{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T15:45:20Z","timestamp":1766159120355,"version":"3.37.3"},"reference-count":74,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/100000026","name":"National Institute on Drug Abuse","doi-asserted-by":"publisher","award":["DA044939","DA024461"],"award-info":[{"award-number":["DA044939","DA024461"]}],"id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J. Neurovirol."],"published-print":{"date-parts":[[2023,2]]},"DOI":"10.1007\/s13365-022-01107-x","type":"journal-article","created":{"date-parts":[[2023,2,28]],"date-time":"2023-02-28T15:03:13Z","timestamp":1677596593000},"page":"15-26","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Myelin regulatory factor is a target of individual and interactive effects of HIV-1 Tat and morphine in the striatum and pre-frontal cortex"],"prefix":"10.1007","volume":"29","author":[{"given":"Kelly M.","family":"Flounlacker","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yun Kyung","family":"Hahn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruqiang","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chloe A.","family":"Simons","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tao","family":"Tian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7886-0332","authenticated-orcid":false,"given":"Kurt F.","family":"Hauser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1455-0065","authenticated-orcid":false,"given":"Pamela E.","family":"Knapp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,2,28]]},"reference":[{"key":"1107_CR1","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1002\/jnr.10188","volume":"68","author":"K Akiyama","year":"2002","unstructured":"Akiyama K, Ichinose S, Omori A et al (2002) Study of expression of myelin basic proteins (MBPs) in developing rat brain using a novel antibody reacting with four major isoforms of MBP. J Neurosci Res 68:19\u201328. https:\/\/doi.org\/10.1002\/jnr.10188","journal-title":"J Neurosci Res"},{"key":"1107_CR2","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1097\/QAI.0b013e318249db17","volume":"59","author":"BM Ances","year":"1988","unstructured":"Ances BM, Ortega M, Vaida F et al (2012) Independent effects of HIV, aging, and HAART on brain volumetric measures. J Acquir Immune Defic Syndr\u00a0(1988)\u00a059:469\u2013477. https:\/\/doi.org\/10.1097\/QAI.0b013e318249db17","journal-title":"J Acquir Immune Defic Syndr"},{"key":"1107_CR3","doi-asserted-by":"publisher","first-page":"3328","DOI":"10.1523\/jneurosci.15-05-03328.1995","volume":"15","author":"U Arvidsson","year":"1995","unstructured":"Arvidsson U, Riedl M, Chakrabarti S et al (1995) Distribution and targeting of a \u03bc-opioid receptor (MOR1) in brain and spinal cord. J Neurosci 15:3328\u20133341. https:\/\/doi.org\/10.1523\/jneurosci.15-05-03328.1995","journal-title":"J Neurosci"},{"key":"1107_CR4","doi-asserted-by":"publisher","first-page":"753","DOI":"10.1097\/QAD.0000000000001398","volume":"31","author":"JM Balinang","year":"2017","unstructured":"Balinang JM, Masvekar RR, Hauser KF, Knapp PE (2017) Productive infection of human neural progenitor cells by R5 tropic HIV-1: opiate co-exposure heightens infectivity and functional vulnerability. AIDS 31:753\u2013764. https:\/\/doi.org\/10.1097\/QAD.0000000000001398","journal-title":"AIDS"},{"key":"1107_CR5","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1007\/s11481-006-9018-2","volume":"1","author":"JE Bell","year":"2006","unstructured":"Bell JE, Arango JC, Anthony IC (2006) Neurobiology of multiple insults: HIV-1-associated brain disorders in those who use illicit drugs. J Neuroimmune Pharmacol 1:182\u2013191. https:\/\/doi.org\/10.1007\/s11481-006-9018-2","journal-title":"J Neuroimmune Pharmacol"},{"key":"1107_CR6","doi-asserted-by":"publisher","first-page":"1414","DOI":"10.1002\/glia.20708","volume":"56","author":"AJ Bruce-Keller","year":"2008","unstructured":"Bruce-Keller AJ, Turchan-Cholewo J, Smart EJ et al (2008) Morphine causes rapid increases in glial activation and neuronal injury in the striatum of inducible HIV-1 tat transgenic mice. Glia 56:1414\u20131427. https:\/\/doi.org\/10.1002\/glia.20708","journal-title":"Glia"},{"key":"1107_CR7","doi-asserted-by":"publisher","first-page":"1001625","DOI":"10.1371\/journal.pbio.1001625","volume":"11","author":"H Bujalka","year":"2013","unstructured":"Bujalka H, Koenning M, Jackson S et al (2013) MYRF is a membrane-associated transcription factor that autoproteolytically cleaves to directly activate myelin genes. PLoS Biol 11:1001625. https:\/\/doi.org\/10.1371\/journal.pbio.1001625","journal-title":"PLoS Biol"},{"key":"1107_CR8","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1083\/jcb.201605065","volume":"215","author":"Y Cai","year":"2016","unstructured":"Cai Y, Yang L, Hu G et al (2016) Regulation of morphine-induced synaptic alterations: role of oxidative stress, ER stress, and autophagy. J Cell Biol 215:245\u2013258. https:\/\/doi.org\/10.1083\/jcb.201605065","journal-title":"J Cell Biol"},{"key":"1107_CR9","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/0162-3109(95)00033-6","volume":"31","author":"DJJ Carr","year":"1995","unstructured":"Carr DJJ, Serou M (1995) Exogenous and endogenous opioids as biological response modifiers. Immunopharmacology 31:59\u201371. https:\/\/doi.org\/10.1016\/0162-3109(95)00033-6","journal-title":"Immunopharmacology"},{"key":"1107_CR10","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41598-017-12758-w","volume":"7","author":"P Castellano","year":"2017","unstructured":"Castellano P, Prevedel L, Eugenin EA (2017) HIV-infected macrophages and microglia that survive acute infection become viral reservoirs by a mechanism involving Bim. Sci Rep 7:1\u201316. https:\/\/doi.org\/10.1038\/s41598-017-12758-w","journal-title":"Sci Rep"},{"key":"1107_CR11","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1097\/QAD.0000000000002404","volume":"34","author":"K Chang","year":"2020","unstructured":"Chang K, Premeaux TA, Cobigo Y et al (2020) Plasma inflammatory biomarkers link to diffusion tensor imaging metrics in virally suppressed HIV-infected individuals. AIDS 34:203\u2013213. https:\/\/doi.org\/10.1097\/QAD.0000000000002404","journal-title":"AIDS"},{"key":"1107_CR12","doi-asserted-by":"publisher","first-page":"1262","DOI":"10.1002\/jmri.25263","volume":"44","author":"DG Corr\u00eaa","year":"2016","unstructured":"Corr\u00eaa DG, Zimmermann N, Tukamoto G et al (2016) Longitudinal assessment of subcortical gray matter volume, cortical thickness, and white matter integrity in HIV-positive patients. J Magn Reson Imaging 44:1262\u20131269. https:\/\/doi.org\/10.1002\/jmri.25263","journal-title":"J Magn Reson Imaging"},{"key":"1107_CR13","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1007\/s13365-017-0524-1","volume":"23","author":"LA Cysique","year":"2017","unstructured":"Cysique LA, Soares JR, Geng G et al (2017) White matter measures are near normal in controlled HIV infection except in those with cognitive impairment and longer HIV duration. J Neurovirol 23:539\u2013547. https:\/\/doi.org\/10.1007\/s13365-017-0524-1","journal-title":"J Neurovirol"},{"key":"1107_CR14","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1016\/S0165-5728(97)00224-5","volume":"83","author":"RM Donahoe","year":"1998","unstructured":"Donahoe RM, Vlahov D (1998) Opiates as potential cofactors in progression of HIV-1 infections to AIDS. J Neuroimmunol 83:77\u201387. https:\/\/doi.org\/10.1016\/S0165-5728(97)00224-5","journal-title":"J Neuroimmunol"},{"key":"1107_CR15","doi-asserted-by":"publisher","first-page":"1715","DOI":"10.1007\/s00415-017-8503-2","volume":"264","author":"C Eggers","year":"2017","unstructured":"Eggers C, Arendt G, Hahn K et al (2017) HIV-1-associated neurocognitive disorder: epidemiology, pathogenesis, diagnosis, and treatment. J Neurol 264:1715\u20131727","journal-title":"J Neurol"},{"key":"1107_CR16","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1016\/j.cell.2009.04.031","volume":"138","author":"B Emery","year":"2009","unstructured":"Emery B, Agalliu D, Cahoy JD et al (2009) Myelin gene regulatory factor is a critical transcriptional regulator required for CNS myelination. Cell 138:172\u2013185. https:\/\/doi.org\/10.1016\/j.cell.2009.04.031","journal-title":"Cell"},{"key":"1107_CR17","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1016\/0006-8993(74)90111-5","volume":"74","author":"CA Fischer","year":"1974","unstructured":"Fischer CA, Morell P (1974) Turnover of proteins in myelin and myelin-like material of mouse brain. Brain Res 74:51\u201365. https:\/\/doi.org\/10.1016\/0006-8993(74)90111-5","journal-title":"Brain Res"},{"key":"1107_CR18","doi-asserted-by":"publisher","unstructured":"Ge SX, Son EW, Yao R (2018) iDEP: an integrated web application for differential expression and pathway analysis of RNA-Seq data. BMC Bioinformatics 19. https:\/\/doi.org\/10.1186\/s12859-018-2486-6","DOI":"10.1186\/s12859-018-2486-6"},{"key":"1107_CR19","doi-asserted-by":"publisher","first-page":"4958","DOI":"10.1002\/hbm.25592","volume":"42","author":"SA Hall","year":"2021","unstructured":"Hall SA, Bell RP, Davis SW et al (2021) Human immunodeficiency virus-related decreases in corpus callosal integrity and corresponding increases in functional connectivity. Hum Brain Mapp 42:4958\u20134972. https:\/\/doi.org\/10.1002\/hbm.25592","journal-title":"Hum Brain Mapp"},{"key":"1107_CR20","doi-asserted-by":"publisher","unstructured":"Hauser KF, Hahn YK, Adjan VV et al (2009) HIV-1 Tat and morphine have interactive effects on oligodendrocyte survival and morphology. Glia 194\u2013206. https:\/\/doi.org\/10.1002\/glia.20746","DOI":"10.1002\/glia.20746"},{"key":"1107_CR21","doi-asserted-by":"publisher","first-page":"2087","DOI":"10.1212\/WNL.0b013e318200d727","volume":"75","author":"RK Heaton","year":"2010","unstructured":"Heaton RK, Clifford DB, Franklin DR et al (2010) HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy: Charter Study. Neurology 75:2087\u20132096. https:\/\/doi.org\/10.1212\/WNL.0b013e318200d727","journal-title":"Neurology"},{"issue":"Suppl 2","key":"1107_CR22","doi-asserted-by":"publisher","first-page":"S145","DOI":"10.1097\/QAD.0000000000002268","volume":"33","author":"LJ Henderson","year":"2019","unstructured":"Henderson LJ, Johnson TP, Smith BR et al (2019) Presence of Tat and transactivation response element in spinal fluid despite antiretroviral therapy. AIDS 33(Suppl 2):S145\u2013S157. https:\/\/doi.org\/10.1097\/QAD.0000000000002268","journal-title":"AIDS"},{"key":"1107_CR23","doi-asserted-by":"publisher","first-page":"1365","DOI":"10.1038\/nn.2644","volume":"13","author":"JD Hoeck","year":"2010","unstructured":"Hoeck JD, Jandke A, Blake SM et al (2010) Fbw7 controls neural stem cell differentiation and progenitor apoptosis via Notch and c-Jun. Nat Neurosci 13:1365\u20131372. https:\/\/doi.org\/10.1038\/nn.2644","journal-title":"Nat Neurosci"},{"key":"1107_CR24","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1038\/nmeth.3252","volume":"12","author":"W Huber","year":"2015","unstructured":"Huber W, Carey VJ, Gentleman R et al (2015) Orchestrating high-throughput genomic analysis with Bioconductor. Nat Methods 12:115\u2013121. https:\/\/doi.org\/10.1038\/nmeth.3252","journal-title":"Nat Methods"},{"key":"1107_CR25","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fnana.2017.00088","volume":"11","author":"M Jankiewicz","year":"2017","unstructured":"Jankiewicz M, Holmes MJ, Taylor PA et al (2017) White matter abnormalities in children with HIV infection and exposure. Front Neuroanat 11:1\u20139. https:\/\/doi.org\/10.3389\/fnana.2017.00088","journal-title":"Front Neuroanat"},{"key":"1107_CR26","doi-asserted-by":"publisher","first-page":"1093","DOI":"10.1097\/NEN.0000000000000255","volume":"74","author":"BK Jensen","year":"2015","unstructured":"Jensen BK, Monnerie H, Mannell MV et al (2015) Altered oligodendrocyte maturation and myelin maintenance: the role of antiretrovirals in HIV-associated neurocognitive disorders. J Neuropathol Exp Neurol 74:1093\u20131118. https:\/\/doi.org\/10.1097\/NEN.0000000000000255","journal-title":"J Neuropathol Exp Neurol"},{"key":"1107_CR27","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2019.146397","volume":"1724","author":"BK Jensen","year":"2019","unstructured":"Jensen BK, Roth LM, Grinspan JB, Jordan-Sciutto KL (2019) White matter loss and oligodendrocyte dysfunction in HIV: a consequence of the infection, the antiretroviral therapy or both? Brain Res 1724:146397","journal-title":"Brain Res"},{"key":"1107_CR28","doi-asserted-by":"publisher","first-page":"13588","DOI":"10.1073\/pnas.1308673110","volume":"110","author":"TP Johnson","year":"2013","unstructured":"Johnson TP, Patel K, Johnson KR et al (2013) Induction of IL-17 and nonclassical T-cell activation by HIV-Tat protein. Proc Natl Acad Sci U S A 110:13588\u201313593. https:\/\/doi.org\/10.1073\/pnas.1308673110","journal-title":"Proc Natl Acad Sci U S A"},{"key":"1107_CR29","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1002\/jnr.490210110","volume":"21","author":"J Kamholz","year":"1988","unstructured":"Kamholz J, Toffenetti J, Lazzarini RA (1988) Organization and expression of the human myelin basic protein gene. J Neurosci Res 21:62\u201370. https:\/\/doi.org\/10.1002\/jnr.490210110","journal-title":"J Neurosci Res"},{"key":"1107_CR30","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1089\/aid.2020.0039","volume":"36","author":"MY Karris","year":"2020","unstructured":"Karris MY, Berko J, Mazonson PD et al (2020) Association of pain and pain medication use with multiple characteristics of older people living with HIV. AIDS Res Hum Retroviruses 36:663\u2013669. https:\/\/doi.org\/10.1089\/aid.2020.0039","journal-title":"AIDS Res Hum Retroviruses"},{"key":"1107_CR31","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1002\/(SICI)1098-1136(199802)22:2<189::AID-GLIA10>3.0.CO;2-U","volume":"22","author":"PE Knapp","year":"1998","unstructured":"Knapp PE, Maderspach K, Hauser KF (1998) Endogenous opioid system in developing normal and jimpy oligodendrocytes: \u03bc and \u03ba opioid receptors mediate differential mitogenic and growth responses. Glia 22:189\u2013201. https:\/\/doi.org\/10.1002\/(SICI)1098-1136(199802)22:2%3c189::AID-GLIA10%3e3.0.CO;2-U","journal-title":"Glia"},{"key":"1107_CR32","doi-asserted-by":"publisher","first-page":"12528","DOI":"10.1523\/JNEUROSCI.1069-12.2012","volume":"32","author":"M Koenning","year":"2012","unstructured":"Koenning M, Jackson S, Hay CM et al (2012) Myelin gene regulatory factor is required for maintenance of myelin and mature oligodendrocyte identity in the adult CNS. J Neurosci 32:12528\u201312542. https:\/\/doi.org\/10.1523\/JNEUROSCI.1069-12.2012","journal-title":"J Neurosci"},{"key":"1107_CR33","doi-asserted-by":"publisher","first-page":"1066","DOI":"10.1007\/s00415-010-5883-y","volume":"258","author":"M K\u00fcper","year":"2011","unstructured":"K\u00fcper M, Rabe K, Esser S et al (2011) Structural gray and white matter changes in patients with HIV. J Neurol 258:1066\u20131075. https:\/\/doi.org\/10.1007\/s00415-010-5883-y","journal-title":"J Neurol"},{"key":"1107_CR34","doi-asserted-by":"crossref","unstructured":"Langford TD, Letendre SL, Larrea GJ, Masliah E (2003) Changing patterns in the neuropathogenesis of HIV during the HAART era. In: Brain Pathology. Intern Soc Neuropathol 195\u2013210","DOI":"10.1111\/j.1750-3639.2003.tb00019.x"},{"key":"1107_CR35","doi-asserted-by":"publisher","first-page":"7319","DOI":"10.1128\/jvi.78.14.7319-7328.2004","volume":"78","author":"DMP Lawrence","year":"2004","unstructured":"Lawrence DMP, Durham LC, Schwartz L et al (2004) Human immunodeficiency virus type 1 infection of human brain-derived progenitor cells. J Virol 78:7319\u20137328. https:\/\/doi.org\/10.1128\/jvi.78.14.7319-7328.2004","journal-title":"J Virol"},{"key":"1107_CR36","doi-asserted-by":"publisher","unstructured":"Lutgen V, Narasipura SD, Barbian HJ et al (2020) HIV infects astrocytes in vivo and egresses from the brain to the periphery. PLoS Pathog 16. https:\/\/doi.org\/10.1371\/journal.ppat.1008381","DOI":"10.1371\/journal.ppat.1008381"},{"key":"1107_CR37","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1016\/0166-2236(95)93946-U","volume":"18","author":"A Mansour","year":"1995","unstructured":"Mansour A, Fox CA, Akil H, Watson SJ (1995) Opioid-receptor mRNA expression in the rat CNS: anatomical and functional implications. Trends Neurosci 18:22\u201329","journal-title":"Trends Neurosci"},{"key":"1107_CR38","doi-asserted-by":"publisher","first-page":"308","DOI":"10.1016\/0166-2236(88)90093-8","volume":"11","author":"A Mansour","year":"1988","unstructured":"Mansour A, Khachaturian H, Lewis ME et al (1988) Anatomy of CNS opioid receptors. Trends Neurosci 11:308\u2013314","journal-title":"Trends Neurosci"},{"key":"1107_CR39","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1007\/s13365-016-0447-2","volume":"22","author":"WD Marks","year":"2016","unstructured":"Marks WD, Paris JJ, Schier CJ et al (2016) HIV-1 Tat causes cognitive deficits and selective loss of parvalbumin, somatostatin, and neuronal nitric oxide synthase expressing hippocampal CA1 interneuron subpopulations. J Neurovirol 22:747\u2013762. https:\/\/doi.org\/10.1007\/s13365-016-0447-2","journal-title":"J Neurovirol"},{"key":"1107_CR40","doi-asserted-by":"publisher","first-page":"488","DOI":"10.1007\/s13365-018-0639-z","volume":"24","author":"E Martin","year":"2018","unstructured":"Martin E, Keutmann MK, Fogel JS et al (2018) Verbal and spatial working memory among drug-using HIV-infected men and women. J Neurovirol 24:488\u2013497. https:\/\/doi.org\/10.1007\/s13365-018-0639-z","journal-title":"J Neurovirol"},{"key":"1107_CR41","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.mcn.2015.01.001","volume":"65","author":"RR Masvekar","year":"2015","unstructured":"Masvekar RR, El-Hage N, Hauser KF, Knapp PE (2015) GSK3\u03b2-activation is a point of convergence for HIV-1 and opiate-mediated interactive neurotoxicity. Mol Cell Neurosci 65:11\u201320. https:\/\/doi.org\/10.1016\/j.mcn.2015.01.001","journal-title":"Mol Cell Neurosci"},{"key":"1107_CR42","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1016\/j.bbrc.2011.06.092","volume":"411","author":"C McCaig","year":"2011","unstructured":"McCaig C, Potter L, Abramczyk O, Murray JT (2011) Phosphorylation of NDRG1 is temporally and spatially controlled during the cell cycle. Biochem Biophys Res Commun 411:227\u2013234. https:\/\/doi.org\/10.1016\/j.bbrc.2011.06.092","journal-title":"Biochem Biophys Res Commun"},{"key":"1107_CR43","doi-asserted-by":"publisher","first-page":"4288","DOI":"10.1093\/nar\/gks042","volume":"40","author":"DJ McCarthy","year":"2012","unstructured":"McCarthy DJ, Chen Y, Smyth GK (2012) Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation. Nucleic Acids Res 40:4288\u20134297. https:\/\/doi.org\/10.1093\/nar\/gks042","journal-title":"Nucleic Acids Res"},{"key":"1107_CR44","doi-asserted-by":"publisher","unstructured":"Micheva KD, Wolman D, Mensh BD et al (2016) A large fraction of neocortical myelin ensheathes axons of local inhibitory neurons. Elife 5. https:\/\/doi.org\/10.7554\/eLife.15784","DOI":"10.7554\/eLife.15784"},{"key":"1107_CR45","doi-asserted-by":"publisher","first-page":"1133","DOI":"10.1016\/j.neuropsychologia.2009.12.015","volume":"48","author":"EM M\u00fcller-Oehring","year":"2010","unstructured":"M\u00fcller-Oehring EM, Schulte T, Rosenbloom MJ et al (2010) Callosal degradation in HIV-1 infection predicts hierarchical perception: a DTI study. Neuropsychologia 48:1133\u20131143. https:\/\/doi.org\/10.1016\/j.neuropsychologia.2009.12.015","journal-title":"Neuropsychologia"},{"key":"1107_CR46","doi-asserted-by":"publisher","first-page":"5705","DOI":"10.1074\/jbc.RA117.000741","volume":"293","author":"S Nakayama","year":"2018","unstructured":"Nakayama S, Yumimoto K, Kawamura A, Nakayama KI (2018) Degradation of the endoplasmic reticulum\u2013anchored transcription factor MyRF by the ubiquitin ligase SCFFbxw7 in a manner dependent on the kinase GSK-3. J Biol Chem 293:5705\u20135714. https:\/\/doi.org\/10.1074\/jbc.RA117.000741","journal-title":"J Biol Chem"},{"key":"1107_CR47","doi-asserted-by":"publisher","unstructured":"Nelson HN, Treichel AJ, Eggum EN et al (2020) Individual neuronal subtypes control initial myelin sheath growth and stabilization. Neural Dev 15. https:\/\/doi.org\/10.1186\/s13064-020-00149-3","DOI":"10.1186\/s13064-020-00149-3"},{"key":"1107_CR48","unstructured":"ONUSIDA\/UNAIDS (2020) Global HIV & AIDS statistics \u2014 2020 fact sheet | UNAIDS. In: unaids.org. https:\/\/www.unaids.org\/en\/resources\/fact-sheet. Accessed 8 Dec 2020"},{"key":"1107_CR49","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1016\/j.bbi.2016.01.007","volume":"55","author":"JJ Paris","year":"2016","unstructured":"Paris JJ, Zou SP, Hahn YK et al (2016) 5\u03b1-reduced progestogens ameliorate mood-related behavioral pathology, neurotoxicity, and microgliosis associated with exposure to HIV-1 Tat. Brain Behav Immun 55:202\u2013214. https:\/\/doi.org\/10.1016\/j.bbi.2016.01.007","journal-title":"Brain Behav Immun"},{"key":"1107_CR50","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1007\/s13365-017-0594-0","volume":"24","author":"S Perez","year":"2018","unstructured":"Perez S, Johnson AM,\u00a0Xiang SH, et al (2018) Persistence of SIV in the brain of SIV-infected Chinese rhesus macaques with or without antiretroviral therapy. J Neurovirol 24:62\u201374. https:\/\/doi.org\/10.1007\/s13365-017-0594-0","journal-title":"J Neurovirol"},{"key":"1107_CR51","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1016\/S0925-4927(00)00082-2","volume":"106","author":"N Pomara","year":"2001","unstructured":"Pomara N, Crandall DT, Choi SJ et al (2001) White matter abnormalities in HIV-1 infection: a diffusion tensor imaging study. Psychiatry Res Neuroimaging 106:15\u201324. https:\/\/doi.org\/10.1016\/S0925-4927(00)00082-2","journal-title":"Psychiatry Res Neuroimaging"},{"key":"1107_CR52","doi-asserted-by":"publisher","first-page":"1348","DOI":"10.1038\/emboj.2010.32","volume":"29","author":"F Rayne","year":"2010","unstructured":"Rayne F, Debaisieux S, Yezid H et al (2010) Phosphatidylinositol-(4,5)-bisphosphate enables efficient secretion of HIV-1 Tat by infected T-cells. EMBO J 29:1348\u20131362. https:\/\/doi.org\/10.1038\/emboj.2010.32","journal-title":"EMBO J"},{"key":"1107_CR53","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1097\/01.wnn.0000182832.54697.5c","volume":"19","author":"D Rodr\u00edguez Salgado","year":"2006","unstructured":"Rodr\u00edguez Salgado D, Rodr\u00edguez \u00c1lvarez M, Seoane Pesqueira G (2006) Neuropsychological impairment among asymptomatic HIV-positive former intravenous drug users. Cogn Behav Neurol 19:95\u2013104. https:\/\/doi.org\/10.1097\/01.wnn.0000182832.54697.5c","journal-title":"Cogn Behav Neurol"},{"key":"1107_CR54","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1097\/QAI.0000000000002410","volume":"85","author":"CA Sabin","year":"2020","unstructured":"Sabin CA, Harding R, Doyle N et al (2020) Associations between widespread pain and sleep quality in people with HIV. J Acquir Immune Defic Syndr 85:106\u2013112. https:\/\/doi.org\/10.1097\/QAI.0000000000002410","journal-title":"J Acquir Immune Defic Syndr"},{"key":"1107_CR55","doi-asserted-by":"publisher","first-page":"5758","DOI":"10.1523\/JNEUROSCI.0622-17.2017","volume":"37","author":"CJ Schier","year":"2017","unstructured":"Schier CJ, Marks WD, Paris JJ et al (2017) Selective vulnerability of striatal D2 versus D1 dopamine receptor-expressing medium spiny neurons in HIV-1 tat transgenic male mice. J Neurosci 37:5758\u20135769. https:\/\/doi.org\/10.1523\/JNEUROSCI.0622-17.2017","journal-title":"J Neurosci"},{"key":"1107_CR56","doi-asserted-by":"publisher","first-page":"1427","DOI":"10.1111\/j.1471-4159.1981.tb00582.x","volume":"36","author":"R Shapira","year":"1981","unstructured":"Shapira R, Wilhelmi MR, Kibler RF (1981) Turnover of myelin proteins of rat brain, determined in fractions separated by sedimentation in a continuous sucrose gradient. J Neurochem 36:1427\u20131432. https:\/\/doi.org\/10.1111\/j.1471-4159.1981.tb00582.x","journal-title":"J Neurochem"},{"key":"1107_CR57","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1080\/13550280390201704","volume":"9","author":"L Song","year":"2003","unstructured":"Song L, Nath A, Geiger JD et al (2003) Human immunodeficiency virus type 1 Tat protein directly activates neuronal N-methyl-D-aspartate receptors at an allosteric zinc-sensitive site. J Neurovirol 9:399\u2013403. https:\/\/doi.org\/10.1080\/13550280390201704","journal-title":"J Neurovirol"},{"key":"1107_CR58","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2019.10.013","author":"PE Steadman","year":"2020","unstructured":"Steadman PE, Xia F, Ahmed M et al (2020) Disruption of Oligodendrogenesis Impairs Memory Consolidation in Adult Mice in Brief. https:\/\/doi.org\/10.1016\/j.neuron.2019.10.013","journal-title":"Disruption of Oligodendrogenesis Impairs Memory Consolidation in Adult Mice in Brief"},{"key":"1107_CR59","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1002\/glia.1097","volume":"36","author":"A Stiene-Martin","year":"2001","unstructured":"Stiene-Martin A, Knapp PE, Martin K et al (2001) Opioid system diversity in developing neurons, astroglia, and oligodendroglia in the subventricular zone and striatum: impact on gliogenesis in vivo. Glia 36:78\u201388. https:\/\/doi.org\/10.1002\/glia.1097","journal-title":"Glia"},{"key":"1107_CR60","doi-asserted-by":"publisher","unstructured":"Stubbe-Drger B, Deppe M, Mohammadi S et al (2012) Early microstructural white matter changes in patients with HIV: a diffusion tensor imaging study. BMC Neurol 12. https:\/\/doi.org\/10.1186\/1471-2377-12-23","DOI":"10.1186\/1471-2377-12-23"},{"key":"1107_CR61","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1007\/s11682-009-9086-z","volume":"4","author":"DF Tate","year":"2010","unstructured":"Tate DF, Conley J, Paul RH et al (2010) Quantitative diffusion tensor imaging tractography metrics are associated with cognitive performance among HIV-infected patients. Brain Imaging Behav 4:68\u201379. https:\/\/doi.org\/10.1007\/s11682-009-9086-z","journal-title":"Brain Imaging Behav"},{"key":"1107_CR62","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1126\/science.1249766","volume":"344","author":"GS Tomassy","year":"1979","unstructured":"Tomassy GS, Berger DR, Chen HH et al (2014) Distinct profiles of myelin distribution along single axons of pyramidal neurons in the neocortex. Science\u00a0(1979)\u00a0344:319\u2013324","journal-title":"Science"},{"key":"1107_CR63","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1016\/j.tcb.2015.09.002","volume":"26","author":"GS Tomassy","year":"2016","unstructured":"Tomassy GS, Dershowitz LB, Arlotta P (2016) Diversity matters: a revised guide to myelination. Trends Cell Biol 26:135\u2013147","journal-title":"Trends Cell Biol"},{"key":"1107_CR64","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1083\/jcb.121.2.461","volume":"121","author":"BE Vogel","year":"1993","unstructured":"Vogel BE, Lee SJ, Hildebrand A et al (1993) A novel integrin specificity exemplified by binding of the \u03b1(v)\u03b25 integrin to the basic domain of the HIV Tat protein and vitronectin. J Cell Biol 121:461\u2013468. https:\/\/doi.org\/10.1083\/jcb.121.2.461","journal-title":"J Cell Biol"},{"key":"1107_CR65","doi-asserted-by":"publisher","first-page":"422","DOI":"10.1007\/s13365-016-0509-5","volume":"23","author":"C Watson","year":"2017","unstructured":"Watson C, Busovaca E, Foley JM et al (2017) White matter hyperintensities correlate to cognition and fiber tract integrity in older adults with HIV. J Neurovirol 23:422\u2013429. https:\/\/doi.org\/10.1007\/s13365-016-0509-5","journal-title":"J Neurovirol"},{"key":"1107_CR66","doi-asserted-by":"publisher","first-page":"11466","DOI":"10.1073\/pnas.97.21.11466","volume":"97","author":"H Xiao","year":"2000","unstructured":"Xiao H, Neuveut C, Tiffany HL et al (2000) Selective CXCR4 antagonism by Tat: implications for in vivo expansion of coreceptor use by HIV-1. Proc Natl Acad Sci U S A 97:11466\u201311471. https:\/\/doi.org\/10.1073\/pnas.97.21.11466","journal-title":"Proc Natl Acad Sci U S A"},{"key":"1107_CR67","doi-asserted-by":"crossref","unstructured":"Yang Y, Zhou X, Liu X et al (2021) Implications of FBXW7 in neurodevelopment and neurodegeneration: molecular mechanisms and therapeutic potential. Front Cell Neurosci 15","DOI":"10.3389\/fncel.2021.736008"},{"key":"1107_CR68","doi-asserted-by":"publisher","unstructured":"Yin P, Liu Q, Pan Y et al (2020) Phosphorylation of myelin regulatory factor by PRKG 2 mediates demyelination in Huntington\u2019s disease . EMBO Rep 21. https:\/\/doi.org\/10.15252\/embr.201949783","DOI":"10.15252\/embr.201949783"},{"key":"1107_CR69","doi-asserted-by":"publisher","first-page":"11929","DOI":"10.1523\/JNEUROSCI.1860-14.2014","volume":"34","author":"Y Zhang","year":"2014","unstructured":"Zhang Y, Chen K, Sloan SA et al (2014) An RNA-sequencing transcriptome and splicing database of glia, neurons, and vascular cells of the cerebral cortex. J Neurosci 34:11929\u201311947. https:\/\/doi.org\/10.1523\/JNEUROSCI.1860-14.2014","journal-title":"J Neurosci"},{"key":"1107_CR70","doi-asserted-by":"publisher","first-page":"2799","DOI":"10.1016\/j.celrep.2019.05.018","volume":"27","author":"M Zonouzi","year":"2019","unstructured":"Zonouzi M, Berger D, Jokhi V et al (2019) Individual oligodendrocytes show bias for inhibitory axons in the neocortex. Cell Rep 27:2799-2808.e3. https:\/\/doi.org\/10.1016\/j.celrep.2019.05.018","journal-title":"Cell Rep"},{"key":"1107_CR71","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1111\/jnc.14668","volume":"149","author":"S Zou","year":"2019","unstructured":"Zou S, Balinang JM, Paris JJ et al (2019) Effects of HIV-1 Tat on oligodendrocyte viability are mediated by CaMKII\u03b2\u2013GSK3\u03b2 interactions. J Neurochem 149:98\u2013110. https:\/\/doi.org\/10.1111\/jnc.14668","journal-title":"J Neurochem"},{"key":"1107_CR72","doi-asserted-by":"publisher","unstructured":"Zou S, Fitting S, Hahn Y-K et al (2011) Morphine potentiates neurodegenerative effects of HIV-1 Tat through actions at m-opioid receptor-expressing glia. Brain 3613\u20133628. https:\/\/doi.org\/10.1093\/brain\/awr281","DOI":"10.1093\/brain\/awr281"},{"key":"1107_CR73","doi-asserted-by":"publisher","first-page":"11384","DOI":"10.1523\/JNEUROSCI.4740-14.2015","volume":"35","author":"S Zou","year":"2015","unstructured":"Zou S, Fuss B, Fitting S et al (2015) Oligodendrocytes are targets of HIV-1 tat: NMDA and AMPA receptor-mediated effects on survival and development. J Neurosci 35:11384\u201311398. https:\/\/doi.org\/10.1523\/JNEUROSCI.4740-14.2015","journal-title":"J Neurosci"},{"key":"1107_CR74","doi-asserted-by":"publisher","first-page":"914","DOI":"10.1016\/j.conb.2013.06.005","volume":"23","author":"JB Zuchero","year":"2013","unstructured":"Zuchero JB, Barres BA (2013) Intrinsic and extrinsic control of oligodendrocyte development. Curr Opin Neurobiol 23:914\u2013920","journal-title":"Curr Opin Neurobiol"}],"container-title":["Journal of NeuroVirology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13365-022-01107-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s13365-022-01107-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13365-022-01107-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,11]],"date-time":"2023-04-11T14:56:35Z","timestamp":1681224995000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s13365-022-01107-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2]]},"references-count":74,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,2]]}},"alternative-id":["1107"],"URL":"https:\/\/doi.org\/10.1007\/s13365-022-01107-x","relation":{},"ISSN":["1355-0284","1538-2443"],"issn-type":[{"type":"print","value":"1355-0284"},{"type":"electronic","value":"1538-2443"}],"subject":[],"published":{"date-parts":[[2023,2]]},"assertion":[{"value":"23 November 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 November 2022","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 November 2022","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 February 2023","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}