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All the animal experiments were kept to the National Regulation of China for Care and Use of Laboratory Animals. Both female BALB\/c mice and female C57BL\/6 mice were purchased from Beijing Huafukang Biotech Co., Ltd. (Beijing, China). The mice were housed in a ventilated, temperature-controlled, and illumination-controlled animal facility without specific pathogen (20\u2009\u00b1\u20092\u00a0\u00b0C; 50% \u00b1 10%; illumination, 8:00\u201320:00; dark, 20:00\u20138:00).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"All the authors read and approved the final version of the manuscript.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to publish"}},{"value":"All authors were employed by Beijing Youcare Kechuang Pharmaceutical Technology Co. Ltd. G.S. and H.Z. are inventors on a pending patent related to this work filed by Beijing Youcare Kechuang Pharmaceutical Technology Co. Ltd.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}