{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T05:24:47Z","timestamp":1777526687225,"version":"3.51.4"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T00:00:00Z","timestamp":1777334400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T00:00:00Z","timestamp":1777334400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100006769","name":"Russian Science Foundation","doi-asserted-by":"crossref","award":["24-73-10085"],"award-info":[{"award-number":["24-73-10085"]}],"id":[{"id":"10.13039\/501100006769","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Drug Deliv. and Transl. Res."],"DOI":"10.1007\/s13346-026-02135-4","type":"journal-article","created":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:30:34Z","timestamp":1777393834000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Cyclodextrin-based MOFs for oral delivery of fingolimod with enhanced pharmacokinetics"],"prefix":"10.1007","author":[{"given":"Irina","family":"Terekhova","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Garibyan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatiana","family":"Kalyagina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ekaterina","family":"Delyagina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatiana","family":"Sapozhnikova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergey","family":"Ivanov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,4,28]]},"reference":[{"key":"2135_CR1","doi-asserted-by":"publisher","first-page":"105415","DOI":"10.1016\/j.tifs.2025.105415","volume":"166","author":"X Dong","year":"2025","unstructured":"Dong X, Fan M, Zhao L, Wang K, Hu Z, Liu X. Recent advances in MOFs based hydrogels: From interactions, synthesis, and functionalization to food applications. Trends Food Sci Technol. 2025;166:105415. https:\/\/doi.org\/10.1016\/j.tifs.2025.105415.","journal-title":"Trends Food Sci Technol"},{"key":"2135_CR2","doi-asserted-by":"publisher","first-page":"671","DOI":"10.1134\/S0022476622050018","volume":"63","author":"M Agafonov","year":"2022","unstructured":"Agafonov M, Alexandrov E, Artyukhova N, et al. Metal-organic frameworks in Russia: from the synthesis and structure to functional properties and materials. J Struct Chem. 2022;63:671\u2013843. https:\/\/doi.org\/10.1134\/S0022476622050018.","journal-title":"J Struct Chem"},{"key":"2135_CR3","doi-asserted-by":"publisher","first-page":"102567","DOI":"10.1016\/j.rechem.2025.102567","volume":"17","author":"D Prasunaa","year":"2025","unstructured":"Prasunaa D, Rao A, Devi K, Erfan S, Reddy P, Babu B. A review on versatile roles of MOFs: Bridging biological applications and environmental technologies. Results Chem. 2025;17:102567. https:\/\/doi.org\/10.1016\/j.rechem.2025.102567.","journal-title":"Results Chem"},{"key":"2135_CR4","doi-asserted-by":"publisher","first-page":"217213","DOI":"10.1016\/j.ccr.2025.217213","volume":"549","author":"A Sheokand","year":"2026","unstructured":"Sheokand A, Sindhu S, Bulla M, Devi R, Dahiya R, Sanger A, Sisodia A, Mishra A, Kumar V. Transformative progress in MOF-based hybrid materials for supercapacitors and gas sensors: multifunctional platforms for sustainable technologies. Coord Chem Rev. 2026;549:217213. https:\/\/doi.org\/10.1016\/j.ccr.2025.217213.","journal-title":"Coord Chem Rev"},{"key":"2135_CR5","doi-asserted-by":"publisher","first-page":"122626","DOI":"10.1016\/j.ces.2025.122626","volume":"320","author":"S Khan","year":"2026","unstructured":"Khan S, Zhao M, Abbas F, Enujekwu F. Engineering strategies and structural-property relationships of metal-organic frameworks (MOFs) toward enhanced CO2. Chem Eng Sci. 2026;320:122626. https:\/\/doi.org\/10.1016\/j.ces.2025.122626.","journal-title":"Chem Eng Sci"},{"key":"2135_CR6","doi-asserted-by":"publisher","first-page":"116137","DOI":"10.1016\/j.ssc.2025.116137","volume":"405","author":"G Rana","year":"2025","unstructured":"Rana G, Alfifi F, Verma R, Rao S, Ramachandran D, Chauhan A, Jabir M, Ghotekar S. MOF-integrated magnetic nanomaterials for sustainable removal of pesticide residue wastes in aqueous systems. Solid State Commun. 2025;405:116137. https:\/\/doi.org\/10.1016\/j.ssc.2025.116137.","journal-title":"Solid State Commun"},{"key":"2135_CR7","doi-asserted-by":"publisher","first-page":"102926","DOI":"10.1016\/j.pmpp.2025.102926","volume":"140","author":"A Ishfaq","year":"2025","unstructured":"Ishfaq A, Shahid M, Hussain S, Shahzad T, Rasheed Y, Altihani F, Hashem M, Mahmood F. Harnessing metal-organic frameworks (MOFs) in agriculture: Mechanisms and application strategies for management of plant diseases. Physiol Mol Plant Pathol. 2025;140:102926. https:\/\/doi.org\/10.1016\/j.pmpp.2025.102926.","journal-title":"Physiol Mol Plant Pathol"},{"key":"2135_CR8","doi-asserted-by":"publisher","first-page":"1232","DOI":"10.1021\/cr200256v","volume":"112","author":"P Horcajada","year":"2012","unstructured":"Horcajada P, Gref R, Baati T, Allan P, Maurin G, Couvreur P, F\u00e9rey G, Morris R, Serre C. Metal\u2013Organic Frameworks in Biomedicine. Chem Rev. 2012;112:1232. https:\/\/doi.org\/10.1021\/cr200256v.","journal-title":"Chem Rev"},{"key":"2135_CR9","doi-asserted-by":"publisher","first-page":"9581","DOI":"10.1021\/jacs.8b04435","volume":"140","author":"S Rojas","year":"2018","unstructured":"Rojas S, Baati T, Njim L, Manchego L, Neffati F, Abdeljelil N, Saguem S, Serre C, Najjar M, Zakhama A, Horcajada P. Metal\u2013Organic Frameworks as Efficient Oral Detoxifying Agents. J Am Chem Soc. 2018;140:9581. https:\/\/doi.org\/10.1021\/jacs.8b04435.","journal-title":"J Am Chem Soc"},{"key":"2135_CR10","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1016\/j.ccr.2019.02.032","volume":"388","author":"S Rojas","year":"2019","unstructured":"Rojas S, Arenas-Vivo A, Horcajada P. Metal-organic frameworks: A novel platform for combined advanced therapies. Coord Chem Rev. 2019;388:202. https:\/\/doi.org\/10.1016\/j.ccr.2019.02.032.","journal-title":"Coord Chem Rev"},{"key":"2135_CR11","doi-asserted-by":"publisher","first-page":"137047","DOI":"10.1016\/j.ijbiomac.2024.137047","volume":"282","author":"H Zhu","year":"2024","unstructured":"Zhu H, Sun H, Dai J, Hao J, Zhou B. Chitosan-based hydrogels in cancer therapy: Drug and gene delivery, stimuli-responsive carriers, phototherapy and immunotherapy. Int J Biol Macromol. 2024;282:137047. https:\/\/doi.org\/10.1016\/j.ijbiomac.2024.137047.","journal-title":"Int J Biol Macromol"},{"key":"2135_CR12","doi-asserted-by":"publisher","first-page":"71","DOI":"10.3390\/pharmaceutics15010071","volume":"15","author":"E Delyagina","year":"2023","unstructured":"Delyagina E, Garibyan A, Agafonov M, Terekhova I. Regularities of encapsulation of tolfenamic acid and some other non-steroidal anti-inflammatory drugs in metal-organic framework based on \u03b3-cyclodextrin. Pharm. 2023;15:71. https:\/\/doi.org\/10.3390\/pharmaceutics15010071.","journal-title":"Pharm"},{"key":"2135_CR13","doi-asserted-by":"publisher","first-page":"110774","DOI":"10.1016\/j.msec.2020.110774","volume":"111","author":"I Kritskiy","year":"2020","unstructured":"Kritskiy I, Volkova T, Sapozhnikova T, Mazur A, Tolstoy P, Terekhova I. Methotrexate-loaded metal-organic frameworks on the basis of \u03b3-cyclodextrin: Design, characterization, in vitro and in vivo. Mater Sci Eng C. 2020;111:110774. https:\/\/doi.org\/10.1016\/j.msec.2020.110774.","journal-title":"Mater Sci Eng C"},{"key":"2135_CR14","doi-asserted-by":"publisher","first-page":"26647","DOI":"10.1039\/d5ra01665g","volume":"15","author":"M Ishfaq","year":"2025","unstructured":"Ishfaq M, Lateef D, Ashraf Z, Sajjad M, Owais M, Shoukat W, Mohsin M, Muhammad Ibrahim, Verpoort F, Chughtai A. Zirconium-based MOFs as pH-responsive drug delivery systems: encapsulation and release profiles of ciprofloxacin. RSC Adv. 2025;15:26647\u201359. https:\/\/doi.org\/10.1039\/d5ra01665g.","journal-title":"RSC Adv"},{"key":"2135_CR15","doi-asserted-by":"publisher","first-page":"103670","DOI":"10.1016\/j.cis.2025.103670","volume":"346","author":"K Arezou","year":"2025","unstructured":"Arezou K, Rezvani-Ghalhari M, Sani M, McClements D. Supramolecular cyclodextrin-based metal-organic frameworks (MOFs): Advanced food applications. Adv Colloid Interface Sci. 2025;346:103670. https:\/\/doi.org\/10.1016\/j.cis.2025.103670.","journal-title":"Adv Colloid Interface Sci"},{"key":"2135_CR16","doi-asserted-by":"publisher","DOI":"10.1080\/14786419.2025.2581222","author":"E-ZA El-Aziz","year":"2025","unstructured":"El-Aziz E-ZA, Dawood F, Abdel-Baseer Tohamy Abd El-Aziz A, Ali M, Ahmed M, Elbeshbeishy H, Thabit R, Welson R, Hamad N D. Protective effects of whey camel milk proteins conjugate with metal\u2013organic frameworks (MOF) as antimicrobial and against cobalt-induced chloragogen cell toxicity in earthworms. Nat Prod Res. 2025. https:\/\/doi.org\/10.1080\/14786419.2025.2581222.","journal-title":"Nat Prod Res"},{"key":"2135_CR17","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1038\/s41699-025-00603-y","volume":"9","author":"S Y\u00fccer","year":"2025","unstructured":"Y\u00fccer S, Sarac B, Ciftci F. 2D MOF structure, electrochemical biosensing in bioelectronic applications. Npj 2D Mater Appl. 2025;9:81. https:\/\/doi.org\/10.1038\/s41699-025-00603-y.","journal-title":"Npj 2D Mater Appl"},{"key":"2135_CR18","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1007\/s42058-025-00195-y","volume":"8","author":"S Amini","year":"2025","unstructured":"Amini S, Baniasadipour B, Bagheri F, Berenji M. Recent advances in magnetic resonance imaging using metal-organic frameworks. Chin J Acad Radiol. 2025;8:173. https:\/\/doi.org\/10.1007\/s42058-025-00195-y.","journal-title":"Chin J Acad Radiol"},{"key":"2135_CR19","doi-asserted-by":"publisher","first-page":"5571","DOI":"10.1039\/D4NR03898C","volume":"17","author":"Y Jing","year":"2025","unstructured":"Jing Y, Liu X, Zhu Y, Wu L, Nong W. Metal\u2013organic framework microneedles for precision transdermal drug delivery: design strategy and therapeutic potential. Nanoscale. 2025;17:5571\u2013604. https:\/\/doi.org\/10.1039\/D4NR03898C.","journal-title":"Nanoscale"},{"key":"2135_CR20","doi-asserted-by":"publisher","first-page":"22188","DOI":"10.1021\/acsami.9b06472","volume":"11","author":"S Rojas","year":"2019","unstructured":"Rojas S, Guillou N, Horcajada P. Ti-Based nanoMOF as an Efficient Oral Therapeutic Agent. ACS Appl Mater Interfaces. 2019;11:22188. https:\/\/doi.org\/10.1021\/acsami.9b06472.","journal-title":"ACS Appl Mater Interfaces"},{"key":"2135_CR21","doi-asserted-by":"publisher","first-page":"8630","DOI":"10.1002\/anie.201002343","volume":"49","author":"R Smaldone","year":"2010","unstructured":"Smaldone R, Forgan R, Furukawa H, Gassensmith J, Slawin A, Yaghi O, Stoddart J. Metal\u2013organic frameworks from edible natural products. Angew Chem Int Ed. 2010;49:8630. https:\/\/doi.org\/10.1002\/anie.201002343.","journal-title":"Angew Chem Int Ed"},{"key":"2135_CR22","doi-asserted-by":"publisher","first-page":"34095","DOI":"10.1021\/acsami.0c08594","volume":"30","author":"H Li","year":"2021","unstructured":"Li H, Shi L, Li C, Fu X, Huang Q, Zhang B. Metal\u2013organic framework based on \u03b1-cyclodextrin gives high ethylene gas adsorption capacity and storage stability. ACS Appl Mater Interfaces. 2021;30:34095\u2013104. https:\/\/doi.org\/10.1021\/acsami.0c08594.","journal-title":"ACS Appl Mater Interfaces"},{"key":"2135_CR23","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1016\/j.poly.2018.11.043","volume":"195","author":"L Zha","year":"2019","unstructured":"Zha L, Shang M, Qiu M, Zhang H, Su Y. Process intensification of mixing and chemical modification for polymer solutions in microreactors based on gas-liquid two-phase flow. Chem Eng Sci. 2019;195:62\u201373. https:\/\/doi.org\/10.1016\/j.poly.2018.11.043.","journal-title":"Chem Eng Sci"},{"key":"2135_CR24","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1016\/j.molstruc.2015.08.020","volume":"1101","author":"J-Q Sha","year":"2015","unstructured":"Sha J-Q, Wu L-H, Li S-X, Yang X-N, Zhang Y, Zhang Q-N, Zhu P-P. Synthesis and structure of new carbohydrate metaleorganic frameworks and inclusion complexes. J Mol Struct. 2015;1101:14\u201320. https:\/\/doi.org\/10.1016\/j.molstruc.2015.08.020.","journal-title":"J Mol Struct"},{"issue":"3","key":"2135_CR25","first-page":"236","volume":"8","author":"FJ Dumont","year":"2005","unstructured":"Dumont FJ. Fingolimod. Mitsubishi Pharma\/Novartis IDrugs. 2005;8(3):236\u201353. PMID: 15772896.","journal-title":"Mitsubishi Pharma\/Novartis IDrugs"},{"key":"2135_CR26","doi-asserted-by":"publisher","first-page":"8192","DOI":"10.3390\/ijms23158192","volume":"23","author":"T Rupp","year":"2022","unstructured":"Rupp T, Debasly S, Genest L, Froget G, Castagn\u00e9 V. Therapeutic potential of fingolimod and dimethyl fumarate in non-small cell lung cancer preclinical models. Int J Mol Sci. 2022;23:8192. https:\/\/doi.org\/10.3390\/ijms23158192.","journal-title":"Int J Mol Sci"},{"key":"2135_CR27","doi-asserted-by":"publisher","first-page":"e01039","DOI":"10.1002\/prp2.1039","volume":"11","author":"S Teymouri","year":"2023","unstructured":"Teymouri S, Kaleybar S, Hejazian S, Hejazian S, Ansarin K, Ardalan M, Vahed S. The effect of Fingolimod on patients with moderate to severe COVID-19. Pharmacol Res Perspect. 2023;11:e01039. https:\/\/doi.org\/10.1002\/prp2.1039.","journal-title":"Pharmacol Res Perspect"},{"key":"2135_CR28","doi-asserted-by":"publisher","first-page":"109","DOI":"10.34172\/bi.2022.23383","volume":"13","author":"S Gholizadeh","year":"2022","unstructured":"Gholizadeh S, Haghaei H, Karami H, Soltani S, Zakariazadeh M, Shokri J. Mode of binding, kinetic and thermodynamic properties of a lipid-like drug (Fingolimod) interacting with Human Serum Albumin. Bioimpacts. 2022;13:109\u201321. https:\/\/doi.org\/10.34172\/bi.2022.23383.","journal-title":"Bioimpacts"},{"key":"2135_CR29","unstructured":"Abraham J, Rajhans S, Buch T. (2015) Pharmaceutical composition of fingolimod Patent WO2015104666A2. https:\/\/patents.google.com\/patent\/WO2015104666A2\/en"},{"key":"2135_CR30","first-page":"215","volume":"3","author":"T Kumar","year":"2013","unstructured":"Kumar T, Nirmala, Harikumar S. Various techniques enhancing bioavailabilty of poorly water soluble drugs. J Drug Deliv Ther. 2013;3:215\u201321.","journal-title":"J Drug Deliv Ther"},{"key":"2135_CR31","first-page":"15","volume":"11","author":"J Katakawa","year":"2011","unstructured":"Katakawa J, Minami H, Fujita T, Sano Y. Concentric nano-sized vesicle formation by immunosuppressant FTY720 revealed with small-angle X-ray scattering using synchrotron radiation source. J Biol Macromol. 2011;11:15\u201322.","journal-title":"J Biol Macromol"},{"key":"2135_CR32","doi-asserted-by":"publisher","first-page":"17962","DOI":"10.1039\/C3CP53148A","volume":"15","author":"J Swain","year":"2013","unstructured":"Swain J, Mohapatra M, Borkar S, Aidhen I, Mishra A. Study of aqueous phase aggregation of FTY720 (fingolimod hydrochloride) and its effect on DMPC liposomes using fluorescent molecular probes. PCCP. 2013;15:17962\u201370. https:\/\/doi.org\/10.1039\/C3CP53148A.","journal-title":"PCCP"},{"key":"2135_CR33","doi-asserted-by":"publisher","first-page":"3371","DOI":"10.1021\/acsabm.2c00349","volume":"5","author":"R Miranda","year":"2022","unstructured":"Miranda R, Ferreira N, de Souza E, Lins P, Ferreira L, Kr\u00fcger A, de Oliveira Cardoso V, Durigon E, Wrenger C, Zucolotto V. Modulating Fingolimod (FTY720) Anti-SARS-CoV-2 Activity Using a PLGA-Based Drug Delivery System. ACS Appl Bio Mater. 2022;5:3371\u201383. https:\/\/doi.org\/10.1021\/acsabm.2c00349.","journal-title":"ACS Appl Bio Mater"},{"key":"2135_CR34","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1002\/jbm.b.33862","volume":"106","author":"D Bowers","year":"2017","unstructured":"Bowers D, Olingy C, Chhabra P, Langman L, Merrill P, Linhart Ri, Tanes M, Lin D, Brayman K, Botchwey E. An engineered macroencapsulation membrane releasing FTY720 to precondition pancreatic islet transplantation. J Biomed Mater Res B. 2017;106:555\u201368. https:\/\/doi.org\/10.1002\/jbm.b.33862.","journal-title":"J Biomed Mater Res B"},{"key":"2135_CR35","doi-asserted-by":"publisher","unstructured":"El-hoshoudy A, Dessouky S, Al-Sabagh A, Betiha M. (2016) Evaluation of solution and rheological properties for hydrophobically associated polyacrylamide copolymer as a promised enhanced oil recovery candidate. Egypt J Pet 23 https:\/\/doi.org\/10.1016\/j.poly.2016.10.012","DOI":"10.1016\/j.poly.2016.10.012"},{"key":"2135_CR36","doi-asserted-by":"publisher","first-page":"100727","DOI":"10.1016\/j.carpta.2025.100727","volume":"9","author":"T Sogore","year":"2025","unstructured":"Sogore T, Guo M, Sun N, Jiang D, Liu D, Shen M, Ding T. Cyclodextrin metal-organic framework for efficient adsorption of lithium phenyl-2,4,6-trimethylbenzoylphosphinate (LAP) residues from cultured meat. Carbohydr Polym Technol Appl. 2025;9:100727. https:\/\/doi.org\/10.1016\/j.carpta.2025.100727.","journal-title":"Carbohydr Polym Technol Appl"},{"key":"2135_CR37","doi-asserted-by":"publisher","first-page":"3101829","DOI":"10.1002\/adfm.202101829","volume":"9","author":"S Hajra","year":"2021","unstructured":"Hajra S, Sahu M, Padhan A, Lee I, Yi D, Alagarsamy P, Nanda S, Kim H. A Green metal\u2013organic framework-cyclodextrin MOF: A novel multifunctional material based triboelectric nanogenerator for highly efficient mechanical energy harvesting. Adv Funct Mater. 2021;9:3101829. https:\/\/doi.org\/10.1002\/adfm.202101829.","journal-title":"Adv Funct Mater"},{"key":"2135_CR38","doi-asserted-by":"publisher","first-page":"e30349","DOI":"10.1016\/j.heliyon.2024.e30349","volume":"10","author":"P Sadeh","year":"2024","unstructured":"Sadeh P, Zeinali S, Rastegari B, Najafipour I. Functionalization of \u03b2-cyclodextrin metal-organic frameworks with gelatin and glutamine for drug delivery of curcumin to cancerous cells. Heliyon. 2024;10:e30349. https:\/\/doi.org\/10.1016\/j.heliyon.2024.e30349.","journal-title":"Heliyon"},{"key":"2135_CR39","doi-asserted-by":"publisher","first-page":"127839","DOI":"10.1016\/j.foodchem.2020.127839","volume":"338","author":"Z Hu","year":"2021","unstructured":"Hu Z, Li S, Wang S, Zhang B, Huang Q. Encapsulation of menthol into cyclodextrin metal-organic frameworks: Preparation, structure characterization and evaluation of complexing capacity. Food Chem. 2021;338:127839. https:\/\/doi.org\/10.1016\/j.foodchem.2020.127839.","journal-title":"Food Chem"},{"key":"2135_CR40","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1016\/j.carbpol.2019.04.037","volume":"216","author":"I Kritskiy","year":"2019","unstructured":"Kritskiy I, Volkova T, Surov A, Terekhova I. \u03b3-Cyclodextrin-metal organic frameworks as efficient microcontainers for encapsulation of leflunomide and acceleration of its transformation into teriflunomide. Carbohydr Polym. 2019;216:224\u201330. https:\/\/doi.org\/10.1016\/j.carbpol.2019.04.037.","journal-title":"Carbohydr Polym"},{"key":"2135_CR41","doi-asserted-by":"publisher","first-page":"110774","DOI":"10.1016\/j.msec.2020.110774","volume":"111","author":"I Kritskiy","year":"2020","unstructured":"Kritskiy I, Volkova T, Sapozhnikova T, Mazur A, Tolstoy P, Terekhova I. Methotrexate-loaded metal-organic frameworks on the basis of \u03b3-cyclodextrin: Design, characterization, in vitr and in vivo. Mater Sci Eng C. 2020;111:110774. https:\/\/doi.org\/10.1016\/j.msec.2020.110774.","journal-title":"Mater Sci Eng C"},{"key":"2135_CR42","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1016\/j.jiec.2021.10.028","volume":"106","author":"M Agafonov","year":"2022","unstructured":"Agafonov M, Garibyan A, Terekhova I. Improving pharmacologically relevant properties of sulfasalazine loaded in \u03b3-cyclodextrin-based metal organic framework. J Ind Eng Chem. 2022;106:189\u201397. https:\/\/doi.org\/10.1016\/j.jiec.2021.10.028.","journal-title":"J Ind Eng Chem"},{"key":"2135_CR43","doi-asserted-by":"publisher","first-page":"71","DOI":"10.3390\/pharmaceutics15010071","volume":"15","author":"E Delyagina","year":"2022","unstructured":"Delyagina E, Garibyan A, Agafonov M, Terekhova I. Regularities of Encapsulation of Tolfenamic Acid and Some Other Non-Steroidal Anti-Inflammatory Drugs in Metal-Organic Framework Based on \u03b3-Cyclodextrin. Pharm. 2022;15:71. https:\/\/doi.org\/10.3390\/pharmaceutics15010071.","journal-title":"Pharm"},{"key":"2135_CR44","doi-asserted-by":"publisher","first-page":"74","DOI":"10.3390\/recycling9050074","volume":"9","author":"S-F Wu","year":"2024","unstructured":"Wu S-F, Cheng H-M. Adsorptive removal of phosphate from water using aluminum terephthalate (MIL-53) metal\u2013organic framework and its hollow fiber module. Recycling. 2024;9:74. https:\/\/doi.org\/10.3390\/recycling9050074.","journal-title":"Recycling"},{"key":"2135_CR45","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1590\/S0104-66322011000200014","volume":"28","author":"J Piccin","year":"2011","unstructured":"Piccin J, Dotto G, Pinto L. Adsorption isotherms and thermochemical data of FD&C red \u2116 40 binding by chitosan. Braz J Chem Eng. 2011;28:295\u2013304.","journal-title":"Braz J Chem Eng"},{"key":"2135_CR46","doi-asserted-by":"publisher","first-page":"107541","DOI":"10.1016\/j.jddst.2025.107541","volume":"114","author":"Z Yeganeh","year":"2025","unstructured":"Yeganeh Z, Oveissi F, Dayani L, Aliomrani M, Taheri A. Preparation and evaluation of pomegranate seed oil nanoemulsions for delivery of fingolimod hydrochloride in multiple sclerosis treatment. J Drug Deliv Sci Technol. 2025;114:107541. https:\/\/doi.org\/10.1016\/j.jddst.2025.107541.","journal-title":"J Drug Deliv Sci Technol"},{"key":"2135_CR47","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/j.jpba.2015.02.018","volume":"109","author":"J-R Wang","year":"2015","unstructured":"Wang J-R, Li S, Zhu B, Mei X. Insight into the conformational polymorph transformation of a block-buster multiple sclerosis drug fingolimod hydrochloride (FTY 720). J Pharm Biomed Anal. 2015;109:45\u201351. https:\/\/doi.org\/10.1016\/j.jpba.2015.02.018.","journal-title":"J Pharm Biomed Anal"},{"key":"2135_CR48","doi-asserted-by":"publisher","first-page":"106982","DOI":"10.1016\/j.jddst.2025.106982","volume":"110","author":"P Wang","year":"2025","unstructured":"Wang P, Ma Y, Wei L, Miao L, Wang X, Chen W. Enhancing the solubility and bioavailability of bazedoxifene with varying \u03b3-cyclodextrin metal-organic frameworks (\u03b3-CD-MOFs) as delivery vehicles. J Drug Deliv Sci Technol. 2025;110:106982. https:\/\/doi.org\/10.1016\/j.jddst.2025.106982.","journal-title":"J Drug Deliv Sci Technol"},{"key":"2135_CR49","doi-asserted-by":"publisher","first-page":"3504","DOI":"10.1134\/S0036024424703096","volume":"98","author":"A Garibyan","year":"2024","unstructured":"Garibyan A, Delyagina E, Terekhova I. Solubilization of the new generation immunomodulator fingolimod using natural, modified, and polymeric cyclodextrins. Russ J Phys Chem A. 2024;98:3504\u20138. https:\/\/doi.org\/10.1134\/S0036024424703096.","journal-title":"Russ J Phys Chem A"}],"container-title":["Drug Delivery and Translational Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13346-026-02135-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s13346-026-02135-4","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13346-026-02135-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:30:37Z","timestamp":1777393837000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s13346-026-02135-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,28]]},"references-count":49,"alternative-id":["2135"],"URL":"https:\/\/doi.org\/10.1007\/s13346-026-02135-4","relation":{},"ISSN":["2190-393X","2190-3948"],"issn-type":[{"value":"2190-393X","type":"print"},{"value":"2190-3948","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,28]]},"assertion":[{"value":"21 January 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 April 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 April 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interests"}}]}}