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Stephan Grabbe: Grants or contracts from any entity: Novartis, Pierre Fabre | Consulting fees: AbbVie, BMS, MSD, Genzyme, Klinge Pharma, Sun Pharma, Kyowa-Kirin, Novartis, Pierre Fabre | Participation on a Data Safety Monitoring Board or Advisory Board: Alcedis | Leadership or fiduciary role in other board, society, committee or advocacy group, paid or unpaid unrelated to current work presented here: DeCOG, German dermatological cooperative oncology group\u2014unrelated to current work presented here. Petra Staubach: Grants or contracts from any entity: Novartis; Allmirall | Consulting fees: AbbVie, Allergika, Almirall-Hermal, Amgen, Beiersdorf, Biocryst, BMS, Boehringer-Ingelheim, Celgene, CSL-Behring, Eli Lilly, Falk, Galderma, Hexal, Janssen, Klinge, Klosterfrau, LEO-Pharma, LETI-Pharma, L\u2019Oreal, Novartis, Octapharma, Pfizer, Pfl\u00fcger, Pharming, Regeneron, Shire, Takeda, Sanofi-Genzyme, UCB Pharma | Leadership or fiduciary role in other board, society, committee or advocacy group, paid or unpaid unrelated to current work presented here: Society of dermopharmazie, UNEV. Alexandra Strobel: Nothing to declare. Marcus Heise: Nothing to declare. Katharina Hennig: CEO and stakeholder of LENICURA GmbH. Georgios Nikolakis: Consulting fees\u2014Dessau Medical Center received a consulting fee from M\u00f6lnlycke Health Care GmbH, for which I served as a consulting physician | Payment or honoraria for lectures, presentations, speakers bureaus, manuscript writing or educational events: Speaker for the EADV HS Course 28\u201330.11.2022, Porto, Portugal | Support for attending meetings and\/or travel: Elli Lilly Scholarship for attending EADV 2021 | Participation in a data protection monitoring board or advisory board\u2014Dessau Medical Center received a consulting fee from M\u00f6lnlycke Health Care GmbH, for which I served as a consulting physician, travel grants from Abbvie. Uwe Kirschner: Consulting Fees: Novartis | Payment or honoraria for lectures, presentations, speakers bureaus, manuscript writing or educational events: Novartis | Participation on a data protection monitoring board or advisory board: Novartis, EsmAiL, EpiCAi | Leadership or fiduciary role in other board, society, committee or advocacy group, paid or unpaid: Deutsche Gesellschaft f\u00fcr Wundheilung und Wundbehandlung. Jacek C Szepietowski: Advisory Board\/Consultant for AbbVie, Leo Pharma, Novartis, Pfizer, Sanofi-Genzyme, Trevi, UCB and Vifor; Speaker for AbbVie, Almirall, Janssen-Cilag, Eli Lilly, Leo Pharma, Novartis, Pfizer, Sanofi-Genzyme; Investigator for for AbbVie, Almirall, Amgen, AnaptysBio, BMS, Boehringer Ingelheim, Celtrion, Galderma, Galapagos, Helm AG, Kliniksa, Incyte, InfraRX, Janssen-Cilag, Leo Pharma, Medimmune, Menlo Therapeutics, Merck, Novartis, Pfizer, Regeneron, UCB, Teva, Trevi. Jacek C. Szepietowski is an Editorial Board member of<i> Dermatology and Therapy<\/i>. Jacek C. Szepietowski was not involved in the selection of peer reviewers for the manuscript nor any of the subsequent editorial decisions.. Lukasz Matusiak: Advisory Board\/Consultant for AbbVie, Novartis; Speaker for AbbVie, Aristo, Leo Pharma, Medac; Investigator for for AbbVie, Almirall, Amgen, AnaptysBio, BMS, Boehringer Ingelheim, Celtrion, Galderma, Galapagos, Helm AG, Kliniksa, Incyte, InfraRX, Janssen-Cilag, Leo Pharma, Medimmune, Menlo Therapeutics, Merck, Novartis, Pfizer, Regeneron, UCB, Teva, Trevi. Piotr Krajewski: Nothing to declare. Esther von Stebut: Consulting fees: Janssen, Novartis | Payment or honoraria for lectures, presentations, speakers bureaus, manuscript writing or educational events: Janssen, Novartis, Infectopharm, Leo | Leadership or fiduciary role in other board, society, committee or advocacy group, paid or unpaid: Deutsche Dermatologische Gesellschaft, Deutsche Forschungsgemeinschaft, Mediziner Fakult\u00e4tentag). Hans Bayer, Simone Garcovich: No conflict of interest to this manuscript.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"The study was conducted following the Declaration of Helsinki and was approved by the Ethics Committee Rhineland-Palatinate ethics committee, and was registered with the German Register for Clinical Trials under the identifier DRKS00025315.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}}]}}