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Jan Hugo has served as consultant and speaker for AbbVie, Amgen, Eli Lilly, Janssen Cilaq, LEO Pharma, Novartis, Pfizer, and UCB. Kristina Fuzesiova has served as a speaker for AbbVie, Eli Lilly and UCB. Tom\u00e1\u0161 Dole\u017eal has served as a speaker and consultant for AbbVie, Amgen, Eli Lilly, Janssen Cilaq, LEO Pharma, Novartis, Pfizer, and UCB. Barbora Turkova has nothing to declare. Spyridon Gkalpakiotis has served as consultants, speakers, or investigators for AbbVie, Amgen, Eli Lilly, Janssen Cilaq, LEO Pharma, Novartis, Pfizer, and UCB.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interests"}},{"value":"The study was conducted in accordance with the Helsinki Declaration of 1964 and all subsequent amendments, and all patients provided informed consent. 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