{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T12:37:09Z","timestamp":1764333429798,"version":"3.37.3"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},{"start":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T00:00:00Z","timestamp":1713225600000},"content-version":"vor","delay-in-days":15,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"funder":[{"DOI":"10.13039\/100004319","name":"Pfizer","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004319","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Dermatol Ther (Heidelb)"],"published-print":{"date-parts":[[2024,4]]},"DOI":"10.1007\/s13555-024-01145-9","type":"journal-article","created":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T08:02:01Z","timestamp":1713254521000},"page":"993-1006","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The Epidemiology of Hospital-Treated Alopecia Areata in Denmark, 1995\u20132016"],"prefix":"10.1007","volume":"14","author":[{"given":"Sissel Brandt Toft","family":"S\u00f8rensen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prethibha","family":"George","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oladayo","family":"Jagun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Wolk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lynne","family":"Napatalung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel H.","family":"Zwillich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lars","family":"Iversen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vera","family":"Ehrenstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,4,16]]},"reference":[{"issue":"1","key":"1145_CR1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jaad.2017.04.1141","volume":"78","author":"LC Strazzulla","year":"2018","unstructured":"Strazzulla LC, Wang EHC, Avila L, et al. Alopecia areata: disease characteristics, clinical evaluation, and new perspectives on pathogenesis. J Am Acad Dermatol. 2018;78(1):1\u201312.","journal-title":"J Am Acad Dermatol"},{"issue":"1","key":"1145_CR2","doi-asserted-by":"publisher","first-page":"S13","DOI":"10.1038\/jidsymp.2013.4","volume":"16","author":"MK Hordinsky","year":"2013","unstructured":"Hordinsky MK. Overview of alopecia areata. J Investig Dermatol Symp Proc. 2013;16(1):S13-15.","journal-title":"J Investig Dermatol Symp Proc"},{"issue":"1764","key":"1145_CR3","first-page":"29","volume":"257","author":"KJ MacLean","year":"2013","unstructured":"MacLean KJ, Tidman MJ. Alopecia areata: more than skin deep. Practitioner. 2013;257(1764):29\u201332, 3.","journal-title":"Practitioner"},{"unstructured":"National Alopecia Areata Foundation. 2022. https:\/\/www.naaf.org\/faqs. Accessed 2022-05-07.","key":"1145_CR4"},{"key":"1145_CR5","first-page":"397","volume":"8","author":"AC Villasante Fricke","year":"2015","unstructured":"Villasante Fricke AC, Miteva M. Epidemiology and burden of alopecia areata: a systematic review. Clin Cosmet Investig Dermatol. 2015;8:397\u2013403.","journal-title":"Clin Cosmet Investig Dermatol"},{"issue":"4","key":"1145_CR6","doi-asserted-by":"publisher","first-page":"1141","DOI":"10.1038\/jid.2013.464","volume":"134","author":"SA Mirzoyev","year":"2014","unstructured":"Mirzoyev SA, Schrum AG, Davis MDP, Torgerson RR. Lifetime incidence risk of alopecia areata estimated at 2.1% by Rochester Epidemiology Project, 1990\u20132009. J Investig Dermatol. 2014;134(4):1141\u20132.","journal-title":"J Investig Dermatol"},{"issue":"8","key":"1145_CR7","doi-asserted-by":"publisher","first-page":"1490","DOI":"10.1111\/jdv.18926","volume":"37","author":"A Muntyanu","year":"2023","unstructured":"Muntyanu A, Gabrielli S, Donovan J, et al. The burden of alopecia areata: a scoping review focusing on quality of life, mental health and work productivity. J Eur Acad Dermatol Venereol. 2023;37(8):1490\u2013520.","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"1145_CR8","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.c3671","volume":"341","author":"MJ Harries","year":"2010","unstructured":"Harries MJ, Sun J, Paus R, King LE Jr. Management of alopecia areata. BMJ. 2010;341:c3671.","journal-title":"BMJ"},{"issue":"2","key":"1145_CR9","doi-asserted-by":"publisher","first-page":"51","DOI":"10.4103\/ijt.ijt_99_17","volume":"10","author":"E Darwin","year":"2018","unstructured":"Darwin E, Hirt PA, Fertig R, Doliner B, Delcanto G, Jimenez JJ. Alopecia areata: review of epidemiology, clinical features, pathogenesis, and new treatment options. Int J Trichol. 2018;10(2):51\u201360.","journal-title":"Int J Trichol"},{"issue":"5","key":"1145_CR10","doi-asserted-by":"publisher","first-page":"1092","DOI":"10.1111\/bjd.18145","volume":"181","author":"JH Lee","year":"2019","unstructured":"Lee JH, Kim HJ, Han KD, et al. Incidence and prevalence of alopecia areata according to subtype: a nationwide, population-based study in South Korea (2006\u20132015). Br J Dermatol. 2019;181(5):1092\u20133.","journal-title":"Br J Dermatol"},{"issue":"2","key":"1145_CR11","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1111\/bjd.20628","volume":"186","author":"M Harries","year":"2022","unstructured":"Harries M, Macbeth AE, Holmes S, et al. The epidemiology of alopecia areata: a population-based cohort study in UK primary care. Br J Dermatol. 2022;186(2):257\u201365.","journal-title":"Br J Dermatol"},{"key":"1145_CR12","doi-asserted-by":"publisher","first-page":"259","DOI":"10.2147\/CCID.S245649","volume":"13","author":"M Benigno","year":"2020","unstructured":"Benigno M, Anastassopoulos KP, Mostaghimi A, et al. A large cross-sectional survey study of the prevalence of alopecia areata in the United States. Clin Cosmet Investig Dermatol. 2020;13:259\u201366.","journal-title":"Clin Cosmet Investig Dermatol"},{"key":"1145_CR13","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1001\/jamadermatol.2023.0002","volume":"159","author":"A Mostaghimi","year":"2023","unstructured":"Mostaghimi A, Gao W, Ray M, et al. Trends in prevalence and incidence of alopecia areata, alopecia totalis, and alopecia universalis among adults and children in a US employer-sponsored insured population. JAMA Dermatol. 2023;159:411\u20138.","journal-title":"JAMA Dermatol"},{"issue":"1","key":"1145_CR14","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jaut.2007.05.002","volume":"29","author":"WW Eaton","year":"2007","unstructured":"Eaton WW, Rose NR, Kalaydjian A, Pedersen MG, Mortensen PB. Epidemiology of autoimmune diseases in Denmark. J Autoimmun. 2007;29(1):1\u20139.","journal-title":"J Autoimmun"},{"issue":"1\u20133","key":"1145_CR15","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1007\/s12026-009-8153-2","volume":"47","author":"WW Eaton","year":"2010","unstructured":"Eaton WW, Pedersen MG, Atladottir HO, Gregory PE, Rose NR, Mortensen PB. The prevalence of 30 ICD-10 autoimmune diseases in Denmark. Immunol Res. 2010;47(1\u20133):228\u201331.","journal-title":"Immunol Res"},{"key":"1145_CR16","doi-asserted-by":"publisher","first-page":"533","DOI":"10.2147\/CLEP.S314959","volume":"13","author":"K Laugesen","year":"2021","unstructured":"Laugesen K, Ludvigsson JF, Schmidt M, et al. Nordic health registry-based research: a review of health care systems and key registries. Clin Epidemiol. 2021;13:533\u201354.","journal-title":"Clin Epidemiol"},{"issue":"8","key":"1145_CR17","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1007\/s10654-014-9930-3","volume":"29","author":"M Schmidt","year":"2014","unstructured":"Schmidt M, Pedersen L, S\u00f8rensen HT. The Danish Civil Registration System as a tool in epidemiology. Eur J Epidemiol. 2014;29(8):541\u20139.","journal-title":"Eur J Epidemiol"},{"key":"1145_CR18","doi-asserted-by":"publisher","first-page":"449","DOI":"10.2147\/CLEP.S91125","volume":"7","author":"M Schmidt","year":"2015","unstructured":"Schmidt M, Schmidt SA, Sandegaard JL, Ehrenstein V, Pedersen L, Sorensen HT. The Danish National Patient Registry: a review of content, data quality, and research potential. Clin Epidemiol. 2015;7:449\u201390.","journal-title":"Clin Epidemiol"},{"issue":"7 Suppl","key":"1145_CR19","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1177\/1403494810393562","volume":"39","author":"ML Gjerstorff","year":"2011","unstructured":"Gjerstorff ML. The Danish Cancer Registry. Scand J Public Health. 2011;39(7 Suppl):42\u20135.","journal-title":"Scand J Public Health"},{"issue":"7 Suppl","key":"1145_CR20","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1177\/1403494811399958","volume":"39","author":"K Helweg-Larsen","year":"2011","unstructured":"Helweg-Larsen K. The Danish register of causes of death. Scand J Public Health. 2011;39(7 Suppl):26\u20139.","journal-title":"Scand J Public Health"},{"key":"1145_CR21","doi-asserted-by":"publisher","first-page":"303","DOI":"10.2147\/CLEP.S37587","volume":"4","author":"SA Johannesdottir","year":"2012","unstructured":"Johannesdottir SA, Horvath-Puho E, Ehrenstein V, Schmidt M, Pedersen L, Sorensen HT. Existing data sources for clinical epidemiology: the Danish National Database of Reimbursed Prescriptions. Clin Epidemiol. 2012;4:303\u201313.","journal-title":"Clin Epidemiol"},{"key":"1145_CR22","doi-asserted-by":"publisher","first-page":"1003","DOI":"10.1111\/pde.15378","volume":"40","author":"M Hordinsky","year":"2023","unstructured":"Hordinsky M, Hebert AA, Gooderham M, et al. Efficacy and safety of ritlecitinib in adolescents with alopecia areata: results from the ALLEGRO phase\u00a02b\/3 randomized, double-blind, placebo-controlled trial. Pediatr Dermatol. 2023;40:1003\u20139.","journal-title":"Pediatr Dermatol"},{"issue":"10387","key":"1145_CR23","doi-asserted-by":"publisher","first-page":"1518","DOI":"10.1016\/S0140-6736(23)00222-2","volume":"401","author":"B King","year":"2023","unstructured":"King B, Zhang X, Harcha WG, et al. Efficacy and safety of ritlecitinib in adults and adolescents with alopecia areata: a randomised, double-blind, multicentre, phase\u00a02b\u20133 trial. Lancet. 2023;401(10387):1518\u201329.","journal-title":"Lancet"},{"issue":"2","key":"1145_CR24","doi-asserted-by":"publisher","first-page":"566","DOI":"10.1016\/j.jaad.2018.08.040","volume":"80","author":"LY Liu","year":"2019","unstructured":"Liu LY, King BA. Ruxolitinib for the treatment of severe alopecia areata. J Am Acad Dermatol. 2019;80(2):566\u20138.","journal-title":"J Am Acad Dermatol"},{"unstructured":"Danmarks Statistik. https:\/\/www.statistikbanken.dk\/statbank5a\/default.asp?w=1920. Accessed 8 Apr 2024.","key":"1145_CR25"},{"issue":"4","key":"1145_CR26","doi-asserted-by":"publisher","first-page":"651","DOI":"10.1111\/ced.14507","volume":"46","author":"A Egeberg","year":"2021","unstructured":"Egeberg A, Anderson S, Edson-Heredia E, Burge R. Comorbidities of alopecia areata: a population-based cohort study. Clin Exp Dermatol. 2021;46(4):651\u20136.","journal-title":"Clin Exp Dermatol"},{"issue":"9","key":"1145_CR27","doi-asserted-by":"publisher","first-page":"1121","DOI":"10.1111\/1346-8138.16839","volume":"50","author":"P George","year":"2023","unstructured":"George P, Jagun O, Liu Q, et al. Prevalence of autoimmune and inflammatory diseases and mental health conditions among an alopecia areata cohort from a US administrative claims database. J Dermatol. 2023;50(9):1121\u20138.","journal-title":"J Dermatol"},{"issue":"4","key":"1145_CR28","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1159\/000530784","volume":"239","author":"KH Lien","year":"2023","unstructured":"Lien KH, Ger TY, Chi CC. Association of alopecia areata with sensorineural hearing loss: a systematic review and meta-analysis. Dermatology. 2023;239(4):523\u201332.","journal-title":"Dermatology"},{"issue":"3","key":"1145_CR29","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1016\/j.yfrne.2014.04.004","volume":"35","author":"ST Ngo","year":"2014","unstructured":"Ngo ST, Steyn FJ, McCombe PA. Gender differences in autoimmune disease. Front Neuroendocrinol. 2014;35(3):347\u201369.","journal-title":"Front Neuroendocrinol"},{"issue":"2","key":"1145_CR30","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1007\/s40257-018-0405-2","volume":"20","author":"DH Marks","year":"2019","unstructured":"Marks DH, Penzi LR, Ibler E, et al. The medical and psychosocial associations of alopecia: recognizing hair loss as more than a cosmetic concern. Am J Clin Dermatol. 2019;20(2):195\u2013200.","journal-title":"Am J Clin Dermatol"},{"issue":"4","key":"1145_CR31","first-page":"409","volume":"13","author":"M Lundin","year":"2014","unstructured":"Lundin M, Chawa S, Sachdev A, Bhanusali D, Seiffert-Sinha K, Sinha AA. Gender differences in alopecia areata. J Drugs Dermatol. 2014;13(4):409\u201313.","journal-title":"J Drugs Dermatol"},{"issue":"2","key":"1145_CR32","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2021-053137","volume":"12","author":"YMF Andersen","year":"2022","unstructured":"Andersen YMF, Nymand L, DeLozier AM, Burge R, Edson-Heredia E, Egeberg A. Patient characteristics and disease burden of alopecia areata in the Danish Skin Cohort. BMJ Open. 2022;12(2):e053137.","journal-title":"BMJ Open"},{"issue":"1","key":"1145_CR33","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1159\/000510880","volume":"7","author":"TK Uzuncakmak","year":"2021","unstructured":"Uzuncakmak TK, Engin B, Serdaroglu S, Tuzun Y. Demographic and clinical features of 1,641 patients with alopecia areata, alopecia totalis, and alopecia universalis: a single-center retrospective study. Skin Appendage Disord. 2021;7(1):8\u201312.","journal-title":"Skin Appendage Disord"},{"issue":"9","key":"1145_CR34","doi-asserted-by":"publisher","first-page":"e331","DOI":"10.1111\/1346-8138.14863","volume":"46","author":"BW Soh","year":"2019","unstructured":"Soh BW, Kim SM, Kim YC, Choi GS, Choi JW. Increasing prevalence of alopecia areata in South Korea. J Dermatol. 2019;46(9):e331\u20132.","journal-title":"J Dermatol"},{"issue":"1","key":"1145_CR35","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1097\/EDE.0000000000001542","volume":"34","author":"J Chubak","year":"2023","unstructured":"Chubak J, Dalmat RR, Weiss NS, Doria-Rose VP, Corley DA, Kamineni A. Informative presence in electronic health record data: a challenge in implementing study exclusion criteria. Epidemiology. 2023;34(1):29\u201332.","journal-title":"Epidemiology"},{"issue":"4","key":"1145_CR36","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1016\/j.jaad.2009.04.031","volume":"61","author":"N Barahmani","year":"2009","unstructured":"Barahmani N, Schabath MB, Duvic M. History of atopy or autoimmunity increases risk of alopecia areata. J Am Acad Dermatol. 2009;61(4):581\u201391.","journal-title":"J Am Acad Dermatol"},{"key":"1145_CR37","doi-asserted-by":"publisher","first-page":"151","DOI":"10.12691\/ijcd-3-4-8","volume":"3","author":"A Lerner","year":"2015","unstructured":"Lerner A, Patricia W, Matthias T. The world incidence and prevalence of autoimmune diseases is increasing. Int J Celiac Dis. 2015;3:151\u20135.","journal-title":"Int J Celiac Dis"},{"key":"1145_CR38","doi-asserted-by":"publisher","DOI":"10.3402\/ecrj.v2.24642","author":"SF Thomsen","year":"2015","unstructured":"Thomsen SF. Epidemiology and natural history of atopic diseases. Eur Clin Respir J. 2015. https:\/\/doi.org\/10.3402\/ecrj.v2.24642.","journal-title":"Eur Clin Respir J"}],"container-title":["Dermatology and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13555-024-01145-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s13555-024-01145-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13555-024-01145-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,27]],"date-time":"2024-04-27T02:33:43Z","timestamp":1714185223000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s13555-024-01145-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4]]},"references-count":38,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,4]]}},"alternative-id":["1145"],"URL":"https:\/\/doi.org\/10.1007\/s13555-024-01145-9","relation":{},"ISSN":["2193-8210","2190-9172"],"issn-type":[{"type":"print","value":"2193-8210"},{"type":"electronic","value":"2190-9172"}],"subject":[],"published":{"date-parts":[[2024,4]]},"assertion":[{"value":"20 December 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 March 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 April 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"At the time of study completion, Prethibha George and Oladayo Jagun were employees of Pfizer Inc and may hold stock or stock options in Pfizer Inc; Prethibha George has no current affiliation. Robert Wolk, Lynne Napatalung, and Samuel H. Zwilich are employees of and may hold stock or stock options in Pfizer Inc. All other authors are employees of their respective institutions.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"According to Danish law, studies based exclusively on routinely collected registry data are exempt from ethical approval or informed consent. This study was reported to the Danish Data Protection Agency, via registration with Aarhus University, record number 2016-051-000001\/serial number 605.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}}]}}