{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T01:42:14Z","timestamp":1772847734739,"version":"3.50.1"},"reference-count":55,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2021,2,27]],"date-time":"2021-02-27T00:00:00Z","timestamp":1614384000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,2,27]],"date-time":"2021-02-27T00:00:00Z","timestamp":1614384000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"name":"Science and Technology Support Plan Project of Tianshui","award":["2018-FZJHK-7879"],"award-info":[{"award-number":["2018-FZJHK-7879"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["31960268"],"award-info":[{"award-number":["31960268"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Appl Genetics"],"published-print":{"date-parts":[[2021,5]]},"DOI":"10.1007\/s13353-021-00624-5","type":"journal-article","created":{"date-parts":[[2021,2,27]],"date-time":"2021-02-27T13:02:45Z","timestamp":1614430965000},"page":"307-317","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Response of the ileum transcriptome to probiotic and fructo-oligosaccharides in Taiping chicken"],"prefix":"10.1007","volume":"62","author":[{"given":"Lintong","family":"Luo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fang","family":"Ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qianning","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,2,27]]},"reference":[{"key":"624_CR1","first-page":"61","volume":"5","author":"A Ashayerizadeh","year":"2011","unstructured":"Ashayerizadeh A, Dabiri N, Mirzadeh KH, Ghorbani MR (2011) Effects of dietary inclusion of several biological feed additives on growth response of broiler chickens. Cell Anim Biol 5:61\u201365 https:\/\/www.researchgate.net\/publication\/233756218","journal-title":"Cell Anim Biol"},{"key":"624_CR2","doi-asserted-by":"publisher","first-page":"675","DOI":"10.1146\/annurev.immunol.15.1.675","volume":"15","author":"M Baggiolini","year":"1997","unstructured":"Baggiolini M, Dewald B, Moser B (1997) Human chemokines: an update. Annu Rev Immunol 15:675\u2013705. https:\/\/doi.org\/10.1146\/annurev.immunol.15.1.675","journal-title":"Annu Rev Immunol"},{"key":"624_CR3","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1017\/S0043933909000221","volume":"65","author":"B Besbes","year":"2009","unstructured":"Besbes B (2009) Genotype evaluation and breeding of poultry for performance under suboptimal village conditions. World\u2019s Poultry Sci J 65:260\u2013271. https:\/\/doi.org\/10.1017\/S0043933909000221","journal-title":"World\u2019s Poultry Sci J"},{"key":"624_CR4","doi-asserted-by":"publisher","first-page":"e1003015","DOI":"10.1080\/2162402X.2014.1003015","volume":"4","author":"N Bonnefoy","year":"2015","unstructured":"Bonnefoy N, Bastid J, Alberici G, Bensussan A, Eliaou JF (2015) CD39: A complementary target to immune checkpoints to counteract tumor-mediated immunosuppression. Oncoimmunology 4:e1003015. https:\/\/doi.org\/10.1080\/2162402X.2014.1003015","journal-title":"Oncoimmunology"},{"key":"624_CR5","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1186\/1475-2891-5-8","volume":"5","author":"Y Bouhnik","year":"2006","unstructured":"Bouhnik Y, Raskine L, Simoneau G, Paineau D, Bornet F (2006) The capacity of short-chain fructo-oligosaccharides to stimulate faecal bifidobacteria: a dose-response relationship study in healthy humans. Nutr J 5:8. https:\/\/doi.org\/10.1186\/1475-2891-5-8","journal-title":"Nutr J"},{"key":"624_CR6","doi-asserted-by":"publisher","first-page":"1098","DOI":"10.1002\/mnfr.201300497","volume":"58","author":"F Capit\u00e1n-Ca\u00f1adas","year":"2014","unstructured":"Capit\u00e1n-Ca\u00f1adas F, Ortega-Gonz\u00e1lez M, Guadix E, Zarzuelo A, Su\u00e1rez MD, de Medina FS, Mart\u00ednez-Augustin O (2014) Prebiotic oligosaccharides directly modulate proinflammatory cytokine production in monocytes via activation of TLR4. Mol Nutr Food Res 58:1098\u20131110. https:\/\/doi.org\/10.1002\/mnfr.201300497","journal-title":"Mol Nutr Food Res"},{"key":"624_CR7","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1016\/j.dci.2006.04.001","volume":"31","author":"JH Cheeseman","year":"2007","unstructured":"Cheeseman JH, Kaiser MG, Ciraci C, Kaiser P, Lamont SJ (2007) Breed effect on early cytokine mRNA expression in spleen and cecum of chickens with and without Salmonella enteritidis infection. Dev Comp Immunol 31:52\u201360. https:\/\/doi.org\/10.1016\/j.dci.2006.04.001","journal-title":"Dev Comp Immunol"},{"key":"624_CR8","doi-asserted-by":"publisher","first-page":"i884","DOI":"10.1093\/bioinformatics\/bty560","volume":"34","author":"S Chen","year":"2018","unstructured":"Chen S, Zhou Y, Chen Y, Gu J (2018) fastp: an ultra-fast all-in-one FASTQ preprocessor. Bioinformatics 34:i884\u2013i890. https:\/\/doi.org\/10.1093\/bioinformatics\/bty560","journal-title":"Bioinformatics"},{"key":"624_CR9","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1111\/j.1365-2443.2008.01197.x","volume":"13","author":"YL Chen","year":"2008","unstructured":"Chen YL, Lin DW, Chang ZF (2008) Identification of a putative human mitochondrial thymidine monophosphate kinase associated with monocytic\/macrophage terminal differentiation. Genes Cells 13:679\u2013689. https:\/\/doi.org\/10.1111\/j.1365-2443.2008.01197.x","journal-title":"Genes Cells"},{"key":"624_CR10","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1165\/rcmb.2014-0002OC","volume":"52","author":"CA Downs","year":"2015","unstructured":"Downs CA, Kreiner LH, Johnson NM, Brown LA, Helms MN (2015) Receptor for advanced glycation end-products regulates lung fluid balance via protein kinase C\u2013gp91phox signaling to epithelial sodium channels. Am J Respir Cell Mol Biol 52:75\u201387. https:\/\/doi.org\/10.1165\/rcmb.2014-0002OC","journal-title":"Am J Respir Cell Mol Biol"},{"key":"624_CR11","unstructured":"Eldiwany R, Soliman M, Sugawara S, Breitwieser F, Skaist A, Coggiano C, Sangal N, Chattergoon M, Bailey JR, Siliciano RF (2018) CMPK2 and BCL-G are associated with type 1 interferon\u2013induced HIV restriction in humans. Science Advances 4:eaat0843. https:\/\/doi.org\/ 10.1126\/sciadv.aat0843"},{"key":"624_CR12","doi-asserted-by":"publisher","first-page":"610","DOI":"10.1038\/s41586-018-0238-4","volume":"558","author":"AS Gizzi","year":"2018","unstructured":"Gizzi AS, Grove TL, Arnold JJ, Jose J, Jangra RK, Garforth SJ, Du Q, Cahill SM, Dulyaninova NG, Love JD (2018b) A naturally occurring antiviral ribonucleotide encoded by the human genome. Nature 558:610\u2013614. https:\/\/doi.org\/10.1038\/s41586-018-0238-4","journal-title":"Nature"},{"key":"624_CR13","doi-asserted-by":"publisher","first-page":"eaat0843","DOI":"10.1126\/sciadv.aat0843","volume":"4","author":"R Gizzi","year":"2018","unstructured":"Gizzi R, Soliman M, Sugawara S, Breitwieser F, Skaist A, Coggiano C, Sangal N, Chattergoon M, Bailey JR, Siliciano RF (2018a) CMPK2 and BCL-G are associated with type 1 interferon\u2013induced HIV restriction in humans. Sci Adv 4:eaat0843. https:\/\/doi.org\/10.1126\/sciadv.aat0843","journal-title":"Sci Adv"},{"key":"624_CR14","doi-asserted-by":"publisher","first-page":"851","DOI":"10.1016\/j.tim.2017.05.004","volume":"25","author":"R Gresse","year":"2017","unstructured":"Gresse R, Chaucheyras-Durand F, Fleury MA, Van de Wiele T, Forano E, Blanquet-Diot S (2017) Gut microbiota dysbiosis in postweaning piglets: understanding the keys to health. Trends Microbiol 25:851\u2013873. https:\/\/doi.org\/10.1016\/j.tim.2017.05.004","journal-title":"Trends Microbiol"},{"key":"624_CR15","doi-asserted-by":"publisher","first-page":"573676","DOI":"10.3389\/fphys.2020.573676","volume":"11","author":"L Guo","year":"2020","unstructured":"Guo L, Huang W, Tong F, Chen X, Cao S, Xu H, Luo W, Li Z, Nie Q (2020) Whole Transcriptome analysis of chicken bursa reveals candidate gene that enhances the host\u2019s immune response to coccidiosis. Front Physiol 11:573676. https:\/\/doi.org\/10.3389\/fphys.2020.573676","journal-title":"Front Physiol"},{"key":"624_CR16","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1038\/nbt0510-421","volume":"28","author":"BJ Haas","year":"2010","unstructured":"Haas BJ, Zody MC (2010) Advancing RNA-Seq analysis. Nature Biotechnol 28:421\u2013423. https:\/\/doi.org\/10.1038\/nbt0510-421","journal-title":"Nature Biotechnol"},{"key":"624_CR17","doi-asserted-by":"publisher","first-page":"758","DOI":"10.1271\/bbb.67.758","volume":"67","author":"A Hosono","year":"2003","unstructured":"Hosono A, Ozawa A, Kato R, Ohnishi Y, Nakanishi Y, Kimura T, Nakamura R (2003) Dietary fructooligosaccharides induce immunoregulation of intestinal IgA secretion by murine Peyer\u2019s patch cells. Biosci Biotechnol Biochem 67:758\u2013764. https:\/\/doi.org\/10.1271\/bbb.67.758","journal-title":"Biosci Biotechnol Biochem"},{"key":"624_CR18","doi-asserted-by":"publisher","first-page":"2228","DOI":"10.3390\/ani10122228","volume":"10","author":"K Jin","year":"2020","unstructured":"Jin K, Zhou J, Zuo Q, Song J, Zhang Y, Chang G, Chen G, Li B (2020) Gallus gallus transcriptome sequencing and comparative analysis of amphoteric ESCs and PGCs in chicken. Animals 10:2228. https:\/\/doi.org\/10.3390\/ani10122228","journal-title":"Animals"},{"key":"624_CR19","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1093\/nar\/28.1.27","volume":"28","author":"M Kanehisa","year":"2000","unstructured":"Kanehisa M, Goto S (2000) KEGG: Kyoto encyclopedia of genes and genomes. Nucleic Acids Res 28:27\u201330. https:\/\/doi.org\/10.1093\/nar\/28.1.27","journal-title":"Nucleic Acids Res"},{"key":"624_CR20","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1136\/aim.2009.000596","volume":"13","author":"G Kelly","year":"2008","unstructured":"Kelly G (2008) Inulin-type prebiotics--a review: part 1. Altern Med Rev 13:315\u2013329. https:\/\/doi.org\/10.1136\/aim.2009.000596","journal-title":"Altern Med Rev"},{"key":"624_CR21","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/BF00982231","volume":"27","author":"JO Khobondo","year":"2015","unstructured":"Khobondo JO, Muasya TK, Miyumo S, Okeno TO, Wasike CB, Mwakubambanya R, Kingori AM, Kahi AK (2015) Genetic and nutrition development of indigenous chicken in Africa. Livestock Res Rural Dev 27:1\u201322. https:\/\/doi.org\/10.1007\/BF00982231","journal-title":"Livestock Res Rural Dev"},{"key":"624_CR22","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1038\/nmeth.3317","volume":"12","author":"D Kim","year":"2015","unstructured":"Kim D, Langmead B, Salzberg SL (2015) HISAT: a fast spliced aligner with low memory requirements. Nat Methods 12:357. https:\/\/doi.org\/10.1038\/nmeth.3317","journal-title":"Nat Methods"},{"key":"624_CR23","doi-asserted-by":"publisher","first-page":"75","DOI":"10.3382\/ps.2010-00732","volume":"90","author":"GB Kim","year":"2011","unstructured":"Kim GB, Seo YM, Kim CH, Paik IK (2011) Effect of dietary prebiotic supplementation on the performance, intestinal microflora, and immune response of broilers. Poultry Sci 90:75\u201382. https:\/\/doi.org\/10.3382\/ps.2010-00732","journal-title":"Poultry Sci"},{"key":"624_CR24","doi-asserted-by":"publisher","first-page":"1158","DOI":"10.1053\/j.gastro.2012.09.008","volume":"143","author":"P Kubes","year":"2012","unstructured":"Kubes P, Mehal WZ (2012) Sterile inflammation in the liver. Gastroenterology 143:1158\u20131172. https:\/\/doi.org\/10.1053\/j.gastro.2012.09.008","journal-title":"Gastroenterology"},{"key":"624_CR25","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1038\/nmeth.1923","volume":"9","author":"B Langmead","year":"2012","unstructured":"Langmead B, Salzberg SL (2012) Fast gapped-read alignment with Bowtie 2. Nat Methods 9:357\u2013359. https:\/\/doi.org\/10.1038\/nmeth.1923","journal-title":"Nat Methods"},{"key":"624_CR26","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1016\/j.bbagen.2004.09.006","volume":"1721","author":"DB Leal","year":"2005","unstructured":"Leal DB, Streher CA, Neu TN, Bittencourt FP, Leal CA, da Silva JE, Morsch VM, Schetinger MR (2005) Characterization of NTPDase (NTPDase1; ecto-apyrase; ecto-diphosphohydrolase; CD39; EC 3.6.1.5) activity in human lymphocytes. Biochim Biophys Acta 1721:9\u201315. https:\/\/doi.org\/10.1016\/j.bbagen.2004.09.006","journal-title":"Biochim Biophys Acta"},{"key":"624_CR27","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1142\/S1682648519300016","volume":"45","author":"CC Lee","year":"2019","unstructured":"Lee CC, Tung CY, Wu CC, Lin TL (2019) Avian innate immunity with an emphasis on chicken melanoma differentiation-associated gene 5 (MDA5). Taiwan Veterinary J 45:43\u201355. https:\/\/doi.org\/10.1142\/S1682648519300016","journal-title":"Taiwan Veterinary J"},{"key":"624_CR28","doi-asserted-by":"publisher","first-page":"8008","DOI":"10.1038\/s41598-017-06712-z","volume":"7","author":"Q Li","year":"2017","unstructured":"Li Q, Lin Y, Wang S, Zhang L, Guo L (2017) GLP-1 inhibits high-glucose-induced oxidative injury of vascular endothelial cells. Sci Rep 7:8008. https:\/\/doi.org\/10.1038\/s41598-017-06712-z","journal-title":"Sci Rep"},{"key":"624_CR29","doi-asserted-by":"publisher","first-page":"64","DOI":"10.5194\/aab-51-64-2008","volume":"51","author":"X Li","year":"2008","unstructured":"Li X, Qiang L, Liu L, Xu CH (2008) Effects of supplementation of fructooligosaccharide and\/or Bacillus subtilis to diets on performance and on intestinal microflora in broilers. Archive Tierzucht 51:64\u201370. https:\/\/doi.org\/10.5194\/aab-51-64-2008","journal-title":"Archive Tierzucht"},{"key":"624_CR30","doi-asserted-by":"publisher","first-page":"3384","DOI":"10.2527\/jas.2015-8902","volume":"93","author":"X Liu","year":"2015","unstructured":"Liu X, Cao G, Wang Q, Yao X, Fang B (2015) The effect of Bacillus coagulans-fermented and nonfermented Ginkgo biloba on the immunity status of broiler chickens. J Anim Sci 93:3384\u20133394. https:\/\/doi.org\/10.2527\/jas.2015-8902","journal-title":"J Anim Sci"},{"key":"624_CR31","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1006\/meth.2001.1262","volume":"25","author":"KJ Livak","year":"2001","unstructured":"Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2-\u0394\u0394Ct method. Methods 25:402\u2013408. https:\/\/doi.org\/10.1006\/meth.2001.1262","journal-title":"Methods"},{"key":"624_CR32","doi-asserted-by":"publisher","first-page":"550","DOI":"10.1186\/s13059-014-0550-8","volume":"15","author":"MI Love","year":"2014","unstructured":"Love MI, Huber W, Anders S (2014) Moderated estimation of fold change and dispersion for RNAseq data with DESeq2. Genome Biol 15:550. https:\/\/doi.org\/10.1186\/s13059-014-0550-8","journal-title":"Genome Biol"},{"key":"624_CR33","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1186\/1471-2164-15-219","volume":"17","author":"K Mishima","year":"2016","unstructured":"Mishima K, Fujiwara T, Iki T, Kuroda K, Yamashita K, Tamura M, Fujisawa Y, Watanabe A (2016) Transcriptome sequencing and profiling of expressed genes in cambial zone and differentiating xylem of Japanese cedar (Cryptomeria japonica). BMC Genomics 17:803. https:\/\/doi.org\/10.1186\/1471-2164-15-219","journal-title":"BMC Genomics"},{"key":"624_CR34","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s40104-016-0130-8","volume":"8","author":"JK Oh","year":"2017","unstructured":"Oh JK, Pajarillo E, Chae JP, Kim IH, Yang DS, Kang DK (2017) Effects of Bacillus subtilis CSL2 on the composition and functional diversity of the faecal microbiota of broiler chickens challenged with Salmonella gallinarum. J Anim Sci Biotechnol 8:1. https:\/\/doi.org\/10.1186\/s40104-016-0130-8","journal-title":"J Anim Sci Biotechnol"},{"key":"624_CR35","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1002\/mnfr.201300296","volume":"58","author":"M Ortega-Gonz\u00e1lez","year":"2014","unstructured":"Ortega-Gonz\u00e1lez M, Oc\u00f3n B, Romero-Calvo I, Anzola A, Guadix E, Zarzuelo A, Mart\u00ednez-Augustin O (2014) Nondigestible oligosaccharides exert nonprebiotic effects on intestinal epithelial cells enhancing the immune response via activation of TLR4-NF-\u03baB. Mol Nutr Food Res 58:384\u2013393. https:\/\/doi.org\/10.1002\/mnfr.201300296","journal-title":"Mol Nutr Food Res"},{"key":"624_CR36","doi-asserted-by":"publisher","first-page":"699","DOI":"10.3920\/BM2016.0080","volume":"7","author":"CM Pender","year":"2016","unstructured":"Pender CM, Kim S, Potter TD, Ritzi MM, Young M, Dalloul RA (2016) Effects of in ovo supplementation of probiotics on performance and immunocompetence of broiler chicks to an Eimeria challenge. Benef Microbes 7:699\u2013705. https:\/\/doi.org\/10.3920\/BM2016.0080","journal-title":"Benef Microbes"},{"key":"624_CR37","doi-asserted-by":"publisher","first-page":"1052","DOI":"10.3382\/ps\/pew381","volume":"96","author":"CM Pender","year":"2017","unstructured":"Pender CM, Kim S, Potter TD, Ritzi MM, Young M, Dalloul RA (2017) In ovo supplementation of probiotics and its effects on performance and immune-related gene expression in broiler chicks. Poult Sci 96:1052\u20131062. https:\/\/doi.org\/10.3382\/ps\/pew381","journal-title":"Poult Sci"},{"key":"624_CR38","doi-asserted-by":"publisher","first-page":"1650","DOI":"10.1038\/nprot.2016.095","volume":"11","author":"M Pertea","year":"2016","unstructured":"Pertea M, Kim D, Pertea GM, Leek JT, Salzberg SL (2016) Transcript-level expression analysis of RNA-seq experiments with HISAT, StringTie and Ballgown. Nat Protoc 11:1650. https:\/\/doi.org\/10.1038\/nprot.2016.095","journal-title":"Nat Protoc"},{"key":"624_CR39","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1038\/nbt.3122","volume":"33","author":"M Pertea","year":"2015","unstructured":"Pertea M, Pertea GM, Antonescu CM, Chang TC, Mendell JT, Salzberg SL (2015) String Tie enables improved reconstruction of a transcriptome from RNA-seq reads. Nat Biotechnol 33:290. https:\/\/doi.org\/10.1038\/nbt.3122","journal-title":"Nat Biotechnol"},{"key":"624_CR40","doi-asserted-by":"publisher","first-page":"673","DOI":"10.2527\/jas.2006-535","volume":"85","author":"S Pi\u00e9","year":"2007","unstructured":"Pi\u00e9 S, Awati A, Vida S, Falluel I, Williams BA, Oswald IP (2007) Effects of added fermentable carbohydrates in the diet on intestinal proinflammatory cytokine-specific mRNA content in weaning piglets 1. J Anim Sci 85:673\u2013683. https:\/\/doi.org\/10.2527\/jas.2006-535","journal-title":"J Anim Sci"},{"key":"624_CR41","doi-asserted-by":"publisher","first-page":"276","DOI":"10.3382\/ps.2009-00336","volume":"89","author":"A Rebole","year":"2010","unstructured":"Rebole A, Ortiz LT, Rodriguez ML, Alzueta C, Trevino J, Velasco S (2010) Effects of inulin and enzyme complex, individually or in combination, on growth performance, intestinal microflora, cecal fermentation characteristics, and jejunal histomorphology in broiler chickens fed a wheat- and barley-based diet. Poultry Sci 89:276\u2013286. https:\/\/doi.org\/10.3382\/ps.2009-00336","journal-title":"Poultry Sci"},{"key":"624_CR42","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1093\/bioinformatics\/btp616","volume":"26","author":"MD Robinson","year":"2010","unstructured":"Robinson MD, McCarthy DJ, Smyth GK (2010) edgeR: a Bioconductor package for differential expression analysis of digital gene expression data. Bioinformatics 26:139\u2013140. https:\/\/doi.org\/10.1093\/bioinformatics\/btp616","journal-title":"Bioinformatics"},{"key":"624_CR43","doi-asserted-by":"publisher","first-page":"1103","DOI":"10.1186\/1297-9716-44-1","volume":"41","author":"S Saeed","year":"2013","unstructured":"Saeed S, Mohammad RS, Hasan H (2013) Effects of probiotic yoghurt and prebiotic utilization on performance and some haematological parameters in broiler chickens. Acta Scientiae Veterinari 41:1103. https:\/\/doi.org\/10.1186\/1297-9716-44-1","journal-title":"Acta Scientiae Veterinari"},{"key":"624_CR44","doi-asserted-by":"publisher","unstructured":"Sanchez B, Delgado S, Blanco-Miguez A, Lourenco A, Gueimonde M, Margolles A (2017) Probiotics, gut microbiota, and their influence on host health and disease. Mol Nutr Food Res 61(1). https:\/\/doi.org\/10.1002\/mnfr.201600240","DOI":"10.1002\/mnfr.201600240"},{"key":"624_CR45","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1080\/10408398.2014.887055","volume":"57","author":"LK Sarao","year":"2017","unstructured":"Sarao LK, Arora M (2017) Probiotics, prebiotics, and microencapsulation: a review. Crit Rev Food Sci Nutr 57:344\u2013371. https:\/\/doi.org\/10.1080\/10408398.2014.887055","journal-title":"Crit Rev Food Sci Nutr"},{"key":"624_CR46","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1080\/09712119.2013.825619","volume":"42","author":"R Tohidi","year":"2014","unstructured":"Tohidi R, Idris IB, Panandam JM, Hair-Bejo M (2014) Early immune gene expression responses to Salmonella enteritidis infection in indigenous chickens. J Appl Anim Res 42:204\u2013207. https:\/\/doi.org\/10.1080\/09712119.2013.825619","journal-title":"J Appl Anim Res"},{"key":"624_CR47","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1111\/jpn.12666","volume":"102","author":"THT Tran","year":"2018","unstructured":"Tran THT, Everaert N, Bindelle J (2018) Review on the effects of potential prebiotics on controlling intestinal enteropathogens Salmonella and Escherichia coli in pig production. J Anim Physiol Anim Nutr 102:17\u201332. https:\/\/doi.org\/10.1111\/jpn.12666","journal-title":"J Anim Physiol Anim Nutr"},{"key":"624_CR48","doi-asserted-by":"publisher","first-page":"e362","DOI":"10.1111\/jpn.12613","volume":"101","author":"PG Vineetha","year":"2017","unstructured":"Vineetha PG, Tomar S, Saxena VK, Kapgate M, Suvarna A, Adil K (2017) Effect of laboratory-isolated Lactobacillus plantarum LGFCP4 from gastrointestinal tract of guinea fowl on growth performance, carcass traits, intestinal histomorphometry and gastrointestinal microflora population in broiler chicken. J Anim Physiol Anim Nutr 101:e362\u2013e370. https:\/\/doi.org\/10.1111\/jpn.12613","journal-title":"J Anim Physiol Anim Nutr"},{"key":"624_CR49","doi-asserted-by":"publisher","first-page":"414","DOI":"10.1080\/10408398.2012.656772","volume":"55","author":"L Vogt","year":"2015","unstructured":"Vogt L, Meyer D, Pullens G, Faas M, Smelt M, Venema K, Ramasamy U, Schols A, De Vos P (2015) Immunological properties of inulin-type fructans. Crit Rev Food Sci Nutr 55:414\u2013436. https:\/\/doi.org\/10.1080\/10408398.2012.656772","journal-title":"Crit Rev Food Sci Nutr"},{"key":"624_CR50","doi-asserted-by":"publisher","first-page":"482","DOI":"10.3389\/fimmu.2014.00482","volume":"5","author":"HP Wigley","year":"2014","unstructured":"Wigley HP (2014) Salmonella enterica in the chicken: how it has helped our understanding of immunology in a non-biomedical model species. Front Immunol 5:482. https:\/\/doi.org\/10.3389\/fimmu.2014.00482","journal-title":"Front Immunol"},{"key":"624_CR51","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1079\/BJNBJN\/2002529","volume":"77","author":"Q Xu","year":"2009","unstructured":"Xu Q, Chao YL, Wan QB (2009) Health benefit application of functional oligosaccharides. Carbohydrate Polymers 77:435\u2013441. https:\/\/doi.org\/10.1079\/BJNBJN\/2002529","journal-title":"Carbohydrate Polymers"},{"key":"624_CR52","doi-asserted-by":"publisher","first-page":"971","DOI":"10.3945\/jn.110.136176","volume":"141","author":"M Zenhom","year":"2011","unstructured":"Zenhom M, Hyder A, de Vrese M, Heller KJ, Roeder T, Schrezenmeir J (2011) Prebiotic oligosaccharides reduce proinflammatory cytokines in intestinal Caco-2 cells via activation of PPAR\u03b3 and peptidoglycan recognition protein 3\u20133. J Nutr 141:971\u2013977. https:\/\/doi.org\/10.3945\/jn.110.136176","journal-title":"J Nutr"},{"key":"624_CR53","doi-asserted-by":"publisher","first-page":"1274","DOI":"10.1360\/aps040178","volume":"45","author":"Y Zhang","year":"2006","unstructured":"Zhang Y, Xiao LH, Chen X, Sun J, Zhang MZ, Luo WX, Tian QP, Wang FF, Wei J, Guo RH, Jian CS (2006) Analysis of genetic diversity and relationship among local chicken breeds in Guizhou by using microsatellites marker. Xvmu Shouyi Xuebao (Acta Veterinariaet, Zootechnica Sinica) 45:1274\u20131281. https:\/\/doi.org\/10.1360\/aps040178","journal-title":"Xvmu Shouyi Xuebao (Acta Veterinariaet, Zootechnica Sinica)"},{"key":"624_CR54","doi-asserted-by":"publisher","first-page":"198","DOI":"10.1038\/s41586-018-0372-z","volume":"560","author":"Z Zhong","year":"2018","unstructured":"Zhong Z, Liang S, Sanchezlopez E, He F, Shalapour S, Lin X, Wong J, Ding S, Seki E, Schnabl B (2018) New mitochondrial DNA synthesis enables NLRP3 inflammasome activation. Nature 560:198\u2013203. https:\/\/doi.org\/10.1038\/s41586-018-0372-z","journal-title":"Nature"},{"key":"624_CR55","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1016\/j.immuni.2012.05.008","volume":"36","author":"A Zlotnik","year":"2012","unstructured":"Zlotnik A, Yoshie O (2012) The chemokine superfamily revisited. Immunity 36:705\u2013716. https:\/\/doi.org\/10.1016\/j.immuni.2012.05.008","journal-title":"Immunity"}],"container-title":["Journal of Applied Genetics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s13353-021-00624-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s13353-021-00624-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s13353-021-00624-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,8]],"date-time":"2021-04-08T13:39:12Z","timestamp":1617889152000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s13353-021-00624-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,27]]},"references-count":55,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,5]]}},"alternative-id":["624"],"URL":"https:\/\/doi.org\/10.1007\/s13353-021-00624-5","relation":{},"ISSN":["1234-1983","2190-3883"],"issn-type":[{"value":"1234-1983","type":"print"},{"value":"2190-3883","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2,27]]},"assertion":[{"value":"3 November 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 February 2021","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 February 2021","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 February 2021","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All the methods used in this study were carried out according to the guiding principles of the Chinese Legislation on the Use and Care of Laboratory Animals. Protocol was approved by the Institutional Ethic Committee of Tianshui normal university (TSNU).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}