{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T03:02:27Z","timestamp":1793847747053,"version":"4.6.1"},"reference-count":12,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},{"start":{"date-parts":[[2024,3,5]],"date-time":"2024-03-05T00:00:00Z","timestamp":1709596800000},"content-version":"vor","delay-in-days":4,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Dermatol Ther (Heidelb)"],"published-print":{"date-parts":[[2024,3]]},"DOI":"10.1007\/s13555-024-01117-z","type":"journal-article","created":{"date-parts":[[2024,3,5]],"date-time":"2024-03-05T04:29:21Z","timestamp":1709612961000},"page":"813-817","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Successful Treatment of Disseminated Granuloma Annulare with Upadacitinib"],"prefix":"10.1007","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0713-8283","authenticated-orcid":false,"given":"Axel","family":"De Greef","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ghita","family":"Benjelloun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9936-9868","authenticated-orcid":false,"given":"Evelyne","family":"Harkemanne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0499-7939","authenticated-orcid":false,"given":"Marie","family":"Baeck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,3,5]]},"reference":[{"issue":"4","key":"1117_CR1","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1007\/s40257-013-0029-5","volume":"14","author":"LA Thornsberry","year":"2013","unstructured":"Thornsberry LA, English JC 3rd. Etiology, diagnosis, and therapeutic management of granuloma annulare: an update. Am J Clin Dermatol. 2013;14(4):279\u201390. https:\/\/doi.org\/10.1007\/s40257-013-0029-5.","journal-title":"Am J Clin Dermatol"},{"issue":"4","key":"1117_CR2","doi-asserted-by":"publisher","DOI":"10.5826\/dpc.1204a173","volume":"12","author":"R Fornons-Servent","year":"2022","unstructured":"Fornons-Servent R, Bauer-Alonso A, Llobera-Ris C, Pen\u00edn RM, Marcoval J. Granuloma annulare: a case\u2013control study of possible associated diseases. Dermatol Pract Concept. 2022;12(4): e2022173. https:\/\/doi.org\/10.5826\/dpc.1204a173.","journal-title":"Dermatol Pract Concept"},{"key":"1117_CR3","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1016\/j.jdcr.2021.09.023","volume":"17","author":"BD Rankin","year":"2021","unstructured":"Rankin BD, Haber RM. Familial granuloma annulare: first report of occurrence in a father and daughter and updated review of the literature. JAAD Case Rep. 2021;17:61\u20134. https:\/\/doi.org\/10.1016\/j.jdcr.2021.09.023.","journal-title":"JAAD Case Rep"},{"issue":"8","key":"1117_CR4","doi-asserted-by":"publisher","first-page":"1467","DOI":"10.1111\/jdv.12976","volume":"29","author":"J Luk\u00e1cs","year":"2015","unstructured":"Luk\u00e1cs J, Schliemann S, Elsner P. Treatment of generalized granuloma annulare\u2014a systematic review. J Eur Acad Dermatol Venereol. 2015;29(8):1467\u201380. https:\/\/doi.org\/10.1111\/jdv.12976.","journal-title":"J Eur Acad Dermatol Venereol"},{"issue":"1","key":"1117_CR5","doi-asserted-by":"publisher","DOI":"10.1111\/dth.15188","volume":"35","author":"K Dopytalska","year":"2022","unstructured":"Dopytalska K, Gabzdyl N, Szczerba M, Szyma\u0144ska E, Walecka I. Is biologic therapy the future of granuloma annulare treatment? Dermatol Ther. 2022;35(1):e15188. https:\/\/doi.org\/10.1111\/dth.15188.","journal-title":"Dermatol Ther"},{"issue":"1","key":"1117_CR6","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1016\/j.jaad.2019.12.028","volume":"83","author":"MS Min","year":"2020","unstructured":"Min MS, Wu J, He H, et al. Granuloma annulare skin profile shows activation of T-helper cell type\u00a01, T-helper cell type\u00a02, and Janus kinase pathways. J Am Acad Dermatol. 2020;83(1):63\u201370. https:\/\/doi.org\/10.1016\/j.jaad.2019.12.028.","journal-title":"J Am Acad Dermatol"},{"issue":"3","key":"1117_CR7","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1016\/j.cytogfr.2012.04.003","volume":"23","author":"S O'Reilly","year":"2012","unstructured":"O\u2019Reilly S, Ciechomska M, Cant R, H\u00fcgle T, van Laar JM. Interleukin-6, its role in fibrosing conditions. Cytokine Growth Factor Rev. 2012;23(3):99\u2013107. https:\/\/doi.org\/10.1016\/j.cytogfr.2012.04.003.","journal-title":"Cytokine Growth Factor Rev"},{"issue":"3","key":"1117_CR8","doi-asserted-by":"publisher","first-page":"400","DOI":"10.1111\/ajd.13875","volume":"63","author":"X Bosch-Amate","year":"2022","unstructured":"Bosch-Amate X, Serra-Garc\u00eda L, Alamon-Reig F, et al. Treatment of granuloma annulare with tofacitinib. Austral J Dermatol. 2022;63(3):400\u20133. https:\/\/doi.org\/10.1111\/ajd.13875.","journal-title":"Austral J Dermatol"},{"issue":"4","key":"1117_CR9","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1093\/ced\/llac110","volume":"48","author":"D Kim","year":"2023","unstructured":"Kim D, Kang HY. Rapid improvement of refractory generalized granuloma annulare with the Janus kinase inhibitor baricitinib in two patients. Clin Exp Dermatol. 2023;48(4):375\u20136. https:\/\/doi.org\/10.1093\/ced\/llac110.","journal-title":"Clin Exp Dermatol"},{"issue":"8","key":"1117_CR10","doi-asserted-by":"publisher","DOI":"10.1111\/dth.15641","volume":"35","author":"A Ballov\u00e1","year":"2022","unstructured":"Ballov\u00e1 A, Kme\u010dov\u00e1 Z, P\u00e9\u010d J, Vor\u010d\u00e1kov\u00e1 K. Recalcitrant granuloma annulare induced by two different biologic agents resolved after Janus kinase inhibitor treatment. Dermatol Ther. 2022;35(8):e15641. https:\/\/doi.org\/10.1111\/dth.15641.","journal-title":"Dermatol Ther"},{"key":"1117_CR11","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1016\/j.jdcr.2023.01.027","volume":"34","author":"KN Slater","year":"2023","unstructured":"Slater KN, Valk B, Kartono F. A case of generalized granuloma annulare treated with upadacitinib. JAAD Case Rep. 2023;34:12\u20134. https:\/\/doi.org\/10.1016\/j.jdcr.2023.01.027.","journal-title":"JAAD Case Rep"},{"issue":"1","key":"1117_CR12","doi-asserted-by":"publisher","DOI":"10.1111\/dth.15211","volume":"35","author":"W Sondermann","year":"2022","unstructured":"Sondermann W, Hadaschik E, Specker C. Successful therapy of disseminated patch-type granuloma annulare with upadacitinib in a patient with rheumatoid arthritis. Dermatol Ther. 2022;35(1):e15211. https:\/\/doi.org\/10.1111\/dth.15211.","journal-title":"Dermatol Ther"}],"container-title":["Dermatology and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13555-024-01117-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s13555-024-01117-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13555-024-01117-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,27]],"date-time":"2024-03-27T06:06:27Z","timestamp":1711519587000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s13555-024-01117-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3]]},"references-count":12,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,3]]}},"alternative-id":["1117"],"URL":"https:\/\/doi.org\/10.1007\/s13555-024-01117-z","relation":{},"ISSN":["2193-8210","2190-9172"],"issn-type":[{"value":"2193-8210","type":"print"},{"value":"2190-9172","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3]]},"assertion":[{"value":"17 January 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 February 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 March 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Marie Baeck discloses her past participation on the upadacitinib advisory boards organized by AbbVie. Axel De Greef and Marie Baeck have previously participated as speakers in events sponsored by AbbVie. Ghita Benjelloun and Evelyne Harkemanne disclose no conflict of interest. All the authors declare that the current study was conducted in an independent manner.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"This case report and data collection were conducted with the approval of the hospital and faculty institutional review board (Commission d\u2019Ethique Biom\u00e9dicale Hospitalo-Facultaire) of Universit\u00e9 catholique de Louvain (UCLouvain), Belgium. All procedures in this study were in accordance with the 1964 Helsinki declaration (and its amendments). The patient in this manuscript has given written informed consent to participate and for publication of her case details.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval"}}]}}