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However, when integrated into implants, the system provided a sustained RB release of 75.84\u2009\u00b1\u20098.75% over 90 days. Cytotoxicity assays on PC-3 prostate cancer cells indicated an IC50 value of 1.19 \u00b5M for RB@PVA compared to 2.49 \u00b5M for free RB, effectively inhibiting cancer cell proliferation. This innovative drug delivery system, which incorporates a polymer matrix within an implantable device, represents a significant advancement in the sustained release of hydrosoluble drugs. 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