{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T04:12:27Z","timestamp":1790741547447,"version":"4.1.0"},"reference-count":66,"publisher":"American Chemical Society (ACS)","issue":"6","license":[{"start":{"date-parts":[[2016,2,19]],"date-time":"2016-02-19T00:00:00Z","timestamp":1455840000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"crossref","award":["078114"],"award-info":[{"award-number":["078114"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J. Am. Soc. Mass Spectrom."],"published-print":{"date-parts":[[2016,6,1]]},"DOI":"10.1007\/s13361-016-1347-7","type":"journal-article","created":{"date-parts":[[2016,2,19]],"date-time":"2016-02-19T14:56:34Z","timestamp":1455893794000},"page":"1010-1018","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["Human Islet Amyloid Polypeptide N-Terminus Fragment Self-Assembly: Effect of Conserved Disulfide Bond on Aggregation Propensity"],"prefix":"10.1021","volume":"27","author":[{"given":"Alexandre I.","family":"Ilitchev","sequence":"first","affiliation":[{"name":"Department of Chemistry and Biochemistry, University of California, 93106, Santa Barbara, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maxwell J.","family":"Giammona","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, University of California, 93106, Santa Barbara, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thanh D.","family":"Do","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, University of California, 93106, Santa Barbara, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy G.","family":"Wong","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Stony Brook University, 11794-3400, Stony Brook, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven K.","family":"Buratto","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, University of California, 93106, Santa Barbara, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joan-Emma","family":"Shea","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, University of California, 93106, Santa Barbara, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel P.","family":"Raleigh","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Stony Brook University, 11794-3400, Stony Brook, NY, USA"},{"name":"Research Department of Structural and Molecular Biology, University College London, Gower Street, WC1E 6BT, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael T.","family":"Bowers","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, University of California, 93106, Santa Barbara, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2016,2,19]]},"reference":[{"key":"CR1\/citCR1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00042.2009"},{"key":"CR2\/citCR2","doi-asserted-by":"publisher","DOI":"10.2337\/db06-1579"},{"key":"CR3\/citCR3","doi-asserted-by":"publisher","DOI":"10.1210\/er.2007-0037"},{"key":"CR4\/citCR4","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-006-0590-z"},{"key":"CR5\/citCR5","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2004-0405"},{"key":"CR6\/citCR6","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.84.11.3881"},{"key":"CR7\/citCR7","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.84.23.8628"},{"key":"CR8\/citCR8","doi-asserted-by":"publisher","DOI":"10.1016\/j.sbi.2012.11.003"},{"key":"CR9\/citCR9","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-291X(05)81133-7"},{"key":"CR10\/citCR10","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.1999.2646"},{"key":"CR11\/citCR11","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00703.2009"},{"key":"CR12\/citCR12","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc0802893"},{"key":"CR13\/citCR13","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0909024107"},{"key":"CR14\/citCR14","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2004.08.004"},{"key":"CR15\/citCR15","doi-asserted-by":"publisher","DOI":"10.1021\/bi034889i"},{"key":"CR16\/citCR16","doi-asserted-by":"publisher","DOI":"10.1126\/science.1079469"},{"key":"CR17\/citCR17","doi-asserted-by":"publisher","DOI":"10.1038\/nchem.945"},{"key":"CR18\/citCR18","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2014.05.015"},{"key":"CR19\/citCR19","doi-asserted-by":"publisher","DOI":"10.1038\/nchembio.635"},{"key":"CR20\/citCR20","doi-asserted-by":"publisher","DOI":"10.1021\/ja406831n"},{"key":"CR21\/citCR21","doi-asserted-by":"publisher","DOI":"10.1038\/nchem.2129"},{"key":"CR22\/citCR22","doi-asserted-by":"publisher","DOI":"10.1021\/ja903814q"},{"key":"CR23\/citCR23","doi-asserted-by":"publisher","DOI":"10.1021\/ja1081537"},{"key":"CR24\/citCR24","doi-asserted-by":"publisher","DOI":"10.1021\/ja504031d"},{"key":"CR25\/citCR25","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.1999.3286"},{"key":"CR26\/citCR26","doi-asserted-by":"publisher","DOI":"10.1021\/bi048812l"},{"key":"CR27\/citCR27","doi-asserted-by":"crossref","unstructured":"Gilead, S., and Gazit, E.: The role of the 14-20 domain of the islet amyloid polypeptide in amyloid formation. Exp Diabetes Res.\u00a02008,\u00a0256954 (2008)","DOI":"10.1155\/2008\/256954"},{"key":"CR28\/citCR28","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2836(02)00164-X"},{"key":"CR29\/citCR29","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.2001.5244"},{"key":"CR30\/citCR30","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpc.2010.01.006"},{"key":"CR31\/citCR31","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1314481110"},{"key":"CR32\/citCR32","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.87.13.5036"},{"key":"CR33\/citCR33","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.1999.3422"},{"key":"CR34\/citCR34","doi-asserted-by":"publisher","DOI":"10.1016\/S1047-8477(02)00630-5"},{"key":"CR35\/citCR35","doi-asserted-by":"publisher","DOI":"10.2174\/0929867023369187"},{"key":"CR36\/citCR36","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.86.24.9662"},{"key":"CR37\/citCR37","doi-asserted-by":"crossref","first-page":"E827","DOI":"10.1152\/ajpendo.1998.274.5.E827","volume":"274","author":"Cornish J","year":"1998","journal-title":"Am J Physiol-Endocrinol Metab"},{"key":"CR38\/citCR38","doi-asserted-by":"publisher","DOI":"10.1124\/mol.104.008615"},{"key":"CR39\/citCR39","doi-asserted-by":"publisher","DOI":"10.2337\/diab.42.2.330"},{"key":"CR40\/citCR40","doi-asserted-by":"publisher","DOI":"10.1006\/jsbi.2000.4268"},{"key":"CR41\/citCR41","doi-asserted-by":"publisher","DOI":"10.1110\/ps.041051205"},{"key":"CR42\/citCR42","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M406853200"},{"key":"CR43\/citCR43","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpj.2013.08.026"},{"key":"CR44\/citCR44","doi-asserted-by":"publisher","DOI":"10.1038\/nchem.1889"},{"key":"CR45\/citCR45","doi-asserted-by":"publisher","DOI":"10.1039\/C0AN00373E"},{"key":"CR46\/citCR46","doi-asserted-by":"publisher","DOI":"10.1016\/j.cocis.2012.08.001"},{"key":"CR47\/citCR47","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0604035103"},{"key":"CR48\/citCR48","doi-asserted-by":"publisher","DOI":"10.1038\/nnano.2010.59"},{"key":"CR49\/citCR49","doi-asserted-by":"publisher","DOI":"10.1038\/nsmb.1799"},{"key":"CR50\/citCR50","doi-asserted-by":"publisher","DOI":"10.1021\/ol101981b"},{"key":"CR51\/citCR51","doi-asserted-by":"publisher","DOI":"10.1021\/ol047480+"},{"key":"CR52\/citCR52","doi-asserted-by":"publisher","DOI":"10.1016\/S1387-3806(01)00517-6"},{"key":"CR53\/citCR53","doi-asserted-by":"crossref","DOI":"10.1002\/3527602852","volume-title":"Transport properties of ions in gases","author":"Mason EA","year":"1988"},{"key":"CR54\/citCR54","doi-asserted-by":"publisher","DOI":"10.1021\/ja00214a001"},{"key":"CR55\/citCR55","doi-asserted-by":"publisher","DOI":"10.1021\/ct700301q"},{"key":"CR56\/citCR56","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.20291"},{"key":"CR57\/citCR57","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-987X(199709)18:12<1463::AID-JCC4>3.0.CO;2-H"},{"key":"CR58\/citCR58","doi-asserted-by":"crossref","unstructured":"Miyamoto, S., Kollman, P.A.: SETTLE: an analytical version of the shake and rattle algorithm for rigid water models. J Comput Chem 13(952\u2013962) (2004)","DOI":"10.1002\/jcc.540130805"},{"key":"CR59\/citCR59","doi-asserted-by":"publisher","DOI":"10.1063\/1.464397"},{"key":"CR60\/citCR60","doi-asserted-by":"publisher","DOI":"10.1063\/1.449071"},{"key":"CR61\/citCR61","doi-asserted-by":"publisher","DOI":"10.1039\/b716554d"},{"key":"CR62\/citCR62","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1521-3773(19990115)38:1\/2<236::AID-ANIE236>3.0.CO;2-M"},{"key":"CR63\/citCR63","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijms.2011.06.014"},{"key":"CR64\/citCR64","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijms.2012.08.027"},{"key":"CR65\/citCR65","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M312452200"},{"key":"CR66\/citCR66","doi-asserted-by":"publisher","DOI":"10.1021\/bi101908m"}],"container-title":["Journal of the American Society for Mass Spectrometry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s13361-016-1347-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s13361-016-1347-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1007\/s13361-016-1347-7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,27]],"date-time":"2021-08-27T01:08:14Z","timestamp":1630026494000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1007\/s13361-016-1347-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2,19]]},"references-count":66,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2016,6,1]]}},"alternative-id":["10.1007\/s13361-016-1347-7"],"URL":"https:\/\/doi.org\/10.1007\/s13361-016-1347-7","relation":{},"ISSN":["1044-0305"],"issn-type":[{"value":"1044-0305","type":"print"}],"subject":[],"published":{"date-parts":[[2016,2,19]]}}}