{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T07:12:16Z","timestamp":1791443536047,"version":"4.3.3"},"reference-count":47,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,8,29]],"date-time":"2019-08-29T00:00:00Z","timestamp":1567036800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,8,29]],"date-time":"2019-08-29T00:00:00Z","timestamp":1567036800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/100000005","name":"department of defense","doi-asserted-by":"crossref","award":["W81XWH-11-2-0174"],"award-info":[{"award-number":["W81XWH-11-2-0174"]}],"id":[{"id":"10.13039\/100000005","id-type":"DOI","asserted-by":"crossref"}]},{"name":"nih","award":["K24MH098759"],"award-info":[{"award-number":["K24MH098759"]}]},{"DOI":"10.13039\/100009054","name":"PEPFAR","doi-asserted-by":"crossref","award":["0"],"award-info":[{"award-number":["0"]}],"id":[{"id":"10.13039\/100009054","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J. Neurovirol."],"published-print":{"date-parts":[[2020,2]]},"DOI":"10.1007\/s13365-019-00794-3","type":"journal-article","created":{"date-parts":[[2019,8,29]],"date-time":"2019-08-29T16:07:48Z","timestamp":1567094868000},"page":"52-59","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Monocyte activation, HIV, and cognitive performance in East Africa"],"prefix":"10.1007","volume":"26","author":[{"given":"L. Arnoldo","family":"Mu\u00f1oz-Nev\u00e1rez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brandon M.","family":"Imp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael A.","family":"Eller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francis","family":"Kiweewa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonah","family":"Maswai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Polyak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omalla Allan","family":"Olwenyi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I. Elaine","family":"Allen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Rono","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benedetta","family":"Milanini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannah","family":"Kibuuka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie A.","family":"Ake","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leigh Anne","family":"Eller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor G.","family":"Valcour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,8,29]]},"reference":[{"issue":"5","key":"794_CR1","doi-asserted-by":"crossref","first-page":"e63804","DOI":"10.1371\/journal.pone.0063804","volume":"8","author":"ML Alcaide","year":"2013","unstructured":"Alcaide ML, Parmigiani A, Pallikkuth S, Roach M, Freguja R, Della Negra M, Bolivar H, Fischi MA, Pahwa S (2013) Immune activation in HIV- infected aging women on antiretrovirals-implications for ageassociated comorbidities: a cross-sectional pilot study. PLoS One 8(5):e63804","journal-title":"PLoS One"},{"issue":"6","key":"794_CR2","doi-asserted-by":"crossref","first-page":"e2516","DOI":"10.1371\/journal.pone.0002516","volume":"3","author":"P Anuta","year":"2008","unstructured":"Anuta P, Kamat A, Kunstman KJ, Kim EY, Autissier P, Wurcel A, Zaman T, Stone D, Mefford M, Morgello S, Singer EJ, Wolinsky SM, Gabuzda D (2008) Microbial translocation is associated with increased monocyte activation and dementia in AIDS patients. PLoS One 3(6):e2516","journal-title":"PLoS One"},{"issue":"9","key":"794_CR3","doi-asserted-by":"crossref","first-page":"e0004922","DOI":"10.1371\/journal.pntd.0004922","volume":"10","author":"SM Bartsch","year":"2016","unstructured":"Bartsch SM, Hotez PJ, Asti L, Zapf KM, Bottazzi ME, Diemert DJ, Lee BY (2016) The global economic and health burden of human hookworm infection. PLoS Negl Trop Dis 10(9):e0004922","journal-title":"PLoS Negl Trop Dis"},{"issue":"3","key":"794_CR4","doi-asserted-by":"crossref","first-page":"431","DOI":"10.4172\/2155-6113.1000431","volume":"6","author":"M Bestawros","year":"2015","unstructured":"Bestawros M, Chidumayo T, Blevins M, Canipe A, Bala J, Kelly P, Filteau S, Shepherd BE, Heimburger DC, Koethe JR (2015) Increased systemic inflammation is associated with cardiac and vascular dysfunction over the first 12 weeks of antiretroviral therapy among undernourished, HIV-infected adults in southern Africa. J AIDS Clin Res 6(3):431","journal-title":"J AIDS Clin Res"},{"issue":"12","key":"794_CR5","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1038\/nm1511","volume":"12","author":"JM Brenchley","year":"2006","unstructured":"Brenchley JM, Price DA, Schacker TW, Asher TE, Silvestri G, Rao S, Kazzaz Z, Bornstein E, Lambotte O, Altmann D, Blazar BR, Rodriguez B, Teixeira-Johnson L, Landay A, Martin JN, Hecht FM, Picker LJ, Lederman MM, Deeks SG, Douek DC (2006) Microbial translocation is a cause of systemic immune activation in chronic HIV infection. Nat Med 12(12):1365\u20131371","journal-title":"Nat Med"},{"issue":"1","key":"794_CR6","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1093\/infdis\/jir214","volume":"204","author":"TH Burdo","year":"2011","unstructured":"Burdo TH, Lentz MR, Autissier P, Krishnan A, Halpem E, Letendre S, Rosenberg ES, Ellis RJ, Williams KC et al (2011) Soluble CD163 made by monocyte\/macrophages is a novel marker of HIV activity in early and chronic infection prior to and after anti-retroviral therapy. J Infect Dis 204(1):154\u2013163","journal-title":"J Infect Dis"},{"issue":"9","key":"794_CR7","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1097\/QAD.0b013e32836010bd","volume":"27","author":"TH Burdo","year":"2013","unstructured":"Burdo TH, Weiffenbach A, Woods SP, Letendre S, Ellis RJ, Williams KC (2013) Elevated sCD163 in plasma but not cerebrospinal fluid is a marker of neurocognitive impairment in HIV infection. AIDS 27(9):1387\u20131395","journal-title":"AIDS"},{"issue":"1701","key":"794_CR8","doi-asserted-by":"crossref","first-page":"3801","DOI":"10.1098\/rspb.2010.0973","volume":"277","author":"Christopher Eppig","year":"2010","unstructured":"Eppig C, Fincher CL, Thornhill R (2010) parasite prevalence and the world- wide distribution of cognitive ability. Proc Biol Sci 277(1701):3801\u20133808","journal-title":"Proceedings of the Royal Society B: Biological Sciences"},{"issue":"26","key":"794_CR9","doi-asserted-by":"crossref","first-page":"9456","DOI":"10.1523\/JNEUROSCI.1460-11.2011","volume":"31","author":"EA Eugenin","year":"2011","unstructured":"Eugenin EA, Clements JE, Zink MC, Berman JW (2011) Human immunodeficiency virus infection of human astrocytes disrupts blood-brain barrier integrity by a gap junction-dependent mechanism. J Neurosci 31(26):9456\u20139465","journal-title":"J Neurosci"},{"issue":"2","key":"794_CR10","doi-asserted-by":"crossref","first-page":"e30","DOI":"10.4081\/jphia.2011.e30","volume":"2","author":"SM Fletcher","year":"2011","unstructured":"Fletcher SM, Stark D, Ellis J (2011) Prevalence of gastrointestinal pathogens in sub-Saharan Africa: systematic review and meta-analysis. J Public Health Africa 5 2(2):e30","journal-title":"J Public Health Africa 5"},{"issue":"1","key":"794_CR11","doi-asserted-by":"crossref","first-page":"42","DOI":"10.4081\/jphr.2013.e9","volume":"2","author":"SM Fletcher","year":"2013","unstructured":"Fletcher SM, McLaws ML, Ellis JT (2013) Prevalence of gastrointestinal pathogens in developed and developing countries: systematic review and meta-analysis. J Public Health Res 2(1):42\u201353","journal-title":"J Public Health Res"},{"issue":"5","key":"794_CR12","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/0167-5699(88)91203-0","volume":"9","author":"D Fuchs","year":"1988","unstructured":"Fuchs D, Hausen A, Reibnegger G, Werner ER, Dierich MP, Wachter H (1988) Neopterin as a marker for activated cell-mediated immunity: application in HIV infection. Immunol Today 9(5):150\u2013155","journal-title":"Immunol Today"},{"issue":"5","key":"794_CR13","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1097\/00002030-198905000-00006","volume":"3","author":"D Fuchs","year":"1989","unstructured":"Fuchs D, Chiodi F, Albert J, Asj\u00f6 B, Hagberg L, Hausen A, Norkrans G, Reibnegger G, Werner ER, Wachter H (1989) Neopterin concentrations in cerebrospinal fluid and serum of individuals infected with HIV-1. AIDS 3(5):285\u2013288","journal-title":"AIDS"},{"key":"794_CR14","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1111\/j.1749-6632.2010.05726.x","volume":"1207","author":"PB Gorelick","year":"2010","unstructured":"Gorelick PB (2010) Role of inflammation in cognitive impairment: results of observational epidemiological studies and clinical trials. Ann N Y Acad Sci 1207:155\u2013162","journal-title":"Ann N Y Acad Sci"},{"issue":"1","key":"794_CR15","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1212\/WNL.41.1.69","volume":"41","author":"DE Griffin","year":"1991","unstructured":"Griffin DE, McArthur JC, Cornblath DR (1991) Neopterin and interferon- gamma in serum and cerebrospinal fluid of patients with HIV-associated neurologic disease. Neurology 41(1):69\u201374","journal-title":"Neurology"},{"issue":"1","key":"794_CR16","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/s13365-010-0006-1","volume":"17","author":"RK Heaton","year":"2011","unstructured":"Heaton RK, Franklin DR, Ellis RJ, McCutchan JA, Letendre SL, Leblanc S, Corkran SH, Duarte NA, Clifford DB, Woods SP, Collier AC, Marra CM, Morgello S, Mindt MR, Taylor MJ, Marcotte TD, Atkinson JH, Wolfson T, Gelman BB, McArthur JC, Simpson DM, Abramson I, Gamst A, Fennema-Notestine C, Jemigan TL, Wong J, Grant I (2011) HIV-associated neurocognitive disorders before and during the era of combination antiretroviral therapy: differences in rates, nature, and predictors. J Neurovirol 17(1):3\u201316","journal-title":"J Neurovirol"},{"issue":"22","key":"794_CR17","doi-asserted-by":"crossref","first-page":"2086","DOI":"10.1056\/NEJMp1014637","volume":"364","author":"PJ Hotez","year":"2011","unstructured":"Hotez PJ, Mistry N, Rubinstein J, Sachs JD (2011) Integrating neglected tropical diseases into AIDS, tuberculosis, and malaria control. N Engl J Med 364(22):2086\u20132089","journal-title":"N Engl J Med"},{"issue":"1","key":"794_CR18","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1093\/infdis\/jiw506","volume":"215","author":"BM Imp","year":"2017","unstructured":"Imp BM, Rubin LH, Tien PC, Plankey MW, Golub ET, French AL, Valcour VG (2017) Monocyte activation is associated with worse cognitive performance in HIV-infected women with virologic suppression. J Infect Dis 215(1):114\u2013121","journal-title":"J Infect Dis"},{"issue":"8","key":"794_CR19","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1086\/597476","volume":"199","author":"W Jiang","year":"2009","unstructured":"Jiang W, Lederman MM, Hunter P, Sieg SF, Haley K, Rodriguez B, Landay A, Martin J, Sinclair E, Asher AI, Deeks SG, Douek DC, Brenchley JM (2009) Plasma levels of bacterial DNA correlate with immune activation and the magnitude of immune restoration in persons with antiretroviral-treated HIV infection. J Infect Dis 199(8):1177\u20131185","journal-title":"J Infect Dis"},{"issue":"1","key":"794_CR20","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.tim.2012.09.001","volume":"21","author":"NR Klatt","year":"2013","unstructured":"Klatt NR, Funderburg NT, Brenchley JM (2013) Microbial translocation, immune activation, and HIV disease. Trends Microbiol 21(1):6\u201313","journal-title":"Trends Microbiol"},{"key":"794_CR21","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1186\/s12986-016-0089-7","volume":"13","author":"E Lau","year":"2016","unstructured":"Lau E, Marques C, Pestana D, Santoalha M, Carvalho D, Freitas P, Calhau C (2016) The role of I-FABP as a biomarker of intestinal barrier dysfunction driven by gut microbiota changes in obesity. Nutr Metab (Lond) 13:31","journal-title":"Nutr Metab (Lond)"},{"issue":"2","key":"794_CR22","doi-asserted-by":"crossref","first-page":"e17233","DOI":"10.1371\/journal.pone.0017233","volume":"6","author":"K Lawler","year":"2011","unstructured":"Lawler K, Jeremiah K, Mosepele M, Ratcliffe SJ, Cherry C, Seloilwe E, Steenhoff AP (2011) Neurobehavioral effects in HIV-positive individuals receiving highly active antiretroviral therapy (HAART) in Gaborone, Botswana. PLoS One 6(2):e17233","journal-title":"PLoS One"},{"issue":"5","key":"794_CR23","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1097\/QAI.0b013e3182237e54","volume":"57","author":"JL Lyons","year":"2011","unstructured":"Lyons JL, Uno H, Ancuta P, Kamat A, Moore DJ, Singer EJ, Morgello S, Gabuzda D (2011) Plasma sCD14 is a biomarker associated with impaired neurocognitive test performance in attention and learning domains in HIV infection. J Acquir Immune Defic Syndr 57(5):371\u2013379","journal-title":"J Acquir Immune Defic Syndr"},{"key":"794_CR24","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1192\/bjp.159.3.351","volume":"159","author":"M Maj","year":"1991","unstructured":"Maj M, Janssen R, Satz P, Zaudig M, Starace F, Boor D, Sughondhabirom B, Bing EG, Luabeya MK, Ndetei D et al (1991) The World Health Organization\u2019s cross-cultural study on neuropsychiatric aspects of infection with the human immunodeficiency virus (HIV-1). Br J Psychiatry 159:351\u2013356","journal-title":"Br J Psychiatry"},{"issue":"2","key":"794_CR25","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.virol.2004.08.024","volume":"329","author":"G van Marle","year":"2009","unstructured":"van Marle G, Henry S, Todoruk T, Sullivan A, Silva C, Rourke SB, Holden J, McArthur JC, Gill MJ, Power C (2009) Human immunodeficiency virus type 1 Nef protein mediates neural cell death: a neurotoxic role for IP-10. Virology 329(2):302\u2013318","journal-title":"Virology"},{"key":"794_CR26","volume-title":"Instruction manual for the adult neuropsychology test battery. University of Wisconsin Medical School","author":"CG Matthews","year":"1964","unstructured":"Matthews CG, Klove J (1964) Instruction manual for the adult neuropsychology test battery. University of Wisconsin Medical School. Madison, WI"},{"issue":"17","key":"794_CR27","doi-asserted-by":"crossref","first-page":"2477","DOI":"10.1097\/QAD.0000000000001968","volume":"32","author":"B Milanini","year":"2018","unstructured":"Milanini B, Paul R, Bahemana E, Adamu Y, Kiweewa F, Langat R, Owuoth J, Allen E, Polyak C, Ake J, Valcour V (2018) Limitations of the international HIV dementia scale in the current era. AIDS 32(17):2477\u20132483","journal-title":"AIDS"},{"issue":"1","key":"794_CR28","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3109\/00365513.2011.626868","volume":"72","author":"HJ Moller","year":"2012","unstructured":"Moller HJ (2012) Soluble CD163. J Clin Lab Invest 72(1):1\u201313","journal-title":"J Clin Lab Invest"},{"issue":"13","key":"794_CR29","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1186\/1471-244X-13-126","volume":"3","author":"J Nakku","year":"2013","unstructured":"Nakku J, Kinyanda E, Hoskins S (2013) Prevalence and factors associated with probable HIV dementia in an African population: a cross-sectional study of an HIV\/AIDS clinic population. BMC Psychiatry 3(13):126","journal-title":"BMC Psychiatry"},{"issue":"4","key":"794_CR30","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1097\/QAI.0b013e318183a9df","volume":"49","author":"AK Njamnshi","year":"2008","unstructured":"Njamnshi AK, Djientcheu V, Fonsah JY, Yepnjio FN, Njamnshi DM, Muna WE (2008) The international HIV dementia scale is a useful screening tool for HIV-associated dementia\/cognitive impairment in HIV-infected adults in Yaound\u00e9-Cameroon. J Acquir Immune Defic Syndr 49(4):393\u2013397","journal-title":"J Acquir Immune Defic Syndr"},{"issue":"1","key":"794_CR31","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1097\/QAI.0000000000000915","volume":"72","author":"OA Olwenyi","year":"2015","unstructured":"Olwenyi OA, Naluyima P, Cham F, Quinn TC, Serwadda D, Sewankambo NK, Gray RH, Sandberg JK, Michael NL, Wabwire-Mangen F, Robb ML, Eller MA (2015) Brief report: differential associations of interleukin 6 and intestinal fatty acid-binding protein with progressive untreated HIV-1 infection in Rakai, Uganda. J Acquir Immune Defic Syndr 72(1):15\u201320","journal-title":"J Acquir Immune Defic Syndr"},{"issue":"3","key":"794_CR32","first-page":"104","volume":"20","author":"OO Oshinaike","year":"2010","unstructured":"Oshinaike OO, Okubadejo NU, Ojini FI, Danesi MA (2010) A preliminary study of the frequency of focal neurological deficits in HIV\/AIDS patients seropositive for toxoplasma gondii IgG in Lagos, Nigeria. Nig Q J Hosp Med 20(3):104\u2013107","journal-title":"Nig Q J Hosp Med"},{"issue":"5","key":"794_CR33","doi-asserted-by":"crossref","first-page":"1599","DOI":"10.1016\/S0002-9440(10)65476-4","volume":"155","author":"Y Persidsky","year":"1999","unstructured":"Persidsky Y, Ghorpade A, Rasmussen J, Limoges J, Liu XJ, Stins M, Fiala M, Way D, Kim KS, Witte MH, Weinand M, Carhart L, Gendelman HE (1999) Microglial and astrocyte chemokines regulate monocyte migration through the blood-brain barrier in human immunodeficiency virus-1 encephalitis. Am J Pathol 155(5):1599\u20131611","journal-title":"Am J Pathol"},{"issue":"1","key":"794_CR34","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/S1044-7431(03)00171-4","volume":"24","author":"H Pu","year":"2003","unstructured":"Pu H, Tian J, Flora G, Lee YW, Nath A, Hennig B, Toborek M (2003) HIV- 1 tat protein upregulates inflammatory mediators and induces monocyte invasion into the brain. Mol Cell Neurosci 24(1):224\u2013237","journal-title":"Mol Cell Neurosci"},{"issue":"11","key":"794_CR35","first-page":"13","volume":"19","author":"VR Rao","year":"2014","unstructured":"Rao VR, Ruiz AP, Prasad VR (2014) Viral and cellular factors underlying neuropathogenesis in HIV associated neurocognitive disorders (HAND). AIDS Res Ther 19(11):13","journal-title":"AIDS Res Ther"},{"key":"794_CR36","volume-title":"The Halstead-Reitan neuropsychological test battery: theory and clinical interpretation","author":"RM Reitan","year":"1985","unstructured":"Reitan RM, Wolfson D (1985) The Halstead-Reitan neuropsychological test battery: theory and clinical interpretation. Neuropsychology Press, Tucson"},{"issue":"3","key":"794_CR37","first-page":"189","volume":"16","author":"K Robertson","year":"2010","unstructured":"Robertson K, Liner J, Hakim J, Sankal\u00e9 JL, Grant I, Letendre S, Clifford D, Diop AG, Jaye A, Kanmogne G, Njamnshi A, Langford TD, Weyessa TG, Wood C, Banda M, Hosseinipour M, Sacktor N, Nakasuja N, Bangirana P, Paul R, Joska J, Wong J, Boivin M, Holding P, Kammerer B, Van Rie A, Ive P, Nath A, Lawler K, Adebamowo C, Royal W 3rd, Joseph J (2010) NeuroAIDS in Africa. J Neuro-Oncol 16(3):189\u2013202","journal-title":"J Neuro-Oncol"},{"issue":"2","key":"794_CR38","doi-asserted-by":"crossref","first-page":"e0147182","DOI":"10.1371\/journal.pone.0147182","volume":"11","author":"W Royal 3rd","year":"2016","unstructured":"Royal W 3rd, Cherner M, Burdo TH, Umlauf A, Letendre SL, Jumare J, Abimiku A, Alabi P, Alkali N, Bwala S, Okwuasaba K, Eyzaguirre LM, Akolo C, Guo M, Williams KC, Blattner WA (2016) Associations between cognition, gen- der and monocyte activation among HIV infected individuals in Nigeria. PLoS One 11(2):e0147182","journal-title":"PLoS One"},{"issue":"6","key":"794_CR39","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1093\/infdis\/jiq118","volume":"203","author":"NG Sandler","year":"2011","unstructured":"Sandler NG, Wand H, Roque A, Law M, Nason MC, Nixon DE, Pedersen C, Ruxrungtham K, Lewin SR, Emery S, Neaton JD, Brenchley JM, Deeks SG, Sereti I, Douek DC (2011) Plasma levels of soluble CD14 independently predict mortality in HIV infection. J Infect Dis 203(6):780\u2013790","journal-title":"J Infect Dis"},{"issue":"5","key":"794_CR40","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1093\/infdis\/jiv067","volume":"212","author":"JE Scriven","year":"2015","unstructured":"Scriven JE, Rhein J, Hullsiek KH, von Hohenberg M, Linder G, Rolfes MA, Williams DA, Taseera K, Meya DB, Meintjes G, Boulware DR (2015) Early ART after cryptococcal meningitis is associated with cerebrospinal fluid pleocytosis and macrophage activation in a multisite randomized trial. J Infect Dis 212(5):769\u2013778","journal-title":"J Infect Dis"},{"issue":"3","key":"794_CR41","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1177\/2040622311399145","volume":"2","author":"AA Simen","year":"2011","unstructured":"Simen AA, Bordner KA, Martin MP, Moy LA, Barry LC (2011) Cognitive dysfunction with aging and the role of inflammation. Ther Adv Chronic Dis 2(3):175\u2013195","journal-title":"Ther Adv Chronic Dis"},{"issue":"7","key":"794_CR42","first-page":"CD000,371","volume":"23","author":"DC Taylor-Robinson","year":"2015","unstructured":"Taylor-Robinson DC, Maayan N, Soares-Weiser K, Donegan S, Garner P (2015) Deworming drugs for soil-transmitted intestinal worms in children: effects on nutritional indicators, haemoglobin, and school performance. Cochrane Database Syst Rev 23(7):CD000,371","journal-title":"Cochrane Database Syst Rev"},{"issue":"6","key":"794_CR43","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/S1471-4906(02)02233-0","volume":"23","author":"M Triantafilou","year":"2002","unstructured":"Triantafilou M, Triantafilou K (2002) Lipopolysaccharide recognition: CD14, TLRs and the LPSactivation cluster. Trends Immunol 23(6):301\u2013304","journal-title":"Trends Immunol"},{"issue":"9","key":"794_CR44","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1046\/j.1365-3156.2002.00927.x","volume":"7","author":"JK Tumwine","year":"2002","unstructured":"Tumwine JK, Thompson J, Katua-Katua M, Mujwajuzi M, Johnstone M, Porras I (2002) Diarrhoea and effects of different water sources, sanitation and hygiene behaviour in East Africa. Tropical Med Int Health 7(9):750\u2013756","journal-title":"Tropical Med Int Health"},{"issue":"1","key":"794_CR45","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/S0014-5793(97)00674-1","volume":"411","author":"S Vesce","year":"1997","unstructured":"Vesce S, Bezzi P, Rossi D, Meldosi J, Volterra A (1997) HIV-1 gp120 glycoprotein affects the astrocyte control of extracellular glutamate by both inhibiting the uptake and stimulating the release of the amino acid. FEBS Lett 411(1):107\u2013109","journal-title":"FEBS Lett"},{"issue":"1","key":"794_CR46","doi-asserted-by":"crossref","first-page":"e40","DOI":"10.1016\/S2214-109X(16)30242-X","volume":"5","author":"VA Welch","year":"2017","unstructured":"Welch VA, Ghogomu E, Hossain A, Awasthi S, Bhutta ZA, Cumberbatch C, Fletcher R, McGowan J, Krishnaratne S, Kristjansson E, Sohani S, Suresh S, Tugwell P, White H, Wells GA et al (2017) Mass deworming to improve developmental health and wellbeing of children in low-income and middle- income countries: a systematic review and network meta-analysis. Lancet Glob Health 5(1):e40\u2013e50","journal-title":"Lancet Glob Health"},{"issue":"5","key":"794_CR47","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1212\/01.wnl.0000252811.48891.6d","volume":"68","author":"MH Wong","year":"2007","unstructured":"Wong MH, Robertson K, Nakasujja N, Skolasky R, Musisi S, Katabira E, McArthur JC, Ronald A, Sacktor N (2007) Frequency of and risk factors for HIV dementia in an HIV clinic in sub-Saharan Africa. Neurology 68(5):350\u2013355","journal-title":"Neurology"}],"container-title":["Journal of NeuroVirology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s13365-019-00794-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s13365-019-00794-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s13365-019-00794-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,27]],"date-time":"2020-08-27T23:52:06Z","timestamp":1598572326000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s13365-019-00794-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,29]]},"references-count":47,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,2]]}},"alternative-id":["794"],"URL":"https:\/\/doi.org\/10.1007\/s13365-019-00794-3","relation":{},"ISSN":["1355-0284","1538-2443"],"issn-type":[{"value":"1355-0284","type":"print"},{"value":"1538-2443","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,8,29]]},"assertion":[{"value":"4 May 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 August 2019","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 August 2019","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 August 2019","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"Dr. Valcour has served as a consultant for ViiV Healthcare, Merck, and IAS-USA on topics related to aging and HIV. All other authors have nothing to declare. The views expressed are those of the authors and should not be construed to represent the positions of the US Army or the Department of Defense.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}}]}}