{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T01:49:49Z","timestamp":1786499389885,"version":"build-2736575974"},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2019,7,11]],"date-time":"2019-07-11T00:00:00Z","timestamp":1562803200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,7,11]],"date-time":"2019-07-11T00:00:00Z","timestamp":1562803200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["PST-HN68"],"award-info":[{"award-number":["PST-HN68"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J. Neurovirol."],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1007\/s13365-019-00775-6","type":"journal-article","created":{"date-parts":[[2019,7,11]],"date-time":"2019-07-11T17:02:43Z","timestamp":1562864563000},"page":"837-843","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":37,"title":["Plasma (1\u2009\u2192\u20093)-\u03b2-d-glucan and suPAR levels correlate with neurocognitive performance in people living with HIV on antiretroviral therapy: a CHARTER analysis"],"prefix":"10.1007","volume":"25","author":[{"given":"Sara","family":"Gianella","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott L.","family":"Letendre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Iudicello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald","family":"Franklin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thaidra","family":"Gaufin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yonglong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magali","family":"Porrachia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milenka","family":"Vargas-Meneses","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald J.","family":"Ellis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malcolm","family":"Finkelman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Hoenigl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,7,11]]},"reference":[{"key":"775_CR1","doi-asserted-by":"publisher","first-page":"e2516","DOI":"10.1371\/journal.pone.0002516","volume":"3","author":"P Ancuta","year":"2008","unstructured":"Ancuta P, Kamat A, Kunstman KJ, Kim EY, Autissier P, Wurcel A, Zaman T, Stone D, Mefford M, Morgello S, Singer EJ, Wolinsky SM, Gabuzda D (2008) Microbial translocation is associated with increased monocyte activation and dementia in AIDS patients. PLoS One 3:e2516","journal-title":"PLoS One"},{"issue":"18","key":"775_CR2","doi-asserted-by":"publisher","first-page":"1789","DOI":"10.1212\/01.WNL.0000287431.88658.8b","volume":"69","author":"A Antinori","year":"2007","unstructured":"Antinori A, Arendt G, Becker JT, Brew BJ, Byrd DA, Cherner M, Clifford DB, Cinque P, Epstein LG, Goodkin K, Gisslen M, Grant I, Heaton RK, Joseph J, Marder K, Marra CM, McArthur JC, Nunn M, Price RW, Pulliam L, Robertson KR, Sacktor N, Valcour V, Wojna VE (2007) Updated research nosology for HIV-associated neurocognitive disorders. Neurology 69(18):1789\u20131799","journal-title":"Neurology"},{"issue":"6","key":"775_CR3","doi-asserted-by":"publisher","first-page":"894","DOI":"10.1080\/13854046.2012.694479","volume":"26","author":"K Blackstone","year":"2012","unstructured":"Blackstone K, Moore DJ, Franklin DR, Clifford DB, Collier AC, Marra CM, Gelman BB, McArthur JC, Morgello S, Simpson DM, Ellis RJ, Atkinson JH, Grant I, Heaton RK (2012) Defining neurocognitive impairment in HIV: deficit scores versus clinical ratings. Clin Neuropsychol 26(6):894\u2013908","journal-title":"Clin Neuropsychol"},{"key":"775_CR4","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1080\/13803390490510031","volume":"26","author":"CL Carey","year":"2004","unstructured":"Carey CL, Woods SP, Gonzalez R, Conover E, Marcotte TD, Grant I, Heaton RK, HNRC Group (2004) Predictive validity of global deficit scores in detecting neuropsychological impairment in HIV infection. J Clin Exp Neuropsychol 26:307\u2013319","journal-title":"J Clin Exp Neuropsychol"},{"issue":"5","key":"775_CR5","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1002\/ana.20076","volume":"55","author":"P Cinque","year":"2004","unstructured":"Cinque P, Nebuloni M, Santovito ML, Price RW, Gisslen M, Hagberg L, Bestetti A, Vago G, Lazzarin A, Blasi F, Sidenius N (2004) The urokinase receptor is overexpressed in the AIDS dementia complex and other neurological manifestations. Ann Neurol 55(5):687\u2013694","journal-title":"Ann Neurol"},{"issue":"4","key":"775_CR6","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1016\/j.coi.2012.05.004","volume":"24","author":"SG Deeks","year":"2012","unstructured":"Deeks SG, Verdin E, McCune JM (2012) Immunosenescence and HIV. Curr Opin Immunol 24(4):501\u2013506","journal-title":"Curr Opin Immunol"},{"key":"775_CR7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jpsychires.2015.02.021","volume":"63","author":"TG Dinan","year":"2015","unstructured":"Dinan TG, Stilling RM, Stanton C, Cryan JF (2015) Collective unconscious: how gut microbes shape human behavior. J Psychiatr Res 63:1\u20139","journal-title":"J Psychiatr Res"},{"key":"775_CR8","doi-asserted-by":"publisher","first-page":"718","DOI":"10.1111\/myc.12797","volume":"61","author":"Z Farhour","year":"2018","unstructured":"Farhour Z, Mehraj V, Chen J, Ramendra R, Lu H, Routy JP (2018) Use of (1-->3)-beta-d-glucan for diagnosis and management of invasive mycoses in HIV-infected patients. Mycoses 61:718\u2013722","journal-title":"Mycoses"},{"issue":"1","key":"775_CR9","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1017\/S1355617703910071","volume":"9","author":"R Gonzalez","year":"2003","unstructured":"Gonzalez R, Heaton RK, Moore DJ, Letendre S, Ellis RJ, Wolfson T et al (2003) Computerized reaction time battery versus a traditional neuropsychological battery: detecting HIV-related impairments. J Int Neuropsychol Soc 9(1):64\u201371","journal-title":"J Int Neuropsychol Soc"},{"issue":"23","key":"775_CR10","doi-asserted-by":"publisher","first-page":"2087","DOI":"10.1212\/WNL.0b013e318200d727","volume":"75","author":"RK Heaton","year":"2010","unstructured":"Heaton RK, Clifford DB, Franklin DR Jr, Woods SP, Ake C, Vaida F et al (2010) HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy: CHARTER study. Neurology 75(23):2087\u20132096","journal-title":"Neurology"},{"issue":"3","key":"775_CR11","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1016\/j.jinf.2018.05.001","volume":"77","author":"S Heldt","year":"2018","unstructured":"Heldt S, Prattes J, Eigl S, Spiess B, Flick H, Rabensteiner J et al (2018) Diagnosis of invasive aspergillosis in hematological malignancy patients: performance of cytokines, Asp LFD, and Aspergillus PCR in same day blood and bronchoalveolar lavage samples. J Infect 77(3):235\u2013241","journal-title":"J Infect"},{"issue":"10","key":"775_CR12","doi-asserted-by":"publisher","first-page":"1293","DOI":"10.1016\/j.cjca.2015.03.023","volume":"31","author":"GW Hodges","year":"2015","unstructured":"Hodges GW, Bang CN, Wachtell K, Eugen-Olsen J, Jeppesen JL (2015) suPAR: a new biomarker for cardiovascular disease? Can J Cardiol 31(10):1293\u20131302","journal-title":"Can J Cardiol"},{"key":"775_CR13","doi-asserted-by":"publisher","unstructured":"Hoenigl M (2019) Fungal translocation: a driving force behind the occurrence of non-AIDS events? Clin Infect Dis. \nhttps:\/\/doi.org\/10.1093\/cid\/ciz215","DOI":"10.1093\/cid\/ciz215"},{"issue":"3","key":"775_CR14","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1016\/j.clinbiochem.2012.11.004","volume":"46","author":"M Hoenigl","year":"2013","unstructured":"Hoenigl M, Raggam RB, Wagner J, Valentin T, Leitner E, Seeber K, Zollner-Schwetz I, Krammer W, Pr\u00fcller F, Grisold AJ, Krause R (2013) Diagnostic accuracy of soluble urokinase plasminogen activator receptor (suPAR) for prediction of bacteremia in patients with systemic inflammatory response syndrome. Clin Biochem 46(3):225\u2013229","journal-title":"Clin Biochem"},{"key":"775_CR15","doi-asserted-by":"crossref","unstructured":"Hoenigl M, Perez-Santiago J, Nakazawa M, Faria de Oliveira M, Zhang Y, Finkelman M et al (2016a) (1\u2009\u2192\u20093)-\u03b2-glucan: a biomarker for microbial translocation in individuals with acute or early HIV infection? Front Immunol 7:404","DOI":"10.3389\/fimmu.2016.00404"},{"issue":"11","key":"775_CR16","doi-asserted-by":"publisher","first-page":"e3162","DOI":"10.1097\/MD.0000000000003162","volume":"95","author":"Martin Hoenigl","year":"2016","unstructured":"Hoenigl M, de Oliveira MF, Perez-Santiago J, Zhang Y, Morris S, McCutchan AJ et al (2016b) (1\u2009\u2192\u20093)-beta-d-Glucan levels correlate with neurocognitive functioning in HIV-infected persons on suppressive antiretroviral therapy: a cohort study. Medicine (Baltimore) 95(11):e3162","journal-title":"Medicine"},{"issue":"4","key":"775_CR17","doi-asserted-by":"publisher","first-page":"676","DOI":"10.1093\/cid\/ciy966","volume":"69","author":"Martin Hoenigl","year":"2018","unstructured":"Hoenigl M, Moser C, Funderburg N, Bosch R, Kantor A, Zhang Y et al (2018) Soluble urokinase plasminogen activator receptor (suPAR) is predictive of non-AIDS events during antiretroviral therapy-mediated viral suppression. Clin Infect Dis. \nhttps:\/\/doi.org\/10.1093\/cid\/ciy966","journal-title":"Clinical Infectious Diseases"},{"issue":"2","key":"775_CR18","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1007\/s11904-012-0118-8","volume":"9","author":"PW Hunt","year":"2012","unstructured":"Hunt PW (2012) HIV and inflammation: mechanisms and consequences. Curr HIV\/AIDS Rep 9(2):139\u2013147","journal-title":"Curr HIV\/AIDS Rep"},{"key":"775_CR19","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1097\/QAI.0b013e318256f3bc","volume":"60","author":"A Kamat","year":"2012","unstructured":"Kamat A, Lyons JL, Misra V, Uno H, Morgello S, Singer EJ, Gabuzda D (2012) Monocyte activation markers in cerebrospinal fluid associated with impaired neurocognitive testing in advanced HIV infection. J Acquir Immune Defic Syndr 60:234\u2013243","journal-title":"J Acquir Immune Defic Syndr"},{"key":"775_CR20","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1186\/1471-2334-7-41","volume":"7","author":"SD Lawn","year":"2007","unstructured":"Lawn SD, Myer L, Bangani N, Vogt M, Wood R (2007) Plasma levels of soluble urokinase-type plasminogen activator receptor (suPAR) and early mortality risk among patients enrolling for antiretroviral treatment in South Africa. BMC Infect Dis 7:41","journal-title":"BMC Infect Dis"},{"issue":"3","key":"775_CR21","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1016\/j.chom.2013.08.006","volume":"14","author":"CA Lozupone","year":"2013","unstructured":"Lozupone CA, Li M, Campbell TB, Flores SC, Linderman D, Gebert MJ, Knight R, Fontenot AP, Palmer BE (2013) Alterations in the gut microbiota associated with HIV-1 infection. Cell Host Microbe 14(3):329\u2013339","journal-title":"Cell Host Microbe"},{"issue":"5","key":"775_CR22","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1097\/QAI.0b013e3182237e54","volume":"57","author":"JL Lyons","year":"2011","unstructured":"Lyons JL, Uno H, Ancuta P, Kamat A, Moore DJ, Singer EJ, Morgello S, Gabuzda D (2011) Plasma sCD14 is a biomarker associated with impaired neurocognitive test performance in attention and learning domains in HIV infection. J Acquir Immune Defic Syndr 57(5):371\u2013379","journal-title":"J Acquir Immune Defic Syndr"},{"key":"775_CR23","doi-asserted-by":"crossref","unstructured":"McLaurin KA, Booze RM, Mactutus CF (2019) Diagnostic and prognostic biomarkers for HAND. J Neurovirol","DOI":"10.1007\/s13365-018-0705-6"},{"key":"775_CR24","doi-asserted-by":"crossref","unstructured":"Mehraj V, Ramendra R, Isnard S, Dupuy FP, Ponte R, Chen J, Kema I, Jenabian MA, Costinuik CT, Lebouch\u00e9 B, Thomas R, Cot\u00e9 P, Leblanc R, Baril JG, Durand M, Chartrand-Lefebvre C, Tremblay C, Ancuta P, Bernard NF, Sheppard DC, Routy JP, Montreal Primary HIV Infection Study and Canadian HIV and Aging Cohort Study Groups, Milne C, Lavoie S, Friedman J, Duchastel M, Villielm F, Asselin F, Boissonnault M, Maziade PJ, Lavoie S, Milne M, Miaki NZ, Th\u00e9riault ME, Lessard B, Charron MA, Dufresne S, Turgeon ME, V\u00e9zina S, Huchet E, Kerba JP, Poliquin M, Poulin S, Rochette P, Junod P, Longpr\u00e9 D, Pilarski R, Sasseville E, Charest L, Hamel A, Cloutier-Blais A, Massoud S, Chano F, Trottier B, Labrecque L, Fortin C, Hal-Gagne V, Munoz M, Deligne B, Martel-Laferri\u00e8re V, Trottier B, Goyer ME, Teltscher M, de Pokomandy A, Cox J, Beauchamp E, Haraoui LP (2019) Circulating (1-->3)-beta-D-Glucan is associated with immune activation during HIV infection. Clin Infect Dis","DOI":"10.1093\/cid\/ciz212"},{"issue":"4","key":"775_CR25","doi-asserted-by":"publisher","first-page":"462","DOI":"10.1097\/QAI.0b013e318271799b","volume":"61","author":"A Morris","year":"2012","unstructured":"Morris A, Hillenbrand M, Finkelman M, George MP, Singh V, Kessinger C, Lucht L, Busch M, McMahon D, Weinman R, Steele C, Norris KA, Gingo MR (2012) Serum (1-->3)-beta-D-glucan levels in HIV-infected individuals are associated with immunosuppression, inflammation, and cardiopulmonary function. J Acquir Immune Defic Syndr 61(4):462\u2013468","journal-title":"J Acquir Immune Defic Syndr"},{"issue":"2","key":"775_CR26","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1086\/421944","volume":"39","author":"Z Odabasi","year":"2004","unstructured":"Odabasi Z, Mattiuzzi G, Estey E, Kantarjian H, Saeki F, Ridge RJ, Ketchum PA, Finkelman MA, Rex JH, Ostrosky-Zeichner L (2004) Beta-D-glucan as a diagnostic adjunct for invasive fungal infections: validation, cutoff development, and performance in patients with acute myelogenous leukemia and myelodysplastic syndrome. Clin Infect Dis 39(2):199\u2013205","journal-title":"Clin Infect Dis"},{"issue":"6","key":"775_CR27","doi-asserted-by":"publisher","first-page":"e001587","DOI":"10.1136\/bmjopen-2012-001587","volume":"2","author":"In\u00e9s Oliveira","year":"2012","unstructured":"Oliveira I, Andersen A, Furtado A, Medina C, da Silva D, da Silva ZJ, et al (2012) Assessment of simple risk markers for early mortality among HIV-infected patients in Guinea-Bissau: a cohort study. BMJ Open 2(6).\nhttps:\/\/doi.org\/10.1136\/bmjopen-2012-001587\n\n. Print 2012","journal-title":"BMJ Open"},{"issue":"1","key":"775_CR28","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1097\/01.qai.0000233310.90484.16","volume":"43","author":"FJ Palella Jr","year":"2006","unstructured":"Palella FJ Jr, Baker RK, Moorman AC, Chmiel JS, Wood KC, Brooks JT et al (2006) Mortality in the highly active antiretroviral therapy era: changing causes of death and disease in the HIV outpatient study. J Acquir Immune Defic Syndr 43(1):27\u201334","journal-title":"J Acquir Immune Defic Syndr"},{"issue":"12","key":"775_CR29","doi-asserted-by":"publisher","first-page":"1921","DOI":"10.1097\/QAD.0b013e3283611816","volume":"27","author":"J Perez-Santiago","year":"2013","unstructured":"Perez-Santiago J, Gianella S, Massanella M, Spina CA, Karris MY, Var SR et al (2013) Gut Lactobacillales are associated with higher CD4 and less microbial translocation during HIV infection. AIDS 27(12):1921\u20131931","journal-title":"AIDS"},{"issue":"5","key":"775_CR30","doi-asserted-by":"publisher","first-page":"984","DOI":"10.1016\/j.clinthera.2015.04.002","volume":"37","author":"AI Petra","year":"2015","unstructured":"Petra AI, Panagiotidou S, Hatziagelaki E, Stewart JM, Conti P, Theoharides TC (2015) Gut-microbiota-brain axis and its effect on neuropsychiatric disorders with suspected immune dysregulation. Clin Ther 37(5):984\u2013995","journal-title":"Clin Ther"},{"issue":"11","key":"775_CR31","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1111\/myc.12221","volume":"57","author":"J Prattes","year":"2014","unstructured":"Prattes J, Hoenigl M, Rabensteiner J, Raggam RB, Prueller F, Zollner-Schwetz I, Valentin T, H\u00f6nigl K, Fruhwald S, Krause R (2014) Serum 1,3-beta-d-glucan for antifungal treatment stratification at the intensive care unit and the influence of surgery. Mycoses 57(11):679\u2013686","journal-title":"Mycoses"},{"issue":"5","key":"775_CR32","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1093\/mmy\/myu023","volume":"52","author":"F Pruller","year":"2014","unstructured":"Pruller F, Wagner J, Raggam RB, Hoenigl M, Kessler HH, Truschnig-Wilders M, Krause R (2014) Automation of serum (1-->3)-beta-D-glucan testing allows reliable and rapid discrimination of patients with and without candidemia. Med Mycol 52(5):455\u2013461","journal-title":"Med Mycol"},{"key":"775_CR33","doi-asserted-by":"publisher","first-page":"651","DOI":"10.1111\/joim.12238","volume":"276","author":"RB Raggam","year":"2014","unstructured":"Raggam RB, Wagner J, Pruller F, Grisold A, Leitner E, Zollner-Schwetz I et al (2014) Soluble urokinase plasminogen activator receptor predicts mortality in patients with systemic inflammatory response syndrome. J Intern Med 276:651\u2013658","journal-title":"J Intern Med"},{"key":"775_CR34","doi-asserted-by":"publisher","first-page":"465","DOI":"10.3389\/fimmu.2019.00465","volume":"10","author":"R Ramendra","year":"2019","unstructured":"Ramendra R, Isnard S, Mehraj V, Chen J, Zhang Y, Finkelman M, Routy JP (2019) Circulating LPS and (1-->3)-beta-D-glucan: a Folie a Deux contributing to HIV-associated immune activation. Front Immunol 10:465","journal-title":"Front Immunol"},{"issue":"5","key":"775_CR35","doi-asserted-by":"publisher","first-page":"350","DOI":"10.1111\/hiv.12315","volume":"17","author":"LJ Rasmussen","year":"2016","unstructured":"Rasmussen LJ, Knudsen A, Katzenstein TL, Gerstoft J, Obel N, Jorgensen NR et al (2016) Soluble urokinase plasminogen activator receptor (suPAR) is a novel, independent predictive marker of myocardial infarction in HIV-1-infected patients: a nested case-control study. HIV Med 17(5):350\u2013357","journal-title":"HIV Med"},{"issue":"1","key":"775_CR36","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/j.jinf.2015.09.016","volume":"72","author":"FM Reischies","year":"2016","unstructured":"Reischies FM, Prattes J, Pruller F, Eigl S, List A, Wolfler A et al (2016) Prognostic potential of 1,3-beta-d-glucan levels in bronchoalveolar lavage fluid samples. J Infect 72(1):29\u201335","journal-title":"J Infect"},{"issue":"1\u20132","key":"775_CR37","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1016\/j.jneuroim.2004.08.038","volume":"157","author":"N Sidenius","year":"2004","unstructured":"Sidenius N, Nebuloni M, Sala S, Zerbi P, Price RW, Gisslen M, Hagberg L, Vago L, Lazzarin A, Blasi F, Cinque P (2004) Expression of the urokinase plasminogen activator and its receptor in HIV-1-associated central nervous system disease. J Neuroimmunol 157(1\u20132):133\u2013139","journal-title":"J Neuroimmunol"}],"container-title":["Journal of NeuroVirology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s13365-019-00775-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s13365-019-00775-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s13365-019-00775-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,9]],"date-time":"2020-07-09T23:24:56Z","timestamp":1594337096000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s13365-019-00775-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7,11]]},"references-count":37,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["775"],"URL":"https:\/\/doi.org\/10.1007\/s13365-019-00775-6","relation":{},"ISSN":["1355-0284","1538-2443"],"issn-type":[{"value":"1355-0284","type":"print"},{"value":"1538-2443","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,7,11]]},"assertion":[{"value":"26 December 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 May 2019","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 June 2019","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 July 2019","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The UCSD Human Research Protections Program approved the study protocol, consent, and all study-related procedures. All study participants provided voluntary, written informed consent before any study procedures were undertaken.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"MH received grant funding from Gilead. YZ and MF are employees of Associates of Cape Cod. All other authors declare no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Fungitell\u00ae, the FDA-cleared IVD kit used for the measurement of (1\u2009\u2192\u20093)-\u03b2-glucan in serum, does not have an indication for the diagnostic use of BG titers in CSF. The data presented here represents the research use only.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Off-label use"}}]}}