{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T12:18:26Z","timestamp":1779193106863,"version":"3.51.4"},"reference-count":40,"publisher":"Springer Science and Business Media LLC","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Neurovirol."],"published-print":{"date-parts":[[2012,4]]},"DOI":"10.1007\/s13365-012-0083-4","type":"journal-article","created":{"date-parts":[[2012,3,7]],"date-time":"2012-03-07T14:54:19Z","timestamp":1331132059000},"page":"91-99","source":"Crossref","is-referenced-by-count":15,"title":["Simian varicella virus infection of Chinese rhesus macaques produces ganglionic infection in the absence of rash"],"prefix":"10.1007","volume":"18","author":[{"given":"Werner J. D.","family":"Ouwendijk","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ravi","family":"Mahalingam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vicki","family":"Traina-Dorge","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Geert","family":"van Amerongen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary","family":"Wellish","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Albert D. M. E.","family":"Osterhaus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Don","family":"Gilden","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georges M. G. M.","family":"Verjans","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2012,3,8]]},"reference":[{"key":"83_CR1","doi-asserted-by":"crossref","first-page":"2005","DOI":"10.1128\/JVI.74.4.2005-2010.2000","volume":"74","author":"PW Annunziato","year":"2000","unstructured":"Annunziato PW, Lungu O, Panagiotidis C, Zhang JH, Silvers DN, Gershon AA, Silverstein SJ (2000) Varicella-zoster virus proteins in skin lesions: implications for a novel role of ORF29p in chickenpox. J Virol 74:2005\u20132010","journal-title":"J Virol"},{"key":"83_CR2","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0022-3476(85)80468-6","volume":"106","author":"Y Asano","year":"1985","unstructured":"Asano Y, Itakura N, Hiroishi Y, Hirose S, Nagai T, Ozaki T, Yazaki T, Yamanishi K, Takahashi M (1985) Viremia is present in incubation period in nonimmunocompromised children with varicella. J Pediatr 106:69\u201371","journal-title":"J Pediatr"},{"key":"83_CR3","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/1743-422X-2-2","volume":"2","author":"AG Bruce","year":"2005","unstructured":"Bruce AG, Bakke AM, Thouless ME, Rose TM (2005) Development of a real-time QPCR assay for the detection of RV2 lineage-specific rhadinoviruses in macaques and baboons. Virol J 2:2","journal-title":"Virol J"},{"key":"83_CR4","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1126\/science.1139247","volume":"316","author":"RA Gibbs","year":"2007","unstructured":"Gibbs RA, Rogers J, Katze MG, Bumgarner R, Weinstock GM, Mardis ER, Remington KA, Strausberg RL, Venter JC, Wilson RK, Batzer MA, Bustamante CD, Eichler EE, Hahn MW, Hardison RC, Makova KD, Miller W, Milosavljevic A, Palermo RE, Siepel A, Sikela JM, Attaway T, Bell S, Bernard KE, Buhay CJ, Chandrabose MN, Dao M, Davis C, Delehaunty KD, Ding Y, Dinh HH, Dugan-Rocha S, Fulton LA, Gabisi RA, Garner TT, Godfrey J, Hawes AC, Hernandez J, Hines S, Holder M, Hume J, Jhangiani SN, Joshi V, Khan ZM, Kirkness EF, Cree A, Fowler RG, Lee S, Lewis LR, Li Z, Liu YS, Moore SM, Muzny D, Nazareth LV, Ngo DN, Okwuonu GO, Pai G, Parker D, Paul HA, Pfannkoch C, Pohl CS, Rogers YH, Ruiz SJ, Sabo A, Santibanez J, Schneider BW, Smith SM, Sodergren E, Svatek AF, Utterback TR, Vattathil S, Warren W, White CS, Chinwalla AT, Feng Y, Halpern AL, Hillier LW, Huang X, Minx P, Nelson JO, Pepin KH, Qin X, Sutton GG, Venter E, Walenz BP, Wallis JW, Worley KC, Yang SP, Jones SM, Marra MA, Rocchi M, Schein JE, Baertsch R, Clarke L, Csuros M, Glasscock J, Harris RA, Havlak P, Jackson AR, Jiang H et al (2007) Evolutionary and biomedical insights from the rhesus macaque genome. Science 316:222\u2013234","journal-title":"Science"},{"key":"83_CR5","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1056\/NEJM200003023420906","volume":"342","author":"DH Gilden","year":"2000","unstructured":"Gilden DH, Kleinschmidt-DeMasters BK, LaGuardia JJ, Mahalingam R, Cohrs RJ (2000) Neurologic complications of the reactivation of varicella-zoster virus. N Engl J Med 342:635\u2013645","journal-title":"N Engl J Med"},{"key":"83_CR6","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1006\/viro.2001.0912","volume":"284","author":"WL Gray","year":"2001","unstructured":"Gray WL, Starnes B, White MW, Mahalingam R (2001) The DNA sequence of the simian varicella virus genome. Virology 284:123\u2013130","journal-title":"Virology"},{"key":"83_CR7","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1111\/j.1600-0684.1998.tb00069.x","volume":"27","author":"WL Gray","year":"1998","unstructured":"Gray WL, Williams RJ, Chang R, Soike KF (1998) Experimental simian varicella virus infection of St Kitts vervet monkeys. J Med Primatol 27:177\u2013183","journal-title":"J Med Primatol"},{"key":"83_CR8","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1089\/vim.1996.9.241","volume":"9","author":"AR Hayward","year":"1996","unstructured":"Hayward AR, Buda K, Jones M, White CJ, Levin MJ (1996) Varicella zoster virus-specific cytotoxicity following secondary immunization with live or killed vaccine. Viral Immunol 9:241\u2013245","journal-title":"Viral Immunol"},{"key":"83_CR9","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1016\/S0140-6736(06)69561-5","volume":"368","author":"U Heininger","year":"2006","unstructured":"Heininger U, Seward JF (2006) Varicella. Lancet 368:1365\u20131376","journal-title":"Lancet"},{"key":"83_CR10","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1126\/science.1140462","volume":"316","author":"RD Hernandez","year":"2007","unstructured":"Hernandez RD, Hubisz MJ, Wheeler DA, Smith DG, Ferguson B, Rogers J, Nazareth L, Indap A, Bourquin T, McPherson J, Muzny D, Gibbs R, Nielsen R, Bustamante CD (2007) Demographic histories and patterns of linkage disequilibrium in Chinese and Indian rhesus macaques. Science 316:240\u2013243","journal-title":"Science"},{"key":"83_CR11","first-page":"9","volume":"58","author":"RE Hope-Simpson","year":"1965","unstructured":"Hope-Simpson RE (1965) The nature of Herpes Zoster: a long-term study and a new hypothesis. Proc R Soc Med 58:9\u201320","journal-title":"Proc R Soc Med"},{"key":"83_CR12","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1007\/BF03210846","volume":"16","author":"PG Kennedy","year":"2010","unstructured":"Kennedy PG, Cohrs RJ (2010) Varicella-zoster virus human ganglionic latency: a current summary. J Neurovirol 16:411\u2013418","journal-title":"J Neurovirol"},{"key":"83_CR13","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1023\/B:VIRU.0000025774.19557.39","volume":"28","author":"PG Kennedy","year":"2004","unstructured":"Kennedy PG, Grinfeld E, Traina-Dorge V, Gilden DH, Mahalingam R (2004) Neuronal localization of simian varicella virus DNA in ganglia of naturally infected African green monkeys. Virus Genes 28:273\u2013276","journal-title":"Virus Genes"},{"key":"83_CR14","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1093\/infdis\/170.3.522","volume":"170","author":"MJ Levin","year":"1994","unstructured":"Levin MJ, Murray M, Zerbe GO, White CJ, Hayward AR (1994) Immune responses of elderly persons 4\u00a0years after receiving a live attenuated varicella vaccine. J Infect Dis 170:522\u2013526","journal-title":"J Infect Dis"},{"key":"83_CR15","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1097\/00002030-200207260-00005","volume":"16","author":"B Ling","year":"2002","unstructured":"Ling B, Veazey RS, Luckay A, Penedo C, Xu K, Lifson JD, Marx PA (2002) SIV(mac) pathogenesis in rhesus macaques of Chinese and Indian origin compared with primary HIV infections in humans. AIDS 16:1489\u20131496","journal-title":"AIDS"},{"key":"83_CR16","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/0042-6822(92)90749-F","volume":"188","author":"R Mahalingam","year":"1992","unstructured":"Mahalingam R, Clarke P, Wellish M, Dueland AN, Soike KF, Gilden DH, Cohrs R (1992) Prevalence and distribution of latent simian varicella virus DNA in monkey ganglia. Virology 188:193\u2013197","journal-title":"Virology"},{"key":"83_CR17","doi-asserted-by":"crossref","first-page":"2750","DOI":"10.1073\/pnas.88.7.2750","volume":"88","author":"R Mahalingam","year":"1991","unstructured":"Mahalingam R, Smith D, Wellish M, Wolf W, Dueland AN, Cohrs R, Soike K, Gilden D (1991) Simian varicella virus DNA in dorsal root ganglia. Proc Natl Acad Sci USA 88:2750\u20132752","journal-title":"Proc Natl Acad Sci USA"},{"key":"83_CR18","doi-asserted-by":"crossref","first-page":"12454","DOI":"10.1128\/JVI.01792-10","volume":"84","author":"R Mahalingam","year":"2010","unstructured":"Mahalingam R, Traina-Dorge V, Wellish M, Deharo E, Golive A, Messaoudi I, Gilden D (2010) Effect of time delay after necropsy on analysis of simian varicella-zoster virus expression in latently infected ganglia of rhesus macaques. J Virol 84:12454\u201312457","journal-title":"J Virol"},{"key":"83_CR19","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.virol.2007.06.025","volume":"368","author":"R Mahalingam","year":"2007","unstructured":"Mahalingam R, Traina-Dorge V, Wellish M, Lorino R, Sanford R, Ribka EP, Alleman SJ, Brazeau E, Gilden DH (2007) Simian varicella virus reactivation in cynomolgus monkeys. Virology 368:50\u201359","journal-title":"Virology"},{"key":"83_CR20","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1006\/viro.2000.0700","volume":"279","author":"R Mahalingam","year":"2001","unstructured":"Mahalingam R, Wellish M, Soike K, White T, Kleinschmidt-DeMasters BK, Gilden DH (2001) Simian varicella virus infects ganglia before rash in experimentally infected monkeys. Virology 279:339\u2013342","journal-title":"Virology"},{"key":"83_CR21","doi-asserted-by":"crossref","first-page":"438","DOI":"10.3109\/13550289809114543","volume":"4","author":"R Mahalingam","year":"1998","unstructured":"Mahalingam R, Wellish M, White T, Soike K, Cohrs R, Kleinschmidt-DeMasters BK, Gilden DH (1998) Infectious simian varicella virus expressing the green fluorescent protein. J Neurovirol 4:438\u2013444","journal-title":"J Neurovirol"},{"key":"83_CR22","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1086\/511274","volume":"195","author":"GN Malavige","year":"2007","unstructured":"Malavige GN, Jones L, Black AP, Ogg GS (2007) Rapid effector function of varicella-zoster virus glycoprotein I-specific CD4+ T cells many decades after primary infection. J Infect Dis 195:660\u2013664","journal-title":"J Infect Dis"},{"key":"83_CR23","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1111\/j.1365-2249.2008.03633.x","volume":"152","author":"GN Malavige","year":"2008a","unstructured":"Malavige GN, Jones L, Black AP, Ogg GS (2008a) Varicella zoster virus glycoprotein E-specific CD4+ T cells show evidence of recent activation and effector differentiation, consistent with frequent exposure to replicative cycle antigens in healthy immune donors. Clin Exp Immunol 152:522\u2013531","journal-title":"Clin Exp Immunol"},{"key":"83_CR24","doi-asserted-by":"crossref","first-page":"e3789","DOI":"10.1371\/journal.pone.0003789","volume":"3","author":"GN Malavige","year":"2008b","unstructured":"Malavige GN, Jones L, Kamaladasa SD, Wijewickrama A, Seneviratne SL, Black AP, Ogg GS (2008b) Viral load, clinical disease severity and cellular immune responses in primary varicella zoster virus infection in Sri Lanka. PLoS One 3:e3789","journal-title":"PLoS One"},{"key":"83_CR25","doi-asserted-by":"crossref","first-page":"6220","DOI":"10.1128\/JVI.02396-10","volume":"85","author":"A Markus","year":"2011","unstructured":"Markus A, Grigoryan S, Sloutskin A, Yee MB, Zhu H, Yang IH, Thakor NV, Sarid R, Kinchington PR, Goldstein RS (2011) Varicella-zoster virus (VZV) infection of neurons derived from human embryonic stem cells: direct demonstration of axonal infection, transport of VZV, and productive neuronal infection. J Virol 85:6220\u20136233","journal-title":"J Virol"},{"key":"83_CR26","doi-asserted-by":"crossref","first-page":"e1000657","DOI":"10.1371\/journal.ppat.1000657","volume":"5","author":"I Messaoudi","year":"2009","unstructured":"Messaoudi I, Barron A, Wellish M, Engelmann F, Legasse A, Planer S, Gilden D, Nikolich-Zugich J, Mahalingam R (2009) Simian varicella virus infection of rhesus macaques recapitulates essential features of varicella zoster virus infection in humans. PLoS Pathog 5:e1000657","journal-title":"PLoS Pathog"},{"key":"83_CR27","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1212\/WNL.30.6.582","volume":"30","author":"AE Miller","year":"1980","unstructured":"Miller AE (1980) Selective decline in cellular immune response to varicella-zoster in the elderly. Neurology 30:582\u2013587","journal-title":"Neurology"},{"key":"83_CR28","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1002\/jmv.1890440309","volume":"44","author":"T Ozaki","year":"1994","unstructured":"Ozaki T, Kajita Y, Asano Y, Aono T, Yamanishi K (1994) Detection of varicella-zoster virus DNA in blood of children with varicella. J Med Virol 44:263\u2013265","journal-title":"J Med Virol"},{"key":"83_CR29","doi-asserted-by":"crossref","first-page":"29","DOI":"10.4049\/jimmunol.168.1.29","volume":"168","author":"CJ Pitcher","year":"2002","unstructured":"Pitcher CJ, Hagen SI, Walker JM, Lum R, Mitchell BL, Maino VC, Axthelm MK, Picker LJ (2002) Development and homeostasis of T cell memory in rhesus macaque. J Immunol 168:29\u201343","journal-title":"J Immunol"},{"key":"83_CR30","doi-asserted-by":"crossref","first-page":"3971","DOI":"10.1128\/JVI.02592-07","volume":"82","author":"M Reichelt","year":"2008","unstructured":"Reichelt M, Zerboni L, Arvin AM (2008) Mechanisms of varicella-zoster virus neuropathogenesis in human dorsal root ganglia. J Virol 82:3971\u20133983","journal-title":"J Virol"},{"key":"83_CR31","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1002\/(SICI)1097-4652(200003)182:3<311::AID-JCP1>3.0.CO;2-9","volume":"182","author":"T Scholzen","year":"2000","unstructured":"Scholzen T, Gerdes J (2000) The Ki-67 protein: from the known and the unknown. J Cell Physiol 182:311\u2013322","journal-title":"J Cell Physiol"},{"key":"83_CR32","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/0166-3542(91)90055-V","volume":"16","author":"KF Soike","year":"1991","unstructured":"Soike KF, Huang JL, Zhang JY, Bohm R, Hitchcock MJ, Martin JC (1991) Evaluation of infrequent dosing regimens with (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]-cytosine (S-HPMPC) on simian varicella infection in monkeys. Antiviral Res 16:17\u201328","journal-title":"Antiviral Res"},{"key":"83_CR33","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.smim.2005.02.008","volume":"17","author":"B Srivastava","year":"2005","unstructured":"Srivastava B, Lindsley RC, Nikbakht N, Allman D (2005) Models for peripheral B cell development and homeostasis. Semin Immunol 17:175\u2013182","journal-title":"Semin Immunol"},{"key":"83_CR34","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.1016\/S0140-6736(74)90144-5","volume":"2","author":"M Takahashi","year":"1974","unstructured":"Takahashi M, Otsuka T, Okuno Y, Asano Y, Yazaki T (1974) Live vaccine used to prevent the spread of varicella in children in hospital. Lancet 2:1288\u20131290","journal-title":"Lancet"},{"key":"83_CR35","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1034\/j.1600-0684.2002.02003.x","volume":"31","author":"AM Trichel","year":"2002","unstructured":"Trichel AM, Rajakumar PA, Murphey-Corb M (2002) Species-specific variation in SIV disease progression between Chinese and Indian subspecies of rhesus macaque. J Med Primatol 31:171\u2013178","journal-title":"J Med Primatol"},{"key":"83_CR36","doi-asserted-by":"crossref","first-page":"3496","DOI":"10.1073\/pnas.0610847104","volume":"104","author":"GM Verjans","year":"2007","unstructured":"Verjans GM, Hintzen RQ, van Dun JM, Poot A, Milikan JC, Laman JD, Langerak AW, Kinchington PR, Osterhaus AD (2007) Selective retention of herpes simplex virus-specific T cells in latently infected human trigeminal ganglia. Proc Natl Acad Sci USA 104:3496\u20133501","journal-title":"Proc Natl Acad Sci USA"},{"key":"83_CR37","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1002\/cyto.a.20039","volume":"61","author":"Y Vugmeyster","year":"2004","unstructured":"Vugmeyster Y, Howell K, Bakshi A, Flores C, Hwang O, McKeever K (2004) B-cell subsets in blood and lymphoid organs in Macaca fascicularis. Cytometry A 61:69\u201375","journal-title":"Cytometry A"},{"issue":"Suppl 2","key":"83_CR38","doi-asserted-by":"crossref","first-page":"S143","DOI":"10.1086\/522130","volume":"197","author":"B Watson","year":"2008","unstructured":"Watson B (2008) Humoral and cell-mediated immune responses in children and adults after 1 and 2 doses of varicella vaccine. J Infect Dis 197(Suppl 2):S143\u2013S146","journal-title":"J Infect Dis"},{"key":"83_CR39","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1086\/651199","volume":"201","author":"A Weinberg","year":"2010","unstructured":"Weinberg A, Lazar AA, Zerbe GO, Hayward AR, Chan IS, Vessey R, Silber JL, MacGregor RR, Chan K, Gershon AA, Levin MJ (2010) Influence of age and nature of primary infection on varicella-zoster virus-specific cell-mediated immune responses. J Infect Dis 201:1024\u20131030","journal-title":"J Infect Dis"},{"key":"83_CR40","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1007\/82_2010_31","volume":"342","author":"A Weinberg","year":"2010","unstructured":"Weinberg A, Levin MJ (2010) VZV T cell-mediated immunity. Curr Top Microbiol Immunol 342:341\u2013357","journal-title":"Curr Top Microbiol Immunol"}],"container-title":["Journal of NeuroVirology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s13365-012-0083-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,20]],"date-time":"2017-06-20T11:19:22Z","timestamp":1497957562000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s13365-012-0083-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,3,8]]},"references-count":40,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,4]]}},"alternative-id":["83"],"URL":"https:\/\/doi.org\/10.1007\/s13365-012-0083-4","relation":{},"ISSN":["1355-0284","1538-2443"],"issn-type":[{"value":"1355-0284","type":"print"},{"value":"1538-2443","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,3,8]]}}}