{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T03:27:47Z","timestamp":1791343667957,"version":"4.3.1"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2012,12,12]],"date-time":"2012-12-12T00:00:00Z","timestamp":1355270400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2012,12,12]],"date-time":"2012-12-12T00:00:00Z","timestamp":1355270400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J. Neurovirol."],"published-print":{"date-parts":[[2013,2]]},"DOI":"10.1007\/s13365-012-0142-x","type":"journal-article","created":{"date-parts":[[2012,12,11]],"date-time":"2012-12-11T19:12:01Z","timestamp":1355253121000},"page":"75-81","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Varicella zoster virus infection of highly pure terminally differentiated human neurons"],"prefix":"10.1007","volume":"19","author":[{"given":"Xiaoli","family":"Yu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott","family":"Seitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiffany","family":"Pointon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacqueline L.","family":"Bowlin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Randall J.","family":"Cohrs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stipan","family":"Jonji\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00fcrgen","family":"Haas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"Wellish","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Don","family":"Gilden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2012,12,12]]},"reference":[{"key":"142_CR1","doi-asserted-by":"publisher","first-page":"10792","DOI":"10.1073\/pnas.0404016101","volume":"101","author":"A Baiker","year":"2004","unstructured":"Baiker A, Fabel K, Cozzio A, Zerboni L, Fabel K, Sommer M, Uchida N, He D, Weissman I, Arvin AM (2004) Varicella-zoster virus infection of human neural cells in vivo. Proc Natl Acad Sci USA 101:10792\u201310797. doi:10.1073\/pnas.0404016101","journal-title":"Proc Natl Acad Sci USA"},{"key":"142_CR2","doi-asserted-by":"publisher","first-page":"8436","DOI":"10.1128\/JVI.00515-11","volume":"85","author":"J Christensen","year":"2011","unstructured":"Christensen J, Steain M, Slobedman B, Abendroth A (2011) Differentiated neuroblastoma cells provide a highly efficient model for studies of productive varicella-zoster virus infection of neuronal cells. J Virol 85:8436\u20138442","journal-title":"J Virol"},{"key":"142_CR3","doi-asserted-by":"publisher","first-page":"7228","DOI":"10.1128\/JVI.76.14.7228-7238.2002","volume":"76","author":"RJ Cohrs","year":"2002","unstructured":"Cohrs RJ, Wischer J, Essman C, Gilden DH (2002) Characterization of varicella-zoster virus gene 21 and 29 proteins in infected cells. J Virol 76:7228\u20137238. doi:10.1128\/JVI.76.14.7228-7238.2002","journal-title":"J Virol"},{"key":"142_CR4","doi-asserted-by":"publisher","first-page":"3211","DOI":"10.1128\/JVI.06810-11","volume":"86","author":"A Dukhovny","year":"2012","unstructured":"Dukhovny A, Sloutskin A, Markus A, Yee MB, Kinchington PR, Goldstein RS (2012) Varicella-zoster virus infects human embryonic stem cell-derived neurons and neurospheres but not pluripotent embryonic stem cells or early progenitors. J Virol 86:3211\u20133218","journal-title":"J Virol"},{"key":"142_CR5","doi-asserted-by":"publisher","first-page":"12852","DOI":"10.1128\/JVI.77.23.12852-12864.2003","volume":"77","author":"C Hood","year":"2003","unstructured":"Hood C, Cunningham AL, Slobedman B, Boadle RA, Abendroth A (2003) Varicella-zoster virus-infected human sensory neurons are resistant to apoptosis, yet human foreskin fibroblasts are susceptible: evidence for a cell-type-specific apoptotic response. J Virol 77:12852\u201312864. doi:10.1128\/JVI.77.23.12852-12864","journal-title":"J Virol"},{"key":"142_CR6","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1089\/088282403322396073","volume":"16","author":"DH Gilden","year":"2003","unstructured":"Gilden DH, Cohrs RJ, Mahalingam R (2003) Clinical and molecular pathogenesis of varicella virus infection. Viral Immunol 16:243\u2013258","journal-title":"Viral Immunol"},{"key":"142_CR7","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1111\/j.1365-2990.2011.01167.x","volume":"37","author":"D Gilden","year":"2011","unstructured":"Gilden D, Mahalingam R, Nagel MA, Pugazhenthi S, Cohrs RJ (2011) Review: the neurobiology of varicella zoster virus infection. Neuropathol Appl Neurobiol 37:441\u2013463. doi:10.1111\/j.1365-2990.2011.01167","journal-title":"Neuropathol Appl Neurobiol"},{"key":"142_CR8","doi-asserted-by":"publisher","first-page":"6752","DOI":"10.1128\/JVI.02793-06","volume":"81","author":"K Gowrishankar","year":"2007","unstructured":"Gowrishankar K, Slobedman B, Cunningham AL, Miranda-Saksena M, Boadle RA, Abendroth A (2007) Productive varicella-zoster virus infection of cultured intact human ganglia. J Virol 81:6752\u20136756. doi:10.1128\/JVI.02793-06","journal-title":"J Virol"},{"key":"142_CR9","doi-asserted-by":"crossref","first-page":"2122","DOI":"10.1073\/pnas.93.5.2122","volume":"93","author":"R Mahalingam","year":"1996","unstructured":"Mahalingam R, Wellish M, Cohrs RJ, Debrus S, Piette J, Rentier B, Gilden DH (1996) Expression of protein encoded by varicella-zoster virus open reading frame 63 in latently infected human ganglionic neurons. Proc Natl Acad Sci USA 93:2122\u20132124","journal-title":"Proc Natl Acad Sci USA"},{"key":"142_CR10","doi-asserted-by":"publisher","first-page":"6220","DOI":"10.1128\/JVI.02396-10","volume":"85","author":"A Markus","year":"2011","unstructured":"Markus A, Grigoryan S, Sloutskin A, Yee MB, Zhu H, Yang IH, Thakor NV, Sarid R, Kinchington PR, Goldstein RS (2011) Varicella-zoster virus (VZV) infection of neurons derived from human embryonic stem cells: direct demonstration of axonal infection, transport of VZV, and productive neuronal infection. J Virol 85:6220\u20136233. doi:10.1128\/JVI.02396-10","journal-title":"J Virol"},{"key":"142_CR11","doi-asserted-by":"publisher","first-page":"1257","DOI":"10.1016\/S0140-6736(71)91777-6","volume":"1","author":"BL Padgett","year":"1971","unstructured":"Padgett BL, Walker DL, ZuRhein GM, Eckroade RJ, Dessel BH (1971) Cultivation of papova-like virus from human brain with progressive multifocal leucoencephalopathy. Lancet 1:1257\u20131260","journal-title":"Lancet"},{"key":"142_CR12","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1056\/NEJM196909112811103","volume":"281","author":"FE Payne","year":"1969","unstructured":"Payne FE, Baublis JV, Itabashi HH (1969) Isolation of measles virus from cell cultures of brain from a patient with subacute sclerosing panencephalitis. N Engl J Med 281:585\u2013589","journal-title":"N Engl J Med"},{"key":"142_CR13","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1002\/ana.410020313","volume":"2","author":"SA Plotkin","year":"1977","unstructured":"Plotkin SA, Stein S, Snyder M, Immesoete P (1977) Attempts to recover varicella virus from ganglia. Ann Neurol 2:249. doi:10.1002\/ana.410020313","journal-title":"Ann Neurol"},{"key":"142_CR14","doi-asserted-by":"publisher","first-page":"6678","DOI":"10.1128\/JVI.00445-11","volume":"85","author":"S Pugazhenthi","year":"2011","unstructured":"Pugazhenthi S, Nair S, Velmurugan K, Liang Q, Mahalingam R, Cohrs RJ, Nagel MA, Gilden D (2011) VZV infection of differentiated human neural stem cells. J Virol 85:6678\u20136686. doi:10.1128\/JVI.00445-11","journal-title":"J Virol"},{"key":"142_CR15","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1016\/0042-6822(86)90141-8","volume":"152","author":"B Wigdahl","year":"1986","unstructured":"Wigdahl B, Rong BL, Kinney-Thomas E (1986) Varicella-zoster virus infection of human sensory neurons. Virology 152:384\u2013399","journal-title":"Virology"},{"key":"142_CR16","doi-asserted-by":"publisher","first-page":"6490","DOI":"10.1073\/pnas.0501045102","volume":"102","author":"L Zerboni","year":"2005","unstructured":"Zerboni L, Ku CC, Jones CD, Zehnder JL, Arvin AM (2005) Varicella-zoster virus infection of human dorsal root ganglia in vivo. Proc Natl Acad Sci USA 102:6490\u20136495. doi:10.1073\/pnas.0501045102","journal-title":"Proc Natl Acad Sci USA"}],"container-title":["Journal of NeuroVirology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13365-012-0142-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s13365-012-0142-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s13365-012-0142-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13365-012-0142-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,29]],"date-time":"2022-07-29T12:46:39Z","timestamp":1659098799000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s13365-012-0142-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,12,12]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,2]]}},"alternative-id":["142"],"URL":"https:\/\/doi.org\/10.1007\/s13365-012-0142-x","relation":{},"ISSN":["1355-0284","1538-2443"],"issn-type":[{"value":"1355-0284","type":"print"},{"value":"1538-2443","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,12,12]]},"assertion":[{"value":"6 November 2012","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 November 2012","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 November 2012","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 December 2012","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}