{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T11:34:44Z","timestamp":1770291284529,"version":"3.49.0"},"reference-count":53,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2021,4,19]],"date-time":"2021-04-19T00:00:00Z","timestamp":1618790400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2021,4,19]],"date-time":"2021-04-19T00:00:00Z","timestamp":1618790400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 NS086890"],"award-info":[{"award-number":["R01 NS086890"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["DP1 DA041722"],"award-info":[{"award-number":["DP1 DA041722"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["RF1 AG057409"],"award-info":[{"award-number":["RF1 AG057409"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 AG056259"],"award-info":[{"award-number":["R01 AG056259"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 AG061845"],"award-info":[{"award-number":["R01 AG061845"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J. Neurovirol."],"published-print":{"date-parts":[[2021,6]]},"DOI":"10.1007\/s13365-021-00970-4","type":"journal-article","created":{"date-parts":[[2021,4,19]],"date-time":"2021-04-19T21:03:32Z","timestamp":1618866212000},"page":"367-378","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["TCA cycle metabolic compromise due to an aberrant S-nitrosoproteome in HIV-associated neurocognitive disorder with methamphetamine use"],"prefix":"10.1007","volume":"27","author":[{"given":"Paschalis-Thomas","family":"Doulias","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomohiro","family":"Nakamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henry","family":"Scott","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scott R.","family":"McKercher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdullah","family":"Sultan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda","family":"Deal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew","family":"Albertolle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harry","family":"Ischiropoulos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3490-1259","authenticated-orcid":false,"given":"Stuart A.","family":"Lipton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,4,19]]},"reference":[{"key":"970_CR1","doi-asserted-by":"publisher","first-page":"724","DOI":"10.1016\/j.cmet.2011.08.016","volume":"14","author":"M Belanger","year":"2011","unstructured":"Belanger M, Allaman I, Magistretti PJ (2011) Brain energy metabolism: focus on astrocyte-neuron metabolic cooperation. Cell Metab 14:724\u2013738","journal-title":"Cell Metab"},{"key":"970_CR2","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1007\/BF03033915","volume":"12","author":"JL Cadet","year":"2007","unstructured":"Cadet JL, Krasnova IN (2007) Interactions of HIV and methamphetamine: cellular and molecular mechanisms of toxicity potentiation. Neurotox Res 12:181\u2013204","journal-title":"Neurotox Res"},{"key":"970_CR3","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1016\/0003-9861(89)90309-3","volume":"268","author":"DJ Carothers","year":"1989","unstructured":"Carothers DJ, Pons G, Patel MS (1989) Dihydrolipoamide dehydrogenase: functional similarities and divergent evolution of the pyridine nucleotide-disulfide oxidoreductases. Arch Biochem Biophys 268:409\u2013425","journal-title":"Arch Biochem Biophys"},{"issue":"Suppl 1","key":"970_CR4","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1111\/j.1360-0443.2006.01782.x","volume":"102","author":"L Chang","year":"2007","unstructured":"Chang L, Alicata D, Ernst T, Volkow N (2007) Structural and metabolic brain changes in the striatum associated with methamphetamine abuse. Addiction 102(Suppl 1):16\u201332","journal-title":"Addiction"},{"key":"970_CR5","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1176\/appi.ajp.162.2.361","volume":"162","author":"L Chang","year":"2005","unstructured":"Chang L, Ernst T, Speck O, Grob CS (2005) Additive effects of HIV and chronic methamphetamine use on brain metabolite abnormalities. Am J Psychiatry 162:361\u2013369","journal-title":"Am J Psychiatry"},{"key":"970_CR6","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1042\/BJ20100633","volume":"430","author":"ET Chouchani","year":"2010","unstructured":"Chouchani ET, Hurd TR, Nadtochiy SM, Brookes PS, Fearnley IM, Lilley KS, Smith RA, Murphy MP (2010) Identification of S-nitrosated mitochondrial proteins by S-nitrosothiol difference in gel electrophoresis (SNO-DIGE): implications for the regulation of mitochondrial function by reversible S-nitrosation. Biochem J 430:49\u201359","journal-title":"Biochem J"},{"key":"970_CR7","doi-asserted-by":"publisher","first-page":"101616","DOI":"10.1016\/j.pneurobio.2019.101616","volume":"181","author":"B Cotto","year":"2019","unstructured":"Cotto B, Natarajanseenivasan K, Langford D (2019) HIV-1 infection alters energy metabolism in the brain: contributions to HIV-associated neurocognitive disorders. Prog Neurobiol 181:101616","journal-title":"Prog Neurobiol"},{"key":"970_CR8","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1016\/j.abb.2003.12.017","volume":"423","author":"PC Dedon","year":"2004","unstructured":"Dedon PC, Tannenbaum SR (2004) Reactive nitrogen species in the chemical biology of inflammation. Arch Biochem Biophys 423:12\u201322","journal-title":"Arch Biochem Biophys"},{"key":"970_CR9","first-page":"522","volume":"5","author":"LA Demetrius","year":"2014","unstructured":"Demetrius LA, Magistretti PJ, Pellerin L (2014) Alzheimer\u2019s disease: the amyloid hypothesis and the Inverse Warburg effect. Front Physiol 5:522","journal-title":"Front Physiol"},{"issue":"361\u2013374","key":"970_CR10","first-page":"e4","volume":"26","author":"CM Diaz-Garcia","year":"2017","unstructured":"Diaz-Garcia CM, Mongeon R, Lahmann C, Koveal D, Zucker H, Yellen G (2017) Neuronal stimulation triggers neuronal glycolysis and not lactate uptake. Cell Metab 26(361\u2013374):e4","journal-title":"Cell Metab"},{"key":"970_CR11","doi-asserted-by":"publisher","first-page":"16958","DOI":"10.1073\/pnas.1008036107","volume":"107","author":"PT Doulias","year":"2010","unstructured":"Doulias PT, Greene JL, Greco TM, Tenopoulou M, Seeholzer SH, Dunbrack RL, Ischiropoulos H (2010) Structural profiling of endogenous S-nitrosocysteine residues reveals unique features that accommodate diverse mechanisms for protein S-nitrosylation. Proc Natl Acad Sci USA 107:16958\u201316963","journal-title":"Proc Natl Acad Sci USA"},{"key":"970_CR12","doi-asserted-by":"crossref","unstructured":"Doulias PT, Tenopoulou M, Greene JL, Raju K, Ischiropoulos H (2013a) Nitric oxide regulates mitochondrial fatty acid metabolism through reversible protein S-nitrosylation. Sci Signal 6: rs1","DOI":"10.1126\/scisignal.2003252"},{"key":"970_CR13","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1016\/j.jprot.2013.05.033","volume":"92","author":"PT Doulias","year":"2013","unstructured":"Doulias PT, Tenopoulou M, Raju K, Spruce LA, Seeholzer SH, Ischiropoulos H (2013) Site specific identification of endogenous S-nitrosocysteine proteomes. J Proteomics 92:195\u2013203","journal-title":"J Proteomics"},{"key":"970_CR14","doi-asserted-by":"publisher","first-page":"2502","DOI":"10.1111\/j.1460-9568.1995.tb01048.x","volume":"7","author":"EB Dreyer","year":"1995","unstructured":"Dreyer EB, Lipton SA (1995) The coat protein gp120 of HIV-1 inhibits astrocyte uptake of excitatory amino acids via macrophage arachidonic acid. Eur J Neurosci 7:2502\u20132507","journal-title":"Eur J Neurosci"},{"key":"970_CR15","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1038\/nbt.1545","volume":"27","author":"MT Forrester","year":"2009","unstructured":"Forrester MT, Thompson JW, Foster MW, Nogueira L, Moseley MA, Stamler JS (2009) Proteomic analysis of S-nitrosylation and denitrosylation by resin-assisted capture. Nat Biotechnol 27:557\u2013559","journal-title":"Nat Biotechnol"},{"key":"970_CR16","doi-asserted-by":"publisher","first-page":"25891","DOI":"10.1074\/jbc.M313853200","volume":"279","author":"MW Foster","year":"2004","unstructured":"Foster MW, Stamler JS (2004) New insights into protein S-nitrosylation. Mitochondria as a model system. J Biol Chem 279:25891\u201325897","journal-title":"J Biol Chem"},{"key":"970_CR17","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1016\/j.bbadis.2009.08.010","volume":"1802","author":"GE Gibson","year":"2010","unstructured":"Gibson GE, Starkov A, Blass JP, Ratan RR, Beal MF (2010) Cause and consequence: mitochondrial dysfunction initiates and propagates neuronal dysfunction, neuronal death and behavioral abnormalities in age-associated neurodegenerative diseases. Biochim Biophys Acta 1802:122\u2013134","journal-title":"Biochim Biophys Acta"},{"key":"970_CR18","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1038\/nrm1569","volume":"6","author":"DT Hess","year":"2005","unstructured":"Hess DT, Matsumoto A, Kim SO, Marshall HE, Stamler JS (2005) Protein S-nitrosylation: purview and parameters. Nat Rev Mol Cell Biol 6:150\u2013166","journal-title":"Nat Rev Mol Cell Biol"},{"key":"970_CR19","doi-asserted-by":"publisher","first-page":"988","DOI":"10.1038\/35073667","volume":"410","author":"M Kaul","year":"2001","unstructured":"Kaul M, Garden GA, Lipton SA (2001) Pathways to neuronal injury and apoptosis in HIV-associated dementia. Nature 410:988\u2013994","journal-title":"Nature"},{"key":"970_CR20","doi-asserted-by":"publisher","first-page":"988","DOI":"10.1021\/tx960036y","volume":"9","author":"M Keshive","year":"1996","unstructured":"Keshive M, Singh S, Wishnok JS, Tannenbaum SR, Deen WM (1996) Kinetics of S-nitrosation of thiols in nitric oxide solutions. Chem Res Toxicol 9:988\u2013993","journal-title":"Chem Res Toxicol"},{"key":"970_CR21","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/j.freeradbiomed.2009.10.026","volume":"48","author":"A Keszler","year":"2010","unstructured":"Keszler A, Zhang Y, Hogg N (2010) Reaction between nitric oxide, glutathione, and oxygen in the presence and absence of protein: How are S-nitrosothiols formed? Free Radic Biol Med 48:55\u201364","journal-title":"Free Radic Biol Med"},{"key":"970_CR22","doi-asserted-by":"publisher","first-page":"1087","DOI":"10.1016\/0896-6273(92)90130-6","volume":"8","author":"SZ Lei","year":"1992","unstructured":"Lei SZ, Pan ZH, Aggarwal SK, Chen HS, Hartman J, Sucher NJ, Lipton SA (1992) Effect of nitric oxide production on the redox modulatory site of the NMDA receptor-channel complex. Neuron 8:1087\u20131099","journal-title":"Neuron"},{"key":"970_CR23","doi-asserted-by":"publisher","first-page":"626","DOI":"10.1038\/364626a0","volume":"364","author":"SA Lipton","year":"1993","unstructured":"Lipton SA, Choi YB, Pan ZH, Lei SZ, Chen HS, Sucher NJ, Loscalzo J, Singel DJ, Stamler JS (1993) A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds. Nature 364:626\u2013632","journal-title":"Nature"},{"key":"970_CR24","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1016\/j.cmet.2015.10.010","volume":"23","author":"P Machler","year":"2016","unstructured":"Machler P, Wyss MT, Elsayed M, Stobart J, Gutierrez R, von Faber-Castell A, Kaelin V, Zuend M, San Martin A, Romero-Gomez I, Baeza-Lehnert F, Lengacher S, Schneider BL, Aebischer P, Magistretti PJ, Barros LF, Weber B (2016) In vivo evidence for a lactate gradient from astrocytes to neurons. Cell Metab 23:94\u2013102","journal-title":"Cell Metab"},{"key":"970_CR25","doi-asserted-by":"publisher","first-page":"2013","DOI":"10.1016\/j.freeradbiomed.2008.02.015","volume":"44","author":"E Madej","year":"2008","unstructured":"Madej E, Folkes LK, Wardman P, Czapski G, Goldstein S (2008) Thiyl radicals react with nitric oxide to form S-nitrosothiols with rate constants near the diffusion-controlled limit. Free Radic Biol Med 44:2013\u20132018","journal-title":"Free Radic Biol Med"},{"key":"970_CR26","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/j.freeradbiomed.2011.04.010","volume":"51","author":"A Martinez-Ruiz","year":"2011","unstructured":"Martinez-Ruiz A, Cadenas S, Lamas S (2011) Nitric oxide signaling: classical, less classical, and nonclassical mechanisms. Free Radic Biol Med 51:17\u201329","journal-title":"Free Radic Biol Med"},{"key":"970_CR27","doi-asserted-by":"publisher","first-page":"1551","DOI":"10.1038\/nprot.2013.092","volume":"8","author":"H Mi","year":"2013","unstructured":"Mi H, Muruganujan A, Casagrande JT, Thomas PD (2013) Large-scale gene function analysis with the PANTHER classification system. Nat Protoc 8:1551\u20131566","journal-title":"Nat Protoc"},{"key":"970_CR28","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1038\/nchembio720","volume":"1","author":"DA Mitchell","year":"2005","unstructured":"Mitchell DA, Marletta MA (2005) Thioredoxin catalyzes the S-nitrosation of the caspase-3 active site cysteine. Nat Chem Biol 1:154\u2013158","journal-title":"Nat Chem Biol"},{"key":"970_CR29","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1016\/j.tem.2017.10.004","volume":"28","author":"T Nakamura","year":"2017","unstructured":"Nakamura T, Lipton SA (2017) \u2019SNO\u2019-storms compromise protein activity and mitochondrial metabolism in neurodegenerative disorders. Trends Endocrinol Metab 28:879\u2013892","journal-title":"Trends Endocrinol Metab"},{"key":"970_CR30","doi-asserted-by":"crossref","unstructured":"Nakamura T, Oh CK, Liao L, Zhang X, Lopez KM, Gibbs D, Deal AK, Scott HR, Spencer B, Masliah E, Rissman RA, Yates JR 3rd, Lipton SA (2021) Noncanonical transnitrosylation network contributes to synapse loss in Alzheimer's disease. Science 371: eaaw0843","DOI":"10.1126\/science.aaw0843"},{"key":"970_CR31","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1016\/j.nbd.2015.03.017","volume":"84","author":"T Nakamura","year":"2015","unstructured":"Nakamura T, Prikhodko OA, Pirie E, Nagar S, Akhtar MW, Oh CK, McKercher SR, Ambasudhan R, Okamoto S, Lipton SA (2015) Aberrant protein S-nitrosylation contributes to the pathophysiology of neurodegenerative diseases. Neurobiol Dis 84:99\u2013108","journal-title":"Neurobiol Dis"},{"key":"970_CR32","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1016\/0076-6879(95)52022-8","volume":"252","author":"MS Patel","year":"1995","unstructured":"Patel MS, Vettakkorumakankav NN, Liu TC (1995) Dihydrolipoamide dehydrogenase: activity assays. Methods Enzymol 252:186\u2013195","journal-title":"Methods Enzymol"},{"key":"970_CR33","doi-asserted-by":"publisher","first-page":"ra68","DOI":"10.1126\/scisignal.aaa4312","volume":"8","author":"K Raju","year":"2015","unstructured":"Raju K, Doulias PT, Evans P, Krizman EN, Jackson JG, Horyn O, Daikhin Y, Nissim I, Yudkoff M, Nissim I, Sharp KA, Robinson MB, Ischiropoulos H (2015) Regulation of brain glutamate metabolism by nitric oxide and S-nitrosylation. Sci Signal 8:ra68","journal-title":"Sci Signal"},{"key":"970_CR34","doi-asserted-by":"publisher","first-page":"825","DOI":"10.1016\/j.cell.2013.12.042","volume":"156","author":"V Rangaraju","year":"2014","unstructured":"Rangaraju V, Calloway N, Ryan TA (2014) Activity-driven local ATP synthesis is required for synaptic function. Cell 156:825\u2013835","journal-title":"Cell"},{"issue":"73\u201384","key":"970_CR35","first-page":"e15","volume":"176","author":"V Rangaraju","year":"2019","unstructured":"Rangaraju V, Lauterbach M, Schuman EM (2019) Spatially stable mitochondrial compartments fuel local translation during plasticity. Cell 176(73\u201384):e15","journal-title":"Cell"},{"key":"970_CR36","doi-asserted-by":"publisher","first-page":"8200","DOI":"10.1523\/JNEUROSCI.1157-19.2019","volume":"39","author":"V Rangaraju","year":"2019","unstructured":"Rangaraju V, Lewis TL Jr, Hirabayashi Y, Bergami M, Motori E, Cartoni R, Kwon SK, Courchet J (2019) Pleiotropic mitochondria: the influence of mitochondria on neuronal development and disease. J Neurosci 39:8200\u20138208","journal-title":"J Neurosci"},{"key":"970_CR37","first-page":"162","volume":"1","author":"BC Reiner","year":"2009","unstructured":"Reiner BC, Keblesh JP, Xiong H (2009) Methamphetamine abuse, HIV infection, and neurotoxicity. Int J Physiol Pathophysiol Pharmacol 1:162\u2013179","journal-title":"Int J Physiol Pathophysiol Pharmacol"},{"key":"970_CR38","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1128\/AAC.01632-15","volume":"60","author":"AB Sanchez","year":"2016","unstructured":"Sanchez AB, Varano GP, de Rozieres CM, Maung R, Catalan IC, Dowling CC, Sejbuk NE, Hoefer MM, Kaul M (2016) Antiretrovirals, methamphetamine, and HIV-1 envelope Protein gp120 compromise neuronal energy homeostasis in association with various degrees of synaptic and neuritic damage. Antimicrob Agents Chemother 60:168\u2013179","journal-title":"Antimicrob Agents Chemother"},{"key":"970_CR39","doi-asserted-by":"publisher","first-page":"3987","DOI":"10.1016\/j.jprot.2012.05.006","volume":"75","author":"R Scheving","year":"2012","unstructured":"Scheving R, Wittig I, Heide H, Albuquerque B, Steger M, Brandt U, Tegeder I (2012) Protein S-nitrosylation and denitrosylation in the mouse spinal cord upon injury of the sciatic nerve. J Proteomics 75:3987\u20134004","journal-title":"J Proteomics"},{"key":"970_CR40","doi-asserted-by":"publisher","first-page":"4152","DOI":"10.1073\/pnas.1521318113","volume":"113","author":"U Seneviratne","year":"2016","unstructured":"Seneviratne U, Nott A, Bhat VB, Ravindra KC, Wishnok JS, Tsai LH, Tannenbaum SR (2016) S-Nitrosation of proteins relevant to Alzheimer\u2019s disease during early stages of neurodegeneration. Proc Natl Acad Sci USA 113:4152\u20134157","journal-title":"Proc Natl Acad Sci USA"},{"key":"970_CR41","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1016\/j.cbpa.2010.10.012","volume":"15","author":"D Seth","year":"2011","unstructured":"Seth D, Stamler JS (2011) The SNO-proteome: causation and classifications. Curr Opin Chem Biol 15:129\u2013136","journal-title":"Curr Opin Chem Biol"},{"key":"970_CR42","doi-asserted-by":"publisher","first-page":"498","DOI":"10.1016\/j.cbpa.2012.10.016","volume":"16","author":"BC Smith","year":"2012","unstructured":"Smith BC, Marletta MA (2012) Mechanisms of S-nitrosothiol formation and selectivity in nitric oxide signaling. Curr Opin Chem Biol 16:498\u2013506","journal-title":"Curr Opin Chem Biol"},{"key":"970_CR43","doi-asserted-by":"publisher","first-page":"10540","DOI":"10.1073\/pnas.88.23.10540","volume":"88","author":"CD Smith","year":"1991","unstructured":"Smith CD, Carney JM, Starke-Reed PE, Oliver CN, Stadtman ER, Floyd RA, Markesbery WR (1991) Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease. Proc Natl Acad Sci USA 88:10540\u201310543","journal-title":"Proc Natl Acad Sci USA"},{"key":"970_CR44","doi-asserted-by":"publisher","first-page":"495","DOI":"10.1007\/s11481-016-9699-0","volume":"11","author":"V Soontornniyomkij","year":"2016","unstructured":"Soontornniyomkij V, Kesby JP, Morgan EE, Bischoff-Grethe A, Minassian A, Brown GG, Grant I, Translational Methamphetamine ARCG (2016) Effects of HIV and methamphetamine on brain and behavior: evidence from human studies and animal models. J Neuroimmune Pharmacol 11:495\u2013510","journal-title":"J Neuroimmune Pharmacol"},{"key":"970_CR45","doi-asserted-by":"publisher","first-page":"1155","DOI":"10.1161\/CIRCRESAHA.107.155879","volume":"101","author":"J Sun","year":"2007","unstructured":"Sun J, Morgan M, Shen RF, Steenbergen C, Murphy E (2007) Preconditioning results in S-nitrosylation of proteins involved in regulation of mitochondrial energetics and calcium transport. Circ Res 101:1155\u20131163","journal-title":"Circ Res"},{"key":"970_CR46","doi-asserted-by":"publisher","first-page":"E2518","DOI":"10.1073\/pnas.1306832110","volume":"110","author":"M Talantova","year":"2013","unstructured":"Talantova M, Sanz-Blasco S, Zhang X, Xia P, Akhtar MW, Okamoto S, Dziewczapolski G, Nakamura T, Cao G, Pratt AE, Kang YJ, Tu S, Molokanova E, McKercher SR, Hires SA, Sason H, Stouffer DG, Buczynski MW, Solomon JP, Michael S, Powers ET, Kelly JW, Roberts A, Tong G, Fang-Newmeyer T, Parker J, Holland EA, Zhang D, Nakanishi N, Chen HS, Wolosker H, Wang Y, Parsons LH, Ambasudhan R, Masliah E, Heinemann SF, Pina-Crespo JC, Lipton SA (2013) A\u00df induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss. Proc Natl Acad Sci USA 110:E2518\u2013E2527","journal-title":"Proc Natl Acad Sci USA"},{"key":"970_CR47","doi-asserted-by":"publisher","first-page":"2335","DOI":"10.1098\/rstb.2005.1764","volume":"360","author":"L Tretter","year":"2005","unstructured":"Tretter L, Adam-Vizi V (2005) \u03b1-Ketoglutarate dehydrogenase: a target and generator of oxidative stress. Philos Trans R Soc Lond B Biol Sci 360:2335\u20132345","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"key":"970_CR48","doi-asserted-by":"publisher","first-page":"1236","DOI":"10.1111\/j.1460-9568.1997.tb01478.x","volume":"9","author":"D Trotti","year":"1997","unstructured":"Trotti D, Rizzini BL, Rossi D, Haugeto O, Racagni G, Danbolt NC, Volterra A (1997) Neuronal and glial glutamate transporters possess an SH-based redox regulatory mechanism. Eur J Neurosci 9:1236\u20131243","journal-title":"Eur J Neurosci"},{"key":"970_CR49","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1007\/s13365-014-0258-2","volume":"20","author":"FJ Vazquez-Santiago","year":"2014","unstructured":"Vazquez-Santiago FJ, Noel RJ Jr, Porter JT, Rivera-Amill V (2014) Glutamate metabolism and HIV-associated neurocognitive disorders. J Neurovirol 20:315\u2013331","journal-title":"J Neurovirol"},{"key":"970_CR50","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1038\/s41586-019-1095-5","volume":"568","author":"KHG Verschueren","year":"2019","unstructured":"Verschueren KHG, Blanchet C, Felix J, Dansercoer A, De Vos D, Bloch Y, Van Beeumen J, Svergun D, Gutsche I, Savvides SN, Verstraete K (2019) Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle. Nature 568:571\u2013575","journal-title":"Nature"},{"key":"970_CR51","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1016\/S0042-6822(03)00181-8","volume":"312","author":"Z Wang","year":"2003","unstructured":"Wang Z, Pekarskaya O, Bencheikh M, Chao W, Gelbard HA, Ghorpade A, Rothstein JD, Volsky DJ (2003) Reduced expression of glutamate transporter EAAT2 and impaired glutamate transport in human primary astrocytes exposed to HIV-1 or gp120. Virology 312:60\u201373","journal-title":"Virology"},{"key":"970_CR52","first-page":"341","volume":"28","author":"LJ Yan","year":"2012","unstructured":"Yan LJ, Liu L, Forster MJ (2012) Reversible inactivation of dihydrolipoamide dehydrogenase by Angeli\u2019s salt. Sheng Wu Wu Li Hsueh Bao 28:341\u2013350","journal-title":"Sheng Wu Wu Li Hsueh Bao"},{"key":"970_CR53","doi-asserted-by":"crossref","unstructured":"Zheng X, Boyer L, Jin M, Mertens J, Kim Y, Ma L, Ma L, Hamm M, Gage FH, Hunter T (2016) Metabolic reprogramming during neuronal differentiation from aerobic glycolysis to neuronal oxidative phosphorylation. eLife 5: e13374","DOI":"10.7554\/eLife.13374"}],"updated-by":[{"DOI":"10.1007\/s13365-021-00985-x","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2021,5,3]],"date-time":"2021-05-03T00:00:00Z","timestamp":1620000000000}}],"container-title":["Journal of NeuroVirology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13365-021-00970-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s13365-021-00970-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13365-021-00970-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,31]],"date-time":"2023-01-31T20:22:48Z","timestamp":1675196568000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s13365-021-00970-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,19]]},"references-count":53,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["970"],"URL":"https:\/\/doi.org\/10.1007\/s13365-021-00970-4","relation":{"correction":[{"id-type":"doi","id":"10.1007\/s13365-021-00985-x","asserted-by":"object"}]},"ISSN":["1355-0284","1538-2443"],"issn-type":[{"value":"1355-0284","type":"print"},{"value":"1538-2443","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4,19]]},"assertion":[{"value":"29 December 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 March 2021","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 March 2021","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 April 2021","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 May 2021","order":5,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Correction","order":6,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"A Correction to this paper has been published:","order":7,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"https:\/\/doi.org\/10.1007\/s13365-021-00985-x","URL":"https:\/\/doi.org\/10.1007\/s13365-021-00985-x","order":8,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The contents of the manuscript are solely the responsibility of the authors and do not necessarily represent the official view of the NNTC or NIH","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclaimer"}}]}}