{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T11:10:33Z","timestamp":1781176233081,"version":"3.54.1"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2019,12,23]],"date-time":"2019-12-23T00:00:00Z","timestamp":1577059200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,12,23]],"date-time":"2019-12-23T00:00:00Z","timestamp":1577059200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81671183"],"award-info":[{"award-number":["81671183"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J. Neurovirol."],"published-print":{"date-parts":[[2020,4]]},"DOI":"10.1007\/s13365-019-00816-0","type":"journal-article","created":{"date-parts":[[2019,12,23]],"date-time":"2019-12-23T19:02:49Z","timestamp":1577127769000},"page":"181-187","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Genome-based analysis of SFTSV causing severe encephalitis with brain lesions"],"prefix":"10.1007","volume":"26","author":[{"given":"Chunjuan","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Gong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziling","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongzhi","family":"Guan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weijun","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yifeng","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shougang","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,12,23]]},"reference":[{"key":"816_CR1","doi-asserted-by":"publisher","first-page":"324","DOI":"10.1016\/0042-6822(92)90709-X","volume":"189","author":"D Antic","year":"1992","unstructured":"Antic D, Wright KE, Kang CY (1992) Maturation of Hantaan virus glycoproteins G1 and G2. Virology 189:324\u2013328","journal-title":"Virology"},{"issue":"15","key":"816_CR2","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1016\/j.jneuroim.2017.04.008","volume":"308","author":"MD Cain","year":"2017","unstructured":"Cain MD, Salimi H, Gong Y, Yang L, Hamilton SL, Heffernan JR et al (2017) Virus entry and replication in the brain precedes blood-brain barrier disruption during intranasal alphavirus infection[J]. J neuroimmunol 308(15):118\u2013130. https:\/\/doi.org\/10.1016\/j.jneuroim.2017.04.008","journal-title":"J neuroimmunol"},{"issue":"12","key":"816_CR3","doi-asserted-by":"publisher","first-page":"e0005264","DOI":"10.1371\/journal.pntd.0005264","volume":"10","author":"SJ Choi","year":"2016","unstructured":"Choi SJ, Park SW, Bae IG, Kim SH, Ryu SY, Kim HA et al (2016) Severe fever with thrombocytopenia syndrome in South Korea, 2013-2015. PloS Negl Trop Dis 10(12):e0005264. https:\/\/doi.org\/10.1371\/journal.pntd.0005264","journal-title":"PloS Negl Trop Dis"},{"key":"816_CR4","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1016\/j.jinf.2014.08.001","volume":"70","author":"N Cui","year":"2015","unstructured":"Cui N, Liu R, Lu QB, Wang LY, Qin SL, Yang ZD, Zhuang L, Liu K, Li H, Zhang XA, Hu JG, Wang JY, Liu W, Cao WC (2015) Severe fever with thrombocytopenia syndrome bunyavirus-related human encephalitis. J Infect 70:52\u201359. https:\/\/doi.org\/10.1016\/j.jinf.2014.08.001","journal-title":"J Infect"},{"key":"816_CR5","doi-asserted-by":"publisher","first-page":"e80802","DOI":"10.1371\/journal.pone.0080802","volume":"8","author":"B Deng","year":"2013","unstructured":"Deng B, Zhou B, Zhang S, Zhu Y, Han L, Geng Y, Jin Z, Liu H, Wang D, Zhao Y, Wen Y, Cui W, Zhou Y, Gu Q, Sun C, Lu X, Wang W, Wang Y, Li C, Wang Y, Yao W, Liu P (2013) Clinical features and factors associated with severity and fatality among patients with severe fever with thrombocytopenia syndrome Bunyavirus infection in Northeast China. PloS one 8:e80802. https:\/\/doi.org\/10.1371\/journal.pone.0080802","journal-title":"PloS one"},{"key":"816_CR6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.2174\/1874279300903010001","volume":"3","author":"S Ferrari","year":"2009","unstructured":"Ferrari S, Toniolo A, Monaco S, Luciani F, Cainelli F, Baj A et al (2009) Viral encephalitis: etiology, clinical features, diagnosis and management. Open Infect Dis J 3:1\u201312","journal-title":"Open Infect Dis J"},{"issue":"5","key":"816_CR7","doi-asserted-by":"publisher","first-page":"592","DOI":"10.11150\/kansenshogakuzasshi.89.592","volume":"89","author":"Masahiko KANEKO","year":"2015","unstructured":"Kaneko M, Azuma T, Yasukawa M, Shinomiya H (2015) A fatal case of severe fever with thrombocytopenia syndrome complicated by hemophagocytic lymphohistiocytosis. J Jpn Assoc Infect Dis (Kansenshogaku Zasshi) 89:592e6. 26630792","journal-title":"Kansenshogaku Zasshi"},{"issue":"7","key":"816_CR8","doi-asserted-by":"publisher","first-page":"614","DOI":"10.1016\/j.cmi.2015.03.001","volume":"21","author":"DX Li","year":"2015","unstructured":"Li DX (2015) Severe fever with thrombocytopenia syndrome: a newly discovered emerging infectious disease. Clin Microbiol Infect. 21(7):614\u2013620. https:\/\/doi.org\/10.1016\/j.cmi.2015.03.001","journal-title":"Clin Microbiol Infect."},{"key":"816_CR9","doi-asserted-by":"publisher","first-page":"763","DOI":"10.1016\/S1473-3099(14)70718-2","volume":"14","author":"Q Liu","year":"2014","unstructured":"Liu Q, He B, Huang SY, Wei F, Zhu XQ (2014) Severe fever with thrombocytopenia syndrome, an emerging tick-borne zoonosis. Lancet Infect Dis 14:763\u2013772. https:\/\/doi.org\/10.1016\/S1473-3099(14)70718-2","journal-title":"Lancet Infect Dis"},{"key":"816_CR10","doi-asserted-by":"publisher","first-page":"3198","DOI":"10.1128\/JVI.02655-06","volume":"81","author":"AK Overby","year":"2007","unstructured":"Overby AK, Pettersson RF, Neve EP (2007) The glycoprotein cytoplasmic tail of Uukuniemi virus (Phenuiviridae) interacts with ribonucleoproteins and is critical for genome packaging. J. Virol. 81:3198\u20133205. https:\/\/doi.org\/10.1128\/JVI.02655-06","journal-title":"J. Virol."},{"issue":"8","key":"816_CR11","doi-asserted-by":"publisher","first-page":"2557","DOI":"10.3389\/fmicb.2017.02557","volume":"22","author":"MP Papa","year":"2017","unstructured":"Papa MP, Meuren LM, Coelho SVA, Lucas CGO, Mustafa YM, Lemos Matassoli F et al (2017) Zika Virus infects, activates, and crosses brain microvascular endothelial cells, without barrier disruption. Front Microbiol 22(8):2557. https:\/\/doi.org\/10.3389\/fmicb.2017.02557","journal-title":"Front Microbiol"},{"issue":"4","key":"816_CR12","doi-asserted-by":"publisher","first-page":"432","DOI":"10.1016\/j.cmi.2017.09.002","volume":"24","author":"SY Park","year":"2018","unstructured":"Park SY, Kwon JS, Kim JY, Kim SM, Jiang YR, Kim MC et al (2018) Severe fever with thrombocytopenia syndrome-associated encephalopathy\/encephalitis. Clin Microbiol Infect 24(4):432\u2013e1-432. https:\/\/doi.org\/10.1016\/j.cmi.2017.09.002","journal-title":"Clin Microbiol Infect"},{"key":"816_CR13","first-page":"159","volume-title":"The Phenuiviridae","author":"RF Pettersson","year":"1996","unstructured":"Pettersson RF, Melin L (1996) Synthesis, assembly, and intracellular transport of Phenuiviridae membrane proteins. In: Elliott R (ed) The Phenuiviridae. Plenum Press, New York, USA, pp 159\u2013183"},{"key":"816_CR14","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1016\/j.virol.2013.01.001","volume":"437","author":"T Strandin","year":"2013","unstructured":"Strandin T, Hepojoki J, Vaheri A (2013) Cytoplasmic tails of bunyavirus Gn glycoproteins-could they act as matrix protein surrogates? Virology. 437:73\u201380. https:\/\/doi.org\/10.1016\/j.virol.2013.01.001","journal-title":"Virology."},{"key":"816_CR15","first-page":"256","volume":"27","author":"YH Xie","year":"2012","unstructured":"Xie YH, Yang JY, Tan Y, Lin M, Bi FY, Wu XH et al (2012) Clinical features and evaluation of clinical diagnosis of viral encephalitis. Dis Surveill 27:256\u2013262","journal-title":"Dis Surveill"},{"issue":"11","key":"816_CR16","doi-asserted-by":"publisher","first-page":"e1002369","DOI":"10.1371\/journal.ppat.1002369","volume":"7","author":"B Xu","year":"2011","unstructured":"Xu B, Liu L, Huang X, Ma H, Zhang Y, Du Y et al (2011) Metagenomic analysis of fever, thrombocytopenia and leukopenia syndrome (FTLS) in Henan Province, China: Discovery of a New Bunyavirus. PLoS Pathog 7(11):e1002369. https:\/\/doi.org\/10.1371\/journal.ppat.1002369","journal-title":"PLoS Pathog"},{"key":"816_CR17","doi-asserted-by":"publisher","first-page":"1523","DOI":"10.1056\/NEJMoa1010095","volume":"364","author":"XJ Yu","year":"2011","unstructured":"Yu XJ, Liang MF, Zhang SY, Liu Y, Li JD, Sun YL et al (2011) Fever with thrombocytopenia associated with a novel bunyavirus in China. N Engl J Med 364:1523\u20131532. https:\/\/doi.org\/10.1056\/NEJMoa1010095","journal-title":"N Engl J Med"},{"issue":"1","key":"816_CR18","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1007\/s12250-016-3858-6","volume":"32","author":"F Yuan","year":"2017","unstructured":"Yuan F, Zheng A (2017 Feb) Entry of severe fever with thrombocytopenia syndrome virus. Virol Sin. 32(1):44\u201350. https:\/\/doi.org\/10.1007\/s12250-016-3858-6","journal-title":"Virol Sin."}],"container-title":["Journal of NeuroVirology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13365-019-00816-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s13365-019-00816-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13365-019-00816-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,29]],"date-time":"2022-07-29T12:54:08Z","timestamp":1659099248000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s13365-019-00816-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12,23]]},"references-count":18,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,4]]}},"alternative-id":["816"],"URL":"https:\/\/doi.org\/10.1007\/s13365-019-00816-0","relation":{},"ISSN":["1355-0284","1538-2443"],"issn-type":[{"value":"1355-0284","type":"print"},{"value":"1538-2443","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,12,23]]},"assertion":[{"value":"19 June 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 October 2019","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 November 2019","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 December 2019","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}