{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:59:32Z","timestamp":1772121572891,"version":"3.50.1"},"reference-count":55,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T00:00:00Z","timestamp":1772064000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T00:00:00Z","timestamp":1772064000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/100024033","name":"AIM-AHEAD","doi-asserted-by":"crossref","award":["OTA-21-017"],"award-info":[{"award-number":["OTA-21-017"]}],"id":[{"id":"10.13039\/100024033","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100007815","name":"District of Columbia Developmental Center for AIDS Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007815","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Georgetown-Howard Universities Center for Clinical and Translational Sciences"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J. Neurovirol."],"DOI":"10.1007\/s13365-025-01301-7","type":"journal-article","created":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:01:23Z","timestamp":1772118083000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Limbic and whole-brain functional connectivity in non-substance abusers with human immunodeficiency virus (HIV)"],"prefix":"10.1007","author":[{"given":"Stuart D.","family":"Washington","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anisa","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kehinde","family":"Omisore","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cedric","family":"Cole","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomilowo","family":"Abijo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashley","family":"VanMeter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marjorie C.","family":"Gondr\u00e9-Lewis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,2,26]]},"reference":[{"issue":"2","key":"1301_CR1","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1007\/s13365-019-00823-1","volume":"26","author":"AZ Abidin","year":"2020","unstructured":"Abidin AZ, AM DS, Schifitto G, Wismuller A (2020) Detecting cognitive impairment in HIV-infected individuals using mutual connectivity analysis of resting state functional MRI. J Neurovirol 26(2):188\u2013200. https:\/\/doi.org\/10.1007\/s13365-019-00823-1","journal-title":"J Neurovirol"},{"key":"1301_CR2","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1038\/s42003-019-0611-3","volume":"2","author":"PN Alves","year":"2019","unstructured":"Alves PN, Foulon C, Karolis V, Bzdok D, Margulies DS, Volle E, de Thiebaut M (2019) An improved neuroanatomical model of the default-mode network reconciles previous neuroimaging and neuropathological findings. Commun Biol 2:370. https:\/\/doi.org\/10.1038\/s42003-019-0611-3","journal-title":"Commun Biol"},{"key":"1301_CR3","doi-asserted-by":"publisher","first-page":"324","DOI":"10.1016\/j.neuroimage.2014.01.032","volume":"91","author":"JR Andrews-Hanna","year":"2014","unstructured":"Andrews-Hanna JR, Saxe R, Yarkoni T (2014) Contributions of episodic retrieval and mentalizing to autobiographical thought: evidence from functional neuroimaging, resting-state connectivity, and fMRI meta-analyses. Neuroimage 91:324\u2013335. https:\/\/doi.org\/10.1016\/j.neuroimage.2014.01.032","journal-title":"Neuroimage"},{"issue":"1","key":"1301_CR4","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1186\/s12981-023-00511-5","volume":"20","author":"R Bai","year":"2023","unstructured":"Bai R, Song C, Lv S, Chang L, Hua W, Weng W, Wu H, Dai L (2023) Role of microglia in HIV-1 infection. AIDS Res Ther 20(1):16. https:\/\/doi.org\/10.1186\/s12981-023-00511-5","journal-title":"AIDS Res Ther"},{"issue":"1","key":"1301_CR5","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1038\/s42003-020-01602-z","volume":"4","author":"T Brandman","year":"2021","unstructured":"Brandman T, Malach R, Simony E (2021) The surprising role of the default mode network in naturalistic perception. Commun Biol 4(1):79. https:\/\/doi.org\/10.1038\/s42003-020-01602-z","journal-title":"Commun Biol"},{"issue":"8","key":"1301_CR6","doi-asserted-by":"publisher","first-page":"1430","DOI":"10.1007\/s10461-014-0970-1","volume":"19","author":"VE Bryant","year":"2015","unstructured":"Bryant VE, Whitehead NE, Burrell LE 2nd, Dotson VM, Cook RL, Malloy P, Devlin K, Cohen RA (2015) Depression and apathy among people living with HIV: implications for treatment of HIV associated neurocognitive disorders. AIDS Behav 19(8):1430\u20131437. https:\/\/doi.org\/10.1007\/s10461-014-0970-1","journal-title":"AIDS Behav"},{"issue":"11","key":"1301_CR7","doi-asserted-by":"publisher","first-page":"1688","DOI":"10.1212\/01.wnl.0000218305.09183.70","volume":"66","author":"JM Castelo","year":"2006","unstructured":"Castelo JM, Sherman SJ, Courtney MG, Melrose RJ, Stern CE (2006) Altered hippocampal-prefrontal activation in HIV patients during episodic memory encoding. Neurology 66(11):1688\u20131695. https:\/\/doi.org\/10.1212\/01.wnl.0000218305.09183.70","journal-title":"Neurology"},{"issue":"11","key":"1301_CR8","doi-asserted-by":"publisher","first-page":"1155","DOI":"10.1089\/AID.2017.0004","volume":"33","author":"JJ Cenker","year":"2017","unstructured":"Cenker JJ, Stultz RD, McDonald D (2017) Brain microglial cells are highly susceptible to HIV-1 infection and spread. AIDS Res Hum Retroviruses 33(11):1155\u20131165. https:\/\/doi.org\/10.1089\/AID.2017.0004","journal-title":"AIDS Res Hum Retroviruses"},{"issue":"8","key":"1301_CR9","doi-asserted-by":"publisher","first-page":"1623","DOI":"10.3174\/ajnr.A5246","volume":"38","author":"JR Chaganti","year":"2017","unstructured":"Chaganti JR, Heinecke A, Gates TM, Moffat KJ, Brew BJ (2017) Functional connectivity in virally suppressed patients with HIV-associated neurocognitive disorder: a resting-state analysis. AJNR Am J Neuroradiol 38(8):1623\u20131629. https:\/\/doi.org\/10.3174\/ajnr.A5246","journal-title":"AJNR Am J Neuroradiol"},{"issue":"2","key":"1301_CR10","doi-asserted-by":"publisher","first-page":"512","DOI":"10.7150\/thno.64033","volume":"12","author":"HR Chen","year":"2022","unstructured":"Chen HR, Chen CW, Kuo YM, Chen B, Kuan IS, Huang H, Lee J, Anthony N, Kuan CY, Sun YY (2022) Monocytes promote acute neuroinflammation and become pathological microglia in neonatal hypoxic-ischemic brain injury. Theranostics 12(2):512\u2013529. https:\/\/doi.org\/10.7150\/thno.64033","journal-title":"Theranostics"},{"issue":"9","key":"1301_CR11","doi-asserted-by":"publisher","first-page":"a020370","DOI":"10.1101\/cshperspect.a020370","volume":"7","author":"WS Chung","year":"2015","unstructured":"Chung WS, Allen NJ, Eroglu C (2015) Astrocytes control synapse formation, function, and elimination. Cold Spring Harb Perspect Biol 7(9):a020370. https:\/\/doi.org\/10.1101\/cshperspect.a020370","journal-title":"Cold Spring Harb Perspect Biol"},{"issue":"4","key":"1301_CR12","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1017\/S1355617712000434","volume":"18","author":"US Clark","year":"2012","unstructured":"Clark US, Cohen RA, Sweet LH, Gongvatana A, Devlin KN, Hana GN, Westbrook ML, Mulligan RC, Jerskey BA, White TL, Navia B, Tashima KT (2012) Effects of HIV and early life stress on amygdala morphometry and neurocognitive function. J Int Neuropsychol Soc 18(4):657\u2013668. https:\/\/doi.org\/10.1017\/S1355617712000434","journal-title":"J Int Neuropsychol Soc"},{"issue":"1","key":"1301_CR13","doi-asserted-by":"publisher","first-page":"236","DOI":"10.1038\/s41398-022-01995-x","volume":"12","author":"YD Ding","year":"2022","unstructured":"Ding YD, Chen X, Chen ZB, Li L, Li XY, Castellanos FX, Bai TJ, Bo QJ, Cao J, Chang ZK, Chen GM, Chen NX, Chen W, Cheng C, Cheng YQ, Cui XL, Duan J, Fang YR, Gong QY, Guo WB (2022) Reduced nucleus accumbens functional connectivity in reward network and default mode network in patients with recurrent major depressive disorder. Transl Psychiatry 12(1):236. https:\/\/doi.org\/10.1038\/s41398-022-01995-x","journal-title":"Transl Psychiatry"},{"key":"1301_CR14","doi-asserted-by":"crossref","unstructured":"Evans AC, Collins DL, Mills SR, Brown ED, Kelly RL, Peters TM (1993) 3D statistical neuroanatomical models from 305 MRI volumes. In: 1993 IEEE Conference Record Nuclear Science Symposium and Medical Imaging Conference 1993, vol 1813, pp 1813\u20131817","DOI":"10.1109\/NSSMIC.1993.373602"},{"key":"1301_CR15","doi-asserted-by":"crossref","unstructured":"Ezama L, Hernandez-Cabrera JA, Seoane S, Pereda E, Janssen N (2021) Functional connectivity of the hippocampus and its subfields in resting-state networks. Eur J Neurosci 53:3378\u20133393","DOI":"10.1111\/ejn.15213"},{"issue":"4","key":"1301_CR16","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1007\/s11904-008-0029-x","volume":"5","author":"J Foley","year":"2008","unstructured":"Foley J, Ettenhofer M, Wright M, Hinkin CH (2008) Emerging issues in the neuropsychology of HIV infection. Curr HIV\/AIDS Rep 5(4):204\u2013211. https:\/\/doi.org\/10.1007\/s11904-008-0029-x","journal-title":"Curr HIV\/AIDS Rep"},{"key":"1301_CR17","doi-asserted-by":"crossref","unstructured":"Friston KJ, Holmes AP, Worsley KJ, Poline J-P, Frith CD, Frackowiak RSJ (1994) Statistical parametric maps in functional imaging: a general linear approach. Hum Brain Mapp 2:189\u2013210","DOI":"10.1002\/hbm.460020402"},{"issue":"6","key":"1301_CR18","doi-asserted-by":"publisher","first-page":"552","DOI":"10.1016\/j.jaac.2009.12.023","volume":"49","author":"W Groen","year":"2010","unstructured":"Groen W, Teluij M, Buitelaar J, Tendolkar I (2010) Amygdala and hippocampus enlargement during adolescence in autism. J Am Acad Child Adolesc Psychiatry 49(6):552\u2013560. https:\/\/doi.org\/10.1016\/j.jaac.2009.12.023","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"1301_CR19","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2024.1505440","volume":"11","author":"J Haorah","year":"2024","unstructured":"Haorah J, Malaroviyam S, Iyappan H, Samikkannu T (2024) Neurological impact of HIV\/AIDS and substance use alters brain function and structure. Front Med Lausanne 11:1505440. https:\/\/doi.org\/10.3389\/fmed.2024.1505440","journal-title":"Front Med Lausanne"},{"issue":"3","key":"1301_CR20","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1017\/S1355617704102130","volume":"10","author":"RK Heaton","year":"2004","unstructured":"Heaton RK, Marcotte TD, Mindt MR, Sadek J, Moore DJ, Bentley H, McCutchan JA, Reicks C, Grant I, Group H (2004) The impact of HIV-associated neuropsychological impairment on everyday functioning. J Int Neuropsychol Soc 10(3):317\u2013331. https:\/\/doi.org\/10.1017\/S1355617704102130","journal-title":"J Int Neuropsychol Soc"},{"issue":"37","key":"1301_CR21","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000001417","volume":"94","author":"MM Herting","year":"2015","unstructured":"Herting MM, Uban KA, Williams PL, Gautam P, Huo Y, Malee K, Yogev R, Csernansky J, Wang L, Nichols S, Van Dyke R, Sowell ER (2015) Default mode connectivity in youth with perinatally acquired HIV. Medicine Baltimore 94(37):e1417. https:\/\/doi.org\/10.1097\/MD.0000000000001417","journal-title":"Medicine Baltimore"},{"issue":"4","key":"1301_CR22","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0017463","volume":"6","author":"W Huijbers","year":"2011","unstructured":"Huijbers W, Pennartz CM, Cabeza R, Daselaar SM (2011) The hippocampus is coupled with the default network during memory retrieval but not during memory encoding. PLoS One 6(4):e17463. https:\/\/doi.org\/10.1371\/journal.pone.0017463","journal-title":"PLoS One"},{"key":"1301_CR23","doi-asserted-by":"publisher","first-page":"164","DOI":"10.3389\/fpsyt.2018.00164","volume":"9","author":"YH Jung","year":"2018","unstructured":"Jung YH, Shin JE, Lee YI, Jang JH, Jo HJ, Choi SH (2018) Altered amygdala resting-state functional connectivity and hemispheric asymmetry in patients with social anxiety disorder. Front Psychiatry 9:164. https:\/\/doi.org\/10.3389\/fpsyt.2018.00164","journal-title":"Front Psychiatry"},{"key":"1301_CR24","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1101\/sqb.2018.83.037457","volume":"83","author":"AM Klawonn","year":"2018","unstructured":"Klawonn AM, Malenka RC (2018) Nucleus accumbens modulation in reward and aversion. Cold Spring Harb Symp Quant Biol 83:119\u2013129. https:\/\/doi.org\/10.1101\/sqb.2018.83.037457","journal-title":"Cold Spring Harb Symp Quant Biol"},{"issue":"17","key":"1301_CR25","doi-asserted-by":"publisher","first-page":"1655","DOI":"10.1097\/WNR.0b013e328311d374","volume":"19","author":"AD Klunder","year":"2008","unstructured":"Klunder AD, Chiang MC, Dutton RA, Lee SE, Toga AW, Lopez OL, Aizenstein HJ, Becker JT, Thompson PM (2008) Mapping cerebellar degeneration in HIV\/AIDS. Neuroreport 19(17):1655\u20131659. https:\/\/doi.org\/10.1097\/WNR.0b013e328311d374","journal-title":"Neuroreport"},{"key":"1301_CR26","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2023.105171","volume":"149","author":"ES Kruithof","year":"2023","unstructured":"Kruithof ES, Klaus J, Schutter D (2023) The human cerebellum in reward anticipation and outcome processing: an activation likelihood estimation meta-analysis. Neurosci Biobehav Rev 149:105171. https:\/\/doi.org\/10.1016\/j.neubiorev.2023.105171","journal-title":"Neurosci Biobehav Rev"},{"key":"1301_CR27","doi-asserted-by":"publisher","first-page":"601063","DOI":"10.3389\/fnins.2020.601063","volume":"14","author":"D Liu","year":"2020","unstructured":"Liu D, Zhao C, Wang W, Wang Y, Li R, Sun J, Liu J, Liu M, Zhang X, Liang Y, Li H (2020) Altered gray matter volume and functional connectivity in human immunodeficiency virus-infected adults. Front Neurosci 14:601063. https:\/\/doi.org\/10.3389\/fnins.2020.601063","journal-title":"Front Neurosci"},{"key":"1301_CR28","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2021.757374","volume":"12","author":"Q Ma","year":"2021","unstructured":"Ma Q, Shi X, Chen G, Song F, Liu F, Zheng H, Shi Y, Cai DC (2021) HIV-associated structural and functional brain alterations in homosexual males. Front Neurol 12:757374. https:\/\/doi.org\/10.3389\/fneur.2021.757374","journal-title":"Front Neurol"},{"issue":"19","key":"1301_CR29","doi-asserted-by":"publisher","first-page":"1661","DOI":"10.1212\/WNL.0b013e3181a55f65","volume":"72","author":"PM Maki","year":"2009","unstructured":"Maki PM, Cohen MH, Weber K, Little DM, Fornelli D, Rubin LH, Perschler P, Gould F, Martin E (2009) Impairments in memory and hippocampal function in HIV-positive vs HIV-negative women: a preliminary study. Neurology 72(19):1661\u20131668. https:\/\/doi.org\/10.1212\/WNL.0b013e3181a55f65","journal-title":"Neurology"},{"key":"1301_CR30","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbih.2024.100844","volume":"41","author":"R McIntosh","year":"2024","unstructured":"McIntosh R, Lobo J, Szeto A, Hidalgo M, Kolber M (2024) Medial prefrontal cortex connectivity with the nucleus accumbens is related to HIV serostatus, perceptions of psychological stress, and monocyte expression of TNF-a. Brain, Behavior, & Immunity - Health 41:100844. https:\/\/doi.org\/10.1016\/j.bbih.2024.100844","journal-title":"Brain, Behavior, & Immunity - Health"},{"issue":"1","key":"1301_CR31","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1017\/s0033291799001567","volume":"30","author":"E Mervaala","year":"2000","unstructured":"Mervaala E, Fohr J, Kononen M, Valkonen-Korhonen M, Vainio P, Partanen K, Partanen J, Tiihonen J, Viinamaki H, Karjalainen AK, Lehtonen J (2000) Quantitative MRI of the hippocampus and amygdala in severe depression. Psychol Med 30(1):117\u2013125. https:\/\/doi.org\/10.1017\/s0033291799001567","journal-title":"Psychol Med"},{"issue":"4","key":"1301_CR32","doi-asserted-by":"publisher","first-page":"796","DOI":"10.1111\/jon.12861","volume":"31","author":"S Minosse","year":"2021","unstructured":"Minosse S, Picchi E, Di Giuliano F, Sarmati L, Teti E, Pistolese CA, Lanzafame S, Di Cio F, Guerrisi M, Andreoni M, Floris R, Toschi N, Garaci F (2021) Functional brain network reorganization in HIV infection. J Neuroimaging 31(4):796\u2013808. https:\/\/doi.org\/10.1111\/jon.12861","journal-title":"J Neuroimaging"},{"issue":"1","key":"1301_CR33","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1002\/aur.227","volume":"5","author":"CM Murphy","year":"2012","unstructured":"Murphy CM, Deeley Q, Daly EM, Ecker C, O\u2019Brien FM, Hallahan B, Loth E, Toal F, Reed S, Hales S, Robertson DM, Craig MC, Mullins D, Barker GJ, Lavender T, Johnston P, Murphy KC, Murphy DG (2012) Anatomy and aging of the amygdala and hippocampus in autism spectrum disorder: an in vivo magnetic resonance imaging study of Asperger syndrome. Autism Res 5(1):3\u201312. https:\/\/doi.org\/10.1002\/aur.227","journal-title":"Autism Res"},{"key":"1301_CR34","doi-asserted-by":"publisher","first-page":"804774","DOI":"10.3389\/fnins.2022.804774","volume":"16","author":"SR Nass","year":"2022","unstructured":"Nass SR, Ohene-Nyako M, Hahn YK, Knapp PE, Hauser KF (2022) Neurodegeneration within the amygdala is differentially induced by opioid and HIV-1 Tat exposure. Front Neurosci 16:804774. https:\/\/doi.org\/10.3389\/fnins.2022.804774","journal-title":"Front Neurosci"},{"key":"1301_CR35","doi-asserted-by":"publisher","first-page":"102283","DOI":"10.1016\/j.pneurobio.2022.102283","volume":"214","author":"S Ocklenburg","year":"2022","unstructured":"Ocklenburg S, Peterburs J, Mundorf A (2022) Hemispheric asymmetries in the amygdala: A comparative primer. Prog Neurobiol 214:102283. https:\/\/doi.org\/10.1016\/j.pneurobio.2022.102283","journal-title":"Prog Neurobiol"},{"issue":"9","key":"1301_CR36","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1016\/j.tins.2020.06.007","volume":"43","author":"O Osborne","year":"2020","unstructured":"Osborne O, Peyravian N, Nair M, Toborek M (2020) The paradox of HIV Blood\u2013Brain barrier penetrance and antiretroviral drug delivery deficiencies. Trends Neurosci 43(9):695\u2013708. https:\/\/doi.org\/10.1016\/j.tins.2020.06.007","journal-title":"Trends Neurosci"},{"key":"1301_CR37","doi-asserted-by":"publisher","unstructured":"Pimentel E, Sivalingam K, Doke M, Samikkannu T (2020) Effects of Drugs of Abuse on the Blood-Brain Barrier: A Brief Overview. Front Neurosci, 14(513). https:\/\/doi.org\/10.3389\/fnins.2020.00513. PMID: 32670001","DOI":"10.3389\/fnins.2020.00513"},{"issue":"2","key":"1301_CR38","first-page":"435","volume":"40","author":"DJ Plummer","year":"1999","unstructured":"Plummer DJ, Marcotte TD, Sample PA, Wolfson T, Heaton RK, Grant I, Freeman WR (1999) Neuropsychological impairment-associated visual field deficits in HIV infection. HNRC Group. HIV neurobehavioral research center. Invest Ophthalmol Vis Sci 40(2):435\u2013442. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/9950603","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"1","key":"1301_CR39","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1080\/15504263.2018.1526432","volume":"15","author":"S Potvin","year":"2019","unstructured":"Potvin S, Dugre JR, Fahim C, Dumais A (2019) Increased connectivity between the nucleus accumbens and the default mode network in patients with schizophrenia during cigarette cravings. J Dual Diagn 15(1):8\u201315. https:\/\/doi.org\/10.1080\/15504263.2018.1526432","journal-title":"J Dual Diagn"},{"key":"1301_CR40","doi-asserted-by":"crossref","unstructured":"Rayhan RU, Stevens BW, Raksit MP, Ripple JA, Timbol CR, Adewuyi O, VanMeter JW, Baraniuk JN (2013) Exercise challenge in Gulf War Illness reveals two subgroups with altered brain structure and function. PLoS One 8: e63903","DOI":"10.1371\/journal.pone.0063903"},{"issue":"45","key":"1301_CR41","doi-asserted-by":"publisher","first-page":"7554","DOI":"10.1523\/JNEUROSCI.1451-23.2023","volume":"43","author":"S Rudolph","year":"2023","unstructured":"Rudolph S, Badura A, Lutzu S, Pathak SS, Thieme A, Verpeut JL, Wagner MJ, Yang YM, Fioravante D (2023) Cognitive-Affective functions of the cerebellum. J Neurosci 43(45):7554\u20137564. https:\/\/doi.org\/10.1523\/JNEUROSCI.1451-23.2023","journal-title":"J Neurosci"},{"key":"1301_CR42","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1016\/j.nicl.2018.07.024","volume":"20","author":"V Samboju","year":"2018","unstructured":"Samboju V, Philippi CL, Chan P, Cobigo Y, Fletcher JLK, Robb M, Hellmuth J, Benjapornpong K, Dumrongpisutikul N, Pothisri M, Paul R, Ananworanich J, Spudich S, Valcour V, Search RV, teams RV p (2018) Structural and functional brain imaging in acute HIV. Neuroimage Clin 20:327\u2013335. https:\/\/doi.org\/10.1016\/j.nicl.2018.07.024","journal-title":"Neuroimage Clin"},{"issue":"Pt 4","key":"1301_CR43","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1093\/brain\/121.4.561","volume":"121","author":"JD Schmahmann","year":"1998","unstructured":"Schmahmann JD, Sherman JC (1998) The cerebellar cognitive affective syndrome. Brain 121(Pt 4):561\u2013579. https:\/\/doi.org\/10.1093\/brain\/121.4.561","journal-title":"Brain"},{"issue":"1","key":"1301_CR44","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1016\/j.schres.2010.08.023","volume":"125","author":"I Spoletini","year":"2011","unstructured":"Spoletini I, Piras F, Fagioli S, Rubino IA, Martinotti G, Siracusano A, Caltagirone C, Spalletta G (2011) Suicidal attempts and increased right amygdala volume in schizophrenia. Schizophr Res 125(1):30\u201340. https:\/\/doi.org\/10.1016\/j.schres.2010.08.023","journal-title":"Schizophr Res"},{"issue":"4","key":"1301_CR45","doi-asserted-by":"publisher","first-page":"826","DOI":"10.1038\/sj.npp.1300399","volume":"29","author":"PR Szeszko","year":"2004","unstructured":"Szeszko PR, MacMillan S, McMeniman M, Lorch E, Madden R, Ivey J, Banerjee SP, Moore GJ, Rosenberg DR (2004) Amygdala volume reductions in pediatric patients with obsessive-compulsive disorder treated with paroxetine: preliminary findings. Neuropsychopharmacology 29(4):826\u2013832. https:\/\/doi.org\/10.1038\/sj.npp.1300399","journal-title":"Neuropsychopharmacology"},{"issue":"13","key":"1301_CR46","doi-asserted-by":"publisher","first-page":"1186","DOI":"10.1212\/WNL.0b013e318288792b","volume":"80","author":"JB Thomas","year":"2013","unstructured":"Thomas JB, Brier MR, Snyder AZ, Vaida FF, Ances BM (2013) Pathways to neurodegeneration: effects of HIV and aging on resting-state functional connectivity. Neurology 80(13):1186\u20131193. https:\/\/doi.org\/10.1212\/WNL.0b013e318288792b","journal-title":"Neurology"},{"issue":"11","key":"1301_CR47","doi-asserted-by":"publisher","DOI":"10.4172\/2155-6113.1000255","volume":"4","author":"H Ton","year":"2013","unstructured":"Ton H, Xiong H (2013) Astrocyte dysfunctions and HIV-1 neurotoxicity. J AIDS Clin Res 4(11):255. https:\/\/doi.org\/10.4172\/2155-6113.1000255","journal-title":"J AIDS Clin Res"},{"key":"1301_CR48","doi-asserted-by":"publisher","first-page":"362","DOI":"10.3389\/fcimb.2019.00362","volume":"9","author":"C Wallet","year":"2019","unstructured":"Wallet C, De Rovere M, Van Assche J, Daouad F, De Wit S, Gautier V, Mallon PWG, Marcello A, Van Lint C, Rohr O, Schwartz C (2019) Microglial cells: the main HIV-1 reservoir in the brain. Front Cell Infect Microbiol 9:362. https:\/\/doi.org\/10.3389\/fcimb.2019.00362","journal-title":"Front Cell Infect Microbiol"},{"issue":"12","key":"1301_CR49","doi-asserted-by":"publisher","first-page":"1465","DOI":"10.1177\/0963689719878380","volume":"28","author":"SC Wang","year":"2019","unstructured":"Wang SC, Maher B (2019) Substance use disorder, intravenous injection, and HIV infection: a review. Cell Transpl 28(12):1465\u20131471. https:\/\/doi.org\/10.1177\/0963689719878380","journal-title":"Cell Transpl"},{"issue":"3","key":"1301_CR50","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1007\/s11481-008-9110-x","volume":"3","author":"T Wang","year":"2008","unstructured":"Wang T, Gong N, Liu J, Kadiu I, Kraft-Terry SD, Schlautman JD, Ciborowski P, Volsky DJ, Gendelman HE (2008) HIV-1-infected astrocytes and the microglial proteome. J Neuroimmune Pharmacol 3(3):173\u2013186. https:\/\/doi.org\/10.1007\/s11481-008-9110-x","journal-title":"J Neuroimmune Pharmacol"},{"key":"1301_CR51","doi-asserted-by":"crossref","unstructured":"Whitfield-Gabrieli S, Nieto-Castanon A (2012) Conn: a functional connectivity toolbox for correlated and anticorrelated brain networks. Brain Connect 2:125\u2013141","DOI":"10.1089\/brain.2012.0073"},{"issue":"6","key":"1301_CR52","doi-asserted-by":"publisher","first-page":"651","DOI":"10.1002\/ana.410290613","volume":"29","author":"CA Wiley","year":"1991","unstructured":"Wiley CA, Masliah E, Morey M, Lemere C, DeTeresa R, Grafe M, Hansen L, Terry R (1991) Neocortical damage during HIV infection. Ann Neurol 29(6):651\u2013657. https:\/\/doi.org\/10.1002\/ana.410290613","journal-title":"Ann Neurol"},{"issue":"3","key":"1301_CR53","doi-asserted-by":"publisher","first-page":"897","DOI":"10.1002\/hbm.22674","volume":"36","author":"TW Wilson","year":"2015","unstructured":"Wilson TW, Heinrichs-Graham E, Becker KM, Aloi J, Robertson KR, Sandkovsky U, White ML, O\u2019Neill J, Knott NL, Fox HS, Swindells S (2015) Multimodal neuroimaging evidence of alterations in cortical structure and function in HIV-infected older adults. Hum Brain Mapp 36(3):897\u2013910. https:\/\/doi.org\/10.1002\/hbm.22674","journal-title":"Hum Brain Mapp"},{"key":"1301_CR54","doi-asserted-by":"publisher","DOI":"10.1016\/j.nicl.2021.102677","volume":"30","author":"FN Yang","year":"2021","unstructured":"Yang FN, Hassanzadeh-Behbahani S, Bronshteyn M, Dawson M, Kumar P, Moore DJ, Ellis RJ, Jiang X (2021) Connectome-based prediction of global cognitive performance in people with HIV. Neuroimage Clin 30:102677. https:\/\/doi.org\/10.1016\/j.nicl.2021.102677","journal-title":"Neuroimage Clin"},{"issue":"5","key":"1301_CR55","doi-asserted-by":"publisher","first-page":"704","DOI":"10.1007\/s13365-017-0553-9","volume":"23","author":"Y Zhuang","year":"2017","unstructured":"Zhuang Y, Qiu X, Wang L, Ma Q, Mapstone M, Luque A, Weber M, Tivarus M, Miller E, Arduino RC, Zhong J, Schifitto G (2017) Combination antiretroviral therapy improves cognitive performance and functional connectivity in treatment-naive HIV-infected individuals. J Neurovirol 23(5):704\u2013712. https:\/\/doi.org\/10.1007\/s13365-017-0553-9","journal-title":"J Neurovirol"}],"container-title":["Journal of NeuroVirology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13365-025-01301-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s13365-025-01301-7","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13365-025-01301-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:01:26Z","timestamp":1772118086000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s13365-025-01301-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,26]]},"references-count":55,"alternative-id":["1301"],"URL":"https:\/\/doi.org\/10.1007\/s13365-025-01301-7","relation":{},"ISSN":["1355-0284","1538-2443"],"issn-type":[{"value":"1355-0284","type":"print"},{"value":"1538-2443","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,26]]},"assertion":[{"value":"11 August 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 December 2025","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 December 2025","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 February 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}