{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T22:16:18Z","timestamp":1792188978451,"version":"4.4.0"},"reference-count":115,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2019,1,11]],"date-time":"2019-01-11T00:00:00Z","timestamp":1547164800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1105808"],"award-info":[{"award-number":["APP1105808"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP568746"],"award-info":[{"award-number":["APP568746"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1045400"],"award-info":[{"award-number":["APP1045400"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J. Neurovirol."],"published-print":{"date-parts":[[2019,10]]},"DOI":"10.1007\/s13365-018-0706-5","type":"journal-article","created":{"date-parts":[[2019,1,11]],"date-time":"2019-01-11T13:22:47Z","timestamp":1547212967000},"page":"710-721","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":78,"title":["Vascular cognitive impairment and HIV-associated neurocognitive disorder: a new paradigm"],"prefix":"10.1007","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7711-6373","authenticated-orcid":false,"given":"Lucette A.","family":"Cysique","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce J.","family":"Brew","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,1,11]]},"reference":[{"key":"706_CR1","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1016\/j.brainresbull.2018.05.018","volume":"145","author":"Rufus O. Akinyemi","year":"2019","unstructured":"Akinyemi RO, Owolabi MO, Ihara M, Damasceno A, Ogunniyi A, Dotchin C, Paddick SM, Ogeng'o J, Walker R, Kalaria RN (2018) Stroke, cerebrovascular diseases and vascular cognitive impairment in Africa. Brain Res Bull. https:\/\/doi.org\/10.1016\/j.brainresbull.2018.05.018","journal-title":"Brain Research Bulletin"},{"key":"706_CR2","doi-asserted-by":"publisher","first-page":"627","DOI":"10.1093\/cid\/ciu869","volume":"60","author":"KN Althoff","year":"2015","unstructured":"Althoff KN, McGinnis KA, Wyatt CM, Freiberg MS, Gilbert C, Oursler KK, Rimland D, Rodriguez-Barradas MC, Dubrow R, Park LS, Skanderson M, Shiels MS, Gange SJ, Gebo KA, Justice AC (2015) Comparison of risk and age at diagnosis of myocardial infarction, end-stage renal disease, and non-AIDS-defining cancer in HIV-infected versus uninfected adults. Clin Infect Dis 60:627\u2013638","journal-title":"Clin Infect Dis"},{"key":"706_CR3","doi-asserted-by":"publisher","first-page":"1789","DOI":"10.1212\/01.WNL.0000287431.88658.8b","volume":"69","author":"A Antinori","year":"2007","unstructured":"Antinori A, Arendt G, Becker JT, Brew BJ, Byrd DA, Cherner M, Clifford DB, Cinque P, Epstein LG, Goodkin K, Gisslen M, Grant I, Heaton RK, Joseph J, Marder K, Marra CM, McArthur JC, Nunn M, Price RW, Pulliam L, Robertson KR, Sacktor N, Valcour V, Wojna VE (2007) Updated research nosology for HIV-associated neurocognitive disorders. Neurology 69:1789\u20131799","journal-title":"Neurology"},{"key":"706_CR4","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1002\/path.2276","volume":"214","author":"V Appay","year":"2008","unstructured":"Appay V, Sauce D (2008) Immune activation and inflammation in HIV-1 infection: causes and consequences. J Pathol 214:231\u2013241","journal-title":"J Pathol"},{"key":"706_CR5","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1080\/21505594.2016.1195536","volume":"8","author":"V Appay","year":"2017","unstructured":"Appay V, Sauce D (2017) Assessing immune aging in HIV-infected patients. Virulence 8:529\u2013538","journal-title":"Virulence"},{"key":"706_CR6","doi-asserted-by":"publisher","first-page":"212","DOI":"10.3389\/fncel.2015.00212","volume":"9","author":"VS Atluri","year":"2015","unstructured":"Atluri VS, Hidalgo M, Samikkannu T, Kurapati KR, Jayant RD, Sagar V, Nair MP (2015) Effect of human immunodeficiency virus on blood-brain barrier integrity and function: an update. Front Cell Neurosci 9:212","journal-title":"Front Cell Neurosci"},{"key":"706_CR7","first-page":"82","volume":"19","author":"M Bachani","year":"2013","unstructured":"Bachani M, Sacktor N, McArthur JC, Nath A, Rumbaugh J (2013) Detection of anti-tat antibodies in CSF of individuals with HIV-associated neurocognitive disorders. J Neuro-Oncol 19:82\u201388","journal-title":"J Neuro-Oncol"},{"key":"706_CR8","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1007\/s11883-017-0652-3","volume":"19","author":"RP Barnes","year":"2017","unstructured":"Barnes RP, Lacson JC, Bahrami H (2017) HIV infection and risk of cardiovascular diseases beyond coronary artery disease. Curr Atheroscler Rep 19:20","journal-title":"Curr Atheroscler Rep"},{"key":"706_CR9","doi-asserted-by":"publisher","DOI":"10.1212\/NXI.0000000000000254","volume":"3","author":"LA Benjamin","year":"2016","unstructured":"Benjamin LA, Bryer A, Lucas S, Stanley A, Allain TJ, Joekes E, Emsley H, Turnbull I, Downey C, Toh CH, Brown K, Brown D, Ison C, Smith C, Corbett EL, Nath A, Heyderman RS, Connor MD, Solomon T (2016) Arterial ischemic stroke in HIV: defining and classifying etiology for research studies. Neurol Neuroimmunol Neuroinflamm 3:e254","journal-title":"Neurol Neuroimmunol Neuroinflamm"},{"key":"706_CR10","doi-asserted-by":"publisher","first-page":"715","DOI":"10.1042\/CS20160452","volume":"131","author":"JM Biesbroek","year":"2017","unstructured":"Biesbroek JM, Weaver NA, Biessels GJ (2017) Lesion location and cognitive impact of cerebral small vessel disease. Clin Sci (Lond) 131:715\u2013728","journal-title":"Clin Sci (Lond)"},{"key":"706_CR11","doi-asserted-by":"publisher","first-page":"52","DOI":"10.2174\/1874613601711010052","volume":"11","author":"R Bijker","year":"2017","unstructured":"Bijker R, Choi JY, Ditangco R, Kiertiburanakul S, Lee MP, Siwamogsatham S, Pujari S, Ross J, Wong C, Wong WW, Yunihastuti E, Law M (2017) Cardiovascular disease and cardiovascular disease risk in HIV-positive populations in the Asian region. Open AIDS J 11:52\u201366","journal-title":"Open AIDS J"},{"key":"706_CR12","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000005891","volume":"96","author":"C Blokhuis","year":"2017","unstructured":"Blokhuis C, Mutsaerts HJ, Cohen S, Scherpbier HJ, Caan MW, Majoie CB, Kuijpers TW, Reiss P, Wit FW, Pajkrt D (2017) Higher subcortical and white matter cerebral blood flow in perinatally HIV-infected children. Medicine (Baltimore) 96:e5891","journal-title":"Medicine (Baltimore)"},{"key":"706_CR13","doi-asserted-by":"publisher","first-page":"1814","DOI":"10.1212\/WNL.50.6.1814","volume":"50","author":"FH Bouwman","year":"1998","unstructured":"Bouwman FH, Skolasky RL, Hes D, Selnes OA, Glass JD, Nance-Sproson TE, Royal W, Dal Pan GJ, McArthur JC (1998) Variable progression of HIV-associated dementia. Neurology 50:1814\u20131820","journal-title":"Neurology"},{"key":"706_CR14","doi-asserted-by":"publisher","first-page":"2379","DOI":"10.1097\/QAD.0000000000001225","volume":"30","author":"BJ Brew","year":"2016","unstructured":"Brew BJ (2016) Has HIV-associated neurocognitive disorders now transformed into vascular cognitive impairment? AIDS 30:2379\u20132380","journal-title":"AIDS"},{"key":"706_CR15","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1007\/s11481-008-9143-1","volume":"4","author":"BJ Brew","year":"2009","unstructured":"Brew BJ, Crowe SM, Landay A, Cysique LA, Guillemin G (2009) Neurodegeneration and ageing in the HAART era. J NeuroImmune Pharmacol 4:163\u2013174","journal-title":"J NeuroImmune Pharmacol"},{"key":"706_CR16","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1089\/aid.2015.0328","volume":"32","author":"SJ Brunt","year":"2016","unstructured":"Brunt SJ, Cysique LA, Lee S, Burrows S, Brew BJ, Price P (2016) Short communication: do cytomegalovirus antibody levels associate with age-related syndromes in HIV patients stable on antiretroviral therapy? AIDS Res Hum Retrovir 32:567\u2013572","journal-title":"AIDS Res Hum Retrovir"},{"key":"706_CR17","doi-asserted-by":"publisher","first-page":"e393","DOI":"10.1161\/CIR.0000000000000534","volume":"136","author":"MR Carnethon","year":"2017","unstructured":"Carnethon MR, Pu J, Howard G, Albert MA, Anderson CAM, Bertoni AG, Mujahid MS, Palaniappan L, Taylor HA Jr, Willis M, Yancy CW (2017) Cardiovascular health in African Americans: a scientific statement from the American Heart Association. Circulation 136:e393\u2013e423","journal-title":"Circulation"},{"key":"706_CR18","doi-asserted-by":"publisher","first-page":"1154","DOI":"10.1016\/j.jstrokecerebrovasdis.2017.02.010","volume":"26","author":"FC Chow","year":"2017","unstructured":"Chow FC, Price RW, Hsue PY, Kim AS (2017) Greater risk of stroke of undetermined etiology in a contemporary HIV-infected cohort compared with uninfected individuals. J Stroke Cerebrovasc Dis 26:1154\u20131160","journal-title":"J Stroke Cerebrovasc Dis"},{"key":"706_CR19","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1097\/QAI.0b013e31825c7f24","volume":"60","author":"FC Chow","year":"2012","unstructured":"Chow FC, Regan S, Feske S, Meigs JB, Grinspoon SK, Triant VA (2012) Comparison of ischemic stroke incidence in HIV-infected and non-HIV-infected patients in a US health care system. J Acquir Immune Defic Syndr 60:351\u2013358","journal-title":"J Acquir Immune Defic Syndr"},{"key":"706_CR20","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1503\/cjs.013917","volume":"61","author":"B Christopher","year":"2018","unstructured":"Christopher B, Nadine RC, Mohamad AH, Ahmed K, Subodh V, Mohammed AO (2018) Peripheral artery disease among indigenous Canadians: what do we know? Can J Surg 61:305\u2013310","journal-title":"Can J Surg"},{"key":"706_CR21","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1097\/QAI.0000000000001489","volume":"76","author":"KM Clifford","year":"2017","unstructured":"Clifford KM, Samboju V, Cobigo Y, Milanini B, Marx GA, Hellmuth JM, Rosen HJ, Kramer JH, Allen IE, Valcour VG (2017) Progressive brain atrophy despite persistent viral suppression in HIV patients older than 60 years. J Acquir Immune Defic Syndr 76:289\u2013297","journal-title":"J Acquir Immune Defic Syndr"},{"key":"706_CR22","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1016\/j.nbd.2016.01.011","volume":"92","author":"SL Cody","year":"2016","unstructured":"Cody SL, Vance DE (2016) The neurobiology of HIV and its impact on cognitive reserve: a review of cognitive interventions for an aging population. Neurobiol Dis 92:144\u2013156","journal-title":"Neurobiol Dis"},{"key":"706_CR23","doi-asserted-by":"publisher","first-page":"1349","DOI":"10.1212\/WNL.0000000000003790","volume":"88","author":"JH Cole","year":"2017","unstructured":"Cole JH, Underwood J, Caan MW, De Francesco D, van Zoest RA, Leech R, Wit FW, Portegies P, Geurtsen GJ, Schmand BA, Schim van der Loeff MF, Franceschi C, Sabin CA, Majoie CB, Winston A, Reiss P, Sharp DJ (2017) Increased brain-predicted aging in treated HIV disease. Neurology 88:1349\u20131357","journal-title":"Neurology"},{"key":"706_CR24","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1080\/09540121.2018.1426826","volume":"30","author":"D Cummins","year":"2018","unstructured":"Cummins D, Waters D, Aggar C, Crawford D, Fethney J, O'Connor C (2018) Voices from Australia\u2014concerns about HIV associated neurocognitive disorder. AIDS Care 30:609\u2013617","journal-title":"AIDS Care"},{"key":"706_CR25","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1071\/SH11003","volume":"8","author":"LA Cysique","year":"2011","unstructured":"Cysique LA, Bain MP, Brew BJ, Murray JM (2011) The burden of HIV-associated neurocognitive impairment in Australia and its estimates for the future. Sex Health 8:541\u2013550","journal-title":"Sex Health"},{"key":"706_CR26","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1007\/s11065-009-9092-3","volume":"19","author":"LA Cysique","year":"2009","unstructured":"Cysique LA, Brew BJ (2009) Neuropsychological functioning and antiretroviral treatment in HIV\/AIDS: a review. Neuropsychol Rev 19:169\u2013185","journal-title":"Neuropsychol Rev"},{"key":"706_CR27","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1097\/COH.0000000000000078","volume":"9","author":"LA Cysique","year":"2014","unstructured":"Cysique LA, Brew BJ (2014) The effects of HIV and aging on brain functions: proposing a research framework and update on last 3 years\u2019 findings. Curr Opin HIV AIDS 9:355\u2013364","journal-title":"Curr Opin HIV AIDS"},{"key":"706_CR28","first-page":"258","volume":"20","author":"LA Cysique","year":"2014","unstructured":"Cysique LA, Heaton RK, Kamminga J, Lane T, Gates TM, Moore DM, Hubner E, Carr A, Brew BJ (2014) HIV-associated neurocognitive disorder in Australia: a case of a high-functioning and optimally treated cohort and implications for international neuroHIV research. J Neuro-Oncol 20:258\u2013268","journal-title":"J Neuro-Oncol"},{"key":"706_CR29","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0061738","volume":"8","author":"LA Cysique","year":"2013","unstructured":"Cysique LA, Moffat K, Moore DM, Lane TA, Davies NW, Carr A, Brew BJ, Rae C (2013) HIV, vascular and aging injuries in the brain of clinically stable HIV-infected adults: a (1)H MRS study. PLoS One 8:e61738","journal-title":"PLoS One"},{"key":"706_CR30","first-page":"539","volume":"23","author":"LA Cysique","year":"2017","unstructured":"Cysique LA, Soares JR, Geng G, Scarpetta M, Moffat K, Green M, Brew BJ, Henry RG, Rae C (2017) White matter measures are near normal in controlled HIV infection except in those with cognitive impairment and longer HIV duration. J Neuro-Oncol 23:539\u2013547","journal-title":"J Neuro-Oncol"},{"key":"706_CR31","doi-asserted-by":"publisher","first-page":"2251","DOI":"10.1097\/QAD.0000000000000400","volume":"28","author":"V Dahl","year":"2014","unstructured":"Dahl V, Peterson J, Fuchs D, Gisslen M, Palmer S, Price RW (2014) Low levels of HIV-1 RNA detected in the cerebrospinal fluid after up to 10 years of suppressive therapy are associated with local immune activation. AIDS 28:2251\u20132258","journal-title":"AIDS"},{"key":"706_CR32","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1186\/s12879-018-3083-z","volume":"18","author":"H Dawood","year":"2018","unstructured":"Dawood H, Hassan-Moosa R, Zuma NY, Naidoo K (2018) Mortality and treatment response amongst HIV-infected patients 50 years and older accessing antiretroviral services in South Africa. BMC Infect Dis 18:168","journal-title":"BMC Infect Dis"},{"key":"706_CR33","doi-asserted-by":"publisher","first-page":"2178","DOI":"10.1161\/CIRCULATIONAHA.116.021978","volume":"135","author":"A Roos de","year":"2017","unstructured":"de Roos A, van der Grond J, Mitchell G, Westenberg J (2017) Magnetic resonance imaging of cardiovascular function and the brain: is dementia a cardiovascular-driven disease? Circulation 135:2178\u20132195","journal-title":"Circulation"},{"key":"706_CR34","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1002\/gps.4245","volume":"30","author":"K Deckers","year":"2015","unstructured":"Deckers K, van Boxtel MP, Schiepers OJ, de Vugt M, Munoz Sanchez JL, Anstey KJ, Brayne C, Dartigues JF, Engedal K, Kivipelto M, Ritchie K, Starr JM, Yaffe K, Irving K, Verhey FR, Kohler S (2015) Target risk factors for dementia prevention: a systematic review and Delphi consensus study on the evidence from observational studies. Int J Geriatr Psychiatry 30:234\u2013246","journal-title":"Int J Geriatr Psychiatry"},{"key":"706_CR35","doi-asserted-by":"publisher","first-page":"e34","DOI":"10.1016\/j.jstrokecerebrovasdis.2012.03.014","volume":"22","author":"M Durand","year":"2013","unstructured":"Durand M, Sheehy O, Baril JG, LeLorier J, Tremblay CL (2013) Risk of spontaneous intracranial hemorrhage in HIV-infected individuals: a population-based cohort study. J Stroke Cerebrovasc Dis 22:e34\u2013e41","journal-title":"J Stroke Cerebrovasc Dis"},{"key":"706_CR36","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0194735","volume":"13","author":"E Ford","year":"2018","unstructured":"Ford E, Greenslade N, Paudyal P, Bremner S, Smith HE, Banerjee S, Sadhwani S, Rooney P, Oliver S, Cassell J (2018) Predicting dementia from primary care records: a systematic review and meta-analysis. PLoS One 13:e0194735","journal-title":"PLoS One"},{"key":"706_CR37","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1097\/HJR.0b013e328336a150","volume":"17","author":"N Friis-Moller","year":"2010","unstructured":"Friis-Moller N, Thiebaut R, Reiss P, Weber R, Monforte AD, De Wit S, El-Sadr W, Fontas E, Worm S, Kirk O, Phillips A, Sabin CA, Lundgren JD, Law MG (2010) Predicting the risk of cardiovascular disease in HIV-infected patients: the data collection on adverse effects of anti-HIV drugs study. Eur J Cardiovasc Prev Rehabil 17:491\u2013501","journal-title":"Eur J Cardiovasc Prev Rehabil"},{"key":"706_CR38","doi-asserted-by":"publisher","first-page":"224","DOI":"10.3389\/fnagi.2018.00224","volume":"10","author":"T Fulop","year":"2018","unstructured":"Fulop T, Witkowski JM, Bourgade K, Khalil A, Zerif E, Larbi A, Hirokawa K, Pawelec G, Bocti C, Lacombe G, Dupuis G, Frost EH (2018) Can an infection hypothesis explain the beta amyloid hypothesis of Alzheimer\u2019s disease? Front Aging Neurosci 10:224","journal-title":"Front Aging Neurosci"},{"key":"706_CR39","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1007\/s40263-015-0302-7","volume":"30","author":"TM Gates","year":"2016","unstructured":"Gates TM, Cysique LA (2016) The chronicity of HIV infection should drive the research strategy of NeuroHIV treatment studies: a critical review. CNS Drugs 30:53\u201369","journal-title":"CNS Drugs"},{"key":"706_CR40","doi-asserted-by":"publisher","first-page":"e361","DOI":"10.1016\/S2352-3018(16)30087-X","volume":"3","author":"GBD 2015 HIV Collaborators","year":"2016","unstructured":"GBD 2015 HIV Collaborators (2016) Estimates of global, regional, and national incidence, prevalence, and mortality of HIV, 1980-2015: the Global Burden of Disease Study 2015. Lancet HIV 3:e361\u2013e387","journal-title":"Lancet HIV"},{"key":"706_CR41","doi-asserted-by":"publisher","first-page":"272","DOI":"10.1007\/s11904-015-0266-8","volume":"12","author":"BB Gelman","year":"2015","unstructured":"Gelman BB (2015) Neuropathology of HAND with suppressive antiretroviral therapy: encephalitis and neurodegeneration reconsidered. Curr HIV\/AIDS Rep 12:272\u2013279","journal-title":"Curr HIV\/AIDS Rep"},{"key":"706_CR42","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0046178","volume":"7","author":"BB Gelman","year":"2012","unstructured":"Gelman BB, Chen T, Lisinicchia JG, Soukup VM, Carmical JR, Starkey JM, Masliah E, Commins DL, Brandt D, Grant I, Singer EJ, Levine AJ, Miller J, Winkler JM, Fox HS, Luxon BA, Morgello S (2012) The National NeuroAIDS Tissue Consortium brain gene array: two types of HIV-associated neurocognitive impairment. PLoS One 7:e46178","journal-title":"PLoS One"},{"key":"706_CR43","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/j.jcv.2017.08.016","volume":"96","author":"M Giuliano","year":"2017","unstructured":"Giuliano M, Pirillo MF, Liotta G, Andreotti M, Jere H, Sagno JB, Ciccacci F, Amici R, Marazzi MC, Vella S, Palombi L, Mancinelli S (2017) High CMV IgG antibody levels are associated to a lower CD4+ RESPONSE to antiretroviral therapy in HIV-infected women. J Clin Virol 96:17\u201319","journal-title":"J Clin Virol"},{"key":"706_CR44","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1002\/ana.410380510","volume":"38","author":"JD Glass","year":"1995","unstructured":"Glass JD, Fedor H, Wesselingh SL, McArthur JC (1995) Immunocytochemical quantitation of human immunodeficiency virus in the brain: correlations with dementia. Ann Neurol 38:755\u2013762","journal-title":"Ann Neurol"},{"key":"706_CR45","doi-asserted-by":"publisher","first-page":"e411","DOI":"10.1016\/S2352-3018(17)30098-X","volume":"4","author":"K Goodkin","year":"2017","unstructured":"Goodkin K, Miller EN, Cox C, Reynolds S, Becker JT, Martin E, Selnes OA, Ostrow DG, Sacktor NC (2017) Effect of ageing on neurocognitive function by stage of HIV infection: evidence from the Multicenter AIDS Cohort Study. Lancet HIV 4:e411\u2013e422","journal-title":"Lancet HIV"},{"key":"706_CR46","doi-asserted-by":"publisher","first-page":"2672","DOI":"10.1161\/STR.0b013e3182299496","volume":"42","author":"PB Gorelick","year":"2011","unstructured":"Gorelick PB, Scuteri A, Black SE, Decarli C, Greenberg SM, Iadecola C, Launer LJ, Laurent S, Lopez OL, Nyenhuis D, Petersen RC, Schneider JA, Tzourio C, Arnett DK, Bennett DA, Chui HC, Higashida RT, Lindquist R, Nilsson PM, Roman GC, Sellke FW, Seshadri S (2011) Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the American Heart Association\/American Stroke Association. Stroke 42:2672\u20132713","journal-title":"Stroke"},{"key":"706_CR47","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0171887","volume":"12","author":"C Gott","year":"2017","unstructured":"Gott C, Gates T, Dermody N, Brew BJ, Cysique LA (2017) Cognitive change trajectories in virally suppressed HIV-infected individuals indicate high prevalence of disease activity. PLoS One 12:e0171887","journal-title":"PLoS One"},{"key":"706_CR48","doi-asserted-by":"publisher","first-page":"2055","DOI":"10.1212\/WNL.0000000000000492","volume":"82","author":"I Grant","year":"2014","unstructured":"Grant I, Franklin DR Jr, Deutsch R, Woods SP, Vaida F, Ellis RJ, Letendre SL, Marcotte TD, Atkinson JH, Collier AC, Marra CM, Clifford DB, Gelman BB, McArthur JC, Morgello S, Simpson DM, McCutchan JA, Abramson I, Gamst A, Fennema-Notestine C, Smith DM, Heaton RK (2014) Asymptomatic HIV-associated neurocognitive impairment increases risk for symptomatic decline. Neurology 82:2055\u20132062","journal-title":"Neurology"},{"key":"706_CR49","doi-asserted-by":"publisher","first-page":"1120","DOI":"10.1093\/cid\/cir627","volume":"53","author":"G Guaraldi","year":"2011","unstructured":"Guaraldi G, Orlando G, Zona S, Menozzi M, Carli F, Garlassi E, Berti A, Rossi E, Roverato A, Palella F (2011) Premature age-related comorbidities among HIV-infected persons compared with the general population. Clin Infect Dis 53:1120\u20131126","journal-title":"Clin Infect Dis"},{"issue":"Suppl 2","key":"706_CR50","doi-asserted-by":"publisher","first-page":"S129","DOI":"10.1097\/QAD.0000000000001478","volume":"31","author":"G Guaraldi","year":"2017","unstructured":"Guaraldi G, Palella FJ Jr (2017) Clinical implications of aging with HIV infection: perspectives and the future medical care agenda. Aids 31(Suppl 2):S129\u2013S135","journal-title":"Aids"},{"key":"706_CR51","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0176686","volume":"12","author":"J Gutierrez","year":"2017","unstructured":"Gutierrez J, Albuquerque ALA, Falzon L (2017) HIV infection as vascular risk: a systematic review of the literature and meta-analysis. PLoS One 12:e0176686","journal-title":"PLoS One"},{"key":"706_CR52","unstructured":"Gutierrez J, Byrd D, Yin MT, Morgello S (2018) Relationship between brain arterial pathology and neurocognitive performance among individuals with human immunodeficiency virus. Clin Infect Dis 11"},{"key":"706_CR53","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1186\/s12889-016-2806-6","volume":"16","author":"R Gyaneshwar","year":"2016","unstructured":"Gyaneshwar R, Naidu S, Raban MZ, Naidu S, Linhart C, Morrell S, Tukana I, Taylor R (2016) Absolute cardiovascular risk in a Fiji medical zone. BMC Public Health 16:128","journal-title":"BMC Public Health"},{"key":"706_CR54","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1097\/QAD.0b013e3283427da7","volume":"25","author":"J Harezlak","year":"2011","unstructured":"Harezlak J, Buchthal S, Taylor M, Schifitto G, Zhong J, Daar E, Alger J, Singer E, Campbell T, Yiannoutsos C, Cohen R, Navia B (2011) Persistence of HIV-associated cognitive impairment, inflammation, and neuronal injury in era of highly active antiretroviral treatment. Aids 25:625\u2013633","journal-title":"Aids"},{"key":"706_CR55","doi-asserted-by":"publisher","first-page":"594","DOI":"10.1097\/COH.0000000000000417","volume":"12","author":"CI Hatleberg","year":"2017","unstructured":"Hatleberg CI, Lundgren JD, Ryom L (2017) Are we successfully managing cardiovascular disease in people living with HIV? Curr Opin HIV AIDS 12:594\u2013603","journal-title":"Curr Opin HIV AIDS"},{"key":"706_CR56","doi-asserted-by":"publisher","first-page":"2087","DOI":"10.1212\/WNL.0b013e318200d727","volume":"75","author":"RK Heaton","year":"2010","unstructured":"Heaton RK, Clifford DB, Franklin DR Jr, Woods SP, Ake C, Vaida F, Ellis RJ, Letendre SL, Marcotte TD, Atkinson JH, Rivera-Mindt M, Vigil OR, Taylor MJ, Collier AC, Marra CM, Gelman BB, McArthur JC, Morgello S, Simpson DM, McCutchan JA, Abramson I, Gamst A, Fennema-Notestine C, Jernigan TL, Wong J, Grant I (2010) HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy: CHARTER study. Neurology 75:2087\u20132096","journal-title":"Neurology"},{"key":"706_CR57","doi-asserted-by":"publisher","first-page":"975","DOI":"10.1016\/j.bbadis.2015.12.009","volume":"1862","author":"AM Helman","year":"2016","unstructured":"Helman AM, Murphy MP (2016) Vascular cognitive impairment: modeling a critical neurologic disease in vitro and in vivo. Biochim Biophys Acta 1862:975\u2013982","journal-title":"Biochim Biophys Acta"},{"key":"706_CR58","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1097\/COH.0000000000000420","volume":"12","author":"CJ Holloway","year":"2017","unstructured":"Holloway CJ, Boccara F (2017) HIV-related cardiovascular disease: closing the gap in mortality. Curr Opin HIV AIDS 12:509\u2013512","journal-title":"Curr Opin HIV AIDS"},{"key":"706_CR59","doi-asserted-by":"publisher","first-page":"851","DOI":"10.1042\/CS20171620","volume":"132","author":"K Horsburgh","year":"2018","unstructured":"Horsburgh K, Wardlaw JM, van Agtmael T, Allan SM, Ashford MLJ, Bath PM, Brown R, Berwick J, Cader MZ, Carare RO, Davis JB, Duncombe J, Farr TD, Fowler JH, Goense J, Granata A, Hall CN, Hainsworth AH, Harvey A, Hawkes CA, Joutel A, Kalaria RN, Kehoe PG, Lawrence CB, Lockhart A, Love S, Macleod MR, Macrae IM, Markus HS, McCabe C, McColl BW, Meakin PJ, Miller A, Nedergaard M, O'Sullivan M, Quinn TJ, Rajani R, Saksida LM, Smith C, Smith KJ, Touyz RM, Trueman RC, Wang T, Williams A, Williams SCR, Work LM (2018) Small vessels, dementia and chronic diseases\u2014molecular mechanisms and pathophysiology. Clin Sci (Lond) 132:851\u2013868","journal-title":"Clin Sci (Lond)"},{"issue":"Suppl 3","key":"706_CR60","doi-asserted-by":"publisher","first-page":"S375","DOI":"10.1093\/infdis\/jis200","volume":"205","author":"PY Hsue","year":"2012","unstructured":"Hsue PY, Deeks SG, Hunt PW (2012) Immunologic basis of cardiovascular disease in HIV-infected adults. J Infect Dis 205(Suppl 3):S375\u2013S382","journal-title":"J Infect Dis"},{"key":"706_CR61","doi-asserted-by":"publisher","first-page":"534","DOI":"10.1097\/COH.0000000000000409","volume":"12","author":"PY Hsue","year":"2017","unstructured":"Hsue PY, Waters DD (2017) Heart failure in persons living with HIV infection. Curr Opin HIV AIDS 12:534\u2013539","journal-title":"Curr Opin HIV AIDS"},{"key":"706_CR62","doi-asserted-by":"publisher","first-page":"954","DOI":"10.1186\/s12889-017-4940-1","volume":"17","author":"EP Hyle","year":"2017","unstructured":"Hyle EP, Mayosi BM, Middelkoop K, Mosepele M, Martey EB, Walensky RP, Bekker LG, Triant VA (2017) The association between HIV and atherosclerotic cardiovascular disease in sub-Saharan Africa: a systematic review. BMC Public Health 17:954","journal-title":"BMC Public Health"},{"key":"706_CR63","first-page":"1","volume":"26","author":"M Johnson Shen","year":"2018","unstructured":"Johnson Shen M, Freeman R, Karpiak S, Brennan-Ing M, Seidel L, Siegler EL (2018) The intersectionality of stigmas among key populations of older adults affected by HIV: a thematic analysis. Clin Gerontol 26:1\u201313","journal-title":"Clin Gerontol"},{"key":"706_CR64","first-page":"018","volume":"12","author":"AR Kallianpur","year":"2018","unstructured":"Kallianpur AR, Gittleman H, Letendre S, Ellis R, Barnholtz-Sloan JS, Bush WS, Heaton R, Samuels DC, Franklin DR Jr, Rosario-Cookson D, Clifford DB, Collier AC, Gelman B, Marra CM, McArthur JC, McCutchan JA, Morgello S, Grant I, Simpson D, Connor JR, Hulgan T (2018) Cerebrospinal fluid ceruloplasmin, haptoglobin, and vascular endothelial growth factor are associated with neurocognitive impairment in adults with HIV infection. Mol Neurobiol 12:018\u20131329","journal-title":"Mol Neurobiol"},{"key":"706_CR65","doi-asserted-by":"publisher","first-page":"1145","DOI":"10.12659\/AJCR.905297","volume":"18","author":"LK Kouassi","year":"2017","unstructured":"Kouassi LK, Doumbia-Ouattara M (2017) Acute onset vascular dementia with bi-thalamic infarct in an HIV-positive subject. Am J Case Rep 18:1145\u20131147","journal-title":"Am J Case Rep"},{"key":"706_CR66","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1007\/s11883-017-0651-4","volume":"19","author":"JCA Lacson","year":"2017","unstructured":"Lacson JCA, Barnes RP, Bahrami H (2017) Coronary artery disease in HIV-infected patients: downside of living longer. Curr Atheroscler Rep 19:18","journal-title":"Curr Atheroscler Rep"},{"issue":"Suppl 2","key":"706_CR67","doi-asserted-by":"publisher","first-page":"S105","DOI":"10.1097\/QAD.0000000000001441","volume":"31","author":"C Lagathu","year":"2017","unstructured":"Lagathu C, Cossarizza A, Bereziat V, Nasi M, Capeau J, Pinti M (2017) Basic science and pathogenesis of ageing with HIV: potential mechanisms and biomarkers. Aids 31(Suppl 2):S105\u2013S119","journal-title":"Aids"},{"key":"706_CR68","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1055\/s-0036-1585454","volume":"36","author":"LT Le","year":"2016","unstructured":"Le LT, Spudich SS (2016) HIV-associated neurologic disorders and central nervous system opportunistic infections in HIV. Semin Neurol 36:373\u2013381","journal-title":"Semin Neurol"},{"issue":"5","key":"706_CR69","doi-asserted-by":"publisher","first-page":"770","DOI":"10.1093\/cid\/ciy170","volume":"67","author":"Scott Letendre","year":"2018","unstructured":"Letendre S, Bharti A, Perez-Valero I, Hanson B, Franklin D, Woods SP, Gianella S, de Oliveira MF, Heaton RK, Grant I, Landay AL, Lurain N (2018). Higher anti-cytomegalovirus immunoglobulin G concentrations are associated with worse neurocognitive performance during suppressive antiretroviral therapy. Clin Infect Dis 67:770\u2013777","journal-title":"Clinical Infectious Diseases"},{"key":"706_CR70","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1002261","volume":"14","author":"DM Lipnicki","year":"2017","unstructured":"Lipnicki DM, Crawford JD, Dutta R, Thalamuthu A, Kochan NA, Andrews G, Lima-Costa MF, Castro-Costa E, Brayne C, Matthews FE, Stephan BC, Lipton RB, Katz MJ, Ritchie K, Scali J, Ancelin ML, Scarmeas N, Yannakoulia M, Dardiotis E, Lam LC, Wong CH, Fung AW, Guaita A, Vaccaro R, Davin A, Kim KW, Han JW, Kim TH, Anstey KJ, Cherbuin N, Butterworth P, Scazufca M, Kumagai S, Chen S, Narazaki K, Ng TP, Gao Q, Reppermund S, Brodaty H, Lobo A, Lopez-Anton R, Santabarbara J, Sachdev PS (2017) Age-related cognitive decline and associations with sex, education and apolipoprotein E genotype across ethnocultural groups and geographic regions: a collaborative cohort study. PLoS Med 14:e1002261","journal-title":"PLoS Med"},{"key":"706_CR71","doi-asserted-by":"publisher","first-page":"378","DOI":"10.1093\/aje\/kwv451","volume":"184","author":"ER Mayeda","year":"2016","unstructured":"Mayeda ER, Tchetgen Tchetgen EJ, Power MC, Weuve J, Jacqmin-Gadda H, Marden JR, Vittinghoff E, Keiding N, Glymour MM (2016) A simulation platform for quantifying survival bias: an application to research on determinants of cognitive decline. Am J Epidemiol 184:378\u2013387","journal-title":"Am J Epidemiol"},{"key":"706_CR72","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1097\/COH.0000000000000415","volume":"12","author":"AW McCrary","year":"2017","unstructured":"McCrary AW, Nduka CU, Stranges S, Bloomfield GS (2017) Features of cardiovascular disease in low-income and middle-income countries in adults and children living with HIV. Curr Opin HIV AIDS 12:579\u2013584","journal-title":"Curr Opin HIV AIDS"},{"key":"706_CR73","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1097\/EDE.0000000000000675","volume":"28","author":"CA McHutchison","year":"2017","unstructured":"McHutchison CA, Backhouse EV, Cvoro V, Shenkin SD, Wardlaw JM (2017) Education, socioeconomic status, and intelligence in childhood and stroke risk in later life: a meta-analysis. Epidemiology 28:608\u2013618","journal-title":"Epidemiology"},{"key":"706_CR74","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1007\/s11904-017-0361-0","volume":"14","author":"B Milanini","year":"2017","unstructured":"Milanini B, Valcour V (2017) Differentiating HIV-associated neurocognitive disorders from Alzheimer\u2019s disease: an emerging issue in geriatric NeuroHIV. Curr HIV\/AIDS Rep 14:123\u2013132","journal-title":"Curr HIV\/AIDS Rep"},{"key":"706_CR75","doi-asserted-by":"publisher","first-page":"1762","DOI":"10.1093\/cid\/cix1075","volume":"66","author":"A Moulignier","year":"2018","unstructured":"Moulignier A, Savatovsky J, Assoumou L, Lescure FX, Lamirel C, Godin O, Valin N, Tubiana R, Canestri A, Roux P, Sadik JC, Salomon L, Abrivard M, Katlama C, Yazdanpanah Y, Pialoux G, Girard PM, Costagliola D (2018) Silent cerebral small-vessel disease is twice as prevalent in middle-aged individuals with well-controlled, combination antiretroviral therapy-treated human immunodeficiency virus (HIV) than in HIV-uninfected individuals. Clin Infect Dis 66:1762\u20131769","journal-title":"Clin Infect Dis"},{"key":"706_CR76","doi-asserted-by":"publisher","first-page":"1432","DOI":"10.1021\/acschemneuro.7b00169","volume":"8","author":"MT Nedelcovych","year":"2017","unstructured":"Nedelcovych MT, Manning AA, Semenova S, Gamaldo C, Haughey NJ, Slusher BS (2017) The psychiatric impact of HIV. ACS Chem Neurosci 8:1432\u20131434","journal-title":"ACS Chem Neurosci"},{"issue":"1","key":"706_CR77","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1097\/QAD.0000000000002042","volume":"33","author":"Madeleine J. Nichols","year":"2019","unstructured":"Nichols MJ, Gates TM, Soares JR, Moffat KJ, Rae CD, Brew BJ, Cysique LA (2018) Atrophic brain signatures of mild forms of neurocognitive impairment in virally suppressed HIV infection. AIDS. https:\/\/doi.org\/10.1097\/QAD.0000000000002042","journal-title":"AIDS"},{"issue":"Suppl 2","key":"706_CR78","doi-asserted-by":"publisher","first-page":"S31","DOI":"10.3233\/JAD-2012-111496","volume":"30","author":"F Panza","year":"2012","unstructured":"Panza F, Solfrizzi V, Logroscino G, Maggi S, Santamato A, Seripa D, Pilotto A (2012) Current epidemiological approaches to the metabolic-cognitive syndrome. J Alzheimers Dis 30(Suppl 2):S31\u2013S75","journal-title":"J Alzheimers Dis"},{"key":"706_CR79","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1016\/j.hlc.2015.10.019","volume":"25","author":"ED Paratz","year":"2016","unstructured":"Paratz ED, Cunningham NJ, MacIsaac AI (2016) The cardiac complications of methamphetamines. Heart Lung Circ 25:325\u2013332","journal-title":"Heart Lung Circ"},{"key":"706_CR80","doi-asserted-by":"publisher","first-page":"3198","DOI":"10.1007\/s10461-018-2128-z","volume":"22","author":"S Patel","year":"2018","unstructured":"Patel S, Parikh NU, Aalinkeel R, Reynolds JL, Dmello R, Schwartz SA, Mahajan SD (2018) United States National Trends in mortality, length of stay (LOS) and associated costs of cognitive impairment in HIV population from 2005 to 2014. AIDS Behav 22:3198\u20133208","journal-title":"AIDS Behav"},{"key":"706_CR81","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1016\/j.neuroimage.2018.03.033","volume":"174","author":"SL Peng","year":"2018","unstructured":"Peng SL, Chen X, Li Y, Rodrigue KM, Park DC, Lu H (2018) Age-related changes in cerebrovascular reactivity and their relationship to cognition: a four-year longitudinal study. Neuroimage 174:257\u2013262","journal-title":"Neuroimage"},{"key":"706_CR82","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1111\/hiv.12162","volume":"15","author":"K Petoumenos","year":"2014","unstructured":"Petoumenos K, Reiss P, Ryom L, Rickenbach M, Sabin CA, El-Sadr W, d'Arminio Monforte A, Phillips AN, De Wit S, Kirk O, Dabis F, Pradier C, Lundgren JD, Law MG (2014) Increased risk of cardiovascular disease (CVD) with age in HIV-positive men: a comparison of the D:A:D CVD risk equation and general population CVD risk equations. HIV Med 15:595\u2013603","journal-title":"HIV Med"},{"key":"706_CR83","doi-asserted-by":"publisher","first-page":"844","DOI":"10.1016\/j.bpsc.2018.06.006","volume":"3","author":"A Pfefferbaum","year":"2018","unstructured":"Pfefferbaum A, Zahr NM, Sassoon SA, Kwon D, Pohl KM, Sullivan EV (2018) Accelerated and premature aging characterizing regional cortical volume loss in human immunodeficiency virus infection: contributions from alcohol, substance use, and hepatitis C coinfection. Biol Psychiatry Cogn Neurosci Neuroimaging 3:844\u2013859","journal-title":"Biol Psychiatry Cogn Neurosci Neuroimaging"},{"key":"706_CR84","doi-asserted-by":"publisher","first-page":"1393","DOI":"10.1097\/QAD.0000000000001475","volume":"31","author":"R Rajasuriar","year":"2017","unstructured":"Rajasuriar R, Chong ML, Ahmad Bashah NS, Abdul Aziz SA, McStea M, Lee ECY, Wong PL, Azwa I, Syed Omar SF, Lai PSM, Ponampalavanar S, Crowe SM, Lewin SR, Kamaruzzaman SB, Kamarulzaman A (2017) Major health impact of accelerated aging in young HIV-infected individuals on antiretroviral therapy. Aids 31:1393\u20131403","journal-title":"Aids"},{"key":"706_CR85","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1097\/COH.0000000000000407","volume":"12","author":"S Raposeiras-Roubin","year":"2017","unstructured":"Raposeiras-Roubin S, Abu-Assi E, Iniguez-Romo A (2017) Tobacco, illicit drugs use and risk of cardiovascular disease in patients living with HIV. Curr Opin HIV AIDS 12:523\u2013527","journal-title":"Curr Opin HIV AIDS"},{"key":"706_CR86","doi-asserted-by":"publisher","first-page":"1637","DOI":"10.1097\/QAD.0b013e3283493fb0","volume":"25","author":"LD Rasmussen","year":"2011","unstructured":"Rasmussen LD, Engsig FN, Christensen H, Gerstoft J, Kronborg G, Pedersen C, Obel N (2011) Risk of cerebrovascular events in persons with and without HIV: a Danish nationwide population-based cohort study. Aids 25:1637\u20131646","journal-title":"Aids"},{"key":"706_CR87","doi-asserted-by":"publisher","first-page":"e288","DOI":"10.1016\/S2352-3018(15)00077-6","volume":"2","author":"LD Rasmussen","year":"2015","unstructured":"Rasmussen LD, May MT, Kronborg G, Larsen CS, Pedersen C, Gerstoft J, Obel N (2015) Time trends for risk of severe age-related diseases in individuals with and without HIV infection in Denmark: a nationwide population-based cohort study. Lancet HIV 2:e288\u2013e298","journal-title":"Lancet HIV"},{"key":"706_CR88","doi-asserted-by":"publisher","first-page":"1594","DOI":"10.1212\/WNL.0000000000004491","volume":"89","author":"LH Rubin","year":"2017","unstructured":"Rubin LH, Maki PM, Springer G, Benning L, Anastos K, Gustafson D, Villacres MC, Jiang X, Adimora AA, Waldrop-Valverde D, Vance DE, Bolivar H, Alden C, Martin EM, Valcour VG (2017) Cognitive trajectories over 4 years among HIV-infected women with optimal viral suppression. Neurology 89:1594\u20131603","journal-title":"Neurology"},{"key":"706_CR89","doi-asserted-by":"publisher","first-page":"860","DOI":"10.1017\/S1355617717001102","volume":"23","author":"R Saloner","year":"2017","unstructured":"Saloner R, Cysique LA (2017) HIV-associated neurocognitive disorders: a global perspective. J Int Neuropsychol Soc 23:860\u2013869","journal-title":"J Int Neuropsychol Soc"},{"key":"706_CR90","doi-asserted-by":"publisher","first-page":"1787","DOI":"10.1093\/cid\/ciu701","volume":"59","author":"J Schouten","year":"2014","unstructured":"Schouten J, Wit FW, Stolte IG, Kootstra NA, van der Valk M, Geerlings SE, Prins M, Reiss P (2014) Cross-sectional comparison of the prevalence of age-associated comorbidities and their risk factors between HIV-infected and uninfected individuals: the AGEhIV cohort study. Clin Infect Dis 59:1787\u20131797","journal-title":"Clin Infect Dis"},{"key":"706_CR91","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/j.jaut.2014.08.002","volume":"54","author":"M Schwartz","year":"2014","unstructured":"Schwartz M, Baruch K (2014) Breaking peripheral immune tolerance to CNS antigens in neurodegenerative diseases: boosting autoimmunity to fight-off chronic neuroinflammation. J Autoimmun 54:8\u201314","journal-title":"J Autoimmun"},{"key":"706_CR92","doi-asserted-by":"publisher","first-page":"1933","DOI":"10.1212\/WNL.0000000000001560","volume":"84","author":"JJ Sico","year":"2015","unstructured":"Sico JJ, Chang CC, So-Armah K, Justice AC, Hylek E, Skanderson M, McGinnis K, Kuller LH, Kraemer KL, Rimland D, Bidwell Goetz M, Butt AA, Rodriguez-Barradas MC, Gibert C, Leaf D, Brown ST, Samet J, Kazis L, Bryant K, Freiberg MS (2015) HIV status and the risk of ischemic stroke among men. Neurology 84:1933\u20131940","journal-title":"Neurology"},{"key":"706_CR93","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1016\/j.jalz.2017.09.007","volume":"14","author":"OA Skrobot","year":"2018","unstructured":"Skrobot OA, Black SE, Chen C, DeCarli C, Erkinjuntti T, Ford GA, Kalaria RN, O'Brien J, Pantoni L, Pasquier F, Roman GC, Wallin A, Sachdev P, Skoog I, Ben-Shlomo Y, Passmore AP, Love S, Kehoe PG (2018) Progress toward standardized diagnosis of vascular cognitive impairment: guidelines from the Vascular Impairment of Cognition Classification Consensus Study. Alzheimers Dement 14:280\u2013292","journal-title":"Alzheimers Dement"},{"key":"706_CR94","doi-asserted-by":"publisher","first-page":"624","DOI":"10.1016\/j.jalz.2016.10.007","volume":"13","author":"OA Skrobot","year":"2017","unstructured":"Skrobot OA, O'Brien J, Black S, Chen C, DeCarli C, Erkinjuntti T, Ford GA, Kalaria RN, Pantoni L, Pasquier F, Roman GC, Wallin A, Sachdev P, Skoog I, Ben-Shlomo Y, Passmore AP, Love S, Kehoe PG (2017) The vascular impairment of cognition classification consensus study. Alzheimers Dement 13:624\u2013633","journal-title":"Alzheimers Dement"},{"key":"706_CR95","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1016\/B978-0-444-63849-6.00007-4","volume":"152","author":"RC Smail","year":"2018","unstructured":"Smail RC, Brew BJ (2018) HIV-associated neurocognitive disorder. Handb Clin Neurol 152:75\u201397","journal-title":"Handb Clin Neurol"},{"key":"706_CR96","doi-asserted-by":"publisher","first-page":"810","DOI":"10.1016\/S1473-3099(15)00056-0","volume":"15","author":"M Smit","year":"2015","unstructured":"Smit M, Brinkman K, Geerlings S, Smit C, Thyagarajan K, Sighem A, de Wolf F, Hallett TB (2015) Future challenges for clinical care of an ageing population infected with HIV: a modelling study. Lancet Infect Dis 15:810\u2013818","journal-title":"Lancet Infect Dis"},{"key":"706_CR97","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1097\/COH.0000000000000413","volume":"12","author":"L Stone","year":"2017","unstructured":"Stone L, Looby SE, Zanni MV (2017) Cardiovascular disease risk among women living with HIV in North America and Europe. Curr Opin HIV AIDS 12:585\u2013593","journal-title":"Curr Opin HIV AIDS"},{"issue":"Suppl 1","key":"706_CR98","doi-asserted-by":"publisher","first-page":"S5","DOI":"10.1097\/QAD.0000000000001322","volume":"31","author":"J Stover","year":"2017","unstructured":"Stover J, Brown T, Puckett R, Peerapatanapokin W (2017) Updates to the Spectrum\/Estimations and Projections Package model for estimating trends and current values for key HIV indicators. Aids 31(Suppl 1):S5\u2013S11","journal-title":"Aids"},{"key":"706_CR99","doi-asserted-by":"publisher","first-page":"847","DOI":"10.1097\/QAD.0000000000001414","volume":"31","author":"T Su","year":"2017","unstructured":"Su T, Mutsaerts HJ, Caan MW, Wit FW, Schouten J, Geurtsen GJ, Sharp DJ, Prins M, Richard E, Portegies P, Reiss P, Majoie CB (2017) Cerebral blood flow and cognitive function in HIV-infected men with sustained suppressed viremia on combination antiretroviral therapy. Aids 31:847\u2013856","journal-title":"Aids"},{"key":"706_CR100","doi-asserted-by":"crossref","unstructured":"Tang H, Mao Y, Tang W, Han J, Xu J, Li J (2018) Late for testing, early for antiretroviral therapy, less likely to die: results from a large HIV cohort study in China, 2006-2014. BMC Infect Dis 18:272","DOI":"10.1186\/s12879-018-3158-x"},{"key":"706_CR101","doi-asserted-by":"publisher","first-page":"859","DOI":"10.1177\/1049732318761364","volume":"28","author":"AR Terpstra","year":"2018","unstructured":"Terpstra AR, Worthington C, Ibanez-Carrasco F, O'Brien KK, Yamamoto A, Chan Carusone S, Baltzer Turje R, McDougall P, Granger W, Thompson V, DeSousa M, Creal L, Rae A, Medina C, Morley E, Rourke SB (2018) \u201cI\u2019m just forgetting and I don\u2019t know why\u201d: exploring how people living with HIV-associated neurocognitive disorder view, manage, and obtain support for their cognitive difficulties. Qual Health Res 28:859\u2013872","journal-title":"Qual Health Res"},{"key":"706_CR102","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1016\/S0140-6736(08)61113-7","volume":"372","author":"The Antiretroviral Therapy Cohort Collaboration","year":"2008","unstructured":"The Antiretroviral Therapy Cohort Collaboration (2008) Life expectancy of individuals on combination antiretroviral therapy in high-income countries: a collaborative analysis of 14 cohort studies. Lancet 372:293\u2013299","journal-title":"Lancet"},{"key":"706_CR103","doi-asserted-by":"publisher","first-page":"540","DOI":"10.1097\/COH.0000000000000410","volume":"12","author":"VA Triant","year":"2017","unstructured":"Triant VA, Grinspoon SK (2017) Epidemiology of ischemic heart disease in HIV. Curr Opin HIV AIDS 12:540\u2013547","journal-title":"Curr Opin HIV AIDS"},{"key":"706_CR104","doi-asserted-by":"publisher","first-page":"2171","DOI":"10.1097\/QAD.0000000000001950","volume":"32","author":"G Ulfhammer","year":"2018","unstructured":"Ulfhammer G, Eden A, Mellgren A, Fuchs D, Zetterberg H, Hagberg L, Nilsson S, Yilmaz A, Gisslen M (2018) Persistent central nervous system immune activation following more than 10 years of effective HIV antiretroviral treatment. Aids 32:2171\u20132178","journal-title":"Aids"},{"key":"706_CR105","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0194760","volume":"13","author":"J Underwood","year":"2018","unstructured":"Underwood J, De Francesco D, Leech R, Sabin CA, Winston A (2018) Medicalising normality? Using a simulated dataset to assess the performance of different diagnostic criteria of HIV-associated cognitive impairment. PLoS One 13:e0194760","journal-title":"PLoS One"},{"key":"706_CR106","doi-asserted-by":"publisher","first-page":"18003","DOI":"10.1038\/nrdp.2018.3","volume":"4","author":"WM Flier van der","year":"2018","unstructured":"van der Flier WM, Skoog I, Schneider JA, Pantoni L, Mok V, Chen CLH, Scheltens P (2018) Vascular cognitive impairment. Nat Rev Dis Primers 4:18003","journal-title":"Nat Rev Dis Primers"},{"key":"706_CR107","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1097\/COH.0000000000000406","volume":"12","author":"RA Zoest van","year":"2017","unstructured":"van Zoest RA, van den Born BH, Reiss P (2017) Hypertension in people living with HIV. Curr Opin HIV AIDS 12:513\u2013522","journal-title":"Curr Opin HIV AIDS"},{"key":"706_CR108","doi-asserted-by":"publisher","first-page":"1068","DOI":"10.1089\/aid.2012.0334","volume":"29","author":"MJ Vinikoor","year":"2013","unstructured":"Vinikoor MJ, Napravnik S, Floris-Moore M, Wilson S, Huang DY, Eron JJ (2013) Incidence and clinical features of cerebrovascular disease among HIV-infected adults in the Southeastern United States. AIDS Res Hum Retrovir 29:1068\u20131074","journal-title":"AIDS Res Hum Retrovir"},{"key":"706_CR109","doi-asserted-by":"publisher","first-page":"1150","DOI":"10.1212\/WNL.0b013e3181f4d5bb","volume":"75","author":"P Vivithanaporn","year":"2010","unstructured":"Vivithanaporn P, Heo G, Gamble J, Krentz HB, Hoke A, Gill MJ, Power C (2010) Neurologic disease burden in treated HIV\/AIDS predicts survival: a population-based study. Neurology 75:1150\u20131158","journal-title":"Neurology"},{"key":"706_CR110","doi-asserted-by":"publisher","first-page":"1098","DOI":"10.1016\/j.jalz.2015.06.1885","volume":"11","author":"J Weuve","year":"2015","unstructured":"Weuve J, Proust-Lima C, Power MC, Gross AL, Hofer SM, Thi\u00e9baut R, Ch\u00eane G, Glymour MM, Dufouil C (2015) Guidelines for reporting methodological challenges and evaluating potential bias in dementia research. Alzheimers Dement 11:1098\u20131109","journal-title":"Alzheimers Dement"},{"key":"706_CR111","doi-asserted-by":"publisher","first-page":"1274","DOI":"10.1016\/j.hlc.2018.03.003","volume":"27","author":"PD Wiemers","year":"2018","unstructured":"Wiemers PD, Marney L, Yadav S, Tam R, Fraser JF (2018) An overview of indigenous Australian disadvantage in terms of ischaemic heart disease. Heart Lung Circ 27:1274\u20131284","journal-title":"Heart Lung Circ"},{"key":"706_CR112","doi-asserted-by":"publisher","first-page":"208","DOI":"10.1111\/j.1468-1293.2012.01053.x","volume":"14","author":"ST Wright","year":"2013","unstructured":"Wright ST, Petoumenos K, Boyd M, Carr A, Downing S, O'Connor CC, Grotowski M, Law MG (2013) Ageing and long-term CD4 cell count trends in HIV-positive patients with 5 years or more combination antiretroviral therapy experience. HIV Med 14:208\u2013216","journal-title":"HIV Med"},{"key":"706_CR113","doi-asserted-by":"publisher","first-page":"1474","DOI":"10.1111\/acel.12802","volume":"17","author":"X Xia","year":"2018","unstructured":"Xia X, Jiang Q, McDermott J, Han JDJ (2018) Aging and Alzheimer\u2019s disease: comparison and associations from molecular to system level. Aging Cell 17:1474\u20139726","journal-title":"Aging Cell"},{"key":"706_CR114","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1186\/s12931-018-0821-0","volume":"19","author":"S Xu","year":"2018","unstructured":"Xu S, Vucic EA, Shaipanich T, Lam S, Lam W, Montaner JS, Sin DD, Paul Man SF, Leung JM (2018) Decreased telomere length in the small airway epithelium suggests accelerated aging in the lungs of persons living with human immunodeficiency virus (HIV). Respir Res 19:117","journal-title":"Respir Res"},{"key":"706_CR115","doi-asserted-by":"publisher","first-page":"3175","DOI":"10.1161\/STROKEAHA.117.016996","volume":"48","author":"JJM Zwanenburg","year":"2017","unstructured":"Zwanenburg JJM, van Osch MJP (2017) Targeting cerebral small vessel disease with MRI. Stroke 48:3175\u20133182","journal-title":"Stroke"}],"container-title":["Journal of NeuroVirology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s13365-018-0706-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s13365-018-0706-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s13365-018-0706-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,13]],"date-time":"2024-07-13T20:14:09Z","timestamp":1720901649000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s13365-018-0706-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,11]]},"references-count":115,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2019,10]]}},"alternative-id":["706"],"URL":"https:\/\/doi.org\/10.1007\/s13365-018-0706-5","relation":{},"ISSN":["1355-0284","1538-2443"],"issn-type":[{"value":"1355-0284","type":"print"},{"value":"1538-2443","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1,11]]},"assertion":[{"value":"28 October 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 November 2018","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 November 2018","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 January 2019","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"Dr. Cysique reports no conflict of interest.Prof. Brew reports personal fees from AbbVie, personal fees from ViiV, grants and personal fees from Biogen Idec, personal fees from Merck Sharpe and Dohme, and grants from National Institutes of Health, outside the submitted work.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}