{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T22:58:00Z","timestamp":1792796280282,"version":"4.5.0"},"reference-count":36,"publisher":"American Chemical Society (ACS)","issue":"12","license":[{"start":{"date-parts":[[2015,10,19]],"date-time":"2015-10-19T00:00:00Z","timestamp":1445212800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J. Am. Soc. Mass Spectrom."],"published-print":{"date-parts":[[2015,12,1]]},"DOI":"10.1007\/s13361-015-1251-6","type":"journal-article","created":{"date-parts":[[2015,10,20]],"date-time":"2015-10-20T03:57:33Z","timestamp":1445313453000},"page":"1970-1980","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Neuropeptidomics Mass Spectrometry Reveals Signaling Networks Generated by Distinct Protease Pathways in Human Systems"],"prefix":"10.1021","volume":"26","author":[{"given":"Vivian","family":"Hook","sequence":"first","affiliation":[{"name":"Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 92093-0719, La Jolla, CA, USA"},{"name":"School of Medicine, Department of Neurosciences and Department of Pharmacology, University of California, San Diego, 92093-0719, La Jolla, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuno","family":"Bandeira","sequence":"additional","affiliation":[{"name":"Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 92093-0719, La Jolla, CA, USA"},{"name":"Department of Computer Science and Engineering, University of California, San Diego, 92093-0719, La Jolla, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2015,10,19]]},"reference":[{"key":"CR1\/citCR1","volume-title":"Brain Peptides","author":"Krieger D","year":"1983"},{"key":"CR2\/citCR2","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1152\/physrev.1991.71.4.1017","volume":"71","author":"Strand FL","year":"1991","journal-title":"Physiol. Rev."},{"key":"CR3\/citCR3","unstructured":"Siegel, GJ; Albers, RW; Fisher, SK; Uhler, MD Basic Neurochemistry1999PhiladelphiaLippincott Williams and Wilkins363382"},{"key":"CR4\/citCR4","volume-title":"Handbook of biologically active peptides","author":"Kastin AJ","year":"2006"},{"key":"CR5\/citCR5","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.pharmtox.48.113006.094812"},{"key":"CR6\/citCR6","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.ne.07.030184.001255"},{"key":"CR7\/citCR7","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2013.08.028"},{"key":"CR8\/citCR8","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291X(69)90868-7"},{"key":"CR9\/citCR9","first-page":"1870","volume":"269","author":"Burgus R","year":"1969","journal-title":"C.R. Acad Sci Hebd. Seances Acad. Sci. Ser. D."},{"key":"CR10\/citCR10","doi-asserted-by":"publisher","DOI":"10.1172\/JCI104130"},{"key":"CR11\/citCR11","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btr445"},{"key":"CR12\/citCR12","doi-asserted-by":"publisher","DOI":"10.1021\/pr100358b"},{"key":"CR13\/citCR13","doi-asserted-by":"publisher","DOI":"10.1016\/1044-0305(94)80016-2"},{"key":"CR14\/citCR14","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1522-2683(19991201)20:18<3551::AID-ELPS3551>3.0.CO;2-2"},{"key":"CR15\/citCR15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jprot.2010.08.009"},{"key":"CR16\/citCR16","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.M000136-MCP201"},{"key":"CR17\/citCR17","doi-asserted-by":"crossref","unstructured":"Burbach, J.P.H.: Neuropeptides from concept to online database www.neuropeptides.nl. Eur. J. Pharmacol. 626, 27\u201348 (2010)","DOI":"10.1016\/j.ejphar.2009.10.015"},{"key":"CR18\/citCR18","doi-asserted-by":"crossref","unstructured":"Wang, Y., Wang, M., Yin, S., Jang, R., Wang, J., Xue, Z., Xu, T.: NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). bav038 (2015)","DOI":"10.1093\/database\/bav038"},{"key":"CR19\/citCR19","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0111112"},{"key":"CR20\/citCR20","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M111.310607"},{"key":"CR21\/citCR21","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.R113.481549"},{"key":"CR22\/citCR22","doi-asserted-by":"publisher","DOI":"10.1016\/j.npep.2010.08.003"},{"key":"CR23\/citCR23","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2006.04067.x"},{"key":"CR24\/citCR24","doi-asserted-by":"publisher","DOI":"10.1021\/bi047852m"},{"key":"CR25\/citCR25","doi-asserted-by":"publisher","DOI":"10.1038\/nrd3699"},{"key":"CR26\/citCR26","doi-asserted-by":"publisher","DOI":"10.1016\/S1367-5931(98)80033-1"},{"key":"CR27\/citCR27","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-61779-204-5_1"},{"key":"CR28\/citCR28","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1531542100"},{"key":"CR29\/citCR29","doi-asserted-by":"publisher","DOI":"10.1021\/bi982175f"},{"key":"CR30\/citCR30","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/20.17.4629"},{"key":"CR31\/citCR31","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0041134"},{"key":"CR32\/citCR32","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2007.324"},{"key":"CR33\/citCR33","doi-asserted-by":"publisher","DOI":"10.1016\/j.stemcr.2014.08.001"},{"key":"CR34\/citCR34","doi-asserted-by":"publisher","DOI":"10.1038\/nrm3448"},{"key":"CR35\/citCR35","doi-asserted-by":"publisher","DOI":"10.1517\/17460441.2015.1037737"},{"key":"CR36\/citCR36","doi-asserted-by":"publisher","DOI":"10.1016\/j.ab.2009.07.021"}],"container-title":["Journal of the American Society for Mass Spectrometry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s13361-015-1251-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s13361-015-1251-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1007\/s13361-015-1251-6","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,22]],"date-time":"2021-08-22T20:25:13Z","timestamp":1629663913000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1007\/s13361-015-1251-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10,19]]},"references-count":36,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2015,12,1]]}},"alternative-id":["10.1007\/s13361-015-1251-6"],"URL":"https:\/\/doi.org\/10.1007\/s13361-015-1251-6","relation":{},"ISSN":["1044-0305"],"issn-type":[{"value":"1044-0305","type":"print"}],"subject":[],"published":{"date-parts":[[2015,10,19]]}}}