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Xiang Rong DAI, and Xiao Hui YU are the staffs employed by Zhaoke Pharmaceutical (Hefei) Company Limited. Qiu Ju YIN is the staff employed by Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Limited; The other authors declare no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"The trial was conducted in accordance with the Good Clinical Practice guidelines and complies with the Declaration of Helsinki. The protocol and informed consent form were reviewed and approved by a properly constituted institutional review board\/independent ethics committee\/research ethics board before study commencement. The names of the approving ethics committees are listed in\u00a0Supplementary Table\u00a0.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval"}}]}}