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Because the structure of the sebaceous glands in rabbit ears is similar to that of humans, rabbits were selected as experimental animal model. All animals were raised in the Laboratory Animal Center of Xiamen University (Natural light, constant temperature 24\u2103). In order to reduce the pain of the rabbits, they were euthanized by intravenous air injection before sampling. Clinical study was conducted by Xiang 'an Hospital of Xiamen University approved by Medical Ethics Committee of Xiamen University (Ethic Number: XDYX202305K24). All authors have read and followed the ARRIVE guidelines (https:arriveguidelines.org).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Prof. Dr. Ke-Jian Wang reports a patent ZL 202010101694.3 issued. Prof. Dr. Ming Chen reports two patents ZL 201610267764.6 and US 10,555,896 B2 issued.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclosure"}},{"value":"The authors declare no other conflict of interest.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}