{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T15:45:07Z","timestamp":1787499907295,"version":"build-2736575974"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2023,12,15]],"date-time":"2023-12-15T00:00:00Z","timestamp":1702598400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,12,15]],"date-time":"2023-12-15T00:00:00Z","timestamp":1702598400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["Nos.82073326"],"award-info":[{"award-number":["Nos.82073326"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["Nos.82073326"],"award-info":[{"award-number":["Nos.82073326"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["Nos.82073326"],"award-info":[{"award-number":["Nos.82073326"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["Nos.82073326"],"award-info":[{"award-number":["Nos.82073326"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["Nos.82073326"],"award-info":[{"award-number":["Nos.82073326"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["Nos.82073326"],"award-info":[{"award-number":["Nos.82073326"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["Nos.82073326"],"award-info":[{"award-number":["Nos.82073326"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["Nos.82073326"],"award-info":[{"award-number":["Nos.82073326"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Shanghai Sailing Program","award":["No.22YF1426200"],"award-info":[{"award-number":["No.22YF1426200"]}]},{"name":"Shanghai Sailing Program","award":["No.22YF1426200"],"award-info":[{"award-number":["No.22YF1426200"]}]},{"name":"Shanghai Sailing Program","award":["No.22YF1426200"],"award-info":[{"award-number":["No.22YF1426200"]}]},{"name":"Shanghai Sailing Program","award":["No.22YF1426200"],"award-info":[{"award-number":["No.22YF1426200"]}]},{"name":"Shanghai Sailing Program","award":["No.22YF1426200"],"award-info":[{"award-number":["No.22YF1426200"]}]},{"name":"Shanghai Sailing Program","award":["No.22YF1426200"],"award-info":[{"award-number":["No.22YF1426200"]}]},{"name":"Shanghai Sailing Program","award":["No.22YF1426200"],"award-info":[{"award-number":["No.22YF1426200"]}]},{"name":"Shanghai Sailing Program","award":["No.22YF1426200"],"award-info":[{"award-number":["No.22YF1426200"]}]},{"name":"Shanghai Sailing Program","award":["No.22YF1426200"],"award-info":[{"award-number":["No.22YF1426200"]}]},{"name":"Jiaotong University Medical-Engineering Cross Fund","award":["No. YG2022QN007"],"award-info":[{"award-number":["No. YG2022QN007"]}]},{"name":"Jiaotong University Medical-Engineering Cross Fund","award":["No. YG2022QN007"],"award-info":[{"award-number":["No. YG2022QN007"]}]},{"name":"Jiaotong University Medical-Engineering Cross Fund","award":["No. YG2022QN007"],"award-info":[{"award-number":["No. YG2022QN007"]}]},{"name":"Jiaotong University Medical-Engineering Cross Fund","award":["No. YG2022QN007"],"award-info":[{"award-number":["No. YG2022QN007"]}]},{"name":"Jiaotong University Medical-Engineering Cross Fund","award":["No. YG2022QN007"],"award-info":[{"award-number":["No. YG2022QN007"]}]},{"name":"Jiaotong University Medical-Engineering Cross Fund","award":["No. YG2022QN007"],"award-info":[{"award-number":["No. YG2022QN007"]}]},{"name":"Jiaotong University Medical-Engineering Cross Fund","award":["No. YG2022QN007"],"award-info":[{"award-number":["No. YG2022QN007"]}]},{"name":"Jiaotong University Medical-Engineering Cross Fund","award":["No. YG2022QN007"],"award-info":[{"award-number":["No. YG2022QN007"]}]},{"name":"Jiaotong University Medical-Engineering Cross Fund","award":["No. YG2022QN007"],"award-info":[{"award-number":["No. YG2022QN007"]}]},{"name":"Jiaotong University Medical-Engineering Cross Fund","award":["No. YG2022QN007"],"award-info":[{"award-number":["No. YG2022QN007"]}]},{"name":"Shenkang enter city hospital emerging frontier technology joint research project","award":["No. SHDC12020121"],"award-info":[{"award-number":["No. SHDC12020121"]}]},{"name":"Shenkang enter city hospital emerging frontier technology joint research project","award":["No. SHDC12020121"],"award-info":[{"award-number":["No. SHDC12020121"]}]},{"name":"Shenkang enter city hospital emerging frontier technology joint research project","award":["No. SHDC12020121"],"award-info":[{"award-number":["No. SHDC12020121"]}]},{"name":"Shenkang enter city hospital emerging frontier technology joint research project","award":["No. SHDC12020121"],"award-info":[{"award-number":["No. SHDC12020121"]}]},{"name":"Shenkang enter city hospital emerging frontier technology joint research project","award":["No. SHDC12020121"],"award-info":[{"award-number":["No. SHDC12020121"]}]},{"name":"Shenkang enter city hospital emerging frontier technology joint research project","award":["No. SHDC12020121"],"award-info":[{"award-number":["No. SHDC12020121"]}]},{"name":"Shenkang enter city hospital emerging frontier technology joint research project","award":["No. SHDC12020121"],"award-info":[{"award-number":["No. SHDC12020121"]}]},{"name":"Shenkang enter city hospital emerging frontier technology joint research project","award":["No. SHDC12020121"],"award-info":[{"award-number":["No. SHDC12020121"]}]},{"name":"Shenkang enter city hospital emerging frontier technology joint research project","award":["No. SHDC12020121"],"award-info":[{"award-number":["No. SHDC12020121"]}]},{"name":"Guangci Clinical Technology Sailing Project","award":["No. YW20210033"],"award-info":[{"award-number":["No. YW20210033"]}]},{"name":"Guangci Clinical Technology Sailing Project","award":["No. YW20210033"],"award-info":[{"award-number":["No. YW20210033"]}]},{"name":"Guangci Clinical Technology Sailing Project","award":["No. YW20210033"],"award-info":[{"award-number":["No. YW20210033"]}]},{"name":"Guangci Clinical Technology Sailing Project","award":["No. YW20210033"],"award-info":[{"award-number":["No. YW20210033"]}]},{"name":"Guangci Clinical Technology Sailing Project","award":["No. YW20210033"],"award-info":[{"award-number":["No. YW20210033"]}]},{"name":"Guangci Clinical Technology Sailing Project","award":["No. YW20210033"],"award-info":[{"award-number":["No. YW20210033"]}]},{"name":"Guangci Clinical Technology Sailing Project","award":["No. YW20210033"],"award-info":[{"award-number":["No. YW20210033"]}]},{"name":"Guangci Clinical Technology Sailing Project","award":["No. YW20210033"],"award-info":[{"award-number":["No. YW20210033"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cell Oncol."],"published-print":{"date-parts":[[2024,6]]},"DOI":"10.1007\/s13402-023-00907-5","type":"journal-article","created":{"date-parts":[[2023,12,14]],"date-time":"2023-12-14T22:02:16Z","timestamp":1702591336000},"page":"939-950","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["ATF3-induced activation of NF-\u03baB pathway results in acquired PARP inhibitor resistance in pancreatic adenocarcinoma"],"prefix":"10.1007","volume":"47","author":[{"given":"Yang","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yizhi","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pengyi","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuyu","family":"Zhai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yihao","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaomei","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiayu","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minmin","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debin","family":"Qi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaxing","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youwei","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weishen","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baiyong","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,12,15]]},"reference":[{"issue":"10242","key":"907_CR1","doi-asserted-by":"publisher","first-page":"2008","DOI":"10.1016\/S0140-6736(20)30974-0","volume":"395","author":"JD Mizrahi","year":"2020","unstructured":"J.D. Mizrahi, R. Surana, J.W. Valle, R.T. Shroff, Pancreatic cancer. Lancet. 395(10242), 2008\u20132020 (2020)","journal-title":"Lancet."},{"issue":"6","key":"907_CR2","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1038\/s41575-018-0005-x","volume":"15","author":"JP Neoptolemos","year":"2018","unstructured":"J.P. Neoptolemos, J. Kleeff, P. Michl, E. Costello, W. Greenhalf, D.H. Palmer, Therapeutic developments in pancreatic cancer: current and future perspectives. Nat. Rev. Gastroenterol. Hepatol. 15(6), 333\u2013348 (2018)","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"issue":"1","key":"907_CR3","doi-asserted-by":"publisher","first-page":"7","DOI":"10.3322\/caac.21654","volume":"71","author":"RL Siegel","year":"2021","unstructured":"R.L. Siegel, K.D. Miller, H.E. Fuchs, A. Jemal, Cancer statistics, 2021. CA Cancer J. Clin. 71(1), 7\u201333 (2021)","journal-title":"CA Cancer J. Clin."},{"issue":"9","key":"907_CR4","doi-asserted-by":"publisher","first-page":"851","DOI":"10.1001\/jama.2021.13027","volume":"326","author":"W Park","year":"2021","unstructured":"W. Park, A. Chawla, E.M. O\u2019Reilly, Pancreatic cancer: a review. JAMA. 326(9), 851\u2013862 (2021)","journal-title":"JAMA."},{"issue":"9","key":"907_CR5","doi-asserted-by":"publisher","first-page":"1437","DOI":"10.1093\/annonc\/mdz192","volume":"30","author":"J Mateo","year":"2019","unstructured":"J. Mateo, C.J. Lord, V. Serra, A. Tutt, J. Balma\u00f1a, M. Castroviejo-Bermejo et al., A decade of clinical development of PARP inhibitors in perspective. Ann. Oncol. 30(9), 1437\u20131447 (2019)","journal-title":"Ann. Oncol."},{"issue":"3","key":"907_CR6","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1200\/JCO.2014.56.2728","volume":"33","author":"B Kaufman","year":"2015","unstructured":"B. Kaufman, R. Shapira-Frommer, R.K. Schmutzler, M.W. Audeh, M. Friedlander, J. Balma\u00f1a et al., Olaparib monotherapy in patients with advanced cancer and a germline BRCA1\/2 mutation. J. Clin. Oncol. 33(3), 244\u2013250 (2015)","journal-title":"J. Clin. Oncol."},{"issue":"6","key":"907_CR7","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1056\/NEJMoa1706450","volume":"377","author":"M Robson","year":"2017","unstructured":"M. Robson, S.-A. Im, E. Senkus, B. Xu, S.M. Domchek, N. Masuda et al., Olaparib for metastatic breast cancer in patients with a germline BRCA mutation. N. Engl. J. Med. 377(6), 523\u2013533 (2017)","journal-title":"N. Engl. J. Med."},{"issue":"26","key":"907_CR8","doi-asserted-by":"publisher","first-page":"2495","DOI":"10.1056\/NEJMoa1810858","volume":"379","author":"K Moore","year":"2018","unstructured":"K. Moore, N. Colombo, G. Scambia, B.-G. Kim, A. Oaknin, M. Friedlander et al., Maintenance olaparib in patients with newly diagnosed advanced ovarian cancer. N. Engl. J. Med. 379(26), 2495\u20132505 (2018)","journal-title":"N. Engl. J. Med."},{"issue":"4","key":"907_CR9","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1056\/NEJMoa1903387","volume":"381","author":"T Golan","year":"2019","unstructured":"T. Golan, P. Hammel, M. Reni, E. Van Cutsem, T. Macarulla, M.J. Hall et al., Maintenance olaparib for germline BRCA-mutated metastatic pancreatic cancer. N. Engl. J. Med. 381(4), 317\u2013327 (2019)","journal-title":"N. Engl. J. Med."},{"issue":"1","key":"907_CR10","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1186\/s12943-020-01227-0","volume":"19","author":"H Li","year":"2020","unstructured":"H. Li, Z.Y. Liu, N. Wu, Y.C. Chen, Q. Cheng, J. Wang, PARP inhibitor resistance: the underlying mechanisms and clinical implications. Mol. Cancer 19(1), 107 (2020)","journal-title":"Mol. Cancer"},{"issue":"11","key":"907_CR11","doi-asserted-by":"publisher","first-page":"1053","DOI":"10.1007\/s00109-009-0520-x","volume":"87","author":"MR Thompson","year":"2009","unstructured":"M.R. Thompson, D. Xu, B.R.G. Williams, ATF3 transcription factor and its emerging roles in immunity and cancer. J. Mol. Med. (Berl) 87(11), 1053\u20131060 (2009)","journal-title":"J. Mol. Med. (Berl)"},{"issue":"5","key":"907_CR12","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1007\/s00395-018-0698-6","volume":"113","author":"H Zhou","year":"2018","unstructured":"H. Zhou, N. Li, Y. Yuan, Y.-G. Jin, H. Guo, W. Deng et al., Activating transcription factor 3 in cardiovascular diseases: a potential therapeutic target. Basic Res. Cardiol. 113(5), 37 (2018)","journal-title":"Basic Res. Cardiol."},{"key":"907_CR13","doi-asserted-by":"publisher","first-page":"556","DOI":"10.3389\/fendo.2020.00556","volume":"11","author":"H-C Ku","year":"2020","unstructured":"H.-C. Ku, C.-F. Cheng, Master regulator activating transcription factor 3 (ATF3) in metabolic homeostasis and cancer. Front. Endocrinol. (Lausanne). 11, 556 (2020)","journal-title":"Front. Endocrinol. (Lausanne)."},{"issue":"7","key":"907_CR14","doi-asserted-by":"publisher","first-page":"1423","DOI":"10.1210\/me.2009-0463","volume":"24","author":"EJ Zmuda","year":"2010","unstructured":"E.J. Zmuda, L. Qi, M.X. Zhu, R.G. Mirmira, M.R. Montminy, T. Hai, The roles of ATF3, an adaptive-response gene, in high-fat-diet-induced diabetes and pancreatic beta-cell dysfunction. Mol. Endocrinol. 24(7), 1423\u20131433 (2010)","journal-title":"Mol. Endocrinol."},{"issue":"17","key":"907_CR15","doi-asserted-by":"publisher","first-page":"3118","DOI":"10.1038\/s41388-021-01771-z","volume":"40","author":"N Azizi","year":"2021","unstructured":"N. Azizi, J. Toma, M. Martin, M.F. Khalid, F. Mousavi, P.W. Win et al., Loss of activating transcription factor 3 prevents KRAS-mediated pancreatic cancer. Oncogene 40(17), 3118\u20133135 (2021)","journal-title":"Oncogene"},{"key":"907_CR16","doi-asserted-by":"crossref","unstructured":"J. Kuroda, M. Yamamoto, H. Nagoshi, T. Kobayashi, N. Sasaki, Y. Shimura, et al., Targeting activating transcription factor 3 by Galectin-9 induces apoptosis and overcomes various types of treatment resistance in chronic myelogenous leukemia. Mol. Cancer Res. 8(7), 994\u20131001 (2010)","DOI":"10.1158\/1541-7786.MCR-10-0040"},{"key":"907_CR17","doi-asserted-by":"crossref","unstructured":"S. Borgoni, E. Sofyal\u0131, M. Soleimani, H. Wilhelm, K. M\u00fcller-Decker, R. Will, et al., Time-resolved profiling reveals ATF3 as a novel mediator of endocrine resistance in breast cancer. Cancers. 12(10) (2020)","DOI":"10.3390\/cancers12102918"},{"issue":"7182","key":"907_CR18","doi-asserted-by":"publisher","first-page":"1111","DOI":"10.1038\/nature06548","volume":"451","author":"SL Edwards","year":"2008","unstructured":"S.L. Edwards, R. Brough, C.J. Lord, R. Natrajan, R. Vatcheva, D.A. Levine et al., Resistance to therapy caused by intragenic deletion in BRCA2. Nature 451(7182), 1111\u20131115 (2008)","journal-title":"Nature"},{"issue":"1","key":"907_CR19","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1080\/15384047.2021.2024414","volume":"23","author":"N Guo","year":"2022","unstructured":"N. Guo, M.Z. Li, L.M. Wang, H.D. Chen, S.S. Song, Z.H. Miao et al., Repeated treatments of Capan-1 cells with PARP1 and Chk1 inhibitors promote drug resistance, migration and invasion. Cancer Biol. Ther. 23(1), 69\u201382 (2022)","journal-title":"Cancer Biol. Ther."},{"issue":"15","key":"907_CR20","doi-asserted-by":"publisher","first-page":"1769","DOI":"10.1038\/onc.2009.29","volume":"28","author":"A Wicovsky","year":"2009","unstructured":"A. Wicovsky, F. Henkler, S. Salzmann, P. Scheurich, C. Kneitz, H. Wajant, Tumor necrosis factor receptor-associated factor-1 enhances proinflammatory TNF receptor-2 signaling and modifies TNFR1\u2013TNFR2 cooperation. Oncogene 28(15), 1769\u20131781 (2009)","journal-title":"Oncogene"},{"key":"907_CR21","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.semcancer.2016.07.003","volume":"39","author":"M-Q Du","year":"2016","unstructured":"M.-Q. Du, MALT lymphoma: a paradigm of NF-\u03baB dysregulation. Semin. Cancer Biol. 39, 49\u201360 (2016)","journal-title":"Semin. Cancer Biol."},{"issue":"9","key":"907_CR22","doi-asserted-by":"publisher","first-page":"2367","DOI":"10.1016\/j.celrep.2016.10.077","volume":"17","author":"SF Johnson","year":"2016","unstructured":"S.F. Johnson, C. Cruz, A.K. Greifenberg, S. Dust, D.G. Stover, D. Chi et al., CDK12 inhibition reverses de novo and acquired PARP inhibitor resistance in BRCA wild-type and mutated models of triple-negative breast cancer. Cell Rep. 17(9), 2367\u20132381 (2016)","journal-title":"Cell Rep."},{"issue":"1","key":"907_CR23","doi-asserted-by":"publisher","first-page":"3970","DOI":"10.1038\/s41467-018-05564-z","volume":"9","author":"O Kondrashova","year":"2018","unstructured":"O. Kondrashova, M. Topp, K. Nesic, E. Lieschke, G.-Y. Ho, M.I. Harrell et al., Methylation of all BRCA1 copies predicts response to the PARP inhibitor rucaparib in ovarian carcinoma. Nat. Commun. 9(1), 3970 (2018)","journal-title":"Nat. Commun."},{"issue":"24","key":"907_CR24","doi-asserted-by":"publisher","first-page":"11983","DOI":"10.1158\/0008-5472.CAN-06-0943","volume":"66","author":"S Bandyopadhyay","year":"2006","unstructured":"S. Bandyopadhyay, Y. Wang, R. Zhan, S.K. Pai, M. Watabe, M. Iiizumi et al., The tumor metastasis suppressor gene Drg-1 down-regulates the expression of activating transcription factor 3 in prostate cancer. Can. Res. 66(24), 11983\u201311990 (2006)","journal-title":"Can. Res."},{"issue":"2","key":"907_CR25","doi-asserted-by":"publisher","first-page":"408","DOI":"10.1002\/jcb.22267","volume":"108","author":"S Kwok","year":"2009","unstructured":"S. Kwok, S.R. Rittling, N.C. Partridge, C.S. Benson, M. Thiyagaraj, N. Srinivasan et al., Transforming growth factor-\u03b21 regulation of ATF-3 and identification of ATF-3 target genes in breast cancer cells. J. Cell. Biochem. 108(2), 408\u2013414 (2009)","journal-title":"J. Cell. Biochem."},{"issue":"34","key":"907_CR26","doi-asserted-by":"publisher","first-page":"E7159","DOI":"10.1073\/pnas.1700455114","volume":"114","author":"YS Chang","year":"2017","unstructured":"Y.S. Chang, S.P. Jalgaonkar, J.D. Middleton, T. Hai, Stress-inducible gene Atf3 in the noncancer host cells contributes to chemotherapy-exacerbated breast cancer metastasis. Proc. Natl. Acad. Sci. 114(34), E7159\u2013E7168 (2017)","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"10","key":"907_CR27","doi-asserted-by":"publisher","first-page":"4664","DOI":"10.1111\/jcmm.13688","volume":"22","author":"W Zhao","year":"2018","unstructured":"W. Zhao, M. Sun, S. Li, Z. Chen, D. Geng, Transcription factor ATF3 mediates the radioresistance of breast cancer. J. Cell. Mol. Med. 22(10), 4664\u20134675 (2018)","journal-title":"J. Cell. Mol. Med."},{"issue":"1","key":"907_CR28","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1186\/s11658-021-00271-y","volume":"26","author":"D Fu","year":"2021","unstructured":"D. Fu, C. Wang, L. Yu, R. Yu, Induction of ferroptosis by ATF3 elevation alleviates cisplatin resistance in gastric cancer by restraining Nrf2\/Keap1\/xCT signaling. Cell. Mol. Biol. Lett. 26(1), 26 (2021)","journal-title":"Cell. Mol. Biol. Lett."},{"issue":"18","key":"907_CR29","doi-asserted-by":"publisher","first-page":"5573","DOI":"10.1158\/1078-0432.CCR-17-0466","volume":"23","author":"AC Ch\u00fceh","year":"2017","unstructured":"A.C. Ch\u00fceh, J.W.T. Tse, M. Dickinson, P. Ioannidis, L. Jenkins, L. Togel et al., ATF3 repression of BCL-X determines apoptotic sensitivity to HDAC inhibitors across tumor types. Clin. Cancer Res. 23(18), 5573\u20135584 (2017)","journal-title":"Clin. Cancer Res."},{"issue":"19","key":"907_CR30","doi-asserted-by":"publisher","first-page":"5119","DOI":"10.1158\/0008-5472.CAN-12-1842","volume":"72","author":"YH Jan","year":"2012","unstructured":"Y.H. Jan, H.Y. Tsai, C.J. Yang, M.S. Huang, Y.F. Yang, T.C. Lai et al., Adenylate kinase-4 is a marker of poor clinical outcomes that promotes metastasis of lung cancer by downregulating the transcription factor ATF3. Can. Res. 72(19), 5119\u20135129 (2012)","journal-title":"Can. Res."},{"key":"907_CR31","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2020.554502","volume":"11","author":"J-H Zhu","year":"2020","unstructured":"J.-H. Zhu, Q.-L. Yan, J.-W. Wang, Y. Chen, Q.-H. Ye, Z.-J. Wang et al., The key genes for perineural invasion in pancreatic ductal adenocarcinoma identified with Monte-Carlo feature selection method. Front. Genet. 11, 554502 (2020)","journal-title":"Front. Genet."},{"issue":"18","key":"907_CR32","doi-asserted-by":"publisher","first-page":"5298","DOI":"10.7150\/thno.34559","volume":"9","author":"Z Zeng","year":"2019","unstructured":"Z. Zeng, F.Y. Xu, H. Zheng, P. Cheng, Q.Y. Chen, Z. Ye et al., LncRNA-MTA2TR functions as a promoter in pancreatic cancer via driving deacetylation-dependent accumulation of HIF-1\u03b1. Theranostics. 9(18), 5298\u20135314 (2019)","journal-title":"Theranostics."},{"key":"907_CR33","doi-asserted-by":"publisher","first-page":"310","DOI":"10.1016\/j.ijbiomac.2018.08.107","volume":"120","author":"M Rohini","year":"2018","unstructured":"M. Rohini, A. Haritha Menon, N. Selvamurugan, Role of activating transcription factor 3 and its interacting proteins under physiological and pathological conditions. Int. J. Biol. Macromol. 120, 310\u2013317 (2018)","journal-title":"Int. J. Biol. Macromol."},{"issue":"1","key":"907_CR34","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1186\/s12964-020-00576-z","volume":"18","author":"Y Liang","year":"2020","unstructured":"Y. Liang, Y. Jiang, X. Jin, P. Chen, Y. Heng, L. Cai et al., Neddylation inhibition activates the protective autophagy through NF-\u03baB-catalase-ATF3 Axis in human esophageal cancer cells. Cell Commun. Signal 18(1), 72 (2020)","journal-title":"Cell Commun. Signal"},{"key":"907_CR35","doi-asserted-by":"publisher","first-page":"954","DOI":"10.1016\/j.ijbiomac.2019.05.062","volume":"134","author":"M Rohini","year":"2019","unstructured":"M. Rohini, B. Arumugam, M. Vairamani, N. Selvamurugan, Stimulation of ATF3 interaction with Smad4 via TGF-\u03b21 for matrix metalloproteinase 13 gene activation in human breast cancer cells. Int. J. Biol. Macromol. 134, 954\u2013961 (2019)","journal-title":"Int. J. Biol. Macromol."},{"issue":"14","key":"907_CR36","doi-asserted-by":"publisher","first-page":"2590","DOI":"10.1038\/sj.emboj.7600742","volume":"24","author":"K Tamura","year":"2005","unstructured":"K. Tamura, B. Hua, S. Adachi, I. Guney, J. Kawauchi, M. Morioka et al., Stress response gene ATF3 is a target of c-myc in serum-induced cell proliferation. EMBO J. 24(14), 2590\u20132601 (2005)","journal-title":"EMBO J."},{"issue":"3","key":"907_CR37","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1016\/j.dnarep.2007.12.004","volume":"7","author":"M Hamdi","year":"2008","unstructured":"M. Hamdi, H.E. Popeijus, F. Carlotti, J.M. Janssen, C. van der Burgt, P. Cornelissen-Steijger et al., ATF3 and Fra1 have opposite functions in JNK- and ERK-dependent DNA damage responses. DNA Repair 7(3), 487\u2013496 (2008)","journal-title":"DNA Repair"},{"issue":"8","key":"907_CR38","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1038\/ni.2065","volume":"12","author":"A Oeckinghaus","year":"2011","unstructured":"A. Oeckinghaus, M.S. Hayden, S. Ghosh, Crosstalk in NF-\u03baB signaling pathways. Nat. Immunol. 12(8), 695\u2013708 (2011)","journal-title":"Nat. Immunol."},{"issue":"16","key":"907_CR39","doi-asserted-by":"publisher","first-page":"2790","DOI":"10.1080\/10408398.2019.1661827","volume":"60","author":"H Khan","year":"2020","unstructured":"H. Khan, H. Ullah, P.C.M.F. Castilho, A.S. Gomila, G. D\u2019Onofrio, R. Filosa et al., Targeting NF-\u03baB signaling pathway in cancer by dietary polyphenols. Crit. Rev. Food Sci. Nutr. 60(16), 2790\u20132800 (2020)","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"907_CR40","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2021.698302","volume":"11","author":"J Ding","year":"2021","unstructured":"J. Ding, H. Li, Y. Liu, Y. Xie, J. Yu, H. Sun et al., OXCT1 enhances gemcitabine resistance through NF-\u03baB pathway in pancreatic ductal adenocarcinoma. Front. Oncol. 11, 698302 (2021)","journal-title":"Front. Oncol."},{"key":"907_CR41","doi-asserted-by":"publisher","first-page":"14470","DOI":"10.1038\/srep14470","volume":"5","author":"JW Kwon","year":"2015","unstructured":"J.W. Kwon, H.K. Kwon, H.J. Shin, Y.M. Choi, M.A. Anwar, S. Choi, Activating transcription factor 3 represses inflammatory responses by binding to the p65 subunit of NF-\u03baB. Sci. Rep. 5, 14470 (2015)","journal-title":"Sci. Rep."},{"issue":"7090","key":"907_CR42","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1038\/nature04768","volume":"441","author":"M Gilchrist","year":"2006","unstructured":"M. Gilchrist, V. Thorsson, B. Li, A.G. Rust, M. Korb, K. Kennedy et al., Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4. Nature 441(7090), 173\u2013178 (2006)","journal-title":"Nature"},{"key":"907_CR43","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1016\/j.toxlet.2018.01.022","volume":"287","author":"F Yan","year":"2018","unstructured":"F. Yan, Y. Wu, H. Liu, Y. Wu, H. Shen, W. Li, ATF3 is positively involved in particulate matter-induced airway inflammation in vitro and in vivo. Toxicol. Lett. 287, 113\u2013121 (2018)","journal-title":"Toxicol. Lett."}],"container-title":["Cellular Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13402-023-00907-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s13402-023-00907-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13402-023-00907-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,2]],"date-time":"2024-07-02T13:04:40Z","timestamp":1719925480000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s13402-023-00907-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,15]]},"references-count":43,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["907"],"URL":"https:\/\/doi.org\/10.1007\/s13402-023-00907-5","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-3172142\/v1","asserted-by":"object"}]},"ISSN":["2211-3428","2211-3436"],"issn-type":[{"value":"2211-3428","type":"print"},{"value":"2211-3436","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,15]]},"assertion":[{"value":"30 November 2023","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 December 2023","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All animal experiments were approved by the Animal Ethics Committee of Shanghai Jiao Tong University (License number: SYXK Shanghai 2018\u20130027).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}