{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T13:26:25Z","timestamp":1762521985609,"version":"3.37.3"},"reference-count":120,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2017,1,23]],"date-time":"2017-01-23T00:00:00Z","timestamp":1485129600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2017,1,23]],"date-time":"2017-01-23T00:00:00Z","timestamp":1485129600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["NS054578","NS066801"],"award-info":[{"award-number":["NS054578","NS066801"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["HL123346"],"award-info":[{"award-number":["HL123346"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J. Neurovirol."],"published-print":{"date-parts":[[2017,6]]},"DOI":"10.1007\/s13365-017-0513-4","type":"journal-article","created":{"date-parts":[[2017,1,23]],"date-time":"2017-01-23T15:48:40Z","timestamp":1485186520000},"page":"347-357","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Preventive and therapeutic challenges in combating Zika virus infection: are we getting any closer?"],"prefix":"10.1007","volume":"23","author":[{"given":"Meera V.","family":"Singh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emily A.","family":"Weber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vir B.","family":"Singh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicole E.","family":"Stirpe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjay B.","family":"Maggirwar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2017,1,23]]},"reference":[{"key":"513_CR1","doi-asserted-by":"publisher","first-page":"1321","DOI":"10.1093\/infdis\/jis180","volume":"205","author":"MT Alonzo","year":"2012","unstructured":"Alonzo MT, Lacuesta TL, Dimaano EM, Kurosu T, Suarez LA, Mapua CA, Akeda Y, Matias RR, Kuter DJ, Nagata S, Natividad FF, Oishi K (2012) Platelet apoptosis and apoptotic platelet clearance by macrophages in secondary dengue virus infections. The Journal of Infectious Diseases 205:1321\u20131329","journal-title":"The Journal of Infectious Diseases"},{"key":"513_CR2","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1186\/s12916-016-0601-y","volume":"14","author":"JM Anaya","year":"2016","unstructured":"Anaya JM, Ramirez-Santana C, Salgado-Castaneda I, Chang C, Ansari A, Gershwin ME (2016) Zika virus and neurologic autoimmunity: the putative role of gangliosides. BMC Medicine 14:49","journal-title":"BMC Medicine"},{"key":"513_CR3","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1590\/0004-282X20160035","volume":"74","author":"LM Araujo","year":"2016","unstructured":"Araujo LM, Ferreira ML, Nascimento OJ (2016) Guillain-Barre syndrome associated with the Zika virus outbreak in Brazil. Arq Neuropsiquiatr 74:253\u2013255","journal-title":"Arq Neuropsiquiatr"},{"key":"513_CR4","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1016\/j.jcv.2016.10.024","volume":"85","author":"RS Azevedo","year":"2016","unstructured":"Azevedo RS, Araujo MT, Martins Filho AJ, Oliveira CS, Nunes BT, Cruz AC, Nascimento AG, Medeiros RC, Caldas CA, Araujo FC, Quaresma JA, Vasconcelos BC, Queiroz MG, da Rosa ES, Henriques DF, Silva EV, Chiang JO, Martins LC, Medeiros DB, Lima JA, Nunes MR, Cardoso JF, Silva SP, Shi PY, Tesh RB, Rodrigues SG, Vasconcelos PF (2016) Zika virus epidemic in Brazil. I. Fatal disease in adults: clinical and laboratorial aspects. J Clin Virol 85:56\u201364","journal-title":"J Clin Virol"},{"key":"513_CR5","doi-asserted-by":"publisher","first-page":"1709","DOI":"10.1227\/NEU.0b013e3181f9b0a5","volume":"67","author":"NC Bambakidis","year":"2010","unstructured":"Bambakidis NC, Wang X, Lukas RJ, Spetzler RF, Sonntag VK, Preul MC (2010) Intravenous hedgehog agonist induces proliferation of neural and oligodendrocyte precursors in rodent spinal cord injury. Neurosurgery 67:1709\u20131715 discussion 1715","journal-title":"Neurosurgery"},{"key":"513_CR6","unstructured":"Barba-Spaeth G, Dejnirattisai W, Rouvinski A, Vaney MC, Medits I, Sharma A, Simon-Loriere E, Sakuntabhai A, Cao-Lormeau VM, Haouz A, England P, Stiasny K, Mongkolsapaya J, Heinz FX, Screaton GR, Rey FA (2016). Structural basis of potent Zika-dengue virus antibody cross-neutralization. Nature."},{"key":"513_CR7","doi-asserted-by":"crossref","unstructured":"Barrows NJ, Campos RK, Powell ST, Prasanth KR, Schott-Lerner G, Soto-Acosta R, Galarza-Munoz G, McGrath EL, Urrabaz-Garza R, Gao J, Wu P, Menon R, Saade G, Fernandez-Salas I, Rossi SL, Vasilakis N, Routh A, Bradrick SS, Garcia-Blanco MA (2016). A screen of FDA-approved drugs for inhibitors of Zika virus infection. Cell host & microbe.","DOI":"10.1016\/j.chom.2016.07.004"},{"key":"513_CR8","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1111\/j.1574-695X.2008.00399.x","volume":"53","author":"A Basu","year":"2008","unstructured":"Basu A, Jain P, Gangodkar SV, Shetty S, Ghosh K (2008) Dengue 2 virus inhibits in vitro megakaryocytic colony formation and induces apoptosis in thrombopoietin-inducible megakaryocytic differentiation from cord blood CD34+ cells. FEMS Immunol Med Microbiol 53:46\u201351","journal-title":"FEMS Immunol Med Microbiol"},{"key":"513_CR9","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1016\/j.chom.2016.03.008","volume":"19","author":"A Bayer","year":"2016","unstructured":"Bayer A, Lennemann NJ, Ouyang Y, Bramley JC, Morosky S, Marques ET Jr, Cherry S, Sadovsky Y, Coyne CB (2016) Type III interferons produced by human placental trophoblasts confer protection against Zika virus infection. Cell Host Microbe 19:705\u2013712","journal-title":"Cell Host Microbe"},{"key":"513_CR10","unstructured":"Besnard M, Eyrolle-Guignot D, Guillemette-Artur P, Lastere S, Bost-Bezeaud F, Marcelis L, Abadie V, Garel C, Moutard ML, Jouannic JM, Rozenberg F, Leparc-Goffart I, Mallet HP (2016). Congenital cerebral malformations and dysfunction in fetuses and newborns following the 2013 to 2014 Zika virus epidemic in French Polynesia. Euro surveillance: bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 21."},{"key":"513_CR11","doi-asserted-by":"publisher","first-page":"1927","DOI":"10.3390\/v7041927","volume":"7","author":"BJ Blitvich","year":"2015","unstructured":"Blitvich BJ, Firth AE (2015) Insect-specific flaviviruses: a systematic review of their discovery, host range, mode of transmission, superinfection exclusion potential and genomic organization. Viruses 7:1927\u20131959","journal-title":"Viruses"},{"key":"513_CR12","doi-asserted-by":"publisher","first-page":"e0004816","DOI":"10.1371\/journal.pntd.0004816","volume":"10","author":"MC Bonaldo","year":"2016","unstructured":"Bonaldo MC, Ribeiro IP, Lima NS, Dos Santos AA, Menezes LS, da Cruz SO, de Mello IS, Furtado ND, de Moura EE, Damasceno L, da Silva KA, de Castro MG, Gerber AL, de Almeida LG, Lourenco-de-Oliveira R, Vasconcelos AT, Brasil P (2016) Isolation of infective Zika virus from urine and saliva of patients in Brazil. PLoS Negl Trop Dis 10:e0004816","journal-title":"PLoS Negl Trop Dis"},{"key":"513_CR13","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1016\/j.neulet.2010.06.068","volume":"482","author":"O Bragina","year":"2010","unstructured":"Bragina O, Sergejeva S, Serg M, Zarkovsky T, Maloverjan A, Kogerman P, Zarkovsky A (2010) Smoothened agonist augments proliferation and survival of neural cells. Neurosci Lett 482:81\u201385","journal-title":"Neurosci Lett"},{"key":"513_CR14","doi-asserted-by":"crossref","unstructured":"Brasil P, Pereira JP, Jr., Raja Gabaglia C, Damasceno L, Wakimoto M, Ribeiro Nogueira RM, Carvalho de Sequeira P, Machado Siqueira A, Abreu de Carvalho LM, Cotrim da Cunha D, Calvet GA, Neves ES, Moreira ME, Rodrigues Baiao AE, Nassar de Carvalho PR, Janzen C, Valderramos SG, Cherry JD, Bispo de Filippis AM, Nielsen-Saines K (2016). Zika virus infection in pregnant women in Rio de Janeiro\u2014preliminary report. The New England journal of medicine.","DOI":"10.1056\/NEJMoa1602412"},{"key":"513_CR15","doi-asserted-by":"crossref","unstructured":"Brault JB, Khou C, Basset J, Coquand L, Fraisier V, Frenkiel MP, Goud B, Manuguerra JC, Pardigon N, Baffet AD (2016). Comparative analysis between flaviviruses reveals specific neural stem cell tropism for Zika virus in the mouse developing neocortex. EBioMedicine.","DOI":"10.1016\/j.ebiom.2016.07.018"},{"key":"513_CR16","doi-asserted-by":"publisher","first-page":"653","DOI":"10.1016\/S1473-3099(16)00095-5","volume":"16","author":"G Calvet","year":"2016","unstructured":"Calvet G, Aguiar RS, Melo AS, Sampaio SA, de Filippis I, Fabri A, Araujo ES, de Sequeira PC, de Mendonca MC, de Oliveira L, Tschoeke DA, Schrago CG, Thompson FL, Brasil P, Dos Santos FB, Nogueira RM, Tanuri A, de Filippis AM (2016) Detection and sequencing of Zika virus from amniotic fluid of fetuses with microcephaly in Brazil: a case study. Lancet Infect Dis 16:653\u2013660","journal-title":"Lancet Infect Dis"},{"key":"513_CR17","doi-asserted-by":"publisher","first-page":"1531","DOI":"10.1016\/S0140-6736(16)00562-6","volume":"387","author":"VM Cao-Lormeau","year":"2016","unstructured":"Cao-Lormeau VM, Blake A, Mons S, Lastere S, Roche C, Vanhomwegen J, Dub T, Baudouin L, Teissier A, Larre P, Vial AL, Decam C, Choumet V, Halstead SK, Willison HJ, Musset L, Manuguerra JC, Despres P, Fournier E, Mallet HP, Musso D, Fontanet A, Neil J, Ghawche F (2016) Guillain-Barre syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study. Lancet 387:1531\u20131539","journal-title":"Lancet"},{"key":"513_CR18","doi-asserted-by":"publisher","first-page":"2125","DOI":"10.1016\/S0140-6736(16)00651-6","volume":"387","author":"S Cauchemez","year":"2016","unstructured":"Cauchemez S, Besnard M, Bompard P, Dub T, Guillemette-Artur P, Eyrolle-Guignot D, Salje H, Van Kerkhove MD, Abadie V, Garel C, Fontanet A, Mallet HP (2016) Association between Zika virus and microcephaly in French Polynesia, 2013\u201315: a retrospective study. Lancet 387:2125\u20132132","journal-title":"Lancet"},{"key":"513_CR19","doi-asserted-by":"crossref","unstructured":"Choi KY, Root M, McGregor A (2016). A novel non-replication competent cytomegalovirus capsid mutant vaccine strategy is effective in reducing congenital infection. Journal of virology.","DOI":"10.1128\/JVI.00283-16"},{"key":"513_CR20","doi-asserted-by":"publisher","first-page":"11418","DOI":"10.1128\/JVI.01257-06","volume":"80","author":"K Clyde","year":"2006","unstructured":"Clyde K, Kyle JL, Harris E (2006) Recent advances in deciphering viral and host determinants of dengue virus replication and pathogenesis. J Virol 80:11418\u201311431","journal-title":"J Virol"},{"key":"513_CR21","doi-asserted-by":"publisher","first-page":"725","DOI":"10.1083\/jcb.201305021","volume":"202","author":"JA Cooper","year":"2013","unstructured":"Cooper JA (2013) Cell biology in neuroscience: mechanisms of cell migration in the nervous system. J Cell Biol 202:725\u2013734","journal-title":"J Cell Biol"},{"key":"513_CR22","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1038\/nature18296","volume":"534","author":"FR Cugola","year":"2016","unstructured":"Cugola FR, Fernandes IR, Russo FB, Freitas BC, Dias JL, Guimaraes KP, Benazzato C, Almeida N, Pignatari GC, Romero S, Polonio CM, Cunha I, Freitas CL, Brandao WN, Rossato C, Andrade DG, Faria Dde P, Garcez AT, Buchpigel CA, Braconi CT, Mendes E, Sall AA, Zanotto PM, Peron JP, Muotri AR, Beltrao-Braga PC (2016) The Brazilian Zika virus strain causes birth defects in experimental models. Nature 534:267\u2013271","journal-title":"Nature"},{"key":"513_CR23","doi-asserted-by":"publisher","first-page":"313842","DOI":"10.1155\/2015\/313842","volume":"2015","author":"EL de Azeredo","year":"2015","unstructured":"de Azeredo EL, Monteiro RQ, de Oliveira Pinto LM (2015) Thrombocytopenia in dengue: interrelationship between virus and the imbalance between coagulation and fibrinolysis and inflammatory mediators. Mediat Inflamm 2015:313842","journal-title":"Mediat Inflamm"},{"key":"513_CR24","doi-asserted-by":"crossref","unstructured":"Dang J, Tiwari SK, Lichinchi G, Qin Y, Patil VS, Eroshkin AM, Rana TM (2016). Zika virus depletes neural progenitors in human cerebral organoids through activation of the innate immune receptor TLR3. Cell stem cell.","DOI":"10.1016\/j.stem.2016.04.014"},{"key":"513_CR25","doi-asserted-by":"publisher","first-page":"2859","DOI":"10.4161\/15384101.2014.946830","volume":"13","author":"A David","year":"2014","unstructured":"David A, Liu F, Tibelius A, Vulprecht J, Wald D, Rothermel U, Ohana R, Seitel A, Metzger J, Ashery-Padan R, Meinzer HP, Grone HJ, Izraeli S, Kramer A (2014) Lack of centrioles and primary cilia in STIL(-\/-) mouse embryos. Cell Cycle 13:2859\u20132868","journal-title":"Cell Cycle"},{"key":"513_CR26","doi-asserted-by":"crossref","unstructured":"Dejnirattisai W, Supasa P, Wongwiwat W, Rouvinski A, Barba-Spaeth G, Duangchinda T, Sakuntabhai A, Cao-Lormeau VM, Malasit P, Rey FA, Mongkolsapaya J, Screaton GR (2016). Dengue virus sero-cross-reactivity drives antibody-dependent enhancement of infection with zika virus. Nature immunology.","DOI":"10.1038\/ni.3515"},{"key":"513_CR27","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1016\/0035-9203(52)90043-6","volume":"46","author":"GW Dick","year":"1952","unstructured":"Dick GW (1952) Zika virus. II. Pathogenicity and physical properties. Trans R Soc Trop Med Hyg 46:521\u2013534","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"513_CR28","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1016\/0035-9203(52)90042-4","volume":"46","author":"GW Dick","year":"1952","unstructured":"Dick GW, Kitchen SF, Haddow AJ (1952) Zika virus. I. Isolations and serological specificity. Trans R Soc Trop Med Hyg 46:509\u2013520","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"513_CR29","doi-asserted-by":"publisher","first-page":"1598","DOI":"10.1056\/NEJMc1609015","volume":"375","author":"T Dos Santos","year":"2016","unstructured":"Dos Santos T, Rodriguez A, Almiron M, Sanhueza A, Ramon P, de Oliveira WK, Coelho GE, Badaro R, Cortez J, Ospina M, Pimentel R, Masis R, Hernandez F, Lara B, Montoya R, Jubithana B, Melchor A, Alvarez A, Aldighieri S, Dye C, Espinal MA (2016) Zika virus and the Guillain-Barre syndrome\u2014case series from seven countries. N Engl J Med 375:1598\u20131601","journal-title":"N Engl J Med"},{"key":"513_CR30","doi-asserted-by":"publisher","first-page":"2142","DOI":"10.1056\/NEJMoa1601824","volume":"374","author":"RW Driggers","year":"2016","unstructured":"Driggers RW, Ho CY, Korhonen EM, Kuivanen S, Jaaskelainen AJ, Smura T, Rosenberg A, Hill DA, DeBiasi RL, Vezina G, Timofeev J, Rodriguez FJ, Levanov L, Razak J, Iyengar P, Hennenfent A, Kennedy R, Lanciotti R, du Plessis A, Vapalahti O (2016) Zika virus infection with prolonged maternal viremia and fetal brain abnormalities. N Engl J Med 374:2142\u20132151","journal-title":"N Engl J Med"},{"key":"513_CR31","doi-asserted-by":"publisher","first-page":"1051","DOI":"10.1016\/S0140-6736(16)00624-3","volume":"387","author":"M Dupont-Rouzeyrol","year":"2016","unstructured":"Dupont-Rouzeyrol M, Biron A, O\u2019Connor O, Huguon E, Descloux E (2016) Infectious Zika viral particles in breastmilk. Lancet 387:1051","journal-title":"Lancet"},{"key":"513_CR32","doi-asserted-by":"publisher","first-page":"35296","DOI":"10.1038\/srep35296","volume":"6","author":"H El Costa","year":"2016","unstructured":"El Costa H, Gouilly J, Mansuy JM, Chen Q, Levy C, Cartron G, Veas F, Al-Daccak R, Izopet J, Jabrane-Ferrat N (2016) ZIKA virus reveals broad tissue and cell tropism during the first trimester of pregnancy. Sci Rep 6:35296","journal-title":"Sci Rep"},{"key":"513_CR33","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jcv.2016.06.011","volume":"82","author":"C Fourcade","year":"2016","unstructured":"Fourcade C, Mansuy JM, Dutertre M, Delpech M, Marchou B, Delobel P, Izopet J, Martin-Blondel G (2016) Viral load kinetics of Zika virus in plasma, urine and saliva in a couple returning from Martinique, French West Indies. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 82:1\u20134","journal-title":"Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology"},{"key":"513_CR34","doi-asserted-by":"crossref","unstructured":"Franca GV, Schuler-Faccini L, Oliveira WK, Henriques CM, Carmo EH, Pedi VD, Nunes ML, Castro MC, Serruya S, Silveira MF, Barros FC, Victora CG (2016). Congenital Zika virus syndrome in Brazil: a case series of the first 1501 livebirths with complete investigation. Lancet.","DOI":"10.1016\/S0140-6736(16)30902-3"},{"key":"513_CR35","doi-asserted-by":"publisher","first-page":"816","DOI":"10.1126\/science.aaf6116","volume":"352","author":"PP Garcez","year":"2016","unstructured":"Garcez PP, Loiola EC, Madeiro da Costa R, Higa LM, Trindade P, Delvecchio R, Nascimento JM, Brindeiro R, Tanuri A, Rehen SK (2016) Zika virus impairs growth in human neurospheres and brain organoids. Science 352:816\u2013818","journal-title":"Science"},{"key":"513_CR36","doi-asserted-by":"publisher","first-page":"3119","DOI":"10.1084\/jem.20082292","volume":"205","author":"D Gaucher","year":"2008","unstructured":"Gaucher D, Therrien R, Kettaf N, Angermann BR, Boucher G, Filali-Mouhim A, Moser JM, Mehta RS, Drake DR 3rd, Castro E, Akondy R, Rinfret A, Yassine-Diab B, Said EA, Chouikh Y, Cameron MJ, Clum R, Kelvin D, Somogyi R, Greller LD, Balderas RS, Wilkinson P, Pantaleo G, Tartaglia J, Haddad EK, Sekaly RP (2008) Yellow fever vaccine induces integrated multilineage and polyfunctional immune responses. J Exp Med 205:3119\u20133131","journal-title":"J Exp Med"},{"key":"513_CR37","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1002\/wdev.89","volume":"2","author":"EC Gilmore","year":"2013","unstructured":"Gilmore EC, Walsh CA (2013) Genetic causes of microcephaly and lessons for neuronal development. Wiley Interdisciplinary Reviews Developmental Biology 2:461\u2013478","journal-title":"Wiley Interdisciplinary Reviews Developmental Biology"},{"key":"513_CR38","doi-asserted-by":"crossref","unstructured":"Halstead SB (2014) Dengue antibody-dependent enhancement: knowns and unknowns. Microbiology Spectrum 2","DOI":"10.1128\/microbiolspec.AID-0022-2014"},{"key":"513_CR39","doi-asserted-by":"publisher","first-page":"8880","DOI":"10.1128\/JVI.00354-15","volume":"89","author":"R Hamel","year":"2015","unstructured":"Hamel R, Dejarnac O, Wichit S, Ekchariyawat P, Neyret A, Luplertlop N, Perera-Lecoin M, Surasombatpattana P, Talignani L, Thomas F, Cao-Lormeau VM, Choumet V, Briant L, Despres P, Amara A, Yssel H, Misse D (2015) Biology of Zika virus infection in human skin cells. J Virol 89:8880\u20138896","journal-title":"J Virol"},{"key":"513_CR40","doi-asserted-by":"crossref","unstructured":"Harrower J, Kiedrzynski T, Baker S, Upton A, Rahnama F, Sherwood J, Huang QS, Todd A, Pulford D (2016) Sexual transmission of Zika virus and persistence in semen, New Zealand, 2016. Emerg Infect Dis 22","DOI":"10.3201\/eid2210.160951"},{"key":"513_CR41","doi-asserted-by":"publisher","first-page":"282ra49","DOI":"10.1126\/scitranslmed.3010286","volume":"7","author":"S He","year":"2015","unstructured":"He S, Lin B, Chu V, Hu Z, Hu X, Xiao J, Wang AQ, Schweitzer CJ, Li Q, Imamura M, Hiraga N, Southall N, Ferrer M, Zheng W, Chayama K, Marugan JJ, Liang TJ (2015) Repurposing of the antihistamine chlorcyclizine and related compounds for treatment of hepatitis C virus infection. Sci Transl Med 7:282ra49","journal-title":"Sci Transl Med"},{"key":"513_CR42","doi-asserted-by":"crossref","first-page":"841","DOI":"10.4269\/ajtmh.2009.80.841","volume":"80","author":"S Honda","year":"2009","unstructured":"Honda S, Saito M, Dimaano EM, Morales PA, Alonzo MT, Suarez LA, Koike N, Inoue S, Kumatori A, Matias RR, Natividad FF, Oishi K (2009) Increased phagocytosis of platelets from patients with secondary dengue virus infection by human macrophages. AmJTrop Med Hyg 80:841\u2013845","journal-title":"AmJTrop Med Hyg"},{"key":"513_CR43","doi-asserted-by":"crossref","unstructured":"Hughes BW, Addanki KC, Sriskanda AN, McLean E, Bagasra O (2016). Infectivity of immature neurons to Zika virus: a link to congenital Zika syndrome. EBioMedicine.","DOI":"10.1016\/j.ebiom.2016.06.026"},{"key":"513_CR44","first-page":"445","volume":"59","author":"PR Hutchings","year":"1986","unstructured":"Hutchings PR, Varey AM, Cooke A (1986) Immunological defects in SJL mice. Immunology 59:445\u2013450","journal-title":"Immunology"},{"key":"513_CR45","doi-asserted-by":"publisher","first-page":"1326","DOI":"10.1016\/j.vaccine.2014.01.040","volume":"32","author":"T Ishikawa","year":"2014","unstructured":"Ishikawa T, Yamanaka A, Konishi E (2014) A review of successful flavivirus vaccines and the problems with those flaviviruses for which vaccines are not yet available. Vaccine 32:1326\u20131337","journal-title":"Vaccine"},{"key":"513_CR46","doi-asserted-by":"crossref","first-page":"2900","DOI":"10.1128\/JCM.36.10.2900-2906.1998","volume":"36","author":"PA Jenum","year":"1998","unstructured":"Jenum PA, Stray-Pedersen B, Melby KK, Kapperud G, Whitelaw A, Eskild A, Eng J (1998) Incidence of toxoplasma gondii infection in 35,940 pregnant women in Norway and pregnancy outcome for infected women. J Clin Microbiol 36:2900\u20132906","journal-title":"J Clin Microbiol"},{"key":"513_CR47","doi-asserted-by":"publisher","first-page":"290ra89","DOI":"10.1126\/scitranslmed.aaa5597","volume":"7","author":"LM Johansen","year":"2015","unstructured":"Johansen LM, DeWald LE, Shoemaker CJ, Hoffstrom BG, Lear-Rooney CM, Stossel A, Nelson E, Delos SE, Simmons JA, Grenier JM, Pierce LT, Pajouhesh H, Lehar J, Hensley LE, Glass PJ, White JM, Olinger GG (2015) A screen of approved drugs and molecular probes identifies therapeutics with anti-Ebola virus activity. Sci Transl Med 7:290ra89","journal-title":"Sci Transl Med"},{"key":"513_CR48","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1056\/NEJMp1605367","volume":"375","author":"MA Johansson","year":"2016","unstructured":"Johansson MA, Mier-y-Teran-Romero L, Reefhuis J, Gilboa SM, Hills SL (2016) Zika and the risk of microcephaly. N Engl J Med 375:1\u20134","journal-title":"N Engl J Med"},{"key":"513_CR49","doi-asserted-by":"publisher","first-page":"939","DOI":"10.1016\/S0140-6736(16)00502-X","volume":"387","author":"O Karimi","year":"2016","unstructured":"Karimi O, Goorhuis A, Schinkel J, Codrington J, Vreden SG, Vermaat JS, Stijnis C, Grobusch MP (2016) Thrombocytopenia and subcutaneous bleedings in a patient with Zika virus infection. Lancet 387:939\u2013940","journal-title":"Lancet"},{"key":"513_CR50","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1038\/nature17994","volume":"533","author":"VA Kostyuchenko","year":"2016","unstructured":"Kostyuchenko VA, Lim EX, Zhang S, Fibriansah G, Ng TS, Ooi JS, Shi J, Lok SM (2016) Structure of the thermally stable Zika virus. Nature 533:425\u2013428","journal-title":"Nature"},{"key":"513_CR51","doi-asserted-by":"crossref","unstructured":"Larocca RA, Abbink P, Peron JP, Zanotto PM, Iampietro MJ, Badamchi-Zadeh A, Boyd M, Ng\u2019ang\u2019a D, Kirilova M, Nityanandam R, Mercado NB, Li Z, Moseley ET, Bricault CA, Borducchi EN, Giglio PB, Jetton D, Neubauer G, Nkolola JP, Maxfield LF, Barrera RA, Jarman RG, Eckels KH, Michael NL, Thomas SJ, Barouch DH (2016). Vaccine protection against Zika virus from Brazil. Nature.","DOI":"10.1038\/nature18952"},{"key":"513_CR52","unstructured":"Leal MC, Muniz LF, Ferreira TS, Santos CM, Almeida LC, Van Der Linden V, Ramos RC, Rodrigues LC, Neto SS (2016). Hearing Loss in Infants with Microcephaly and Evidence of Congenital Zika Virus Infection - Brazil, November 2015-May 2016. MMWR Morb Mortal Wkly Rep 65:917\u20139."},{"key":"513_CR53","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1016\/j.stem.2016.04.017","volume":"19","author":"C Li","year":"2016","unstructured":"Li C, Xu D, Ye Q, Hong S, Jiang Y, Liu X, Zhang N, Shi L, Qin CF, Xu Z (2016a) Zika virus disrupts neural progenitor development and leads to microcephaly in mice. Cell Stem Cell 19:120\u2013126","journal-title":"Cell Stem Cell"},{"key":"513_CR54","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1016\/j.stem.2016.08.005","volume":"19","author":"H Li","year":"2016","unstructured":"Li H, Saucedo-Cuevas L, Regla-Nava JA, Chai G, Sheets N, Tang W, Terskikh AV, Shresta S, Gleeson JG (2016b) Zika virus infects neural progenitors in the adult mouse brain and alters proliferation. Cell Stem Cell 19:593\u2013598","journal-title":"Cell Stem Cell"},{"key":"513_CR55","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1038\/cmi.2015.76","volume":"13","author":"H Liang","year":"2016","unstructured":"Liang H, Lee M, Jin X (2016a) Guiding dengue vaccine development using knowledge gained from the success of the yellow fever vaccine. Cellular & molecular Immunology 13:36\u201346","journal-title":"Cellular & molecular Immunology"},{"key":"513_CR56","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1016\/j.stem.2016.07.019","volume":"19","author":"Q Liang","year":"2016","unstructured":"Liang Q, Luo Z, Zeng J, Chen W, Foo SS, Lee SA, Ge J, Wang S, Goldman SA, Zlokovic BV, Zhao Z, Jung JU (2016b) Zika virus NS4A and NS4B proteins deregulate Akt-mTOR signaling in human fetal neural stem cells to inhibit neurogenesis and induce autophagy. Cell Stem Cell 19:663\u2013671","journal-title":"Cell Stem Cell"},{"key":"513_CR57","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1002\/1096-9071(20000201)63:2<143::AID-JMV1009>3.0.CO;2-L","volume":"63","author":"CF Lin","year":"2001","unstructured":"Lin CF, Lei HY, Liu CC, Liu HS, Yeh TM, Wang ST, Yang TI, Sheu FC, Kuo CF, Lin YS (2001) Generation of IgM anti-platelet autoantibody in dengue patients. J Med Virol 63:143\u2013149","journal-title":"J Med Virol"},{"key":"513_CR58","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1258\/ebm.2011.010339","volume":"236","author":"YS Lin","year":"2011","unstructured":"Lin YS, Yeh TM, Lin CF, Wan SW, Chuang YC, Hsu TK, Liu HS, Liu CC, Anderson R, Lei HY (2011) Molecular mimicry between virus and host and its implications for dengue disease pathogenesis. Exp Biol Med 236:515\u2013523","journal-title":"Exp Biol Med"},{"key":"513_CR59","doi-asserted-by":"crossref","unstructured":"Liuzzi G, Nicastri E, Puro V, Zumla A, Ippolito G (2016). Zika virus in saliva\u2014new challenges for prevention of human to human transmission. European journal of internal medicine.","DOI":"10.1016\/j.ejim.2016.04.022"},{"key":"513_CR60","doi-asserted-by":"publisher","first-page":"937","DOI":"10.1016\/S0896-6273(03)00561-0","volume":"39","author":"R Machold","year":"2003","unstructured":"Machold R, Hayashi S, Rutlin M, Muzumdar MD, Nery S, Corbin JG, Gritli-Linde A, Dellovade T, Porter JA, Rubin LL, Dudek H, McMahon AP, Fishell G (2003) Sonic hedgehog is required for progenitor cell maintenance in telencephalic stem cell niches. Neuron 39:937\u2013950","journal-title":"Neuron"},{"key":"513_CR61","doi-asserted-by":"publisher","first-page":"458","DOI":"10.1016\/j.tmaid.2016.09.006","volume":"14","author":"MC Magalhaes-Barbosa","year":"2016","unstructured":"Magalhaes-Barbosa MC, Prata-Barbosa A, Robaina JR, Raymundo CE, Lima-Setta F, Cunha AJ (2016) Trends of the microcephaly and Zika virus outbreak in Brazil, January\u2013July 2016. Travel Med Infect Dis 14:458\u2013463","journal-title":"Travel Med Infect Dis"},{"key":"513_CR62","doi-asserted-by":"publisher","first-page":"894","DOI":"10.1016\/S1473-3099(16)30153-0","volume":"16","author":"JM Mansuy","year":"2016","unstructured":"Mansuy JM, Pasquier C, Daudin M, Chapuy-Regaud S, Moinard N, Chevreau C, Izopet J, Mengelle C, Bujan L (2016) Zika virus in semen of a patient returning from a non-epidemic area. Lancet Infect Dis 16:894\u2013895","journal-title":"Lancet Infect Dis"},{"key":"513_CR63","doi-asserted-by":"crossref","unstructured":"Martinez-Palomo A (2016). Revisiting Zika (and Rubella). Journal of public health policy.","DOI":"10.1057\/s41271-016-0001-8"},{"key":"513_CR64","unstructured":"Matheron S, D\u2019Ortenzio E, Leparc-Goffart I, Hubert B, de Lamballerie X, Yazdanpanah Y (2016). Long lasting persistence of Zika virus in semen. Clinical infectious diseases: an official publication of the Infectious Diseases Society of America."},{"key":"513_CR65","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1099\/0022-1317-59-1-213","volume":"59","author":"A Mathur","year":"1982","unstructured":"Mathur A, Arora KL, Chaturvedi UC (1982) Transplacental Japanese encephalitis virus (JEV) infection in mice during consecutive pregnancies. The Journal of general virology 59:213\u2013217","journal-title":"The Journal of general virology"},{"key":"513_CR66","first-page":"62","volume":"36","author":"AV Matondang","year":"2004","unstructured":"Matondang AV, Widodo D, Zulkarnain I, Rengganis I, Trihandini I, Inada K, Endo S (2004) The correlation between thrombopoietin and platelet count in adult dengue viral infection patients. Acta medica Indonesiana 36:62\u201369","journal-title":"Acta medica Indonesiana"},{"key":"513_CR67","doi-asserted-by":"publisher","first-page":"211","DOI":"10.15585\/mmwr.mm6508e1","volume":"65","author":"D Meaney-Delman","year":"2016","unstructured":"Meaney-Delman D, Hills SL, Williams C, Galang RR, Iyengar P, Hennenfent AK, Rabe IB, Panella A, Oduyebo T, Honein MA, Zaki S, Lindsey N, Lehman JA, Kwit N, Bertolli J, Ellington S, Igbinosa I, Minta AA, Petersen EE, Mead P, Rasmussen SA, Jamieson DJ (2016) Zika virus infection among U.S. pregnant travelers\u2014August 2015\u2013February 2016. MMWR Morb Mortal Wkly Rep 65:211\u2013214","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"513_CR68","doi-asserted-by":"publisher","first-page":"781","DOI":"10.1016\/S0140-6736(82)92677-0","volume":"2","author":"E Miller","year":"1982","unstructured":"Miller E, Cradock-Watson JE, Pollock TM (1982) Consequences of confirmed maternal rubella at successive stages of pregnancy. Lancet 2:781\u2013784","journal-title":"Lancet"},{"key":"513_CR69","doi-asserted-by":"publisher","first-page":"1081","DOI":"10.1016\/j.cell.2016.05.008","volume":"165","author":"JJ Miner","year":"2016","unstructured":"Miner JJ, Cao B, Govero J, Smith AM, Fernandez E, Cabrera OH, Garber C, Noll M, Klein RS, Noguchi KK, Mysorekar IU, Diamond MS (2016) Zika virus infection during pregnancy in mice causes placental damage and fetal demise. Cell 165:1081\u20131091","journal-title":"Cell"},{"key":"513_CR70","doi-asserted-by":"publisher","first-page":"951","DOI":"10.1056\/NEJMoa1600651","volume":"374","author":"J Mlakar","year":"2016","unstructured":"Mlakar J, Korva M, Tul N, Popovic M, Poljsak-Prijatelj M, Mraz J, Kolenc M, Resman Rus K, Vesnaver Vipotnik T, Fabjan Vodusek V, Vizjak A, Pizem J, Petrovec M, Avsic Zupanc T (2016) Zika virus associated with microcephaly. N Engl J Med 374:951\u2013958","journal-title":"N Engl J Med"},{"key":"513_CR71","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1038\/nrd.2016.159","volume":"15","author":"C Morrison","year":"2016","unstructured":"Morrison C (2016) DNA vaccines against Zika virus speed into clinical trials. Nat Rev Drug Discov 15:521\u2013522","journal-title":"Nat Rev Drug Discov"},{"key":"513_CR72","doi-asserted-by":"crossref","unstructured":"Moshfeghi DM, de Miranda HA, 2nd, Costa MC (2016). Zika virus, microcephaly, and ocular findings. JAMA ophthalmology.","DOI":"10.1001\/jamaophthalmol.2016.1303"},{"key":"513_CR73","doi-asserted-by":"crossref","unstructured":"Muller JA, Harms M, Schubert A, Jansen S, Michel D, Mertens T, Schmidt-Chanasit J, Munch J (2016) Inactivation and environmental stability of Zika virus. Emerg Infect Dis 22","DOI":"10.3201\/eid2209.160664"},{"key":"513_CR74","doi-asserted-by":"publisher","first-page":"1497","DOI":"10.1086\/516486","volume":"175","author":"B Murgue","year":"1997","unstructured":"Murgue B, Cassar O, Guigon M, Chungue E (1997) Dengue virus inhibits human hematopoietic progenitor growth in vitro. The Journal of infectious diseases 175:1497\u20131501","journal-title":"The Journal of infectious diseases"},{"key":"513_CR75","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1182\/blood.V74.4.1235.bloodjournal7441235","volume":"74","author":"S Nakao","year":"1989","unstructured":"Nakao S, Lai CJ, Young NS (1989) Dengue virus, a flavivirus, propagates in human bone marrow progenitors and hematopoietic cell lines. Blood 74:1235\u20131240","journal-title":"Blood"},{"key":"513_CR76","doi-asserted-by":"publisher","first-page":"591","DOI":"10.1016\/j.stem.2016.03.012","volume":"18","author":"TJ Nowakowski","year":"2016","unstructured":"Nowakowski TJ, Pollen AA, Di Lullo E, Sandoval-Espinosa C, Bershteyn M, Kriegstein AR (2016) Expression analysis highlights AXL as a candidate Zika virus entry receptor in neural stem cells. Cell Stem Cell 18:591\u2013596","journal-title":"Cell Stem Cell"},{"key":"513_CR77","doi-asserted-by":"crossref","unstructured":"Pacheco O, Beltran M, Nelson CA, Valencia D, Tolosa N, Farr SL, Padilla AV, Tong VT, Cuevas EL, Espinosa-Bode A, Pardo L, Rico A, Reefhuis J, Gonzalez M, Mercado M, Chaparro P, Martinez Duran M, Rao CY, Munoz MM, Powers AM, Cuellar C, Helfand R, Huguett C, Jamieson DJ, Honein MA, Ospina Martinez ML (2016). Zika virus disease in Colombia\u2014preliminary report. The New England journal of medicine.","DOI":"10.1056\/NEJMoa1604037"},{"key":"513_CR78","doi-asserted-by":"crossref","unstructured":"Parke DW, 3rd, Almeida DR, Albini TA, Ventura CV, Berrocal AM, Mittra RA (2016). Serologically confirmed Zika-related unilateral acute maculopathy in an adult. Ophthalmology.","DOI":"10.1016\/j.ophtha.2016.06.039"},{"key":"513_CR79","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1016\/j.jcv.2005.09.015","volume":"35","author":"RF Pass","year":"2006","unstructured":"Pass RF, Fowler KB, Boppana SB, Britt WJ, Stagno S (2006) Congenital cytomegalovirus infection following first trimester maternal infection: symptoms at birth and outcome. Journal of clinical virology: the official publication of the Pan American Society for Clinical Virology 35:216\u2013220","journal-title":"Journal of clinical virology: the official publication of the Pan American Society for Clinical Virology"},{"key":"513_CR80","doi-asserted-by":"publisher","first-page":"7852","DOI":"10.1073\/pnas.1607931113","volume":"113","author":"L Priyamvada","year":"2016","unstructured":"Priyamvada L, Quicke KM, Hudson WH, Onlamoon N, Sewatanon J, Edupuganti S, Pattanapanyasat K, Chokephaibulkit K, Mulligan MJ, Wilson PC, Ahmed R, Suthar MS, Wrammert J (2016) Human antibody responses after dengue virus infection are highly cross-reactive to Zika virus. Proc Natl Acad Sci U S A 113:7852\u20137857","journal-title":"Proc Natl Acad Sci U S A"},{"key":"513_CR81","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1038\/nri2629","volume":"9","author":"B Pulendran","year":"2009","unstructured":"Pulendran B (2009) Learning immunology from the yellow fever vaccine: innate immunity to systems vaccinology. Nat Rev Immunol 9:741\u2013747","journal-title":"Nat Rev Immunol"},{"key":"513_CR82","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1111\/imr.12099","volume":"255","author":"B Pulendran","year":"2013","unstructured":"Pulendran B, Oh JZ, Nakaya HI, Ravindran R, Kazmin DA (2013) Immunity to viruses: learning from successful human vaccines. Immunol Rev 255:243\u2013255","journal-title":"Immunol Rev"},{"key":"513_CR83","doi-asserted-by":"publisher","first-page":"828","DOI":"10.3201\/eid2205.160290","volume":"22","author":"J Reefhuis","year":"2016","unstructured":"Reefhuis J, Gilboa SM, Johansson MA, Valencia D, Simeone RM, Hills SL, Polen K, Jamieson DJ, Petersen LR, Honein MA (2016) Projecting month of birth for at-risk infants after Zika virus disease outbreaks. Emerg Infect Dis 22:828\u2013832","journal-title":"Emerg Infect Dis"},{"key":"513_CR84","unstructured":"Reusken C, Pas S, GeurtsvanKessel C, Mogling R, van Kampen J, Langerak T, Koopmans M, van der Eijk A, van Gorp E (2016). Longitudinal follow-up of Zika virus RNA in semen of a traveller returning from Barbados to the Netherlands with Zika virus disease, March 2016. Euro surveillance: bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 21."},{"key":"513_CR85","doi-asserted-by":"publisher","first-page":"14682","DOI":"10.1073\/pnas.1508095112","volume":"112","author":"AS Richard","year":"2015","unstructured":"Richard AS, Zhang A, Park SJ, Farzan M, Zong M, Choe H (2015) Virion-associated phosphatidylethanolamine promotes TIM1-mediated infection by Ebola, dengue, and West Nile viruses. Proc Natl Acad Sci U S A 112:14682\u201314687","journal-title":"Proc Natl Acad Sci U S A"},{"key":"513_CR86","doi-asserted-by":"publisher","first-page":"540","DOI":"10.1097\/WCO.0b013e32830b84b7","volume":"21","author":"S Rinaldi","year":"2008","unstructured":"Rinaldi S, Willison HJ (2008) Ganglioside antibodies and neuropathies. Curr Opin Neurol 21:540\u2013546","journal-title":"Curr Opin Neurol"},{"key":"513_CR87","doi-asserted-by":"publisher","first-page":"847","DOI":"10.1016\/S0140-6736(16)30930-8","volume":"388","author":"DJ Roberts","year":"2016","unstructured":"Roberts DJ, Frosch MP (2016) Zika and histopathology in first trimester infections. Lancet 388:847\u2013849","journal-title":"Lancet"},{"key":"513_CR88","doi-asserted-by":"publisher","first-page":"2773","DOI":"10.1007\/s00018-010-0357-z","volume":"67","author":"IA Rodenhuis-Zybert","year":"2010","unstructured":"Rodenhuis-Zybert IA, Wilschut J, Smit JM (2010) Dengue virus life cycle: viral and host factors modulating infectivity. Cellular and molecular life sciences : CMLS 67:2773\u20132786","journal-title":"Cellular and molecular life sciences : CMLS"},{"key":"513_CR89","doi-asserted-by":"publisher","first-page":"1362","DOI":"10.4269\/ajtmh.16-0111","volume":"94","author":"SL Rossi","year":"2016","unstructured":"Rossi SL, Tesh RB, Azar SR, Muruato AE, Hanley KA, Auguste AJ, Langsjoen RM, Paessler S, Vasilakis N, Weaver SC (2016) Characterization of a novel murine model to study Zika virus. AmJTrop Med Hyg 94:1362\u20131369","journal-title":"AmJTrop Med Hyg"},{"key":"513_CR90","unstructured":"Roze B, Najioullah F, Ferge JL, Apetse K, Brouste Y, Cesaire R, Fagour C, Fagour L, Hochedez P, Jeannin S, Joux J, Mehdaoui H, Valentino R, Signate A, Cabie A (2016). Zika virus detection in urine from patients with Guillain-Barre syndrome on Martinique, January 2016. Euro surveillance: bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 21."},{"key":"513_CR91","doi-asserted-by":"crossref","unstructured":"Sapparapu G, Fernandez E, Kose N, Cao B, Fox JM, Bombardi RG, Zhao H, Nelson CA, Bryan AL, Barnes T, Davidson E, Mysorekar IU, Fremont DH, Doranz BJ, Diamond MS, Crowe JE (2016). Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice. Nature.","DOI":"10.1038\/nature20564"},{"key":"513_CR92","doi-asserted-by":"publisher","first-page":"e0004517","DOI":"10.1371\/journal.pntd.0004517","volume":"10","author":"M Sarno","year":"2016","unstructured":"Sarno M, Sacramento GA, Khouri R, do Rosario MS, Costa F, Archanjo G, Santos LA, Nery N Jr, Vasilakis N, Ko AI, de Almeida AR (2016) Zika virus infection and stillbirths: a case of hydrops fetalis, hydranencephaly and fetal demise. PLoS Negl Trop Dis 10:e0004517","journal-title":"PLoS Negl Trop Dis"},{"key":"513_CR93","doi-asserted-by":"publisher","first-page":"59","DOI":"10.15585\/mmwr.mm6503e2","volume":"65","author":"L Schuler-Faccini","year":"2016","unstructured":"Schuler-Faccini L, Ribeiro EM, Feitosa IM, Horovitz DD, Cavalcanti DP, Pessoa A, Doriqui MJ, Neri JI, Neto JM, Wanderley HY, Cernach M, El-Husny AS, Pone MV, Serao CL, Sanseverino MT (2016) Possible association between Zika virus infection and microcephaly\u2014Brazil, 2015. MMWR Morb Mortal Wkly Rep 65:59\u201362","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"513_CR94","doi-asserted-by":"publisher","first-page":"745","DOI":"10.1038\/nri3916","volume":"15","author":"G Screaton","year":"2015","unstructured":"Screaton G, Mongkolsapaya J, Yacoub S, Roberts C (2015) New insights into the immunopathology and control of dengue virus infection. Nat Rev Immunol 15:745\u2013759","journal-title":"Nat Rev Immunol"},{"key":"513_CR95","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1177\/0300985811429314","volume":"49","author":"RS Sellers","year":"2012","unstructured":"Sellers RS, Clifford CB, Treuting PM, Brayton C (2012) Immunological variation between inbred laboratory mouse strains: points to consider in phenotyping genetically immunomodified mice. Vet Pathol 49:32\u201343","journal-title":"Vet Pathol"},{"key":"513_CR96","unstructured":"Sharp TM, Munoz-Jordan J, Perez-Padilla J, Bello-Pagan MI, Rivera A, Pastula DM, Salinas JL, Martinez Mendez JH, Mendez M, Powers AM, Waterman S, Rivera-Garcia B (2016). Zika virus infection associated with severe thrombocytopenia. Clinical infectious diseases: an official publication of the Infectious Diseases Society of America."},{"key":"513_CR97","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1016\/j.vaccine.2010.08.046","volume":"29","author":"ML Silva","year":"2011","unstructured":"Silva ML, Martins MA, Espirito-Santo LR, Campi-Azevedo AC, Silveira-Lemos D, Ribeiro JG, Homma A, Kroon EG, Teixeira-Carvalho A, Eloi-Santos SM, Martins-Filho OA (2011) Characterization of main cytokine sources from the innate and adaptive immune responses following primary 17DD yellow fever vaccination in adults. Vaccine 29:583\u2013592","journal-title":"Vaccine"},{"key":"513_CR98","doi-asserted-by":"publisher","first-page":"26876","DOI":"10.1038\/srep26876","volume":"6","author":"VB Singh","year":"2016","unstructured":"Singh VB, Singh MV, Gorantla S, Poluektova LY, Maggirwar SB (2016) Smoothened agonist reduces human immunodeficiency virus type-1-induced blood-brain barrier breakdown in humanized mice. Sci Rep 6:26876","journal-title":"Sci Rep"},{"key":"513_CR99","doi-asserted-by":"crossref","unstructured":"Soares de Souza A, Moraes Dias C, Braga FD, Terzian AC, Estofolete CF, Oliani AH, Oliveira GH, Brandao de Mattos CC, de Mattos LC, Nogueira ML, Vaz-Oliani DC (2016). Fetal infection by Zika virus in the third trimester: report of 2 cases. Clin Infect Dis.","DOI":"10.1093\/cid\/ciw613"},{"key":"513_CR100","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1016\/j.cell.2005.04.028","volume":"122","author":"KL Spalding","year":"2005","unstructured":"Spalding KL, Bhardwaj RD, Buchholz BA, Druid H, Frisen J (2005) Retrospective birth dating of cells in humans. Cell 122:133\u2013143","journal-title":"Cell"},{"key":"513_CR101","first-page":"19","volume":"20","author":"T Srichaikul","year":"1989","unstructured":"Srichaikul T, Nimmannitya S, Sripaisarn T, Kamolsilpa M, Pulgate C (1989) Platelet function during the acute phase of dengue hemorrhagic fever. The Southeast Asian journal of tropical medicine and public health 20:19\u201325","journal-title":"The Southeast Asian journal of tropical medicine and public health"},{"key":"513_CR102","doi-asserted-by":"crossref","unstructured":"Stettler K, Beltramello M, Espinosa DA, Graham V, Cassotta A, Bianchi S, Vanzetta F, Minola A, Jaconi S, Mele F, Foglierini M, Pedotti M, Simonelli L, Dowall S, Atkinson B, Percivalle E, Simmons CP, Varani L, Blum J, Baldanti F, Cameroni E, Hewson R, Harris E, Lanzavecchia A, Sallusto F, Corti D (2016). Specificity, cross-reactivity and function of antibodies elicited by Zika virus infection. Science.","DOI":"10.1126\/science.aaf8505"},{"key":"513_CR103","unstructured":"Strafela P, Vizjak A, Mraz J, Mlakar J, Pizem J, Tul N, Zupanc TA, Popovic M (2016). Zika virus-associated micrencephaly: a thorough description of neuropathologic findings in the fetal central nervous system. Arch Pathol Lab Med."},{"key":"513_CR104","doi-asserted-by":"crossref","unstructured":"Swanstrom JA, Plante JA, Plante KS, Young EF, McGowan E, Gallichotte EN, Widman DG, Heise MT, de Silva AM, Baric RS (2016). Dengue virus envelope dimer epitope monoclonal antibodies isolated from dengue patients are protective against Zika virus. mBio 7.","DOI":"10.1128\/mBio.01123-16"},{"key":"513_CR105","doi-asserted-by":"crossref","unstructured":"Tabata T, Petitt M, Puerta-Guardo H, Michlmayr D, Wang C, Fang-Hoover J, Harris E, Pereira L (2016). Zika virus targets different primary human placental cells, suggesting two routes for vertical transmission. Cell host & microbe.","DOI":"10.1016\/j.chom.2016.07.002"},{"key":"513_CR106","doi-asserted-by":"publisher","first-page":"587","DOI":"10.1016\/j.stem.2016.02.016","volume":"18","author":"H Tang","year":"2016","unstructured":"Tang H, Hammack C, Ogden SC, Wen Z, Qian X, Li Y, Yao B, Shin J, Zhang F, Lee EM, Christian KM, Didier RA, Jin P, Song H, Ming GL (2016) Zika virus infects human cortical neural progenitors and attenuates their growth. Cell Stem Cell 18:587\u2013590","journal-title":"Cell Stem Cell"},{"key":"513_CR107","doi-asserted-by":"publisher","first-page":"2501","DOI":"10.1016\/S0140-6736(16)30775-9","volume":"387","author":"JM Turmel","year":"2016","unstructured":"Turmel JM, Abgueguen P, Hubert B, Vandamme YM, Maquart M, Le Guillou-Guillemette H, Leparc-Goffart I (2016) Late sexual transmission of Zika virus related to persistence in the semen. Lancet 387:2501","journal-title":"Lancet"},{"key":"513_CR108","doi-asserted-by":"publisher","first-page":"1002","DOI":"10.1056\/NEJMc1605898","volume":"375","author":"AA van der Eijk","year":"2016","unstructured":"van der Eijk AA, van Genderen PJ, Verdijk RM, Reusken CB, Mogling R, van Kampen JJ, Widagdo W, Aron GI, GeurtsvanKessel CH, Pas SD, Raj VS, Haagmans BL, Koopmans MP (2016) Miscarriage associated with Zika virus infection. N Engl J Med 375:1002\u20131004","journal-title":"N Engl J Med"},{"key":"513_CR109","doi-asserted-by":"crossref","unstructured":"Valentine G, Marquez L, Pammi M (2016). Zika virus-associated microcephaly and eye lesions in the newborn. Journal of the Pediatric Infectious Diseases Society.","DOI":"10.1093\/jpids\/piw037"},{"key":"513_CR110","doi-asserted-by":"publisher","first-page":"2502","DOI":"10.1016\/S0140-6736(16)30776-0","volume":"387","author":"CV Ventura","year":"2016","unstructured":"Ventura CV, Maia M, Dias N, Ventura LO, Belfort R Jr (2016) Zika: neurological and ocular findings in infant without microcephaly. Lancet 387:2502","journal-title":"Lancet"},{"key":"513_CR111","doi-asserted-by":"publisher","unstructured":"Vinhaes ES, Santos LA, Dias L, Andrade NA, Bezerra VH, de Carvalho AT, de Moraes L, Henriques DF, Azar SR, Vasilakis N, Ko AI, Andrade BB, Siqueira IC, Khouri R, Boaventura VS (2016). Transient Hearing Loss in Adults Associated with Zika Virus Infection. Clin Infect Dis. doi:\n                    10.1093\/cid\/ciw770","DOI":"10.1093\/cid\/ciw770"},{"key":"513_CR112","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/j.antiviral.2016.03.010","volume":"130","author":"SC Weaver","year":"2016","unstructured":"Weaver SC, Costa F, Garcia-Blanco MA, Ko AI, Ribeiro GS, Saade G, Shi PY, Vasilakis N (2016) Zika virus: history, emergence, biology, and prospects for control. Antivir Res 130:69\u201380","journal-title":"Antivir Res"},{"key":"513_CR113","doi-asserted-by":"crossref","unstructured":"White MK, Wollebo HS, Beckham JD, Tyler KL, Khalili K (2016). Zika virus: an emergent neuropathological agent. Annals of neurology.","DOI":"10.1002\/ana.24748"},{"key":"513_CR114","unstructured":"WHO (2016a). Current Zika product pipeline."},{"key":"513_CR115","unstructured":"WHO (2016b) Dengue vaccine: WHO position paper. World Health Organization:349\u2013364"},{"issue":"Suppl 1","key":"513_CR116","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1111\/j.1471-4159.2007.04718.x","volume":"103","author":"HJ Willison","year":"2007","unstructured":"Willison HJ (2007) Gangliosides as targets for autoimmune injury to the nervous system. J Neurochem 103(Suppl 1):143\u2013149","journal-title":"J Neurochem"},{"key":"513_CR117","doi-asserted-by":"crossref","unstructured":"Wiwanitkit V (2016). Zika virus infection spread through saliva. Brazilian oral research 30.","DOI":"10.1590\/1807-3107BOR-2016.vol30.0076"},{"key":"513_CR118","doi-asserted-by":"publisher","first-page":"1101","DOI":"10.1038\/nm.4184","volume":"22","author":"M Xu","year":"2016","unstructured":"Xu M, Lee EM, Wen Z, Cheng Y, Huang WK, Qian X, Tcw J, Kouznetsova J, Ogden SC, Hammack C, Jacob F, Nguyen HN, Itkin M, Hanna C, Shinn P, Allen C, Michael SG, Simeonov A, Huang W, Christian KM, Goate A, Brennand KJ, Huang R, Xia M, Ming GL, Zheng W, Song H, Tang H (2016) Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen. Nat Med 22:1101\u20131107","journal-title":"Nat Med"},{"key":"513_CR119","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1016\/j.devcel.2015.01.019","volume":"32","author":"Y Yamaguchi","year":"2015","unstructured":"Yamaguchi Y, Miura M (2015) Programmed cell death in neurodevelopment. Dev Cell 32:478\u2013490","journal-title":"Dev Cell"},{"key":"513_CR120","doi-asserted-by":"crossref","unstructured":"Zhao H, Fernandez E, Dowd KA, Speer SD, Platt DJ, Gorman MJ, Govero J, Nelson CA, Pierson TC, Diamond MS, Fremont DH (2016). Structural basis of Zika virus-specific antibody protection. Cell.","DOI":"10.1016\/j.cell.2016.07.020"}],"container-title":["Journal of NeuroVirology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s13365-017-0513-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s13365-017-0513-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s13365-017-0513-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,16]],"date-time":"2020-05-16T22:03:24Z","timestamp":1589666604000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s13365-017-0513-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1,23]]},"references-count":120,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,6]]}},"alternative-id":["513"],"URL":"https:\/\/doi.org\/10.1007\/s13365-017-0513-4","relation":{},"ISSN":["1355-0284","1538-2443"],"issn-type":[{"type":"print","value":"1355-0284"},{"type":"electronic","value":"1538-2443"}],"subject":[],"published":{"date-parts":[[2017,1,23]]},"assertion":[{"value":"23 November 2016","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 January 2017","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 January 2017","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}