asserted-by":"publisher","first-page":"859","DOI":"10.2165\/00003495-200565060-00012","volume":"65","author":"RS Cvetkovi\u0107","year":"2005","unstructured":"Cvetkovi\u0107 RS, Wellington K. Valganciclovir: a review of its use in the management of CMV infection and disease in immunocompromised patients. Drugs. 2005;65(6):859\u201378. https:\/\/doi.org\/10.2165\/00003495-200565060-00012.","journal-title":"Drugs"},{"issue":"12","key":"1122_CR4","first-page":"1185","volume":"19","author":"S Vaziri","year":"2014","unstructured":"Vaziri S, Pezhman Z, Sayyad B, Mansouri F, Janbakhsh A, Afsharian M, N. F. Efficacy of valganciclovir and ganciclovir for cytomegalovirus disease in solid organ transplants: ameta-analysis. J Res Med Sci. 2014;19(12):1185\u201392.","journal-title":"J Res Med Sci"},{"issue":"23","key":"1122_CR5","first-page":"1","volume":"2","author":"JA Ahmed","year":"2015","unstructured":"Ahmed JA. A review on immediate release tablet dosage form. Int J Pharm Pharm Res. 2015;2(23):1\u201317.","journal-title":"International Journal of Pharmacy and Pharmaceutical Research"},{"issue":"5","key":"1122_CR6","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1007\/s13346-016-0305-z","volume":"6","author":"P Bhusal","year":"2016","unstructured":"Bhusal P, Harrison J, Sharma M, Jones DS, Hill AG, Svirskis D. Controlled release drug delivery systems to improve post-operative pharmacotherapy. Drug Deliv Transl Res. 2016;6(5):441\u201351. https:\/\/doi.org\/10.1007\/s13346-016-0305-z.","journal-title":"Drug Deliv Transl Res"},{"issue":"3","key":"1122_CR7","doi-asserted-by":"publisher","first-page":"588","DOI":"10.1016\/j.ophtha.2011.09.004","volume":"119","author":"SC Teoh","year":"2012","unstructured":"Teoh SC, Ou X, Lim TH. Intravitreal ganciclovir maintenance injection for cytomegalovirus retinitis: efficacy of a low-volume, intermediate-dose regimen. Ophthalmology. 2012;119(3):588\u201395. https:\/\/doi.org\/10.1016\/j.ophtha.2011.09.004.","journal-title":"Ophthalmology"},{"key":"1122_CR8","doi-asserted-by":"publisher","DOI":"10.1016\/j.eurpolymj.2020.110155","volume":"142","author":"P Jana","year":"2021","unstructured":"Jana P, Shyam M, Singh S, Jayaprakash V, Dev A. Biodegradable polymers in drug delivery and oral vaccination. Eur Polymer J. 2021;142: 110155. https:\/\/doi.org\/10.1016\/j.eurpolymj.2020.110155.","journal-title":"Eur Polymer J"},{"issue":"1","key":"1122_CR9","first-page":"218","volume":"20","author":"J Chourasiya","year":"2013","unstructured":"Chourasiya J, Keshavrao Kamble R, Singh Tanwar Y. Novel approaches in extended release drug delivery systems. Int J Pharm Sci Rev Res. 2013;20(1):218\u201327.","journal-title":"International Journal of Pharmaceutical Sciences Review and Research"},{"key":"1122_CR10","doi-asserted-by":"publisher","first-page":"1","DOI":"10.5402\/2012\/528079","volume":"2012","author":"RA Keraliya","year":"2012","unstructured":"Keraliya RA, Patel C, Patel P, Keraliya V, Soni TG, Patel RC, Patel MM. Osmotic drug delivery system as a part of modified release dosage form. ISRN Pharmaceutics. 2012;2012:1\u20139. https:\/\/doi.org\/10.5402\/2012\/528079.","journal-title":"ISRN Pharmaceutics"},{"issue":"3","key":"1122_CR11","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1586\/14750708.2.3.333","volume":"2","author":"A Humar","year":"2005","unstructured":"Humar A. Valganciclovir for cytomegalovirus prevention and treatment. Therapy. 2005;2(3):333\u201341. https:\/\/doi.org\/10.1586\/14750708.2.3.333.","journal-title":"Therapy"},{"issue":"2","key":"1122_CR12","doi-asserted-by":"publisher","first-page":"124","DOI":"10.4103\/2231-4040.97292","volume":"3","author":"A Bathool","year":"2012","unstructured":"Bathool A, Gowda DV, Khan MS, Ahmed A, Vasudha SL, Rohitash K. Development and evaluation of microporous osmotic tablets of diltiazem hydrochloride. Journal of Advanced Pharmaceutical Technology and Research. 2012;3(2):124\u20139. https:\/\/doi.org\/10.4103\/2231-4040.97292.","journal-title":"Journal of Advanced Pharmaceutical Technology and Research"},{"issue":"1","key":"1122_CR13","doi-asserted-by":"publisher","first-page":"2","DOI":"10.4103\/0976-0105.109398","volume":"4","author":"F Dasankoppa","year":"2013","unstructured":"Dasankoppa F, Ningangowdar M, Sholapur H. Formulation and evaluation of controlled porosity osmotic pump for oral delivery of ketorolac. Journal of Basic and Clinical Pharmacy. 2013;4(1):2. https:\/\/doi.org\/10.4103\/0976-0105.109398.","journal-title":"Journal of Basic and Clinical Pharmacy"},{"issue":"1","key":"1122_CR14","first-page":"11","volume":"15","author":"S Pekamwar","year":"2021","unstructured":"Pekamwar S, Kulkarni D, Gadade D. Accidental formation of eutectics during crystal engineering of lamotrigine. Asian J Pharm. 2021;15(1):11\u20132.","journal-title":"Asian J Pharm"},{"issue":"2","key":"1122_CR15","doi-asserted-by":"publisher","first-page":"277","DOI":"10.4172\/pharmaceutical-sciences.1000226","volume":"79","author":"DD Gadade","year":"2017","unstructured":"Gadade DD, Kulkarni DA, Rathi PB, Pekamwar SS, Joshi SS. Solubility enhancement of lornoxicam by crystal engineering. Indian J Pharm Sci. 2017;79(2):277\u201386. https:\/\/doi.org\/10.4172\/pharmaceutical-sciences.1000226.","journal-title":"Indian J Pharm Sci"},{"key":"1122_CR16","doi-asserted-by":"publisher","unstructured":"Gundu R, Pekamwar S, Shelke S, Shep S, Kulkarni D (2020) Sustained release formulation of Ondansetron\u00a0HCl using osmotic drug delivery approach.\u00a0Drug Dev Ind Pharm. 46(3).\u00a0https:\/\/doi.org\/10.1080\/03639045.2020.1716372.","DOI":"10.1080\/03639045.2020.1716372"},{"issue":"4","key":"1122_CR17","first-page":"114","volume":"5","author":"M Kulshrestha","year":"2013","unstructured":"Kulshrestha M, Kulshrestha R. Formulation and evaluation of osmotic pump tablet of cefadroxil. Int J Pharm Pharm Sci. 2013;5(4):114\u20138.","journal-title":"Int J Pharm Pharm Sci"},{"issue":"4","key":"1122_CR18","doi-asserted-by":"publisher","first-page":"208","DOI":"10.1016\/j.ajps.2014.05.003","volume":"9","author":"T Xin","year":"2014","unstructured":"Xin T, Zhao Y, Jing H, Zhang W, Gao Y, Yang X, Qu X, Pan W. A time-released osmotic pump fabricated by compression-coated method: formulation screen, mechanism research and pharmacokinetic study. Asian J Pharm Sci. 2014;9(4):208\u201317. https:\/\/doi.org\/10.1016\/j.ajps.2014.05.003.","journal-title":"Asian J Pharm Sci"},{"key":"1122_CR19","doi-asserted-by":"publisher","unstructured":"Patil PR, Bobade VD, Sawant PL, Marathe RP (2016) Emerging trends in compression coated tablet dosage forms: a review.\u00a0Int J Pharm Sci Res. 7(3), 930\u2013938.\u00a0https:\/\/doi.org\/10.13040\/IJPSR.0975-8232.7(3).930--38.","DOI":"10.13040\/IJPSR.0975-8232.7(3).930--38"},{"key":"1122_CR20","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2016\/9024173","volume":"2016","author":"A Patel","year":"2016","unstructured":"Patel A, Dodiya H, Shelate P, Shastri D, Dave D. Design, characterization, and optimization of controlled drug delivery system containing antibiotic drug\/s. Journal of Drug Delivery. 2016;2016:1\u201315. https:\/\/doi.org\/10.1155\/2016\/9024173.","journal-title":"Journal of Drug Delivery"},{"issue":"12","key":"1122_CR21","doi-asserted-by":"publisher","first-page":"69","DOI":"10.53879\/id.54.12.10959","volume":"54","author":"A Kumar","year":"2017","unstructured":"Kumar A, Singh BK, Joshi DK. Development of aceclofenac osmotic pump tablet for controlled drug delivery. Indian Drugs. 2017;54(12):69\u201371.","journal-title":"Indian Drugs"},{"key":"1122_CR22","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1186\/s43094-021-00311-6","volume":"7","author":"R Gundu","year":"2021","unstructured":"Gundu R, Pekamwar S, Shelke S, Kulkarni D, Shep S. Development, optimization and pharmacokinetic evaluation of biphasic extended-release osmotic drug delivery system of trospium chloride for promising application in treatment of overactive bladder. Futur J Pharm Sci. 2021;7:160. https:\/\/doi.org\/10.1186\/s43094-021-00311-6.","journal-title":"Futur J Pharm Sci"},{"issue":"2","key":"1122_CR23","doi-asserted-by":"publisher","first-page":"64","DOI":"10.5530\/phm.2018.2.12","volume":"9","author":"S Mondal","year":"2018","unstructured":"Mondal S, Goluguri SR, Mondal P, Prathyusha VS. Development and validation of few UV Spectrophotometric methods for the determination of Valganciclovir in bulk and pharmaceutical dosage form. Pharmaceutical Methods. 2018;9(2):64\u20138.","journal-title":"Pharmaceutical Methods"},{"issue":"1","key":"1122_CR24","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1515\/chem-2020-0028","volume":"18","author":"P Pudjiastuti","year":"2020","unstructured":"Pudjiastuti P, Wafiroh S, Hendradi E, Darmokoesoemo H, Harsini M, Nahar L, Sarker SD. Disintegration, in vitro dissolution, and drug release kinetics profiles of k-Carrageenan-based nutraceutical hard-shell capsules Containing Salicylamide. Open Chem. 2020;18(1):226\u201331. https:\/\/doi.org\/10.1515\/chem-2020-0028.","journal-title":"Open Chem"},{"issue":"1","key":"1122_CR25","doi-asserted-by":"publisher","first-page":"2","DOI":"10.4103\/0976-0105.109398","volume":"4","author":"FS Dasankoppa","year":"2012","unstructured":"Dasankoppa FS, Ningangowdar M, Sholapur H. Formulation and evaluation of controlled porosity osmotic pump for oral delivery of ketorolac. Journal of basic and clinical pharmacy. 2012;4(1):2\u20139. https:\/\/doi.org\/10.4103\/0976-0105.109398.","journal-title":"Journal of basic and clinical pharmacy"},{"issue":"1","key":"1122_CR26","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1208\/s12249-013-0040-4","volume":"15","author":"S Missaghi","year":"2014","unstructured":"Missaghi S, Patel P, Farrell TP, Huatan H, Rajabi-Siahboomi AR. Investigation of critical core formulation and process parameters for osmotic pump oral drug delivery. AAPS PharmSciTech. 2014;15(1):149\u201360. https:\/\/doi.org\/10.1208\/s12249-013-0040-4.","journal-title":"AAPS PharmSciTech"},{"issue":"3","key":"1122_CR27","doi-asserted-by":"publisher","first-page":"1189","DOI":"10.1016\/j.xphs.2018.10.014","volume":"108","author":"Z Gao","year":"2019","unstructured":"Gao Z, Ngo C, Ye W, Rodriguez JD, Keire D, Sun D, Wen H, Jiang W. Effects of dissolution medium pH and simulated gastrointestinal contraction on drug release from nifedipine extended-release tablets. J Pharm Sci. 2019;108(3):1189\u201394. https:\/\/doi.org\/10.1016\/j.xphs.2018.10.014.","journal-title":"J Pharm Sci"},{"issue":"4","key":"1122_CR28","doi-asserted-by":"publisher","first-page":"759","DOI":"10.1208\/s12249-015-0356-3","volume":"16","author":"N Seeger","year":"2015","unstructured":"Seeger N, Lange S, Klein S. Impact of vibration and agitation speed on dissolution of USP prednisone tablets RS and various IR tablet formulations. AAPS PharmSciTech. 2015;16(4):759\u201366. https:\/\/doi.org\/10.1208\/s12249-015-0356-3.","journal-title":"AAPS PharmSciTech"},{"issue":"4","key":"1122_CR29","doi-asserted-by":"publisher","first-page":"238","DOI":"10.4103\/2230-973X.195951","volume":"6","author":"N Arjun","year":"2016","unstructured":"Arjun N, Narendar D, Sunitha K, Harika K, Nagaraj B. Development, evaluation, and influence of formulation and process variables on in vitro performance of oral elementary osmotic device of atenolol. International journal of pharmaceutical investigation. 2016;6(4):238\u201346. https:\/\/doi.org\/10.4103\/2230-973X.195951.","journal-title":"International journal of pharmaceutical investigation"},{"issue":"June","key":"1122_CR30","first-page":"247","volume":"8","author":"BPRM Geetha","year":"2009","unstructured":"Geetha BPRM, Purushothama N, Sanki U. Optimization and development of swellable controlled porosity osmotic pump tablet for theophylline. 2009;8(June):247\u201355.","journal-title":"Optimization and development of swellable controlled porosity osmotic pump tablet for theophylline"},{"issue":"3","key":"1122_CR31","doi-asserted-by":"publisher","first-page":"1016","DOI":"10.1208\/s12249-008-9135-8","volume":"9","author":"AH Elshafeey","year":"2008","unstructured":"Elshafeey AH, Sami EI. Preparation and in-vivo pharmacokinetic study of a novel extended release compression coated tablets of fenoterol hydrobromide. AAPS PharmSciTech. 2008;9(3):1016\u201324. https:\/\/doi.org\/10.1208\/s12249-008-9135-8.","journal-title":"AAPS PharmSciTech"},{"issue":"8","key":"1122_CR32","doi-asserted-by":"publisher","first-page":"1035","DOI":"10.1007\/s12272-001-1265-7","volume":"31","author":"YS Rhee","year":"2008","unstructured":"Rhee YS, Park JH, Park S, Park CW, Ha JM, Jeong KW, Lee DS, Park ES. Analysis of acamprosate in beagle dog plasma by LC-MS-MS. Arch Pharmacal Res. 2008;31(8):1035\u20139. https:\/\/doi.org\/10.1007\/s12272-001-1265-7.","journal-title":"Arch Pharmacal Res"},{"key":"1122_CR33","doi-asserted-by":"publisher","unstructured":"Gupta BP, Thakur N, Jain NP, Banweer J, Jain S (2010) Osmotically controlled drug delivery system with associated drugs.\u00a0J Pharm Pharm Sci. 13(4), 571\u2013588. https:\/\/doi.org\/10.18433\/j38w25.","DOI":"10.18433\/j38w25"},{"key":"1122_CR34","doi-asserted-by":"publisher","unstructured":"Kaushik S, Pathak K (2016) Development and evaluation of monolithic osmotic tablet of ketoprofen: using solid dispersion technique.\u00a0Int J Pharm Pharm Sci. 8(12), 41\u201347.\u00a0https:\/\/doi.org\/10.22159\/ijpps.2016v8i12.11437.","DOI":"10.22159\/ijpps.2016v8i12.11437"},{"key":"1122_CR35","doi-asserted-by":"publisher","unstructured":"Maheshwari R, Todke P, Kuche K, Raval N, Tekade RK (2018) Micromeritics in pharmaceutical product development. In Dosage Form Design Considerations: Volume I (Issue January). Elsevier Inc.\u00a0https:\/\/doi.org\/10.1016\/B978-0-12-814423-7.00017-4.","DOI":"10.1016\/B978-0-12-814423-7.00017-4"},{"issue":"5","key":"1122_CR36","doi-asserted-by":"publisher","first-page":"814","DOI":"10.1080\/03639045.2020.1757696","volume":"46","author":"MI Mohamed","year":"2020","unstructured":"Mohamed MI, Al-Mahallawi AM, Awadalla SM. Development and optimization of osmotically controlled drug delivery system for poorly aqueous soluble diacerein to improve its bioavailability. Drug Dev Ind Pharm. 2020;46(5):814\u201325. https:\/\/doi.org\/10.1080\/03639045.2020.1757696.","journal-title":"Drug Dev Ind Pharm"},{"issue":"2","key":"1122_CR37","doi-asserted-by":"publisher","first-page":"924","DOI":"10.1208\/s12249-010-9446-4","volume":"11","author":"S Tuntikulwattana","year":"2010","unstructured":"Tuntikulwattana S, Mitrevej A, Kerdcharoen T, Williams DB, Sinchaipanid N. Development and optimization of micro\/nanoporous osmotic pump tablets. AAPS PharmSciTech. 2010;11(2):924\u201335. https:\/\/doi.org\/10.1208\/s12249-010-9446-4.","journal-title":"AAPS PharmSciTech"},{"issue":"1","key":"1122_CR38","doi-asserted-by":"publisher","first-page":"87","DOI":"10.5530\/jyp.2017.9.17","volume":"9","author":"A Narayanan","year":"2017","unstructured":"Narayanan A, George P, Akshay D. Application of 32 factorial d-optimal design in formulation of porous osmotic pump tablets of ropinirole; an anti-Parkinson\u2019s agent. J Young Pharm. 2017;9(1):87\u201393. https:\/\/doi.org\/10.5530\/jyp.2017.9.17.","journal-title":"J Young Pharm"},{"key":"1122_CR39","doi-asserted-by":"publisher","unstructured":"Jagtap PC, Prakya V, Bhise KS (2018) Design and development of controlled porosity osmotic tablets of Garcinia Indica extract. J Drug Deliv Ther. 8(4), 145\u2013150.\u00a0https:\/\/doi.org\/10.22270\/jddt.v8i4.1752.","DOI":"10.22270\/jddt.v8i4.1752"},{"issue":"1","key":"1122_CR40","first-page":"80","volume":"3","author":"S Edavalath","year":"2011","unstructured":"Edavalath S, Shivanand K, Prakasam K, Rao BP, Divakar G. Formulation development and optimization of controlled porosity osmotic pump tablets of diclofenac sodium. Int J Pharm Pharm Sci. 2011;3(1):80\u20137.","journal-title":"Int J Pharm Pharm Sci"},{"issue":"2","key":"1122_CR41","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1007\/s12247-009-9055-5","volume":"4","author":"R Bhanushali","year":"2009","unstructured":"Bhanushali R, Wakode R, Bajaj A. Monolithic osmotic tablets for controlled delivery of antihypertensive drug. J Pharm Innov. 2009;4(2):63\u201370. https:\/\/doi.org\/10.1007\/s12247-009-9055-5.","journal-title":"J Pharm Innov"},{"issue":"6","key":"1122_CR42","doi-asserted-by":"publisher","first-page":"782","DOI":"10.5829\/idosi.mejsr.2013.16.06.75176","volume":"16","author":"G Yadav","year":"2013","unstructured":"Yadav G, Bansal M, Thakur N, Sargam, and Khare, P. Multilayer tablets and their drug release kinetic models for oral controlled drug delivery system. Middle East J Sci Res. 2013;16(6):782\u201395. https:\/\/doi.org\/10.5829\/idosi.mejsr.2013.16.06.75176.","journal-title":"Middle East J Sci Res"},{"issue":"2","key":"1122_CR43","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1016\/j.healun.2011.11.016","volume":"31","author":"TH Kiser","year":"2012","unstructured":"Kiser TH, Fish DN, Zamora MR. Evaluation of valganciclovir pharmacokinetics in lung transplant recipients. J Heart Lung Transplant. 2012;31(2):159\u201366. https:\/\/doi.org\/10.1016\/j.healun.2011.11.016.","journal-title":"J Heart Lung Transplant"},{"key":"1122_CR44","doi-asserted-by":"publisher","unstructured":"Ning\u00a0M, Zhou\u00a0Y, Chen\u00a0G, Mei\u00a0X (2011) Preparation and in vitro\/in vivo evaluation of vinpocetine elementary osmotic pump system. Adv Pharmacol Sci.\u00a02011.\u00a0https:\/\/doi.org\/10.1155\/2011\/385469.","DOI":"10.1155\/2011\/385469"},{"issue":"4","key":"1122_CR45","doi-asserted-by":"publisher","first-page":"229","DOI":"10.4103\/2231-4040.104714","volume":"3","author":"SR Shahi","year":"2012","unstructured":"Shahi SR, Zadbuke NS, Gulecha B, Shivanikar SS, Shinde SB. Design and development of controlled porosity osmotic tablet of diltiazem hydrochloride. Journal of Advanced Pharmaceutical Technology and Research. 2012;3(4):229\u201336. https:\/\/doi.org\/10.4103\/2231-4040.104714.","journal-title":"Journal of Advanced Pharmaceutical Technology and Research"},{"issue":"4","key":"1122_CR46","doi-asserted-by":"publisher","first-page":"18","DOI":"10.5530\/ijper.48.4s.3","volume":"48","author":"V Suryadevara","year":"2014","unstructured":"Suryadevara V, Lankapalli SR, Rao Vejella UM, Mupparaju S, Chava SB. Formulation and evaluation of Losartan potassium osmotic controlled matrix tablets. Indian Journal of Pharmaceutical Education and Research. 2014;48(4):18\u201326. https:\/\/doi.org\/10.5530\/ijper.48.4s.3.","journal-title":"Indian Journal of Pharmaceutical Education and Research"},{"issue":"2","key":"1122_CR47","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1007\/s12247-016-9245-x","volume":"11","author":"A Banerjee","year":"2016","unstructured":"Banerjee A, Verma PRP, Gore S. Application of Box-Behnken design to optimize the osmotic drug delivery system of metoprolol succinate and its in vivo evaluation in beagle dogs. J Pharm Innov. 2016;11(2):120\u201333. https:\/\/doi.org\/10.1007\/s12247-016-9245-x.","journal-title":"J Pharm Innov"},{"issue":"7","key":"1122_CR48","doi-asserted-by":"publisher","first-page":"1079","DOI":"10.1080\/03639045.2019.1593441","volume":"45","author":"N Li","year":"2019","unstructured":"Li N, Fan L, Wu B, Dai G, Jiang C, Guo Y, Wang D. Preparation and in vitro\/in vivo evaluation of azilsartan osmotic pump tablets based on the preformulation investigation. Drug Dev Ind Pharm. 2019;45(7):1079\u201388. https:\/\/doi.org\/10.1080\/03639045.2019.1593441.","journal-title":"Drug Dev Ind Pharm"},{"issue":"3","key":"1122_CR49","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1016\/j.ajps.2018.05.009","volume":"14","author":"Y Li","year":"2019","unstructured":"Li Y, Pan H, Duan H, Chen J, Zhu Z, Fan J, Li P, Yang X, Pan W. Double-layered osmotic pump controlled release tablets of actarit: in vitro and in vivo evaluation. Asian J Pharm Sci. 2019;14(3):340\u20138. https:\/\/doi.org\/10.1016\/j.ajps.2018.05.009.","journal-title":"Asian J Pharm Sci"},{"issue":"4","key":"1122_CR50","doi-asserted-by":"publisher","first-page":"100","DOI":"10.7324\/JAPS.2020.104013","volume":"10","author":"HM Hashem","year":"2020","unstructured":"Hashem HM, Abdou AR, Taha NF, Mursi NM, Emara LH. Formulation and stability studies of metformin hydrochloride in a controlled porosity osmotic pump system. Journal of Applied Pharmaceutical Science. 2020;10(4):100\u201312. https:\/\/doi.org\/10.7324\/JAPS.2020.104013.","journal-title":"Journal of Applied Pharmaceutical Science"},{"issue":"3","key":"1122_CR51","first-page":"1","volume":"1","author":"SK Gupta","year":"2017","unstructured":"Gupta SK, Singhvi IJ, Ashawat MS, Sharma K, Shirsat M, Vaya R. Formulation and evaluation of extended release film coated tablet of divalproex sodium. Inventi Rapid. 2017;1(3):1\u20134.","journal-title":"Inventi Rapid"}],"container-title":["Drug Delivery and Translational Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13346-022-01122-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s13346-022-01122-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13346-022-01122-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,26]],"date-time":"2022-09-26T09:51:23Z","timestamp":1664185883000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s13346-022-01122-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,7]]},"references-count":51,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2022,11]]}},"alternative-id":["1122"],"URL":"https:\/\/doi.org\/10.1007\/s13346-022-01122-9","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-448422\/v1","asserted-by":"object"}]},"ISSN":["2190-393X","2190-3948"],"issn-type":[{"value":"2190-393X","type":"print"},{"value":"2190-3948","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,7]]},"assertion":[{"value":"22 January 2022","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 March 2022","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All animal experiments were approved by the Animal Ethical Committee of Wockhardt Research Center, Aurangabad. All institutional and national guidelines for the care and use of laboratory animals were followed.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interest"}}]}}