{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T22:27:13Z","timestamp":1793312833269,"version":"4.5.0"},"reference-count":41,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2020,7,14]],"date-time":"2020-07-14T00:00:00Z","timestamp":1594684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},{"start":{"date-parts":[[2020,7,14]],"date-time":"2020-07-14T00:00:00Z","timestamp":1594684800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"funder":[{"name":"Pierre Fabre Dermo-Cosm\u00e9tique"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Dermatol Ther (Heidelb)"],"published-print":{"date-parts":[[2020,10]]},"DOI":"10.1007\/s13555-020-00415-6","type":"journal-article","created":{"date-parts":[[2020,7,14]],"date-time":"2020-07-14T13:29:26Z","timestamp":1594733366000},"page":"1013-1029","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["An Emollient Containing Aquaphilus dolomiae Extract is Effective in the Management of Xerosis and Pruritus: An International, Real-World Study"],"prefix":"10.1007","volume":"10","author":[{"given":"Mette","family":"Deleuran","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor","family":"Georgescu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8185-6198","authenticated-orcid":false,"given":"Catherine","family":"Jean-Decoster","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,7,14]]},"reference":[{"key":"415_CR1","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1046\/j.1529-8019.2003.01635.x","volume":"16","author":"RA Norman","year":"2003","unstructured":"Norman RA. Xerosis and pruritus in the elderly: recognition and management. Dermatol Ther. 2003;16:254\u20139.","journal-title":"Dermatol Ther"},{"key":"415_CR2","doi-asserted-by":"publisher","first-page":"671","DOI":"10.1016\/S0001-7310(08)76171-4","volume":"99","author":"D Barco","year":"2008","unstructured":"Barco D, Gimenez-Arnau A. Xerosis: a dysfunction of the epidermal barrier. Actas Dermosifiliogr. 2008;99:671\u201382.","journal-title":"Actas Dermosifiliogr"},{"key":"415_CR3","first-page":"1135","volume":"68","author":"S Moses","year":"2003","unstructured":"Moses S. Pruritus. Am Fam Phys. 2003;68:1135\u201342.","journal-title":"Am Fam Phys"},{"key":"415_CR4","doi-asserted-by":"publisher","first-page":"803752","DOI":"10.1155\/2015\/803752","volume":"2015","author":"N Tarikci","year":"2015","unstructured":"Tarikci N, Kocaturk E, Gungor S, Topal IO, Can PU, Singer R. Pruritus in systemic diseases: a review of etiological factors and new treatment modalities. Sci World J. 2015;2015:803752.","journal-title":"Sci World J"},{"key":"415_CR5","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1111\/bjd.16117","volume":"178","author":"GWM Millington","year":"2018","unstructured":"Millington GWM, Collins A, Lovell CR, et al. British Association of Dermatologists\u2019 guidelines for the investigation and management of generalized pruritus in adults without an underlying dermatosis, 2018. Br J Dermatol. 2018;178:34\u201360.","journal-title":"Br J Dermatol"},{"key":"415_CR6","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1159\/000334631","volume":"223","author":"C Paul","year":"2011","unstructured":"Paul C, Maumus-Robert S, Mazereeuw-Hautier J, Guyen CN, Saudez X, Schmitt AM. Prevalence and risk factors for xerosis in the elderly: a cross-sectional epidemiological study in primary care. Dermatology. 2011;223:260\u20135.","journal-title":"Dermatology"},{"key":"415_CR7","doi-asserted-by":"publisher","first-page":"1099","DOI":"10.1111\/j.1523-1747.2005.23726.x","volume":"124","author":"AV Rawlings","year":"2005","unstructured":"Rawlings AV, Matts PJ. Stratum corneum moisturization at the molecular level: an update in relation to the dry skin cycle. J Investig Dermatol. 2005;124:1099\u2013110.","journal-title":"J Investig Dermatol"},{"key":"415_CR8","doi-asserted-by":"publisher","first-page":"1153","DOI":"10.1001\/archdermatol.2011.178","volume":"147","author":"SP Kini","year":"2011","unstructured":"Kini SP, DeLong LK, Veledar E, McKenzie-Brown AM, Schaufele M, Chen SC. The impact of pruritus on quality of life: the skin equivalent of pain. Arch Dermatol. 2011;147:1153\u20136.","journal-title":"Arch Dermatol"},{"key":"415_CR9","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1016\/j.sder.2011.04.008","volume":"30","author":"SB Elmariah","year":"2011","unstructured":"Elmariah SB, Lerner EA. Topical therapies for pruritus. Semin Cutan Med Surg. 2011;30:118\u201326.","journal-title":"Semin Cutan Med Surg"},{"key":"415_CR10","first-page":"191","volume":"62","author":"M Bourrain","year":"2012","unstructured":"Bourrain M, Villette C, Nguyen T, Lebaron P. Aquaphilus dolomiae gen. nov., sp. nov., isolated from a deep aquifer. Life Environ. 2012;62:191\u20135.","journal-title":"Life Environ"},{"key":"415_CR11","doi-asserted-by":"publisher","first-page":"421","DOI":"10.2147\/CCID.S113180","volume":"9","author":"MF Aries","year":"2016","unstructured":"Aries MF, Hernandez-Pigeon H, Vaissiere C, et al. Anti-inflammatory and immunomodulatory effects of Aquaphilus dolomiae extract on in vitro models. Clin Cosmet Investig Dermatol. 2016;9:421\u201334.","journal-title":"Clin Cosmet Investig Dermatol"},{"key":"415_CR12","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1111\/jdv.14891","volume":"32","author":"A Wollenberg","year":"2018","unstructured":"Wollenberg A, Barbarot S, Bieber T, et al. Consensus-based European guidelines for treatment of atopic eczema (atopic dermatitis) in adults and children: part I. J Eur Acad Dermatol Venereol. 2018;32:657\u201382.","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"415_CR13","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1111\/pde.12786","volume":"33","author":"P Bianchi","year":"2016","unstructured":"Bianchi P, Theunis J, Casas C, et al. Effects of a new emollient-based treatment on skin microflora balance and barrier function in children with mild atopic dermatitis. Pediatr Dermatol. 2016;33:165\u201371.","journal-title":"Pediatr Dermatol"},{"key":"415_CR14","doi-asserted-by":"publisher","first-page":"497","DOI":"10.2340\/00015555-1265","volume":"92","author":"A Reich","year":"2012","unstructured":"Reich A, Heisig M, Phan NQ, et al. Visual analogue scale: evaluation of the instrument for the assessment of pruritus. Acta Derm Venereol. 2012;92:497\u2013501.","journal-title":"Acta Derm Venereol"},{"key":"415_CR15","doi-asserted-by":"crossref","unstructured":"European Task Force on Atopic Dermatitis. Severity scoring of atopic dermatitis: the SCORAD index. Consensus Report of the European Task Force on Atopic Dermatitis. Dermatology. 1993;186:23\u201331.","DOI":"10.1159\/000247298"},{"key":"415_CR16","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1046\/j.1365-2133.2003.05157.x","volume":"148","author":"SA Holme","year":"2003","unstructured":"Holme SA, Man I, Sharpe JL, Dykes PJ, Lewis-Jones MS, Finlay AY. The Children\u2019s Dermatology Life Quality Index: validation of the cartoon version. Br J Dermatol. 2003;148:285\u201390.","journal-title":"Br J Dermatol"},{"key":"415_CR17","doi-asserted-by":"publisher","first-page":"942","DOI":"10.1111\/j.1365-2133.1995.tb16953.x","volume":"132","author":"MS Lewis-Jones","year":"1995","unstructured":"Lewis-Jones MS, Finlay AY. The Children\u2019s Dermatology Life Quality Index (CDLQI): initial validation and practical use. Br J Dermatol. 1995;132:942\u20139.","journal-title":"Br J Dermatol"},{"key":"415_CR18","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1111\/j.1365-2230.1994.tb01167.x","volume":"19","author":"AY Finlay","year":"1994","unstructured":"Finlay AY, Khan GK. Dermatology Life Quality Index (DLQI)\u2014a simple practical measure for routine clinical use. Clin Exp Dermatol. 1994;19:210\u20136.","journal-title":"Clin Exp Dermatol"},{"key":"415_CR19","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1111\/j.0022-202X.2005.23621.x","volume":"125","author":"Y Hongbo","year":"2005","unstructured":"Hongbo Y, Thomas CL, Harrison MA, Salek MS, Finlay AY. Translating the science of quality of life into practice: what do dermatology life quality index scores mean? J Investig Dermatol. 2005;125:659\u201364.","journal-title":"J Investig Dermatol"},{"key":"415_CR20","doi-asserted-by":"crossref","unstructured":"Song J, Xian D, Yang L, Xiong X, Lai R, Zhong J. Pruritus: progress toward pathogenesis and treatment. Biomed Res Int.\n2018;2018:9625936.","DOI":"10.1155\/2018\/9625936"},{"key":"415_CR21","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1684\/ejd.2017.2994","volume":"27","author":"AC Fostini","year":"2017","unstructured":"Fostini AC, Georgescu V, Decoster CJ, Girolomoni G. A cream based on Aquaphilus dolomiae extracts alleviates non-histaminergic pruritus in humans. Eur J Dermatol. 2017;27:317\u20138.","journal-title":"Eur J Dermatol"},{"key":"415_CR22","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1016\/j.jaad.2014.03.023","volume":"71","author":"LF Eichenfield","year":"2014","unstructured":"Eichenfield LF, Tom WL, Berger TG, et al. Guidelines of care for the management of atopic dermatitis: section\u00a02. Management and treatment of atopic dermatitis with topical therapies. J Am Acad Dermatol. 2014;71:116\u201332.","journal-title":"J Am Acad Dermatol"},{"key":"415_CR23","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1159\/000096915","volume":"214","author":"R Grimalt","year":"2007","unstructured":"Grimalt R, Mengeaud V, Cambazard F, Study Investigators\u2019 Group. The steroid-sparing effect of an emollient therapy in infants with atopic dermatitis: a randomized controlled study. Dermatology. 2007;214:61\u20137.","journal-title":"Dermatology"},{"key":"415_CR24","doi-asserted-by":"publisher","first-page":"212530","DOI":"10.7573\/dic.212530","volume":"7","author":"KL Hon","year":"2018","unstructured":"Hon KL, Kung JSC, Ng WGG, Leung TF. Emollient treatment of atopic dermatitis: latest evidence and clinical considerations. Drugs Context. 2018;7:212530.","journal-title":"Drugs Context"},{"key":"415_CR25","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1111\/pde.13113","volume":"34","author":"GS Tiplica","year":"2017","unstructured":"Tiplica GS, Kaszuba A, Malinauskiene L, et al. Prevention of flares in children with atopic dermatitis with regular use of an emollient containing glycerol and paraffin: a randomized controlled study. Pediatr Dermatol. 2017;34:282\u20139.","journal-title":"Pediatr Dermatol"},{"key":"415_CR26","doi-asserted-by":"publisher","first-page":"948","DOI":"10.2340\/00015555-2395","volume":"96","author":"SA Koppes","year":"2016","unstructured":"Koppes SA, Charles F, Lammers LA, Frings-Dresen M, Kezic S, Ruste-Meyer T. Efficacy of a cream containing ceramides and magnesium in the treatment of mild to moderate atopic dermatitis: a randomized, double-blind, emollient-and hydrocortisone-controlled trial. Acta Derm Venereol. 2016;96:948\u201353.","journal-title":"Acta Derm Venereol"},{"issue":"Suppl 1","key":"415_CR27","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1111\/jdv.14077","volume":"31","author":"J Theunis","year":"2017","unstructured":"Theunis J, Chaussade H, Bourgeois O, Mengeaud V. Efficacy of a Rhealba(\u00ae) Oat Extract-based emollient on chronic pruritus in elderly French outpatients. J Eur Acad Dermatol Venereol. 2017;31(Suppl 1):1\u20137.","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"415_CR28","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1177\/0394632017736674","volume":"30","author":"E Del Duca","year":"2017","unstructured":"Del Duca E, Farnetani F, De Carvalho N, Bottoni U, Pellacani G, Nistico SP. Superiority of a vitamin B12-containing emollient compared to a standard emollient in the maintenance treatment of mild-to-moderate plaque psoriasis. Int J Immunopathol Pharmacol. 2017;30:439\u201344.","journal-title":"Int J Immunopathol Pharmacol"},{"key":"415_CR29","doi-asserted-by":"publisher","first-page":"458","DOI":"10.7547\/16-119","volume":"108","author":"JC Parker","year":"2018","unstructured":"Parker JC, Scharfbillig RW, Jones S. Effectiveness of two moisturizers in the treatment of foot xerosis a randomized clinical trial. J Am Podiatr Med Assoc. 2018;108:458\u201365.","journal-title":"J Am Podiatr Med Assoc"},{"key":"415_CR30","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1111\/ijd.13454","volume":"56","author":"F Boralevi","year":"2017","unstructured":"Boralevi F, Meledie N\u2019Djong AP, Yao Yoboue P, et al. Regression of cutaneous xerosis with emollient treatment in sub-Saharan African patients. Int J Dermatol. 2017;56:467\u201373.","journal-title":"Int J Dermatol"},{"key":"415_CR31","doi-asserted-by":"publisher","first-page":"960","DOI":"10.1016\/S1473-3099(15)00132-2","volume":"15","author":"L Romani","year":"2015","unstructured":"Romani L, Steer AC, Whitfeld MJ, Kaldor JM. Prevalence of scabies and impetigo worldwide: a systematic review. Lancet Infect Dis. 2015;15:960\u20137.","journal-title":"Lancet Infect Dis"},{"key":"415_CR32","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1111\/ddg.13706","volume":"17","author":"C Sunderkotter","year":"2019","unstructured":"Sunderkotter C, Aebischer A, Neufeld M, et al. Increase of scabies in Germany and development of resistant mites? Evidence and consequences. J Dtsch Dermatol Ges. 2019;17:15\u201323.","journal-title":"J Dtsch Dermatol Ges"},{"key":"415_CR33","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1016\/j.tmaid.2019.02.002","volume":"29","author":"L Lugovic-Mihic","year":"2019","unstructured":"Lugovic-Mihic L. The increase in Croatia\u2019s scabies incidence: how did refugees and traveling contribute? Travel Med Infect Dis. 2019;29:74.","journal-title":"Travel Med Infect Dis"},{"key":"415_CR34","first-page":"24","volume":"2019","author":"E Amato","year":"2019","unstructured":"Amato E, Dansie LS, Groneng GM, et al. Increase of scabies infestations, Norway, 2006 to 2018. Euro Surveill. 2019;2019:24.","journal-title":"Euro Surveill"},{"key":"415_CR35","doi-asserted-by":"publisher","first-page":"1248","DOI":"10.1111\/jdv.14351","volume":"31","author":"CM Salavastru","year":"2017","unstructured":"Salavastru CM, Chosidow O, Boffa MJ, Janier M, Tiplica GS. European guideline for the management of scabies. J Eur Acad Dermatol Venereol. 2017;31:1248\u201353.","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"415_CR36","doi-asserted-by":"publisher","first-page":"163","DOI":"10.2147\/CCID.S188070","volume":"12","author":"EH Kowalski","year":"2019","unstructured":"Kowalski EH, Kneiber D, Valdebran M, Patel U, Amber KT. Treatment-resistant prurigo nodularis: challenges and solutions. Clin Cosmet Investig Dermatol. 2019;12:163\u201372.","journal-title":"Clin Cosmet Investig Dermatol"},{"key":"415_CR37","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1007\/s13555-017-0192-3","volume":"7","author":"C Jeon","year":"2017","unstructured":"Jeon C, Yan D, Nakamura M, et al. Frequency and management of sleep disturbance in adults with atopic dermatitis: a systematic review. Dermatol Ther (Heidelb). 2017;7:349\u201364.","journal-title":"Dermatol Ther (Heidelb)"},{"key":"415_CR38","doi-asserted-by":"publisher","first-page":"745","DOI":"10.1001\/archpedi.159.8.745","volume":"159","author":"SL Chamlin","year":"2005","unstructured":"Chamlin SL, Mattson CL, Frieden IJ, et al. The price of pruritus: sleep disturbance and cosleeping in atopic dermatitis. Arch Pediatr Adolesc Med. 2005;159:745\u201350.","journal-title":"Arch Pediatr Adolesc Med"},{"key":"415_CR39","doi-asserted-by":"publisher","first-page":"110","DOI":"10.2174\/1573396313666171117114005","volume":"14","author":"KL Hon","year":"2018","unstructured":"Hon KL, Kung JSC, Tsang KYC, Yu JWS, Lee VW, Leung TF. Testing the actions of a multi-action emollient: patient\u2019s acceptability determines product efficacy. Curr Pediatr Rev. 2018;14:110\u20136.","journal-title":"Curr Pediatr Rev"},{"key":"415_CR40","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1007\/s40257-015-0146-4","volume":"16","author":"JD Lindh","year":"2015","unstructured":"Lindh JD, Bradley M. Clinical effectiveness of moisturizers in atopic dermatitis and related disorders: a systematic review. Am J Clin Dermatol. 2015;16:341\u201359.","journal-title":"Am J Clin Dermatol"},{"key":"415_CR41","doi-asserted-by":"publisher","first-page":"1180","DOI":"10.1111\/jdv.14849","volume":"32","author":"GS Tiplica","year":"2018","unstructured":"Tiplica GS, Boralevi F, Konno P, et al. The regular use of an emollient improves symptoms of atopic dermatitis in children: a randomized controlled study. J Eur Acad Dermatol Venereol. 2018;32:1180\u20137.","journal-title":"J Eur Acad Dermatol Venereol"}],"container-title":["Dermatology and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13555-020-00415-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s13555-020-00415-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13555-020-00415-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,15]],"date-time":"2024-03-15T13:15:35Z","timestamp":1710508535000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s13555-020-00415-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,14]]},"references-count":41,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,10]]}},"alternative-id":["415"],"URL":"https:\/\/doi.org\/10.1007\/s13555-020-00415-6","relation":{},"ISSN":["2193-8210","2190-9172"],"issn-type":[{"value":"2193-8210","type":"print"},{"value":"2190-9172","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7,14]]},"assertion":[{"value":"29 April 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 July 2020","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}